Send us a Message

Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   


RGD uses the Human Disease Ontology (DO, for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:acute kidney tubular necrosis
go back to main search page
Accession:DOID:12556 term browser browse the term
Definition:An acute kidney failure that is characterized by necrosis of epithelial tubule cells. (DO)
Synonyms:exact_synonym: ATN - acute tubular necrosis;   Lower Nephron Nephroses;   Lower Nephron Nephrosis;   acute renal failure with lesion of tubular necrosis;   acute renal failure with tubular necrosis;   acute tubular necrosis;   acute tubule necrosis
 primary_id: MESH:D007683
 xref: EFO:1000794;   ICD10CM:N17.0;   NCI:C34749
For additional species annotation, visit the Alliance of Genome Resources.

show annotations for term's descendants           Sort by:
acute kidney tubular necrosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AK4 adenylate kinase 4 ISO protein:decreased expression:kidney (rat) RGD PMID:21152904 RGD:5134352 NCBI chr 6:147,177,029...147,257,799
Ensembl chr 6:147,177,029...147,257,814
JBrowse link
G BMP7 bone morphogenetic protein 7 ISO associated with Kidney Reperfusion Injury;protein:increased expression:kidney RGD PMID:16284088 RGD:1601494 NCBI chr17:57,567,770...57,676,516
Ensembl chr17:57,584,956...57,675,986
JBrowse link
G CCT7 chaperonin containing TCP1 subunit 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31825490 NCBI chr 3:69,527,238...69,540,489
Ensembl chr 3:69,526,534...69,546,548
JBrowse link
G CIITA class II major histocompatibility complex transactivator ISO mRNA:increased expression:kidney RGD PMID:9422398 RGD:7242901 NCBI chr 3:32,171,706...32,230,775
Ensembl chr 3:32,172,214...32,230,780
JBrowse link
G FABP1 fatty acid binding protein 1 ISO CTD Direct Evidence: therapeutic CTD PMID:18368030 NCBI chr 3:57,850,511...57,854,966
Ensembl chr 3:57,850,499...57,854,956
JBrowse link
G GSR glutathione-disulfide reductase ISO protein:decreased activity:renal cortex: RGD PMID:12885594 PMID:17078987 RGD:7257555 RGD:7257573 NCBI chr15:54,382,564...54,433,989
Ensembl chr15:54,382,567...54,433,984
JBrowse link
G HAVCR1 hepatitis A virus cellular receptor 1 ISO protein:increased expression:kidney tubule, urine: RGD PMID:12081583 RGD:7245970 NCBI chr16:66,162,318...66,208,868 JBrowse link
G NOG noggin ISO associated with Kidney Reperfusion Injury RGD PMID:16284088 RGD:1601494 NCBI chr12:32,891,321...32,892,206
Ensembl chr12:32,891,321...32,892,206
JBrowse link
G POMC proopiomelanocortin ISO CTD Direct Evidence: marker/mechanism CTD PMID:4358912 PMID:6254450 NCBI chr 3:113,661,712...113,668,558
Ensembl chr 3:113,661,004...113,670,418
JBrowse link
G PPARA peroxisome proliferator activated receptor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:19834340 NCBI chr 5:3,302,755...3,321,091
Ensembl chr 5:3,300,741...3,364,239
JBrowse link
G SOD2 superoxide dismutase 2 ISO CTD Direct Evidence: therapeutic CTD PMID:19917352 NCBI chr 1:7,679,352...7,689,564
Ensembl chr 1:7,679,352...7,689,560
JBrowse link
G TEK TEK receptor tyrosine kinase ISO associated with Kidney Reperfusion Injury RGD PMID:16284088 RGD:1601494 NCBI chr 1:195,938,177...196,052,294
Ensembl chr 1:195,937,432...196,051,980
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14553
    disease of anatomical entity 14263
      Urogenital Diseases 4217
        urinary system disease 1982
          kidney disease 1761
            kidney failure 475
              acute kidney failure 281
                acute kidney tubular necrosis 12
paths to the root