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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:lung cancer
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Accession:DOID:1324 term browser browse the term
Definition:A respiratory system cancer that is located_in the lung. (DO)
Synonyms:exact_synonym: cancer of lung;   cancer of the lung;   lung cancers;   pulmonary cancer;   pulmonary cancers
 narrow_synonym: EGFR-RELATED LUNG CANCER;   adenocarcinoma of lung;   lung cancer, somatic
 broad_synonym: CHRNA3-RELATED CONDITION;   EGFR-RELATED CONDITION
 related_synonym: ADENOCARCINOMA OF LUNG, SUSCEPTIBILITY TO;   Adenocarcinoma of lung, response to tyrosine kinase inhibitor in, somatic;   LNCR1;   LNCR2;   LNCR3;   LNCR4;   LNCR5;   LUNG CANCER, PROTECTION AGAINST;   LUNG CANCER, PROTECTION AGAINST, IN SMOKERS;   lung cancer susceptibility 1;   lung cancer susceptibility 2;   lung cancer susceptibility 3;   lung cancer susceptibility 4;   lung cancer susceptibility 5;   lung cancer, susceptibility to
 xref: ICD10CM:C34.1;   ICD10CM:C34.2;   ICD10CM:C34.3;   ICD9CM:162.3;   ICD9CM:162.4;   ICD9CM:162.5;   ICD9CM:162.8;   MIM:211980;   MIM:608935;   MIM:612052;   MIM:612571;   MIM:612593;   MIM:614210;   MONDO:0008903
For additional species annotation, visit the Alliance of Genome Resources.

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show annotations for term's descendants           Sort by:
lung cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) treatment ISO RGD PMID:35289739 RGD:153344587 NCBI chr 5:14,972,589...15,164,594
Ensembl chr 5:14,972,646...15,164,567 		JBrowse link
G ACSL3 acyl-CoA synthetase long chain family member 3 ISO RGD PMID:23936004 RGD:13831302 NCBI chr10:108,787,341...108,867,523
Ensembl chr10:108,787,061...108,869,042 		JBrowse link
G ACTA2 actin alpha 2, smooth muscle ISO ClinVar Annotator: match by term: LUNG CANCER, SUSCEPTIBILITY TO ClinVar PMID:15937082 PMID:25741868 NCBI chr 9:82,358,937...82,376,289
Ensembl chr 9:82,359,086...82,372,446 		JBrowse link
G ALK ALK receptor tyrosine kinase ISO ClinVar Annotator: match by term: EGFR-related lung cancer | ClinVar Annotator: match by term: Lung cancer ClinVar PMID:20979473 PMID:21575866 PMID:22277784 PMID:24327273 PMID:24670165 More... NCBI chr14:77,632,809...78,408,307 JBrowse link
G ALX4 ALX homeobox 4 ISO DNA:hypermethylation:CpG_island: RGD PMID:24037716 RGD:153344522 NCBI chr 1:21,051,413...21,099,159
Ensembl chr 1:21,051,580...21,097,605 		JBrowse link
G ATM ATM serine/threonine kinase ISO ClinVar Annotator: match by term: Lung cancer ClinVar PMID:25741868 NCBI chr 1:99,653,208...99,786,889
Ensembl chr 1:99,653,139...99,791,520 		JBrowse link
G ATR ATR serine/threonine kinase treatment ISO RGD PMID:25010037 RGD:150340694 NCBI chr15:48,048,785...48,173,120
Ensembl chr15:48,048,882...48,173,137 		JBrowse link
G AXIN1 axin 1 disease_progression
treatment		 ISO DNA:hypermethylation
human cells in mouse model
protein:decreased expression:lung (human)		 RGD PMID:21496867 PMID:23192643 PMID:23915259 PMID:32051824 RGD:150527862 RGD:150530274 RGD:150530284 RGD:150530293 NCBI chr 5:233,520...295,134
Ensembl chr 5:234,060...290,575 		JBrowse link
G AXIN2 axin 2 susceptibility ISO DNA:SNP:exon:148T>C(rs2240308)(human)
DNA:SNPs:exons,introns:		 RGD PMID:25091576 PMID:28378643 RGD:151356504 RGD:151356659 NCBI chr16:55,874,043...55,906,739
Ensembl chr16:55,874,072...55,907,281 		JBrowse link
G BARD1 BRCA1 associated RING domain 1 ISO ClinVar Annotator: match by term: Lung cancer ClinVar PMID:19197335 PMID:20077502 PMID:25741868 PMID:26467025 PMID:26738429 More... NCBI chr10:100,539,827...100,627,718
Ensembl chr10:100,539,527...100,627,675 		JBrowse link
G BMP2 bone morphogenetic protein 2 ISO ClinVar Annotator: match by term: Lung cancer ClinVar PMID:21515830 PMID:24465802 PMID:26253951 NCBI chr 2:31,349,394...31,361,227
Ensembl chr 2:31,348,808...31,360,901 		JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: EGFR-related lung cancer | ClinVar Annotator: match by term: Lung cancer, somatic OMIM
ClinVar		 PMID:16439621 PMID:16474404 PMID:17366577 PMID:17551924 PMID:17703371 More... NCBI chr21:109,495,525...109,690,261 JBrowse link
G BRCA1 BRCA1 DNA repair associated ISO ClinVar Annotator: match by term: Lung cancer, somatic ClinVar PMID:8554067 PMID:9760198 PMID:10486320 PMID:10505028 PMID:11260866 More... NCBI chr16:63,162,827...63,243,928 JBrowse link
G CA12 carbonic anhydrase 12 ISO protein:increased expression:serum; RGD PMID:22439015 RGD:155226862 NCBI chr26:20,162,706...20,221,680
Ensembl chr26:20,162,926...20,224,502 		JBrowse link
G CALR calreticulin treatment ISO protein:increased expression:blood serum (human)
human cells and recombinant gene in a mouse model		 RGD PMID:12215887 PMID:22083347 PMID:24111870 PMID:26314964 PMID:32161598 RGD:150520159 RGD:150521678 RGD:150521699 RGD:150521700 RGD:150521704 NCBI chr 6:11,618,691...11,624,299
Ensembl chr 6:11,618,396...11,623,792 		JBrowse link
G CASP8 caspase 8 ISO ClinVar Annotator: match by term: Lung cancer | ClinVar Annotator: match by term: Lung cancer, protection against OMIM
ClinVar		 PMID:17450141 PMID:18305469 PMID:25741868 NCBI chr10:86,888,654...86,944,159
Ensembl chr10:86,916,527...86,943,829 		JBrowse link
G CCDC116 coiled-coil domain containing 116 ISO DNA:SNP:promoter:rs3747093 (human) RGD PMID:29193083 RGD:153297750 NCBI chr19:4,472,976...4,478,265
Ensembl chr19:4,473,531...4,477,137 		JBrowse link
G CCL22 C-C motif chemokine ligand 22 disease_progression ISO RGD PMID:16453150 RGD:4891472
G CD164 CD164 molecule exacerbates ISO protein:increased expression:lung (human) RGD PMID:28903328 RGD:11555304 NCBI chr13:64,482,079...64,498,540
Ensembl chr13:64,481,790...64,499,135 		JBrowse link
G CDC73 cell division cycle 73 exacerbates ISO mRNA:increased expression:lung (human) RGD PMID:29221126 RGD:150539444 NCBI chr25:36,167,482...36,302,918
Ensembl chr25:36,170,134...36,302,812 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B disease_progression ISO protein:decreased expression:lung (rat) RGD PMID:20512841 RGD:152998913 NCBI chr11:12,612,064...12,617,228
Ensembl chr11:12,612,079...12,617,531 		JBrowse link
G CDKN1C cyclin dependent kinase inhibitor 1C disease_progression ISO protein:decreased expression:lung (rat)
DNA:hypermethylation:promoter (rat)		 RGD PMID:20512841 RGD:152998913 NCBI chr 1:2,696,382...2,699,054
Ensembl chr 1:2,696,233...2,699,028 		JBrowse link
G CFTR CF transmembrane conductance regulator susceptibility ISO DNA:deletion, SNP, haplotype: :p.F508del, rs10487372 (human) RGD PMID:20116881 RGD:11566029 NCBI chr21:86,154,313...86,332,436 JBrowse link
G CHD4 chromodomain helicase DNA binding protein 4 ameliorates ISO DNA:missense mutation:CDS p.D140E (rs7479004) (human)
mRNA:increased expression:lung (human)		 RGD PMID:25407497 PMID:30031117 RGD:153323305 RGD:153323309 NCBI chr11:6,603,820...6,641,278
Ensembl chr11:6,602,694...6,640,351 		JBrowse link
G CHEK2 checkpoint kinase 2 ISO ClinVar Annotator: match by term: Lung cancer, somatic ClinVar PMID:16883537 PMID:18484200 PMID:21244692 PMID:21618645 PMID:23318652 More... NCBI chr19:11,567,529...11,621,180
Ensembl chr19:11,567,528...11,604,792 		JBrowse link
G CHRNA3 cholinergic receptor nicotinic alpha 3 subunit onset
susceptibility		 ISO DNA:SNP:exon 2: rs8040868(T>C) (human)
ClinVar Annotator: match by term: Lung cancer susceptibility 2		 RGD
OMIM
ClinVar		 PMID:18385676 PMID:18385738 PMID:18385739 PMID:28492532 PMID:29416783 RGD:151361155 NCBI chr26:4,721,145...4,747,694
Ensembl chr26:4,722,489...4,737,164 		JBrowse link
G CHRNA5 cholinergic receptor nicotinic alpha 5 subunit susceptibility ISO ClinVar Annotator: match by term: Lung cancer susceptibility 2 ClinVar
OMIM		 PMID:18385738 PMID:18385739 PMID:18618000 PMID:19132693 PMID:19443489 More... NCBI chr26:4,747,734...4,779,231
Ensembl chr26:4,749,766...4,776,822 		JBrowse link
G CHRNA7 cholinergic receptor nicotinic alpha 7 subunit disease_progression ISO DNA:CNV:: CNV-3956(human) RGD PMID:25407004 RGD:11074492 NCBI chr26:50,554,143...50,686,847
Ensembl chr26:50,551,829...50,686,803 		JBrowse link
G CHRNB4 cholinergic receptor nicotinic beta 4 subunit susceptibility ISO DNA:SNP: :rs7178270(human)
DNA:SNP:3'utr: (rs1948)C>T (human)		 RGD PMID:20587604 PMID:29416783 RGD:150527839 RGD:151361155 NCBI chr26:4,700,217...4,717,363
Ensembl chr26:4,701,321...4,719,319 		JBrowse link
G CLPTM1L CLPTM1 like susceptibility
disease_progression
sexual_dimorphism		 ISO DNA:SNPs:: rs402710,rs451360 (human)
in males;DNA:SNP: :rs370348(human)
DNA:SNP:intron:rs31489(human)
associated with smoking; DNA:SNP:intron:rs31489(human)
DNA:SNPs::multiple (human)		 RGD PMID:21622582 PMID:21771723 PMID:24366883 PMID:25422207 PMID:25526467 More... RGD:150530483 RGD:150530484 RGD:150530494 RGD:150530631 RGD:150530642 RGD:150530643 RGD:150537097 NCBI chr 4:1,140,272...1,162,663
Ensembl chr 4:1,140,132...1,162,898 		JBrowse link
G COMT catechol-O-methyltransferase susceptibility ISO associated with nicotine dependence and alcohol dependence; DNA:SNP:exon 4: 472G>A, p.V158M (rs4680) (human) RGD PMID:27644662 RGD:401959228 NCBI chr19:5,775,829...5,803,260
Ensembl chr19:5,773,225...5,785,422 		JBrowse link
G CSF1R colony stimulating factor 1 receptor exacerbates
susceptibility		 ISO protein:increased expression:lung (human)
DNA:missense mutation:CDS:p.H362R (rs10079250) (human)		 RGD PMID:25144241 PMID:29323162 RGD:150524283 RGD:150524284 NCBI chr23:52,663,290...52,723,652
Ensembl chr23:52,664,076...52,697,304 		JBrowse link
G CTNNB1 catenin beta 1 treatment ISO human cells in mouse model RGD PMID:32051824 RGD:150530284 NCBI chr22:2,679,488...2,725,034
Ensembl chr22:2,684,022...2,723,949 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO associated with Pulmonary Emphysema;DNA:polymorphism: :p.I462V (human) RGD PMID:16696009 RGD:4892075 NCBI chr26:8,753,236...8,759,378
Ensembl chr26:8,753,327...8,759,384 		JBrowse link
G CYP24A1 cytochrome P450 family 24 subfamily A member 1 sexual_dimorphism ISO mRNA:increased expression:lung (human)
DNA:SNP:intron: (rs2765934) (human)		 RGD PMID:16180015 PMID:31264381 RGD:151361183 RGD:151665340 NCBI chr 2:9,868,794...9,889,510
Ensembl chr 2:9,868,678...9,885,884 		JBrowse link
G DAB2IP DAB2 interacting protein sexual_dimorphism ISO DNA:SNP:intron 1:97906C>A (rs1571801) (human) RGD PMID:22046421 RGD:151665197 NCBI chr12:17,802,030...18,017,648
Ensembl chr12:17,801,831...17,830,890 		JBrowse link
G DAGLA diacylglycerol lipase alpha ISO DNA:SNP:rs60507107 (human) RGD PMID:25592173 RGD:151356746 NCBI chr 1:12,110,100...12,175,935
Ensembl chr 1:12,108,810...12,136,105 		JBrowse link
G DHFR dihydrofolate reductase ISO ClinVar Annotator: match by term: Lung cancer, somatic ClinVar PMID:28492532 NCBI chr 4:74,787,292...74,811,196
Ensembl chr 4:74,787,629...74,810,960 		JBrowse link
G DICER1 dicer 1, ribonuclease III exacerbates ISO RGD PMID:19903759 RGD:149735199 NCBI chr24:72,915,550...72,986,658
Ensembl chr24:72,915,499...72,963,006 		JBrowse link
G DNAI7 dynein axonemal intermediate chain 7 ameliorates ISO DNA:missense mutation:CDS:p.N60S (mouse) RGD PMID:14583591 RGD:152998907 NCBI chr11:24,871,767...24,953,586
Ensembl chr11:24,875,416...24,953,375 		JBrowse link
G DNMT1 DNA methyltransferase 1 disease_progression ISO protein:increased expression:lung:
protein:increased expression:lung (human)		 RGD PMID:21496867 PMID:24548441 RGD:150530293 RGD:9588658 NCBI chr 6:9,199,006...9,263,890
Ensembl chr 6:9,199,003...9,263,607 		JBrowse link
G DNMT3A DNA methyltransferase 3 alpha disease_progression ISO protein:increased expression:lung: RGD PMID:24548441 RGD:9588658 NCBI chr14:82,313,414...82,427,170
Ensembl chr14:82,402,826...82,420,819 		JBrowse link
G DNMT3B DNA methyltransferase 3 beta disease_progression ISO protein:increased expression:lung: RGD PMID:24548441 RGD:9588658 NCBI chr 2:37,128,635...37,176,033
Ensembl chr 2:37,146,538...37,174,570 		JBrowse link
G DVL3 dishevelled segment polarity protein 3 ISO DNA:SNP:intron:rs1969253 (human) RGD PMID:29193083 RGD:153297750 NCBI chr15:5,254,764...5,270,661
Ensembl chr15:5,254,661...5,270,403 		JBrowse link
G EGFR epidermal growth factor receptor susceptibility ISO ClinVar Annotator: match by term: EGFR-related condition | ClinVar Annotator: match by term: EGFR-related lung cancer | ClinVar Annotator: match by term: Lung cancer | ClinVar Annotator: match by term: Lung cancer, somatic
ClinVar Annotator: match by term: Adenocarcinoma of lung, response to tyrosine kinase inhibitor in, somatic | ClinVar Annotator: match by term: EGFR-related condition | ClinVar Annotator: match by term: EGFR-related lung cancer | ClinVar Annotator: match by term: Lung cancer | ClinVar Annotator: match by term: Lung cancer, somatic		 ClinVar
OMIM		 PMID:7630400 PMID:9536098 PMID:11423618 PMID:15118073 PMID:15118125 More... NCBI chr21:3,664,622...3,853,492
Ensembl chr21:3,666,339...3,853,239 		JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 ISO OMIM NCBI chr16:66,435,488...66,464,993
Ensembl chr16:66,434,251...66,464,952 		JBrowse link
G ERCC5 ERCC excision repair 5, endonuclease susceptibility ISO mRNA:decreased expression:lung (human) RGD PMID:10910954 RGD:155260338 NCBI chr 3:81,406,103...81,441,422
Ensembl chr 3:81,405,872...81,436,040 		JBrowse link
G ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2 severity ISO RGD PMID:33573689 RGD:155791670 NCBI chr 8:25,885,823...25,919,863
Ensembl chr 8:25,887,309...25,916,630 		JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit susceptibility ISO DNA:SNPs, haplotype: :rs6950683, rs3757441 (human) RGD PMID:19901851 RGD:126781717 NCBI chr21:117,380,518...117,515,224
Ensembl chr21:117,380,361...117,421,573 		JBrowse link
G FASLG Fas ligand ISO ClinVar Annotator: match by term: Lung cancer, somatic ClinVar
OMIM		 PMID:17605793 PMID:25741868 PMID:28492532 NCBI chr25:56,488,572...56,496,469
Ensembl chr25:56,489,417...56,496,251 		JBrowse link
G FGF9 fibroblast growth factor 9 ISO OMIM:211980 | OMIM:608935 | OMIM:612571 | OMIM:612593 | OMIM:614210 MouseDO NCBI chr 3:1,779,126...1,811,427
Ensembl chr 3:1,779,192...1,812,784 		JBrowse link
G FOXA1 forkhead box A1 disease_progression ISO RGD PMID:31221478 RGD:151665930 NCBI chr24:14,397,759...14,403,078
Ensembl chr24:14,396,702...14,403,094 		JBrowse link
G FOXM1 forkhead box M1 ISO OMIM:211980 | OMIM:608935 | OMIM:612571 | OMIM:612593 | OMIM:614210 MouseDO NCBI chr11:2,920,903...2,941,011
Ensembl chr11:2,920,663...2,940,823 		JBrowse link
G GATA1 GATA binding protein 1 ISO mRNA:increased expression:regulatory T cell:lung associated T cell RGD PMID:28814673 RGD:149735197 NCBI chr  X:45,912,638...45,920,415
Ensembl chr  X:45,917,231...45,920,268 		JBrowse link
G GPX1 glutathione peroxidase 1 susceptibility
exacerbates		 ISO DNA:missense mutation:CDS:p.P198L (human)
DNA:missense mutation:CDS: (rs1050450) (human)
DNA:mutations:multiple (human)		 RGD PMID:11103801 PMID:15192016 PMID:16615267 PMID:23516596 PMID:32850411 RGD:152023634 RGD:152995449 RGD:152995450 RGD:152995506 RGD:152998903 NCBI chr22:10,754,976...10,756,617 JBrowse link
G GPX3 glutathione peroxidase 3 treatment ISO RGD PMID:26767034 PMID:33255360 RGD:151708705 RGD:151708707 NCBI chr23:53,576,950...53,585,321 JBrowse link
G HNRNPL heterogeneous nuclear ribonucleoprotein L severity ISO human gene in a mouse model RGD PMID:20972334 RGD:9999427 NCBI chr 6:33,452,705...33,469,070
Ensembl chr 6:33,452,852...33,466,284 		JBrowse link
G HS3ST2 heparan sulfate-glucosamine 3-sulfotransferase 2 ISO DNA:hypermethylation:promoter (human) RGD PMID:12527896 RGD:2317633 NCBI chr 5:20,511,329...20,612,114
Ensembl chr 5:20,511,762...20,611,336 		JBrowse link
G IL1R2 interleukin 1 receptor type 2 susceptibility ISO DNA:SNP:CDS:multiple (human) RGD PMID:30895747 RGD:152998976 NCBI chr14:5,672,434...5,708,270
Ensembl chr14:5,673,163...5,708,372 		JBrowse link
G IRF1 interferon regulatory factor 1 ISO OMIM NCBI chr23:35,309,058...35,317,765
Ensembl chr23:35,307,772...35,316,763 		JBrowse link
G IRS4 insulin receptor substrate 4 treatment ISO human cells in mouse model RGD PMID:33894221 RGD:151347872 NCBI chr  X:96,589,292...96,605,715
Ensembl chr  X:96,601,944...96,605,699 		JBrowse link
G KDM4A lysine demethylase 4A ISO protein:increased expression:lung (human) RGD PMID:23168260 RGD:9587434 NCBI chr20:89,108,090...89,164,657
Ensembl chr20:89,073,876...89,164,663 		JBrowse link
G KDM4B lysine demethylase 4B ISO mRNA, protein:increased expression:lung (human) RGD PMID:21930796 RGD:9587740 NCBI chr 6:4,649,140...4,831,634
Ensembl chr 6:4,649,221...4,831,636 		JBrowse link
G KDM6A lysine demethylase 6A exacerbates ISO RGD PMID:29632194 RGD:150429738 NCBI chr  X:42,053,272...42,291,013
Ensembl chr  X:42,053,336...42,290,526 		JBrowse link
G KMT2D lysine methyltransferase 2D ISO ClinVar Annotator: match by term: Lung cancer ClinVar PMID:25741868 NCBI chr11:45,260,873...45,303,898
Ensembl chr11:45,263,408...45,302,423 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: EGFR-related lung cancer | ClinVar Annotator: match by term: Lung cancer, somatic OMIM
ClinVar		 PMID:6320174 PMID:11745231 PMID:12110640 PMID:12460918 PMID:14982869 More... NCBI chr11:24,963,396...25,010,747
Ensembl chr11:24,973,619...25,005,191 		JBrowse link
G LOC103224275 glutathione S-transferase Mu 1 resistance ISO RGD PMID:19428374 RGD:4140941 NCBI chr20:23,854,969...23,861,634 JBrowse link
G LOC103231165 isocitrate dehydrogenase (NADP(+)) 2 ISO RGD PMID:30128035 RGD:149735564 NCBI chr29:8,633,429...8,650,744
Ensembl chr29:8,633,715...8,650,657 		JBrowse link
G LOC103244924 cyclin-G1 treatment ISO human cells in mouse model RGD PMID:25472877 RGD:151361106 NCBI chr23:65,709,759...65,716,913
Ensembl chr23:65,709,786...65,714,711 		JBrowse link
G LRP1B LDL receptor related protein 1B severity ISO DNA:mutations: :multiple (human) RGD PMID:33219256 RGD:150429789 NCBI chr10:25,611,400...27,511,903
Ensembl chr10:25,616,590...26,609,111 		JBrowse link
G MAP2K4 mitogen-activated protein kinase kinase 4 ameliorates ISO DNA:SNP:promoter: -1304T>G (rs3826392) (human) RGD PMID:20554746 RGD:150429822 NCBI chr16:11,366,610...11,485,411
Ensembl chr16:11,366,751...11,486,125 		JBrowse link
G MAP3K8 mitogen-activated protein kinase kinase kinase 8 exacerbates ISO RGD
OMIM		 PMID:26300007 RGD:11535492
G MAT2A methionine adenosyltransferase 2A treatment ISO human cells in mouse model RGD PMID:34258296 RGD:153350142 NCBI chr14:21,609,533...21,615,822
Ensembl chr14:21,611,040...21,615,615 		JBrowse link
G MBD1 methyl-CpG binding domain protein 1 susceptibility ISO DNA:snp::c.1221+135T>A (rs140689) (human)
DNA:snps, deletion:promoter, cds:g.-634G>A, g.-501delT, p.P401A (human)		 RGD PMID:16284366 PMID:18668384 RGD:9588651 RGD:9588657 NCBI chr18:30,675,419...30,690,111
Ensembl chr18:30,675,653...30,685,946 		JBrowse link
G MBD4 methyl-CpG binding domain 4, DNA glycosylase susceptibility ISO DNA:snp:cds:p.E346K (rs140693) (human) RGD PMID:18495292 RGD:9588970 NCBI chr22:51,616,840...51,626,232
Ensembl chr22:51,616,803...51,626,224 		JBrowse link
G MBL2 mannose binding lectin 2 susceptibility ISO DNA:polymorphisms:multiple (human) RGD PMID:19959685 RGD:4889433 NCBI chr 9:78,389,534...78,394,753
Ensembl chr 9:78,389,947...78,396,079 		JBrowse link
G MCL1 MCL1 apoptosis regulator, BCL2 family member ameliorates ISO human cells in mouse model
DNA:SNP:promoter:-190indel, -235C>A, (rs3831987,rs3738484)
protein:increased expression:lung (human)		 RGD PMID:21887682 PMID:28776569 PMID:31662324 RGD:151356915 RGD:151356930 RGD:151356991
G MEF2D myocyte enhancer factor 2D treatment ISO human cells in mouse model RGD PMID:25472877 RGD:151361106 NCBI chr20:7,358,647...7,394,068
Ensembl chr20:7,358,653...7,396,972 		JBrowse link
G MKI67 marker of proliferation Ki-67 ameliorates ISO human cells in mouse model RGD PMID:29183007 RGD:153344580 NCBI chr 9:120,697,183...120,727,039
Ensembl chr 9:120,698,834...120,726,866 		JBrowse link
G MLH1 mutL homolog 1 no_association
susceptibility		 ISO DNA:SNP: :9452A>T (rs1540354) (human)
ClinVar Annotator: match by term: Lung cancer
DNA:SNP: :rs1800734 (human)		 RGD
ClinVar		 PMID:21093954 PMID:25252909 PMID:25420488 PMID:26845104 PMID:28492532 More... RGD:126848792 RGD:126848798 NCBI chr15:2,364,537...2,418,379
Ensembl chr15:2,364,738...2,418,393 		JBrowse link
G MMP1 matrix metallopeptidase 1 susceptibility ISO DNA:insertion, haplotype:promoter:g.-1607insG (human)
DNA:insertion:promoter:g.-1607insG (human)
associated with Respiratory Tract Diseases		 RGD PMID:11691799 PMID:15718477 PMID:19963114 RGD:4890379 RGD:5131088 RGD:7207021 NCBI chr 1:94,167,507...94,177,357
Ensembl chr 1:94,167,219...94,176,767 		JBrowse link
G MMP3 matrix metallopeptidase 3 ISO protein:decreased expression:pleural fluid RGD PMID:20216542 RGD:5129491 NCBI chr 1:94,216,156...94,224,437
Ensembl chr 1:94,216,173...94,224,264 		JBrowse link
G MPO myeloperoxidase ISO ClinVar Annotator: match by term: Lung cancer, protection against, in smokers ClinVar PMID:11087769 PMID:12915675 PMID:15023809 PMID:17304047 NCBI chr16:35,120,194...35,130,851
Ensembl chr16:35,120,581...35,130,671 		JBrowse link
G MPZL3 myelin protein zero like 3 ISO DNA:SNP:UTR3:rs11216826 (human) RGD PMID:29193083 RGD:153297750 NCBI chr 1:109,609,152...109,631,914
Ensembl chr 1:109,604,671...109,631,990 		JBrowse link
G MSH2 mutS homolog 2 susceptibility ISO DNA:SNP: :rs2303425 (human) RGD PMID:25252909 RGD:126848798 NCBI chr14:59,730,101...59,802,857
Ensembl chr14:59,729,789...59,802,819 		JBrowse link
G MSH3 mutS homolog 3 ISO ClinVar Annotator: match by term: Lung cancer, somatic ClinVar PMID:28492532 NCBI chr 4:74,811,181...75,032,067
Ensembl chr 4:74,811,198...75,032,005 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor treatment ISO human cells in mouse model RGD PMID:32051824 RGD:150530284 NCBI chr 8:122,282,989...122,288,392
Ensembl chr 8:122,282,630...122,288,384 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor exacerbates ISO human cell line in a mouse model RGD PMID:22938463 RGD:150521529 NCBI chr15:1,276,804...1,281,811
Ensembl chr15:1,276,798...1,281,166 		JBrowse link
G NAT2 N-acetyltransferase 2 no_association
susceptibility		 ISO DNA:polymorphisms: : RGD PMID:15808403 PMID:19558213 RGD:5131605 RGD:5131861 NCBI chr 8:16,451,144...16,494,961
Ensembl chr 8:16,493,749...16,494,621 		JBrowse link
G NCOA6 nuclear receptor coactivator 6 ISO DNA:amplification:cds (human) RGD PMID:10567404 RGD:9590137 NCBI chr 2:39,013,364...39,129,723
Ensembl chr 2:39,013,232...39,129,658 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 ISO ClinVar Annotator: match by term: Lung cancer ClinVar NCBI chr10:62,789,647...62,825,651
Ensembl chr10:62,790,124...62,825,339 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 disease_progression
exacerbates		 ISO RGD PMID:26300007 RGD:11535492 NCBI chr 7:50,589,494...50,711,472
Ensembl chr 7:50,589,856...50,711,498 		JBrowse link
G NFKBIA NFKB inhibitor alpha susceptibility ISO DNA:polymorphisms:promoter:-826C>T,-881A>G (human) RGD PMID:26870106 RGD:13793394 NCBI chr24:12,211,619...12,216,185
Ensembl chr24:12,210,281...12,214,854 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 susceptibility ISO DNA:insertion: : 3020_3021insC (human) RGD PMID:16267612 RGD:5131514 NCBI chr 5:36,492,158...36,531,766
Ensembl chr 5:36,496,414...36,530,499 		JBrowse link
G PALB2 partner and localizer of BRCA2 ISO ClinVar Annotator: match by term: Lung cancer, somatic ClinVar PMID:17200668 PMID:17200671 PMID:17200672 PMID:24136930 PMID:25099575 More... NCBI chr 5:21,322,952...21,358,363
Ensembl chr 5:21,322,975...21,358,198 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO ClinVar Annotator: match by term: Lung cancer, somatic ClinVar
OMIM		 PMID:19366826 PMID:25157968 PMID:25741868 PMID:26619011 NCBI chr15:10,218,034...10,304,874
Ensembl chr15:10,218,805...10,294,316 		JBrowse link
G PLCG1 phospholipase C gamma 1 exacerbates ISO RGD PMID:33077911 RGD:151356960 NCBI chr 2:22,599,547...22,638,394 JBrowse link
G PML PML nuclear body scaffold ameliorates ISO RGD PMID:25486572 RGD:41404692 NCBI chr26:9,441,998...9,494,949
Ensembl chr26:9,451,112...9,494,931 		JBrowse link
G POLE DNA polymerase epsilon, catalytic subunit severity ISO DNA:missense mutation:CDS:p.A252V (human) RGD PMID:17855454 RGD:11567235 NCBI chr11:127,966,879...128,030,442
Ensembl chr11:127,965,896...128,030,292 		JBrowse link
G POT1 protection of telomeres 1 ISO DNA:SNP: : rs10244817 (human)
DNA:SNP: :rs116895242 (human)
DNA:SNP: :p.V326A (rs75932146) (human) 		RGD PMID:19285750 PMID:27459707 PMID:32514122 RGD:151356947 RGD:151356948 RGD:151356949 NCBI chr21:93,572,139...93,688,374
Ensembl chr21:93,571,272...93,655,869 		JBrowse link
G PPP2R1B protein phosphatase 2 scaffold subunit Abeta ISO OMIM NCBI chr 1:103,058,283...103,110,839
Ensembl chr 1:103,057,915...103,110,102 		JBrowse link
G PRDM1 PR/SET domain 1 disease_progression ISO RGD PMID:28378641 RGD:150530469 NCBI chr13:67,695,436...67,719,487
Ensembl chr13:67,695,309...67,718,931 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase ISO ClinVar Annotator: match by term: Lung cancer, somatic OMIM
ClinVar		 PMID:10824074 PMID:11179010 PMID:12730996 PMID:12764051 PMID:15090472 More... NCBI chr13:88,856,056...90,329,379 JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:21303331 RGD:5135048 NCBI chr25:42,733,535...42,742,463
Ensembl chr25:42,734,771...42,742,429 		JBrowse link
G RAC1 Rac family small GTPase 1 treatment ISO DNA:SNPs:enhancers, intron: (rs836554, rs4720672, rs12536544) (human) RGD PMID:27299748 RGD:155230814 NCBI chr28:15,583,609...15,610,753
Ensembl chr28:15,583,516...15,610,328 		JBrowse link
G RAD52 RAD52 homolog, DNA repair protein susceptibility ISO DNA:SNP,haplotype:
DNA:SNP: (rs4766394) (human)		 RGD PMID:18449888 PMID:22382497 RGD:151660351 RGD:151660503 NCBI chr11:893,984...989,119
Ensembl chr11:895,292...927,430 		JBrowse link
G RBM10 RNA binding motif protein 10 onset ISO RGD PMID:33219256 RGD:150429789 NCBI chr  X:44,339,653...44,373,509
Ensembl chr  X:44,339,877...44,373,339 		JBrowse link
G RECQL RecQ like helicase ISO RGD PMID:18422747 RGD:2317370 NCBI chr11:21,334,601...21,366,943
Ensembl chr11:21,331,584...21,366,979 		JBrowse link
G RICTOR RPTOR independent companion of MTOR complex 2 ISO DNA:amplification: :lung (human) RGD PMID:26370156 RGD:11535413 NCBI chr 4:37,758,531...37,885,323
Ensembl chr 4:37,762,901...37,873,766 		JBrowse link
G RNASET2 ribonuclease T2 ISO DNA:SNP:intergenic:rs444210 (human) RGD PMID:29193083 RGD:153297750 NCBI chr13:94,670,376...94,702,585
Ensembl chr13:94,668,580...94,702,587 		JBrowse link
G ROBO1 roundabout guidance receptor 1 ISO OMIM:211980 | OMIM:608935 | OMIM:612571 | OMIM:612593 | OMIM:614210 MouseDO NCBI chr22:97,178,093...98,363,647
Ensembl chr22:98,222,891...98,363,219 		JBrowse link
G RTEL1 regulator of telomere elongation helicase 1 susceptibility
ameliorates		 ISO DNA:SNP:cds:rs7261546|rs6062299|rs3787098 (human)
DNA:SNP:cds:rs2738789 (human)		 RGD PMID:27765928 RGD:152993553 NCBI chr 2:531,905...567,430
Ensembl chr 2:531,085...566,840 		JBrowse link
G SETDB1 SET domain bifurcated histone lysine methyltransferase 1 severity ISO human gene in a mouse model RGD PMID:23770855 RGD:9590160
G SFTPB surfactant protein B disease_progression ISO RGD PMID:24248694 PMID:28743125 RGD:151667422 RGD:151667423 NCBI chr14:21,487,424...21,497,491
Ensembl chr14:21,488,387...21,499,850 		JBrowse link
G SHOX2 SHOX homeobox 2 ISO RGD PMID:25331797 RGD:12859082 NCBI chr15:32,684,598...32,694,640
Ensembl chr15:32,684,705...32,692,699 		JBrowse link
G SLC22A18 solute carrier family 22 member 18 ISO OMIM NCBI chr 1:2,712,792...2,737,874
Ensembl chr 1:2,715,027...2,737,872 		JBrowse link
G SLCO1B3 solute carrier organic anion transporter family member 1B3 ISO mRNA:increased expression:lung (human) RGD PMID:25625007 RGD:152995427 NCBI chr11:20,637,429...20,760,577
Ensembl chr11:20,648,582...20,761,161 		JBrowse link
G SMAD3 SMAD family member 3 ISO ClinVar Annotator: match by term: Lung cancer ClinVar PMID:21515830 PMID:24465804 PMID:26253951 NCBI chr26:16,319,959...16,446,472
Ensembl chr26:16,320,933...16,446,527 		JBrowse link
G SMAD4 SMAD family member 4 ISO ClinVar Annotator: match by term: Lung cancer ClinVar PMID:21515830 PMID:24465805 PMID:25741868 PMID:26253951 NCBI chr18:29,894,157...29,951,445
Ensembl chr18:29,897,621...29,934,478 		JBrowse link
G SMAD9 SMAD family member 9 ISO ClinVar Annotator: match by term: Lung cancer ClinVar PMID:21515830 PMID:24465803 PMID:26253951 NCBI chr 3:15,369,119...15,444,599
Ensembl chr 3:15,372,933...15,405,836 		JBrowse link
G SOD2 superoxide dismutase 2 ISO RGD PMID:15213518 RGD:1581247 NCBI chr13:87,284,537...87,297,998
Ensembl chr13:87,280,686...87,297,974 		JBrowse link
G SOX30 SRY-box transcription factor 30 exacerbates ISO DNA:hypermethylation:lung: RGD PMID:25435374 RGD:151660338 NCBI chr23:60,013,384...60,038,682
Ensembl chr23:60,014,046...60,037,997 		JBrowse link
G SOX9 SRY-box transcription factor 9 disease_progression ISO mRNA:increased expression:lung RGD PMID:31221478 RGD:151665930 NCBI chr16:49,519,749...49,523,967
Ensembl chr16:49,518,185...49,523,898 		JBrowse link
G SRSF6 serine and arginine rich splicing factor 6 ISO mRNA:increased expression:lung (human) RGD PMID:23132731 RGD:11039482 NCBI chr 2:20,340,163...20,345,873
Ensembl chr 2:20,342,681...20,346,122 		JBrowse link
G STIM1 stromal interaction molecule 1 ameliorates ISO human cells in mouse model RGD PMID:27863410 RGD:152995356 NCBI chr 1:62,651,472...62,865,992
Ensembl chr 1:62,651,290...62,865,986 		JBrowse link
G TERT telomerase reverse transcriptase ISO mRNA:increased expression:lung RGD PMID:10969652 RGD:152977758 NCBI chr 4:1,082,894...1,119,373
Ensembl chr 4:1,083,384...1,117,468 		JBrowse link
G TNC tenascin C ISO protein:increased expression:lung RGD PMID:16928692 RGD:4889612 NCBI chr12:24,457,616...24,556,194
Ensembl chr12:24,457,738...24,556,451 		JBrowse link
G TP63 tumor protein p63 ISO DNA:SNP:intron:rs12696594 (human) RGD PMID:29193083 RGD:153297750 NCBI chr15:83,861,489...84,126,675 JBrowse link
G TP73 tumor protein p73 susceptibility ISO DNA:SNPs:exon 2:4G>A, 14C>T (human) RGD PMID:11139314 PMID:32063627 RGD:151347583 RGD:2291830 NCBI chr20:127,958,002...128,035,792
Ensembl chr20:127,958,809...128,013,691 		JBrowse link
G TRPC4 transient receptor potential cation channel subfamily C member 4 susceptibility ISO DNA:SNPs:: (rs9547991, rs978156) (human) RGD PMID:27617218 RGD:152995362 NCBI chr 3:16,135,822...16,358,902 JBrowse link
G TRPC7 transient receptor potential cation channel subfamily C member 7 susceptibility ISO DNA:SNPs:: (rs11748198) (human) RGD PMID:27617218 RGD:152995362 NCBI chr23:38,957,128...39,098,615 JBrowse link
G TTR transthyretin disease_progression
sexual_dimorphism		 ISO protein:decreased expression:blood serum (human) RGD PMID:17683510 PMID:20964562 RGD:151664742 RGD:151664750 NCBI chr18:49,124,302...49,131,495
Ensembl chr18:49,124,121...49,131,399 		JBrowse link
G WT1 WT1 transcription factor ISO mRNA:decreased expression:lung (human) RGD PMID:27821145 RGD:153344578 NCBI chr 1:32,750,300...32,801,832 JBrowse link
G XPC XPC complex subunit, DNA damage recognition and repair factor ISO OMIM:211980 | OMIM:608935 | OMIM:612571 | OMIM:612593 | OMIM:614210 MouseDO NCBI chr22:50,088,019...50,121,584
Ensembl chr22:50,085,353...50,121,542 		JBrowse link
G XRCC1 X-ray repair cross complementing 1 susceptibility
no_association
onset
severity		 ISO DNA:missense mutation:exon 17: c.1804C>A, p.P602T (human)
DNA:SNP, haplotype:5'utr: 77T>C (rs3213245) (human)
DNA:SNPs, haplotypes:exon 6, exon 7: p.R194W, p.P206P (rs179978, rs915927) (human)
DNA:missense mutation:exon 10: p.R399Q (rs25487) (human)
DNA:missense mutation:cds: p.R399Q (human)
DNA:SNP:exon 10: c.1178G>A, p.R393H (human)
DNA:missense mutation:exon 10: p.R399Q (human)
DNA:missense mutations:cds: p.R399Q, p.R194W (human)
DNA:missense mutation:exon 10: p.R399Q, 28152G>A (human)		 RGD PMID:15705867 PMID:16652158 PMID:17531525 PMID:17952468 PMID:19061777 More... RGD:11056906 RGD:151232296 RGD:151236316 RGD:151347172 RGD:151347407 RGD:151347416 RGD:151347426 RGD:151347439 RGD:151347450 NCBI chr 6:37,062,149...37,095,138
Ensembl chr 6:37,060,439...37,095,094 		JBrowse link
G XRN2 5'-3' exoribonuclease 2 susceptibility ISO DNA:snp:intron:c.2171-314T>C (rs2025811) (human) RGD PMID:19915612 RGD:11041753 NCBI chr 2:50,287,718...50,373,869
Ensembl chr 2:50,288,073...50,373,883 		JBrowse link
adenosquamous lung carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TTR transthyretin ISO protein:increased expression:lung (human) RGD PMID:26943652 RGD:151665207 NCBI chr18:49,124,302...49,131,495
Ensembl chr18:49,124,121...49,131,399 		JBrowse link
asbestos-related lung carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM28 ADAM metallopeptidase domain 28 ISO associated with lung adenocarcinoma ;mRNA:increased expression:lung RGD PMID:20544843 RGD:153298907 NCBI chr 8:22,424,260...22,483,878
Ensembl chr 8:22,430,579...22,488,257 		JBrowse link
G KIF5A kinesin family member 5A susceptibility ISO protein:increased expression:serum (human) RGD PMID:21231887 RGD:12793066 NCBI chr11:53,458,795...53,493,801 JBrowse link
G RARB retinoic acid receptor beta ISO DNA:hypomethylation:lung RGD PMID:28722770 RGD:13503322 NCBI chr15:69,851,447...70,266,215
Ensembl chr15:70,096,117...70,264,905 		JBrowse link
bronchiolo-alveolar adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALX4 ALX homeobox 4 ameliorates ISO RGD PMID:24037716 RGD:153344522 NCBI chr 1:21,051,413...21,099,159
Ensembl chr 1:21,051,580...21,097,605 		JBrowse link
G CCND1 cyclin D1 ISO protein:increased expression:lung RGD PMID:14674039 RGD:13434930 NCBI chr 1:4,909,616...4,922,272
Ensembl chr 1:4,907,353...4,922,357 		JBrowse link
G DNMT1 DNA methyltransferase 1 disease_progression ISO RGD PMID:19484794 RGD:4140940 NCBI chr 6:9,199,006...9,263,890
Ensembl chr 6:9,199,003...9,263,607 		JBrowse link
G EGFR epidermal growth factor receptor ISO DNA:snp:cds:p.T790M (human)
DNA:mutations:exons:
protein:increased expression:tumor (human)		 RGD PMID:15737014 PMID:21419590 PMID:26059825 RGD:11075076 RGD:5131465 RGD:5131630 NCBI chr21:3,664,622...3,853,492
Ensembl chr21:3,666,339...3,853,239 		JBrowse link
G EGR1 early growth response 1 ISO mRNA:decreased expression:tumor (human) RGD PMID:11948124 RGD:5131942 NCBI chr23:41,139,636...41,143,598
Ensembl chr23:41,140,065...41,142,374 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 ISO DNA:hypermethylation:promoter (human) RGD PMID:19484794 RGD:4140940 NCBI chr 1:6,676,897...6,679,936 JBrowse link
G KRAS KRAS proto-oncogene, GTPase ISO DNA:mutations:cds: RGD PMID:26059825 RGD:11075076 NCBI chr11:24,963,396...25,010,747
Ensembl chr11:24,973,619...25,005,191 		JBrowse link
G TP53 tumor protein p53 ISO DNA:mutations:exons: RGD PMID:26059825 RGD:11075076 NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223 		JBrowse link
bronchus carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSTP1 glutathione S-transferase pi 1 ISO mRNA:decreased expression:bronchus, epithelial cell RGD PMID:10749130 RGD:4142527 NCBI chr 1:6,676,897...6,679,936 JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO protein:increased secretion:lung (human) RGD PMID:18764914 RGD:4145523 NCBI chr 6:9,320,991...9,338,125
Ensembl chr 6:9,322,550...9,338,263 		JBrowse link
G IL10 interleukin 10 ISO protein:increased expression:lung RGD PMID:8030748 RGD:4143231 NCBI chr25:22,590,389...22,595,877
Ensembl chr25:22,590,962...22,594,836 		JBrowse link
G IL1RN interleukin 1 receptor antagonist ISO protein:increased expression, alternative forms:lung RGD PMID:8030748 RGD:4143231 NCBI chr14:16,136,667...16,152,451
Ensembl chr14:16,146,333...16,151,326 		JBrowse link
DICER1 syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASB2 ankyrin repeat and SOCS box containing 2 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr24:71,687,282...71,730,684
Ensembl chr24:71,687,238...71,730,696 		JBrowse link
G BTBD7 BTB domain containing 7 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr24:70,979,273...71,084,485
Ensembl chr24:70,979,232...71,041,628 		JBrowse link
G COX8C cytochrome c oxidase subunit 8C ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr24:71,098,014...71,099,417
Ensembl chr24:71,098,346...71,099,180 		JBrowse link
G DDX24 DEAD-box helicase 24 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr24:71,808,721...71,838,268
Ensembl chr24:71,808,995...71,838,262 		JBrowse link
G DICER1 dicer 1, ribonuclease III ISO ClinVar Annotator: match by term: DICER1 syndrome OMIM
ClinVar		 PMID:9295070 PMID:9345104 PMID:9536098 PMID:15242644 PMID:15987463 More... NCBI chr24:72,915,550...72,986,658
Ensembl chr24:72,915,499...72,963,006 		JBrowse link
G FAM181A family with sequence similarity 181 member A ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr24:71,678,583...71,682,815 JBrowse link
G GSC goosecoid homeobox ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr24:72,581,639...72,585,745
Ensembl chr24:72,581,915...72,583,423 		JBrowse link
G IFI27 interferon alpha inducible protein 27 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr24:71,884,130...71,890,813 JBrowse link
G IFI27L2 interferon alpha inducible protein 27 like 2 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr24:71,901,911...71,903,794
Ensembl chr24:71,901,852...71,903,831 		JBrowse link
G OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr24:71,783,388...71,806,721
Ensembl chr24:71,795,047...71,803,732 		JBrowse link
G PPP4R4 protein phosphatase 4 regulatory subunit 4 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr24:71,945,572...72,054,841
Ensembl chr24:71,945,868...72,055,279 		JBrowse link
G PRIMA1 proline rich membrane anchor 1 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr24:71,466,023...71,540,482 JBrowse link
G SERPINA1 serpin family A member 1 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr24:72,158,521...72,171,139
Ensembl chr24:72,156,784...72,163,500 		JBrowse link
G SERPINA10 serpin family A member 10 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr24:72,059,523...72,069,989
Ensembl chr24:72,058,780...72,069,085 		JBrowse link
G SERPINA11 serpin family A member 11 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr24:72,223,849...72,236,880
Ensembl chr24:72,223,638...72,232,543 		JBrowse link
G SERPINA12 serpin family A member 12 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr24:72,273,041...72,285,367
Ensembl chr24:72,273,186...72,285,157 		JBrowse link
G SERPINA3 serpin family A member 3 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr24:72,388,948...72,415,746
Ensembl chr24:72,402,560...72,415,507 		JBrowse link
G SERPINA4 serpin family A member 4 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr24:72,345,566...72,356,257
Ensembl chr24:72,347,261...72,356,416 		JBrowse link
G SERPINA5 serpin family A member 5 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr24:72,369,082...72,388,439
Ensembl chr24:72,381,119...72,384,903 		JBrowse link
G SERPINA6 serpin family A member 6 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr24:72,079,084...72,098,549
Ensembl chr24:72,077,274...72,098,154 		JBrowse link
G SERPINA9 serpin family A member 9 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr24:72,247,517...72,255,199
Ensembl chr24:72,248,001...72,254,999 		JBrowse link
G UBR7 ubiquitin protein ligase E3 component n-recognin 7 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr24:70,945,412...70,969,489
Ensembl chr24:70,945,629...70,969,594 		JBrowse link
G UNC79 unc-79 homolog, NALCN channel complex subunit ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr24:71,172,214...71,455,415
Ensembl chr24:71,209,614...71,456,568 		JBrowse link
large cell neuroendocrine carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC7A5 solute carrier family 7 member 5 disease_progression ISO RGD PMID:18440724 RGD:151361285 NCBI chr 5:73,229,953...73,269,801
Ensembl chr 5:73,229,951...73,269,754 		JBrowse link
lung adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCE1 ATP binding cassette subfamily E member 1 severity ISO mRNA, protein:increased expression:lung (human) RGD PMID:18788636 RGD:11046260 NCBI chr 7:91,673,359...91,704,774 JBrowse link
G ACSL4 acyl-CoA synthetase long chain family member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr  X:97,488,414...97,575,251 JBrowse link
G ADAM19 ADAM metallopeptidase domain 19 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr23:59,867,949...59,966,873
Ensembl chr23:59,867,596...59,966,802 		JBrowse link
G ADAM28 ADAM metallopeptidase domain 28 treatment
disease_progression
exacerbates		 ISO protein:increased expression:lung RGD PMID:20112342 PMID:26800504 PMID:29882245 PMID:30190423 RGD:11531771 RGD:153297792 RGD:153297794 RGD:153297795 NCBI chr 8:22,424,260...22,483,878
Ensembl chr 8:22,430,579...22,488,257 		JBrowse link
G ADAMTSL3 ADAMTS like 3 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr29:1,592,205...1,974,406
Ensembl chr29:1,592,300...1,972,722 		JBrowse link
G ADGRG6 adhesion G protein-coupled receptor G6 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr13:30,810,167...30,951,082
Ensembl chr13:30,809,634...30,950,767 		JBrowse link
G AHCY adenosylhomocysteinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 2:38,579,254...38,601,218
Ensembl chr 2:38,579,024...38,601,208 		JBrowse link
G AHR aryl hydrocarbon receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:12597446 NCBI chr21:40,778,198...40,826,491
Ensembl chr21:40,778,218...40,826,478 		JBrowse link
G AKR1A1 aldo-keto reductase family 1 member A1 disease_progression ISO RGD PMID:30727821 RGD:27226687 NCBI chr20:87,228,348...87,245,511
Ensembl chr20:87,228,189...87,245,466 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung ClinVar PMID:17611497 PMID:18256540 PMID:18392055 PMID:18504432 PMID:18611285 More... NCBI chr24:82,704,087...82,730,711
Ensembl chr24:82,704,068...82,727,698 		JBrowse link
G ALB albumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr 7:21,872,036...21,890,095
Ensembl chr 7:21,876,132...21,891,407 		JBrowse link
G ALDH18A1 aldehyde dehydrogenase 18 family member A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 9:88,773,493...88,823,438 JBrowse link
G ALDOA aldolase, fructose-bisphosphate A ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 Ensembl chr 5:26,588,868...26,592,112 JBrowse link
G ALK ALK receptor tyrosine kinase ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:18923525 PMID:20979473 PMID:21030459 PMID:21575866 PMID:21791641 More... NCBI chr14:77,632,809...78,408,307 JBrowse link
G ALOX12B arachidonate 12-lipoxygenase, 12R type ISO CTD Direct Evidence: marker/mechanism CTD PMID:30258081 NCBI chr16:7,454,950...7,470,949
Ensembl chr16:7,455,044...7,469,934 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:30258081 NCBI chr 9:41,085,257...41,145,760
Ensembl chr 9:41,085,361...41,145,331 		JBrowse link
G ALX1 ALX homeobox 1 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr11:80,687,799...80,717,886
Ensembl chr11:80,696,271...80,717,574 		JBrowse link
G ALX4 ALX homeobox 4 disease_progression ISO RGD PMID:18978557 RGD:153350135 NCBI chr 1:21,051,413...21,099,159
Ensembl chr 1:21,051,580...21,097,605 		JBrowse link
G ANAPC2 anaphase promoting complex subunit 2 severity ISO mRNA:decreased expression:lung (human) RGD PMID:12036940 RGD:14696682 NCBI chr12:1,000,885...1,014,710
Ensembl chr12:1,000,952...1,016,261 		JBrowse link
G ANP32A acidic nuclear phosphoprotein 32 family member A ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr26:14,650,600...14,691,108
Ensembl chr26:14,653,745...14,691,492 		JBrowse link
G ANXA1 annexin A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr12:84,207,818...84,226,438
Ensembl chr12:84,207,820...84,226,562 		JBrowse link
G ANXA5 annexin A5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr 7:68,940,365...68,970,324
Ensembl chr 7:68,940,304...68,970,811 		JBrowse link
G APC APC regulator of WNT signaling pathway ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:1316610 PMID:1338764 PMID:2281069 PMID:8187091 PMID:8381579 More... NCBI chr23:15,992,437...16,135,117
Ensembl chr23:16,042,287...16,137,067 		JBrowse link
G APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr29:20,978,878...20,981,393 JBrowse link
G APOA1 apolipoprotein A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr 1:108,201,967...108,203,902
Ensembl chr 1:108,201,439...108,203,609 		JBrowse link
G APOBEC3B apolipoprotein B mRNA editing enzyme catalytic subunit 3B ISO CTD Direct Evidence: marker/mechanism CTD PMID:23852168
G APOC3 apolipoprotein C3 ISO protein:altered glycosylation:: RGD PMID:19322776 RGD:153344619 NCBI chr 1:108,196,283...108,199,274
Ensembl chr 1:108,196,939...108,199,342 		JBrowse link
G AQP4 aquaporin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr18:53,729,143...53,742,916
Ensembl chr18:53,729,186...53,743,156 		JBrowse link
G ARG1 arginase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr13:41,971,955...41,983,372
Ensembl chr13:41,971,802...41,983,049 		JBrowse link
G ARHGAP35 Rho GTPase activating protein 35 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr 6:40,264,466...40,353,157
Ensembl chr 6:40,205,892...40,353,280 		JBrowse link
G ARHGAP44 Rho GTPase activating protein 44 ISO mRNA:decreased expression:lung (human) RGD PMID:28527113 RGD:401901290 NCBI chr16:12,125,543...12,328,203
Ensembl chr16:12,125,574...12,330,501 		JBrowse link
G ATP5PD ATP synthase peripheral stalk subunit d ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr16:46,625,512...46,630,613 JBrowse link
G ATRX ATRX chromatin remodeler disease_progression ISO RGD PMID:31374064 RGD:127285382 NCBI chr  X:66,449,830...66,737,220
Ensembl chr  X:66,448,449...66,737,164 		JBrowse link
G AXIN2 axin 2 susceptibility
disease_progression		 ISO DNA:SNP:cds:p.P50S(human)
DNA:SNPs::1712 +19 G>A,148 C>T(human)		 RGD PMID:16820935 PMID:30346805 RGD:151356655 RGD:151356657 NCBI chr16:55,874,043...55,906,739
Ensembl chr16:55,874,072...55,907,281 		JBrowse link
G AZGP1 alpha-2-glycoprotein 1, zinc-binding ISO mRNA,protein:increased expression:lung RGD PMID:17724461 RGD:153350134 NCBI chr28:13,104,262...13,120,329
Ensembl chr28:13,104,323...13,120,363 		JBrowse link
G B2M beta-2-microglobulin ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:26619011 NCBI chr26:38,331,818...38,338,785
Ensembl chr26:38,331,442...38,338,809 		JBrowse link
G BAP1 BRCA1 associated deubiquitinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231345 NCBI chr22:13,765,510...13,774,866
Ensembl chr22:13,764,686...13,774,740 		JBrowse link
G BHLHE41 basic helix-loop-helix family member e41 ISO mRNA:decreased expression:lung (human) RGD PMID:18223678 RGD:151665316 NCBI chr11:25,872,139...25,879,985
Ensembl chr11:25,874,108...25,876,826 		JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 exacerbates ISO mRNA:increased expression:B cell (human) RGD PMID:33098370 RGD:153323293 NCBI chr 1:93,692,239...93,711,905 JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 disease_progression
ameliorates		 ISO mRNA:increased expression:lung (human) RGD PMID:31964418 RGD:153344516 NCBI chr16:70,226,824...70,237,000 JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:12068308 PMID:12198537 PMID:12447372 PMID:12460918 PMID:12460919 More... NCBI chr21:109,495,525...109,690,261 JBrowse link
G BTK Bruton tyrosine kinase exacerbates
susceptibility		 ISO mRNA:decreased expression:lung (human) RGD PMID:31803536 PMID:32351880 RGD:151347848 RGD:151347849 NCBI chr  X:89,690,569...89,727,420 JBrowse link
G BZW2 basic leucine zipper and W2 domains 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr21:41,409,358...41,469,833
Ensembl chr21:41,409,364...41,469,662 		JBrowse link
G CADM1 cell adhesion molecule 1 ISO DNA, mRNA:hypermethylation, decreased expression:promoter:liver RGD PMID:16814249 RGD:2289096 NCBI chr 1:106,539,262...106,876,397
Ensembl chr 1:106,539,136...106,606,637 		JBrowse link
G CALR calreticulin treatment ISO human cells and recombinant gene in a mouse model RGD PMID:18245558 RGD:150521698 NCBI chr 6:11,618,691...11,624,299
Ensembl chr 6:11,618,396...11,623,792 		JBrowse link
G CBX5 chromobox 5 disease_progression ISO mRNA,protein:increased expression:lung: RGD PMID:22900142 RGD:9586743 NCBI chr11:50,350,440...50,396,595
Ensembl chr11:50,353,638...50,396,608 		JBrowse link
G CBX7 chromobox 7 ISO mRNA,DNA:decreased expression, loss of heterozygosity:lung: RGD PMID:22214847 RGD:9587356 NCBI chr19:21,776,618...21,798,525
Ensembl chr19:21,775,931...21,798,309 		JBrowse link
G CCND1 cyclin D1 treatment
disease_progression		 ISO RGD PMID:19355812 PMID:26681199 RGD:11536846 RGD:13434927 NCBI chr 1:4,909,616...4,922,272
Ensembl chr 1:4,907,353...4,922,357 		JBrowse link
G CCND2 cyclin D2 disease_progression ISO RGD PMID:30308939 RGD:151665105 NCBI chr11:4,307,419...4,339,003
Ensembl chr11:4,307,401...4,333,661 		JBrowse link
G CCT5 chaperonin containing TCP1 subunit 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 4:9,787,093...9,802,892
Ensembl chr 4:9,787,101...9,805,852 		JBrowse link
G CD163 CD163 molecule ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr11:7,501,562...7,536,332
Ensembl chr11:7,501,150...7,536,295 		JBrowse link
G CD44 CD44 molecule (IN blood group) disease_progression ISO mRNA:increased expression:lung (human)
mRNA:splice variants:lung		 RGD PMID:18091389 PMID:29537891 RGD:149735539 RGD:2289345 NCBI chr 1:30,039,854...30,132,646
Ensembl chr 1:30,039,749...30,132,416 		JBrowse link
G CDC73 cell division cycle 73 exacerbates ISO mRNA:decreased expression:lung (human) RGD PMID:21692036 RGD:150537041 NCBI chr25:36,167,482...36,302,918
Ensembl chr25:36,170,134...36,302,812 		JBrowse link
G CDK12 cyclin dependent kinase 12 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar NCBI chr16:66,612,238...66,709,437
Ensembl chr16:66,623,785...66,708,755 		JBrowse link
G CDK4 cyclin dependent kinase 4 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:5377176 PMID:7652577 PMID:8528263 PMID:8968104 PMID:9228064 More... NCBI chr11:53,661,877...53,665,688
Ensembl chr11:53,659,336...53,664,861 		JBrowse link
G CDK6 cyclin dependent kinase 6 ISO protein:increased expression:lung RGD PMID:10574260 RGD:13464325 NCBI chr21:56,167,731...56,403,976
Ensembl chr21:56,170,450...56,393,808 		JBrowse link
G CHD4 chromodomain helicase DNA binding protein 4 susceptibility
ameliorates		 ISO mRNA:increased expression:lung (human)
DNA:missense mutation:CDS:p.D140E (rs7479004) (human)
human cells in a mouse model		 RGD PMID:28486105 PMID:29667179 PMID:32228507 RGD:151660359 RGD:153323299 RGD:153323307 NCBI chr11:6,603,820...6,641,278
Ensembl chr11:6,602,694...6,640,351 		JBrowse link
G CHRNA3 cholinergic receptor nicotinic alpha 3 subunit susceptibility ISO associated with smoking; DNA:SNP: :rs1051730(human)
ClinVar Annotator: match by term: Lung adenocarcinoma
DNA:SNP: :rs8042374(human)		 RGD
ClinVar		 PMID:20554942 PMID:24686516 PMID:27993330 RGD:150527848 RGD:151347530 NCBI chr26:4,721,145...4,747,694
Ensembl chr26:4,722,489...4,737,164 		JBrowse link
G CHRNA5 cholinergic receptor nicotinic alpha 5 subunit susceptibility
disease_progression		 ISO associated with smoking; DNA:SNPs: :rs2036527, rs684513, rs667282(human)
ClinVar Annotator: match by term: Lung adenocarcinoma
DNA:SNP:cds: p.D398N(human)
DNA:SNP: :rs503464(human)		 RGD
ClinVar		 PMID:19577767 PMID:20554942 PMID:23314339 PMID:27993330 RGD:150524359 RGD:150527848 RGD:150527849 NCBI chr26:4,747,734...4,779,231
Ensembl chr26:4,749,766...4,776,822 		JBrowse link
G CHRNB4 cholinergic receptor nicotinic beta 4 subunit ISO mRNA:increased expression:lung
DNA:hypomethylation:promoter:		 RGD PMID:20124469 PMID:22945651 RGD:150527851 RGD:151361154 NCBI chr26:4,700,217...4,717,363
Ensembl chr26:4,701,321...4,719,319 		JBrowse link
G CLPTM1L CLPTM1 like susceptibility
no_association
ameliorates		 ISO CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs401681(human)
DNA:SNP::rs77518573(human)
DNA:SNP:: rs4975616(human)
DNA:SNP::rs401681(human)
DNA:SNP:: rs31490(human)
mRNA:increased expression:lung		 CTD
RGD		 PMID:19955392 PMID:22675468 PMID:23738012 PMID:23908149 PMID:24366883 More... RGD:150530483 RGD:150530485 RGD:150530498 RGD:150530499 RGD:150530502 RGD:150530635 RGD:150537098 NCBI chr 4:1,140,272...1,162,663
Ensembl chr 4:1,140,132...1,162,898 		JBrowse link
G CMTR2 cap methyltransferase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr 5:54,428,889...54,435,770
Ensembl chr 5:54,430,197...54,432,509 		JBrowse link
G COL10A1 collagen type X alpha 1 chain disease_progression ISO mRNA:increased expression:lung RGD PMID:33324550 RGD:150429752 NCBI chr13:57,657,310...57,697,955
Ensembl chr13:57,691,409...57,696,783 		JBrowse link
G CREBBP CREB binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr 5:3,415,548...3,570,030
Ensembl chr 5:3,415,412...3,540,943 		JBrowse link
G CSF1R colony stimulating factor 1 receptor ISO protein:increased expression:lung (human) RGD PMID:23702648 RGD:150524280 NCBI chr23:52,663,290...52,723,652
Ensembl chr23:52,664,076...52,697,304 		JBrowse link
G CSRP3 cysteine and glycine rich protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:45,792,106...45,813,715
Ensembl chr 1:45,803,243...45,813,800 		JBrowse link
G CTNNB1 catenin beta 1 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:9065402 PMID:9065403 PMID:9294210 PMID:9500465 PMID:9927029 More... NCBI chr22:2,679,488...2,725,034
Ensembl chr22:2,684,022...2,723,949 		JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 exacerbates ISO protein:increased expression:lung (human)
mRNA:increased expression:lung (human)		 RGD PMID:19716197 PMID:30103827 RGD:152023735 RGD:152177480 NCBI chr10:20,336,470...20,340,308
Ensembl chr10:20,336,247...20,340,309 		JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 ISO protein:increased expression:lung (human) RGD PMID:19358281 RGD:152177688 NCBI chr14:69,318,713...69,327,277
Ensembl chr14:69,319,495...69,324,157 		JBrowse link
G CYP24A1 cytochrome P450 family 24 subfamily A member 1 ameliorates ISO DNA:hypomethylation:promoter (human)
mRNA:decreased expression:lung (human)
human cell line in a mouse model		 RGD PMID:24736069 PMID:25519225 PMID:27793774 RGD:151361181 RGD:151665173 RGD:151665499 NCBI chr 2:9,868,794...9,889,510
Ensembl chr 2:9,868,678...9,885,884 		JBrowse link
G DDR2 discoidin domain receptor tyrosine kinase 2 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr20:1,298,636...1,451,872
Ensembl chr20:1,299,574...1,359,674 		JBrowse link
G DLL4 delta like canonical Notch ligand 4 treatment ISO RGD PMID:33628824 RGD:155663482 NCBI chr26:42,056,473...42,066,283
Ensembl chr26:42,056,331...42,065,828 		JBrowse link
G DNMT3A DNA methyltransferase 3 alpha ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:21067377 PMID:21518476 PMID:22160010 PMID:22722925 PMID:22744846 More... NCBI chr14:82,313,414...82,427,170
Ensembl chr14:82,402,826...82,420,819 		JBrowse link
G DNMT3B DNA methyltransferase 3 beta susceptibility ISO DNA:SNPs,haplotype:promoter:-283T >C,-579G>T(human) RGD PMID:15528220 RGD:9589086 NCBI chr 2:37,128,635...37,176,033
Ensembl chr 2:37,146,538...37,174,570 		JBrowse link
G DOK1 docking protein 1 disease_progression ISO RGD PMID:20139980 RGD:152177521 NCBI chr14:32,720,237...32,723,578
Ensembl chr14:32,720,026...32,723,286 		JBrowse link
G DOK2 docking protein 2 exacerbates
disease_progression		 ISO mRNA:decreased expression:lung (human) RGD PMID:20139980 PMID:24255704 PMID:30475228 RGD:152177492 RGD:152177493 RGD:152177521 NCBI chr 8:19,979,303...19,984,022
Ensembl chr 8:19,979,298...19,984,263 		JBrowse link
G DOK3 docking protein 3 disease_progression ISO RGD PMID:20139980 RGD:152177521 NCBI chr23:79,514,800...79,522,176
Ensembl chr23:79,515,025...79,520,557 		JBrowse link
G DOT1L DOT1 like histone lysine methyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr 6:1,962,077...2,030,732
Ensembl chr 6:1,962,279...2,026,455 		JBrowse link
G E2F1 E2F transcription factor 1 ISO mRNA:increased expression:lung RGD PMID:26695082 RGD:13464334 NCBI chr 2:37,968,541...37,980,461
Ensembl chr 2:37,968,556...37,980,326 		JBrowse link
G E2F3 E2F transcription factor 3 ISO RGD PMID:16938365 RGD:13464341 NCBI chr17:51,714,052...51,805,827 JBrowse link
G EEF2 eukaryotic translation elongation factor 2 exacerbates ISO protein:increased expression:lung (human) RGD PMID:21554491 RGD:153298904 NCBI chr 6:3,733,056...3,742,526
Ensembl chr 6:3,732,425...3,742,826 		JBrowse link
G EEF2K eukaryotic elongation factor 2 kinase ameliorates ISO Human cells in mouse model RGD PMID:30522114 RGD:153298964 NCBI chr 5:19,871,669...19,957,471
Ensembl chr 5:19,871,310...19,957,395 		JBrowse link
G EGF epidermal growth factor ISO DNA:polymorphism: :p.A61G (human) RGD PMID:26625757 RGD:11538684 NCBI chr 7:57,810,110...57,911,361
Ensembl chr 7:57,811,728...57,911,516 		JBrowse link
G EGFR epidermal growth factor receptor disease_progression ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Adenocarcinoma of lung, somatic | ClinVar Annotator: match by term: Lung adenocarcinoma RGD
ClinVar		 PMID:2302402 PMID:11423618 PMID:15118073 PMID:15118125 PMID:15272417 More... RGD:126790475 NCBI chr21:3,664,622...3,853,492
Ensembl chr21:3,666,339...3,853,239 		JBrowse link
G EHMT2 euchromatic histone lysine methyltransferase 2 disease_progression ISO RGD PMID:20940408 RGD:9589170 NCBI chr17:40,123,935...40,141,942
Ensembl chr17:40,124,640...40,141,616 		JBrowse link
G EIF2B1 eukaryotic translation initiation factor 2B subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr11:118,949,674...118,961,913
Ensembl chr11:118,950,409...118,961,687 		JBrowse link
G EIF2B4 eukaryotic translation initiation factor 2B subunit delta ISO CTD Direct Evidence: marker/mechanism CTD PMID:24366584 NCBI chr14:80,240,874...80,247,555
Ensembl chr14:80,240,449...80,249,521 		JBrowse link
G EIF2B5 eukaryotic translation initiation factor 2B subunit epsilon ISO CTD Direct Evidence: marker/mechanism CTD PMID:24366584 NCBI chr15:5,278,759...5,289,422
Ensembl chr15:5,278,749...5,289,030 		JBrowse link
G EIF3E eukaryotic translation initiation factor 3 subunit E ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 8:102,915,111...102,960,669
Ensembl chr 8:102,915,252...102,960,559 		JBrowse link
G EML4 EMAP like 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22980554 PMID:22999080 NCBI chr14:64,927,288...65,090,904
Ensembl chr14:64,929,617...65,090,861 		JBrowse link
G EMX2 empty spiracles homeobox 2 exacerbates ISO mRNA,protein:decreased expression:lung (human) RGD PMID:21726823 RGD:153323303 NCBI chr 9:110,347,043...110,353,647
Ensembl chr 9:110,347,379...110,353,643 		JBrowse link
G ENO1 enolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 PMID:27602772 NCBI chr20:122,884,846...122,902,669
Ensembl chr20:122,884,727...122,903,372 		JBrowse link
G EP300 E1A binding protein p300 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr19:23,634,132...23,726,095
Ensembl chr19:23,634,571...23,724,979 		JBrowse link
G EPHA5 EPH receptor A5 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:16140923 NCBI chr 7:3,219,396...3,564,416
Ensembl chr 7:3,219,449...3,559,854 		JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 disease_progression ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma RGD
ClinVar		 PMID:15457249 PMID:15753357 PMID:16638863 PMID:18334834 PMID:22325357 More... RGD:126790475 NCBI chr16:66,435,488...66,464,993
Ensembl chr16:66,434,251...66,464,952 		JBrowse link
G ERBB3 erb-b2 receptor tyrosine kinase 3 disease_progression ISO RGD PMID:26824984 RGD:126790475 NCBI chr11:52,020,912...52,043,809
Ensembl chr11:52,021,058...52,044,028 		JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 disease_progression ISO RGD PMID:26824984 RGD:126790475 NCBI chr10:97,099,090...98,281,697 JBrowse link
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:21327329 NCBI chr 6:38,857,067...38,900,177
Ensembl chr 6:38,854,803...38,872,967 		JBrowse link
G ERCC6L ERCC excision repair 6 like, spindle assembly checkpoint helicase exacerbates ISO mRNA:increased expression:lung (human) RGD PMID:35150321 RGD:155260359 NCBI chr  X:62,013,003...62,061,669 JBrowse link
G ERGIC3 ERGIC and golgi 3 disease_progression
ameliorates		 ISO mRNA,protein:increased expression:lung (human) RGD PMID:23374247 PMID:27588471 RGD:151708716 RGD:153323314 NCBI chr 2:56,474,811...56,482,788 JBrowse link
G ERP29 endoplasmic reticulum protein 29 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr11:107,244,359...107,255,293
Ensembl chr11:107,244,335...107,256,499 		JBrowse link
G ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2 ameliorates ISO RGD PMID:33573689 RGD:155791670 NCBI chr 8:25,885,823...25,919,863
Ensembl chr 8:25,887,309...25,916,630 		JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit disease_progression ISO RGD PMID:24097870 RGD:126781716 NCBI chr21:117,380,518...117,515,224
Ensembl chr21:117,380,361...117,421,573 		JBrowse link
G FASN fatty acid synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr16:73,988,410...74,008,374
Ensembl chr16:73,982,899...74,006,551 		JBrowse link
G FBL fibrillarin ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 6:34,370,558...34,382,909
Ensembl chr 6:34,370,558...34,376,836 		JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung ClinVar PMID:26619011 NCBI chr 7:98,894,261...99,105,955
Ensembl chr 7:98,892,504...99,106,084 		JBrowse link
G FES FES proto-oncogene, tyrosine kinase treatment ISO human cells in a mouse model RGD PMID:31573955 RGD:153323295 NCBI chr29:8,967,542...8,979,475
Ensembl chr29:8,965,997...8,979,361 		JBrowse link
G FGF10 fibroblast growth factor 10 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr 4:43,080,387...43,163,355
Ensembl chr 4:43,081,831...43,163,432 		JBrowse link
G FGF18 fibroblast growth factor 18 ISO mRNA:decreased expression:lung (human) RGD PMID:19296538 RGD:150429981 NCBI chr23:73,584,223...73,620,881
Ensembl chr23:73,584,766...73,620,069 		JBrowse link
G FGF9 fibroblast growth factor 9 disease_progression ISO protein:increased expression:lung (human)
mRNA:decreased expression:lung (human)		 RGD PMID:19296538 PMID:19358281 PMID:20464547 RGD:150429981 RGD:152177688 RGD:152975620 NCBI chr 3:1,779,126...1,811,427
Ensembl chr 3:1,779,192...1,812,784 		JBrowse link
G FGFR2 fibroblast growth factor receptor 2 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:17525745 PMID:18552176 PMID:22238366 PMID:23002168 PMID:23908597 More... NCBI chr 9:114,234,344...114,354,736
Ensembl chr 9:114,234,250...114,354,704 		JBrowse link
G FGFR3 fibroblast growth factor receptor 3 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung ClinVar PMID:1908846 PMID:7773297 PMID:8640234 PMID:8858131 PMID:9438390 More... NCBI chr27:46,958,444...46,974,032
Ensembl chr27:46,957,254...46,973,392 		JBrowse link
G FGFR4 fibroblast growth factor receptor 4 disease_progression
exacerbates		 ISO DNA:SNP:exon 9: p.G388R (human)
DNA:SNP:exon 9: p.G388R (rs351855)(human)
human cells in mouse model		 RGD PMID:16061909 PMID:19296538 PMID:29402970 RGD:150429976 RGD:150429981 RGD:150429984 NCBI chr23:79,095,031...79,106,018
Ensembl chr23:79,097,429...79,105,456 		JBrowse link
G FKBP11 FKBP prolyl isomerase 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr11:45,155,157...45,158,973
Ensembl chr11:45,154,026...45,158,628 		JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr 3:7,412,506...7,608,122
Ensembl chr 3:7,412,172...7,607,967 		JBrowse link
G FOXA1 forkhead box A1 ISO mRNA:increased expression:lung
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:12234996 PMID:29072684 PMID:34254728 RGD:151665758 RGD:151665822 NCBI chr24:14,397,759...14,403,078
Ensembl chr24:14,396,702...14,403,094 		JBrowse link
G FOXO3 forkhead box O3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19380174 NCBI chr13:65,175,764...65,303,107
Ensembl chr13:65,195,376...65,301,725 		JBrowse link
G FOXP1 forkhead box P1 ISO mRNA:decreased expression:lung (rat) RGD PMID:16023287 RGD:11561933 NCBI chr22:31,907,941...32,538,294
Ensembl chr22:31,912,460...32,154,502 		JBrowse link
G FOXP2 forkhead box P2 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr21:82,799,147...83,392,568
Ensembl chr21:83,129,308...83,389,483 		JBrowse link
G FOXP4 forkhead box P4 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr17:30,554,702...30,608,845
Ensembl chr17:30,554,055...30,589,849 		JBrowse link
G FPR2 formyl peptide receptor 2 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr 6:44,580,342...44,591,187
Ensembl chr 6:44,589,334...44,590,389 		JBrowse link
G FRZB frizzled related protein severity ISO mRNA:decreased expression:lung (human) RGD PMID:27623992 RGD:32716395 NCBI chr10:68,353,393...68,385,135
Ensembl chr10:68,351,922...68,385,110 		JBrowse link
G FUBP1 far upstream element binding protein 1 ISO mRNA:decreased expression:lung (human) RGD PMID:32481602 RGD:151361197 NCBI chr20:55,194,681...55,233,666
Ensembl chr20:55,194,743...55,230,277 		JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr11:6,569,029...6,572,877 JBrowse link
G GAR1 GAR1 ribonucleoprotein ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 7:57,713,245...57,722,831
Ensembl chr 7:57,713,881...57,722,224 		JBrowse link
G GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 2:58,641,566...58,682,014
Ensembl chr 2:58,643,877...58,683,023 		JBrowse link
G GJB2 gap junction protein beta 2 ISO DNA, mRNA:hypermethylation, decreased expression:lung RGD PMID:16637067 RGD:11568669 NCBI chr 3:801,786...808,165
Ensembl chr 3:807,379...808,059 		JBrowse link
G GNPNAT1 glucosamine-phosphate N-acetyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr24:29,862,903...29,878,050
Ensembl chr24:29,863,956...29,878,135 		JBrowse link
G GOLM1 golgi membrane protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr12:96,706,865...96,778,687
Ensembl chr12:96,708,548...96,779,065 		JBrowse link
G GPI glucose-6-phosphate isomerase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 6:29,404,067...29,451,290
Ensembl chr 6:29,403,500...29,453,162 		JBrowse link
G GPX3 glutathione peroxidase 3 ISO mRNA:decreased expression:lung (human) RGD PMID:23374247 RGD:151708716 NCBI chr23:53,576,950...53,585,321 JBrowse link
G GRWD1 glutamate rich WD repeat containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 6:41,707,669...41,715,293
Ensembl chr 6:41,707,743...41,714,425 		JBrowse link
G H1FX H1 histone family member X ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr22:51,749,560...51,751,081
Ensembl chr22:51,749,948...51,750,586 		JBrowse link
G HELLS helicase, lymphoid specific ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 9:87,780,897...87,835,087
Ensembl chr 9:87,796,502...87,834,619 		JBrowse link
G HK1 hexokinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 9:61,917,501...62,029,737
Ensembl chr 9:61,917,440...62,001,843 		JBrowse link
G HK2 hexokinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr14:32,385,237...32,443,864
Ensembl chr14:32,385,249...32,442,403 		JBrowse link
G HMGB2 high mobility group box 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24366584 PMID:27602772 NCBI chr 7:119,440,089...119,442,806
Ensembl chr 7:119,440,468...119,443,578 		JBrowse link
G HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr11:50,397,173...50,403,192
Ensembl chr11:50,396,888...50,400,802 		JBrowse link
G HOXB7 homeobox B7 severity ISO protein:increased expression:lung epithelium (human) RGD PMID:22911672 RGD:10402176 NCBI chr16:69,020,325...69,024,362
Ensembl chr16:69,020,906...69,023,671 		JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:1904555 PMID:3510078 PMID:11150980 PMID:12835555 PMID:16155195 More... NCBI chr 1:343,613...345,782
Ensembl chr 1:343,506...346,637 		JBrowse link
G HSD17B10 hydroxysteroid 17-beta dehydrogenase 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr  X:49,568,206...49,571,356
Ensembl chr  X:49,567,267...49,571,292 		JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 ISO mRNA:increased expression:lung (human) RGD PMID:23374247 RGD:151708716 NCBI chr11:99,119,268...99,139,988
Ensembl chr11:99,119,224...99,139,722 		JBrowse link
G HSPB1 heat shock protein family B (small) member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr28:10,442,530...10,443,804
Ensembl chr28:10,442,398...10,443,855 		JBrowse link
G HTR4 5-hydroxytryptamine receptor 4 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr23:51,087,430...51,279,915
Ensembl chr23:51,087,285...51,182,200 		JBrowse link
G HTRA1 HtrA serine peptidase 1 disease_progression ISO human cells in mouse model RGD PMID:24356998 RGD:152975621 NCBI chr 9:115,197,543...115,250,092
Ensembl chr 9:115,197,566...115,253,919 		JBrowse link
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 disease_progression ISO protein:increased expression:blood plasma (human)
ClinVar Annotator: match by term: Adenocarcinoma of lung
mRNA:increased expression:lung (human)		 RGD
ClinVar		 PMID:18772396 PMID:19657110 PMID:19798509 PMID:19818334 PMID:20946881 More... RGD:149735539 RGD:149735540 NCBI chr10:94,021,002...94,039,997
Ensembl chr10:94,020,818...94,039,975 		JBrowse link
G IGF2R insulin like growth factor 2 receptor ISO mRNA:deletions: :c.3698_4902del, c.3366_4902del, c.3817_4697del (rat) RGD PMID:12503077 RGD:1298968 NCBI chr13:87,587,717...87,723,795
Ensembl chr13:87,587,907...87,724,116 		JBrowse link
G IKZF1 IKAROS family zinc finger 1 exacerbates
ameliorates		 ISO protein:increased expression:lung (human)
mRNA:increased expression:lung (human)		 RGD PMID:32787735 PMID:33738286 RGD:150540324 RGD:151347632 NCBI chr21:8,398,902...8,500,431
Ensembl chr21:8,402,719...8,484,723 		JBrowse link
G IL1R2 interleukin 1 receptor type 2 disease_progression
severity		 ISO mRNA:altered expression:lung (human)
mRNA:increased expression:lung (human)		 RGD PMID:29942094 PMID:31921619 RGD:152998982 RGD:152998998 NCBI chr14:5,672,434...5,708,270
Ensembl chr14:5,673,163...5,708,372 		JBrowse link
G IMPDH2 inosine monophosphate dehydrogenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr22:10,424,646...10,429,917
Ensembl chr22:10,421,996...10,429,662 		JBrowse link
G IPO4 importin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr24:1,165,892...1,174,660
Ensembl chr24:1,162,219...1,174,487 		JBrowse link
G IPO5 importin 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 3:76,644,113...76,690,718
Ensembl chr 3:76,644,131...76,692,146 		JBrowse link
G IQSEC1 IQ motif and Sec7 domain ArfGEF 1 disease_progression ISO RGD PMID:24902879 RGD:153350085 NCBI chr22:48,873,240...49,050,666
Ensembl chr22:48,872,925...49,050,625 		JBrowse link
G IRAK3 interleukin 1 receptor associated kinase 3 ISO mRNA:increased expression:lung (human) RGD PMID:21278795 RGD:36049796 NCBI chr11:61,868,817...61,920,896
Ensembl chr11:61,869,173...61,920,406 		JBrowse link
G IREB2 iron responsive element binding protein 2 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr26:4,842,328...4,905,941
Ensembl chr26:4,842,122...4,905,964 		JBrowse link
G JAK2 Janus kinase 2 treatment ISO human cells in mouse model RGD PMID:27025877 RGD:11574134 NCBI chr12:74,421,243...74,566,766
Ensembl chr12:74,421,016...74,566,710 		JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:24366584 NCBI chr 6:11,479,108...11,480,942
Ensembl chr 6:11,479,407...11,480,450 		JBrowse link
G KCNJ4 potassium inwardly rectifying channel subfamily J member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30512237 NCBI chr19:21,085,857...21,114,961
Ensembl chr19:21,086,322...21,087,659 		JBrowse link
G KLF5 KLF transcription factor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr 3:52,188,139...52,210,882 JBrowse link
G KMT2C lysine methyltransferase 2C onset
disease_progression		 ISO RGD PMID:30821106 PMID:32867667 RGD:151356760 RGD:151356761 NCBI chr21:120,299,295...120,587,843
Ensembl chr21:120,301,188...120,587,137 		JBrowse link
G KPNA2 karyopherin subunit alpha 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr16:53,422,792...53,434,693
Ensembl chr16:53,423,040...53,433,290 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Adenocarcinoma of lung
ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma		 ClinVar PMID:2278970 PMID:3122217 PMID:6320174 PMID:11745231 PMID:12460918 More... NCBI chr11:24,963,396...25,010,747
Ensembl chr11:24,973,619...25,005,191 		JBrowse link
G LDHA lactate dehydrogenase A ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:46,525,090...46,542,587 JBrowse link
G LECT2 leukocyte cell derived chemotaxin 2 ameliorates ISO human cells in mouse model RGD PMID:30453282 RGD:153323337 NCBI chr23:38,696,216...38,705,530
Ensembl chr23:38,696,203...38,705,087 		JBrowse link
G LMNA lamin A/C ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr20:7,723,059...7,748,799
Ensembl chr20:7,723,477...7,748,780 		JBrowse link
G LMNB1 lamin B1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr23:29,759,133...29,814,332
Ensembl chr23:29,759,514...29,814,314 		JBrowse link
G LOC103219498 RNA 3'-terminal phosphate cyclase-like protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr12:74,688,284...74,754,184
Ensembl chr12:74,687,071...74,754,045 		JBrowse link
G LOC103219520 splicing factor U2AF 35 kDa subunit-like protein ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:22158538 PMID:23029227 PMID:23861105 PMID:24498085 PMID:26619011 NCBI chr 2:86,949,910...86,964,655
Ensembl chr 2:86,950,056...86,964,579 		JBrowse link
G LOC103219825 protein patched homolog 1 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 PMID:28492532 NCBI chr12:107,580,895...107,656,443
Ensembl chr12:107,590,663...107,652,985 		JBrowse link
G LOC103219957 macrophage-capping protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr14:21,742,163...21,761,462
Ensembl chr14:21,746,044...21,761,322 		JBrowse link
G LOC103231165 isocitrate dehydrogenase (NADP(+)) 2 severity ISO protein:increased expression:lung (human)
protein:increased expression:blood serum (human)		 RGD PMID:29465809 PMID:30128035 RGD:149735564 RGD:149735567 NCBI chr29:8,633,429...8,650,744
Ensembl chr29:8,633,715...8,650,657 		JBrowse link
G LOC103231895 serine/threonine-protein kinase A-Raf ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:24569458 PMID:26619011 NCBI chr  X:44,738,406...44,748,996
Ensembl chr  X:44,740,181...44,748,550 		JBrowse link
G LOC103232362 60S ribosomal protein L36a ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr  X:89,731,684...89,736,393
Ensembl chr  X:89,731,725...89,736,338 		JBrowse link
G LOC103233229 cadherin-1 ISO DNA:increased methylation RGD PMID:16329148 RGD:1599556 NCBI chr 5:58,578,244...58,679,677
Ensembl chr 5:58,578,146...58,679,541 		JBrowse link
G LOC103242066 mucin-4 disease_progression ISO protein:increased expression:trachea RGD PMID:17126950 RGD:5131208 NCBI chr15:91,313,060...91,345,172 JBrowse link
G LOC103243509 neuroendocrine secretory protein 55 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung ClinVar PMID:1517386 PMID:1594625 PMID:1944469 PMID:2549426 PMID:3720010 More... NCBI chr 2:5,233,893...5,303,433
Ensembl chr 2:5,233,874...5,249,192 		JBrowse link
G LRP1B LDL receptor related protein 1B disease_progression ISO DNA:mutations:multiple: (human) RGD PMID:18948947 RGD:11064706 NCBI chr10:25,611,400...27,511,903
Ensembl chr10:25,616,590...26,609,111 		JBrowse link
G LRRC56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:1904555 PMID:3510078 PMID:11150980 PMID:12835555 PMID:16155195 More... NCBI chr 1:352,131...370,276
Ensembl chr 1:355,982...369,633 		JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:18632602 PMID:21383288 PMID:22197931 PMID:22588879 PMID:23444215 More... NCBI chr26:17,059,122...17,168,787
Ensembl chr26:17,060,054...17,168,782 		JBrowse link
G MAP2K4 mitogen-activated protein kinase kinase 4 severity ISO RGD PMID:12231543 PMID:21896780 RGD:150429783 RGD:150429821 NCBI chr16:11,366,610...11,485,411
Ensembl chr16:11,366,751...11,486,125 		JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 exacerbates ISO human gene in a mouse model RGD PMID:34236045 RGD:155230828 NCBI chr 6:7,355,387...7,365,944
Ensembl chr 6:7,355,434...7,364,398 		JBrowse link
G MAP3K8 mitogen-activated protein kinase kinase kinase 8 exacerbates ISO RGD PMID:23533274 RGD:151356978
G MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 ameliorates
exacerbates		 ISO protein:increased expression:lung (human)
human cell line in a mouse model
mRNA, protein:increased expression:lung (human)		 RGD PMID:22824148 PMID:28306189 PMID:33510968 RGD:151347677 RGD:151347678 RGD:151347681 NCBI chr14:5,391,416...5,579,163
Ensembl chr14:5,391,449...5,583,916 		JBrowse link
G MAPK14 mitogen-activated protein kinase 14 exacerbates ISO mRNA:increased expression:lung (human) RGD PMID:31969449 RGD:151665505 NCBI chr17:36,012,164...36,095,542
Ensembl chr17:36,014,454...36,095,138 		JBrowse link
G MCL1 MCL1 apoptosis regulator, BCL2 family member treatment
severity		 ISO human cells in mouse model
mRNA:increased expression:lung (human)		 RGD PMID:31200834 RGD:151356911
G MEOX1 mesenchyme homeobox 1 ISO CTD Direct Evidence: therapeutic CTD PMID:34837450 NCBI chr16:62,747,031...62,770,711
Ensembl chr16:62,748,671...62,770,706 		JBrowse link
G MIER3 MIER family member 3 ameliorates ISO RGD PMID:35117188 RGD:407571696 NCBI chr 4:53,144,256...53,177,429
Ensembl chr 4:53,147,773...53,172,089 		JBrowse link
G MKI67 marker of proliferation Ki-67 disease_progression ISO protein:altered expression:lung (human) RGD PMID:26942465 RGD:152999419 NCBI chr 9:120,697,183...120,727,039
Ensembl chr 9:120,698,834...120,726,866 		JBrowse link
G MLH1 mutL homolog 1 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:15340264 PMID:17510385 PMID:18307539 PMID:19419416 PMID:22136435 More... NCBI chr15:2,364,537...2,418,379
Ensembl chr15:2,364,738...2,418,393 		JBrowse link
G MRE11 MRE11 homolog, double strand break repair nuclease ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:85,615,448...85,694,247
Ensembl chr 1:85,610,819...85,694,269 		JBrowse link
G MRPL12 mitochondrial ribosomal protein L12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr16:73,633,786...73,639,142
Ensembl chr16:73,633,918...73,638,902 		JBrowse link
G MRPS5 mitochondrial ribosomal protein S5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr14:124,884...155,600 JBrowse link
G MS4A1 membrane spanning 4-domains A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22514692 NCBI chr 1:13,343,647...13,358,639
Ensembl chr 1:13,345,253...13,358,547 		JBrowse link
G MSH2 mutS homolog 2 no_association ISO DNA:polymorphisms:promoter, intron:-118T>C, IVS1+9G>C (human)
DNA:polymorphisms:introns:IVS10+12A>G, IVS12-6T>C (human)		 RGD PMID:16614121 RGD:11065547 NCBI chr14:59,730,101...59,802,857
Ensembl chr14:59,729,789...59,802,819 		JBrowse link
G MSH3 mutS homolog 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21327329 NCBI chr 4:74,811,181...75,032,067
Ensembl chr 4:74,811,198...75,032,005 		JBrowse link
G MSH6 mutS homolog 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21327329 NCBI chr14:59,375,602...59,400,252
Ensembl chr14:59,375,691...59,400,174 		JBrowse link
G MUC1 mucin 1, cell surface associated ISO mRNA:increased expression:lung RGD PMID:8694545 RGD:5131260 NCBI chr20:8,641,701...8,646,739
Ensembl chr20:8,642,842...8,646,962 		JBrowse link
G MUC5AC mucin 5AC, oligomeric mucus/gel-forming ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr 1:981,515...1,018,242 JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:25157968 PMID:26619011 NCBI chr 8:122,282,989...122,288,392
Ensembl chr 8:122,282,630...122,288,384 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor treatment
ameliorates		 ISO mouse cell line in a mouse model RGD PMID:30712876 PMID:32140881 RGD:150520172 RGD:150540309 NCBI chr15:1,276,804...1,281,811
Ensembl chr15:1,276,798...1,281,166 		JBrowse link
G NAA10 N-alpha-acetyltransferase 10, NatA catalytic subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr  X:128,353,262...128,359,222
Ensembl chr  X:128,352,634...128,359,085 		JBrowse link
G NAIP NLR family apoptosis inhibitory protein ameliorates ISO mRNA:increased expression:lung (human) RGD PMID:31964418 RGD:153344516 NCBI chr 4:65,693,044...65,742,527 JBrowse link
G NCAPG non-SMC condensin I complex subunit G ISO CTD Direct Evidence: marker/mechanism CTD PMID:34419073 NCBI chr27:32,380,722...32,413,659
Ensembl chr27:32,377,575...32,413,494 		JBrowse link
G NCL nucleolin ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr10:117,478,279...117,487,810 JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:26619011 PMID:29018201 NCBI chr10:62,789,647...62,825,651
Ensembl chr10:62,790,124...62,825,339 		JBrowse link
G NKX2-1 NK2 homeobox 1 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr24:13,274,118...13,317,533
Ensembl chr24:13,310,846...13,317,056 		JBrowse link
G NLRP3 NLR family pyrin domain containing 3 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr25:84,431,436...84,463,387
Ensembl chr25:84,434,527...84,463,249 		JBrowse link
G NOP56 NOP56 ribonucleoprotein ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 2:53,882,070...53,887,867
Ensembl chr 2:53,882,169...53,887,565 		JBrowse link
G NOP58 NOP58 ribonucleoprotein ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr10:87,989,687...88,026,774
Ensembl chr10:87,989,699...88,026,904 		JBrowse link
G NOTCH1 notch receptor 1 treatment ISO RGD PMID:33628824 RGD:155663482 NCBI chr12:1,656,815...1,707,566
Ensembl chr12:1,656,918...1,709,585 		JBrowse link
G NPM1 nucleophosmin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr23:73,555,020...73,575,910
Ensembl chr23:73,555,260...73,575,925 		JBrowse link
G NPM3 nucleophosmin/nucleoplasmin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 9:94,809,050...94,811,169
Ensembl chr 9:94,809,468...94,811,091 		JBrowse link
G NRAS NRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Adenocarcinoma of lung ClinVar PMID:1654209 PMID:2278970 PMID:2674680 PMID:3122217 PMID:6587382 More... NCBI chr20:18,953,273...18,966,002
Ensembl chr20:18,953,883...18,961,931 		JBrowse link
G NUDT21 nudix hydrolase 21 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 5:42,340,717...42,360,844
Ensembl chr 5:42,337,873...42,360,817 		JBrowse link
G NUF2 NUF2 component of NDC80 kinetochore complex disease_progression ISO RGD PMID:32226507 RGD:28912743 NCBI chr25:65,462,608...65,493,242
Ensembl chr25:65,462,603...65,493,246 		JBrowse link
G OGG1 8-oxoguanine DNA glycosylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23951099 NCBI chr22:45,757,414...45,763,690 JBrowse link
G PABPC4 poly(A) binding protein cytoplasmic 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr20:93,161,868...93,177,863
Ensembl chr20:93,161,877...93,177,839 		JBrowse link
G PACRG parkin coregulated ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:12719539 NCBI chr13:90,329,583...90,937,143 JBrowse link
G PCBD1 pterin-4 alpha-carbinolamine dehydratase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 9:60,417,301...60,422,313 JBrowse link
G PIGN phosphatidylinositol glycan anchor biosynthesis class N ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr18:17,589,582...17,725,823
Ensembl chr18:17,589,631...17,725,823 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More... NCBI chr15:10,218,034...10,304,874
Ensembl chr15:10,218,805...10,294,316 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO mRNA:decreased expression:lung RGD PMID:26695082 RGD:13464334 NCBI chr 4:64,321,296...64,406,188
Ensembl chr 4:64,321,078...64,406,519 		JBrowse link
G PITX2 paired like homeodomain 2 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr 7:58,501,669...58,526,413
Ensembl chr 7:58,501,559...58,507,318 		JBrowse link
G PLCG1 phospholipase C gamma 1 exacerbates ISO protein:decreased expression:lung (human) RGD PMID:33077911 RGD:151356960 NCBI chr 2:22,599,547...22,638,394 JBrowse link
G PLOD2 procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 disease_progression ISO RGD PMID:29072684 RGD:151665822 NCBI chr15:44,489,804...44,590,284
Ensembl chr15:44,490,042...44,591,526 		JBrowse link
G POLR1D RNA polymerase I and III subunit D ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 3:6,773,426...6,819,045 JBrowse link
G PPAN peter pan homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 6:9,174,978...9,180,121
Ensembl chr 6:9,174,990...9,179,990 		JBrowse link
G PPP2R1A protein phosphatase 2 scaffold subunit Aalpha ISO ClinVar Annotator: match by term: Adenocarcinoma of lung ClinVar PMID:25741868 PMID:26168268 PMID:26619011 PMID:28492532 PMID:31687265 More... NCBI chr 6:44,990,402...45,026,210
Ensembl chr 6:44,990,367...45,026,227 		JBrowse link
G PPP3CA protein phosphatase 3 catalytic subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr 7:49,149,044...49,478,796
Ensembl chr 7:49,148,933...49,321,013 		JBrowse link
G PRDM1 PR/SET domain 1 exacerbates ISO RGD PMID:28378641 RGD:150530469 NCBI chr13:67,695,436...67,719,487
Ensembl chr13:67,695,309...67,718,931 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:12719539 NCBI chr13:88,856,056...90,329,379 JBrowse link
G PSAT1 phosphoserine aminotransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr12:89,223,463...89,256,017
Ensembl chr12:89,223,526...89,256,022 		JBrowse link
G PTEN phosphatase and tensin homolog ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr 9:81,308,058...81,412,386
Ensembl chr 9:81,309,099...81,409,146 		JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung ClinVar PMID:26619011 PMID:26822237 NCBI chr11:107,658,495...107,754,457
Ensembl chr11:107,658,453...107,752,637 		JBrowse link
G PTPN13 protein tyrosine phosphatase non-receptor type 13 exacerbates
susceptibility		 ISO mRNA,protein:decreased expression:lung
DNA:missense mutations:cds:p.I1522M, p.Y2081D (human)		 RGD PMID:19672627 PMID:22245727 PMID:33536603 RGD:152176663 RGD:152176665 RGD:152975626 NCBI chr 7:34,974,028...35,200,214
Ensembl chr 7:34,974,082...35,200,293 		JBrowse link
G PTPRB protein tyrosine phosphatase receptor type B disease_progression ISO mRNA:decreased expression:lung (human)
mRNA:altered expression:lung (human)		 RGD PMID:7981622 PMID:29254206 RGD:151665107 RGD:151665112 NCBI chr11:66,095,445...66,222,402
Ensembl chr11:66,101,038...66,221,982 		JBrowse link
G PTPRJ protein tyrosine phosphatase receptor type J susceptibility ISO DNA:missense mutations:cds:p.R326Q, p.Q276P (human) RGD PMID:19672627 RGD:152176665 NCBI chr 1:17,137,896...17,328,836
Ensembl chr 1:17,135,907...17,328,590 		JBrowse link
G RAC1 Rac family small GTPase 1 exacerbates
ameliorates		 ISO mRNA:increased expression:lung (human) RGD PMID:31779616 PMID:32366477 RGD:152998910 RGD:153345550 NCBI chr28:15,583,609...15,610,753
Ensembl chr28:15,583,516...15,610,328 		JBrowse link
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:1760348 PMID:8601312 PMID:10064593 PMID:12077328 PMID:17603482 More... NCBI chr22:48,560,270...48,643,537
Ensembl chr22:48,561,161...48,618,020 		JBrowse link
G RANGRF RAN guanine nucleotide release factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr16:7,654,235...7,655,851
Ensembl chr16:7,654,439...7,655,703 		JBrowse link
G RARB retinoic acid receptor beta ISO DNA:hypomethylation:lung RGD PMID:26695082 RGD:13464334 NCBI chr15:69,851,447...70,266,215
Ensembl chr15:70,096,117...70,264,905 		JBrowse link
G RASA1 RAS p21 protein activator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr 4:81,249,851...81,371,486
Ensembl chr 4:81,249,805...81,370,453 		JBrowse link
G RB1 RB transcriptional corepressor 1 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr 3:26,220,783...26,393,671
Ensembl chr 3:26,220,803...26,394,546 		JBrowse link
G RBM10 RNA binding motif protein 10 ISO mRNA, protein:decreased expression:lung
DNA:missense mutations, protein-truncating variants: :multiple		 RGD PMID:22980975 PMID:29085465 PMID:30955253 RGD:11097386 RGD:151356983 RGD:151356984 NCBI chr  X:44,339,653...44,373,509
Ensembl chr  X:44,339,877...44,373,339 		JBrowse link
G RFC4 replication factor C subunit 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr15:81,081,415...81,097,599
Ensembl chr15:81,081,481...81,097,272 		JBrowse link
G RHOA ras homolog family member A ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:26619011 NCBI chr22:10,757,381...10,809,257
Ensembl chr22:10,757,337...10,772,704 		JBrowse link
G RIN3 Ras and Rab interactor 3 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr24:70,261,693...70,447,126
Ensembl chr24:70,303,459...70,450,059 		JBrowse link
G RNASEH2A ribonuclease H2 subunit A ISO CTD Direct Evidence: marker/mechanism CTD PMID:34254728 NCBI chr 6:11,493,752...11,501,167
Ensembl chr 6:11,493,764...11,501,363 		JBrowse link
G RNF43 ring finger protein 43 severity ISO human cells in a mouse model RGD PMID:31286874 RGD:151361222 NCBI chr16:34,981,126...35,046,478
Ensembl chr16:34,980,922...35,045,107 		JBrowse link
G ROS1 ROS proto-oncogene 1, receptor tyrosine kinase ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:23724914 PMID:27993330 NCBI chr13:56,412,451...56,561,382
Ensembl chr13:56,413,298...56,562,503 		JBrowse link
G RPL10A ribosomal protein L10a ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr17:36,655,272...36,657,951
Ensembl chr17:36,653,183...36,658,033 		JBrowse link
G RPL13A ribosomal protein L13a ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 6:42,666,186...42,671,018 JBrowse link
G RPL27A ribosomal protein L27a ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:56,112,593...56,115,615
Ensembl chr 1:56,112,635...56,115,639 		JBrowse link
G RPSA ribosomal protein SA ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr15:23,915...29,889 JBrowse link
G RRM1 ribonucleotide reductase catalytic subunit M1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:62,606,112...62,649,979
Ensembl chr 1:62,604,486...62,650,200 		JBrowse link
G RRM2 ribonucleotide reductase regulatory subunit M2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr14:97,512,690...97,519,734
Ensembl chr14:97,512,832...97,521,932 		JBrowse link
G RRS1 ribosome biogenesis regulator 1 homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 8:62,297,483...62,299,194
Ensembl chr 8:62,297,608...62,298,705 		JBrowse link
G SATB1 SATB homeobox 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr15:63,163,989...63,263,122
Ensembl chr15:63,170,243...63,263,149 		JBrowse link
G SDC1 syndecan 1 ISO mRNA:increased expression:lung (human) RGD PMID:23374247 RGD:151708716 NCBI chr14:87,499,732...87,523,122
Ensembl chr14:87,499,574...87,525,026 		JBrowse link
G SERPINA3 serpin family A member 3 ISO protein:increased expression:cytoplasm RGD PMID:8620411 RGD:5147446 NCBI chr24:72,388,948...72,415,746
Ensembl chr24:72,402,560...72,415,507 		JBrowse link
G SETD2 SET domain containing 2, histone lysine methyltransferase severity
exacerbates
ameliorates		 ISO DNA:mutations:multiple (human)
human cells and genes in mouse model		 RGD PMID:27687306 PMID:28202515 PMID:33223508 PMID:33707235 RGD:126848875 RGD:150429633 RGD:150429648 RGD:150429649 NCBI chr22:8,421,178...8,567,221
Ensembl chr22:8,420,960...8,567,201 		JBrowse link
G SFN stratifin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr20:105,902,481...105,904,313
Ensembl chr20:105,902,974...105,903,720 		JBrowse link
G SFTPC surfactant protein C ISO CTD Direct Evidence: marker/mechanism CTD PMID:25851810 NCBI chr 8:20,229,756...20,233,568
Ensembl chr 8:20,230,870...20,234,020 		JBrowse link
G SFXN1 sideroflexin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr23:77,625,740...77,675,935
Ensembl chr23:77,625,775...77,674,907 		JBrowse link
G SHMT1 serine hydroxymethyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr16:17,371,704...17,408,499 JBrowse link
G SLC15A2 solute carrier family 15 member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr22:58,916,389...58,966,725
Ensembl chr22:58,913,676...58,966,906 		JBrowse link
G SLC19A1 solute carrier family 19 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 2:89,188,171...89,232,081
Ensembl chr 2:89,188,733...89,209,281 		JBrowse link
G SLC1A5 solute carrier family 1 member 5 disease_progression ISO RGD PMID:26279756 RGD:151361150 NCBI chr 6:40,139,417...40,150,312 JBrowse link
G SLC22A18 solute carrier family 22 member 18 disease_progression ISO mRNA:increased expression:lung (human)
ClinVar Annotator: match by term: Lung adenocarcinoma		 RGD
ClinVar		 PMID:27993330 PMID:32726996 RGD:150557423 NCBI chr 1:2,712,792...2,737,874
Ensembl chr 1:2,715,027...2,737,872 		JBrowse link
G SLC3A2 solute carrier family 3 member 2 disease_progression ISO RGD PMID:19171406 RGD:151361151 NCBI chr 1:11,011,351...11,050,494
Ensembl chr 1:11,008,120...11,050,298 		JBrowse link
G SLC4A4 solute carrier family 4 member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 7:19,581,399...20,043,334 JBrowse link
G SLC4A7 solute carrier family 4 member 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr15:71,942,498...72,047,781
Ensembl chr15:71,961,350...72,047,617 		JBrowse link
G SLC7A5 solute carrier family 7 member 5 disease_progression ISO RGD PMID:19171406 PMID:26279756 RGD:151361150 RGD:151361151 NCBI chr 5:73,229,953...73,269,801
Ensembl chr 5:73,229,951...73,269,754 		JBrowse link
G SMAD4 SMAD family member 4 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:6604412 PMID:8898652 PMID:9214508 PMID:9285566 PMID:9582123 More... NCBI chr18:29,894,157...29,951,445
Ensembl chr18:29,897,621...29,934,478 		JBrowse link
G SMARCC1 SWI/SNF related BAF chromatin remodeling complex subunit C1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr22:8,987,936...9,167,689
Ensembl chr22:8,987,012...9,134,946 		JBrowse link
G SNRPB small nuclear ribonucleoprotein polypeptides B and B1 severity ISO mRNA:increased expression:lung (human) RGD PMID:22876301 RGD:10768834 NCBI chr 2:54,064,240...54,073,341
Ensembl chr 2:54,063,999...54,073,367 		JBrowse link
G SNRPE small nuclear ribonucleoprotein polypeptide E severity ISO mRNA:increased expression:lung (human) RGD PMID:22876301 RGD:10768834 NCBI chr25:25,474,620...25,483,427 JBrowse link
G SNRPG small nuclear ribonucleoprotein polypeptide G ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr14:36,823,959...36,858,240
Ensembl chr14:36,826,779...36,837,137 		JBrowse link
G SOD2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr13:87,284,537...87,297,998
Ensembl chr13:87,280,686...87,297,974 		JBrowse link
G SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:25741868 PMID:26619011 NCBI chr14:68,259,509...68,404,167
Ensembl chr14:68,259,360...68,399,895 		JBrowse link
G SOX2 SRY-box transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25184679 NCBI chr15:7,673,581...7,676,812
Ensembl chr15:7,674,867...7,675,826 		JBrowse link
G SOX30 SRY-box transcription factor 30 disease_progression ISO RGD PMID:26330328 RGD:11535423 NCBI chr23:60,013,384...60,038,682
Ensembl chr23:60,014,046...60,037,997 		JBrowse link
G SPOP speckle type BTB/POZ protein ameliorates ISO mRNA, protein:increased expression:lung (human)
human gene and cell line in mouse model		 RGD PMID:30607139 PMID:31105033 RGD:153298920 RGD:153298927 NCBI chr16:69,990,554...70,073,241 JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase severity ISO RGD PMID:12826049 RGD:150521546 NCBI chr 2:26,344,480...26,367,448
Ensembl chr 2:26,343,450...26,367,776 		JBrowse link
G SRM spermidine synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr20:120,718,265...120,723,694
Ensembl chr20:120,718,424...120,723,944 		JBrowse link
G SRR serine racemase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr16:1,940,870...1,958,165
Ensembl chr16:1,940,893...1,956,783 		JBrowse link
G SRSF1 serine and arginine rich splicing factor 1 severity ISO RGD PMID:23071587 RGD:150429662 NCBI chr16:35,392,573...35,396,815
Ensembl chr16:35,392,873...35,394,982 		JBrowse link
G SRSF2 serine and arginine rich splicing factor 2 severity ISO RGD PMID:23071587 RGD:150429662 NCBI chr16:44,945,193...44,948,496
Ensembl chr16:44,945,200...44,946,438 		JBrowse link
G STK11 serine/threonine kinase 11 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:10408777 PMID:12865922 PMID:15561763 PMID:15863673 PMID:16287113 More... NCBI chr 6:973,033...996,857
Ensembl chr 6:974,144...995,136 		JBrowse link
G STK39 serine/threonine kinase 39 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr10:53,451,035...53,747,847
Ensembl chr10:53,450,891...53,682,993 		JBrowse link
G STRBP spermatid perinuclear RNA binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr12:14,944,447...15,023,703
Ensembl chr12:14,948,763...15,011,359 		JBrowse link
G SUCLG2 succinate-CoA ligase GDP-forming subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr22:28,382,612...28,677,749
Ensembl chr22:28,381,787...28,677,742 		JBrowse link
G TERT telomerase reverse transcriptase susceptibility ISO DNA:SNP: :rs2736098(human)
DNA:SNP::rs33963617(human)
DNA:SNPs:: rs2853669,rs2736108(human)
DNA:SNP:: rs2736100(human)		 RGD PMID:19955392 PMID:23738012 PMID:23908149 PMID:24761905 PMID:31935503 RGD:150530485 RGD:150530498 RGD:150530502 RGD:150530628 RGD:150530635 NCBI chr 4:1,082,894...1,119,373
Ensembl chr 4:1,083,384...1,117,468 		JBrowse link
G TF transferrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr15:56,586,311...56,618,304
Ensembl chr15:56,586,104...56,618,149 		JBrowse link
G TGFB2 transforming growth factor beta 2 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr25:11,163,651...11,259,868
Ensembl chr25:11,163,100...11,258,470 		JBrowse link
G TIMM10 translocase of inner mitochondrial membrane 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:15,701,586...15,703,867
Ensembl chr 1:15,701,469...15,703,900 		JBrowse link
G TIMM8A translocase of inner mitochondrial membrane 8A ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr  X:89,686,772...89,690,088
Ensembl chr  X:89,687,304...89,689,810 		JBrowse link
G TIMP3 TIMP metallopeptidase inhibitor 3 ISO mRNA:decreased expression:lung (human) RGD PMID:23374247 RGD:151708716 NCBI chr19:15,621,609...15,684,118
Ensembl chr19:15,622,431...15,680,449 		JBrowse link
G TK1 thymidine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr16:70,186,103...70,200,689
Ensembl chr16:70,186,767...70,200,610 		JBrowse link
G TLR4 toll like receptor 4 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr12:21,873,762...21,885,562
Ensembl chr12:21,871,773...21,885,515 		JBrowse link
G TNFSF10 TNF superfamily member 10 ISO CTD Direct Evidence: therapeutic CTD PMID:24345465 NCBI chr15:16,934,982...16,953,155
Ensembl chr15:16,934,962...16,954,860 		JBrowse link
G TOMM40 translocase of outer mitochondrial membrane 40 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 6:38,363,060...38,375,098
Ensembl chr 6:38,363,176...38,375,218 		JBrowse link
G TOP2A DNA topoisomerase II alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr16:65,761,391...65,792,041
Ensembl chr16:65,761,416...65,792,701 		JBrowse link
G TP53 tumor protein p53 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Adenocarcinoma of lung, somatic | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:124622 PMID:253702 PMID:960674 PMID:1349175 PMID:1565143 More... NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223 		JBrowse link
G TP63 tumor protein p63 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24880342 NCBI chr15:83,861,489...84,126,675 JBrowse link
G TPI1 triosephosphate isomerase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr11:6,900,762...6,904,188
Ensembl chr11:6,900,787...6,906,787 		JBrowse link
G TRAF4 TNF receptor associated factor 4 ISO mRNA:increased expression:lung (human) RGD PMID:29254206 RGD:151665107 NCBI chr16:22,507,915...22,513,956
Ensembl chr16:22,507,835...22,515,335 		JBrowse link
G TTF1 transcription termination factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25851810 NCBI chr12:5,734,136...5,763,768
Ensembl chr12:5,738,166...5,764,533 		JBrowse link
G TTR transthyretin ISO mRNA,protein:increased expression:lung (human) RGD PMID:26943652 RGD:151665207 NCBI chr18:49,124,302...49,131,495
Ensembl chr18:49,124,121...49,131,399 		JBrowse link
G TYMS thymidylate synthetase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr18:60,030,640...60,043,297
Ensembl chr18:60,030,658...60,041,856 		JBrowse link
G UBR5 ubiquitin protein ligase E3 component n-recognin 5 ameliorates ISO human cell line in a mouse model RGD PMID:32867711 RGD:151665200 NCBI chr 8:97,104,325...97,257,317
Ensembl chr 8:97,103,220...97,257,440 		JBrowse link
G UCK2 uridine-cytidine kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr25:62,974,515...63,059,436
Ensembl chr25:62,974,257...63,059,414 		JBrowse link
G VAV1 vav guanine nucleotide exchange factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr 6:6,337,255...6,415,851 JBrowse link
G WRAP53 WD repeat containing antisense to TP53 severity ISO RGD PMID:28347242 RGD:21081522 NCBI chr16:7,065,531...7,085,590
Ensembl chr16:7,066,333...7,085,625 		JBrowse link
G XPC XPC complex subunit, DNA damage recognition and repair factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21327329 PMID:27777383 NCBI chr22:50,088,019...50,121,584
Ensembl chr22:50,085,353...50,121,542 		JBrowse link
G XPO1 exportin 1 exacerbates ISO circRNA:increased expression:lung (human)
mRNA:increased expression:lung (human)		 RGD PMID:23639940 PMID:33268793 RGD:151665799 RGD:151665801 NCBI chr14:45,428,279...45,487,965
Ensembl chr14:45,432,619...45,488,723 		JBrowse link
G XRCC1 X-ray repair cross complementing 1 severity
susceptibility		 ISO DNA:missense mutation:exon 10: p.R399Q (rs25487) (human)
DNA:missense mutation:cds: p.R399Q (human)		 RGD PMID:11104903 PMID:20003463 RGD:151347406 RGD:151347422 NCBI chr 6:37,062,149...37,095,138
Ensembl chr 6:37,060,439...37,095,094 		JBrowse link
G XRCC5 X-ray repair cross complementing 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr10:101,952,909...102,051,059
Ensembl chr10:101,953,067...102,049,964 		JBrowse link
G XRCC6 X-ray repair cross complementing 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr19:24,160,459...24,204,237
Ensembl chr19:24,160,483...24,206,320 		JBrowse link
G ZFHX3 zinc finger homeobox 3 ameliorates ISO DNA:mutations:multiple (human) RGD PMID:32653938 RGD:151361163 NCBI chr 5:55,912,325...56,174,010
Ensembl chr 5:55,907,983...56,085,112 		JBrowse link
lung carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E ISO RGD PMID:24175756 RGD:11040551 NCBI chr 6:38,377,154...38,381,219
Ensembl chr 6:38,376,887...38,381,438 		JBrowse link
G ARHGAP44 Rho GTPase activating protein 44 ISO mRNA:decreased expression:lung (human) RGD PMID:28527113 RGD:401901290 NCBI chr16:12,125,543...12,328,203
Ensembl chr16:12,125,574...12,330,501 		JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Lung carcinoma ClinVar PMID:11313766 PMID:12068308 PMID:12198537 PMID:12447372 PMID:12460918 More... NCBI chr21:109,495,525...109,690,261 JBrowse link
G CHRNA3 cholinergic receptor nicotinic alpha 3 subunit susceptibility ISO DNA:SNP: :rs1051730(human) RGD PMID:24337855 RGD:151347533 NCBI chr26:4,721,145...4,747,694
Ensembl chr26:4,722,489...4,737,164 		JBrowse link
G CRKL CRK like proto-oncogene, adaptor protein ISO RGD PMID:16391854 RGD:7488899
G CTNNA1 catenin alpha 1 ISO RGD PMID:15195114 RGD:2289804 NCBI chr23:41,423,504...41,599,458
Ensembl chr23:41,447,675...41,600,190 		JBrowse link
G CTNNB1 catenin beta 1 disease_progression ISO DNA, protein:mutations, increased expression:cytoplasm, nucleus:multiple RGD PMID:17639448 RGD:2289843 NCBI chr22:2,679,488...2,725,034
Ensembl chr22:2,684,022...2,723,949 		JBrowse link
G CYP24A1 cytochrome P450 family 24 subfamily A member 1 susceptibility ISO DNA:SNP:3' utr: (rs4809957) (human) RGD PMID:22797725 RGD:151665791 NCBI chr 2:9,868,794...9,889,510
Ensembl chr 2:9,868,678...9,885,884 		JBrowse link
G DNMT1 DNA methyltransferase 1 disease_progression ISO protein:increased expression:nucleus: RGD PMID:21163286 RGD:9588222 NCBI chr 6:9,199,006...9,263,890
Ensembl chr 6:9,199,003...9,263,607 		JBrowse link
G DNMT3A DNA methyltransferase 3 alpha disease_progression ISO protein:increased expression:nucleus: RGD PMID:21163286 RGD:9588222 NCBI chr14:82,313,414...82,427,170
Ensembl chr14:82,402,826...82,420,819 		JBrowse link
G EGFR epidermal growth factor receptor ISO ClinVar Annotator: match by term: Lung carcinoma ClinVar PMID:11423618 PMID:15118073 PMID:15118125 PMID:15272417 PMID:15329413 More... NCBI chr21:3,664,622...3,853,492
Ensembl chr21:3,666,339...3,853,239 		JBrowse link
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit ISO RGD PMID:21530494 RGD:10045659 NCBI chr 6:38,857,067...38,900,177
Ensembl chr 6:38,854,803...38,872,967 		JBrowse link
G FOXA1 forkhead box A1 ameliorates ISO RGD PMID:31221478 RGD:151665930 NCBI chr24:14,397,759...14,403,078
Ensembl chr24:14,396,702...14,403,094 		JBrowse link
G GPX3 glutathione peroxidase 3 ISO protein decreased expression:heart RGD PMID:33693448 RGD:401827836 NCBI chr23:53,576,950...53,585,321 JBrowse link
G JAK2 Janus kinase 2 treatment ISO human cells in mouse model RGD PMID:26397387 RGD:11529462 NCBI chr12:74,421,243...74,566,766
Ensembl chr12:74,421,016...74,566,710 		JBrowse link
G KDR kinase insert domain receptor treatment ISO RGD PMID:16763608 PMID:20118536 RGD:126925177 RGD:126925190 NCBI chr 7:13,435,059...13,482,236
Ensembl chr 7:13,435,096...13,482,771 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Lung carcinoma ClinVar PMID:2278970 PMID:3122217 PMID:6320174 PMID:7773929 PMID:8439212 More... NCBI chr11:24,963,396...25,010,747
Ensembl chr11:24,973,619...25,005,191 		JBrowse link
G LOC103242066 mucin-4 ISO protein:altered expression:lung RGD PMID:11596032 RGD:5131258 NCBI chr15:91,313,060...91,345,172 JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 exacerbates ISO DNA:missense mutation:CDS:p.E116K (human) RGD PMID:27028764 RGD:11529413 NCBI chr 6:7,355,387...7,365,944
Ensembl chr 6:7,355,434...7,364,398 		JBrowse link
G MDC1 mediator of DNA damage checkpoint 1 ISO protein:decreased expression:bronchus, parenchyma (human) RGD PMID:17546051 RGD:9589053 NCBI chr17:41,735,584...41,754,618
Ensembl chr17:41,739,419...41,755,141 		JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase ISO ClinVar Annotator: match by term: Lung carcinoma ClinVar PMID:26637977 PMID:26892698 NCBI chr21:85,370,574...85,486,405
Ensembl chr21:85,397,645...85,488,093 		JBrowse link
G MLH1 mutL homolog 1 ISO RGD PMID:21530494 RGD:10045659 NCBI chr15:2,364,537...2,418,379
Ensembl chr15:2,364,738...2,418,393 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 ISO ClinVar Annotator: match by term: Lung carcinoma ClinVar PMID:1737339 PMID:6933553 PMID:9000600 PMID:9230185 PMID:9328142 More... NCBI chr 5:57,676,547...57,695,434
Ensembl chr 5:57,675,981...57,716,599 		JBrowse link
G PFAS phosphoribosylformylglycinamidine synthase ISO RGD PMID:6722784 RGD:5135276 NCBI chr16:7,618,952...7,639,700
Ensembl chr16:7,623,817...7,638,594 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO ClinVar Annotator: match by term: Lung carcinoma ClinVar PMID:15016963 PMID:15254419 PMID:15520168 PMID:15647370 PMID:15805248 More... NCBI chr15:10,218,034...10,304,874
Ensembl chr15:10,218,805...10,294,316 		JBrowse link
G PPM1D protein phosphatase, Mg2+/Mn2+ dependent 1D ISO ClinVar Annotator: match by term: Lung carcinoma ClinVar PMID:23907125 PMID:24262437 PMID:25741868 PMID:28343630 PMID:28852847 More... NCBI chr16:31,833,145...31,900,962
Ensembl chr16:31,833,160...31,900,963 		JBrowse link
G PPP2R1B protein phosphatase 2 scaffold subunit Abeta ISO ClinVar Annotator: match by term: Lung carcinoma ClinVar PMID:9765152 PMID:11996789 NCBI chr 1:103,058,283...103,110,839
Ensembl chr 1:103,057,915...103,110,102 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase ISO ClinVar Annotator: match by term: Lung carcinoma ClinVar PMID:10072423 PMID:11558785 PMID:11889248 PMID:12114481 PMID:12730996 More... NCBI chr13:88,856,056...90,329,379 JBrowse link
G ROCK1 Rho associated coiled-coil containing protein kinase 1 ISO ClinVar Annotator: match by term: Lung carcinoma ClinVar PMID:20140017 NCBI chr18:59,384,822...59,538,780
Ensembl chr18:59,384,944...59,540,070 		JBrowse link
G SLC22A18 solute carrier family 22 member 18 ISO ClinVar Annotator: match by term: Lung carcinoma ClinVar PMID:9751628 NCBI chr 1:2,712,792...2,737,874
Ensembl chr 1:2,715,027...2,737,872 		JBrowse link
G SOX9 SRY-box transcription factor 9 exacerbates ISO RGD PMID:31221478 RGD:151665930 NCBI chr16:49,519,749...49,523,967
Ensembl chr16:49,518,185...49,523,898 		JBrowse link
G STRAP serine/threonine kinase receptor associated protein ISO RGD PMID:16778189 RGD:1581429 NCBI chr11:15,790,449...15,812,964
Ensembl chr11:15,790,798...15,813,585 		JBrowse link
G XPO1 exportin 1 ameliorates ISO human cell line in a mouse model RGD PMID:25629636 RGD:11058563 NCBI chr14:45,428,279...45,487,965
Ensembl chr14:45,432,619...45,488,723 		JBrowse link
lung large cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARHGAP44 Rho GTPase activating protein 44 ISO mRNA:decreased expression:lung (human) RGD PMID:28527113 RGD:401901290 NCBI chr16:12,125,543...12,328,203
Ensembl chr16:12,125,574...12,330,501 		JBrowse link
G CHRNA5 cholinergic receptor nicotinic alpha 5 subunit ISO mRNA:increased expression:lung RGD PMID:20124469 RGD:150527851 NCBI chr26:4,747,734...4,779,231
Ensembl chr26:4,749,766...4,776,822 		JBrowse link
G DLL4 delta like canonical Notch ligand 4 treatment ISO RGD PMID:33628824 RGD:155663482 NCBI chr26:42,056,473...42,066,283
Ensembl chr26:42,056,331...42,065,828 		JBrowse link
G NOTCH1 notch receptor 1 treatment ISO RGD PMID:33628824 RGD:155663482 NCBI chr12:1,656,815...1,707,566
Ensembl chr12:1,656,918...1,709,585 		JBrowse link
G PTPN13 protein tyrosine phosphatase non-receptor type 13 ISO mRNA,protein:decreased expression:lung RGD PMID:22245727 RGD:152176663 NCBI chr 7:34,974,028...35,200,214
Ensembl chr 7:34,974,082...35,200,293 		JBrowse link
G TTR transthyretin ISO protein:increased expression:lung (human) RGD PMID:26943652 RGD:151665207 NCBI chr18:49,124,302...49,131,495
Ensembl chr18:49,124,121...49,131,399 		JBrowse link
lung metastasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM28 ADAM metallopeptidase domain 28 ameliorates ISO associated with lung adenocarcinoma;
associated with lung carcinoma, breast carcinoma		 RGD PMID:22636800 PMID:26800504 RGD:11531771 RGD:153297785 NCBI chr 8:22,424,260...22,483,878
Ensembl chr 8:22,430,579...22,488,257 		JBrowse link
G ARHGAP5 Rho GTPase activating protein 5 ISO associated with Mammary Neoplasms, Experimental RGD PMID:20860838 RGD:126848767 NCBI chr24:8,914,485...8,986,498
Ensembl chr24:8,928,252...8,988,302 		JBrowse link
G ARID2 AT-rich interaction domain 2 exacerbates ISO associated with hepatocellular carcinoma, RGD PMID:32071245 RGD:150340708 NCBI chr11:41,933,650...42,117,495
Ensembl chr11:42,028,083...42,118,892 		JBrowse link
G AZGP1 alpha-2-glycoprotein 1, zinc-binding ameliorates ISO associated with hepatocellular carcinoma; RGD PMID:26902423 PMID:27993894 RGD:153350132 RGD:153350133 NCBI chr28:13,104,262...13,120,329
Ensembl chr28:13,104,323...13,120,363 		JBrowse link
G CA12 carbonic anhydrase 12 ameliorates ISO associated with breast cancer; RGD PMID:29786141 RGD:155226861 NCBI chr26:20,162,706...20,221,680
Ensembl chr26:20,162,926...20,224,502 		JBrowse link
G CBLB Cbl proto-oncogene B severity ISO associated with stomach carcinoma; RGD PMID:28334634 RGD:150540337 NCBI chr22:74,961,831...75,181,307
Ensembl chr22:74,961,859...75,178,548 		JBrowse link
G CHD4 chromodomain helicase DNA binding protein 4 ameliorates ISO associated with human colon adenocarcinoma cells in a mouse model RGD PMID:28486105 RGD:153323299 NCBI chr11:6,603,820...6,641,278
Ensembl chr11:6,602,694...6,640,351 		JBrowse link
G COL10A1 collagen type X alpha 1 chain ameliorates ISO associated with H1299 cell RGD PMID:33324550 RGD:150429752 NCBI chr13:57,657,310...57,697,955
Ensembl chr13:57,691,409...57,696,783 		JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 ameliorates ISO associated with colorectal cancer; human cells in mouse model
associated with nasopharynx carcinoma; human cells in mouse model
associated with osteosarcoma and melanoma		 RGD PMID:16000558 PMID:18071913 PMID:26498029 PMID:31938138 RGD:151665329 RGD:151893515 RGD:152023752 RGD:152177473 NCBI chr10:20,336,470...20,340,308
Ensembl chr10:20,336,247...20,340,309 		JBrowse link
G DDR1 discoidin domain receptor tyrosine kinase 1 ISO RGD PMID:29483153 RGD:151347599 NCBI chr17:41,564,271...41,583,404
Ensembl chr17:41,564,992...41,575,682 		JBrowse link
G DDR2 discoidin domain receptor tyrosine kinase 2 exacerbates ISO associated with tongue squamous cell carcinoma; RGD PMID:24556606 RGD:150429746 NCBI chr20:1,298,636...1,451,872
Ensembl chr20:1,299,574...1,359,674 		JBrowse link
G FASN fatty acid synthase ISO associated with head and neck squamous cell carcinoma RGD PMID:20604875 RGD:126790467 NCBI chr16:73,988,410...74,008,374
Ensembl chr16:73,982,899...74,006,551 		JBrowse link
G FOSL2 FOS like 2, AP-1 transcription factor subunit ISO human cells in mouse model RGD PMID:30326930 RGD:153344557 NCBI chr14:79,201,128...79,222,363
Ensembl chr14:79,201,649...79,222,373 		JBrowse link
G HILPDA hypoxia inducible lipid droplet associated ISO human cells in mouse model RGD PMID:31142329 RGD:153344574 NCBI chr21:97,254,246...97,257,186 JBrowse link
G IQSEC1 IQ motif and Sec7 domain ArfGEF 1 ISO