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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:intracranial vasospasm
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Accession:DOID:13100 term browser browse the term
Definition:Constriction of arteries in the SKULL due to sudden, sharp, and often persistent smooth muscle contraction in blood vessels. Intracranial vasospasm results in reduced vessel lumen caliber, restricted blood flow to the brain, and BRAIN ISCHEMIA that may lead to hypoxic-ischemic brain injury (HYPOXIA-ISCHEMIA, BRAIN).
Synonyms:exact_synonym: Cerebral Angiospasm;   Cerebral Angiospasms;   Cerebral Artery Spasm;   Cerebral Artery Spasms;   Cerebral Vasospasm;   Cerebral Vasospasms;   Cerebrovascular Spasm;   Cerebrovascular Spasms;   Intracranial Angiospasm;   Intracranial Angiospasms;   Intracranial Vascular Spasm;   Intracranial Vascular Spasms;   Intracranial Vasospasms
 primary_id: MESH:D020301;   RDO:0007389
For additional species annotation, visit the Alliance of Genome Resources.


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intracranial vasospasm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 IEP associated with Subarachnoid Hemorrhage;mRNA, protein:increased expression:basilar artery RGD PMID:19401162 RGD:2306995 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Hmox1 heme oxygenase 1 treatment IMP
ISO
associated with Subarachnoid Hemorrhage RGD PMID:19686725, PMID:21654696, PMID:14657544 RGD:4145300, RGD:10755572, RGD:1598406 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Plat plasminogen activator, tissue type ISO CTD Direct Evidence: therapeutic CTD PMID:19057314, PMID:29651748 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G S100a1 S100 calcium binding protein A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12186470 NCBI chr 2:189,900,505...189,905,348
Ensembl chr 2:189,900,667...189,903,219
JBrowse link
G S100a4 S100 calcium-binding protein A4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12186470 NCBI chr 2:189,997,278...189,999,587
Ensembl chr 2:189,997,129...189,999,604
JBrowse link
G S100a6 S100 calcium binding protein A6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12186470 NCBI chr 2:190,007,013...190,008,512
Ensembl chr 2:190,007,216...190,008,511
JBrowse link
G S100b S100 calcium binding protein B ISO CTD Direct Evidence: marker/mechanism CTD PMID:12186470 NCBI chr20:13,130,633...13,142,856
Ensembl chr20:13,130,636...13,142,856
JBrowse link
G Tnc tenascin C ISO associated with Subarachnoid Hemorrhage;protein:increased expression:serum RGD PMID:19589197 RGD:4889600 NCBI chr 5:79,789,686...79,874,555
Ensembl chr 5:79,789,671...79,874,671
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16058
    disease of anatomical entity 15305
      cardiovascular system disease 4454
        vascular disease 3386
          cerebrovascular disease 831
            intracranial vasospasm 8
Path 2
Term Annotations click to browse term
  disease 16058
    disease of anatomical entity 15305
      nervous system disease 10879
        central nervous system disease 9021
          brain disease 8346
            cerebrovascular disease 831
              intracranial vasospasm 8
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.