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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:dengue hemorrhagic fever
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Accession:DOID:12206 term browser browse the term
Definition:A dengue disease that occurs when a person experiences a second infection with a heterologous Dengue virus serotype, which is transmitted_by Aedes mosquito bite. The infection has_symptom hemorrhagic lesions of the skin, has_symptom thrombocytopenia, has_symptom reduction in the fluid part of the blood, and has_symptom high fever. (DO)
Synonyms:exact_synonym: DHF;   Hemorrhagic Dengues;   Philippine Hemorrhagic Fever;   Severe Dengue;   Severe Dengues;   Singapore hemorrhagic fever;   Thai hemorrhagic fever;   dengue haemorrhagic fever;   hemorrhagic dengue
 primary_id: MESH:D019595
 xref: ICD10CM:A91;   NCI:C34683
For additional species annotation, visit the Alliance of Genome Resources.



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dengue hemorrhagic fever term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD1D CD1d molecule disease_progression ISO protein:increased expression:cd14-positive monocyte (human) RGD PMID:24945350 RGD:127345113 NCBI chr38:23,489,169...23,491,712 JBrowse link
G CD209 CD209 molecule susceptibility
severity
ISO DNA:SNP:promoter: -336 A>G (rs4804803) (human)
DNA:SNPs:introns, promoter:multiple (human)
RGD PMID:15838506 PMID:21245921 RGD:39938993 RGD:41410809 NCBI chr20:52,517,759...52,542,085
Ensembl chr20:52,518,036...52,520,942
JBrowse link
G CLEC5A C-type lectin domain containing 5A ISO CTD Direct Evidence: therapeutic CTD PMID:18496526 NCBI chr16:7,242,424...7,269,986
Ensembl chr16:7,243,018...7,269,418
JBrowse link
G IL21 interleukin 21 severity ISO protein:increased expression:blood serum (human) RGD PMID:24858204 RGD:127285368 NCBI chr19:17,641,833...17,651,275
Ensembl chr19:17,641,833...17,651,266
JBrowse link
G IL29L interleukin 29-like ameliorates ISO DNA:SNP:enhancer:-1043C>T (rs7247086) (human) RGD PMID:31981768 RGD:126848742 NCBI chr24:36,440,445...36,441,017
Ensembl chr24:36,440,445...36,441,017
JBrowse link
G OSBP oxysterol binding protein ISO mRNA:increased expression:peripheral blood mononuclear cell RGD PMID:28241052 RGD:41404654 NCBI chr18:37,159,511...37,191,720
Ensembl chr18:37,159,576...37,189,731
JBrowse link
G PLCE1 phospholipase C epsilon 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22001756 NCBI chr28:8,209,707...8,484,427
Ensembl chr28:8,210,058...8,481,770
JBrowse link
G SLC6A4 solute carrier family 6 member 4 severity ISO DNA;polymorphism:5'utr: (rs25531) (human) RGD PMID:30452889 RGD:38676265 NCBI chr 9:44,224,026...44,259,655
Ensembl chr 9:44,224,229...44,259,736
JBrowse link
G TAP2 transporter 2, ATP binding cassette subfamily B member susceptibility ISO DNA:SNPs: : RGD PMID:18071882 RGD:6482261 NCBI chr12:2,407,512...2,417,469
Ensembl chr12:2,378,126...2,432,303
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 13842
    disease by infectious agent 1808
      viral infectious disease 1505
        Arbovirus Infections 52
          dengue disease 18
            dengue hemorrhagic fever 9
              dengue shock syndrome 0
Path 2
Term Annotations click to browse term
  disease 13842
    disease by infectious agent 1808
      viral infectious disease 1505
        RNA Virus Infections 1307
          Flaviviridae Infections 146
            Flavivirus Infections 42
              dengue disease 18
                dengue hemorrhagic fever 9
                  dengue shock syndrome 0
paths to the root