RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: Hantavirus hemorrhagic fever with renal syndrome
Accession: DOID:11266
browse the term
Definition: A viral infectious disease that is a hemorrhagic fever, located in kidney, has_material_basis_in Orthohantavirus dobravaense, has_material_basis_in Orthohantavirus hantanense, has_material_basis_in Orthohantavirus puumalaense, has_material_basis_in Orthohantavirus seoulense, which are carried and transmitted by rodents. The infection has symptom headache, has symptom fever, has symptom muscle pains, has symptom facial flush, has symptom petechiae, has symptom proteinuria, and has symptom renal failure. (DO)
Synonyms: exact_synonym: HFRS; Puumala virus nephropathy; Russian hemorrhagic fever; epidemic hemorrhagic fever; epidemic hemorrhagic fevers; hemorrhagic fever with renal syndrome; hemorrhagic nephroso nephritis; hemorrhagic nephroso-nephritides; hemorrhagic nephrosonephritis
primary_id: MESH:D006480
xref: EFO:0007299 ; ICD10CM:A98.5 ; ICD9CM:078.6 ; NCI:C84753
For additional species annotation, visit the
Alliance of Genome Resources .
G
ALB
albumin
severity
IEP
RGD
PMID:14555823
RGD:11035280
NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482
G
APOC3
apolipoprotein C3
disease_progression
IEP
RGD
PMID:20797315
RGD:7207210
NCBI chr11:116,829,907...116,833,072
Ensembl chr11:116,829,706...116,833,072
G
CD163
CD163 molecule
exacerbates
IEP
protein:increased expression:blood plasma (human) protein:increased expression:CD14-positive, CD16-positive monocyte, blood plasma (human) protein:increased expression:CD14-positive monocyte (human)
RGD
PMID:25789628 PMID:25392926 PMID:29857122
RGD:127285679 , RGD:127345131 , RGD:127285683
NCBI chr12:7,470,811...7,503,777
Ensembl chr12:7,470,811...7,503,893
G
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
susceptibility
IAGP
DNA:polymorphism:cds:HLA-DRB1*0401-0411, HLA-DRB1*1001, HLA-DRB1*1101-1105, HLA-DRB1*1201-1202 and HLA-DRB1*1305 (human)
RGD
PMID:25169964
RGD:40818303
NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848
G
HLA-DRB5
major histocompatibility complex, class II, DR beta 5
susceptibility
IAGP
DNA:polymorphism:cds:HLA-DRB5*0101-0201 (human)
RGD
PMID:25169964
RGD:40818303
NCBI chr 6:32,517,353...32,530,287
Ensembl chr 6:32,517,353...32,530,287
G
IFNG
interferon gamma
severity
IEP
protein:increased expression:serum
RGD
PMID:22613426
RGD:6893374
NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
G
IL1RL1
interleukin 1 receptor like 1
severity
IEP
RGD
PMID:25658420
RGD:40400702
NCBI chr 2:102,311,563...102,352,356
Ensembl chr 2:102,311,502...102,352,037
G
IL2RA
interleukin 2 receptor subunit alpha
IEP
protein:increased expression:T cell
RGD
PMID:21436245
RGD:5147436
NCBI chr10:6,010,689...6,062,367
Ensembl chr10:6,010,689...6,062,370
G
IL33
interleukin 33
severity
IEP
RGD
PMID:25658420
RGD:40400702
NCBI chr 9:6,215,149...6,257,983
Ensembl chr 9:6,215,786...6,257,983
G
ITGB3
integrin subunit beta 3
severity
IEP
protein:increased expression:platelet
RGD
PMID:18419255
RGD:6907404
NCBI chr17:47,253,827...47,313,743
Ensembl chr17:47,253,827...47,313,743
G
FOXP3
forkhead box P3
ISO
mRNA:increased expression:lung
RGD
PMID:17878294
RGD:2325989
NCBI chr X:49,250,438...49,264,710
Ensembl chr X:49,250,438...49,264,800
G
IL2RA
interleukin 2 receptor subunit alpha
treatment
ISO
RGD
PMID:17878294
RGD:2325989
NCBI chr10:6,010,689...6,062,367
Ensembl chr10:6,010,689...6,062,370
G
KIR3DS1
killer cell immunoglobulin like receptor, three Ig domains and short cytoplasmic tail 1
susceptibility
IAGP
DNA:deletion (human)
RGD
PMID:23486513
RGD:150340577
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all