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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:pneumocystosis
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Accession:DOID:11339 term browser browse the term
Definition:A pulmonary disease in humans occurring in immunodeficient or malnourished patients or infants, characterized by DYSPNEA, tachypnea, and HYPOXEMIA. Pneumocystis pneumonia is a frequently seen opportunistic infection in AIDS. It is caused by the fungus PNEUMOCYSTIS JIROVECII. The disease is also found in other MAMMALS where it is caused by related species of Pneumocystis.
Synonyms:exact_synonym: Pneumocystis Pneumonias;   Pneumocystis carinii Pneumonia;   Pneumocystis jirovecii pneumonia;   Pneumocystoses;   Pneumocystosis pneumonia;   Pneumonia, Interstitial Plasma Cell;   Pneumonia, Pneumocystis;   Pneumonias, Pneumocystis carinii;   pulmonary pneumocystosis
 primary_id: MESH:D011020
 alt_id: RDO:0006374
 xref: GARD:4386;   ICD10CM:B59;   ICD9CM:136.3;   NCI:C3334
For additional species annotation, visit the Alliance of Genome Resources.


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pneumocystosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Azin1 antizyme inhibitor 1 ISO mRNA:increased expression:alveolar macrophage RGD PMID:19158080 RGD:14700806 NCBI chrNW_004955417:27,231,695...27,259,564
Ensembl chrNW_004955417:27,231,696...27,259,564
JBrowse link
G C3 complement C3 ISO RGD PMID:17169032 RGD:5129525 NCBI chrNW_004955495:2,796,601...2,824,233
Ensembl chrNW_004955495:2,796,663...2,824,697
JBrowse link
G Cd40 CD40 molecule treatment ISO RGD PMID:10968950 RGD:8547797 NCBI chrNW_004955445:11,191,817...11,202,156
Ensembl chrNW_004955445:11,190,603...11,202,093
JBrowse link
G Csf2 colony stimulating factor 2 ISO protein:increased expression:respiratory system fluid/secretion RGD PMID:19487471 RGD:5131475 NCBI chrNW_004955408:3,452,009...3,454,255
Ensembl chrNW_004955408:3,451,965...3,454,312
JBrowse link
G Il23a interleukin 23 subunit alpha ISO RGD PMID:17403873 RGD:39458043 NCBI chrNW_004955458:3,946,964...3,949,180
Ensembl chrNW_004955458:3,947,803...3,949,312
JBrowse link
G Il33 interleukin 33 treatment ISO RGD PMID:21220696 RGD:40400892 NCBI chrNW_004955434:10,145,449...10,187,595
Ensembl chrNW_004955434:10,171,812...10,188,948
JBrowse link
G Muc1 mucin 1, cell surface associated ISO protein:increased expression:serum RGD PMID:9617869 RGD:5131424 NCBI chrNW_004955545:1,657,728...1,662,112 JBrowse link
G Nos2 nitric oxide synthase 2 ISO protein:decreased dimerization:alveolar macrophage
mRNA:increased expression:alveolar macrophage
RGD PMID:20377877 PMID:20558778 RGD:4144112 RGD:4891486 NCBI chrNW_004955481:5,197,957...5,232,406
Ensembl chrNW_004955481:5,201,234...5,231,961
JBrowse link
G Sftpb surfactant protein B ISO protein:decreased expression:lung RGD PMID:11385364 RGD:4143431 NCBI chrNW_004955424:1,849,313...1,858,087
Ensembl chrNW_004955424:1,849,314...1,858,087
JBrowse link
G Sftpc surfactant protein C ISO protein:decreased expression:lung RGD PMID:11385364 RGD:4143431 NCBI chrNW_004955403:45,649,149...45,651,421
Ensembl chrNW_004955403:45,649,122...45,651,837
JBrowse link
G Sftpd surfactant protein D ISO protein:increased expression:lung RGD PMID:11385364 RGD:4143431 NCBI chrNW_004955510:213,468...226,096
Ensembl chrNW_004955510:213,438...225,896
JBrowse link
G Tlr2 toll like receptor 2 ISO RGD PMID:18400546 RGD:4145341 NCBI chrNW_004955471:8,011,710...8,019,063
Ensembl chrNW_004955471:8,014,910...8,017,258
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 12691
    Pathological Conditions, Signs and Symptoms 8355
      Pathologic Processes 5690
        Inflammation 1775
          pneumonia 228
            pneumocystosis 12
Path 2
Term Annotations click to browse term
  disease 12691
    disease by infectious agent 1640
      Bacterial Infections and Mycoses 653
        fungal infectious disease 113
          systemic mycosis 108
            opportunistic mycosis 101
              pneumocystosis 12
paths to the root