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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:crescentic glomerulonephritis
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Accession:DOID:13139 term browser browse the term
Definition:A syndrome of the kidney that is characterized by a rapid loss of renal function involving severe injury to the kidneys' glomeruli, with many of the glomeruli containing characteristic glomerular crescents (crescent-shaped scars).
Synonyms:exact_synonym: RPGN;   rapidly progressive glomerulonephritis
 related_synonym: NCGN;   necrotizing crescentic glomerulonephritis
 primary_id: RDO:9000021
 xref: NCI:C128143;   NCI:C35444
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
 
crescentic glomerulonephritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 treatment IMP
IDA
RGD PMID:8903512 PMID:17314328 RGD:8549743, RGD:8549770 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 ISO
IEP
associated with Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis RGD PMID:18846416 PMID:17898087 RGD:7241813, RGD:2307059 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Cd40 CD40 molecule ISO RGD PMID:14569091 RGD:7248599 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cd40lg CD40 ligand treatment ISO RGD PMID:14569091 RGD:7248599 NCBI chr  X:135,127,119...135,138,302
Ensembl chr  X:135,126,969...135,138,306
JBrowse link
G Fcgr2a Fc fragment of IgG receptor IIa IAGP DNA:CNV:3'UTR: RGD PMID:16482158 RGD:2293335 NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967
JBrowse link
G Il1b interleukin 1 beta IDA RGD PMID:19959716 RGD:7175502 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1rn interleukin 1 receptor antagonist treatment ISO human protein in a rat model RGD PMID:7637259 RGD:8551712 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit IEP RGD PMID:18443593 RGD:2293336 NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799
JBrowse link
G Mmp12 matrix metallopeptidase 12 IEP
IMP
RGD PMID:20488952 PMID:12626598 RGD:2325762, RGD:737630 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611
JBrowse link
G Mmp3 matrix metallopeptidase 3 IEP RGD PMID:11095647 RGD:7241255 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
JBrowse link
G Mmp9 matrix metallopeptidase 9 IEP protein:increased expression:renal cortex (rat) RGD PMID:16046515 RGD:2313720 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mtor mechanistic target of rapamycin kinase IMP RGD PMID:21403644 RGD:7245940 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Stat6 signal transducer and activator of transcription 6 ISO RGD PMID:21985369 RGD:7243976 NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495
JBrowse link
G Tlr9 toll-like receptor 9 severity ISO RGD PMID:20847283 RGD:7246899 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17205
    syndrome 8125
      crescentic glomerulonephritis 16
Path 2
Term Annotations click to browse term
  disease 17205
    disease of anatomical entity 16551
      Urogenital Diseases 4356
        urinary system disease 2143
          kidney disease 1923
            nephritis 445
              glomerulonephritis 390
                acute proliferative glomerulonephritis 16
                  crescentic glomerulonephritis 16
paths to the root