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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:allergic disease
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Accession:DOID:1205 term browser browse the term
Definition:An immune system disease that is an exaggerated immune response to allergens, such as insect venom, dust mites, pollen, pet dander, drugs or some foods. (DO)
Synonyms:exact_synonym: allergic hypersensitivity disease;   allergic reaction;   allergic reactions;   allergies;   allergy;   hypersensitivities;   hypersensitivity;   hypersensitivity reaction type I disease
 primary_id: MESH:D006967
 xref: ICD10CM:T78.40;   NCI:C3114
For additional species annotation, visit the Alliance of Genome Resources.



show annotations for term's descendants           Sort by:
 
allergic disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcf1 ATP-binding cassette, sub-family F (GCN20), member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr17:36,267,711...36,280,642
Ensembl chr17:36,267,711...36,280,653
JBrowse link
G Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 susceptibility ISO DNA:deletion:intron:IVS16+1464-1751del (human) RGD PMID:10200023 RGD:8142344 NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790
JBrowse link
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) susceptibility ISO DNA:polymorphism: :p.M235T (human) RGD PMID:10200023 RGD:8142344 NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445
JBrowse link
G Akr1b3 aldo-keto reductase family 1, member B3 (aldose reductase) ISO associated with Diabetes Mellitus, Experimental RGD PMID:16979157 RGD:1626088 NCBI chr 6:34,280,865...34,294,424
Ensembl chr 6:34,279,369...34,294,413
JBrowse link
G Alb albumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:8431628 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461
JBrowse link
G Bcl2a1b B cell leukemia/lymphoma 2 related protein A1b IMP RGD PMID:11733571 RGD:734640 NCBI chr 9:89,081,326...89,089,891
Ensembl chr 9:89,081,262...89,089,880
JBrowse link
G Casp1 caspase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290
JBrowse link
G Ccl11 chemokine (C-C motif) ligand 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr11:81,948,658...81,953,781
Ensembl chr11:81,948,649...81,953,781
JBrowse link
G Ccl12 chemokine (C-C motif) ligand 12 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr11:81,992,671...81,994,225
Ensembl chr11:81,992,671...81,994,226
JBrowse link
G Ccl17 chemokine (C-C motif) ligand 17 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 8:95,535,996...95,538,666
Ensembl chr 8:95,537,081...95,538,664
JBrowse link
G Ccl19 chemokine (C-C motif) ligand 19 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 4:42,754,525...42,756,365
Ensembl chr 4:42,754,525...42,756,577
JBrowse link
G Ccl2 chemokine (C-C motif) ligand 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15585374 PMID:21625544 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Ccl20 chemokine (C-C motif) ligand 20 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 1:83,094,487...83,096,888
Ensembl chr 1:83,094,487...83,096,888
JBrowse link
G Ccl24 chemokine (C-C motif) ligand 24 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 5:135,598,789...135,601,977
Ensembl chr 5:135,598,791...135,601,903
JBrowse link
G Ccl3 chemokine (C-C motif) ligand 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15585374 PMID:23624239 NCBI chr11:83,538,669...83,540,204
Ensembl chr11:83,538,670...83,540,181
JBrowse link
G Ccl4 chemokine (C-C motif) ligand 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15585374 PMID:21625544 NCBI chr11:83,553,410...83,555,509
Ensembl chr11:83,553,410...83,555,509
JBrowse link
G Ccl7 chemokine (C-C motif) ligand 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr11:81,936,538...81,938,351
Ensembl chr11:81,936,538...81,938,351
JBrowse link
G Ccl9 chemokine (C-C motif) ligand 9 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr11:83,463,743...83,469,462
Ensembl chr11:83,463,745...83,469,462
JBrowse link
G Ccr1 chemokine (C-C motif) receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 9:123,762,163...123,768,729
Ensembl chr 9:123,762,161...123,768,729
JBrowse link
G Ccr2 chemokine (C-C motif) receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 9:123,901,954...123,913,594
Ensembl chr 9:123,901,987...123,913,594
JBrowse link
G Ccr6 chemokine (C-C motif) receptor 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr17:8,454,875...8,477,353
Ensembl chr17:8,454,875...8,475,973
JBrowse link
G Ccr9 chemokine (C-C motif) receptor 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 9:123,596,276...123,612,522
Ensembl chr 9:123,507,504...123,613,395
JBrowse link
G Cd14 CD14 antigen resistance ISO DNA:polymorphism:promoter:c. -159C>T (human) RGD PMID:19222419 RGD:4144798 NCBI chr18:36,858,117...36,859,868
Ensembl chr18:36,858,120...36,859,851
JBrowse link
G Cd274 CD274 antigen ISO CTD Direct Evidence: marker/mechanism CTD PMID:20488241 PMID:23624239 NCBI chr19:29,339,428...29,365,495
Ensembl chr19:29,344,855...29,365,495
JBrowse link
G Cd40lg CD40 ligand ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr  X:56,257,503...56,269,402
Ensembl chr  X:56,257,503...56,269,402
JBrowse link
G Clec4a3 C-type lectin domain family 4, member a3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23624239 NCBI chr 6:122,929,474...122,946,837
Ensembl chr 6:122,929,474...122,946,834
JBrowse link
G Commd1 COMM domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22216203 NCBI chr11:22,849,728...22,934,539
Ensembl chr11:22,846,136...22,932,382
JBrowse link
G Cx3cl1 chemokine (C-X3-C motif) ligand 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 8:95,498,808...95,509,055
Ensembl chr 8:95,498,637...95,509,055
JBrowse link
G Cxcl1 chemokine (C-X-C motif) ligand 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 5:91,039,104...91,040,980
Ensembl chr 5:91,039,100...91,040,974
JBrowse link
G Cxcl15 chemokine (C-X-C motif) ligand 15 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
JBrowse link
G Cxcl3 chemokine (C-X-C motif) ligand 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 5:90,933,960...90,935,952
Ensembl chr 5:90,933,962...90,937,459
JBrowse link
G Cxcl9 chemokine (C-X-C motif) ligand 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 5:92,469,190...92,475,938
Ensembl chr 5:92,469,206...92,475,938
JBrowse link
G Cxcr2 chemokine (C-X-C motif) receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 1:74,193,153...74,200,405
Ensembl chr 1:74,193,148...74,200,405
JBrowse link
G Cxcr3 chemokine (C-X-C motif) receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr  X:100,775,141...100,777,753
Ensembl chr  X:100,775,141...100,777,875
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19022366 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 severity ISO DNA:SNP: :927T>C (human) RGD PMID:16776674 RGD:4782072 NCBI chr  X:105,617,952...105,647,329
Ensembl chr  X:105,617,952...105,647,285
JBrowse link
G Dsg1a desmoglein 1 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:23974871 NCBI chr18:20,443,930...20,476,410
Ensembl chr18:20,443,868...20,476,407
JBrowse link
G Fcgr4 Fc receptor, IgG, low affinity IV treatment ISO associated with Purpura, Thrombocytopenic, Idiopathic RGD PMID:22025730 RGD:11352264 NCBI chr 1:170,846,495...170,857,330
Ensembl chr 1:170,846,489...170,857,330
JBrowse link
G Foxp3 forkhead box P3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27965764 NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484
JBrowse link
G Gstm1 glutathione S-transferase, mu 1 susceptibility ISO DNA:deletion: : RGD PMID:16580705 RGD:5490996 NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289
JBrowse link
G Gstp1 glutathione S-transferase, pi 1 susceptibility ISO DNA:polymorphism:exon:p.I105V (rs1695) (human) RGD PMID:20526719 RGD:5133266 NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985
JBrowse link
G H2-Aa histocompatibility 2, class II antigen A, alpha susceptibility ISO DNA:polymorphism (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphisms (human)
CTD
RGD
PMID:8725357 PMID:15853900 PMID:10202362 PMID:16112029 RGD:5147651, RGD:5147866, RGD:5147826 NCBI chr17:34,501,718...34,506,797
Ensembl chr17:34,501,718...34,506,797
JBrowse link
G H2-Ab1 histocompatibility 2, class II antigen A, beta 1 susceptibility ISO DNA:polymorphism (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphisms (human)
CTD
RGD
PMID:8725357 PMID:20684489 PMID:10202362 PMID:16112029 PMID:10689122 More... RGD:5147606, RGD:5147866, RGD:5147826, RGD:5147814, RGD:5147651 NCBI chr17:34,482,201...34,488,392
Ensembl chr17:34,476,663...34,488,393
JBrowse link
G H2-Ea histocompatibility 2, class II antigen E alpha ISO RGD PMID:9104792 RGD:5490205 NCBI chr17:34,560,926...34,563,619
Ensembl chr17:34,560,933...34,563,619
JBrowse link
G H2-Eb1 histocompatibility 2, class II antigen E beta susceptibility ISO DNA:polymorphism (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphisms (human)
CTD
RGD
PMID:8725357 PMID:15853900 PMID:16112029 PMID:10689122 RGD:5147651, RGD:5147826, RGD:5147814 NCBI chr17:34,524,841...34,535,648
Ensembl chr17:34,524,841...34,535,648
JBrowse link
G H2-M2 histocompatibility 2, M region locus 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23541086 NCBI chr17:37,791,742...37,794,445
Ensembl chr17:37,791,742...37,794,443
JBrowse link
G Hp haptoglobin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16597321 NCBI chr 8:110,301,760...110,305,804
Ensembl chr 8:110,301,760...110,305,804
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO associated with Giardiasis;protein:increased expression:serum RGD PMID:7524984 PMID:15587302 RGD:8158114, RGD:8547689 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
JBrowse link
G Ifng interferon gamma ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:10886234 PMID:21625544 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Il13 interleukin 13 ISO DNA:SNP:promoter, 3' utr:-1055C>T, 4738G>A (human)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:21625544 PMID:11588017 RGD:4765128 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529
JBrowse link
G Il16 interleukin 16 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23624239 NCBI chr 7:83,292,027...83,395,479
Ensembl chr 7:83,292,033...83,394,934
JBrowse link
G Il17a interleukin 17A ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 1:20,801,129...20,804,720
Ensembl chr 1:20,801,129...20,804,720
JBrowse link
G Il18 interleukin 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140
JBrowse link
G Il1b interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il1r1 interleukin 1 receptor, type I ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 1:40,261,651...40,355,361
Ensembl chr 1:40,264,240...40,356,417
JBrowse link
G Il1r2 interleukin 1 receptor, type II ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 1:40,123,872...40,164,390
Ensembl chr 1:40,113,239...40,164,391
JBrowse link
G Il2 interleukin 2 IMP RGD PMID:21509781 RGD:5147912 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
JBrowse link
G Il2rb interleukin 2 receptor, beta chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr15:78,363,456...78,396,569
Ensembl chr15:78,363,456...78,379,471
JBrowse link
G Il4 interleukin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16095146 PMID:21625544 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
JBrowse link
G Il5ra interleukin 5 receptor, alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 6:106,687,336...106,725,998
Ensembl chr 6:106,687,318...106,725,998
JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Il6st interleukin 6 signal transducer ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr13:112,600,604...112,643,394
Ensembl chr13:112,600,604...112,646,620
JBrowse link
G Itgb2 integrin beta 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr10:77,366,164...77,401,542
Ensembl chr10:77,366,086...77,401,542
JBrowse link
G Kng2 kininogen 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11160071 NCBI chr16:22,804,602...22,847,851
Ensembl chr16:22,804,604...22,848,232
JBrowse link
G Lta lymphotoxin A ISO DNA:polymorphism, haplotype
associated with Nasal Polyps
RGD PMID:11591192 PMID:22545387 RGD:8548785, RGD:8548802 NCBI chr17:35,422,141...35,424,568
Ensembl chr17:35,422,141...35,424,327
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 ISO CTD Direct Evidence: therapeutic CTD PMID:21544193 NCBI chr11:110,289,928...110,416,348
Ensembl chr11:110,289,948...110,416,348
JBrowse link
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) ISO DNA:polymorphisms:promoter: RGD PMID:14962818 RGD:4891046 NCBI chr10:75,695,187...75,696,111
Ensembl chr10:75,695,187...75,696,074
JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16766537 NCBI chr 4:148,123,534...148,144,019
Ensembl chr 4:148,123,534...148,144,008
JBrowse link
G Mylk myosin, light polypeptide kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:15621374 NCBI chr16:34,565,569...34,822,806
Ensembl chr16:34,565,580...34,822,790
JBrowse link
G Pf4 platelet factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 5:90,920,294...90,921,242
Ensembl chr 5:90,920,294...90,921,242
JBrowse link
G Ppbp pro-platelet basic protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:23624239 NCBI chr 5:90,916,377...90,917,922
Ensembl chr 5:90,916,377...90,917,922
JBrowse link
G Selp selectin, platelet ISO CTD Direct Evidence: marker/mechanism CTD PMID:12929084 NCBI chr 1:163,942,833...163,977,595
Ensembl chr 1:163,942,833...163,977,595
JBrowse link
G Spp1 secreted phosphoprotein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916
JBrowse link
G Tac1 tachykinin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11160071 NCBI chr 6:7,555,061...7,562,978
Ensembl chr 6:7,554,879...7,565,834
JBrowse link
G Tap1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) ISO DNA:polymorphism, haplotype: :p.V333I (human) RGD PMID:11591192 RGD:8548785 NCBI chr17:34,406,530...34,416,199
Ensembl chr17:34,406,527...34,416,199
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19138248 PMID:21625544 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16095146 PMID:21625544 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447
JBrowse link
G Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 4:144,938,938...144,973,453
Ensembl chr 4:144,940,033...144,973,440
JBrowse link
abacavir allergy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G H2-M2 histocompatibility 2, M region locus 2 ISO ClinVar Annotator: match by term: Abacavir hypersensitivity ClinVar
OMIM
PMID:11888582 PMID:11943262 PMID:12462283 PMID:15024131 PMID:15247624 More... NCBI chr17:37,791,742...37,794,445
Ensembl chr17:37,791,742...37,794,443
JBrowse link
acquired angioedema term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F12 coagulation factor XII (Hageman factor) disease_progression ISO RGD PMID:9129025 RGD:11565081 NCBI chr13:55,565,771...55,574,617
Ensembl chr13:55,565,771...55,574,606
JBrowse link
G F2 coagulation factor II disease_progression ISO protein:increased expression:plasma: RGD PMID:9129025 RGD:11565081 NCBI chr 2:91,442,742...91,466,802
Ensembl chr 2:91,455,665...91,466,759
JBrowse link
G F7 coagulation factor VII disease_progression ISO RGD PMID:9129025 RGD:11565081 NCBI chr 8:13,075,499...13,085,809
Ensembl chr 8:13,076,034...13,085,809
JBrowse link
G G6pdx glucose-6-phosphate dehydrogenase X-linked ISO ClinVar Annotator: match by term: Susceptibility to angioedema induced by ACE inhibitors ClinVar PMID:1551674 PMID:1972698 PMID:1978554 PMID:1978555 PMID:2503817 More... NCBI chr  X:73,453,089...73,472,486
Ensembl chr  X:73,453,089...73,472,800
JBrowse link
G Kng2 kininogen 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9734886 NCBI chr16:22,804,602...22,847,851
Ensembl chr16:22,804,604...22,848,232
JBrowse link
G Serping1 serine (or cysteine) peptidase inhibitor, clade G, member 1 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:9734886 PMID:23406939 NCBI chr 2:84,595,704...84,605,778
Ensembl chr 2:84,595,731...84,605,788
JBrowse link
G Xpnpep2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound susceptibility ISO ClinVar Annotator: match by term: Susceptibility to angioedema induced by ACE inhibitors
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
PMID:16175507 PMID:20625347 PMID:21898657 NCBI chr  X:47,195,790...47,225,859
Ensembl chr  X:47,197,602...47,225,858
JBrowse link
acute asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cxcl15 chemokine (C-X-C motif) ligand 15 treatment ISO RGD PMID:30059697 RGD:39939057 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
JBrowse link
allergic asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl26 chemokine (C-C motif) ligand 26 treatment IDA RGD PMID:25530546 RGD:11081163 NCBI chr 5:135,589,302...135,592,423
Ensembl chr 5:135,589,302...135,592,423
JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 treatment IMP RGD PMID:23933317 RGD:40903070 NCBI chr  X:105,617,952...105,647,329
Ensembl chr  X:105,617,952...105,647,285
JBrowse link
G Epx eosinophil peroxidase ISO protein:increased expression:urine: RGD PMID:11846868 RGD:13506893 NCBI chr11:87,754,824...87,766,362
Ensembl chr11:87,754,826...87,766,362
JBrowse link
G H2-Eb1 histocompatibility 2, class II antigen E beta susceptibility ISO RGD PMID:22397267 RGD:13506905 NCBI chr17:34,524,841...34,535,648
Ensembl chr17:34,524,841...34,535,648
JBrowse link
G H2-M2 histocompatibility 2, M region locus 2 susceptibility ISO DNA:polymorphism: RGD PMID:28380482 RGD:13506910 NCBI chr17:37,791,742...37,794,445
Ensembl chr17:37,791,742...37,794,443
JBrowse link
G H2-Pa histocompatibility 2, P region alpha locus susceptibility ISO DNA:polymorphism: RGD PMID:28380482 RGD:13506910 NCBI chr17:34,303,587...34,304,826
Ensembl chr17:34,303,575...34,304,797
JBrowse link
G Il25 interleukin 25 treatment IMP RGD PMID:17889290 RGD:40902975 NCBI chr14:55,170,152...55,173,294
Ensembl chr14:55,170,152...55,173,294
JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 exacerbates IEP
IDA
RGD PMID:21592044 PMID:21592044 RGD:126928124, RGD:126928124 NCBI chr17:48,539,763...48,553,955
Ensembl chr17:48,539,796...48,553,952
JBrowse link
allergic bronchopulmonary aspergillosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl17 chemokine (C-C motif) ligand 17 ISO associated with Cystic Fibrosis RGD PMID:17898016 RGD:4145612 NCBI chr 8:95,535,996...95,538,666
Ensembl chr 8:95,537,081...95,538,664
JBrowse link
G Ccr1 chemokine (C-C motif) receptor 1 IMP RGD PMID:15951834 RGD:5688155 NCBI chr 9:123,762,163...123,768,729
Ensembl chr 9:123,762,161...123,768,729
JBrowse link
G Ccr2 chemokine (C-C motif) receptor 2 IMP RGD PMID:10946288 RGD:8661731 NCBI chr 9:123,901,954...123,913,594
Ensembl chr 9:123,901,987...123,913,594
JBrowse link
G Cftr cystic fibrosis transmembrane conductance regulator ISO DNA:mutations: : RGD PMID:11243954 RGD:4140482 NCBI chr 6:18,170,686...18,322,769
Ensembl chr 6:18,170,686...18,322,767
JBrowse link
G H2-Ab1 histocompatibility 2, class II antigen A, beta 1 susceptibility ISO associated with cystic fibrosis; DNA:polymorphisms: :DQB1*06:02, DQB1*02:01(human) RGD PMID:23278646 RGD:36049760 NCBI chr17:34,482,201...34,488,392
Ensembl chr17:34,476,663...34,488,393
JBrowse link
G H2-Eb1 histocompatibility 2, class II antigen E beta susceptibility ISO associated with cystic fibrosis; DNA:polymorphisms: : RGD PMID:23278646 RGD:36049760 NCBI chr17:34,524,841...34,535,648
Ensembl chr17:34,524,841...34,535,648
JBrowse link
G Icam1 intercellular adhesion molecule 1 IEP RGD PMID:7743671 RGD:8547590 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
JBrowse link
G Il1a interleukin 1 alpha IEP RGD PMID:8699818 RGD:7794730 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
JBrowse link
G Mbl2 mannose-binding lectin (protein C) 2 susceptibility ISO Chronic Necrotizing Pulmonary Aspergillosis; DNA:missense mutation:exon:p.R52C (human)
DNA:SNP:intron:1011G>A(human)
RGD PMID:11474427 PMID:16487239 RGD:4889577, RGD:8693711 NCBI chr19:30,210,306...30,217,087
Ensembl chr19:30,210,342...30,217,087
JBrowse link
G Tlr9 toll-like receptor 9 susceptibility ISO
IMP
DNA:SNP:promoter:g.-1237T>C rs5743836 (human) RGD PMID:18275280 PMID:18936185 RGD:5130863, RGD:5130858 NCBI chr 9:106,099,797...106,104,075
Ensembl chr 9:106,099,797...106,104,082
JBrowse link
G Tnf tumor necrosis factor IEP RGD PMID:8699818 RGD:7794730 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a susceptibility ISO DNA:snps:5' utr, exon:g.-609G>T rs4149570, g.36A>G rs767455 (human) RGD PMID:20646338 RGD:5131174 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447
JBrowse link
allergic conjunctivitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl11 chemokine (C-C motif) ligand 11 ISO mRNA:increased expression:conjunctiva RGD PMID:12682842 RGD:2307196 NCBI chr11:81,948,658...81,953,781
Ensembl chr11:81,948,649...81,953,781
JBrowse link
G Ccl2 chemokine (C-C motif) ligand 2 IMP RGD PMID:19553621 RGD:8548840 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Ccl5 chemokine (C-C motif) ligand 5 ISO mRNA:increased expression:conjunctiva RGD PMID:12682842 RGD:2307196 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344
JBrowse link
G Ccl7 chemokine (C-C motif) ligand 7 ISO protein:increased expression:conjunctiva RGD PMID:11090473 RGD:6483824 NCBI chr11:81,936,538...81,938,351
Ensembl chr11:81,936,538...81,938,351
JBrowse link
G Ccr3 chemokine (C-C motif) receptor 3 IMP RGD PMID:18658092 RGD:6893389 NCBI chr 9:123,817,799...123,831,729
Ensembl chr 9:123,822,009...123,831,726
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO RGD PMID:8766745 RGD:8547686 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
JBrowse link
G Ifng interferon gamma ISO
IMP
RGD PMID:12234900 PMID:16123425 RGD:8142386, RGD:8142391 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Il10 interleukin 10 treatment ISO
IMP
protein:increased expression:tear RGD PMID:22092652 PMID:16914468 PMID:15144463 PMID:19060266 RGD:7364837, RGD:11041889, RGD:7365076, RGD:7365027 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Il13 interleukin 13 ISO associated with Allergic Rhinitis;DNA:SNPs, haplotype:promoter, exon:-1112C>T (rs1800925), p.R130Q (rs20541) (human) RGD PMID:9191598 PMID:22023794 RGD:8549533, RGD:8549595 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529
JBrowse link
G Il1b interleukin 1 beta treatment IEP RGD PMID:9326725 RGD:7401198 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il1rn interleukin 1 receptor antagonist treatment ISO human protein in a mouse model RGD PMID:10549671 RGD:8549802 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506
JBrowse link
G Il4ra interleukin 4 receptor, alpha susceptibility ISO associated with rhinitis; DNA:SNP: : rs2107356 (human) RGD PMID:20002627 RGD:4890389 NCBI chr 7:125,151,443...125,178,646
Ensembl chr 7:125,151,292...125,178,646
JBrowse link
G Irf1 interferon regulatory factor 1 ISO RGD PMID:14605445 RGD:5128787 NCBI chr11:53,660,841...53,669,200
Ensembl chr11:53,660,841...53,669,200
JBrowse link
G Lck lymphocyte protein tyrosine kinase ISO protein:increased phosphorylation:T cell RGD PMID:14507881 RGD:1600225 NCBI chr 4:129,442,137...129,467,434
Ensembl chr 4:129,442,137...129,467,434
JBrowse link
G Muc1 mucin 1, transmembrane severity ISO RGD PMID:17177679 RGD:7349351 NCBI chr 3:89,136,363...89,140,688
Ensembl chr 3:89,136,364...89,140,688
JBrowse link
G Muc2 mucin 2 severity ISO RGD PMID:17177679 RGD:7349351 NCBI chr 7:141,276,583...141,308,428
Ensembl chr 7:141,276,583...141,308,430
JBrowse link
G Muc4 mucin 4 severity ISO
IEP
RGD PMID:17177679 PMID:11581187 RGD:7349351, RGD:7349400 NCBI chr16:32,555,089...32,602,761
Ensembl chr16:32,555,015...32,602,754
JBrowse link
G Pla2g2a phospholipase A2, group IIA (platelets, synovial fluid) ISO protein:increased expression:body fluid or substance RGD PMID:21042565 RGD:6482725 NCBI chr 4:138,559,168...138,562,500
Ensembl chr 4:138,559,171...138,562,497
JBrowse link
G Tgfb1 transforming growth factor, beta 1 treatment IMP RGD PMID:16914468 RGD:11041889 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Tlr2 toll-like receptor 2 IMP associated with Staphylococcal Infections; RGD PMID:19358332 RGD:8552826 NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074
JBrowse link
G Tlr4 toll-like receptor 4 IMP
ISO
mRNA,protein:increased expression:conjunctiva: RGD PMID:21820713 PMID:16023216 PMID:21391988 RGD:7777131, RGD:7794849, RGD:7794770 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521
JBrowse link
G Tlr9 toll-like receptor 9 ISO mRNA,protein:decreased expression:conjunctiva: RGD PMID:16023216 RGD:7794849 NCBI chr 9:106,099,797...106,104,075
Ensembl chr 9:106,099,797...106,104,082
JBrowse link
G Tnc tenascin C ISO DNA:SNPs: :multiple (human) RGD PMID:18305139 RGD:4889589 NCBI chr 4:63,878,022...63,965,554
Ensembl chr 4:63,878,022...63,965,252
JBrowse link
allergic contact dermatitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca6 ATP-binding cassette, sub-family A (ABC1), member 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr11:110,065,464...110,142,811
Ensembl chr11:110,067,646...110,142,602
JBrowse link
G Asrgl1 asparaginase like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr19:9,089,083...9,112,930
Ensembl chr19:9,087,232...9,113,000
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bmp6 bone morphogenetic protein 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr13:38,529,692...38,684,290
Ensembl chr13:38,529,083...38,684,278
JBrowse link
G Calcrl calcitonin receptor-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr 2:84,160,970...84,255,786
Ensembl chr 2:84,160,970...84,255,755
JBrowse link
G Casp8 caspase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr 1:58,834,398...58,886,662
Ensembl chr 1:58,834,533...58,886,662
JBrowse link
G Ccl17 chemokine (C-C motif) ligand 17 IEP RGD PMID:15491423 RGD:1626251 NCBI chr 8:95,535,996...95,538,666
Ensembl chr 8:95,537,081...95,538,664
JBrowse link
G Ccl19 chemokine (C-C motif) ligand 19 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17597826 NCBI chr 4:42,754,525...42,756,365
Ensembl chr 4:42,754,525...42,756,577
JBrowse link
G Ccl5 chemokine (C-C motif) ligand 5 IEP protein:increased expression:ear (mouse) RGD PMID:15491423 RGD:1626251 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344
JBrowse link
G Ccr1 chemokine (C-C motif) receptor 1 ISO RGD PMID:18844696 RGD:5688176 NCBI chr 9:123,762,163...123,768,729
Ensembl chr 9:123,762,161...123,768,729
JBrowse link
G Ccr2 chemokine (C-C motif) receptor 2 IMP
ISO
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:17374397 PMID:10899907 RGD:8661227 NCBI chr 9:123,901,954...123,913,594
Ensembl chr 9:123,901,987...123,913,594
JBrowse link
G Ccr3 chemokine (C-C motif) receptor 3 IDA RGD PMID:22075493 RGD:6892916 NCBI chr 9:123,817,799...123,831,729
Ensembl chr 9:123,822,009...123,831,726
JBrowse link
G Ccr5 chemokine (C-C motif) receptor 5 ISO mRNA:increased expression:skin, lymph node (rat) RGD PMID:16977379 RGD:2325935 NCBI chr 9:123,921,557...123,934,153
Ensembl chr 9:123,921,580...123,947,736
JBrowse link
G Cd36 CD36 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr 5:17,986,688...18,093,957
Ensembl chr 5:17,986,688...18,093,799
JBrowse link
G Cd3d CD3 antigen, delta polypeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:17597826 NCBI chr 9:44,893,067...44,898,350
Ensembl chr 9:44,893,084...44,898,637
JBrowse link
G Cidec cell death-inducing DFFA-like effector c ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr 6:113,401,595...113,412,721
Ensembl chr 6:113,401,595...113,412,721
JBrowse link
G Cish cytokine inducible SH2-containing protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr 9:107,173,858...107,179,983
Ensembl chr 9:107,173,225...107,179,983
JBrowse link
G Cntn3 contactin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17597826 NCBI chr 6:102,140,265...102,541,575
Ensembl chr 6:102,139,616...102,550,062
JBrowse link
G Crem cAMP responsive element modulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr18:3,263,181...3,337,688
Ensembl chr18:3,266,048...3,337,748
JBrowse link
G Ctsc cathepsin C ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr 7:87,927,220...87,965,069
Ensembl chr 7:87,927,293...87,960,096
JBrowse link
G Cxcl2 chemokine (C-X-C motif) ligand 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23178550 NCBI chr 5:91,051,758...91,053,797
Ensembl chr 5:91,051,730...91,053,797
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11312644 PMID:19022366 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Emb embigin ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr13:117,357,109...117,410,951
Ensembl chr13:117,345,072...117,410,951
JBrowse link
G Ets2 E26 avian leukemia oncogene 2, 3' domain ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr16:95,503,274...95,522,093
Ensembl chr16:95,502,942...95,522,095
JBrowse link
G F13a1 coagulation factor XIII, A1 subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr13:37,051,150...37,234,220
Ensembl chr13:37,051,152...37,234,220
JBrowse link
G Fgl2 fibrinogen-like protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr 5:21,577,671...21,583,384
Ensembl chr 5:21,577,640...21,583,372
JBrowse link
G Flt1 FMS-like tyrosine kinase 1 ISO mRNA:protein:skin: RGD PMID:7876550 RGD:7421586 NCBI chr 5:147,498,414...147,663,419
Ensembl chr 5:147,498,414...147,662,821
JBrowse link
G Fyb FYN binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr15:6,552,280...6,695,089
Ensembl chr15:6,552,334...6,692,794
JBrowse link
G Grk2 G protein-coupled receptor kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr19:4,336,027...4,356,350
Ensembl chr19:4,336,029...4,356,250
JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr 1:192,903,948...192,946,353
Ensembl chr 1:192,903,942...192,946,383
JBrowse link
G Ifi30 interferon gamma inducible protein 30 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17597826 NCBI chr 8:71,215,418...71,219,307
Ensembl chr 8:71,215,419...71,219,307
JBrowse link
G Ifng interferon gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:11312644 PMID:12484431 PMID:15347381 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Igsf6 immunoglobulin superfamily, member 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr 7:120,663,290...120,673,753
Ensembl chr 7:120,663,290...120,673,795
JBrowse link
G Il10 interleukin 10 treatment IDA
ISO
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:15347381 PMID:23760007 RGD:7364806 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Il18 interleukin 18 treatment IEP
ISO
IMP
mRNA:increased expression:skin
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:27585668 PMID:9781803 PMID:12874202 RGD:8655902, RGD:8655940 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140
JBrowse link
G Il18bp interleukin 18 binding protein treatment ISO RGD PMID:12874202 RGD:8655940 NCBI chr 7:101,664,281...101,669,699
Ensembl chr 7:101,664,092...101,667,897
JBrowse link
G Il1a interleukin 1 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:23178550 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
JBrowse link
G Il2 interleukin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11312644 PMID:22245253 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
JBrowse link
G Il2ra interleukin 2 receptor, alpha chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr 2:11,647,603...11,698,005
Ensembl chr 2:11,647,618...11,698,004
JBrowse link
G Il4 interleukin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12484431 PMID:21804303 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
JBrowse link
G Il5 interleukin 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15347381 NCBI chr11:53,611,621...53,615,930
Ensembl chr11:53,611,621...53,615,933
JBrowse link
G Ipcef1 interaction protein for cytohesin exchange factors 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr10:6,835,779...6,973,185
Ensembl chr10:6,835,796...7,002,478
JBrowse link
G Itgam integrin alpha M ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr 7:127,661,812...127,717,663
Ensembl chr 7:127,661,812...127,717,663
JBrowse link
G Jam2 junction adhesion molecule 2 IMP RGD PMID:16297198 RGD:7488919 NCBI chr16:84,571,011...84,623,268
Ensembl chr16:84,571,011...84,622,816
JBrowse link
G Jam3 junction adhesion molecule 3 IMP RGD PMID:16297198 RGD:7488919 NCBI chr 9:27,008,680...27,066,739
Ensembl chr 9:27,008,680...27,066,717
JBrowse link
G Kdr kinase insert domain protein receptor ISO mRNA:protein:skin: RGD PMID:7876550 RGD:7421586 NCBI chr 5:76,093,487...76,139,885
Ensembl chr 5:76,093,487...76,139,118
JBrowse link
G Kmo kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr 1:175,459,759...175,488,419
Ensembl chr 1:175,447,947...175,489,682
JBrowse link
G Mc1r melanocortin 1 receptor IEP RGD PMID:20126537 RGD:5687319 NCBI chr 8:124,133,821...124,137,483
Ensembl chr 8:124,133,846...124,137,483
JBrowse link
G Meox1 mesenchyme homeobox 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr11:101,768,336...101,785,309
Ensembl chr11:101,768,336...101,785,200
JBrowse link
G Mir155 microRNA 155 treatment ISO RGD PMID:29404871 RGD:21079472 NCBI chr16:84,511,028...84,511,092
Ensembl chr16:84,511,028...84,511,092
JBrowse link
G Mir21a microRNA 21a treatment ISO RGD PMID:29282578 RGD:41404666 NCBI chr11:86,474,893...86,474,984
Ensembl chr11:86,474,893...86,474,984
JBrowse link
G Mki67 antigen identified by monoclonal antibody Ki 67 IDA RGD PMID:21294775 RGD:6483538 NCBI chr 7:135,291,513...135,318,286
Ensembl chr 7:135,291,513...135,318,090
JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO
IMP
mRNA:increased expression:skin, lymph node RGD PMID:16977379 PMID:10359808 RGD:2325935, RGD:8693317 NCBI chr 9:7,445,822...7,455,975
Ensembl chr 9:7,445,822...7,455,975
JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO
IMP
mRNA:increased expression:skin, lymph node RGD PMID:16977379 PMID:10359808 PMID:10415717 RGD:2325935, RGD:8693317, RGD:8547869 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
JBrowse link
G Mrc1 mannose receptor, C type 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr 2:14,234,225...14,336,834
Ensembl chr 2:14,234,203...14,336,868
JBrowse link
G Mxd1 MAX dimerization protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr 6:86,624,026...86,646,217
Ensembl chr 6:86,624,024...86,646,143
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr12:32,870,334...32,903,368
Ensembl chr12:32,869,544...32,903,348
JBrowse link
G Nat1 N-acetyl transferase 1 susceptibility ISO DNA:polymorphism: : RGD PMID:19663877 RGD:8552666 NCBI chr 8:67,943,620...67,945,183
Ensembl chr 8:67,933,573...67,944,756
JBrowse link
G Nat2 N-acetyltransferase 2 (arylamine N-acetyltransferase) susceptibility ISO DNA:polymorphisms: : RGD PMID:16533241 RGD:8552663 NCBI chr 8:67,947,527...67,955,296
Ensembl chr 8:67,947,510...67,955,236
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23564646 NCBI chr 2:75,505,857...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Ninj1 ninjurin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr13:49,341,005...49,349,727
Ensembl chr13:49,340,961...49,349,720
JBrowse link
G Numa1 nuclear mitotic apparatus protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr 7:101,583,169...101,664,166
Ensembl chr 7:101,583,318...101,664,171
JBrowse link
G Ogg1 8-oxoguanine DNA-glycosylase 1 IMP RGD PMID:15677345 RGD:8657146 NCBI chr 6:113,303,871...113,311,838
Ensembl chr 6:113,303,933...113,312,029
JBrowse link
G Phlda1 pleckstrin homology like domain, family A, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr10:111,342,147...111,344,510
Ensembl chr10:111,342,147...111,344,506
JBrowse link
G Pim1 proviral integration site 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr17:29,709,759...29,715,085
Ensembl chr17:29,709,727...29,715,086
JBrowse link
G Plat plasminogen activator, tissue ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860
JBrowse link
G Prdx4 peroxiredoxin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr  X:154,106,914...154,125,268
Ensembl chr  X:154,106,914...154,123,750
JBrowse link
G Qpct glutaminyl-peptide cyclotransferase (glutaminyl cyclase) ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr17:79,359,335...79,397,807
Ensembl chr17:79,359,335...79,397,807
JBrowse link
G Rab32 RAB32, member RAS oncogene family ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr10:10,420,783...10,433,951
Ensembl chr10:10,420,746...10,434,009
JBrowse link
G Rgs1 regulator of G-protein signaling 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr 1:144,120,407...144,124,862
Ensembl chr 1:144,118,034...144,124,980
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr  X:153,996,122...153,999,445
Ensembl chr  X:153,996,128...153,999,445
JBrowse link
G Sele selectin, endothelial cell ISO CTD Direct Evidence: marker/mechanism CTD PMID:17597826 NCBI chr 1:163,867,200...163,886,056
Ensembl chr 1:163,875,803...163,885,246
JBrowse link
G Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr 6:122,704,768...122,779,322
Ensembl chr 6:122,704,768...122,778,599
JBrowse link
G Slc7a5 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr 8:122,607,885...122,634,425
Ensembl chr 8:122,607,889...122,634,433
JBrowse link
G Socs1 suppressor of cytokine signaling 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr16:10,601,672...10,603,400
Ensembl chr16:10,600,104...10,603,400
JBrowse link
G Socs2 suppressor of cytokine signaling 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr10:95,219,765...95,253,176
Ensembl chr10:95,221,224...95,253,042
JBrowse link
G Spp1 secreted phosphoprotein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14555839 NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916
JBrowse link
G St6gal1 beta galactoside alpha 2,6 sialyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr16:23,043,478...23,179,100
Ensembl chr16:23,043,490...23,179,100
JBrowse link
G Stac src homology three (SH3) and cysteine rich domain ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr 9:111,386,476...111,519,673
Ensembl chr 9:111,390,505...111,519,416
JBrowse link
G Tap2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) susceptibility ISO RGD PMID:9303338 RGD:6482276 NCBI chr17:34,423,453...34,435,295
Ensembl chr17:34,422,501...34,435,295
JBrowse link
G Tlr4 toll-like receptor 4 ISO
IMP
RGD PMID:20711192 PMID:18725520 RGD:7777133, RGD:7794737 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521
JBrowse link
G Tlr7 toll-like receptor 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr  X:166,086,376...166,113,570
Ensembl chr  X:166,087,925...166,113,554
JBrowse link
G Tmsb10 thymosin, beta 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17597826 NCBI chr 6:72,934,330...72,935,731
Ensembl chr 6:72,934,330...72,935,731
JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:15849067 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnfaip6 tumor necrosis factor alpha induced protein 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 PMID:17374397 NCBI chr 2:51,928,125...51,946,693
Ensembl chr 2:51,928,021...51,946,698
JBrowse link
G Tslp thymic stromal lymphopoietin treatment IEP RGD PMID:30187507 RGD:38596345 NCBI chr18:32,948,436...32,952,852
Ensembl chr18:32,948,436...32,952,850
JBrowse link
G Upp1 uridine phosphorylase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr11:9,068,008...9,086,170
Ensembl chr11:9,068,103...9,086,170
JBrowse link
G Vegfa vascular endothelial growth factor A ISO mRNA:protein:skin: RGD PMID:7876550 PMID:7876550 RGD:7421586, RGD:7421586 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
JBrowse link
allergic cutaneous vasculitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csf3 colony stimulating factor 3 (granulocyte) treatment ISO associated with Severe Congenital Neutropenia; RGD PMID:20100783 RGD:11039037 NCBI chr11:98,591,287...98,594,457
Ensembl chr11:98,592,089...98,594,455
JBrowse link
allergic rhinitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A severity ISO DNA:snp:exon:c.1236C>T (human) RGD PMID:24040855 RGD:8657076 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
JBrowse link
G Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 no_association ISO DNA:deletion:intron:IVS16+1464-1751del (human) RGD PMID:15112973 RGD:8142345 NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 ISO mRNA, protein:increased expression:nasal mucosa (rat) RGD PMID:15362690 RGD:11522724 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Cat catalase ISO CTD Direct Evidence: marker/mechanism CTD PMID:29028686 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Ccl11 chemokine (C-C motif) ligand 11 treatment ISO RGD PMID:23089405 RGD:7248414 NCBI chr11:81,948,658...81,953,781
Ensembl chr11:81,948,649...81,953,781
JBrowse link
G Ccl26 chemokine (C-C motif) ligand 26 ISO protein:increased expression:oronasal secretion (human) RGD PMID:23883806 RGD:7364793 NCBI chr 5:135,589,302...135,592,423
Ensembl chr 5:135,589,302...135,592,423
JBrowse link
G Cd40 CD40 antigen ISO protein:increased expression:lymphocyte RGD PMID:19086656 RGD:8547782 NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868
JBrowse link
G Cd40lg CD40 ligand ISO protein:increased expression:lymphocyte RGD PMID:19086656 RGD:8547782 NCBI chr  X:56,257,503...56,269,402
Ensembl chr  X:56,257,503...56,269,402
JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 treatment IDA RGD PMID:10436391 RGD:11344920 NCBI chr 1:60,948,184...60,954,991
Ensembl chr 1:60,926,159...60,954,991
JBrowse link
G F2 coagulation factor II ISO protein:increased expression:nasal mucus RGD PMID:21711961 RGD:5147783 NCBI chr 2:91,442,742...91,466,802
Ensembl chr 2:91,455,665...91,466,759
JBrowse link
G Fcgr4 Fc receptor, IgG, low affinity IV susceptibility ISO DNA:polymorphism:exon:p.F158V(rs396991)(human) RGD PMID:18199088 RGD:5508449 NCBI chr 1:170,846,495...170,857,330
Ensembl chr 1:170,846,489...170,857,330
JBrowse link
G H2-M3 histocompatibility 2, M region locus 3 ISO RGD PMID:20487636 RGD:5144132 NCBI chr17:37,581,094...37,585,376
Ensembl chr17:37,581,111...37,585,375
JBrowse link
G Hrh1 histamine receptor H1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23333628 NCBI chr 6:114,374,897...114,460,259
Ensembl chr 6:114,374,897...114,460,257
JBrowse link
G Ifng interferon gamma treatment ISO associated with Asthma RGD PMID:12787306 PMID:18510219 RGD:7829803, RGD:10755770 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Il10 interleukin 10 treatment ISO
IDA
RGD PMID:23883806 PMID:23253209 RGD:7364793, RGD:7364818 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Il13 interleukin 13 susceptibility
no_association
ISO DNA:polymorphism:exon:c. 2044G>A (human)
ClinVar Annotator: match by term: Allergic rhinitis
CTD Direct Evidence: marker/mechanism
DNA:missense mutation:cds:p.R130Q (rs20541) (human)
DNA:SNPs:promoter, cds:-1112C>T, p.R130Q (rs1800925, rs20541) (human)
DNA:SNP:promoter:-1512A>C (rs1881457) (human)
ClinVar
CTD
OMIM
RGD
PMID:10699178 PMID:12928861 PMID:15356556 PMID:15483090 PMID:15711639 More... RGD:4152796, RGD:8549518, RGD:8549516, RGD:8549501 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529
JBrowse link
G Il13ra2 interleukin 13 receptor, alpha 2 ISO protein:increased expression:serum RGD PMID:21462799 RGD:8549521 NCBI chr  X:146,166,474...146,214,982
Ensembl chr  X:146,166,472...146,212,188
JBrowse link
G Il17a interleukin 17A susceptibility ISO DNA:snp:promoter:c.-444A>G (human)
mRNA:increased expression:peripheral blood mononuclear cell (human)
RGD PMID:22507625 PMID:21535180 RGD:9068429, RGD:5147409 NCBI chr 1:20,801,129...20,804,720
Ensembl chr 1:20,801,129...20,804,720
JBrowse link
G Il18 interleukin 18 severity
no_association
ISO DNA:SNP:promoter:-137G>C (rs187238) (human)
DNA:SNP:promoter:-140C>G (rs360721) (human)
RGD PMID:22840759 PMID:22840759 RGD:8655914, RGD:8655914 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140
JBrowse link
G Il1b interleukin 1 beta ISO protein:increased expression:nasal mucus RGD PMID:7750009 RGD:7401199 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il2 interleukin 2 ISO RGD PMID:12592663 RGD:8662963 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
JBrowse link
G Il4 interleukin 4 treatment ISO RGD PMID:9893928 PMID:24620662 PMID:8908280 PMID:14653048 RGD:7829796, RGD:11522769, RGD:7829827, RGD:7829802 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
JBrowse link
G Il5 interleukin 5 treatment ISO RGD PMID:23934070 PMID:24620662 RGD:11354976, RGD:11522769 NCBI chr11:53,611,621...53,615,930
Ensembl chr11:53,611,621...53,615,933
JBrowse link
G Itgb2 integrin beta 2 treatment ISO RGD PMID:12046991 RGD:9698435 NCBI chr10:77,366,164...77,401,542
Ensembl chr10:77,366,086...77,401,542
JBrowse link
G Muc1 mucin 1, transmembrane severity ISO mRNA,protein:decreased expression:nasal mucosa RGD PMID:31425778 PMID:31425778 PMID:31425778 RGD:127345100, RGD:127345100, RGD:127345100 NCBI chr 3:89,136,363...89,140,688
Ensembl chr 3:89,136,364...89,140,688
JBrowse link
G Muc5ac mucin 5, subtypes A and C, tracheobronchial/gastric ISO mRNA, protein:increased expression:nasal cavity epithelium RGD PMID:22972875 RGD:7364746 NCBI chr 7:141,342,695...141,372,964
Ensembl chr 7:141,342,709...141,372,968
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 ISO mRNA:increased expression:nasal mucosa (human) RGD PMID:23858718 RGD:8547523 NCBI chr 8:89,373,943...89,415,103
Ensembl chr 8:89,373,943...89,415,102
JBrowse link
G Pon1 paraoxonase 1 severity ISO protein:decreased activity:plasma (human) RGD PMID:23406590 RGD:8547583 NCBI chr 6:5,168,090...5,193,987
Ensembl chr 6:5,168,090...5,193,946
JBrowse link
G Prkg1 protein kinase, cGMP-dependent, type I ISO protein:increased expression:nasal cavity epithelium RGD PMID:24012634 RGD:7775060 NCBI chr19:30,541,887...31,742,667
Ensembl chr19:30,541,889...31,742,433
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16979129 NCBI chr 1:149,975,782...149,983,985
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Scgb1a1 secretoglobin, family 1A, member 1 (uteroglobin) IEP mRNA:decreased expression:nasal mucosa, lung RGD PMID:17882576 RGD:5144135 NCBI chr19:9,061,006...9,065,320
Ensembl chr19:9,061,000...9,065,322
JBrowse link
G Scgb3a2 secretoglobin, family 3A, member 2 susceptibility ISO DNA:SNP: :rs7726552 (human) RGD PMID:21410962 RGD:5144225 NCBI chr18:43,897,346...43,900,464
Ensembl chr18:43,897,354...43,900,464
JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 IEP mRNA:increased expression:nasal mucosa (mouse) RGD PMID:21339035 RGD:8547809 NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122
JBrowse link
G Tacr1 tachykinin receptor 1 ISO mRNA:increased expression:nasal mucosa RGD PMID:12768696 RGD:5147835 NCBI chr 6:82,378,990...82,537,085
Ensembl chr 6:82,379,315...82,537,085
JBrowse link
G Tgfb1 transforming growth factor, beta 1 treatment ISO RGD PMID:31368266 RGD:14995445 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Tlr2 toll-like receptor 2 severity ISO
IDA
DNA:polymorphism:cds:p.R753Q(human)
protein:increased expression:neutrophil:
mRNA:decreased expression:nasal mucosa:
RGD PMID:22402138 PMID:22555057 PMID:18381801 PMID:18219831 RGD:7800732, RGD:8552993, RGD:8552972, RGD:7800742 NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074
JBrowse link
G Tlr4 toll-like receptor 4 severity
treatment
susceptibility
no_association
ISO DNA:polymorphism:cds:p.D299G(human)
protein:increased expression:nasal lavage,leukocyte, bone marrow:
protein:decreased expression:nasal mucosa:
DNA:SNP: :rs1927911(human)
DNA:polymorphism: :4216G>C(human)
RGD PMID:22402138 PMID:22555057 PMID:22577387 PMID:17069098 PMID:23639307 More... RGD:7800732, RGD:8552993, RGD:7800740, RGD:7800738, RGD:7800736, RGD:4145354 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521
JBrowse link
G Tlr9 toll-like receptor 9 ISO protein:decreased expression:nasal mucosa: RGD PMID:22577387 RGD:7800740 NCBI chr 9:106,099,797...106,104,075
Ensembl chr 9:106,099,797...106,104,082
JBrowse link
Allergic Rhinoconjunctivitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 treatment ISO associated with Eosinophilic Esophagitis; DNA:polymorphisms:: RGD PMID:26416193 RGD:11352743 NCBI chr19:39,378,000...39,451,547
Ensembl chr19:39,378,000...39,451,519
JBrowse link
G Cyp2c66 cytochrome P450, family 2, subfamily c, polypeptide 66 treatment ISO associated with Eosinophilic Esophagitis; DNA:polymorphisms:: RGD PMID:26416193 RGD:11352743 NCBI chr19:39,102,342...39,175,200
Ensembl chr19:39,102,342...39,175,516
JBrowse link
G Il3 interleukin 3 susceptibility ISO DNA:SNP: :rs40401(human) RGD PMID:23953855 RGD:13506915 NCBI chr11:54,155,911...54,158,105
Ensembl chr11:54,156,129...54,158,103
JBrowse link
Anaphylaxis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenergic receptor, beta 1 disease_progression ISO RGD PMID:20959119 RGD:6893644 NCBI chr19:56,710,549...56,713,582
Ensembl chr19:56,710,631...56,721,545
JBrowse link
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) ISO RGD PMID:1422942 RGD:8548893 NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445
JBrowse link
G Aspg asparaginase ISO CTD Direct Evidence: marker/mechanism CTD PMID:65671 NCBI chr12:112,073,117...112,094,007
Ensembl chr12:112,073,113...112,093,993
JBrowse link
G Btk Bruton agammaglobulinemia tyrosine kinase treatment ISO RGD PMID:22228807 RGD:11040701 NCBI chr  X:133,443,083...133,484,366
Ensembl chr  X:133,443,085...133,484,319
JBrowse link
G Cabs1 calcium binding protein, spermatid specific 1 treatment ISO RGD PMID:25632019 RGD:14400306 NCBI chr 5:88,127,310...88,129,400
Ensembl chr 5:88,127,298...88,129,403
JBrowse link
G Cma1 chymase 1, mast cell ISO protein:increased expression:lung, mast cell (human) RGD PMID:17081716 RGD:5128820 NCBI chr14:56,178,908...56,182,132
Ensembl chr14:56,178,908...56,182,132
JBrowse link
G Fcgr3 Fc receptor, IgG, low affinity III susceptibility ISO associated with Agammaglobulinemia;DNA:mutation:splice junction: RGD PMID:23545275 PMID:26396093 RGD:11040993, RGD:11040995 NCBI chr 1:170,878,738...170,893,476
Ensembl chr 1:170,878,743...170,892,504
JBrowse link
G Grap2 GRB2-related adaptor protein 2 ameliorates IMP RGD PMID:18664516 RGD:126790488 NCBI chr15:80,456,798...80,537,055
Ensembl chr15:80,456,795...80,537,055
JBrowse link
G Hdac3 histone deacetylase 3 IMP RGD PMID:24619412 RGD:9590165 NCBI chr18:38,070,024...38,088,073
Ensembl chr18:38,068,897...38,088,069
JBrowse link
G Hp haptoglobin ISO RGD PMID:12147031 RGD:11041789 NCBI chr 8:110,301,760...110,305,804
Ensembl chr 8:110,301,760...110,305,804
JBrowse link
G Il4 interleukin 4 IEP
ISO
mRNA:increased expression:lung, intestine, spleen
associated with cystic echinococcosis; protein:increased expression:blood
RGD PMID:24468678 PMID:28095662 RGD:10402796, RGD:14696684 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
JBrowse link
G Kng2 kininogen 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:7623993 NCBI chr16:22,804,602...22,847,851
Ensembl chr16:22,804,604...22,848,232
JBrowse link
G Ltb4r1 leukotriene B4 receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10934231 NCBI chr14:56,003,419...56,005,949
Ensembl chr14:56,003,419...56,005,951
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19767079 NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO RGD PMID:18480553 RGD:2300247 NCBI chr 2:36,106,758...36,142,287
Ensembl chr 2:36,120,438...36,142,284
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO
IMP
RGD PMID:18480553 PMID:17822719 RGD:2300247, RGD:1642600 NCBI chr 1:149,975,782...149,983,985
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 ISO RGD PMID:21604443 RGD:7207802 NCBI chr 3:115,903,669...115,923,337
Ensembl chr 3:115,903,598...115,923,337
JBrowse link
G Wfdc6a WAP four-disulfide core domain 6A ISO CTD Direct Evidence: marker/mechanism CTD PMID:20693069 NCBI chr 2:164,421,439...164,427,704
Ensembl chr 2:164,421,439...164,427,367
JBrowse link
angioedema term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:8458210 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461
JBrowse link
G F12 coagulation factor XII (Hageman factor) ISO DNA:missense:exon:T309K,T309R
ClinVar Annotator: match by term: Angioedema
ClinVar
RGD
PMID:16638441 PMID:25741868 PMID:16638441 RGD:1601106 NCBI chr13:55,565,771...55,574,617
Ensembl chr13:55,565,771...55,574,606
JBrowse link
G H2-Ab1 histocompatibility 2, class II antigen A, beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15784113 NCBI chr17:34,482,201...34,488,392
Ensembl chr17:34,476,663...34,488,393
JBrowse link
G H2-Eb1 histocompatibility 2, class II antigen E beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:15784113 NCBI chr17:34,524,841...34,535,648
Ensembl chr17:34,524,841...34,535,648
JBrowse link
G Plat plasminogen activator, tissue ISO CTD Direct Evidence: marker/mechanism CTD PMID:16184341 PMID:18453163 PMID:20547619 NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860
JBrowse link
G Serping1 serine (or cysteine) peptidase inhibitor, clade G, member 1 susceptibility ISO DNA:mutations:exon
ClinVar Annotator: match by term: Angioedema
ClinVar
RGD
PMID:12402344 RGD:1600545 NCBI chr 2:84,595,704...84,605,778
Ensembl chr 2:84,595,731...84,605,788
JBrowse link
G Slc34a1 solute carrier family 34 (sodium phosphate), member 1 ISO ClinVar Annotator: match by term: Angioedema ClinVar PMID:16638441 PMID:25741868 NCBI chr13:55,547,435...55,562,508
Ensembl chr13:55,546,000...55,563,405
JBrowse link
G Sytl2 synaptotagmin-like 2 ISO ClinVar Annotator: match by term: Angioedema ClinVar PMID:28327206 NCBI chr 7:89,951,421...90,059,927
Ensembl chr 7:89,951,460...90,059,927
JBrowse link
G Xpnpep2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound ISO CTD Direct Evidence: marker/mechanism CTD PMID:16175507 NCBI chr  X:47,195,790...47,225,859
Ensembl chr  X:47,197,602...47,225,858
JBrowse link
arthus reaction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btk Bruton agammaglobulinemia tyrosine kinase treatment ISO RGD PMID:22228807 RGD:11040701 NCBI chr  X:133,443,083...133,484,366
Ensembl chr  X:133,443,085...133,484,319
JBrowse link
G Cfd complement factor D (adipsin) ISO RGD PMID:10605043 RGD:1624328 NCBI chr10:79,726,687...79,728,489
Ensembl chr10:79,726,687...79,728,489
JBrowse link
G Cx3cr1 chemokine (C-X3-C motif) receptor 1 IMP RGD PMID:23470165 RGD:9068463 NCBI chr 9:119,877,749...119,897,362
Ensembl chr 9:119,730,682...119,898,945
JBrowse link
G Fcgr3 Fc receptor, IgG, low affinity III treatment ISO RGD PMID:10762218 RGD:9588604 NCBI chr 1:170,878,738...170,893,476
Ensembl chr 1:170,878,743...170,892,504
JBrowse link
aspergillosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor ISO DNA:SNP:promoter:-374T>A (human) RGD PMID:22114731 RGD:8695981 NCBI chr17:34,816,545...34,819,911
Ensembl chr17:34,816,836...34,819,910
JBrowse link
G Ccl19 chemokine (C-C motif) ligand 19 IEP associated with Neutropenia;mRNA:increased expression:lung RGD PMID:19783686 RGD:5130908 NCBI chr 4:42,754,525...42,756,365
Ensembl chr 4:42,754,525...42,756,577
JBrowse link
G Ccr7 chemokine (C-C motif) receptor 7 IMP associated with Neutropenia RGD PMID:19783686 RGD:5130908 NCBI chr11:99,035,025...99,045,903
Ensembl chr11:99,035,022...99,045,903
JBrowse link
G Cd209d CD209d antigen ISO RGD PMID:21381282 RGD:5131183 NCBI chr 8:3,921,824...3,928,548
Ensembl chr 8:3,921,824...3,928,555
JBrowse link
G Cftr cystic fibrosis transmembrane conductance regulator severity IMP RGD PMID:22135344 RGD:35673332 NCBI chr 6:18,170,686...18,322,769
Ensembl chr 6:18,170,686...18,322,767
JBrowse link
G Clec1a C-type lectin domain family 1, member a susceptibility ISO ClinVar Annotator: match by term: Aspergillosis, susceptibility to
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
PMID:29489751 NCBI chr 6:129,403,647...129,428,963
Ensembl chr 6:129,401,735...129,428,963
JBrowse link
G Clec7a C-type lectin domain family 7, member a susceptibility ISO ClinVar Annotator: match by term: Aspergillosis, susceptibility to
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
PMID:19864674 PMID:20807886 PMID:24033266 NCBI chr 6:129,438,554...129,449,748
Ensembl chr 6:129,438,554...129,449,742
JBrowse link
G Crp C-reactive protein, pentraxin-related treatment ISO RGD PMID:20879853 RGD:9495929 NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598
JBrowse link
G Il15 interleukin 15 ISO DNA:polymorphism (human) RGD PMID:16893395 RGD:4981337 NCBI chr 8:83,058,253...83,129,883
Ensembl chr 8:83,058,261...83,129,851
JBrowse link
G Mbl1 mannose-binding lectin (protein A) 1 susceptibility IMP RGD PMID:20064561 RGD:8694071 NCBI chr14:40,873,413...40,885,861
Ensembl chr14:40,873,415...40,881,558
JBrowse link
G Mbl2 mannose-binding lectin (protein C) 2 susceptibility IMP RGD PMID:20064561 RGD:8694071 NCBI chr19:30,210,306...30,217,087
Ensembl chr19:30,210,342...30,217,087
JBrowse link
G S100b S100 protein, beta polypeptide, neural ISO DNA:SNP: :427C>T (human) RGD PMID:22114731 RGD:8695981 NCBI chr10:76,089,670...76,097,153
Ensembl chr10:76,089,687...76,096,993
JBrowse link
G Tlr1 toll-like receptor 1 susceptibility ISO DNA:SNPs: :p.R80T, p.N248S (human) RGD PMID:16461792 RGD:4889535 NCBI chr 5:65,082,023...65,090,945
Ensembl chr 5:65,082,022...65,090,906
JBrowse link
G Tlr2 toll-like receptor 2 IEP mRNA:increased expression:lung RGD PMID:19781388 RGD:4145322 NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074
JBrowse link
G Tlr6 toll-like receptor 6 susceptibility ISO DNA:SNP: :p.S249P (human) RGD PMID:16461792 RGD:4889535 NCBI chr 5:65,109,379...65,128,387
Ensembl chr 5:65,109,374...65,117,440
JBrowse link
aspirin-induced respiratory disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacng6 calcium channel, voltage-dependent, gamma subunit 6 susceptibility ISO DNA:SNP,haplotype:rs192808(human) RGD PMID:20860846 RGD:13524562 NCBI chr 7:3,472,017...3,484,183
Ensembl chr 7:3,472,711...3,484,183
JBrowse link
G Ccr3 chemokine (C-C motif) receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:20485159 PMID:20022477 RGD:4145619 NCBI chr 9:123,817,799...123,831,729
Ensembl chr 9:123,822,009...123,831,726
JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16502481 PMID:17641958 PMID:20485159 NCBI chr  X:105,617,952...105,647,329
Ensembl chr  X:105,617,952...105,647,285
JBrowse link
G Cysltr2 cysteinyl leukotriene receptor 2 ISO DNA:SNPs: :-819T>G, 2078C>T, 2534A>G (human)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:16502481 PMID:20485159 PMID:15970796 RGD:5144000 NCBI chr14:73,263,515...73,286,554
Ensembl chr14:73,263,043...73,286,554
JBrowse link
G Fancc Fanconi anemia, complementation group C ISO DNA:haplotype::rs4647416(human) RGD PMID:21670957 RGD:11045795 NCBI chr13:63,452,519...63,645,126
Ensembl chr13:63,432,857...63,645,092
JBrowse link
G H2-Aa histocompatibility 2, class II antigen A, alpha susceptibility ISO RGD PMID:25975240 RGD:11074090 NCBI chr17:34,501,718...34,506,797
Ensembl chr17:34,501,718...34,506,797
JBrowse link
G H2-Ab1 histocompatibility 2, class II antigen A, beta 1 susceptibility ISO RGD PMID:25975240 RGD:11074090 NCBI chr17:34,482,201...34,488,392
Ensembl chr17:34,476,663...34,488,393
JBrowse link
G H2-Eb1 histocompatibility 2, class II antigen E beta susceptibility ISO RGD PMID:25975240 RGD:11074090 NCBI chr17:34,524,841...34,535,648
Ensembl chr17:34,524,841...34,535,648
JBrowse link
G Il4 interleukin 4 susceptibility ISO DNA:SNPs:promoter,5'UTR,intron:multiple RGD PMID:20921925 RGD:11528633 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
JBrowse link
G Ltc4s leukotriene C4 synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:9393345 PMID:9466979 PMID:10970818 PMID:20485159 NCBI chr11:50,127,288...50,129,378
Ensembl chr11:50,127,288...50,129,443
JBrowse link
G Ms4a2 membrane-spanning 4-domains, subfamily A, member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16502481 NCBI chr19:11,592,881...11,601,154
Ensembl chr19:11,592,887...11,601,083
JBrowse link
G Postn periostin, osteoblast specific factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:18391768 NCBI chr 3:54,266,688...54,298,462
Ensembl chr 3:54,268,530...54,298,458
JBrowse link
G Ptgdr2 prostaglandin D2 receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20485159 NCBI chr19:10,901,883...10,919,875
Ensembl chr19:10,914,524...10,919,875
JBrowse link
G Ptger2 prostaglandin E receptor 2 (subtype EP2) ISO ClinVar Annotator: match by term: Asthma, aspirin-induced, susceptibility to
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
PMID:15496426 PMID:16502481 NCBI chr14:45,225,568...45,241,277
Ensembl chr14:45,225,652...45,241,277
JBrowse link
G Ptgir prostaglandin I receptor (IP) ISO CTD Direct Evidence: marker/mechanism CTD PMID:20485159 NCBI chr 7:16,640,415...16,644,830
Ensembl chr 7:16,640,415...16,644,830
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO protein:increased expression:mast cell
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:16502481 PMID:20485159 PMID:9487340 RGD:5143936 NCBI chr 1:149,975,782...149,983,985
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Tap2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) ISO RGD PMID:21796142 RGD:5147839 NCBI chr17:34,423,453...34,435,295
Ensembl chr17:34,422,501...34,435,295
JBrowse link
G Tbx21 T-box 21 ISO ClinVar Annotator: match by term: Asthma, aspirin-induced, susceptibility to
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
PMID:15806396 PMID:16502481 NCBI chr11:96,988,833...97,006,157
Ensembl chr11:96,988,897...97,006,157
JBrowse link
G Tbxa2r thromboxane A2 receptor susceptibility ISO DNA:polymorphism: :795T>C (human)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:16502481 PMID:20485159 PMID:15898979 RGD:11059537 NCBI chr10:81,164,102...81,171,008
Ensembl chr10:81,164,565...81,171,006
JBrowse link
asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A ISO protein:increased expression:blood, lymphocyte RGD PMID:19484671 RGD:4890020 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
JBrowse link
G Abcc1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 IMP RGD PMID:18931056 RGD:5128825 NCBI chr16:14,179,317...14,292,743
Ensembl chr16:14,179,422...14,293,601
JBrowse link
G Abo ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase, transferase B, alpha 1-3-galactosyltransferase) no_association ISO RGD PMID:16008680 PMID:19771478 RGD:5128831, RGD:5128835 NCBI chr 2:26,732,508...26,755,007
Ensembl chr 2:26,732,515...26,754,991
JBrowse link
G Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 susceptibility ISO DNA:polymorphism (human) RGD PMID:19383228 PMID:19484664 RGD:4140919, RGD:4140913 NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 ISO DNA:hypermethylation:promoter RGD PMID:19221603 RGD:13831295 NCBI chr 1:78,635,542...78,685,460
Ensembl chr 1:78,635,542...78,685,460
JBrowse link
G Ada adenosine deaminase susceptibility ISO DNA:polymorphisms (human) RGD PMID:16754522 RGD:5128848 NCBI chr 2:163,568,491...163,592,161
Ensembl chr 2:163,568,504...163,592,159
JBrowse link
G Adam33 a disintegrin and metallopeptidase domain 33 susceptibility
no_association
disease_progression
ISO
IEP
DNA:SNPs: :multiple (human)
DNA:SNPs:introns,exon:7575G>A, 11188A>T, 12433T>C (human)
mRNA:increased expression:bronchus
DNA:polymorphism: :p.M764T (human)
mRNA:increased expression:lung
DNA:SNPs (human)
RGD
GAD
PMID:18778489 PMID:15118671 PMID:16893396 PMID:17339047 PMID:17961406 More... RGD:4145378, RGD:1331525, RGD:4145382, RGD:4145380, RGD:4145379, RGD:4145360, RGD:4145359 NCBI chr 2:130,892,739...130,905,734
Ensembl chr 2:130,892,511...130,905,734
JBrowse link
G Adam8 a disintegrin and metallopeptidase domain 8 severity ISO
IEP
IMP
mRNA:increased expression:bronchus
mRNA:increased expression:respiratory tract
RGD PMID:17339047 PMID:19373511 PMID:20194813 RGD:4145380, RGD:5128878, RGD:5128872 NCBI chr 7:139,558,845...139,573,016
Ensembl chr 7:139,558,845...139,572,475
JBrowse link
G Adcy2 adenylate cyclase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chr13:68,768,162...69,147,719
Ensembl chr13:68,768,162...69,147,660
JBrowse link
G Adcyap1r1 adenylate cyclase activating polypeptide 1 receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21059121 NCBI chr 6:55,428,486...55,478,440
Ensembl chr 6:55,428,963...55,478,436
JBrowse link
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide susceptibility ISO
IMP
protein:increased expression:respiratory system fluid/secretion
DNA:SNPs: :rs1154404, rs28730619 (human)
RGD PMID:19514054 PMID:19395503 PMID:17543375 PMID:15919956 RGD:5128890, RGD:5128891, RGD:5128882, RGD:5128892 NCBI chr 3:138,142,961...138,161,260
Ensembl chr 3:138,148,854...138,161,260
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing IMP RGD PMID:19168697 RGD:5686821 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778
JBrowse link
G Adora1 adenosine A1 receptor ISO
IMP
DNA:SNPs: :1405C>T (human)
protein:increased expression:bronchus
RGD PMID:19019667 PMID:20400685 PMID:17959644 RGD:4890386, RGD:4145444, RGD:5129097 NCBI chr 1:134,126,953...134,163,195
Ensembl chr 1:134,126,961...134,163,169
JBrowse link
G Adora2a adenosine A2a receptor ISO
IMP
IDA
IEP
DNA:SNP (human)
mRNA:decreased expression:aorta
RGD PMID:19019667 PMID:17293374 PMID:16339780 PMID:18310516 RGD:4890386, RGD:4890380, RGD:4890385, RGD:4890366 NCBI chr10:75,152,711...75,170,626
Ensembl chr10:75,152,711...75,170,618
JBrowse link
G Adrb2 adrenergic receptor, beta 2 susceptibility ISO
IMP
ClinVar Annotator: match by term: Beta-2-adrenoreceptor agonist, reduced response to
CTD Direct Evidence: marker/mechanism
DNA:SNP: :-1023A>G (human)
DNA:SNPs: :p.R16G, p.Q27E (human)
DNA:polymorphism: :p.R16G (human)
DNA:SNPs:promoter:multiple (human)
DNA:SNP: :p.Q27E (human)
ClinVar
CTD
OMIM
RGD
PMID:8383511 PMID:15284533 PMID:16596417 PMID:1655856 PMID:15118671 More... RGD:5129113, RGD:1331525, RGD:4145081, RGD:4145094, RGD:4145092, RGD:4145108, RGD:4145105, RGD:4145061, RGD:4145096, RGD:4145107 NCBI chr18:62,310,784...62,313,052
Ensembl chr18:62,310,887...62,313,030
JBrowse link
G Ager advanced glycosylation end product-specific receptor treatment
onset
ISO CTD Direct Evidence: marker/mechanism
protein:decreased expression:lung (rat)
CTD
RGD
PMID:23304218 PMID:33075463 PMID:21920897 PMID:23304218 RGD:7244279, RGD:6767554, RGD:7244279 NCBI chr17:34,816,545...34,819,911
Ensembl chr17:34,816,836...34,819,910
JBrowse link
G Agtr1a angiotensin II receptor, type 1a IMP
ISO
RGD PMID:17877756 PMID:19080339 RGD:5147452, RGD:5147457 NCBI chr13:30,520,339...30,566,850
Ensembl chr13:30,520,424...30,566,850
JBrowse link
G Agtr2 angiotensin II receptor, type 2 ISO mRNA, protein:increased expression:lung RGD PMID:19080339 RGD:5147457 NCBI chr  X:21,350,863...21,355,072
Ensembl chr  X:21,350,783...21,355,403
JBrowse link
G Aldh2 aldehyde dehydrogenase 2, mitochondrial ISO CTD Direct Evidence: marker/mechanism CTD PMID:9600491 PMID:11506308 PMID:15118671 RGD:1331525 NCBI chr 5:121,704,090...121,731,887
Ensembl chr 5:121,704,090...121,731,887
JBrowse link
G Alox15 arachidonate 15-lipoxygenase IEP
IMP
protein:increased expression:lung RGD PMID:19628725 PMID:18692885 RGD:5509605, RGD:5509784 NCBI chr11:70,234,973...70,279,465
Ensembl chr11:70,234,978...70,242,857
JBrowse link
G Alox5 arachidonate 5-lipoxygenase no_association
susceptibility
treatment
severity
ISO
IMP
IEP
IDA
DNA:polymorphism:promoter (human)
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:blood, leukocyte
protein:increased expression:lung
DNA:repeat:promoter (human)
DNA:polymorphism:cds:p.E254K (human)
CTD
OMIM
RGD
PMID:20128419 PMID:10369259 PMID:9642160 PMID:12911785 PMID:8879219 More... RGD:4890407, RGD:734557, RGD:5147467, RGD:5147465, RGD:5147462, RGD:4890422, RGD:4890408, RGD:4890415, RGD:4890410, RGD:4890413 NCBI chr 6:116,387,030...116,438,139
Ensembl chr 6:116,387,038...116,438,139
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein susceptibility
no_association
ISO
IMP
IEP
DNA:SNP: :rs10507391 (human)
mRNA:increased expression:blood, leukocyte
DNA:repeat:promoter:-169(A)21 (human)
DNA:substitution, repeat:promoter:-336G>A, -169(A)19-23 (human)
DNA:polymorphisms:intron:IVS2+12C>A, IVS2+105T>C (human)
protein:increased expression:lung
DNA:polymorphism:promoter (human)
DNA:SNPs (human)
RGD PMID:20067482 PMID:9642160 PMID:10527888 PMID:12911785 PMID:15784112 More... RGD:4890405, RGD:5147467, RGD:5147466, RGD:5147465, RGD:5147464, RGD:5147462, RGD:4890422, RGD:4890407, RGD:4890409 NCBI chr 5:149,201,814...149,224,963
Ensembl chr 5:149,201,577...149,224,963
JBrowse link
G Ambp alpha 1 microglobulin/bikunin precursor ISO protein:increased expression:serum RGD PMID:14621078 RGD:6904149 NCBI chr 4:63,061,512...63,072,409
Ensembl chr 4:63,061,512...63,073,036
JBrowse link
G Ang angiogenin, ribonuclease, RNase A family, 5 severity ISO protein:increased expression:sputum RGD PMID:16478840 RGD:6892719 NCBI chr14:51,328,534...51,339,466
Ensembl chr14:51,328,607...51,339,466
JBrowse link
G Anxa1 annexin A1 IMP RGD PMID:22092555 RGD:7421657 NCBI chr19:20,350,798...20,368,035
Ensembl chr19:20,350,792...20,368,308
JBrowse link
G Areg amphiregulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:15696081 NCBI chr 5:91,287,458...91,296,291
Ensembl chr 5:91,287,458...91,296,291
JBrowse link
G Arg1 arginase, liver ISO
IEP
DNA:SNP: :rs2781667 (human)
CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:lung, mononuclear cell (human)
mRNA:increased expression:lung (mouse)
CTD
RGD
PMID:19281908 PMID:19800904 PMID:20124949 PMID:12813022 PMID:12813022 RGD:5129205, RGD:4143187, RGD:4143187 NCBI chr10:24,791,105...24,803,368
Ensembl chr10:24,791,119...24,803,382
JBrowse link
G Arg2 arginase type II severity
susceptibility
ISO
IEP
DNA:SNP: :rs3742879, rs17249437 (human)
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:lung (mouse)
DNA:SNPs (human)
CTD
RGD
PMID:19281908 PMID:20124949 PMID:12813022 PMID:16387594 RGD:5129205, RGD:4143187, RGD:5129207 NCBI chr12:79,177,562...79,203,075
Ensembl chr12:79,177,551...79,203,075
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18357729 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bdkrb2 bradykinin receptor, beta 2 onset ISO DNA:polymorphism:exon (human)
protein:increased expression:blood, eosinophil
RGD PMID:11517947 PMID:8856156 PMID:14727005 PMID:19038786 RGD:4890456, RGD:4891042, RGD:4890454, RGD:4891028 NCBI chr12:105,529,431...105,561,503
Ensembl chr12:105,529,485...105,561,496
JBrowse link
G Bdnf brain derived neurotrophic factor susceptibility
severity
ISO protein:decreased expression:blood, eosinophil
DNA:SNP,haplotypes: :rs10767664,rs12273539,rs962369(human)
DNA:polymorphisms: :p.V66M, -270C>T (human)
protein:increased expression:plasma
DNA:polymorphisms: :p.V66M (rs6265) (human)
RGD PMID:12752594 PMID:21723144 PMID:17584309 PMID:20874832 PMID:19895626 More... RGD:4891122, RGD:8655967, RGD:4891067, RGD:4891063, RGD:4891117, RGD:4891123 NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352
JBrowse link
G Bglap bone gamma carboxyglutamate protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:8429434 NCBI chr 3:88,290,802...88,291,773
Ensembl chr 3:88,290,808...88,291,771
JBrowse link
G Bmpr1b bone morphogenetic protein receptor, type 1B ISO protein:decreased expression:bronchus RGD PMID:18292470 RGD:5129470 NCBI chr 3:141,540,230...141,875,335
Ensembl chr 3:141,542,897...141,875,186
JBrowse link
G Bmpr2 bone morphogenetic protein receptor, type II (serine/threonine kinase) ISO protein:decreased expression:bronchus RGD PMID:18292470 RGD:5129470 NCBI chr 1:59,802,721...59,917,240
Ensembl chr 1:59,802,559...59,918,173
JBrowse link
G C3 complement component 3 severity IMP
ISO
IEP
protein:increased expression:serum
DNA:SNP:intron:rs11569562 (human)
DNA:SNP: :4896C>T (human)
protein:increased expression:respiratory system fluid/secretion
Interaction with IL4RA
DNA:SNPs: :multiple (human)
RGD PMID:11591733 PMID:20589464 PMID:18566738 PMID:15278436 PMID:20802484 More... RGD:5129517, RGD:5129519, RGD:5129501, RGD:5129512, RGD:5129681, RGD:5129537, RGD:5129538, RGD:5129505 NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136
JBrowse link
G C3ar1 complement component 3a receptor 1 severity ISO
IMP
IEP
mRNA:increased expression:lung
protein:increased expression:lung, leukocyte
RGD PMID:15278436 PMID:20802484 PMID:20045013 PMID:17544263 PMID:15940127 More... RGD:5129512, RGD:5129681, RGD:5129686, RGD:5129560, RGD:5129561, RGD:5129560 NCBI chr 6:122,824,099...122,833,116
Ensembl chr 6:122,824,097...122,833,120
JBrowse link
G C5ar1 complement component 5a receptor 1 severity IMP
IEP
ISO
protein:increased expression:lung, leukocyte
protein:increased expression:respiratory tract
RGD PMID:16511606 PMID:20802484 PMID:17544263 PMID:15940127 RGD:5130166, RGD:5129681, RGD:5129560, RGD:5129561 NCBI chr 7:15,980,668...15,993,465
Ensembl chr 7:15,980,668...15,993,465
JBrowse link
G Card11 caspase recruitment domain family, member 11 susceptibility IMP RGD PMID:16751370 RGD:11100037 NCBI chr 5:140,858,754...140,986,351
Ensembl chr 5:140,858,745...140,986,337
JBrowse link
G Carm1 coactivator-associated arginine methyltransferase 1 ISO mRNA:decreased expression:lung RGD PMID:20423833 RGD:9491823 NCBI chr 9:21,458,168...21,500,763
Ensembl chr 9:21,458,190...21,503,919
JBrowse link
G Casp1 caspase 1 ISO protein:increased expression:serum RGD PMID:12396474 RGD:5130192 NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290
JBrowse link
G Cat catalase severity ISO
IDA
DNA:polymorphism:promoter:-21A>T (human)
CTD Direct Evidence: marker/mechanism
protein:decreased activity
DNA:polymorphism:promoter:-262C>T (human)
protein:increased expression:erythrocyte
CTD
RGD
PMID:18048809 PMID:19373626 PMID:16622028 PMID:18048809 PMID:19475625 RGD:5130753, RGD:5130867, RGD:5130856, RGD:5130751 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Ccl1 chemokine (C-C motif) ligand 1 ISO protein:increased expression:respiratory system fluid/secretion RGD PMID:20455898 RGD:4891420 NCBI chr11:82,067,492...82,070,638
Ensembl chr11:82,067,483...82,196,516
JBrowse link
G Ccl11 chemokine (C-C motif) ligand 11 susceptibility
treatment
severity
ISO
IEP
IMP
protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism
DNA:polymorphism: :p.A23T (human)
mRNA:increased expression:lung
CTD
OMIM
RGD
PMID:16304252 PMID:22932891 PMID:17074272 PMID:17845580 PMID:20704746 More... RGD:5130930, RGD:7248416, RGD:4145461, RGD:4145457, RGD:4145387, RGD:4145392, RGD:4145451, RGD:4891485 NCBI chr11:81,948,658...81,953,781
Ensembl chr11:81,948,649...81,953,781
JBrowse link
G Ccl17 chemokine (C-C motif) ligand 17 ISO
IMP
IEP
IDA
mRNA:increased expression:lung
protein:increased expression:respiratory system fluid/secretion
RGD PMID:15993846 PMID:11160256 PMID:20074456 PMID:15947487 PMID:20237293 RGD:2306304, RGD:4145603, RGD:4145487, RGD:4145513, RGD:4145486 NCBI chr 8:95,535,996...95,538,666
Ensembl chr 8:95,537,081...95,538,664
JBrowse link
G Ccl19 chemokine (C-C motif) ligand 19 ISO protein:increased expression:bronchus submucosa, mast cell RGD PMID:16959919 RGD:5130911 NCBI chr 4:42,754,525...42,756,365
Ensembl chr 4:42,754,525...42,756,577
JBrowse link
G Ccl2 chemokine (C-C motif) ligand 2 severity
treatment
ISO
IEP
IDA
protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:lung (mouse)
DNA:haplotype::-2518A>G (human)
protein:increased expression:lung
CTD
RGD
PMID:19373627 PMID:19373627 PMID:12055264 PMID:25441643 PMID:23454776 More... RGD:4891466, RGD:11528570, RGD:11528569, RGD:8551842, RGD:2307055, RGD:4145509 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Ccl20 chemokine (C-C motif) ligand 20 ISO protein:increased expression:respiratory system fluid/secretion
associated with Allergic Rhinitis;protein:increased expression:serum
RGD PMID:18422729 PMID:22469443 RGD:7483597, RGD:7483618 NCBI chr 1:83,094,487...83,096,888
Ensembl chr 1:83,094,487...83,096,888
JBrowse link
G Ccl22 chemokine (C-C motif) ligand 22 IMP
ISO
IEP
mRNA, protein:increased expression:respiratory system mucosa, respiratory system fluid/secretion
mRNA:increased expression:lung
protein:increased expression:respiratory system fluid/secretion
RGD PMID:10384142 PMID:18684970 PMID:15993846 PMID:18316417 RGD:4891475, RGD:4145489, RGD:2306304, RGD:4891474 NCBI chr 8:95,472,312...95,478,016
Ensembl chr 8:95,472,218...95,478,327
JBrowse link
G Ccl24 chemokine (C-C motif) ligand 24 susceptibility ISO
IMP
DNA:SNPs: :179T>C, 275C>T (human)
DNA:SNPs: :304C>A, 1272A>G (human)
protein:increased expression:respiratory system fluid/secretion
DNA:SNP: :1265A>G (human)
protein:increased expression:plasma
RGD PMID:15207712 PMID:17548626 PMID:18712274 PMID:12952266 PMID:12761043 More... RGD:4891495, RGD:4891484, RGD:4891483, RGD:4891496, RGD:5130932, RGD:4891485, RGD:5130930 NCBI chr 5:135,598,789...135,601,977
Ensembl chr 5:135,598,791...135,601,903
JBrowse link
G Ccl26 chemokine (C-C motif) ligand 26 treatment ISO
IDA
protein:increased expression:plasma
DNA:SNPs: :77C>T, 2497T>G (human)
DNA:SNPs: :77C>T, 716A>G, 1579G>A (human)
RGD PMID:16304252 PMID:25399816 PMID:25530546 PMID:15207712 PMID:18712274 RGD:5130930, RGD:11087575, RGD:11081163, RGD:4891495, RGD:4891483 NCBI chr 5:135,589,302...135,592,423
Ensembl chr 5:135,589,302...135,592,423
JBrowse link
G Ccl27a chemokine (C-C motif) ligand 27A ISO RGD PMID:19541356 RGD:5130899 NCBI chr 4:41,769,467...41,774,251
Ensembl chr 4:41,769,467...41,774,247
JBrowse link
G Ccl28 chemokine (C-C motif) ligand 28 IEP mRNA:increased expression:lung (mouse) RGD PMID:16290206 RGD:4892195 NCBI chr13:120,085,355...120,115,895
Ensembl chr13:120,085,355...120,115,895
JBrowse link
G Ccl4 chemokine (C-C motif) ligand 4 ISO RGD PMID:18774390 RGD:5130915 NCBI chr11:83,553,410...83,555,509
Ensembl chr11:83,553,410...83,555,509
JBrowse link
G Ccl5 chemokine (C-C motif) ligand 5 susceptibility IEP
ISO
protein:increased expression:lung, secretion (mouse)
CTD Direct Evidence: marker/mechanism
protein:increased expression:smooth muscle cell
DNA:transition:5' utr:-403G>A (human)
CTD
RGD
PMID:8534483 PMID:20092989 PMID:18208670 PMID:20430255 RGD:4891430, RGD:2307112, RGD:4891381 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344
JBrowse link
G Ccl7 chemokine (C-C motif) ligand 7 ISO
IEP
RGD PMID:21388664 PMID:19965981 RGD:5130983, RGD:5130979 NCBI chr11:81,936,538...81,938,351
Ensembl chr11:81,936,538...81,938,351
JBrowse link
G Ccr1 chemokine (C-C motif) receptor 1 severity IEP
IMP
mRNA:increased expression:lung
associated with Respiratory Syncytial Virus Infections
RGD PMID:15654816 PMID:15593301 RGD:5688158, RGD:5688159 NCBI chr 9:123,762,163...123,768,729
Ensembl chr 9:123,762,161...123,768,729
JBrowse link
G Ccr2 chemokine (C-C motif) receptor 2 susceptibility ISO
IEP
DNA:SNP:cds:p.V64I (human)
DNA:haplotype:cds:p.V64I(human)
protein:increased expression:lung, dendritic cell (mouse)
RGD PMID:17298432 PMID:23454776 PMID:19917684 RGD:4145110, RGD:8551842, RGD:8549811 NCBI chr 9:123,901,954...123,913,594
Ensembl chr 9:123,901,987...123,913,594
JBrowse link
G Ccr3 chemokine (C-C motif) receptor 3 IMP
ISO
IDA
protein:increased expression:respiratory system fluid/secretion, neutrophil
DNA:SNP:exon:51T>C (human)
RGD PMID:18699933 PMID:19017998 PMID:17145927 PMID:16978084 PMID:20220260 More... RGD:4145633, RGD:4145632, RGD:1601020, RGD:4145646, RGD:4145638, RGD:4145623, RGD:4145618 NCBI chr 9:123,817,799...123,831,729
Ensembl chr 9:123,822,009...123,831,726
JBrowse link
G Ccr4 chemokine (C-C motif) receptor 4 ISO mRNA:increased expression:lung RGD PMID:15993846 RGD:2306304 NCBI chr 9:114,319,384...114,334,544
Ensembl chr 9:114,319,384...114,333,984
JBrowse link
G Ccr5 chemokine (C-C motif) receptor 5 no_association IMP
ISO
IEP
DNA:polymorphism, frameshift mutation: :-59029G>A, p.S185_T195del (rs333) (human)
mRNA:increased expression:lung (mouse)
protein:decreased expression:blood, lymphocyte (human)
DNA:frameshift mutation:cds:p.S185_T195del rs333 (human)
RGD PMID:16474097 PMID:23454776 PMID:18094012 PMID:15256090 PMID:20220260 RGD:4892093, RGD:8551842, RGD:4892088, RGD:4892108, RGD:4145638 NCBI chr 9:123,921,557...123,934,153
Ensembl chr 9:123,921,580...123,947,736
JBrowse link
G Ccr6 chemokine (C-C motif) receptor 6 IEP protein:increased expression:lung, dendritic cell (mouse) RGD PMID:19917684 RGD:8549811 NCBI chr17:8,454,875...8,477,353
Ensembl chr17:8,454,875...8,475,973
JBrowse link
G Ccr7 chemokine (C-C motif) receptor 7 IEP protein:increased expression:lung, dendritic cell (mouse) RGD PMID:19917684 RGD:8549811 NCBI chr11:99,035,025...99,045,903
Ensembl chr11:99,035,022...99,045,903
JBrowse link
G Ccr8 chemokine (C-C motif) receptor 8 ISO mRNA:increased expression:lung RGD PMID:15993846 RGD:2306304 NCBI chr 9:119,921,199...119,923,972
Ensembl chr 9:119,921,180...119,923,972
JBrowse link
G Ccr9 chemokine (C-C motif) receptor 9 ISO mRNA, protein:increased expression:blood, mature NK T cell RGD PMID:16210593 RGD:5130925 NCBI chr 9:123,596,276...123,612,522
Ensembl chr 9:123,507,504...123,613,395
JBrowse link
G Cd14 CD14 antigen severity
no_association
susceptibility
ISO DNA:polymorphism:promoter:c. -260C>T (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:promoter:c. -159C>T (human)
DNA:SNPs: :
protein:increased expression:serum|DNA:polymorphism:promoter:c. -159C>T (human)
CTD
RGD
PMID:17607003 PMID:15940135 PMID:15741437 PMID:19096003 PMID:18312481 More... RGD:4144814, RGD:4144815, RGD:4144228, RGD:4144208, RGD:4144813 NCBI chr18:36,858,117...36,859,868
Ensembl chr18:36,858,120...36,859,851
JBrowse link
G Cd1d1 CD1d1 antigen susceptibility IMP associated with fasciolopsiasis RGD PMID:20304473 RGD:4140417 NCBI chr 3:86,903,141...86,919,665
Ensembl chr 3:86,903,141...86,906,748
JBrowse link
G Cd209a CD209a antigen ISO RGD PMID:21471959 RGD:5131188 NCBI chr 8:3,793,395...3,798,984
Ensembl chr 8:3,793,397...3,798,984
JBrowse link
G Cd274 CD274 antigen treatment IMP associated with Chlamydia pneumonia RGD PMID:26378990 RGD:41412180 NCBI chr19:29,339,428...29,365,495
Ensembl chr19:29,344,855...29,365,495
JBrowse link
G Cd28 CD28 antigen ISO RGD PMID:21356099 RGD:5131612 NCBI chr 1:60,785,547...60,812,521
Ensembl chr 1:60,755,959...60,812,518
JBrowse link
G Cd40 CD40 antigen treatment ISO
IEP
RGD PMID:19220210 PMID:20205594 PMID:19159017 PMID:20941750 RGD:5132272, RGD:8547792, RGD:4144188, RGD:4892277 NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868
JBrowse link
G Cd40lg CD40 ligand severity IMP RGD PMID:9502776 RGD:11352238 NCBI chr  X:56,257,503...56,269,402
Ensembl chr  X:56,257,503...56,269,402
JBrowse link
G Cd80 CD80 antigen IEP RGD PMID:21051864 PMID:21440530 PMID:21352203 RGD:5132621, RGD:5132619, RGD:5132620 NCBI chr16:38,277,793...38,316,682
Ensembl chr16:38,275,923...38,316,697
JBrowse link
G Cd86 CD86 antigen treatment IEP
IMP
ISO
protein:increased expression:lung, alveolar macrophage (mouse)
protein:increased expression:blood, B cell (human)
protein:increased expression:lung, dendritic cell (rat)
DNA:snp:exon:p.I179V rs2681417 (human)
RGD PMID:20941750 PMID:25344652 PMID:9449507 PMID:20668438 PMID:9551945 More... RGD:4892277, RGD:11354965, RGD:4892555, RGD:4892199, RGD:4892202, RGD:4892280 NCBI chr16:36,389,318...36,486,439
Ensembl chr16:36,424,231...36,486,443
JBrowse link
G Cdh1 cadherin 1 ISO RGD PMID:21540309 RGD:5132878 NCBI chr 8:107,329,982...107,396,879
Ensembl chr 8:107,329,983...107,396,878
JBrowse link
G Cdhr3 cadherin-related family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24241537 NCBI chr12:33,083,781...33,142,900
Ensembl chr12:33,083,795...33,142,874
JBrowse link
G Cftr cystic fibrosis transmembrane conductance regulator susceptibility ISO DNA:deletion: :p.F508del(human) RGD PMID:20298391 RGD:4140387 NCBI chr 6:18,170,686...18,322,769
Ensembl chr 6:18,170,686...18,322,767
JBrowse link
G Chat choline acetyltransferase ISO Protein:decreased expression:lung epithelium RGD PMID:17328924 RGD:5686690 NCBI chr14:32,130,160...32,187,866
Ensembl chr14:32,130,160...32,187,946
JBrowse link
G Chia1 chitinase, acidic 1 no_association ISO
IMP
IEP
DNA:snps:5' utr, cds:multiple (human)
DNA:snps:multiple (human)
mRNA:increased expression:lung, epithelial cell (human)
mRNA:increased expression:lung (mouse)
RGD PMID:16179638 PMID:20226308 PMID:19548841 PMID:15192232 PMID:14734765 RGD:4996473, RGD:5024922, RGD:5024921, RGD:4985150, RGD:4990463 NCBI chr 3:106,020,698...106,039,434
Ensembl chr 3:106,020,545...106,039,436
JBrowse link
G Chil1 chitinase-like 1 susceptibility ISO human gene in mouse model
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Asthma-related traits, susceptibility to, 7
DNA:snp:5' utr:g.-131C>G rs4950928 (human)
protein:increased secretion:serum (human)
CTD
OMIM
ClinVar
RGD
PMID:18403759 PMID:19414556 PMID:19568425 PMID:18003958 RGD:4892663, RGD:4892630, RGD:4892632 NCBI chr 1:134,109,894...134,117,769
Ensembl chr 1:134,109,914...134,117,919
JBrowse link
G Chml choroideremia-like ISO RGD PMID:18343558 RGD:5133238 NCBI chr 1:175,509,803...175,515,919
Ensembl chr 1:175,509,803...175,520,467
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1, CNS ISO RGD PMID:16931638 RGD:5133416 NCBI chr19:8,641,369...8,660,970
Ensembl chr19:8,641,153...8,660,951
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2, cardiac ISO DNA:SNP: :rs6962027 (human) RGD PMID:19308904 RGD:5509586 NCBI chr 6:36,364,928...36,505,573
Ensembl chr 6:36,365,019...36,505,349
JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3, cardiac severity ISO
IMP
RGD PMID:20394512 PMID:18348887 RGD:5133437, RGD:5133438 NCBI chr13:9,925,522...10,411,131
Ensembl chr13:9,925,522...10,410,883
JBrowse link
G Chuk conserved helix-loop-helix ubiquitous kinase IMP RGD PMID:21496385 RGD:5133703 NCBI chr19:44,061,773...44,095,940
Ensembl chr19:44,061,774...44,095,919
JBrowse link
G Clca1 chloride channel accessory 1 susceptibility IMP
ISO
DNA:SNPs (human) RGD PMID:11296262 PMID:17898169 PMID:15318163 RGD:4145661, RGD:4145653, RGD:4145656 NCBI chr 3:144,710,298...144,738,537
Ensembl chr 3:144,709,578...144,738,537
JBrowse link
G Cldn18 claudin 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27215490 NCBI chr 9:99,572,849...99,599,320
Ensembl chr 9:99,571,514...99,599,320
JBrowse link
G Cma1 chymase 1, mast cell severity
susceptibility
no_association
ISO protein:increased expression:lung epithelium, mast cell (human)
DNA:duplications:3' utr:g.*254-?dupTG, dupGA (human)
DNA:polymorphism:5' utr:g.-1903G>A rs1800875 (human)
RGD PMID:20813890 PMID:15924217 PMID:15248847 RGD:5128804, RGD:1625396, RGD:1625397 NCBI chr14:56,178,908...56,182,132
Ensembl chr14:56,178,908...56,182,132
JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 ISO DNA:SNP: :RS242941 (human)
DNA:SNPs: :rs1876828, rs242939, rs242941 (human)
RGD PMID:19663668 PMID:16113459 RGD:5147485, RGD:5147488 NCBI chr11:104,021,289...104,066,349
Ensembl chr11:104,023,681...104,066,349
JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 ISO DNA:SNPs: :multiple (human) RGD PMID:18408560 RGD:5130938 NCBI chr 6:55,067,033...55,110,001
Ensembl chr 6:55,067,034...55,110,001
JBrowse link
G Crp C-reactive protein, pentraxin-related ISO protein:increased expression:serum RGD PMID:21140796 RGD:5131288 NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598
JBrowse link
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) severity IEP
IMP
ISO
protein:increased expression:lung
protein:increased expression:sputum
RGD PMID:20405019 PMID:9717963 PMID:19213775 RGD:5131473, RGD:10449521, RGD:5131476 NCBI chr11:54,138,096...54,140,725
Ensembl chr11:54,138,097...54,140,493
JBrowse link
G Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) ISO RGD PMID:17145927 RGD:1601020 NCBI chr15:78,210,000...78,235,201
Ensembl chr15:78,209,952...78,238,047
JBrowse link
G Csf2rb2 colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage) ISO RGD PMID:17145927 RGD:1601020 NCBI chr15:78,166,707...78,189,921
Ensembl chr15:78,166,707...78,189,921
JBrowse link
G Csf3 colony stimulating factor 3 (granulocyte) IEP
ISO
protein:increased expression:lung RGD PMID:20405019 PMID:21396376 RGD:5131473, RGD:5133731 NCBI chr11:98,591,287...98,594,457
Ensembl chr11:98,592,089...98,594,455
JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 severity
treatment
no_association
ISO
IDA
IMP
IEP
protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
DNA:SNPs: :multiple (human)
DNA:SNP: :rs3087243 (human)
DNA:polymorphism:promoter:-318C>T (human)
DNA:SNPs:promoter, exon:-1147C>T, -318C>T, 49A>G (human)
DNA:polymorphisms:promoter, exon:-318C>T 49A>G (human)
CTD
RGD
PMID:28807506 PMID:15871446 PMID:11726402 PMID:15316504 PMID:19895365 More... RGD:4891529, RGD:11344922, RGD:4891519, RGD:4891526, RGD:4891510, RGD:4891521, RGD:4891522, RGD:4891514, RGD:4891528, RGD:4891517, RGD:4891516, RGD:4891527 NCBI chr 1:60,948,184...60,954,991
Ensembl chr 1:60,926,159...60,954,991
JBrowse link
G Ctnna3 catenin (cadherin associated protein), alpha 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19187332 NCBI chr10:63,265,877...64,841,174
Ensembl chr10:63,265,877...64,839,446
JBrowse link
G Cx3cl1 chemokine (C-X3-C motif) ligand 1 ISO protein:increased expression:plasma RGD PMID:14657873 RGD:4891906 NCBI chr 8:95,498,808...95,509,055
Ensembl chr 8:95,498,637...95,509,055
JBrowse link
G Cx3cr1 chemokine (C-X3-C motif) receptor 1 no_association IMP
ISO
DNA:SNPs: :p.V249I, rs2669849 (human)
DNA:polymorphisms: :p.V249I, p.T280M (human)
RGD PMID:21037587 PMID:17082760 PMID:17505143 RGD:4891882, RGD:4891895, RGD:4891904 NCBI chr 9:119,877,749...119,897,362
Ensembl chr 9:119,730,682...119,898,945
JBrowse link
G Cxcl1 chemokine (C-X-C motif) ligand 1 severity ISO RGD PMID:20371397 RGD:5134983 NCBI chr 5:91,039,104...91,040,980
Ensembl chr 5:91,039,100...91,040,974
JBrowse link
G Cxcl10 chemokine (C-X-C motif) ligand 10 ISO
IMP
protein:decreased expression:plasma RGD PMID:17302903 PMID:16602032 PMID:11994485 RGD:5135439, RGD:5135457, RGD:5135452 NCBI chr 5:92,494,497...92,496,748
Ensembl chr 5:92,494,497...92,496,748
JBrowse link
G Cxcl14 chemokine (C-X-C motif) ligand 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21150878 NCBI chr13:56,436,456...56,444,624
Ensembl chr13:56,436,456...56,444,364
JBrowse link
G Cxcl2 chemokine (C-X-C motif) ligand 2 IEP mRNA:increased expression:lung RGD PMID:20045013 RGD:5129686 NCBI chr 5:91,051,758...91,053,797
Ensembl chr 5:91,051,730...91,053,797
JBrowse link
G Cxcl3 chemokine (C-X-C motif) ligand 3 severity ISO RGD PMID:20371397 RGD:5134983 NCBI chr 5:90,933,960...90,935,952
Ensembl chr 5:90,933,962...90,937,459
JBrowse link
G Cxcl5 chemokine (C-X-C motif) ligand 5 ISO
IEP
mRNA:increased expression:bronchus epithelium RGD PMID:17234659 PMID:9620668 RGD:5135243, RGD:5135265 NCBI chr 5:90,907,157...90,909,484
Ensembl chr 5:90,907,219...90,909,483
JBrowse link
G Cxcl9 chemokine (C-X-C motif) ligand 9 IMP RGD PMID:15210824 RGD:5135447 NCBI chr 5:92,469,190...92,475,938
Ensembl chr 5:92,469,206...92,475,938
JBrowse link
G Cxcr3 chemokine (C-X-C motif) receptor 3 susceptibility
severity
IEP
ISO
DNA:SNP:intron:IVS1+234G>A (human)
protein:decreased expression:respiratory system fluid/secretion, T cell
RGD PMID:18094012 PMID:16043121 PMID:16548899 PMID:17641057 RGD:4892088, RGD:5143934, RGD:5143932, RGD:5135484 NCBI chr  X:100,775,141...100,777,753
Ensembl chr  X:100,775,141...100,777,875
JBrowse link
G Cyba cytochrome b-245, alpha polypeptide susceptibility ISO DNA:polymorphism: :-930A>G (human)
DNA:SNPs: :-930A>G, 242C>T, 640A>G (human)
RGD PMID:19459419 PMID:18716406 RGD:4311041, RGD:4772770 NCBI chr 8:123,151,510...123,159,679
Ensembl chr 8:123,151,515...123,159,669
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 IEP mRNA, protein:increased expression, decreased activity:lung RGD PMID:12415424 RGD:4892074 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 ISO DNA:polymorphism: :1934G>A (human) RGD PMID:19575027 RGD:5143944 NCBI chr15:82,254,728...82,264,461
Ensembl chr15:82,254,728...82,264,461
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 ISO
IEP
mRNA:decreased expression:leukocyte
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:28807506 PMID:20514434 PMID:17081494 RGD:4892076, RGD:4892220 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900
JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 no_association
severity
ISO
IMP
DNA:SNPs:promoter, exon:multiple (human)
DNA:SNPs:promoter:-634C>T, -475A>C, -336A>G (human)
DNA:SNP: :927T>C (human)
mRNA, protein:increased expression:respiratory system mucosa
RGD PMID:16771777 PMID:16630147 PMID:16776674 PMID:8087328 PMID:11591188 More... RGD:4889116, RGD:4784257, RGD:4782072, RGD:4888514, RGD:4848936, RGD:4781742, RGD:4781449, RGD:4843543, RGD:4847129 NCBI chr  X:105,617,952...105,647,329
Ensembl chr  X:105,617,952...105,647,285
JBrowse link
G Cysltr2 cysteinyl leukotriene receptor 2 ISO DNA:polymorphism: :601A>G (human)
DNA:polymorphism: :-1220A>C (human)
RGD PMID:15475736 PMID:15454733 RGD:5144002, RGD:5144003 NCBI chr14:73,263,515...73,286,554
Ensembl chr14:73,263,043...73,286,554
JBrowse link
G Dcn decorin ISO RGD PMID:16387756 RGD:2311423 NCBI chr10:97,315,362...97,354,025
Ensembl chr10:97,315,471...97,354,005
JBrowse link
G Defb1 defensin beta 1 susceptibility ISO DNA:SNP: :-1816 T>C (human)
DNA:SNPs:5' utr:g.-52G>A, g.-44C>G, g.-20G>A (human)
RGD PMID:15696078 PMID:16435024 RGD:4892263, RGD:4892254 NCBI chr 8:22,266,571...22,285,201
Ensembl chr 8:22,266,615...22,285,201
JBrowse link
G Dnah5 dynein, axonemal, heavy chain 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chr15:28,155,000...28,472,191
Ensembl chr15:28,203,898...28,472,198
JBrowse link
G Dnmt1 DNA methyltransferase (cytosine-5) 1 IEP
ISO
DNA,mRNA:hypermethylation,decreased expression:promoter,respiratory tract:
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:23423710 PMID:23196709 RGD:9588646 NCBI chr 9:20,818,501...20,871,184
Ensembl chr 9:20,818,505...20,871,184
JBrowse link
G Dpp10 dipeptidylpeptidase 10 ISO DNA:SNPs (human)
DNA:SNP:exon (human)
protein:increased expression:bronchus
DNA:SNP: :rs10208402 (human)
RGD
GAD
PMID:21103062 PMID:15118671 PMID:14566338 PMID:17967935 PMID:19672052 RGD:4889866, RGD:1331525, RGD:4892276, RGD:4892278, RGD:4892275 NCBI chr 1:123,259,867...124,773,809
Ensembl chr 1:123,249,200...124,773,776
JBrowse link
G Ear1 eosinophil-associated, ribonuclease A family, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8874658 PMID:12153692 PMID:12587966 NCBI chr14:44,056,222...44,057,096
Ensembl chr14:44,056,222...44,112,974
JBrowse link
G Ebi3 Epstein-Barr virus induced gene 3 IMP RGD PMID:21255010 RGD:5128488 NCBI chr17:56,259,623...56,264,022
Ensembl chr17:56,259,640...56,264,022
JBrowse link
G Edn1 endothelin 1 ISO DNA:transition:intron:g.4124T>C (human)
CTD Direct Evidence: marker/mechanism
Severe Persistent Allergic Asthma; protein:increased secretion:lung (human)
CTD
RGD
PMID:16981460 PMID:11668616 PMID:20588001 RGD:4144869, RGD:4144895 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466
JBrowse link
G Ednra endothelin receptor type A IMP RGD PMID:18632188 PMID:17448648 RGD:4892288, RGD:4892322 NCBI chr 8:78,389,658...78,451,081
Ensembl chr 8:78,389,660...78,451,093
JBrowse link
G Ednrb endothelin receptor type B IMP
ISO
DNA:polymorphism (human)
mRNA:increased expression:bronchus, smooth muscle cell
RGD PMID:18632188 PMID:17470272 PMID:15245576 RGD:4892288, RGD:4892321, RGD:4892324 NCBI chr14:104,052,051...104,083,248
Ensembl chr14:104,052,061...104,081,838
JBrowse link
G Egfr epidermal growth factor receptor severity IMP
ISO
IEP
protein:increased expression:bronchial epithelium (human)
protein:increased expression:lung epithelium (mouse)
protein:increased expression:lung epithelium (rat)
RGD PMID:21224214 PMID:12580917 PMID:21072743 PMID:19954006 RGD:5131633, RGD:5131468, RGD:5131642, RGD:5131870 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158
JBrowse link
G Egr1 early growth response 1 IMP
ISO
mRNA:increased expression:bronchoalveolar lavage cell (human)
DNA:snp:5' utr:g.-4071A>G rs7729723 (human)
RGD PMID:11254538 PMID:18774390 PMID:18507785 RGD:5131985, RGD:5130915, RGD:5131993 NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037
JBrowse link
G Elp1 elongator complex protein 1 no_association ISO RGD PMID:11281413 PMID:12774215 RGD:5129157, RGD:5129158 NCBI chr 4:56,746,547...56,802,565
Ensembl chr 4:56,749,680...56,802,331
JBrowse link
G Ephx1 epoxide hydrolase 1, microsomal susceptibility ISO DNA:SNPs:exons:p.Y113H (rs1051740), p.H139R (rs2234922) (human) RGD PMID:17711870 RGD:4889407 NCBI chr 1:180,817,121...180,845,134
Ensembl chr 1:180,803,775...180,848,469
JBrowse link
G Epx eosinophil peroxidase severity
disease_progression
ISO protein:increased activity:sputum,nasal,pharyngeal mucosa RGD PMID:26645423 PMID:12199967 PMID:20813885 RGD:11574908, RGD:13506892, RGD:13506891 NCBI chr11:87,754,824...87,766,362
Ensembl chr11:87,754,826...87,766,362
JBrowse link
G Esr2 estrogen receptor 2 (beta) ISO mRNA:decreased expression:lung (rat) RGD PMID:18375789 RGD:8694127 NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033
JBrowse link
G F2 coagulation factor II ISO protein:increased expression:plasma
associated with Rhinosinusitis, associated with Nasal Polyps;protein:increased expression:nasal mucus
RGD PMID:21658190 PMID:21711961 RGD:5147753, RGD:5147783 NCBI chr 2:91,442,742...91,466,802
Ensembl chr 2:91,455,665...91,466,759
JBrowse link
G F2rl1 coagulation factor II (thrombin) receptor-like 1 ISO RGD PMID:19864598 RGD:4892589 NCBI chr13:95,648,226...95,661,748
Ensembl chr13:95,648,240...95,661,735
JBrowse link
G F7 coagulation factor VII treatment ISO RGD PMID:24523826 RGD:11040539 NCBI chr 8:13,075,499...13,085,809
Ensembl chr 8:13,076,034...13,085,809
JBrowse link
G Fas Fas (TNF receptor superfamily member 6) ISO mRNA:increased expression:eosinophil RGD PMID:16337971 RGD:1600350 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
JBrowse link
G Fcer1a Fc receptor, IgE, high affinity I, alpha polypeptide severity ISO Asthma symptoms persistent despite steroids in humans
Fatal asthma subjects
RGD PMID:20937062 PMID:21388666 RGD:5128717, RGD:5128711 NCBI chr 1:173,048,836...173,054,799
Ensembl chr 1:173,048,851...173,054,781
JBrowse link
G Fcgr2b Fc receptor, IgG, low affinity IIb IMP RGD PMID:20179765 RGD:11344929 NCBI chr 1:170,788,127...170,803,691
Ensembl chr 1:170,786,186...170,804,116
JBrowse link
G Fcgr4 Fc receptor, IgG, low affinity IV susceptibility ISO DNA:polymorphism:exon:p.F158V(rs396991)(human) RGD PMID:18199088 RGD:5508449 NCBI chr 1:170,846,495...170,857,330
Ensembl chr 1:170,846,489...170,857,330
JBrowse link
G Fga fibrinogen alpha chain treatment ISO RGD PMID:24523826 RGD:11040539 NCBI chr 3:82,933,460...82,940,934
Ensembl chr 3:82,933,383...82,940,934
JBrowse link
G Fkbp5 FK506 binding protein 5 ISO ClinVar Annotator: match by term: Asthma ClinVar NCBI chr17:28,617,727...28,705,123
Ensembl chr17:28,618,068...28,736,501
JBrowse link
G Foxp3 forkhead box P3 treatment ISO
IDA
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:27965764 PMID:29317916 PMID:28944907 PMID:27633092 RGD:38549365, RGD:38548920 NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484
JBrowse link
G Gata3 GATA binding protein 3 ISO RGD PMID:9949310 PMID:18186587 RGD:5128802, RGD:5128803 NCBI chr 2:9,861,889...9,892,762
Ensembl chr 2:9,861,889...9,894,845
JBrowse link
G Gc vitamin D binding protein IMP
ISO
protein, mRNA:increased expression:bronchoalveolar lavage fluid: RGD PMID:21169467 PMID:21169467 RGD:5509920, RGD:5509920 NCBI chr 5:89,565,370...89,605,757
Ensembl chr 5:89,565,381...89,605,757
JBrowse link
G Gsta1 glutathione S-transferase, alpha 1 (Ya) susceptibility ISO DNA:polymorphism:promoter: -69C>T (human) RGD PMID:20374258 RGD:5490988 NCBI chr 9:78,137,951...78,149,965
Ensembl chr 9:78,137,938...78,149,966
JBrowse link
G Gstm1 glutathione S-transferase, mu 1 resistance
susceptibility
ISO DNA:deletion: :
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:16870661 PMID:18988661 PMID:17651144 PMID:21051083 PMID:11075422 RGD:4142509, RGD:5490962, RGD:4140921 NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289
JBrowse link
G Gstm3 glutathione S-transferase, mu 3 ISO DNA:polymorphism RGD PMID:11470996 PMID:17550934 RGD:5135039, RGD:5135038 NCBI chr 3:107,871,012...107,876,490
Ensembl chr 3:107,871,012...107,876,599
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 ISO DNA:polymorphism RGD PMID:11470996 PMID:17550934 RGD:5135038 RGD:5135039 NCBI chr 3:107,803,170...107,806,001
Ensembl chr 3:107,803,137...107,806,002
JBrowse link
G Gsto2 glutathione S-transferase omega 2 susceptibility ISO DNA:polymorphism:exon:p. N142D (human) RGD PMID:20374258 RGD:5490988 NCBI chr19:47,853,879...47,874,747
Ensembl chr19:47,853,973...47,874,763
JBrowse link
G Gstp1 glutathione S-transferase, pi 1 severity
susceptibility
disease_progression
no_association
ISO
IAGP
DNA:polymorphism:exon:p.I105V (rs1695) (human)
CTD Direct Evidence: marker/mechanism
DNA:SNPs:exons:p.I105V (rs1695), A114V (rs1138272) (human)
DNA:SNPs:intron,exon:(rs749174), (rs1138272)(human)
DNA:SNPs: :p.I105V, p.A114V (human)
DNA:polymorphism:exon:p.I105V (human)
DNA:SNP: :p.A114V (human)
CTD
RGD
PMID:11994713 PMID:16870661 PMID:18988661 PMID:24117884 PMID:29411558 More... RGD:4142526, RGD:5490999, RGD:5490991, RGD:5490985, RGD:4140951, RGD:4142519, RGD:4140947, RGD:4140946 NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985
JBrowse link
G Gstt1 glutathione S-transferase, theta 1 susceptibility ISO DNA:deletion: : RGD PMID:15300848 PMID:21051083 PMID:11075422 RGD:4142539, RGD:5490962, RGD:4140921 NCBI chr10:75,619,647...75,634,418
Ensembl chr10:75,619,647...75,634,418
JBrowse link
G H2-Aa histocompatibility 2, class II antigen A, alpha ISO DNA:polymorphisms (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphism (human)
CTD
RGD
PMID:10792356 PMID:12890388 PMID:10051703 PMID:11802952 PMID:19052351 RGD:5147799, RGD:1331670, RGD:5147831, RGD:5147617 NCBI chr17:34,501,718...34,506,797
Ensembl chr17:34,501,718...34,506,797
JBrowse link
G H2-Ab1 histocompatibility 2, class II antigen A, beta 1 susceptibility
disease_progression
no_association
ISO Alternaria sensitive asthma
DNA:polymorphisms: :
CTD Direct Evidence: marker/mechanism
DNA:polymorphisms (human)
CTD
RGD
PMID:10792356 PMID:20298583 PMID:20159242 PMID:20214848 PMID:23331206 More... RGD:4144113, RGD:13506913, RGD:4144181, RGD:13506906, RGD:5147831, RGD:5147799, RGD:5147617 NCBI chr17:34,482,201...34,488,392
Ensembl chr17:34,476,663...34,488,393
JBrowse link
G H2-Ea histocompatibility 2, class II antigen E alpha susceptibility ISO DNA:polymorphisms: : RGD PMID:20159242 RGD:13506913 NCBI chr17:34,560,926...34,563,619
Ensembl chr17:34,560,933...34,563,619
JBrowse link
G H2-Eb1 histocompatibility 2, class II antigen E beta susceptibility
no_association
severity
ISO DNA:polymorphisms: :
CTD Direct Evidence: marker/mechanism
DNA:polymorphism (human)
CTD
RGD
PMID:16792590 PMID:19528258 PMID:20159242 PMID:23331206 PMID:10051703 More... RGD:4144196, RGD:13506913, RGD:13506906, RGD:1331670, RGD:5147663, RGD:5147607, RGD:4144181 NCBI chr17:34,524,841...34,535,648
Ensembl chr17:34,524,841...34,535,648
JBrowse link
G H2-M2 histocompatibility 2, M region locus 2 susceptibility ISO DNA:polymorphism: RGD PMID:28380482 RGD:13506910 NCBI chr17:37,791,742...37,794,445
Ensembl chr17:37,791,742...37,794,443
JBrowse link
G H2-M3 histocompatibility 2, M region locus 3 susceptibility ISO CTD Direct Evidence: marker/mechanism CTD
OMIM
RGD
PMID:15611928 RGD:5144118 NCBI chr17:37,581,094...37,585,376
Ensembl chr17:37,581,111...37,585,375
JBrowse link
G H2-Pa histocompatibility 2, P region alpha locus susceptibility ISO DNA:polymorphism: : RGD PMID:21814517 RGD:13506911 NCBI chr17:34,303,587...34,304,826
Ensembl chr17:34,303,575...34,304,797
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 ISO RGD PMID:20628202 RGD:5128851 NCBI chr11:46,630,644...46,670,405
Ensembl chr11:46,625,907...46,670,405
JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 IMP RGD PMID:17517968 RGD:5135525 NCBI chr11:46,345,758...46,372,082
Ensembl chr11:46,345,762...46,372,082
JBrowse link
G Hc hemolytic complement severity IEP
ISO
IAGP
mRNA:decreased expression:lung RGD PMID:10973279 PMID:15278436 PMID:20143644 PMID:11591795 PMID:20802484 RGD:5130158, RGD:5129512, RGD:5129706, RGD:1600651, RGD:5129681 NCBI chr 2:34,873,341...34,958,518
Ensembl chr 2:34,873,343...34,951,450
JBrowse link
G Hdac2 histone deacetylase 2 ISO mRNA:decreased expression:macrophage: RGD PMID:20538962 RGD:9590321 NCBI chr10:36,850,293...36,877,885
Ensembl chr10:36,850,540...36,877,885
JBrowse link
G Hdc histidine decarboxylase ISO associated with Rhinitis;DNA:SNP: :p.E644D (rs2073440) (human) RGD PMID:20608921 RGD:5128884 NCBI chr 2:126,435,579...126,465,942
Ensembl chr 2:126,435,587...126,461,219
JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit treatment IEP RGD PMID:18160846 RGD:10402541 NCBI chr12:73,948,098...73,994,328
Ensembl chr12:73,948,149...73,994,304
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase ISO RGD PMID:20084838 RGD:5508450 NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444
JBrowse link
G Hmox1 heme oxygenase 1 severity IDA
ISO
CTD Direct Evidence: marker/mechanism
mRNA;protein:increased expression:Leukocytes, Mononuclear
CTD
RGD
PMID:18048809 PMID:20596599 PMID:16196283 RGD:4145403, RGD:4145408 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Hnmt histamine N-methyltransferase no_association
susceptibility
ISO ClinVar Annotator: match by term: Asthma, susceptibility to
CTD Direct Evidence: marker/mechanism
ClinVar
OMIM
CTD
RGD
PMID:10752634 PMID:10803682 PMID:16205835 PMID:17651147 PMID:15693910 More... RGD:5128888, RGD:5128883, RGD:5128885, RGD:5128881, RGD:5128887 NCBI chr 2:23,892,923...23,939,756
Ensembl chr 2:23,892,922...23,939,406
JBrowse link
G Hp haptoglobin ISO RGD PMID:21471098 PMID:21169467 RGD:5144151, RGD:5509920 NCBI chr 8:110,301,760...110,305,804
Ensembl chr 8:110,301,760...110,305,804
JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11932298 NCBI chr 8:106,245,378...106,250,620
Ensembl chr 8:106,245,387...106,250,620
JBrowse link
G Htr2a 5-hydroxytryptamine (serotonin) receptor 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:25322896 NCBI chr14:74,878,314...74,944,299
Ensembl chr14:74,878,280...74,946,934
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO
IEP
protein:increased expression:lung, serum (rat)
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:aorta (mouse)
protein:increased secretion:lung (human)
CTD
RGD
PMID:17014439 PMID:25003170 PMID:20953388 PMID:20400685 PMID:20205697 RGD:4145331, RGD:4145444, RGD:4145509 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
JBrowse link
G Ifng interferon gamma treatment
resistance
IDA
IMP
ISO
protein:increased expression:sputum RGD
GAD
PMID:19542437 PMID:12396623 PMID:15118671 PMID:20953328 PMID:20817868 RGD:5128479, RGD:10755706, RGD:1331525, RGD:4145525, RGD:4145651 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Ifngr1 interferon gamma receptor 1 IAGP
ISO
DNA: SNP: Leu467Pro RGD PMID:21737883 PMID:12851715 RGD:6480255, RGD:6480431 NCBI chr10:19,467,697...19,485,977
Ensembl chr10:19,467,697...19,485,977
JBrowse link
G Ifnl2 interferon lambda 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22295096 NCBI chr 7:28,208,209...28,209,957
Ensembl chr 7:28,208,261...28,209,880
JBrowse link
G Ikzf3 IKAROS family zinc finger 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25256354 NCBI chr11:98,355,436...98,437,157
Ensembl chr11:98,355,728...98,436,857
JBrowse link
G Il10 interleukin 10 treatment
susceptibility
ISO
IMP
IEP
CTD Direct Evidence: marker/mechanism
DNA:polymorphism: :-627C>A (human)
protein:decreased expression:plasma
CTD
RGD
PMID:29317916 PMID:20560982 PMID:21998459 PMID:20237464 PMID:20644177 More... RGD:5131623, RGD:11046261, RGD:4140471, RGD:4140459, RGD:4143221, RGD:4140451, RGD:4140421 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Il12a interleukin 12a IMP RGD PMID:17056578 PMID:17548618 RGD:4438438, RGD:4373570 NCBI chr 3:68,597,977...68,605,883
Ensembl chr 3:68,597,977...68,605,880
JBrowse link
G Il12b interleukin 12b severity
susceptibility
ISO DNA:polymorphisms:introns:
DNA:polymorphisms:promoter, 3'utr:
DNA:polymorphism:promoter
RGD PMID:15322986 PMID:16210052 PMID:12241719 RGD:1600043, RGD:4145438, RGD:4145428 NCBI chr11:44,290,890...44,305,504
Ensembl chr11:44,290,890...44,304,860
JBrowse link
G Il13 interleukin 13 susceptibility
severity
no_association
IMP
ISO
IDA
IEP
ClinVar Annotator: match by term: Asthma, susceptibility to
CTD Direct Evidence: marker/mechanism
associated with Dermatitis, Atopic;DNA, protein:SNP, increased expression:promoter, serum:-1112C>T (human)
DNA:polymorphism: :-1512A>C, -1112C>T, 2044G>A (human)
mRNA, protein:increased expression:esophagus, Bronchoalveolar Lavage Fluid
protein:increased expression:serum
DNA:polymorphism:cds:p.R130Q (human)
DNA:polymorphisms:promoters,exon4: rs1881457, rs1800925, rs20541 (human)
DNA:polymorphism: :p. R110Q (human)
DNA:SNP: :c. -646A>G (human)
protein:increased expression:sputum
DNA:polymorphism: :c. 1923C>T (human)
DNA:polymorphism:promoter:c. -1055C>T (human)
DNA:polymorphisms: :rs20541, rs1295685(human)
DNA:polymorphism:3'utr:c.4738G>A (human)
DNA:polymorphism: :c.-1055C>T (human)
DNA:polymorphism: :c. 2044G>A (human)
ClinVar
OMIM
CTD
RGD
PMID:10699178 PMID:11588017 PMID:11709756 PMID:12847555 PMID:12928861 More... RGD:4206706, RGD:8549509, RGD:4892639, RGD:2301686, RGD:4145664, RGD:4145453, RGD:4145508, RGD:2307110, RGD:4763153, RGD:4763761, RGD:4145601, RGD:4145639, RGD:4321828, RGD:4146241, RGD:4145777, RGD:4145775, RGD:4220633, RGD:4145534, RGD:4765128, RGD:4145593, RGD:4145776 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529
JBrowse link
G Il13ra1 interleukin 13 receptor, alpha 1 no_association IDA
ISO
IMP
IEP
DNA:polymorphism: :1398A>G (human)
DNA:polymorphisms:promoter, 3' utr:-281T>G, 1365A>G (human)
DNA:polymorphism: :1050C>T (human)
mRNA:increased expression:bronchus
RGD PMID:11714828 PMID:17006604 PMID:17392323 PMID:10686479 PMID:18480254 More... RGD:4892654, RGD:4892639, RGD:4892650, RGD:4892655, RGD:4892647, RGD:4892646 NCBI chr  X:35,375,761...35,434,915
Ensembl chr  X:35,375,763...35,434,912
JBrowse link
G Il13ra2 interleukin 13 receptor, alpha 2 IMP
ISO
IEP
protein:increased expression:serum
mRNA:increased expression:bronchus
RGD PMID:17885690 PMID:21462799 PMID:20383033 RGD:4892649, RGD:8549521, RGD:4892646 NCBI chr  X:146,166,474...146,214,982
Ensembl chr  X:146,166,472...146,212,188
JBrowse link
G Il15 interleukin 15 no_association IMP
ISO
DNA:SNPs: :multiple (human) RGD PMID:15843549 PMID:16629787 PMID:11160248 PMID:15131572 PMID:19133918 RGD:5000757, RGD:4984421, RGD:4990462, RGD:5000758, RGD:5000760 NCBI chr 8:83,058,253...83,129,883
Ensembl chr 8:83,058,261...83,129,851
JBrowse link
G Il16 interleukin 16 no_association
severity
IMP
ISO
DNA:SNP:promoter:-295T>C (human)
protein:increased expression:serum
associated with Rhinitis;protein:increased expression:respiratory system fluid/secretion
RGD PMID:10585533 PMID:15784111 PMID:16387589 PMID:12872394 PMID:16734115 RGD:5024937, RGD:5024935, RGD:5024934, RGD:5024930, RGD:5024928 NCBI chr 7:83,292,027...83,395,479
Ensembl chr 7:83,292,033...83,394,934
JBrowse link
G Il17a interleukin 17A susceptibility ISO
IMP
mRNA,protein:increased expression:Leukocytes, Mononuclear, lung, serum
protein:increased expression:sputum
protein:increased expression:alveolar macrophage
DNA:SNP:promoter:rs2275913 (human)
RGD PMID:18060619 PMID:20351038 PMID:15730730 PMID:18941201 PMID:20437253 RGD:4839043, RGD:4888527, RGD:4889114, RGD:4889152, RGD:4889139 NCBI chr 1:20,801,129...20,804,720
Ensembl chr 1:20,801,129...20,804,720
JBrowse link
G Il17rb interleukin 17 receptor B IMP associated with Picornaviridae Infections RGD PMID:25273095 RGD:39128256 NCBI chr14:29,718,125...29,730,853
Ensembl chr14:29,718,092...29,730,853
JBrowse link
G Il18 interleukin 18 severity
susceptibility
disease_progression
ISO
IMP
DNA:SNPs:Promoter:c. -607C>A (rs1946518), -137G/C (rs187238) (human)
DNA:SNP:promoter:c.and -137G>C (rs187238)(human)
protein:increased expression:serum
DNA:SNP:promoter: c.-380C>G (rs5744247)(human)
DNA:polymorphism: :c. -105A>C (human)
RGD PMID:17767553 PMID:20497957 PMID:16433859 PMID:18826499 PMID:11174201 More... RGD:4889585, RGD:4889898, RGD:4889923, RGD:4889908, RGD:4889863, RGD:4889898, RGD:4889900, RGD:4889910 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140
JBrowse link
G Il18r1 interleukin 18 receptor 1 ISO
IEP
DNA:SNP: :rs3771166 (human)
DNA:SNPs: :multiple (human)
RGD PMID:19910030 PMID:20860503 PMID:18382474 PMID:11972614 PMID:18774397 RGD:5024945, RGD:5024942, RGD:5024947, RGD:5024948, RGD:5024946 NCBI chr 1:40,504,712...40,540,014
Ensembl chr 1:40,504,712...40,540,014
JBrowse link
G Il19 interleukin 19 IEP mRNA, protein:increased expression:lung, serum RGD PMID:15557163 RGD:5037236 NCBI chr 1:130,860,393...130,873,194
Ensembl chr 1:130,860,393...130,867,852
JBrowse link
G Il1a interleukin 1 alpha ISO DNA:polymorphisms: : RGD PMID:18763028 RGD:4142802 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
JBrowse link
G Il1b interleukin 1 beta susceptibility IDA
ISO
CTD Direct Evidence: marker/mechanism
protein:decreased expression:neutrophil
DNA:polymorphism: :-511C>T (human)
CTD
RGD
PMID:9176529 PMID:19684087 PMID:19842845 PMID:18926055 RGD:4142836, RGD:4142830, RGD:4142864 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 susceptibility
severity
IEP
ISO
IMP
protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs1420101 (human)
DNA:SNPs:intron:rs1420089, rs1861245,rs1946131 (human)
DNA:SNP: :rs10197862 (human)
DNA:SNP: :rs1041973 (human)
CTD
RGD
PMID:19198610 PMID:21150878 PMID:21804549 PMID:24241537 PMID:27472835 More... RGD:5144235, RGD:5144245, RGD:5144244, RGD:5144243, RGD:5144242, RGD:5144240, RGD:5144239, RGD:5144237 NCBI chr 1:40,444,025...40,504,578
Ensembl chr 1:40,468,730...40,504,575
JBrowse link
G Il1rn interleukin 1 receptor antagonist susceptibility
severity
ISO DNA:SNP: :rs2234678 (human)
CTD Direct Evidence: marker/mechanism
DNA:SNPs: :multiple (human)
DNA:SNPs: :rs447713, rs3087271 (human)
protein:increased expression:plasma
DNA, protein:repeat, decreased expression (human)
DNA:polymorphism:intron (human)
CTD
RGD
PMID:9176529 PMID:17107994 PMID:15020290 PMID:16409203 PMID:16724092 More... RGD:4143208, RGD:4143216, RGD:4143163, RGD:4143209, RGD:4143225, RGD:4143224, RGD:4142864, RGD:4142802 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506
JBrowse link
G Il2 interleukin 2 susceptibility ISO DNA:SNP:promoter:rs2069762(human) RGD PMID:20926789 PMID:16333313 RGD:4889118, RGD:8663473 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
JBrowse link
G Il21 interleukin 21 ISO DNA:SNP:exon:5250C>T (human) RGD PMID:18802358 RGD:5147396 NCBI chr 3:37,276,908...37,286,785
Ensembl chr 3:37,276,908...37,286,785
JBrowse link
G Il22 interleukin 22 treatment
severity
IMP
ISO
mRNA:increased expression:blood, mononuclear cell
protein:increased expression:serum
RGD PMID:21789181 PMID:21998459 PMID:21535180 PMID:21297073 RGD:5147401, RGD:11046261, RGD:5147409, RGD:5147403 NCBI chr10:118,040,456...118,045,952
Ensembl chr10:118,040,847...118,045,952
JBrowse link
G Il22b interleukin 22B severity ISO protein:increased expression:serum
mRNA:increased expression:blood, mononuclear cell
RGD PMID:21297073 PMID:21535180 RGD:5147403 RGD:5147409 NCBI chr10:118,125,534...118,130,943
Ensembl chr10:118,125,534...118,130,943
JBrowse link
G Il23r interleukin 23 receptor IMP RGD PMID:19935773 RGD:5037240 NCBI chr 6:67,399,916...67,468,839
Ensembl chr 6:67,399,916...67,468,839
JBrowse link
G Il25 interleukin 25 IEP mRNA, protein:increased expression:lung RGD PMID:25273095 RGD:39128256 NCBI chr14:55,170,152...55,173,294
Ensembl chr14:55,170,152...55,173,294
JBrowse link
G Il27 interleukin 27 treatment
susceptibility
IDA
IMP
ISO
protein:increased expression:sputum
DNA:SNP: :g.-964A>G (human)
RGD PMID:17878337 PMID:26595888 PMID:20817868 PMID:17318299 PMID:19542437 RGD:5128491, RGD:11076728, RGD:4145651, RGD:5128485, RGD:5128479 NCBI chr 7:126,188,181...126,194,197
Ensembl chr 7:126,188,182...126,194,113
JBrowse link
G Il27ra interleukin 27 receptor, alpha IMP RGD PMID:16081811 RGD:5128496 NCBI chr 8:84,756,915...84,769,250
Ensembl chr 8:84,756,923...84,769,218
JBrowse link
G Il2ra interleukin 2 receptor, alpha chain IMP RGD PMID:21377197 PMID:20525707 RGD:5147437, RGD:5147445 NCBI chr 2:11,647,603...11,698,005
Ensembl chr 2:11,647,618...11,698,004
JBrowse link
G Il2rb interleukin 2 receptor, beta chain ISO
IMP
DNA:SNP: :rs2284033 (human) RGD PMID:20860503 PMID:18641329 RGD:5024942, RGD:5147447 NCBI chr15:78,363,456...78,396,569
Ensembl chr15:78,363,456...78,379,471
JBrowse link
G Il3 interleukin 3 susceptibility ISO DNA:SNP: :rs40401(human)
DNA:polymorphism:cds:+79T>C(S27P)(human)
RGD PMID:24684517 PMID:15372320 RGD:13506914, RGD:13506916 NCBI chr11:54,155,911...54,158,105
Ensembl chr11:54,156,129...54,158,103
JBrowse link
G Il33 interleukin 33 treatment
severity
ISO
IMP
CTD Direct Evidence: marker/mechanism
associated with viral pneumonia;
associated with fungal infectious disease
CTD
RGD
PMID:19198610 PMID:21804549 PMID:24241537 PMID:27472835 PMID:29067999 More... RGD:39939002, RGD:39938968 NCBI chr19:29,902,513...29,938,118
Ensembl chr19:29,902,514...29,938,118
JBrowse link
G Il4 interleukin 4 treatment
no_association
IMP
ISO
IEP
CTD Direct Evidence: marker/mechanism
mRNA, protein:increase expression:leukocyte, serum
protein:increased expression:lung
DNA:SNP: :589C>T (human)
DNA:polymorphism (human)
mRNA:increased expression:lung, spleen
protein:increased expression:respiratory system fluid/secretion
CTD
RGD
PMID:18357729 PMID:21375458 PMID:24946644 PMID:24450480 PMID:18211752 More... RGD:5128557, RGD:10402799, RGD:10402791, RGD:2317290, RGD:5128560, RGD:4889866, RGD:5128500, RGD:5128502 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
JBrowse link
G Il4ra interleukin 4 receptor, alpha susceptibility
severity
disease_progression
ISO
IEA
IMP
DNA:polymorphism:cds:p.Q551R (human)
OMIM:600807
DNA:polymorphism:cds:p.I50V (human)
DNA:polymorphism::-1902G/A (human)
DNA:SNPs: :multiple
DNA:SNPs:cds:p. I75V, Q576R (human)
protein:increased secretion:plasma|DNA:polymorphism:promoter:c.-3223C>T (human)
DNA:SNPs:cds:p.E375A, Q551R (human)
DNA:polymorphism:cds:p.Q576R (human)
DNA:polymorphism:cds:p. S478P (human)
DNA:mutation:cds:p.Q576R (mouse)
MouseDO
RGD
PMID:17586032 PMID:18425216 PMID:20868478 PMID:17823973 PMID:11398072 More... RGD:4890348, RGD:4890346, RGD:4890387, RGD:4890347, RGD:4890406, RGD:4890404, RGD:4890351, RGD:4890349, RGD:4890402, RGD:4890024, RGD:5128514, RGD:5128553, RGD:4890003, RGD:4890352 NCBI chr 7:125,151,443...125,178,646
Ensembl chr 7:125,151,292...125,178,646
JBrowse link
G Il5 interleukin 5 treatment
disease_progression
IEP
ISO
IMP
protein:increased expression:respiratory system fluid/secretion
CTD Direct Evidence: marker/mechanism
protein:increased expression:lungs, respiratory system fluid/secretion
protein: increased levels: sputum
DNA:polymorphism:promoter:-703C>T (human)
CTD
RGD
PMID:7540862 PMID:23266719 PMID:15626484 PMID:25008888 PMID:11159041 More... RGD:4890947, RGD:11354973, RGD:5687189, RGD:5687144, RGD:5687140, RGD:4890948, RGD:4890963, RGD:4145461, RGD:4890962, RGD:4890940, RGD:4890938 NCBI chr11:53,611,621...53,615,930
Ensembl chr11:53,611,621...53,615,933
JBrowse link
G Il5ra interleukin 5 receptor, alpha IMP
ISO
DNA:SNP: :c.25091G>A (human)
DNA:SNPs (human)
RGD PMID:10848907 PMID:20592918 PMID:17276963 PMID:10224351 PMID:16217591 More... RGD:5128627, RGD:5128614, RGD:5128617, RGD:5128623, RGD:5128626, RGD:5128625 NCBI chr 6:106,687,336...106,725,998
Ensembl chr 6:106,687,318...106,725,998
JBrowse link
G Il6 interleukin 6 IDA
ISO
CTD Direct Evidence: marker/mechanism
associated with Hypersensitivity;protein:increased expression:sputum
protein:increased expression:lung
CTD
RGD
PMID:29902480 PMID:21115736 PMID:20840469 PMID:20816188 PMID:20658762 RGD:5128630, RGD:4143265, RGD:4143266, RGD:4143271 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Il6ra interleukin 6 receptor, alpha IMP
ISO
IDA
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:29902480 PMID:17496315 PMID:21115736 RGD:5128662, RGD:5128630 NCBI chr 3:89,776,631...89,820,503
Ensembl chr 3:89,771,366...89,820,503
JBrowse link
G Il9 interleukin 9 ISO
IMP
IEP
protein:increased expression:respiratory system fluid/secretion
protein:increased expression:sputum, macrophage, cytoplasm
RGD PMID:21356110 PMID:17446528 PMID:15531759 PMID:15303135 PMID:12153980 RGD:5128707, RGD:5128686, RGD:5128690, RGD:5128691, RGD:5128700 NCBI chr13:56,627,090...56,630,070
Ensembl chr13:56,627,090...56,630,059
JBrowse link
G Il9r interleukin 9 receptor ISO RGD PMID:10629460 RGD:5128704 NCBI chr11:32,137,544...32,155,283
Ensembl chr11:32,137,541...32,150,279
JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 susceptibility ISO ClinVar Annotator: match by term: Asthma-related traits, susceptibility to, 5
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
PMID:17503328 NCBI chr10:119,977,553...120,038,035
Ensembl chr10:119,977,553...120,038,035
JBrowse link
G Irf1 interferon regulatory factor 1 no_association
susceptibility
ISO DNA:polymorphisms:promoter, cds:-300G>T, 4396A>G, 6355G>A (human)
DNA:repeat:intron (human)
protein:increased expression:respiratory tract epithelium
RGD PMID:11069564 PMID:16961714 PMID:10225979 RGD:5128726, RGD:5128724, RGD:5128723 NCBI chr11:53,660,841...53,669,200
Ensembl chr11:53,660,841...53,669,200
JBrowse link
G Irf3 interferon regulatory factor 3 IMP RGD PMID:20673978 RGD:5128793 NCBI chr 7:44,647,072...44,652,272
Ensembl chr 7:44,647,072...44,652,272
JBrowse link
G Itgb3 integrin beta 3 ISO DNA:SNPs: : RGD PMID:17556058 RGD:5037230 NCBI chr11:104,498,826...104,561,302
Ensembl chr11:104,498,826...104,561,302
JBrowse link
G Itgb6 integrin beta 6 IEA OMIM:600807 MouseDO NCBI chr 2:60,428,636...60,553,005
Ensembl chr 2:60,428,636...60,552,987
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor 1 ISO RGD PMID:21777465 RGD:5147661 NCBI chr 6:108,190,044...108,528,077
Ensembl chr 6:108,190,057...108,528,070
JBrowse link
G Kdr kinase insert domain protein receptor IMP
ISO
associated with Rhinitis,Allergic,Seasonal;protein:increased expression:nasal cavity of mucosa: RGD PMID:20921519 PMID:17651148 RGD:5684385, RGD:8551771 NCBI chr 5:76,093,487...76,139,885
Ensembl chr 5:76,093,487...76,139,118
JBrowse link
G Kif3a kinesin family member 3A ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chr11:53,456,531...53,495,075
Ensembl chr11:53,458,206...53,492,794
JBrowse link
G Krt19 keratin 19 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15478392 NCBI chr11:100,031,636...100,036,752
Ensembl chr11:100,031,636...100,039,491
JBrowse link
G Lep leptin ISO protein:increased expression:plasma RGD PMID:19705789 RGD:5128781 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876
JBrowse link
G Lgals3 lectin, galactose binding, soluble 3 treatment ISO RGD PMID:16424226 RGD:9685213 NCBI chr14:47,611,317...47,623,624
Ensembl chr14:47,605,208...47,623,617
JBrowse link
G Lta lymphotoxin A susceptibility
no_association
ISO DNA:polymorphisms:promoter
DNA:polymorphism:intron
RGD PMID:15969671 PMID:18947013 PMID:17536219 PMID:12530118 RGD:4143373, RGD:4143370, RGD:4143371, RGD:4143254 NCBI chr17:35,422,141...35,424,568
Ensembl chr17:35,422,141...35,424,327
JBrowse link
G Lta4h leukotriene A4 hydrolase ISO mRNA:increased expression:lung, cerebral cortex (rat) RGD PMID:15715933 RGD:2316607 NCBI chr10:93,289,258...93,320,758
Ensembl chr10:93,289,273...93,320,737
JBrowse link
G Mbl2 mannose-binding lectin (protein C) 2 susceptibility ISO associated with Bronchiolitis;DNA:polymorphism:exon:
DNA:SNP:cds:p.G54D(human)
RGD PMID:22512728 PMID:22674410 RGD:8693709, RGD:12910828 NCBI chr19:30,210,306...30,217,087
Ensembl chr19:30,210,342...30,217,087
JBrowse link
G Mefv Mediterranean fever susceptibility ISO DNA:mutations:exons RGD PMID:18219832 RGD:5129186 NCBI chr16:3,524,838...3,536,073
Ensembl chr16:3,525,082...3,535,961
JBrowse link
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) severity ISO
IMP
protein:increased expression:bronchoalveolar lavage fluid
DNA:SNP:promoter:rs755622(human)
DNA:repeats:promoter
RGD PMID:9637721 PMID:19317738 PMID:17373669 PMID:16186482 PMID:16455830 RGD:4891043, RGD:4891059, RGD:4891035, RGD:4891052, RGD:1641985 NCBI chr10:75,695,187...75,696,111
Ensembl chr10:75,695,187...75,696,074
JBrowse link
G Mmp10 matrix metallopeptidase 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16926187 NCBI chr 9:7,502,343...7,510,243
Ensembl chr 9:7,502,353...7,510,241
JBrowse link
G Mmp1b matrix metallopeptidase 1b (interstitial collagenase) ISO CTD Direct Evidence: marker/mechanism CTD PMID:24469321 NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047
JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
protein:increased expression:lung
DNA:SNP: : rs2664538(human)
mRNA, protein:increased expression:lung
CTD
RGD
PMID:11742282 PMID:15131573 PMID:21439806 PMID:19361849 PMID:20181264 More... RGD:5129204, RGD:5129687, RGD:5130859, RGD:2325953, RGD:5129522 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
JBrowse link
G Mpo myeloperoxidase susceptibility ISO DNA:polymorphism: :−463G > A (human)
protein:increased expression:serum
RGD PMID:19544176 PMID:10731862 RGD:5130989, RGD:5130994 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
JBrowse link
G Ms4a2 membrane-spanning 4-domains, subfamily A, member 2 susceptibility ISO DNA:SNPs:multiple:, rs573790, rs2583476, rs569108
DNA:SNPs: : rs556917, rs502581, rs502419 (human)
DNA:SNP: : -109C>T (human)
Atopy and bronchial hyperresponsiveness, OMIM:147050
RGD PMID:19218813 PMID:21320344 PMID:19862939 PMID:8817330 RGD:5131151, RGD:5131149, RGD:5131092, RGD:1599903 NCBI chr19:11,592,881...11,601,154
Ensembl chr19:11,592,887...11,601,083
JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO DNA:transition:cds:g.677C>T (human) RGD PMID:20456312 RGD:4891145 NCBI chr 4:148,123,534...148,144,019
Ensembl chr 4:148,123,534...148,144,008
JBrowse link
G Muc1 mucin 1, transmembrane ISO protein:increased expression:serum RGD PMID:11802251 RGD:5131281 NCBI chr 3:89,136,363...89,140,688
Ensembl chr 3:89,136,364...89,140,688
JBrowse link
G Muc2 mucin 2 ISO
IEP
associated with hypersensitivity RGD PMID:11062147 PMID:14594655 RGD:5131178, RGD:7349354 NCBI chr 7:141,276,583...141,308,428
Ensembl chr 7:141,276,583...141,308,430
JBrowse link
G Muc5ac mucin 5, subtypes A and C, tracheobronchial/gastric treatment ISO
IDA
IEP
protein:increased expression:lung
mRNA, protein:increased expression:lung
mRNA,protein:increased expression:lung
RGD PMID:17698377 PMID:21549818 PMID:21780541 PMID:14594655 PMID:17590487 RGD:5131204, RGD:7364729, RGD:7349407, RGD:7349354, RGD:2324962 NCBI chr 7:141,342,695...141,372,964
Ensembl chr 7:141,342,709...141,372,968
JBrowse link
G Muc5b mucin 5, subtype B, tracheobronchial ISO
IEP
protein:altered expression:sputum RGD PMID:11802783 PMID:11587997 RGD:5131252, RGD:7364763 NCBI chr 7:141,392,796...141,426,826
Ensembl chr 7:141,392,807...141,426,821
JBrowse link
G Myb myeloblastosis oncogene ISO CTD Direct Evidence: marker/mechanism CTD PMID:19198610 NCBI chr10:21,000,829...21,036,883
Ensembl chr10:21,000,834...21,036,883
JBrowse link
G Myd88 myeloid differentiation primary response gene 88 ameliorates IMP RGD PMID:26882889 RGD:11531666 NCBI chr 9:119,165,000...119,169,084
Ensembl chr 9:119,165,000...119,170,477
JBrowse link
G Mylk myosin, light polypeptide kinase ISO RGD PMID:17472811 RGD:4891492 NCBI chr16:34,565,569...34,822,806
Ensembl chr16:34,565,580...34,822,790
JBrowse link
G Nat2 N-acetyltransferase 2 (arylamine N-acetyltransferase) susceptibility ISO DNA:polymorphisms: :
Asthma, Aspirin-Induced; DNA:polymorphism: :
RGD PMID:16924569 PMID:20602614 RGD:5131606, RGD:5131600 NCBI chr 8:67,947,527...67,955,296
Ensembl chr 8:67,947,510...67,955,236
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 severity ISO mRNA:increased expression:bronchoalveolar lavage cell, peripheral blood mononuclear cell (human) RGD PMID:21514635 RGD:6893376 NCBI chr 2:75,505,857...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Ngf nerve growth factor severity ISO
IEP
protein:increased expression:blood, eosinophil
protein:increased expression:lung, serum
RGD PMID:12752594 PMID:17164945 PMID:11737043 PMID:17497413 RGD:4891122, RGD:4891108, RGD:4891123, RGD:4891068 NCBI chr 3:102,377,235...102,428,329
Ensembl chr 3:102,377,235...102,428,329
JBrowse link
G Ngfr nerve growth factor receptor (TNFR superfamily, member 16) IMP RGD PMID:16603479 PMID:12540484 RGD:5144070, RGD:5144072 NCBI chr11:95,459,644...95,478,524
Ensembl chr11:95,459,644...95,478,561
JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 susceptibility ISO DNA:SNP: :rs2075817 (human)
DNA:insertion:cds:
RGD PMID:16918516 PMID:15718249 RGD:5131519, RGD:5131518 NCBI chr 6:54,900,927...54,949,655
Ensembl chr 6:54,900,934...54,949,597
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 susceptibility ISO
IDA
DNA:polymorphisms:intron, exon/3'UTR (rs1077861, rs3135500) (human) RGD PMID:16008671 PMID:21051079 RGD:5131477, RGD:5508757 NCBI chr 8:89,373,943...89,415,103
Ensembl chr 8:89,373,943...89,415,102
JBrowse link
G Nos1 nitric oxide synthase 1, neuronal susceptibility ISO DNA:repeats:exon
DNA:repeats:intron
DNA:repeats: :
RGD PMID:10833424 PMID:14767694 PMID:10673365 PMID:20609134 RGD:5132860, RGD:5132615, RGD:5132869, RGD:5132863 NCBI chr 5:118,004,904...118,096,905
Ensembl chr 5:117,919,097...118,096,905
JBrowse link
G Nos2 nitric oxide synthase 2, inducible severity
disease_progression
no_association
IMP
ISO
IEP
CTD Direct Evidence: marker/mechanism
protein:increased expression, increased activity:lung (rat)
DNA:repeats:promoter
protein:increased expression:lung, bronchoalveolar lavage fluid
associated with Rhinitis, Allergic, Seasonal; protein:increased expression:nasal mucosa
DNA:repeats:promoter, introns (human)
DNA:SNP:exon:p.S608L (human)
mRNA:increased expression:monocyte
DNA:repeat:promoter
CTD
RGD
PMID:19800904 PMID:20841959 PMID:21847581 PMID:18714530 PMID:17161822 More... RGD:4891480, RGD:5509073, RGD:4891508, RGD:4891927, RGD:4891910, RGD:4891924, RGD:4891925, RGD:4891419, RGD:4891957, RGD:4891953 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell susceptibility ISO DNA:snps, repeat, haplotype:promoter, introns, exons:multiple (human)
DNA:polymorphisms:promoter:c. -786C>T, -691C>T (human)
DNA:repeats:intron
RGD PMID:18486767 PMID:16837812 PMID:16081038 RGD:4892053, RGD:4892058, RGD:4892062 NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472
JBrowse link
G Npsr1 neuropeptide S receptor 1 susceptibility ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Asthma-related traits, susceptibility to, 2
CTD
OMIM
ClinVar
RGD
PMID:15073379 PMID:15710598 PMID:15764725 PMID:16926187 PMID:15073379 More... RGD:4891921, RGD:4891922, RGD:4891923 NCBI chr 9:24,009,212...24,229,151
Ensembl chr 9:24,009,292...24,227,694
JBrowse link
G Npy neuropeptide Y ISO CTD Direct Evidence: marker/mechanism CTD PMID:9731035 NCBI chr 6:49,799,690...49,806,487
Ensembl chr 6:49,799,690...49,806,487
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 susceptibility ISO DNA:SNP:exon:c. 609C>T (human)
CTD Direct Evidence: marker/mechanism
DNA:SNP:exon:c.609C>T (human)
CTD
RGD
PMID:20049212 PMID:19027876 PMID:19591959 RGD:5135006, RGD:5135005 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 treatment
susceptibility
severity
ISO DNA:polymorphism:intron
protein:increased expression, decreased activity:leukocyte, mononuclear
RGD PMID:18396779 PMID:20727335 PMID:21113676 PMID:18799869 PMID:15295049 RGD:4892328, RGD:7174728, RGD:4892568, RGD:4892594, RGD:4892609 NCBI chr18:39,543,598...39,652,485
Ensembl chr18:39,543,598...39,652,474
JBrowse link
G Ntf3 neurotrophin 3 IEP
ISO
protein:increased expression:lung, serum RGD PMID:17497413 PMID:11737043 RGD:4891068, RGD:4891123 NCBI chr 6:126,078,375...126,143,734
Ensembl chr 6:126,078,375...126,143,873
JBrowse link
G Ntf5 neurotrophin 5 IEP protein:increased expression:lung, serum RGD PMID:17497413 RGD:4891068 NCBI chr 7:45,063,119...45,066,603
Ensembl chr 7:45,063,119...45,066,603
JBrowse link
G Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 IMP
ISO
mRNA:increased expression:lung: RGD PMID:20934630 PMID:16708804 RGD:5684766, RGD:5684772 NCBI chr 3:87,685,551...87,702,549
Ensembl chr 3:87,685,551...87,702,469
JBrowse link
G Ormdl3 ORM1-like 3 (S. cerevisiae) ISO CTD Direct Evidence: marker/mechanism CTD PMID:21150878 PMID:25256354 NCBI chr11:98,472,120...98,478,071
Ensembl chr11:98,472,082...98,478,194
JBrowse link
G P2ry12 purinergic receptor P2Y, G-protein coupled 12 ISO
IMP
RGD PMID:22010907 PMID:19822647 RGD:6480532, RGD:6480533 NCBI chr 3:59,123,692...59,170,408
Ensembl chr 3:59,123,693...59,170,292
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 treatment IMP
ISO
CTD Direct Evidence: marker/mechanism
protein:increased activation:lung, blood, mononuclear cell
CTD
RGD
PMID:18261157 PMID:12594058 PMID:26205779 PMID:26205779 RGD:5683910, RGD:11073727, RGD:11073727 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
JBrowse link
G Pdcd1 programmed cell death 1 treatment IMP associated with Chlamydia pneumonia RGD PMID:26378990 RGD:41412180 NCBI chr 1:93,966,027...93,980,278
Ensembl chr 1:93,966,027...93,980,278
JBrowse link
G Pde4b phosphodiesterase 4B, cAMP specific ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chr 4:101,944,529...102,464,472
Ensembl chr 4:101,944,740...102,464,456
JBrowse link
G Pde4d phosphodiesterase 4D, cAMP specific ISO CTD Direct Evidence: marker/mechanism CTD PMID:19426955 PMID:21611147 NCBI chr13:108,790,711...110,092,503
Ensembl chr13:108,586,482...110,089,995
JBrowse link
G Pdgfb platelet derived growth factor, B polypeptide IEP
ISO
protein: increased expression RGD PMID:21216974 PMID:21216974 RGD:6483071, RGD:6483071 NCBI chr15:79,880,066...79,899,178
Ensembl chr15:79,880,075...79,899,178
JBrowse link
G Pgf placental growth factor IMP RGD PMID:22268141 RGD:6483605 NCBI chr12:85,213,411...85,224,559
Ensembl chr12:85,213,409...85,224,564
JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma IMP RGD PMID:18754810 RGD:6482695 NCBI chr12:32,223,128...32,258,675
Ensembl chr12:32,223,472...32,258,658
JBrowse link
G Pin1 peptidyl-prolyl cis/trans isomerase, NIMA-interacting 1 IMP RGD PMID:18188456 RGD:8693422 NCBI chr 9:20,563,335...20,575,008
Ensembl chr 9:20,563,391...20,577,880
JBrowse link
G Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) ISO RGD PMID:15557087 RGD:1642462 NCBI chr 1:149,705,369...149,837,041
Ensembl chr 1:149,705,369...149,837,041
JBrowse link
G Pla2g7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) susceptibility ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Asthma and atopy, susceptibility to
OMIM
CTD
ClinVar
RGD
PMID:10733466 PMID:15115767 PMID:10733466 RGD:1581025 NCBI chr17:43,878,885...43,923,093
Ensembl chr17:43,878,989...43,923,092
JBrowse link
G Plau plasminogen activator, urokinase ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:21912604 PMID:18519237 RGD:4892037 NCBI chr14:20,886,730...20,893,456
Ensembl chr14:20,886,728...20,893,453
JBrowse link
G Ppp2ca protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform ISO CTD Direct Evidence: marker/mechanism CTD PMID:22205926 NCBI chr11:51,989,651...52,013,576
Ensembl chr11:51,989,508...52,018,605
JBrowse link
G Prf1 perforin 1 (pore forming protein) IMP
ISO
RGD PMID:22250087 PMID:21426642 RGD:6482815, RGD:6482818 NCBI chr10:61,133,530...61,140,463
Ensembl chr10:61,133,612...61,140,459
JBrowse link
G Prg2 proteoglycan 2, bone marrow severity
disease_progression
no_association
ISO
IMP
mRNA:increased expression:eosinophil:
associated with cough;protein:increased expression:sputum:
associated with viral infection;mRNA:increased expression:sputum:
RGD PMID:16982448 PMID:22022864 PMID:24450586 PMID:11067904 RGD:13506941, RGD:13506944, RGD:13506943, RGD:13506942 NCBI chr 2:84,810,805...84,813,977
Ensembl chr 2:84,810,805...84,813,976
JBrowse link
G Prmt1 protein arginine N-methyltransferase 1 ISO mRNA:increased expression:lung RGD PMID:20423833 RGD:9491823 NCBI chr 7:44,626,179...44,635,844
Ensembl chr 7:44,625,413...44,635,992
JBrowse link
G Prmt2 protein arginine N-methyltransferase 2 ISO mRNA:increased expression:lung, spleen RGD PMID:20423833 RGD:9491823 NCBI chr10:76,043,060...76,073,699
Ensembl chr10:76,043,056...76,073,699
JBrowse link
G Prmt3 protein arginine N-methyltransferase 3 ISO mRNA:increased expression:lung RGD PMID:20423833 RGD:9491823 NCBI chr 7:49,428,067...49,508,016
Ensembl chr 7:49,428,094...49,508,013
JBrowse link
G Prmt5 protein arginine N-methyltransferase 5 ISO mRNA:increased expression:lung, spleen RGD PMID:20423833 RGD:9491823 NCBI chr14:54,744,639...54,754,927
Ensembl chr14:54,744,644...54,754,982
JBrowse link
G Proc protein C treatment ISO RGD PMID:26381519 RGD:11099992 NCBI chr18:32,256,179...32,272,623
Ensembl chr18:32,256,179...32,272,623
JBrowse link
G Prol1 proline rich, lacrimal 1 susceptibility ISO ClinVar Annotator: match by term: Asthma, protection against
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
PMID:11378823 PMID:16759176 NCBI chr 5:88,465,171...88,476,676
Ensembl chr 5:88,465,171...88,476,673
JBrowse link
G Pten phosphatase and tensin homolog ISO CTD Direct Evidence: therapeutic CTD PMID:17982072 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560
JBrowse link
G Ptgdr prostaglandin D receptor susceptibility ISO CTD Direct Evidence: marker/mechanism OMIM
CTD
NCBI chr14:45,088,692...45,096,832
Ensembl chr14:45,088,692...45,096,832
JBrowse link
G Ptgdr2 prostaglandin D2 receptor 2 ISO
IMP
Aspirin exacerbated asthma
CTD Direct Evidence: therapeutic
CTD
RGD
PMID:27103662 PMID:19796209 PMID:19392992 PMID:18757520 RGD:5135020, RGD:5135019, RGD:5135018 NCBI chr19:10,901,883...10,919,875
Ensembl chr19:10,914,524...10,919,875
JBrowse link
G Ptger3 prostaglandin E receptor 3 (subtype EP3) treatment ISO RGD PMID:23221044 RGD:10043366 NCBI chr 3:157,272,459...157,350,392
Ensembl chr 3:157,272,529...157,351,525
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 susceptibility
severity
ISO
IEP
IMP
mRNA:increased expression:lung
DNA:SNP: :8473T>C (human)
mRNA, protein:increased expression:lung:
DNA:SNP: :rs689465 (human)
RGD PMID:19862936 PMID:19878559 PMID:15316498 PMID:17573729 PMID:18097056 More... RGD:5135515, RGD:5135514, RGD:5143931, RGD:5143923, RGD:5135534, RGD:5135526, RGD:5135522 NCBI chr 1:149,975,782...149,983,985
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Rad50 RAD50 double strand break repair protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:24241537 NCBI chr11:53,540,346...53,598,146
Ensembl chr11:53,540,346...53,598,146
JBrowse link
G Rhoa ras homolog family member A ISO RGD PMID:18391481 RGD:2298885 NCBI chr 9:108,183,359...108,215,142
Ensembl chr 9:108,183,328...108,215,133
JBrowse link
G Runx1 runt related transcription factor 1 ISO DNA:SNPs: :multiple RGD PMID:21803869 RGD:6482835 NCBI chr16:92,398,354...92,622,962
Ensembl chr16:92,398,354...92,623,037
JBrowse link
G Runx3 runt related transcription factor 3 IEA OMIM:600807 MouseDO NCBI chr 4:134,847,956...134,905,301
Ensembl chr 4:134,847,963...134,905,301
JBrowse link
G Scgb1a1 secretoglobin, family 1A, member 1 (uteroglobin) susceptibility ISO mRNA,protein:decreased expression:bronchial alveolar lavage fluid, lung:
ClinVar Annotator: match by term: Asthma, susceptibility to
associated with allergic rhinitis; DNA:SNP:exon:38G>A (human)
protein:decreased expression:serum
ClinVar
RGD
PMID:9550363 PMID:12921604 PMID:21255142 PMID:15467329 RGD:5144052, RGD:5144226, RGD:5144148 NCBI chr19:9,061,006...9,065,320
Ensembl chr19:9,061,000...9,065,322
JBrowse link
G Scgb3a2 secretoglobin, family 3A, member 2 susceptibility
severity
no_association
ISO
IEP
IDA
DNA:SNP:promoter:-112G>A (human)
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Asthma, susceptibility to
mRNA,protein:decreased expression:;lung
protein:increased expression:sputum
CTD
OMIM
ClinVar
RGD
PMID:11813133 PMID:11813133 PMID:15531759 PMID:16456148 PMID:17218572 More... RGD:5144229, RGD:5128690, RGD:5144233, RGD:5144232, RGD:5144231, RGD:5144230 NCBI chr18:43,897,346...43,900,464
Ensembl chr18:43,897,354...43,900,464
JBrowse link
G Sell selectin, lymphocyte IMP RGD PMID:21437035 PMID:21515793 RGD:5685685, RGD:5685696 NCBI chr 1:163,889,556...163,908,354
Ensembl chr 1:163,889,551...163,911,750
JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 severity
susceptibility
no_association
ISO protein:increased expression:plasma
DNA:polymorphism:promoter:rs1799768 (human)
protein:increased activity, increased expression:plasma, lung
RGD PMID:19703828 PMID:19063817 PMID:19604112 PMID:18594148 RGD:4144831, RGD:4144832, RGD:4144833, RGD:4144836 NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122
JBrowse link
G Sftpa1 surfactant associated protein A1 ISO
IEP
protein:decreased expression:lung, Clara cell, pneumocyte
mRNA, protein:increased expression:lung
RGD PMID:15816355 PMID:16629790 PMID:18926058 PMID:18802356 RGD:4143398, RGD:4143462, RGD:4143289, RGD:4143516 NCBI chr14:40,853,745...40,858,330
Ensembl chr14:40,853,739...40,858,409
JBrowse link
G Sftpb surfactant associated protein B ISO
IEP
protein:increased expression:lung
mRNA, protein:decreased expression:lung
protein:decreased expression:lung, Clara cell
RGD PMID:16629790 PMID:11472974 PMID:15816355 PMID:18926058 RGD:4143462, RGD:4143465, RGD:4143398, RGD:4143289 NCBI chr 6:72,281,594...72,291,356
Ensembl chr 6:72,281,594...72,291,354
JBrowse link
G Sftpc surfactant associated protein C susceptibility ISO
IEP
DNA:polymorphism: :p.A53T (human)
protein:increased expression:lung
mRNA, protein:decreased expression:lung
RGD PMID:19910179