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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Hantavirus hemorrhagic fever with renal syndrome
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Accession:DOID:11266 term browser browse the term
Definition:A viral infectious disease that is a hemorrhagic fever, located in kidney, has_material_basis_in Orthohantavirus dobravaense, has_material_basis_in Orthohantavirus hantanense, has_material_basis_in Orthohantavirus puumalaense, has_material_basis_in Orthohantavirus seoulense, which are carried and transmitted by rodents. The infection has symptom headache, has symptom fever, has symptom muscle pains, has symptom facial flush, has symptom petechiae, has symptom proteinuria, and has symptom renal failure. (DO)
Synonyms:exact_synonym: HFRS;   Puumala virus nephropathy;   Russian hemorrhagic fever;   epidemic hemorrhagic fever;   epidemic hemorrhagic fevers;   hemorrhagic fever with renal syndrome;   hemorrhagic nephroso nephritis;   hemorrhagic nephroso-nephritides;   hemorrhagic nephrosonephritis
 primary_id: MESH:D006480
 xref: EFO:0007299;   ICD10CM:A98.5;   ICD9CM:078.6;   NCI:C84753
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
Hantavirus hemorrhagic fever with renal syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin severity ISO RGD PMID:14555823 RGD:11035280 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461 		JBrowse link
G Apoc3 apolipoprotein C-III disease_progression ISO RGD PMID:20797315 RGD:7207210 NCBI chr 9:46,144,348...46,146,934
Ensembl chr 9:46,144,231...46,146,934 		JBrowse link
G Cd163 CD163 antigen exacerbates ISO protein:increased expression:blood plasma (human)
protein:increased expression:CD14-positive monocyte (human)
protein:increased expression:CD14-positive, CD16-positive monocyte, blood plasma (human)		 RGD PMID:25789628 PMID:29857122 PMID:25392926 RGD:127285679, RGD:127285683, RGD:127345131 NCBI chr 6:124,281,596...124,307,488
Ensembl chr 6:124,281,615...124,307,486 		JBrowse link
G H2-Eb1 histocompatibility 2, class II antigen E beta susceptibility ISO DNA:polymorphism:cds:HLA-DRB1*0401-0411, HLA-DRB1*1001, HLA-DRB1*1101-1105, HLA-DRB1*1201-1202 and HLA-DRB1*1305 (human) RGD PMID:25169964 RGD:40818303 NCBI chr17:34,524,841...34,535,648
Ensembl chr17:34,524,841...34,535,648 		JBrowse link
G Ifng interferon gamma severity ISO protein:increased expression:serum RGD PMID:22613426 RGD:6893374 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797 		JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 severity ISO RGD PMID:25658420 RGD:40400702 NCBI chr 1:40,444,105...40,504,575
Ensembl chr 1:40,468,730...40,504,575 		JBrowse link
G Il2ra interleukin 2 receptor, alpha chain ISO protein:increased expression:T cell RGD PMID:21436245 RGD:5147436 NCBI chr 2:11,647,603...11,698,005
Ensembl chr 2:11,647,618...11,698,004 		JBrowse link
G Il33 interleukin 33 severity ISO RGD PMID:25658420 RGD:40400702 NCBI chr19:29,902,513...29,938,118
Ensembl chr19:29,902,514...29,938,118 		JBrowse link
G Itgb3 integrin beta 3 severity ISO protein:increased expression:platelet RGD PMID:18419255 RGD:6907404 NCBI chr11:104,498,826...104,561,302
Ensembl chr11:104,498,826...104,561,302 		JBrowse link
Korean hemorrhagic fever term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 ISO mRNA:increased expression:lung RGD PMID:17878294 RGD:2325989 NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484 		JBrowse link
G Il2ra interleukin 2 receptor, alpha chain treatment ISO RGD PMID:17878294 RGD:2325989 NCBI chr 2:11,647,603...11,698,005
Ensembl chr 2:11,647,618...11,698,004 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16193
    syndrome 10669
      Hantavirus hemorrhagic fever with renal syndrome 10
        Balkan hemorrhagic fever 0
        Hantavirosis 0
        Korean hemorrhagic fever 2
        nephropathia epidemica 0
        polyomavirus-associated nephropathy 0
Path 2
Term Annotations click to browse term
  disease 16193
    disease by infectious agent 2236
      viral infectious disease 1725
        RNA Virus Infections 1422
          Bunyaviridae Infections 13
            Hantavirus Infections 11
              Hantavirus hemorrhagic fever with renal syndrome 10
                Balkan hemorrhagic fever 0
                Hantavirosis 0
                Korean hemorrhagic fever 2
                nephropathia epidemica 0
                polyomavirus-associated nephropathy 0
paths to the root