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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:generalized anxiety disorder
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Accession:DOID:14320 term browser browse the term
Definition:An anxiety disorder that is characterized by long-lasting anxiety that is not focused on any one object or situation. (DO)
Synonyms:primary_id: RDO:9002663
 xref: ICD10CM:F41.1;   ICD9CM:300.02;   NCI:C92622
For additional species annotation, visit the Alliance of Genome Resources.


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generalized anxiety disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gper1 G protein-coupled estrogen receptor 1 severity ISO protein:increased expression:serum (human) RGD PMID:27512921 RGD:39938860 NCBI chr12:17,309,122...17,315,267
Ensembl chr12:17,309,834...17,311,112
JBrowse link
G Slc6a4 solute carrier family 6 member 4 treatment ISO DNA:repeats, haplotype:promoter: RGD PMID:22907732 RGD:36947386 NCBI chr10:63,153,656...63,188,377
Ensembl chr10:63,153,651...63,176,463
JBrowse link
G Zfp462 zinc finger protein 462 ISS MouseDO NCBI chr 5:71,679,841...71,824,077
Ensembl chr 5:71,742,911...71,823,139
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17129
    disease of anatomical entity 16476
      nervous system disease 12074
        central nervous system disease 10353
          brain disease 9712
            disease of mental health 7022
              cognitive disorder 1949
                anxiety disorder 166
                  generalized anxiety disorder 3
paths to the root