Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:neonatal myasthenia gravis
go back to main search page
Accession:DOID:14043 term browser browse the term
Definition:A disorder of neuromuscular transmission that occurs in a minority of newborns born to women with myasthenia gravis. Clinical features are usually present at birth or develop in the first 3 days of life and consist of hypotonia and impaired respiratory, suck, and swallowing abilities. This condition is associated with the passive transfer of acetylcholine receptor antibodies through the placenta. In the majority of infants the myasthenic weakness resolves (i.e., transient neonatal myasthenia gravis) although this disorder may rarely continue beyond the neonatal period (i.e., persistent neonatal myasthenia gravis). (From Menkes, Textbook of Child Neurology, 5th ed, p823; Neurology 1997 Jan;48(1):50-4)
Synonyms:exact_synonym: antenatal myasthenia gravis;   persistent neonatal myasthenia gravis;   transient neonatal myasthenia gravis
 primary_id: MESH:D020941
 xref: EFO:1001059;   ICD9CM:775.2
For additional species annotation, visit the Alliance of Genome Resources.



show annotations for term's descendants           Sort by:

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16180
    disease of anatomical entity 15794
      musculoskeletal system disease 8139
        autoimmune disease of musculoskeletal system 936
          myasthenia gravis 34
            neonatal myasthenia gravis 0
Path 2
Term Annotations click to browse term
  disease 16180
    disease of anatomical entity 15794
      Immune & Inflammatory Diseases 5353
        immune system disease 4626
          primary immunodeficiency disease 4021
            autoimmune disease 2110
              autoimmune disease of the nervous system 607
                autoimmune disease of peripheral nervous system 57
                  myasthenia gravis 34
                    neonatal myasthenia gravis 0
paths to the root