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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:hepatorenal syndrome
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Accession:DOID:11823 term browser browse the term
Definition:An acute kidney failure that is characterized by severe renal vasoconstriction. (DO)
Synonyms:primary_id: MESH:D006530
 xref: GARD:6610;   ICD10CM:K76.7;   ICD9CM:572.4;   NCI:C113400
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
hepatorenal syndrome term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edn1 endothelin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:7967349 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Hmox1 heme oxygenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21253390 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Sod1 superoxide dismutase 1 ISO RGD PMID:15531919 RGD:1581228 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Tlr4 toll-like receptor 4 IEP mRNA, protein:increased expression:kidney RGD PMID:18093430 RGD:4144102 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tnf tumor necrosis factor IEP protein:increased expression:plasma RGD PMID:18093430 RGD:4144102 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 21108
    syndrome 10708
      hepatorenal syndrome 5
Path 2
Term Annotations click to browse term
  disease 21108
    disease of anatomical entity 18147
      Urogenital Diseases 5119
        urinary system disease 2751
          kidney disease 2524
            kidney failure 562
              acute kidney failure 325
                hepatorenal syndrome 5
paths to the root