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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:malignant hypertension
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Accession:DOID:10824 term browser browse the term
Definition:A hypertension that is characterized by rapid onset of extremely high blood pressure. (DO)
Synonyms:primary_id: MESH:D006974
 xref: NCI:C3118
For additional species annotation, visit the Alliance of Genome Resources.



show annotations for term's descendants           Sort by:
 
malignant hypertension term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADM adrenomedullin ISO protein:increased expression:plasma RGD PMID:15284680 RGD:1625303 NCBI chr11:10,437,712...10,440,053
Ensembl chr11:10,165,418...10,167,842
JBrowse link
G AGT angiotensinogen ISO CTD Direct Evidence: marker/mechanism CTD PMID:2493837 PMID:27428043 NCBI chr 1:206,252,141...206,263,830
Ensembl chr 1:211,279,015...211,291,044
JBrowse link
G CYP17A1 cytochrome P450 family 17 subfamily A member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:3142437 NCBI chr10:99,431,762...99,439,619
Ensembl chr10:102,896,376...102,901,514
JBrowse link
G REN renin ISO CTD Direct Evidence: marker/mechanism CTD PMID:2493837 NCBI chr 1:179,757,653...179,769,530
Ensembl chr 1:184,046,117...184,057,393
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14631
    disease of anatomical entity 0
      cardiovascular system disease 3700
        vascular disease 2624
          hypertension 858
            malignant hypertension 4
              malignant essential hypertension 0
              malignant hypertensive renal disease + 0
              malignant secondary hypertension + 0
Path 2
Term Annotations click to browse term
  disease 14631
    disease of anatomical entity 0
      cardiovascular system disease 3700
        vascular disease 2624
          artery disease 1704
            hypertension 858
              malignant hypertension 4
                malignant essential hypertension 0
                malignant hypertensive renal disease + 0
                malignant secondary hypertension + 0
paths to the root