RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: malaria
Accession: DOID:12365
browse the term
Definition: A parasitic protozoa infectious disease characterized as a vector-borne infectious disease caused by the presence of protozoan parasites of the genus Plasmodium in the red blood cells, transmitted from an infected to an uninfected individual by the bite of anopheline mosquitoes, and characterized by periodic attacks of chills and fever that coincide with mass destruction of blood cells and the release of toxic substances by the parasite at the end of each reproductive cycle. (DO)
Synonyms: exact_synonym: MALS; Marsh Fever; Paludism; Plasmodium Infection; Plasmodium Infections; induced malaria; remittent fever
related_synonym: DUFFY BLOOD GROUP SYSTEM, FY(a-b-) PHENOTYPE; Glycophorin C, Gerbich Variant; MALARIA, CEREBRAL, RESISTANCE TO; MALARIA, CEREBRAL, SUSCEPTIBILITY TO; MALARIA, MILD, SUSCEPTIBILITY TO; MALARIA, RESISTANCE TO; MALARIA, SEVERE, RESISTANCE TO; MALARIA, SEVERE, SUSCEPTIBILITY TO; plasmodium vivax, resistance to; susceptibility to malaria
primary_id: MESH:D008288
alt_id: OMIM:609148 ; OMIM:611162
xref: EFO:0001068 ; EFO:0009157 ; GARD:6961 ; ICD10CM:B54 ; ICD9CM:084 ; NCI:C34797
For additional species annotation, visit the
Alliance of Genome Resources .
GViewer not supported for the selected species.
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Abcb1
ATP binding cassette subfamily B member 1
susceptibility treatment
ISO
DNA:SNPs,haplotype: :rs2032582, rs1128503 (human) DNA:SNP: :c3435C>T(human) DNA:haplotype: :1236C>T, 2677G>T,3435C>T (human) DNA:hypermethylation:promoter
RGD
PMID:17015054 PMID:19331170 PMID:28422980 PMID:28934955
RGD:39456120 RGD:39456123 RGD:39457679 RGD:39457680
NCBI chrNW_004936763:1,225,355...1,308,257
Ensembl chrNW_004936763:1,226,482...1,297,427
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Ackr1
atypical chemokine receptor 1 (Duffy blood group)
ISO
ClinVar Annotator: match by term: Plasmodium vivax, resistance to
ClinVar OMIM
PMID:7663520 PMID:8547665 PMID:8651934 PMID:10570183 PMID:10791881 PMID:17304246 PMID:18179887 PMID:18621010 PMID:19180233 PMID:19620399 PMID:20932074 More...
NCBI chrNW_004936740:1,295,299...1,298,441
Ensembl chrNW_004936740:1,295,319...1,296,812
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Aicda
activation induced cytidine deaminase
ISO
protein:increased expression: B cell
RGD
PMID:27980783
RGD:30310233
NCBI chrNW_004936870:25,039...34,601
Ensembl chrNW_004936870:25,039...34,601
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Ank1
ankyrin 1
ISO
OMIM:609148 | OMIM:611162
MouseDO
NCBI chrNW_004936785:738,323...944,734
Ensembl chrNW_004936785:738,317...942,381
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Apoe
apolipoprotein E
ISO
DNA:missense mutations:cds:p.C112R, p.C158R (human)
RGD
PMID:24116184
RGD:11039486
NCBI chrNW_004936706:1,512,438...1,516,805
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Aqp4
aquaporin 4
ISO
OMIM:609148 | OMIM:611162
MouseDO
NCBI chrNW_004936550:5,931,201...5,943,999
Ensembl chrNW_004936550:5,931,194...5,941,354
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Cbs
cystathionine beta-synthase
susceptibility
ISO
DNA:insertion:cds: (844ins68) (human)
RGD
PMID:27198213
RGD:40903062
NCBI chrNW_004936500:976,043...1,003,559
Ensembl chrNW_004936500:987,128...1,003,388
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Cd36
CD36 molecule
ISO
ClinVar Annotator: match by term: Malaria, cerebral, susceptibility to | ClinVar Annotator: match by term: Malaria, susceptibility to
ClinVar OMIM
PMID:10890433 PMID:18305138 PMID:19403559 PMID:25741868
NCBI chrNW_004936810:791,823...838,303
Ensembl chrNW_004936810:758,182...838,365
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Cd40
CD40 molecule
severity
ISO
RGD
PMID:11485931
RGD:11352239
NCBI chrNW_004936514:6,936,915...6,947,246
Ensembl chrNW_004936514:6,936,572...6,947,280
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Cd40lg
CD40 ligand
severity
ISO
RGD
PMID:11485931
RGD:11352239
NCBI chrNW_004936513:10,607,617...10,620,403
Ensembl chrNW_004936513:10,607,617...10,620,403
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Cish
cytokine inducible SH2 containing protein
susceptibility
ISO
ClinVar Annotator: match by term: Malaria, susceptibility to
OMIM ClinVar
PMID:20484391
NCBI chrNW_004936529:2,116,786...2,124,469
Ensembl chrNW_004936529:2,118,325...2,124,684
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Crp
C-reactive protein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:8730300
NCBI chrNW_004936740:885,855...888,854
Ensembl chrNW_004936740:883,272...890,606
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Ctla4
cytotoxic T-lymphocyte associated protein 4
treatment disease_progression
ISO
RGD
PMID:28892065
RGD:38455986
NCBI chrNW_004936631:484,356...489,643
Ensembl chrNW_004936631:484,356...489,643
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Ephb2
EPH receptor B2
ISO
mRNA:increased expression:liver
RGD
PMID:25784101
RGD:127285023
NCBI chrNW_004936474:8,109,800...8,203,106
Ensembl chrNW_004936474:8,109,031...8,203,106
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Ephb3
EPH receptor B3
ISO
RGD
PMID:25784101
RGD:127285023
NCBI chrNW_004936578:5,286,580...5,297,369
Ensembl chrNW_004936578:5,287,340...5,298,142
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Ephb6
EPH receptor B6
ISO
RGD
PMID:25784101
RGD:127285023
NCBI chrNW_004936527:330,034...345,166
Ensembl chrNW_004936527:329,990...345,167
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Fcgr2a
Fc fragment of IgG receptor IIa
susceptibility
ISO
ClinVar Annotator: match by term: Malaria, severe, susceptibility to
OMIM ClinVar
PMID:8636449 PMID:9843982 PMID:10675363 PMID:15367919 PMID:19915573 PMID:19965803 PMID:24033266 More...
NCBI chrNW_004937131:15,542...22,099
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Fcgr2b
Fc fragment of IgG receptor IIb
susceptibility
ISO
ClinVar Annotator: match by term: Malaria, resistance to
OMIM ClinVar
PMID:12115230 PMID:15459183 PMID:16115811 PMID:16170323 PMID:17435165 PMID:20385827 More...
NCBI chrNW_004937131:80,014...96,114
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Foxp3
forkhead box P3
disease_progression
ISO
RGD
PMID:16169501 PMID:19338000
RGD:38455985 RGD:38455992
NCBI chrNW_004936721:1,118,376...1,125,282
Ensembl chrNW_004936721:1,118,782...1,132,308
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G6pd
glucose-6-phosphate dehydrogenase
severity susceptibility
ISO
DNA:point mutation:cds:c.968T>C (human) DNA:SNPs: :multiple ClinVar Annotator: match by term: Malaria, susceptibility to
RGD OMIM ClinVar
PMID:5448 PMID:16832 PMID:1303173 PMID:1459579 PMID:1551674 PMID:1562739 PMID:1631957 PMID:1805484 PMID:1924316 PMID:1945893 PMID:1953767 PMID:1972698 PMID:1978554 PMID:1978555 PMID:2253938 PMID:2263506 PMID:2321910 PMID:2393028 PMID:2503817 PMID:2572288 PMID:2633878 PMID:2836867 PMID:2849540 PMID:2912069 PMID:3198117 PMID:3338798 PMID:3393536 PMID:3446582 PMID:4283789 PMID:4359638 PMID:4379606 PMID:4388132 PMID:4392654 PMID:4435794 PMID:4721339 PMID:4837298 PMID:4974311 PMID:5081671 PMID:5305539 PMID:5369703 PMID:5485383 PMID:5641629 PMID:5673160 PMID:5770172 PMID:5844610 PMID:6015571 PMID:6698555 PMID:6714986 PMID:7203486 PMID:7327562 PMID:7390473 PMID:7440223 PMID:7577654 PMID:7590755 PMID:7789945 PMID:7803800 PMID:7806085 PMID:7825590 PMID:7947239 PMID:7947250 PMID:7949118 PMID:7959686 PMID:8118045 PMID:8193373 PMID:8244337 PMID:8370579 PMID:8447319 PMID:8471773 PMID:8490627 PMID:8537082 PMID:8611726 PMID:8807321 PMID:8860013 PMID:8956035 PMID:9017974 PMID:9192788 PMID:9233561 PMID:9250351 PMID:9342374 PMID:9589612 PMID:9858856 PMID:10221015 PMID:10502785 PMID:10643148 PMID:10734064 PMID:10782016 PMID:11024211 PMID:11146567 PMID:11243133 PMID:11400791 PMID:11445808 PMID:11499668 PMID:11601226 PMID:11793482 PMID:12028056 PMID:12064920 PMID:12105841 PMID:12367584 PMID:12497642 PMID:12737938 PMID:12768444 PMID:14014720 PMID:14278484 PMID:14505231 PMID:15223006 PMID:15315792 PMID:15349799 PMID:15502081 PMID:15625830 PMID:15727905 PMID:15766741 PMID:15906717 PMID:16088936 PMID:16119988 PMID:16136268 PMID:16143877 PMID:16155737 PMID:16329560 PMID:16356170 PMID:16513531 PMID:16528451 PMID:16607506 PMID:16777444 PMID:16927025 PMID:17587269 PMID:17726510 PMID:17959407 PMID:18046504 PMID:18226470 PMID:18270558 PMID:18329300 PMID:18452027 PMID:18568599 PMID:19589177 PMID:19594365 PMID:20007901 PMID:20200584 PMID:20203002 PMID:20236109 PMID:20602793 PMID:21446359 PMID:21479984 PMID:21507207 PMID:21637675 PMID:21677401 PMID:21874587 PMID:21931771 PMID:21989994 PMID:22018328 PMID:22164279 PMID:22165289 PMID:22171972 PMID:22293322 PMID:22307442 PMID:22452742 PMID:22552160 PMID:22770933 PMID:22906047 PMID:22906837 PMID:22963789 PMID:23006493 PMID:23144702 PMID:23479361 PMID:23926329 PMID:23965028 PMID:24033266 PMID:24134566 PMID:24460025 PMID:24551785 PMID:24586352 PMID:24615128 PMID:25015414 PMID:25071003 PMID:25201310 PMID:25326637 PMID:25440321 PMID:25536053 PMID:25541721 PMID:25548459 PMID:25741868 PMID:25775246 PMID:26060661 PMID:26226515 PMID:26633385 PMID:26823837 PMID:26990548 PMID:27053284 PMID:27213370 PMID:27287612 PMID:27519946 PMID:27535533 PMID:27853304 PMID:27880809 PMID:27884173 PMID:27980749 PMID:28195434 PMID:28492532 PMID:28852037 PMID:29072585 PMID:29141760 PMID:29300386 PMID:29339739 PMID:30045279 PMID:30077011 PMID:30096395 PMID:30161219 PMID:30314477 PMID:30315739 PMID:30674319 PMID:31489982 PMID:31525211 PMID:31862010 PMID:31863082 PMID:32180910 PMID:32425388 PMID:32860008 PMID:33051526 PMID:33072997 PMID:33413378 PMID:33636823 PMID:34620237 PMID:34659341 PMID:34762759 PMID:34895177 PMID:34934109 PMID:34966093 PMID:35313968 PMID:35840819 More...
RGD:10449111 RGD:10449115
NCBI chrNW_004936809:1,269,900...1,285,853
Ensembl chrNW_004936809:1,269,914...1,285,889
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Gypa
glycophorin A (MNS blood group)
ISO
OMIM
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Gypc
glycophorin C (Gerbich blood group)
ISO
ClinVar Annotator: match by term: Malaria, resistance to
ClinVar OMIM
PMID:1991173 PMID:5011657 PMID:8157284 PMID:11719395 PMID:12469115 PMID:21061946 More...
NCBI chrNW_004936469:44,526,679...44,561,549
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Hmox1
heme oxygenase 1
ISO
OMIM:609148 | OMIM:611162
MouseDO
NCBI chrNW_004936492:5,042,353...5,049,216
Ensembl chrNW_004936492:5,042,330...5,049,311
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Icam1
intercellular adhesion molecule 1
susceptibility
ISO
ClinVar Annotator: match by term: Malaria, cerebral, susceptibility to | ClinVar Annotator: match by term: Malaria, susceptibility to
OMIM ClinVar
PMID:9259284 PMID:9861406 PMID:10417733 PMID:10699175 PMID:23609612 PMID:25741868 More...
NCBI chrNW_004936659:616,570...627,172
Ensembl chrNW_004936659:616,752...627,174
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Ifng
interferon gamma
ISO
OMIM:609148 | OMIM:611162
MouseDO
NCBI chrNW_004936545:6,139,130...6,144,543
Ensembl chrNW_004936545:6,139,116...6,148,452
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Ikbkg
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
ISO
ClinVar Annotator: match by term: Malaria, susceptibility to
ClinVar
PMID:1945893 PMID:3198117 PMID:7803800 PMID:8244337 PMID:8471773 PMID:9589612 PMID:10502785 PMID:11601226 PMID:12064920 PMID:15727905 PMID:16329560 PMID:16607506 PMID:25741868 PMID:28492532 PMID:29300386 PMID:29339739 PMID:30045279 PMID:30315739 PMID:31489982 PMID:31863082 PMID:33051526 PMID:33072997 PMID:34659341 PMID:34762759 PMID:34895177 PMID:35313968 PMID:35840819 More...
NCBI chrNW_004936809:1,280,254...1,306,964
Ensembl chrNW_004936809:1,257,654...1,301,813
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Il1rl1
interleukin 1 receptor like 1
ISO
RGD
PMID:28359899
RGD:39938859
NCBI chrNW_004936713:1,020,969...1,035,012
Ensembl chrNW_004936713:1,021,044...1,035,039
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Il21
interleukin 21
exacerbates
ISO
RGD
PMID:25763578
RGD:127285358
NCBI chrNW_004936662:1,689,879...1,696,883
Ensembl chrNW_004936662:1,689,879...1,696,883
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Il27
interleukin 27
ameliorates
ISO
RGD
PMID:24522137 PMID:26968425
RGD:11530371 RGD:126790512
NCBI chrNW_004936501:11,972,715...11,978,152
Ensembl chrNW_004936501:11,973,385...11,976,583
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Il33
interleukin 33
ISO
protein:increased expression:serum:
RGD
PMID:28359899
RGD:39938859
NCBI chrNW_004936539:763,755...791,461
Ensembl chrNW_004936539:623,248...791,470
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LOC101964865
complement receptor type 1
ISO
ClinVar Annotator: match by term: Malaria, severe, resistance to | ClinVar Annotator: match by term: Malaria, susceptibility to
ClinVar OMIM
PMID:10528197 PMID:14694201 PMID:20855594 PMID:25741868
NCBI chrNW_004936557:5,185,831...5,284,999
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LOC101968921
angiotensin-converting enzyme
severity
ISO
RGD
PMID:31234939
RGD:39939120
NCBI chrNW_004936541:4,157,847...4,178,156
Ensembl chrNW_004936541:4,157,393...4,178,177
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LOC101976500
haptoglobin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:8730300 PMID:16597321
NCBI chrNW_004936475:21,841,054...21,845,821
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Ltbr
lymphotoxin beta receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:15788153
NCBI chrNW_004936709:1,362,846...1,369,287
Ensembl chrNW_004936709:1,362,840...1,369,365
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Mapkapk3
MAPK activated protein kinase 3
ISO
ClinVar Annotator: match by term: Malaria, susceptibility to
ClinVar
PMID:20484391
NCBI chrNW_004936529:2,130,421...2,159,859
Ensembl chrNW_004936529:2,130,252...2,160,313
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Mki67
marker of proliferation Ki-67
ISO
associated with Lung Neoplasms
RGD
PMID:21931708
RGD:6483517
NCBI chrNW_004936486:15,561,327...15,587,109
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Ncr3
natural cytotoxicity triggering receptor 3
susceptibility
ISO
ClinVar Annotator: match by term: Malaria, severe, susceptibility to
OMIM ClinVar
PMID:17208487
NCBI chrNW_004936727:1,921,452...1,924,395
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Nos2
nitric oxide synthase 2
ISO
ClinVar Annotator: match by term: Malaria, resistance to | ClinVar Annotator: match by term: Malaria, severe, resistance to | ClinVar Annotator: match by term: Malaria, susceptibility to
ClinVar OMIM
PMID:9457101 PMID:12433515 PMID:31995689
NCBI chrNW_004936538:4,052,277...4,097,051
Ensembl chrNW_004936538:4,052,448...4,097,051
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Pklr
pyruvate kinase L/R
susceptibility
ISO
DNA:missense mutation:cds:p.I90N (mouse) OMIM:609148 | OMIM:611162 DNA:mutations, haplotype:multiple (human)
RGD MouseDO
PMID:14595440 PMID:20377593
RGD:11535999 RGD:11537407
NCBI chrNW_004936580:4,770,977...4,799,316
Ensembl chrNW_004936580:4,767,109...4,779,916
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Prf1
perforin 1
ISO
RGD
PMID:21525386
RGD:6482803
NCBI chrNW_004936521:8,057,874...8,060,695
Ensembl chrNW_004936521:8,057,874...8,060,695
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Procr
protein C receptor
disease_progression
ISO
RGD
PMID:27671831
RGD:126848795
NCBI chrNW_004936561:5,557,640...5,562,981
Ensembl chrNW_004936561:5,557,630...5,563,030
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Slc19a1
solute carrier family 19 member 1
ISO
DNA:SNP::g.80G>A (human)
RGD
PMID:27198213
RGD:40903062
NCBI chrNW_004936778:823,376...846,843
Ensembl chrNW_004936778:829,550...848,833
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Slc4a1
solute carrier family 4 member 1 (Diego blood group)
ISO
ClinVar Annotator: match by term: Malaria, cerebral, resistance to | ClinVar Annotator: match by term: Malaria, susceptibility to
ClinVar
PMID:1378323 PMID:1722314 PMID:1737855 PMID:2146504 PMID:6338046 PMID:7689982 PMID:7919393 PMID:7949112 PMID:8434259 PMID:8704215 PMID:9207478 PMID:9312167 PMID:9854053 PMID:10403343 PMID:10926824 PMID:10942416 PMID:12087557 PMID:12750988 PMID:12938018 PMID:14618420 PMID:16107207 PMID:16420521 PMID:17215882 PMID:18266205 PMID:19229254 PMID:19289107 PMID:19625994 PMID:20068363 PMID:20151848 PMID:20421175 PMID:20799361 PMID:22126643 PMID:22518001 PMID:22609520 PMID:23255290 PMID:24652967 PMID:25741868 PMID:28045035 PMID:28188436 PMID:28233610 PMID:28492532 PMID:28542241 PMID:29627839 PMID:30192042 PMID:30230413 PMID:31147440 PMID:31672324 PMID:31959358 PMID:32071839 PMID:33532864 PMID:35738466 More...
NCBI chrNW_004936541:718,577...727,420
Ensembl chrNW_004936541:718,577...729,876
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Spp1
secreted phosphoprotein 1
ISO
RGD
PMID:16552072
RGD:1581333
NCBI chrNW_004936905:148,956...156,023
Ensembl chrNW_004936905:148,945...156,079
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Tbx21
T-box transcription factor 21
ISO
RGD
PMID:19338000
RGD:38455985
NCBI chrNW_004936490:13,546,405...13,558,635
Ensembl chrNW_004936490:13,546,292...13,558,635
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Tirap
TIR domain containing adaptor protein
ISO
ClinVar Annotator: match by term: Malaria, resistance to
ClinVar OMIM
PMID:16991088 PMID:17322885 PMID:18305471 PMID:25741868
NCBI chrNW_004936572:5,926,193...5,938,621
Ensembl chrNW_004936572:5,924,158...5,938,658
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Tnf
tumor necrosis factor
susceptibility
ISO
ClinVar Annotator: match by term: Malaria, cerebral, susceptibility to
OMIM ClinVar
PMID:8056188 PMID:9818939 PMID:10369255 PMID:10450718 PMID:11261930 PMID:11506397 PMID:11826025 PMID:11896460 PMID:12485196 PMID:12746914 PMID:12759288 PMID:14681301 PMID:14718719 PMID:16418737 PMID:16720636 PMID:16865291 PMID:16909270 PMID:18050183 PMID:18713756 PMID:19365401 PMID:22760475 PMID:22992668 More...
NCBI chrNW_004936727:1,936,066...1,937,766
Ensembl chrNW_004936727:1,936,066...1,937,766
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Trem1
triggering receptor expressed on myeloid cells 1
severity
ISO
DNA:SNP: :rs2234237A>T (human)
RGD
PMID:27671831
RGD:126848795
NCBI chrNW_004936476:18,577,825...18,583,675
Ensembl chrNW_004936476:18,574,381...18,583,647
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Tslp
thymic stromal lymphopoietin
ISO
mRNA:altered expression:multiple (mouse)
RGD
PMID:28955823
RGD:38596344
NCBI chrNW_004936531:5,495,872...5,500,462
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Ace2
angiotensin converting enzyme 2
susceptibility
ISO
DNA:SNP:intron 1: C>T
RGD
PMID:20117248
RGD:40818420
NCBI chrNW_004936470:4,964,526...5,011,808
Ensembl chrNW_004936470:4,965,332...5,011,702
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Aqp4
aquaporin 4
disease_progression
ISO
protein:increased expression:astrocyte:
RGD
PMID:21904632
RGD:8698661
NCBI chrNW_004936550:5,931,201...5,943,999
Ensembl chrNW_004936550:5,931,194...5,941,354
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Cast
calpastatin
ISO
protein:increased express:brain
RGD
PMID:16236382
RGD:5509817
NCBI chrNW_004936523:6,688,153...6,798,184
Ensembl chrNW_004936523:6,686,519...6,798,321
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Cd36
CD36 molecule
ISO
RGD
PMID:17367535
RGD:6893527
NCBI chrNW_004936810:791,823...838,303
Ensembl chrNW_004936810:758,182...838,365
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Clec12a
C-type lectin domain family 12 member A
ameliorates
ISO
RGD
PMID:31269448
RGD:41412201
NCBI chrNW_004936902:542,981...556,142
Ensembl chrNW_004936902:543,670...556,014
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Il1rl1
interleukin 1 receptor like 1
treatment
ISO
RGD
PMID:25682948
RGD:40400741
NCBI chrNW_004936713:1,020,969...1,035,012
Ensembl chrNW_004936713:1,021,044...1,035,039
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Il33
interleukin 33
treatment
ISO
protein:increased expression:brain
RGD
PMID:25659095 PMID:25682948
RGD:39938955 RGD:40400741
NCBI chrNW_004936539:763,755...791,461
Ensembl chrNW_004936539:623,248...791,470
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Jak3
Janus kinase 3
ISO
RGD
PMID:22363534
RGD:11531103
NCBI chrNW_004936596:3,212,593...3,224,426
Ensembl chrNW_004936596:3,212,593...3,224,048
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Lta
lymphotoxin alpha
ISO
RGD
PMID:12021316
RGD:10449455
NCBI chrNW_004936727:1,940,081...1,941,022
Ensembl chrNW_004936727:1,940,081...1,941,022
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Nrg1
neuregulin 1
treatment
ISO
mRNA, protein:increased expression:cerebral cortex (mouse) human protein in a mouse model
RGD
PMID:24433482 PMID:29636063
RGD:39456084 RGD:39456102
NCBI chrNW_004936766:1,104,841...1,306,368
Ensembl chrNW_004936766:1,104,728...1,305,972
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Pik3cg
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
ISO
RGD
PMID:25775137
RGD:38599200
NCBI chrNW_004936479:17,084,006...17,112,264
Ensembl chrNW_004936479:17,084,920...17,112,258
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Prkaa2
protein kinase AMP-activated catalytic subunit alpha 2
ISO
mRNA:decreased expression:brain (mouse)
RGD
PMID:29107705
RGD:39456137
NCBI chrNW_004936522:4,872,360...4,939,873
Ensembl chrNW_004936522:4,875,046...4,939,879
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Tnfrsf1b
TNF receptor superfamily member 1B
ISO
RGD
PMID:12228317
RGD:5131158
NCBI chrNW_004936474:908,414...935,765
Ensembl chrNW_004936474:908,485...934,177
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LOC101955076
low affinity immunoglobulin gamma Fc region receptor III-A
severity susceptibility
ISO
DNA:polymorphism: :p.F176V (human)
RGD
PMID:20231419 PMID:23045477
RGD:11040771 RGD:11344971
NCBI chrNW_004937131:42,523...49,533
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Slc4a1
solute carrier family 4 member 1 (Diego blood group)
severity
ISO
DNA:snp:promoter:g.-5699T>C (human)
RGD
PMID:16960783
RGD:10450507
NCBI chrNW_004936541:718,577...727,420
Ensembl chrNW_004936541:718,577...729,876
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Abo
ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase
susceptibility
ISO
DNA:SNPs,haplotype:multiple
RGD
PMID:18003641
RGD:39938831
NCBI chrNW_004936570:1,315,192...1,322,719
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Adamts13
ADAM metallopeptidase with thrombospondin type 1 motif 13
ISO
protein:decreased activity:plasma (human)
RGD
PMID:20062916
RGD:10449041
NCBI chrNW_004936669:3,449,259...3,478,471
Ensembl chrNW_004936669:3,456,494...3,478,512
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Bsg
basigin (Ok blood group)
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:22080952 PMID:26195724
NCBI chrNW_004936588:181,688...189,795
Ensembl chrNW_004936588:181,576...189,287
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Cast
calpastatin
ISO
protein:alter localization:erythrocyte
RGD
PMID:17359359
RGD:5509812
NCBI chrNW_004936523:6,688,153...6,798,184
Ensembl chrNW_004936523:6,686,519...6,798,321
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Clec11a
C-type lectin domain containing 11A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19884328
NCBI chrNW_004936889:476,439...478,620
Ensembl chrNW_004936889:476,133...478,711
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Fas
Fas cell surface death receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21625619
NCBI chrNW_004936735:209,369...234,582
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Fcgr2a
Fc fragment of IgG receptor IIa
severity
ISO
DNA:missense mutation:cds:p.R131H (rs1801274) (human)
RGD
PMID:18194515
RGD:5147927
NCBI chrNW_004937131:15,542...22,099
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G6pd
glucose-6-phosphate dehydrogenase
severity
ISO
DNA:missense mutation:cds:202G>A (p.V68M) (human)
RGD
PMID:24943486
RGD:10449113
NCBI chrNW_004936809:1,269,900...1,285,853
Ensembl chrNW_004936809:1,269,914...1,285,889
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Gstp1
glutathione S-transferase pi 1
severity
ISO
RGD
PMID:19635899
RGD:10450848
NCBI chrNW_004936599:2,197,681...2,200,642
Ensembl chrNW_004936599:2,197,634...2,201,050
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Il13
interleukin 13
ISO
protein:increased expression:plasma
RGD
PMID:21985368
RGD:5684362
NCBI chrNW_004936647:2,529,933...2,532,503
Ensembl chrNW_004936647:2,530,491...2,532,373
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LOC101964865
complement receptor type 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:9230440 PMID:11724985
NCBI chrNW_004936557:5,185,831...5,284,999
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LOC101976500
haptoglobin
severity
ISO
DNA:missense mutation:cds:p.K54E (human)
RGD
PMID:24478401
RGD:11041793
NCBI chrNW_004936475:21,841,054...21,845,821
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Tnf
tumor necrosis factor
severity
ISO
protein:increased expression:plasma
RGD
PMID:1984482
RGD:10450571
NCBI chrNW_004936727:1,936,066...1,937,766
Ensembl chrNW_004936727:1,936,066...1,937,766
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Ackr1
atypical chemokine receptor 1 (Duffy blood group)
ISO
ClinVar Annotator: match by term: Resistance to Plasmodium vivax infection
OMIM ClinVar
PMID:7663520 PMID:8547665 PMID:8651934 PMID:10570183 PMID:10791881 PMID:17304246 PMID:18179887 PMID:18621010 PMID:19180233 PMID:19620399 PMID:20932074 More...
NCBI chrNW_004936740:1,295,299...1,298,441
Ensembl chrNW_004936740:1,295,319...1,296,812
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Il10
interleukin 10
ISO
RGD
PMID:24717969
RGD:11041890
NCBI chrNW_004936557:5,834,874...5,838,502
Ensembl chrNW_004936557:5,834,874...5,838,502
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