Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:thromboangiitis obliterans
go back to main search page
Accession:DOID:12918 term browser browse the term
Definition:A non-atherosclerotic, inflammatory thrombotic disease that commonly involves small and medium-sized arteries or veins in the extremities. It is characterized by occlusive THROMBOSIS and FIBROSIS in the vascular wall leading to digital and limb ISCHEMIA and ulcerations. Thromboangiitis obliterans is highly associated with tobacco smoking.
Synonyms:exact_synonym: Buerger disease;   Buerger's disease;   Buergers disease;   presenile gangrene;   thromboangitis obliterans
 primary_id: MESH:D013919
 alt_id: OMIM:211480
 xref: EFO:1001211;   ICD10CM:I73.1;   ICD9CM:443.1;   NCI:C35070
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
thromboangiitis obliterans term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGER advanced glycosylation end-product specific receptor treatment ISO mRNA, protein:increased expression:femoral artery (rat) RGD PMID:23069071 PMID:23069071 RGD:7207785, RGD:7207785 NCBI chr 6:32,180,969...32,184,253
Ensembl chr 6:32,180,968...32,184,322 		JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 ISO mRNA:increased expression:femoral artery (rat) RGD PMID:19572944 RGD:5508315 NCBI chr17:45,784,320...45,835,828
Ensembl chr17:45,784,277...45,835,828 		JBrowse link
G ELN elastin IEP protein:increased expression:blood: RGD PMID:8763587 RGD:9585753 NCBI chr 7:74,028,173...74,069,907
Ensembl chr 7:74,027,789...74,069,907 		JBrowse link
G HLA-A major histocompatibility complex, class I, A susceptibility IAGP DNA:polymorphisms,haplotypes::HLA���A*03:01,HLA���A*29:01 (human) RGD PMID:32567246 RGD:401827144 NCBI chr 6:29,942,532...29,945,870
Ensembl chr 6:29,941,260...29,949,572 		JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 susceptibility IAGP DNA:polymorphisms, haplotype: :HLA���DRB1*04:02, HLA���DRB1*16:01, HLA���DRB1*01:01 (human) RGD PMID:32567246 RGD:401827144 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848 		JBrowse link
G UCN urocortin ISO mRNA:increased expression:femoral artery (rat) RGD PMID:19572944 RGD:5508315 NCBI chr 2:27,307,400...27,308,445
Ensembl chr 2:27,307,400...27,308,445 		JBrowse link
G VCAM1 vascular cell adhesion molecule 1 IEP
ISO		 protein:increased expression:femoral artery: RGD PMID:12086338 PMID:23069071 RGD:1580352, RGD:7207785 NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 41189
    disease of anatomical entity 32344
      cardiovascular system disease 6065
        vascular disease 3857
          peripheral vascular disease 423
            thromboangiitis obliterans 7
paths to the root