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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:hand, foot and mouth disease
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Accession:DOID:10881 term browser browse the term
Definition:A viral infectious disease that results_in infection located_in skin, has_material_basis_in Human coxsackievirus A16 or has_material_basis_in Human enterovirus 71, which are transmitted_by contaminated fomites, and transmitted_by contact with nose and throat secretions, saliva, blister fluid and stool of infected persons. The infection has_symptom fever, has_symptom poor appetite, has_symptom malaise, has_symptom sore throat, has_symptom painful sores in the mouth, and has_symptom skin rash on the palms of the hands and soles of the feet. (DO)
Synonyms:exact_synonym: Hand, Foot, Mouth Disease;   vesicular stomatitis and exanthem
 primary_id: MESH:D006232
 xref: EFO:0007294;   ICD10CM:B08.4;   ICD9CM:074.3;   NCI:C128439
For additional species annotation, visit the Alliance of Genome Resources.



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hand, foot and mouth disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actb actin, beta ISO protein:increased expression:serum RGD PMID:30817906 RGD:36947391 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
JBrowse link
G Ren renin treatment ISO RGD PMID:31638922 RGD:127285374 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18215
    disease by infectious agent 2144
      viral infectious disease 1678
        hand, foot and mouth disease 2
Path 2
Term Annotations click to browse term
  disease 18215
    disease by infectious agent 2144
      viral infectious disease 1678
        RNA Virus Infections 1385
          Picornaviridae Infections 65
            Enterovirus Infections 34
              Coxsackievirus Infections 15
                hand, foot and mouth disease 2
paths to the root