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Term:Vogt-Koyanagi-Harada disease
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Accession:DOID:12297 term browser browse the term
Definition:A syndrome characterized by bilateral granulomatous UVEITIS with IRITIS and secondary GLAUCOMA, premature ALOPECIA, symmetrical VITILIGO, poliosis circumscripta (a strand of depigmented hair), HEARING DISORDERS, and meningeal signs (neck stiffness and headache). Examination of the cerebrospinal fluid reveals a pattern consistent with MENINGITIS, ASEPTIC. (Adams et al., Principles of Neurology, 6th ed, p748; Surv Ophthalmol 1995 Jan;39(4):265-292)
Synonyms:exact_synonym: Harada's disease;   Uveomeningoencephalitis;   VKH Syndrome;   VKH Syndrome (Vogt Koyanagi Harada);   Vogt Koyanagi Harada syndrome;   Vogt-Koyanagi syndrome;   uveomeningoencephalitic syndrome;   uveomeningoencephalitides
 primary_id: MESH:D014607
 alt_id: RDO:0006798
 xref: GARD:7862;   ICD10CM:H20.82;   ICD10CM:H30.81;   ICD9CM:363.22;   ICD9CM:364.24;   NCI:C85218
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Vogt-Koyanagi-Harada disease term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:8142356
G Itgb2 integrin subunit beta 2 JBrowse link 20 11,777,773 11,815,647 RGD:6482200
G RT1-Ba RT1 class II, locus Ba JBrowse link 20 4,066,133 4,070,726 RGD:8547565
G RT1-Bb RT1 class II, locus Bb JBrowse link 20 4,043,726 4,049,367 RGD:7421525
G RT1-Db1 RT1 class II, locus Db1 JBrowse link 20 4,087,621 4,097,190 RGD:5147653
G Stat4 signal transducer and activator of transcription 4 JBrowse link 9 54,340,649 54,457,753 RGD:8661713
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:8142356

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Path 1
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  disease 15603
    syndrome 5215
      Vogt-Koyanagi-Harada disease 7
Path 2
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  disease 15603
    disease of anatomical entity 14934
      nervous system disease 10239
        sensory system disease 4697
          eye and adnexa disease 2259
            eye disease 2259
              uveal disease 219
                uveitis 133
                  Vogt-Koyanagi-Harada disease 7
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