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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:brucellosis
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Accession:DOID:11077 term browser browse the term
Definition:A primary bacterial infectious disease that is caused by the bacteria of the genus Brucella, when humans come in contact with contaminated animals or animal products or ingestion of infected food products. The disease has_symptom fever, has_symptom sweat, has_symptom headache, has_symptom back pain, has_symptom physical weakness, has_symptom joint pain and has_symptom fatigue. (DO)
Synonyms:exact_synonym: Cyprus fever;   Cyprus fevers;   Malta fever;   Maltese fever;   brucelloses;   pulmonary brucelloses;   pulmonary brucellosis;   rock fever;   rock fevers;   undulant fever
 related_synonym: Gibraltar fever;   Mediterranean fever
 primary_id: MESH:D002006
 xref: EFO:0007185;   GARD:5966;   ICD10CM:A23;   ICD9CM:023;   NCI:C84602
For additional species annotation, visit the Alliance of Genome Resources.


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brucellosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd163 CD163 molecule treatment ISO RGD PMID:32069255 RGD:149735531 NCBI chr 4:158,770,751...158,804,146
Ensembl chr 4:157,085,093...157,117,878 		JBrowse link
G Ifng interferon gamma treatment ISO RGD PMID:27916101 RGD:14974260 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Npc1 NPC intracellular cholesterol transporter 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12183525 NCBI chr18:3,379,482...3,425,100
Ensembl chr18:3,379,482...3,425,049 		JBrowse link
G Pde4a phosphodiesterase 4A IEP mRNA:decreased expression:spleen RGD PMID:17397885 RGD:2302429 NCBI chr 8:27,966,978...28,029,721
Ensembl chr 8:19,703,290...19,751,961 		JBrowse link
G Prdx5 peroxiredoxin 5 ISO mRNA:increased expression:spleen (mouse) RGD PMID:31196623 RGD:41404681 NCBI chr 1:213,529,042...213,532,787
Ensembl chr 1:204,099,826...204,114,268 		JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 ISO RGD PMID:29203515 PMID:30894428 RGD:39128199, RGD:39128234 NCBI chr18:27,606,196...27,612,544
Ensembl chr18:27,332,119...27,338,335 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19142
    disease by infectious agent 2255
      Bacterial Infections and Mycoses 1117
        bacterial infectious disease 823
          Gram-Negative Bacterial Infections 199
            brucellosis 6
              Brucella abortus brucellosis 0
              Brucella canis brucellosis 0
              Brucella melitensis brucellosis 0
              Brucella suis brucellosis 0
paths to the root