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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:malignant hypertension
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Accession:DOID:10824 term browser browse the term
Definition:A hypertension that is characterized by rapid onset of extremely high blood pressure. (DO)
Synonyms:primary_id: MESH:D006974
 xref: NCI:C3118
For additional species annotation, visit the Alliance of Genome Resources.



show annotations for term's descendants           Sort by:
 
malignant hypertension term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm adrenomedullin ISO protein:increased expression:plasma RGD PMID:15284680 RGD:1625303 NCBI chr 7:110,226,864...110,229,027
Ensembl chr 7:110,226,868...110,229,027
JBrowse link
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) ISO CTD Direct Evidence: marker/mechanism CTD PMID:2493837 PMID:27428043 NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:3142437 NCBI chr19:46,655,604...46,661,439
Ensembl chr19:46,655,604...46,661,611
JBrowse link
G Ren1 renin 1 structural ISO CTD Direct Evidence: marker/mechanism CTD PMID:2493837 NCBI chr 1:133,278,412...133,288,058
Ensembl chr 1:133,278,248...133,288,063
JBrowse link
G Ren2 renin 2 tandem duplication of Ren1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27428043

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15270
    disease of anatomical entity 14918
      cardiovascular system disease 3989
        vascular disease 2846
          hypertension 913
            malignant hypertension 5
              malignant essential hypertension 0
              malignant hypertensive renal disease + 0
              malignant secondary hypertension + 0
Path 2
Term Annotations click to browse term
  disease 15270
    disease of anatomical entity 14918
      cardiovascular system disease 3989
        vascular disease 2846
          artery disease 1810
            hypertension 913
              malignant hypertension 5
                malignant essential hypertension 0
                malignant hypertensive renal disease + 0
                malignant secondary hypertension + 0
paths to the root