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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:malignant hypertension
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Accession:DOID:10824 term browser browse the term
Definition:A hypertension that is characterized by rapid onset of extremely high blood pressure. (DO)
Synonyms:primary_id: MESH:D006974
 xref: NCI:C3118
For additional species annotation, visit the Alliance of Genome Resources.



show annotations for term's descendants           Sort by:
 
malignant hypertension term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADM adrenomedullin ISO protein:increased expression:plasma RGD PMID:15284680 RGD:1625303 NCBI chr21:33,472,197...33,474,472
Ensembl chr21:33,471,623...33,474,495
JBrowse link
G AGT angiotensinogen ISO CTD Direct Evidence: marker/mechanism CTD PMID:2493837 PMID:27428043 NCBI chr 4:8,681,192...8,694,059
Ensembl chr 4:8,683,798...8,693,880
JBrowse link
G CYP17A1 cytochrome P450 family 17 subfamily A member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:3142437 NCBI chr28:15,292,959...15,298,896
Ensembl chr28:15,293,106...15,298,852
JBrowse link
G REN renin ISO CTD Direct Evidence: marker/mechanism CTD PMID:2493837 NCBI chr38:744,540...766,998
Ensembl chr38:744,614...755,012
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14720
    disease of anatomical entity 14396
      cardiovascular system disease 3775
        vascular disease 2690
          hypertension 865
            malignant hypertension 4
              malignant essential hypertension 0
              malignant hypertensive renal disease + 0
              malignant secondary hypertension + 0
Path 2
Term Annotations click to browse term
  disease 14720
    disease of anatomical entity 14396
      cardiovascular system disease 3775
        vascular disease 2690
          artery disease 1725
            hypertension 865
              malignant hypertension 4
                malignant essential hypertension 0
                malignant hypertensive renal disease + 0
                malignant secondary hypertension + 0
paths to the root