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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:crescentic glomerulonephritis
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Accession:DOID:13139 term browser browse the term
Definition:A syndrome of the kidney that is characterized by a rapid loss of renal function involving severe injury to the kidneys' glomeruli, with many of the glomeruli containing characteristic glomerular crescents (crescent-shaped scars).
Synonyms:exact_synonym: RPGN;   rapidly progressive glomerulonephritis
 related_synonym: NCGN;   necrotizing crescentic glomerulonephritis
 primary_id: RDO:9000021
 xref: NCI:C128143;   NCI:C35444
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
 
crescentic glomerulonephritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 treatment IMP
IDA
RGD PMID:8903512, PMID:17314328 RGD:8549743, RGD:8549770 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 ISO
IEP
associated with Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis RGD PMID:18846416, PMID:17898087 RGD:7241813, RGD:2307059 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Cd40 CD40 molecule ISO RGD PMID:14569091 RGD:7248599 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704
JBrowse link
G Cd40lg CD40 ligand treatment ISO RGD PMID:14569091 RGD:7248599 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562
JBrowse link
G Fcgr2a Fc fragment of IgG receptor IIa IAGP DNA:CNV:3'UTR: RGD PMID:16482158 RGD:2293335 NCBI chr13:91,146,878...91,163,691
Ensembl chr13:91,168,973...91,198,036
Ensembl chr13:91,168,973...91,198,036
JBrowse link
G Il1b interleukin 1 beta IDA RGD PMID:19959716 RGD:7175502 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rn interleukin 1 receptor antagonist treatment ISO human protein in a rat model RGD PMID:7637259 RGD:8551712 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Mmp12 matrix metallopeptidase 12 IEP
IMP
RGD PMID:20488952, PMID:12626598 RGD:2325762, RGD:737630 NCBI chr 8:5,594,717...5,616,494
Ensembl chr 8:5,606,592...5,616,493
JBrowse link
G Mmp3 matrix metallopeptidase 3 IEP RGD PMID:11095647 RGD:7241255 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579
JBrowse link
G Mmp9 matrix metallopeptidase 9 IEP protein:increased expression:renal cortex (rat) RGD PMID:16046515 RGD:2313720 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mtor mechanistic target of rapamycin kinase IMP RGD PMID:21403644 RGD:7245940 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Stat6 signal transducer and activator of transcription 6 ISO RGD PMID:21985369 RGD:7243976 NCBI chr 7:70,946,228...70,963,542
Ensembl chr 7:70,946,228...70,964,484
JBrowse link
G Tlr9 toll-like receptor 9 severity ISO RGD PMID:20847283 RGD:7246899 NCBI chr 8:114,916,122...114,920,171
Ensembl chr 8:114,916,122...114,920,171
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16058
    syndrome 6996
      crescentic glomerulonephritis 15
Path 2
Term Annotations click to browse term
  disease 16058
    disease of anatomical entity 15305
      Urogenital Diseases 4146
        urinary system disease 2069
          kidney disease 1857
            nephritis 421
              glomerulonephritis 371
                acute proliferative glomerulonephritis 15
                  crescentic glomerulonephritis 15
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.