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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:pyelonephritis
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Accession:DOID:11400 term browser browse the term
Definition:Inflammation of the KIDNEY involving the renal parenchyma (the NEPHRONS); KIDNEY PELVIS; and KIDNEY CALICES. It is characterized by ABDOMINAL PAIN; FEVER; NAUSEA; VOMITING; and occasionally DIARRHEA.
Synonyms:exact_synonym: Necrotizing Pyelonephritis;   Pyelonephritides;   Pyelonephritis, Acute Necrotizing
 primary_id: MESH:D011704
 xref: EFO:1001141;   ICD10CM:N16;   ICD9CM:590.80;   NCI:C34965
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
pyelonephritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme ISO protein:decreased expression:kidney, brush border epithelial cell (human) RGD PMID:10504496 RGD:8158033 NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790 		JBrowse link
G Ambp alpha 1 microglobulin/bikunin precursor ISO RGD PMID:19205372 RGD:6904156 NCBI chr 4:63,061,512...63,072,409
Ensembl chr 4:63,061,512...63,073,036 		JBrowse link
G B2m beta-2 microglobulin ISO RGD PMID:21797109 RGD:6482315 NCBI chr 2:121,978,168...121,983,563
Ensembl chr 2:121,978,167...121,983,564 		JBrowse link
G Bmp7 bone morphogenetic protein 7 ISO protein:decreased expression:kidney RGD PMID:16034630 RGD:2289039 NCBI chr 2:172,709,805...172,782,114
Ensembl chr 2:172,709,805...172,782,114 		JBrowse link
G Calca calcitonin/calcitonin-related polypeptide, alpha ISO RGD PMID:15286264 RGD:7205498 NCBI chr 7:114,225,223...114,236,145
Ensembl chr 7:114,230,713...114,235,592 		JBrowse link
G Cfb complement factor B ISO associated with pregnancy complications;protein:increased activity:plasma RGD PMID:20218820 RGD:7242756 NCBI chr17:35,075,350...35,081,492
Ensembl chr17:35,075,350...35,081,494 		JBrowse link
G Crp C-reactive protein, pentraxin-related ISO RGD PMID:21797109 RGD:6482315 NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598 		JBrowse link
G Cxcr1 C-X-C motif chemokine receptor 1 ISO DNA:SNP: :2608G>C (human)
DNA:mutations, polymorphisms: :multiple 		RGD PMID:22325052 PMID:17786197 RGD:7207860, RGD:7207864 NCBI chr 1:74,228,862...74,233,867
Ensembl chr 1:74,230,944...74,233,790 		JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 IMP RGD PMID:21814172 RGD:7257675 NCBI chr 1:74,193,153...74,200,405
Ensembl chr 1:74,193,150...74,200,405 		JBrowse link
G Cyb5a cytochrome b5 type A (microsomal) ISO RGD PMID:9848217 RGD:1599663 NCBI chr18:84,869,463...84,897,996
Ensembl chr18:84,856,829...84,897,996 		JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO protein:increased expression:urine (human) RGD PMID:8640042 RGD:6907372 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506 		JBrowse link
G Il3 interleukin 3 ISO mRNA:increased expression:kidney RGD PMID:18214547 RGD:2317665 NCBI chr11:54,155,911...54,158,105
Ensembl chr11:54,156,129...54,158,103 		JBrowse link
G Pgf placental growth factor ISO protein:decreased expression:plasma RGD PMID:20213923 RGD:6483586 NCBI chr12:85,213,413...85,224,087
Ensembl chr12:85,213,409...85,224,564 		JBrowse link
G Pim1 proviral integration site 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23565217 NCBI chr17:29,709,759...29,715,085
Ensembl chr17:29,709,727...29,715,086 		JBrowse link
G Retn resistin ISO protein:increased expression:plasma RGD PMID:20178460 RGD:7207160 NCBI chr 8:3,705,770...3,709,818
Ensembl chr 8:3,705,770...3,710,110 		JBrowse link
G Tlr1 toll-like receptor 1 susceptibility ISO DNA:snp:cds:p.S602I (human) RGD PMID:19543401 RGD:7246906 NCBI chr 5:65,082,023...65,090,945
Ensembl chr 5:65,082,022...65,090,906 		JBrowse link
acute pyelonephritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cxcl15 C-X-C motif chemokine ligand 15 susceptibility ISO DNA:SNP:promoter:g.-251T>A (rs4073) (human) RGD PMID:22325052 RGD:7207860 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926 		JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 susceptibility ISO DNA:polymorphism:3' utr:1208C>T (human) RGD PMID:22325052 RGD:7207860 NCBI chr 1:74,193,153...74,200,405
Ensembl chr 1:74,193,150...74,200,405 		JBrowse link
G Rbp4 retinol binding protein 4, plasma ISO protein:decreased expression:blood plasma (human) RGD PMID:20163326 RGD:329853301 NCBI chr19:38,105,068...38,113,769
Ensembl chr19:38,105,077...38,113,729 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16271
    Pathological Conditions, Signs and Symptoms 12654
      Pathologic Processes 8071
        Inflammation 2608
          nephritis 423
            pyelitis 18
              pyelonephritis 18
                acute pyelonephritis 3
                chronic pyelonephritis + 0
                xanthogranulomatous pyelonephritis 0
Path 2
Term Annotations click to browse term
  disease 16271
    disease of anatomical entity 15863
      Urogenital Diseases 5076
        urinary system disease 2512
          kidney disease 2258
            nephritis 423
              interstitial nephritis 45
                pyelonephritis 18
                  acute pyelonephritis 3
                  chronic pyelonephritis + 0
                  xanthogranulomatous pyelonephritis 0
paths to the root