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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:spotted fever
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Accession:DOID:11104 term browser browse the term
Definition:A primary bacterial infectious disease that results in infection, located in endothelial cell of artery or located in endothelial cell of vein, has_material_basis_in Rickettsia, which is transmitted by ticks and mites. The infection has symptom fever, has symptom headache, has symptom fatigue, has symptom muscle aches, and has symptom maculopapular or petechial rash. A distinctive eschar (blackened or crusted skin) may develop at the site of a tick bite. (DO)
Synonyms:exact_synonym: spotted fever group rickettsial disease
 xref: EFO:1002047;   GARD:4998;   ICD10CM:A77.9;   ICD9CM:082.0
For additional species annotation, visit the Alliance of Genome Resources.


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boutonneuse fever term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 ISO protein:increased expression:serum RGD PMID:3361150 RGD:11041575 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G Cfb complement factor B ISO protein:increased expression:serum RGD PMID:3361150 RGD:11041575 NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 ISO RGD PMID:14507644 RGD:5135450 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 ISO RGD PMID:14507644 RGD:5135450 NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19099
    disease by infectious agent 2253
      Bacterial Infections and Mycoses 1119
        bacterial infectious disease 825
          primary bacterial infectious disease 197
            spotted fever 4
              African tick-bite fever 0
              Astrakhan spotted fever 0
              Far Eastern spotted fever 0
              Flinders Island spotted fever 0
              Indian tick typhus 0
              Israeli tick typhus 0
              Japanese spotted fever 0
              Queensland tick typhus 0
              Rickettsia parkeri spotted fever 0
              Rocky Mountain spotted fever 0
              Siberian tick typhus 0
              aneruptive fever 0
              boutonneuse fever 4
              rickettsialpox 0
Path 2
Term Annotations click to browse term
  disease 19099
    disease by infectious agent 2253
      Bacterial Infections and Mycoses 1119
        bacterial infectious disease 825
          Gram-Negative Bacterial Infections 200
            Rickettsiaceae Infections 5
              Rickettsia Infections 5
                spotted fever 4
                  African tick-bite fever 0
                  Astrakhan spotted fever 0
                  Far Eastern spotted fever 0
                  Flinders Island spotted fever 0
                  Indian tick typhus 0
                  Israeli tick typhus 0
                  Japanese spotted fever 0
                  Queensland tick typhus 0
                  Rickettsia parkeri spotted fever 0
                  Rocky Mountain spotted fever 0
                  Siberian tick typhus 0
                  aneruptive fever 0
                  boutonneuse fever 4
                  rickettsialpox 0
paths to the root