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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:hepatitis A
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Accession:DOID:12549 term browser browse the term
Definition:INFLAMMATION of the LIVER in humans caused by a member of the HEPATOVIRUS genus, HUMAN HEPATITIS A VIRUS. It can be transmitted through fecal contamination of food or water.
Synonyms:exact_synonym: Infectious Hepatitides;   Infectious Hepatitis;   Viral hepatitis, type A
 related_synonym: Viral hepatitis A
 primary_id: MESH:D006506;   RDO:0005776
 xref: NCI:C3096
For additional species annotation, visit the Alliance of Genome Resources.

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hepatitis A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme ISO DNA:insertion/deletion:intron 16: RGD PMID:12458570 RGD:39939119 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 disease_progression ISO RGD PMID:26347518 RGD:40818419 NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963 		JBrowse link
G Pdcd1 programmed cell death 1 disease_progression ISO RGD PMID:26347518 RGD:40818419 NCBI chr 9:94,418,786...94,431,945
Ensembl chr 9:94,418,791...94,431,937 		JBrowse link
G Tnf tumor necrosis factor ISO protein:increased expression:serum (human) RGD PMID:9047083 RGD:14995307 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 susceptibility ISO DNA:missense mutation:cds:p.R194W (rs1799782) (human)
DNA:SNP:intron: (rs1001581) (human)		 RGD PMID:22135187 PMID:29558945 RGD:15014793, RGD:15036793 NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17205
    disease by infectious agent 1916
      viral infectious disease 1569
        hepatitis A 5
Path 2
Term Annotations click to browse term
  disease 17205
    disease of anatomical entity 16551
      gastrointestinal system disease 6061
        hepatobiliary disease 2559
          liver disease 2462
            hepatitis 271
              viral hepatitis 191
                Human Viral Hepatitis 188
                  hepatitis A 5
paths to the root