Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:Lewy body dementia
go back to main search page
Accession:DOID:12217 term browser browse the term
Definition:A neurodegenerative disease characterized by dementia, mild parkinsonism, and fluctuations in attention and alertness. The neuropsychiatric manifestations tend to precede the onset of bradykinesia, MUSCLE RIGIDITY, and other extrapyramidal signs. DELUSIONS and visual HALLUCINATIONS are relatively frequent in this condition. Histologic examination reveals LEWY BODIES in the CEREBRAL CORTEX and BRAIN STEM. SENILE PLAQUES and other pathologic features characteristic of ALZHEIMER'S DISEASE may also be present. (From Neurology 1997;48:376-380; Neurology 1996;47:1113-1124)
Synonyms:exact_synonym: DLB;   Dementia with Lewy bodies;   Diffuse Lewy Body Disease;   Lewy Body Type Senile Dementia;   Lewy body disease;   cortical Lewy body disease;   senile dementia of the Lewy body type
 narrow_synonym: DIFFUSE LEWY BODY DISEASE DIFFUSE LEWY BODY DISEASE WITH GAZE PALSY;   LEWY BODY VARIANT OF ALZHEIMER DISEASE;   LEWY BODY VARIANT OF ALZHEIMER'S DISEASE
 primary_id: MESH:D020961
 alt_id: OMIM:127750;   RDO:0004559
 xref: GARD:3243;   ICD10CM:G31.83;   ICD9CM:331.82;   NCI:C84826
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants       view all columns           Sort by:
 
Lewy body dementia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ager advanced glycosylation end product-specific receptor JBrowse link 20 4,363,152 4,366,079 RGD:11554173
G Aif1 allograft inflammatory factor 1 JBrowse link 20 5,161,350 5,167,176 RGD:11554173
G Anxa5 annexin A5 JBrowse link 2 123,162,477 123,194,730 RGD:10053729
G Apoe apolipoprotein E JBrowse link 1 80,612,894 80,616,820 RGD:7771591
G Becn1 beclin 1 JBrowse link 10 89,209,944 89,225,297 RGD:11554173
G Ccr1 C-C motif chemokine receptor 1 JBrowse link 8 132,996,646 133,002,201 RGD:5688166
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit JBrowse link 3 176,533,182 176,547,965 RGD:1358509
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit JBrowse link 1 123,897,341 124,039,263 RGD:1358509
G Edn1 endothelin 1 JBrowse link 17 22,136,814 22,143,745 RGD:11554173
G Elk1 ETS transcription factor ELK1 JBrowse link X 1,287,875 1,304,822 RGD:7488914
G Eno2 enolase 2 JBrowse link 4 157,285,192 157,294,090 RGD:11554173
G Gba glucosylceramidase beta JBrowse link 2 188,511,781 188,522,602 RGD:5508424
RGD:8554872
RGD:12791014
RGD:11554173
RGD:7240710
G Gfap glial fibrillary acidic protein JBrowse link 10 90,990,762 90,999,435 RGD:11554173
G Gpr37 G protein-coupled receptor 37 JBrowse link 4 51,822,163 51,844,228 RGD:13504666
G Igf1r insulin-like growth factor 1 receptor JBrowse link 1 128,924,921 129,213,816 RGD:5129515
RGD:11554173
G Igf2 insulin-like growth factor 2 JBrowse link 1 215,828,102 215,839,081 RGD:5129515
RGD:11554173
G Igf2r insulin-like growth factor 2 receptor JBrowse link 1 48,176,095 48,264,482 RGD:11554173
G Ins2 insulin 2 JBrowse link 1 215,856,967 215,858,034 RGD:11554173
G Insr insulin receptor JBrowse link 12 1,682,527 1,816,414 RGD:11554173
G Klk6 kallikrein related-peptidase 6 JBrowse link 1 99,762,195 99,769,486 RGD:1358597
G Mag myelin-associated glycoprotein JBrowse link 1 89,345,325 89,360,905 RGD:11554173
G Map2 microtubule-associated protein 2 JBrowse link 9 73,204,753 73,462,965 RGD:6483091
RGD:11554173
G Ngf nerve growth factor JBrowse link 2 204,886,158 204,939,523 RGD:11554173
G Ngfr nerve growth factor receptor JBrowse link 10 83,389,828 83,408,061 RGD:10413896
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:1358529
G Ntrk1 neurotrophic receptor tyrosine kinase 1 JBrowse link 2 187,143,568 187,160,373 RGD:11554173
G Ntrk2 neurotrophic receptor tyrosine kinase 2 JBrowse link 17 5,934,651 6,245,778 RGD:11554173
G Pcna proliferating cell nuclear antigen JBrowse link 3 124,880,698 124,884,570 RGD:10448971
G Ppargc1a PPARG coactivator 1 alpha JBrowse link 14 63,095,291 63,190,688 RGD:11554173
G Prkn parkin RBR E3 ubiquitin protein ligase JBrowse link 1 48,880,015 50,069,998 RGD:10412737
G Septin4 septin 4 JBrowse link 10 74,860,068 74,884,196 RGD:13504670
G Snca synuclein alpha JBrowse link 4 90,782,412 90,883,236 RGD:6478704
RGD:8554872
RGD:13506723
RGD:11554173
RGD:7240710
RGD:6480103
RGD:6480095
RGD:6478792
G Sncb synuclein, beta JBrowse link 17 10,384,472 10,392,776 RGD:6219004
RGD:8554872
RGD:7240710
RGD:6480095
RGD:6478800
G Sncg synuclein, gamma JBrowse link 16 10,722,110 10,726,648 RGD:6478704
RGD:6480095
RGD:6478792
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:11554173
G Tardbp TAR DNA binding protein JBrowse link 5 165,432,089 165,442,232 RGD:5687180
G Th tyrosine hydroxylase JBrowse link 1 216,073,034 216,080,287 RGD:11554173
Parkinson's disease 4 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Snca synuclein alpha JBrowse link 4 90,782,412 90,883,236 RGD:7240710

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15553
    Diseases of the Aged 1172
      dementia 619
        Lewy body dementia 37
          Autosomal Dominant Diffuse Lewy Body Disease 0
          Diffuse Lewy Body Disease with Gaze Palsy 0
          Parkinson's disease 4 1
Path 2
Term Annotations click to browse term
  disease 15553
    disease of anatomical entity 14837
      nervous system disease 10167
        central nervous system disease 8267
          brain disease 7613
            disease of mental health 5552
              cognitive disorder 1846
                dementia 619
                  Lewy body dementia 37
                    Autosomal Dominant Diffuse Lewy Body Disease 0
                    Diffuse Lewy Body Disease with Gaze Palsy 0
                    Parkinson's disease 4 1
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.