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ONTOLOGY REPORT - ANNOTATIONS
Term:agranulocytosis
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Accession:DOID:12987 term browser browse the term
Definition:A decrease in the number of GRANULOCYTES; (BASOPHILS; EOSINOPHILS; and NEUTROPHILS).
Synonyms:exact_synonym: Agranulocytoses;   Granulocytopenia;   Granulocytopenias;   Granulocytopenic disorder;   Granulopenia
 primary_id: MESH:D000380;   RDO:0004111
 xref: NCI:C2863
For additional species annotation, visit the Alliance of Genome Resources.

show annotations for term's descendants       view all columns           Sort by:
 
agranulocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Csf2 colony stimulating factor 2 JBrowse link 10 39,602,089 39,604,070 RGD:11554173
G Csf3 colony stimulating factor 3 JBrowse link 10 86,616,785 86,619,160 RGD:11554173
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:10450883
G Nqo2 N-ribosyldihydronicotinamide:quinone reductase 2 JBrowse link 17 32,131,847 32,158,559 RGD:11073696
RGD:11554173
G RT1-Bb RT1 class II, locus Bb JBrowse link 20 4,043,726 4,049,367 RGD:11041752
3-methylglutaconic aciduria with cataracts, neurologic involvement and neutropenia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Clpb caseinolytic mitochondrial matrix peptidase chaperone subunit B JBrowse link 1 166,739,372 166,866,095 RGD:7240710
RGD:8554872
Chemotherapy-Induced Febrile Neutropenia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ace angiotensin I converting enzyme JBrowse link 10 94,170,766 94,213,831 RGD:11038917
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 JBrowse link 12 19,074,288 19,114,491 RGD:11353804
G Fcgr3a Fc fragment of IgG receptor IIIa JBrowse link 13 89,385,775 89,396,047 RGD:11344967
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:10755412
G Itpa inosine triphosphatase JBrowse link 3 123,209,611 123,221,266 RGD:10766478
G Mbl2 mannose binding lectin 2 JBrowse link 1 248,435,069 248,442,669 RGD:11530041
RGD:11530056
RGD:11530043
G Mdm2 MDM2 proto-oncogene JBrowse link 7 60,719,060 60,743,618 RGD:11073725
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:11073725
cyclic hematopoiesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Elane elastase, neutrophil expressed JBrowse link 7 12,638,320 12,640,168 RGD:7240710
RGD:8554872
RGD:10450519
Drug-Induced Agranulocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Csf3 colony stimulating factor 3 JBrowse link 10 86,616,785 86,619,160 RGD:11039034
RGD:11039041
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:10450883
G Il1rn interleukin 1 receptor antagonist JBrowse link 3 1,449,778 1,468,624 RGD:11528539
G Nat2 N-acetyltransferase 2 JBrowse link 16 23,960,709 23,991,570 RGD:11532771
Drug-induced Neutropenia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:11080964
RGD:11081001
RGD:11080979
G Abcc2 ATP binding cassette subfamily C member 2 JBrowse link 1 263,554,426 263,612,556 RGD:11080980
RGD:11080999
G Csf3 colony stimulating factor 3 JBrowse link 10 86,616,785 86,619,160 RGD:11039035
RGD:11039036
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 JBrowse link 1 147,236,480 147,307,988 RGD:11353800
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 JBrowse link 12 19,074,288 19,114,491 RGD:11353800
RGD:11353804
G Dpyd dihydropyrimidine dehydrogenase JBrowse link 2 221,823,692 222,694,627 RGD:11251736
RGD:11098817
RGD:11251738
RGD:11251737
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link 1 80,256,973 80,268,198 RGD:11340199
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit JBrowse link 1 80,293,574 80,307,334 RGD:11098572
G Fcgr3a Fc fragment of IgG receptor IIIa JBrowse link 13 89,385,775 89,396,047 RGD:11344964
RGD:11352256
RGD:11344973
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:10755330
G Gstt1 glutathione S-transferase theta 1 JBrowse link 20 13,799,102 13,816,527 RGD:10755330
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:11051963
G Mdm2 MDM2 proto-oncogene JBrowse link 7 60,719,060 60,743,618 RGD:11073715
G RT1-Bb RT1 class II, locus Bb JBrowse link 20 4,043,726 4,049,367 RGD:14928329
G Slco1b2 solute carrier organic anion transporter family member 1B2 JBrowse link 4 175,814,118 175,881,775 RGD:11080980
RGD:11080999
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:11035278
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:11073715
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 JBrowse link 9 95,295,701 95,302,822 RGD:10768826
RGD:10769339
RGD:10769336
RGD:10769334
RGD:10768867
Dursun Syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G G6pc3 glucose 6 phosphatase catalytic subunit 3 JBrowse link 10 90,134,193 90,138,425 RGD:8554872
Febrile Neutropenia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:11528559
neutropenia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:11554173
G Ap3b1 adaptor related protein complex 3 subunit beta 1 JBrowse link 2 24,022,815 24,227,522 RGD:1578409
G C5 complement C5 JBrowse link 3
3		 14,049,993
14,206,466		 14,113,931
14,229,141		 RGD:5130180
RGD:1600665
G C5ar1 complement C5a receptor 1 JBrowse link 1 78,186,777 78,195,132 RGD:5130180
G Csf2 colony stimulating factor 2 JBrowse link 10 39,602,089 39,604,070 RGD:10449510
RGD:11554173
G Csf3 colony stimulating factor 3 JBrowse link 10 86,616,785 86,619,160 RGD:11039039
RGD:11554173
G Dpyd dihydropyrimidine dehydrogenase JBrowse link 2 221,823,692 222,694,627 RGD:11554173
G Elane elastase, neutrophil expressed JBrowse link 7 12,638,320 12,640,168 RGD:11554173
RGD:8554872
G Fcgr2a Fc fragment of IgG receptor IIa JBrowse link 13 91,146,878 91,163,691 RGD:11040988
G Fcgr2b Fc fragment of IgG receptor IIb JBrowse link 13 89,329,298 89,343,916 RGD:11554173
G Gfi1 growth factor independent 1 transcriptional repressor JBrowse link 14 3,058,035 3,073,332 RGD:11040449
RGD:11040456
G Gstt1 glutathione S-transferase theta 1 JBrowse link 20 13,799,102 13,816,527 RGD:10450844
G Hax1 HCLS1 associated protein X-1 JBrowse link 2 189,330,900 189,333,305 RGD:8554872
G Hoxd13 homeo box D13 JBrowse link 3 61,590,376 61,593,692 RGD:11554173
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:11554173
G Jagn1 jagunal homolog 1 JBrowse link 4 145,399,885 145,404,605 RGD:11554173
G Mki67 marker of proliferation Ki-67 JBrowse link 1 207,993,895 208,020,454 RGD:6483522
G Mthfr methylenetetrahydrofolate reductase JBrowse link 5 164,844,642 164,864,360 RGD:11554173
G Nup98 nucleoporin 98 and 96 precursor JBrowse link 1 167,213,866 167,308,851 RGD:11554173
G Ptafr platelet-activating factor receptor JBrowse link 5 150,746,284 150,775,675 RGD:10043179
G Rps14 ribosomal protein S14 JBrowse link 18 56,042,532 56,047,316 RGD:11554173
G Smarcd2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 JBrowse link 10 94,451,866 94,460,732 RGD:11554173
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:6892936
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1580321
G Tnfrsf10b tumor necrosis factor receptor superfamily, member 10b JBrowse link 15 51,433,853 51,464,215 RGD:11554173
G Tpmt thiopurine S-methyltransferase JBrowse link 17 18,029,090 18,047,716 RGD:11554173
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 JBrowse link 9 95,295,701 95,302,822 RGD:11554173
Nonimmune Chronic Idiopathic Neutropenia, Adult term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gfi1 growth factor independent 1 transcriptional repressor JBrowse link 14 3,058,035 3,073,332 RGD:7240710
RGD:8554872
G Tert telomerase reverse transcriptase JBrowse link 1 32,250,876 32,275,330 RGD:11038657
poikiloderma with neutropenia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Usb1 U6 snRNA biogenesis phosphodiesterase 1 JBrowse link 19 10,105,750 10,118,701 RGD:8554872
RGD:7240710
Severe Chronic Neutropenia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Csf3r colony stimulating factor 3 receptor JBrowse link 5 144,031,353 144,051,966 RGD:10450484
severe congenital neutropenia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Csf3r colony stimulating factor 3 receptor JBrowse link 5 144,031,353 144,051,966 RGD:10450485
RGD:8554872
RGD:10450533
G Elane elastase, neutrophil expressed JBrowse link 7 12,638,320 12,640,168 RGD:1598891
RGD:8554872
RGD:10450525
RGD:10450519
RGD:10450514
G G6pc3 glucose 6 phosphatase catalytic subunit 3 JBrowse link 10 90,134,193 90,138,425 RGD:8554872
G Gfi1 growth factor independent 1 transcriptional repressor JBrowse link 14 3,058,035 3,073,332 RGD:8554872
RGD:13592920
G Hax1 HCLS1 associated protein X-1 JBrowse link 2 189,330,900 189,333,305 RGD:8554872
G Jagn1 jagunal homolog 1 JBrowse link 4 145,399,885 145,404,605 RGD:8554872
G Tcirg1 T-cell immune regulator 1, ATPase H+ transporting V0 subunit A3 JBrowse link 1 219,126,687 219,139,466 RGD:8554872
severe congenital neutropenia 1 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Elane elastase, neutrophil expressed JBrowse link 7 12,638,320 12,640,168 RGD:7240710
RGD:8554872
G Tcirg1 T-cell immune regulator 1, ATPase H+ transporting V0 subunit A3 JBrowse link 1 219,126,687 219,139,466 RGD:8554872
Severe Congenital Neutropenia, Autosomal Dominant 2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gfi1 growth factor independent 1 transcriptional repressor JBrowse link 14 3,058,035 3,073,332 RGD:7240710
RGD:8554872
Severe Congenital Neutropenia, Autosomal Dominant 8 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Efl1 elongation factor like GTPase 1 JBrowse link 1 144,601,425 144,740,634 RGD:8554872
G Srp54a signal recognition particle 54A JBrowse link 6 75,996,629 76,035,768 RGD:8554872
RGD:7240710
Severe Congenital Neutropenia, Autosomal Recessive 3 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hax1 HCLS1 associated protein X-1 JBrowse link 2 189,330,900 189,333,305 RGD:7240710
RGD:8554872
G Vps45 vacuolar protein sorting 45 homolog JBrowse link 2 198,123,747 198,184,739 RGD:11554173
Severe Congenital Neutropenia, Autosomal Recessive 4 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G G6pc3 glucose 6 phosphatase catalytic subunit 3 JBrowse link 10 90,134,193 90,138,425 RGD:7240710
RGD:8554872
Severe Congenital Neutropenia, Autosomal Recessive, 5 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Vps45 vacuolar protein sorting 45 homolog JBrowse link 2 198,123,747 198,184,739 RGD:7240710
RGD:8554872
Severe Congenital Neutropenia, Autosomal Recessive, 6 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Jagn1 jagunal homolog 1 JBrowse link 4 145,399,885 145,404,605 RGD:8554872
RGD:11531099
RGD:11531098
RGD:7240710
Severe Congenital Neutropenia, Autosomal Recessive, 7 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Csf3r colony stimulating factor 3 receptor JBrowse link 5 144,031,353 144,051,966 RGD:8554872
RGD:7240710
Severe Congenital Neutropenia, X-Linked term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Elane elastase, neutrophil expressed JBrowse link 7 12,638,320 12,640,168 RGD:8554872
G Was WASP actin nucleation promoting factor JBrowse link X 15,155,246 15,164,099 RGD:7240710
RGD:8554872
RGD:11554173
X-Linked Anemia with or without Neutropenia and/or Platelet Abnormalities term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gata1 GATA binding protein 1 JBrowse link X 15,273,937 15,281,759 RGD:8554872
RGD:7240710
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15608
    disease of anatomical entity 14965
      hematopoietic system disease 1541
        leukocyte disease 532
          leukopenia 114
            agranulocytosis 58
              Acquired Agranulocytosis + 24
              Granulocytopenia with Immunoglobulin Abnormality 0
              neutropenia + 55
Path 2
Term Annotations click to browse term
  disease 15608
    disease of anatomical entity 14965
      Hemic and Lymphatic Diseases 1896
        hematopoietic system disease 1541
          leukocyte disease 532
            leukopenia 114
              agranulocytosis 58
                Acquired Agranulocytosis + 24
                Granulocytopenia with Immunoglobulin Abnormality 0
                neutropenia + 55
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.