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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:thromboangiitis obliterans
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Accession:DOID:12918 term browser browse the term
Definition:A non-atherosclerotic, inflammatory thrombotic disease that commonly involves small and medium-sized arteries or veins in the extremities. It is characterized by occlusive THROMBOSIS and FIBROSIS in the vascular wall leading to digital and limb ISCHEMIA and ulcerations. Thromboangiitis obliterans is highly associated with tobacco smoking.
Synonyms:exact_synonym: Buerger disease;   Buerger's disease;   Buergers disease;   presenile gangrene;   thromboangitis obliterans
 primary_id: MESH:D013919
 alt_id: OMIM:211480;   RDO:0006689
 xref: ICD10CM:I73.1;   ICD9CM:443.1;   NCI:C35070
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
 
thromboangiitis obliterans term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor treatment IEP
IDA
mRNA, protein:increased expression:femoral artery (rat) RGD PMID:23069071, PMID:23069071 RGD:7207785, RGD:7207785 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 IEP mRNA:increased expression:femoral artery (rat) RGD PMID:19572944 RGD:5508315 NCBI chr10:92,191,473...92,233,662
Ensembl chr10:92,191,718...92,232,645
JBrowse link
G Eln elastin ISO protein:increased expression:blood: RGD PMID:8763587 RGD:9585753 NCBI chr12:24,978,478...25,021,864
Ensembl chr12:24,978,483...25,021,863
JBrowse link
G Ucn urocortin IEP
IDA
mRNA:increased expression:femoral artery (rat) RGD PMID:19572944, PMID:19572944 RGD:5508315, RGD:5508315 NCBI chr 6:26,602,144...26,602,974
Ensembl chr 6:26,602,144...26,602,974
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 ISO
IEP
protein:increased expression:femoral artery: RGD PMID:12086338, PMID:23069071 RGD:1580352, RGD:7207785 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16929
    disease of anatomical entity 16296
      cardiovascular system disease 4404
        vascular disease 3326
          peripheral vascular disease 252
            thromboangiitis obliterans 5
paths to the root