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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:hypertension
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Accession:DOID:10763 term browser browse the term
Definition:Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
Synonyms:exact_synonym: HTN;   High Blood Pressure;   High Blood Pressures;   hyperpiesia;   vascular hypertensive disorder
 related_synonym: hypertensive disease;   increased aldosterone to renin ratio
 primary_id: MESH:D006973
 xref: ICD9CM:401-405.99;   NCI:C3117
For additional species annotation, visit the Alliance of Genome Resources.

show annotations for term's descendants           Sort by:
 
hypertension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase IDA RGD PMID:1570022 RGD:1598531 NCBI chr10:7,093,406...7,200,439
Ensembl chr10:7,093,405...7,200,499 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17272743 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196 		JBrowse link
G Abcc8 ATP binding cassette subfamily C member 8 ISO associated with obesity;DNA:polymorphism:exon: RGD PMID:11030411 RGD:737749 NCBI chr 1:102,110,708...102,191,287
Ensembl chr 1:102,110,708...102,191,287 		JBrowse link
G Abcc9 ATP binding cassette subfamily C member 9 IEP protein:decreased expression:aorta RGD PMID:15964031, PMID:18471810 RGD:1598644, RGD:2301909 NCBI chr 4:176,806,098...176,928,540
Ensembl chr 4:176,805,431...176,922,424 		JBrowse link
G Abo ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase susceptibility ISO associated with COVID-19; DNA:polymorphism:cds:allele A (human) RGD PMID:32379894 RGD:35668862 NCBI chr 3:4,374,679...4,394,374
Ensembl chr 3:4,374,602...4,394,428 		JBrowse link
G Ace angiotensin I converting enzyme susceptibility
treatment		 ISO
IEP
IMP
IDA		 DNA:polymorphism
CTD Direct Evidence: marker/mechanism
protein:increased activity:lung (rat)		 CTD PMID:15773232 PMID:17473847 PMID:20237592 PMID:27847271, PMID:17283861, PMID:27325568, PMID:16203874, PMID:24342267, PMID:3006710, PMID:15118671, PMID:17392119 RGD:1601114, RGD:40400899, RGD:1581743, RGD:11039415, RGD:8157611, RGD:1331525, RGD:1601113 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822 		JBrowse link
G Ace2 angiotensin I converting enzyme 2 treatment ISO
IEP		 associated with Metabolic Syndrome X (MeSH:D024821)
mRNA, protein:decreased expression:kidney (rat)
CTD Direct Evidence: marker/mechanism|therapeutic
mRNA, protein:decreased expression:aorta		 CTD PMID:12075344 PMID:15833808 PMID:17473847 PMID:18391097 PMID:19221212 PMID:20559404 PMID:21859683, PMID:16459167, PMID:12075344, PMID:20854846, PMID:16788004, PMID:17345786 RGD:1642828, RGD:629626, RGD:9685442, RGD:9685435, RGD:9685433 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016 		JBrowse link
G Acsm3 acyl-CoA synthetase medium-chain family member 3 IAGP RGD PMID:8094726, PMID:8507454 RGD:61050, RGD:634023 NCBI chr 1:189,514,504...189,541,233
Ensembl chr 1:189,514,553...189,541,224 		JBrowse link
G Actc1 actin, alpha, cardiac muscle 1 IEP RGD PMID:16343576 RGD:1598724 NCBI chr 3:105,507,403...105,512,939
Ensembl chr 3:105,507,403...105,512,939 		JBrowse link
G Ada adenosine deaminase IDA RGD PMID:9605386 RGD:1624292 NCBI chr 3:160,115,840...160,139,947
Ensembl chr 3:160,115,842...160,139,947 		JBrowse link
G Adamts16 ADAM metallopeptidase with thrombospondin type 1 motif, 16 IMP RGD PMID:23185005 RGD:9685162 NCBI chr 1:35,067,268...35,200,530
Ensembl chr 1:35,067,490...35,198,939 		JBrowse link
G Adamts16em1Bj ADAM metallopeptidase with thrombospondin type 1 motif, 16; ZFN mutant1,Bj IMP RGD PMID:23185005 RGD:9685162
G Adcy5 adenylate cyclase 5 ISO
IEP		 CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:heart left ventricle		 CTD PMID:12717102, PMID:12717102 RGD:13464134 NCBI chr11:68,695,839...68,842,452
Ensembl chr11:68,695,839...68,842,320 		JBrowse link
G Add1 adducin 1 IAGP
ISO
IDA		 CTD Direct Evidence: marker/mechanism
DNA:polymorphism: :p.G460W (human)		 CTD PMID:15773232 PMID:19199261, PMID:15474463, PMID:8543181, PMID:9149697 RGD:1302895, RGD:631736, RGD:1624953 NCBI chr14:81,367,466...81,426,610
Ensembl chr14:81,367,468...81,426,496 		JBrowse link
G Add2 adducin 2 no_association IDA
ISO		 DNA:SNP: :rs4852706 (human)
DNA:polymorphism		 RGD
GAD		 PMID:2059221, PMID:24652215, PMID:15118671, PMID:16497648 RGD:631712, RGD:10047131, RGD:1331525, RGD:1625293 NCBI chr 4:117,691,294...117,887,556
Ensembl chr 4:117,743,710...117,882,464 		JBrowse link
G Add3 adducin 3 IDA RGD PMID:12364392 RGD:704369 NCBI chr 1:273,854,195...273,961,982
Ensembl chr 1:273,854,248...273,961,982 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO CTD Direct Evidence: marker/mechanism CTD PMID:12860835 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488 		JBrowse link
G Adm adrenomedullin IEP
ISO		 mRNA, protein:increased expression:myocardium, aorta
protein:increased expression:plasma		 RGD PMID:16450076, PMID:16625237 RGD:1625300, RGD:1625298 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259 		JBrowse link
G Adora1 adenosine A1 receptor treatment
no_association		 IMP
IDA
ISO		 associated with diabetes mellitus, experimental RGD PMID:8998253, PMID:9597368, PMID:15257174 RGD:1625366, RGD:1625365, RGD:1625367 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852 		JBrowse link
G Adora2a adenosine A2a receptor no_association ISO RGD
GAD		 PMID:15257174, PMID:15118671 RGD:1625367, RGD:1331525 NCBI chr20:14,265,251...14,282,873
Ensembl chr20:14,265,252...14,282,873 		JBrowse link
G Adra1a adrenoceptor alpha 1A IEP
ISO		 mRNA:decreased expression:aorta RGD PMID:16371063, PMID:19011682 RGD:1625770, RGD:5688340 NCBI chr15:43,296,997...43,398,314
Ensembl chr15:43,298,794...43,392,451 		JBrowse link
G Adra1b adrenoceptor alpha 1B ISO RGD PMID:16095979 RGD:1625771 NCBI chr10:29,392,762...29,450,644
Ensembl chr10:29,392,762...29,450,644 		JBrowse link
G Adra2a adrenoceptor alpha 2A no_association ISO
IEP		 DNA:polymorphism
CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:adrenal gland medulla 		CTD PMID:10694191, PMID:16636200, PMID:20691504 RGD:1625183, RGD:6480490 NCBI chr 1:274,766,283...274,769,083
Ensembl chr 1:274,766,283...274,769,081 		JBrowse link
G Adra2b adrenoceptor alpha 2B ISO
IMP		 DNA:polymorphism (human) RGD PMID:18953403, PMID:17070424 RGD:2313541, RGD:2313548 NCBI chr 3:119,805,941...119,809,987
Ensembl chr 3:119,805,941...119,809,987 		JBrowse link
G Adrb1 adrenoceptor beta 1 IEP
ISO		 protein:increased expression:aorta
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Type 2;		 CTD PMID:9260993 PMID:10673262, PMID:19060223, PMID:20398560 RGD:5129127, RGD:7241549 NCBI chr 1:277,537,585...277,538,985
Ensembl chr 1:277,537,585...277,538,985 		JBrowse link
G Adrb2 adrenoceptor beta 2 no_association
susceptibility		 ISO
IEP		 DNA:polymorphisms: :p.R16G, p.Q27E
DNA:polymorphisms: :pG16R, p.Q27E, p.T164I (human)
associated with Kidney Failure, Chronic; DNA:SNP:cds:p.R16G (human)
DNA:polymorphisms: :46A>G, 79C>G (human)		 RGD
GAD		 PMID:17221209, PMID:16041242, PMID:15118671, PMID:2471888, PMID:20484896, PMID:20739939, PMID:16685203 RGD:1601119, RGD:1578728, RGD:1331525, RGD:7175287, RGD:7175066, RGD:4144883, RGD:1601123 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834 		JBrowse link
G Adrb3 adrenoceptor beta 3 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism: :p.W64R (human) RGD PMID:10981554 RGD:2313166 NCBI chr16:69,003,541...69,006,632
Ensembl chr16:69,003,868...69,006,632 		JBrowse link
G Ager advanced glycosylation end product-specific receptor IEP
ISO		 protein:increased expression:kidney
CTD Direct Evidence: marker/mechanism		 CTD PMID:32147540, PMID:19018797 RGD:2325653 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079 		JBrowse link
G Agt angiotensinogen treatment
no_association
susceptibility		 IEP
ISO
IDA
IMP		 protein:increased expression:plasma, urine
CTD Direct Evidence: marker/mechanism|therapeutic
DNA:polymorphisms: :p.T174M, p.M235T (human)
DNA:polymorphisms: :-6G>A, p.M235T, p.T174M
DNA:polymorphism: :p.M235T
DNA:polymorphism:promoter:-20C>A (human)
DNA:polymorphism: :p.M268T (human)		 CTD PMID:43064 PMID:1394429 PMID:1432030 PMID:1849535 PMID:1860718 PMID:1875449 PMID:2831029 PMID:2835134 PMID:3158602 PMID:6742791 PMID:7323490 PMID:8021468 PMID:8109997 PMID:8505092 PMID:9024144 PMID:9260993 PMID:10400907 PMID:10526905 PMID:11459117 PMID:11501062 PMID:12084390 PMID:12121858 PMID:12414515 PMID:12600921 PMID:12676074 PMID:14751847 PMID:15243307 PMID:15302986 PMID:15699457 PMID:15833808 PMID:15851630 PMID:16618834 PMID:16788141 PMID:16868307 PMID:17272743 PMID:17537837 PMID:17989111 PMID:18420994 PMID:18679781 PMID:18768397 PMID:18785976 PMID:18847324 PMID:19109942 PMID:19133994 PMID:19373235 PMID:19770776 PMID:19858406 PMID:20231528 PMID:20429690 PMID:20713914 PMID:20811386 PMID:20837116 PMID:20937366 PMID:21289285 PMID:21393355 PMID:21420289 PMID:21501650 PMID:22083158 PMID:22214961 PMID:22452651 PMID:22753205 PMID:22982863 PMID:24342267 PMID:24347665 PMID:24386282 PMID:24935938 PMID:24965170 PMID:25139994 PMID:25259750 PMID:25398788 PMID:25874449 PMID:26564064 PMID:26648693 PMID:26781276 PMID:27225954 PMID:27678262 PMID:27798352 PMID:27889505 PMID:29706566 PMID:30354818 PMID:31016362 PMID:31098697 PMID:31786979, PMID:21346625, PMID:24342267, PMID:21865264, PMID:19932924, PMID:9622148, PMID:19779471, PMID:15118671, PMID:1394429, PMID:12468106, PMID:16514903, PMID:17334527, PMID:16739866, PMID:17161775, PMID:21312059 RGD:5129176, RGD:11039415, RGD:8549470, RGD:8549469, RGD:8549458, RGD:8548902, RGD:1331525, RGD:1300393, RGD:1358275, RGD:1601143, RGD:1601130, RGD:1601141, RGD:1601139, RGD:5129166 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a no_association
susceptibility		 IMP
ISO
IEP		 associated with Sleep Apnea Syndromes
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:aortic endothelial cell
DNA:polymorphism:3' utr:1166A>C
DNA:polymorphism:3' utr:g.1166A>C		 CTD PMID:8952600 PMID:19047579 PMID:23603059 PMID:27292124, PMID:21040717, PMID:9622148, PMID:15118671, PMID:8181542, PMID:9456365, PMID:16519598, PMID:21346625 RGD:5129169, RGD:8549458, RGD:1331525, RGD:5147456, RGD:1601152, RGD:1601148, RGD:5129176 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077 		JBrowse link
G Agtr1b angiotensin II receptor, type 1b IEP
ISO		 CTD Direct Evidence: marker/mechanism CTD PMID:22728133 PMID:27847271, PMID:10994756 RGD:1598885 NCBI chr 2:105,149,020...105,224,335
Ensembl chr 2:105,149,020...105,224,295 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 IMP
ISO
IEP		 associated with Sleep Apnea Syndromes
CTD Direct Evidence: marker/mechanism
mRNA, protein:decreased expression:kidney		 CTD PMID:15710752, PMID:21040717, PMID:11924718, PMID:19680135 RGD:5129169, RGD:6903865, RGD:6903372 NCBI chr  X:119,389,480...119,393,845
Ensembl chr  X:119,390,013...119,393,842 		JBrowse link
G Agtrap angiotensin II receptor-associated protein IEP protein:increased expression:kidney RGD PMID:18725581 RGD:2314351 NCBI chr 5:164,888,069...164,898,387
Ensembl chr 5:164,886,813...164,898,420 		JBrowse link
G Ahcy adenosylhomocysteinase ISO associated with hyperhomocysteinemia RGD PMID:16815886 RGD:1601153 NCBI chr 3:150,587,833...150,603,057
Ensembl chr 3:150,587,833...150,603,082 		JBrowse link
G Ahr aryl hydrocarbon receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21115475 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464 		JBrowse link
G Aif1 allograft inflammatory factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:32147540 NCBI chr20:5,161,350...5,167,176
Ensembl chr20:5,161,333...5,166,448 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 IDA protein:increased serine phosphorylation:kidney RGD PMID:23323219 RGD:10041025 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258 		JBrowse link
G Akt2 AKT serine/threonine kinase 2 IEP mRNA:increased expression:cerebral cortex (rat) RGD PMID:12902546 RGD:2313350 NCBI chr 1:84,400,939...84,451,223
Ensembl chr 1:84,411,726...84,450,162 		JBrowse link
G Alad aminolevulinate dehydratase no_association ISO DNA:polymorphism
CTD Direct Evidence: marker/mechanism		 CTD PMID:20123609, PMID:11335187 RGD:1601156 NCBI chr 5:78,368,867...78,379,206
Ensembl chr 5:78,368,867...78,379,346 		JBrowse link
G Alb albumin ISO CTD Direct Evidence: therapeutic CTD PMID:2526952 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member susceptibility
no_association		 ISO RGD PMID:11510748, PMID:12484509 RGD:1601164, RGD:1601163 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752 		JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type IEP mRNA:decreased expression:medulla oblongata RGD PMID:16445702 RGD:5509789 NCBI chr10:56,851,734...56,864,049
Ensembl chr10:56,851,734...56,864,005 		JBrowse link
G Alox15 arachidonate 15-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:22467300 NCBI chr10:56,953,692...56,962,145
Ensembl chr10:56,953,691...56,962,161 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase IDA RGD PMID:16331105 RGD:1626151 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303 		JBrowse link
G Angpt1 angiopoietin 1 ISO protein:increased expression:plasma, platelet RGD PMID:16942942, PMID:18285514 RGD:1626157, RGD:2316068 NCBI chr 7:81,338,327...81,592,459
Ensembl chr 7:81,342,280...81,592,206 		JBrowse link
G Anxa1 annexin A1 IEP
ISO		 protein:altered localization:vascular associated smooth muscle cell
CTD Direct Evidence: marker/mechanism		 CTD PMID:22228705, PMID:16109804 RGD:1599668 NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012 		JBrowse link
G Aoc1 amine oxidase, copper containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:6218830 NCBI chr 4:78,496,043...78,515,582
Ensembl chr 4:78,496,043...78,515,584 		JBrowse link
G Aoc3 amine oxidase, copper containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23154672 NCBI chr10:89,251,370...89,259,313
Ensembl chr10:89,251,370...89,259,313 		JBrowse link
G Apln apelin IEP mRNA:decreased expression:aorta, heart RGD PMID:15664402 RGD:1626176 NCBI chr  X:134,856,719...134,866,210
Ensembl chr  X:134,856,726...134,866,210 		JBrowse link
G Apoa1 apolipoprotein A1 IEP
ISO		 CTD Direct Evidence: marker/mechanism CTD PMID:18224302, PMID:23401751 RGD:7241867 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875 		JBrowse link
G Apob apolipoprotein B ISO GAD PMID:15118671 RGD:1331525 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997 		JBrowse link
G Apoe apolipoprotein E onset ISO
IEP		 CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:multiple (rat)		 CTD PMID:20720404 PMID:22228705, PMID:15118671, PMID:20585107 RGD:1331525, RGD:6904214 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057 		JBrowse link
G App amyloid beta precursor protein IEP RGD PMID:29713228 RGD:13703136 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858 		JBrowse link
G Aqp1 aquaporin 1 IEP
ISO		 CTD Direct Evidence: marker/mechanism CTD PMID:22228705, PMID:20156423 RGD:5148031 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360 		JBrowse link
G Aqp2 aquaporin 2 IEP protein:decreased expression:kidney medulla
protein:increased expression:kidney medulla		 RGD PMID:16788141, PMID:16582573 RGD:1601242, RGD:1601243 NCBI chr 7:141,237,802...141,242,837
Ensembl chr 7:141,237,768...141,245,165 		JBrowse link
G Aqp4 aquaporin 4 IEP RGD PMID:20156423 RGD:5148031 NCBI chr18:6,766,009...6,782,757
Ensembl chr18:6,765,945...6,782,996 		JBrowse link
G Ar androgen receptor treatment IDA
ISO
IMP		 CTD Direct Evidence: marker/mechanism CTD PMID:10523385, PMID:15746697, PMID:12397037 RGD:1601245, RGD:10043316 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026 		JBrowse link
G Arg1 arginase 1 IMP
IEP		 mRNA:increased expression:aorta (rat) RGD PMID:18475148, PMID:17223136 RGD:4142834, RGD:1626296 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863 		JBrowse link
G Arg2 arginase 2 IMP
IEP		 mRNA:increased expression:lung
mRNA:increased expression:aorta (rat)		 RGD PMID:18475148, PMID:20039818, PMID:17223136 RGD:4142834, RGD:4143278, RGD:1626296 NCBI chr 6:102,311,097...102,338,406
Ensembl chr 6:102,311,116...102,338,520 		JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha IEP mRNA:decreased expression:urinary bladder
protein:decreased expression:cortical collecting duct 		RGD PMID:19689474, PMID:25164814 RGD:9684972, RGD:9684979 NCBI chr10:109,754,012...109,757,506
Ensembl chr10:109,754,004...109,757,550 		JBrowse link
G Arid1b AT-rich interaction domain 1B treatment IEP RGD PMID:17489020 RGD:9587762 NCBI chr 1:45,923,119...46,232,301
Ensembl chr 1:45,923,222...46,234,874 		JBrowse link
G Arntl2 aryl hydrocarbon receptor nuclear translocator-like 2 ISO DNA:SNPs: :rs6486121, rs3789327, rs969485(human) RGD PMID:17728404 RGD:2314371 NCBI chr 4:181,103,774...181,158,415
Ensembl chr 4:181,103,774...181,214,994 		JBrowse link
G Arrb2 arrestin, beta 2 IEP protein:decreased expression:rostral ventrolateral medulla RGD PMID:27861247 RGD:13506896 NCBI chr10:57,040,252...57,048,045
Ensembl chr10:57,040,267...57,048,134 		JBrowse link
G Atf2 activating transcription factor 2 IDA RGD PMID:11358932 RGD:10047414 NCBI chr 3:60,721,137...60,795,951
Ensembl chr 3:60,721,135...60,795,951 		JBrowse link
G Atg7 autophagy related 7 IEP protein:increased expression:skeletal muscle RGD PMID:24119246 RGD:11557985 NCBI chr 4:146,570,113...146,777,093
Ensembl chr 4:146,598,413...146,777,124 		JBrowse link
G Atox1 antioxidant 1 copper chaperone ISO CTD Direct Evidence: therapeutic CTD PMID:22753205 NCBI chr10:40,790,850...40,805,886
Ensembl chr10:40,790,845...40,805,941 		JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 IAGP
ISO		 CTD Direct Evidence: marker/mechanism CTD PMID:23416519, PMID:8082931 RGD:1579862 NCBI chr 2:204,003,742...204,032,023
Ensembl chr 2:204,003,742...204,032,023 		JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 susceptibility IEP
ISO		 protein:decreased expression:adrenal gland cortex zone
CTD Direct Evidence: marker/mechanism		 CTD PMID:16166162 PMID:16243970, PMID:11768735, PMID:11257061, PMID:16243970 RGD:1601253, RGD:1601254, RGD:1601251 NCBI chr13:90,651,682...90,676,629
Ensembl chr13:90,651,686...90,676,629 		JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 IEP RGD PMID:11208768 RGD:68726 NCBI chr10:59,528,849...59,560,440
Ensembl chr10:59,529,785...59,560,433 		JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 IEP
ISO		 mRNA:increased expression:vascular associated smooth muscle cell
CTD Direct Evidence: marker/mechanism		 CTD PMID:19430479, PMID:20137670 RGD:2317726 NCBI chr 7:41,114,606...41,223,138
Ensembl chr 7:41,114,697...41,220,579 		JBrowse link
G Atp2b3 ATPase plasma membrane Ca2+ transporting 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23416519 NCBI chr  X:157,236,400...157,312,028
Ensembl chr  X:157,239,306...157,312,028 		JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha IEP protein:decreased expression:heart left ventricle (rat) RGD PMID:24388463 RGD:7800726 NCBI chr18:74,156,553...74,164,490
Ensembl chr18:74,156,553...74,164,495 		JBrowse link
G Atp6ap2 ATPase H+ transporting accessory protein 2 IEP RGD PMID:21321306 RGD:5132599 NCBI chr  X:11,137,889...11,164,854
Ensembl chr  X:11,136,939...11,164,915 		JBrowse link
G Avp arginine vasopressin IEP
ISO		 protein:increased expression:carotid artery
CTD Direct Evidence: marker/mechanism
protein:increased expression:plasma		 CTD PMID:1663982 PMID:3346065 PMID:4040330 PMID:6367368 PMID:19133994, PMID:12623976, PMID:16582573 RGD:1601305, RGD:1601243 NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460 		JBrowse link
G Avpr1a arginine vasopressin receptor 1A IEP
ISO		 mRNA, protein:increased expression:paraventricular hypothalamic nucleus
mRNA, protein:increased expression:kidney, arteriole
DNA:SNP		 RGD PMID:15475662, PMID:15657301, PMID:17653244 RGD:2300330, RGD:2300322, RGD:2300319 NCBI chr 7:67,341,366...67,345,290
Ensembl chr 7:67,341,080...67,345,308 		JBrowse link
G Avpr2 arginine vasopressin receptor 2 severity IDA RGD PMID:12072411 RGD:1298694 NCBI chr  X:156,889,006...156,892,707
Ensembl chr  X:156,889,410...156,891,213 		JBrowse link
G B2m beta-2 microglobulin ISO protein:increased expression:serum RGD PMID:15957539 RGD:1601306 NCBI chr 3:114,087,287...114,093,311
Ensembl chr 3:114,087,287...114,093,309 		JBrowse link
G Bad BCL2-associated agonist of cell death treatment IEP RGD PMID:20065158 RGD:10053702 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment IEP RGD PMID:20065158 RGD:10053702 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207 		JBrowse link
G Bche butyrylcholinesterase ISO RGD PMID:12387587 RGD:1601322 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395 		JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment IEP
ISO		 CTD Direct Evidence: marker/mechanism CTD PMID:10075388, PMID:20065158 RGD:10053702 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374 		JBrowse link
G Bdkrb1 bradykinin receptor B1 IMP
IEP
ISO		 RGD PMID:17988733, PMID:12025958, PMID:15643125 RGD:5129214, RGD:704378, RGD:1625732 NCBI chr 6:129,437,423...129,441,553
Ensembl chr 6:129,438,158...129,440,574 		JBrowse link
G Bdkrb2 bradykinin receptor B2 IEP
ISO		 protein:increased expression:spinal cord
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:hypothalamus
DNA:SNP:promoter:-58T>C (human)		 CTD PMID:10614985, PMID:11934804, PMID:15118671, PMID:12025958, PMID:10904024 RGD:4890455, RGD:1331525, RGD:704378, RGD:4891034 NCBI chr 6:129,399,468...129,429,676
Ensembl chr 6:129,399,468...129,429,676 		JBrowse link
G Becn1 beclin 1 IEP protein:increased expression:brain RGD PMID:23499735 RGD:11561939 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297 		JBrowse link
G Brca1 BRCA1, DNA repair associated IEP RGD PMID:24239235 RGD:8693672 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681 		JBrowse link
G Brs3 bombesin receptor subtype 3 ISO RGD PMID:9367152 RGD:734661 NCBI chr  X:159,484,953...159,510,944
Ensembl chr  X:159,505,344...159,511,021 		JBrowse link
G C3 complement C3 IEP RGD PMID:22416803 RGD:11040890 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167 		JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C ISO CTD Direct Evidence: marker/mechanism CTD PMID:22949532 NCBI chr 4:150,635,808...151,270,790
Ensembl chr 4:150,641,066...150,829,913 		JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22949532 NCBI chr 4:15,706,974...16,130,848
Ensembl chr 4:15,710,417...16,130,848 		JBrowse link
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 susceptibility ISO DNA:SNP: :rs4373814(human) RGD PMID:24338417 RGD:13513987 NCBI chr17:81,673,862...82,019,219
Ensembl chr17:81,798,756...82,017,682 		JBrowse link
G Calca calcitonin-related polypeptide alpha ISO CTD Direct Evidence: therapeutic CTD PMID:1849535 PMID:9887042 NCBI chr 1:184,184,018...184,188,922
Ensembl chr 1:184,184,020...184,188,911 		JBrowse link
G Casp3 caspase 3 treatment IDA
IEP		 RGD PMID:20065158, PMID:27929425 RGD:10053702, RGD:13782308 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204 		JBrowse link
G Casp8 caspase 8 IEP RGD PMID:27929425 RGD:13782308 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106 		JBrowse link
G Casp9 caspase 9 IEP RGD PMID:27929425 RGD:13782308 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778 		JBrowse link
G Cat catalase IEP
ISO		 CTD Direct Evidence: marker/mechanism CTD PMID:11479740 PMID:20667508 PMID:21593737 PMID:22228705, PMID:16716903 RGD:1580833 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058 		JBrowse link
G Cav1 caveolin 1 IEP
ISO		 protein:increased expression:artery smooth muscle, blood vessel endothelial cell
CTD Direct Evidence: marker/mechanism		 CTD PMID:1798635, PMID:17986358 RGD:2289116 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200 		JBrowse link
G Cbs cystathionine beta synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:18224302 NCBI chr20:10,361,987...10,386,663
Ensembl chr20:10,361,988...10,386,751 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 treatment IEP
ISO
IDA		 protein:increased expression:urine
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Non-Insulin-Dependent;mRNA, protein:increased expression:kidney cortex, urine		 CTD PMID:20667508 PMID:27292124, PMID:17989143, PMID:17922026, PMID:18459944 RGD:2307054, RGD:8549771, RGD:2307029 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870 		JBrowse link
G Ccl28 C-C motif chemokine ligand 28 no_association IEP mRNA, protein:decreased expression:kidney (rat)
protein:increased expression:kidney (rat)		 RGD PMID:19829664, PMID:16840655 RGD:4892132, RGD:2298761 NCBI chr 2:52,379,341...52,403,979
Ensembl chr 2:52,379,341...52,404,246 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:serum RGD PMID:15668187 RGD:2307105 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315 		JBrowse link
G Ccn2 cellular communication network factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16685210 NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773 		JBrowse link
G Ccne1 cyclin E1 IEP protein:increased expression:vascular associated smooth muscle cell RGD PMID:12847112 RGD:2289296 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980 		JBrowse link
G Ccr5 C-C motif chemokine receptor 5 IEP
ISO		 mRNA:increased expression:aorta (rat)
DNA:frameshift mutation:cds:p.S185_T195del rs333 (human)		 RGD PMID:20044442, PMID:12680626 RGD:4890416, RGD:1581182 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614 		JBrowse link
G Cd14 CD14 molecule ISO associated with Glomerulonephritis, IGA; DNA:polymorphism: :-159C>T (human) RGD PMID:22072187 RGD:7204129 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153 		JBrowse link
G Cd36 CD36 molecule IEP
ISO		 CTD Direct Evidence: marker/mechanism CTD PMID:18587397, PMID:18587397 RGD:2300254 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749 		JBrowse link
G Cd82 Cd82 molecule IEP mRNA:increased expression:thymus RGD PMID:10321446 RGD:2289422 NCBI chr 3:82,324,344...82,368,846
Ensembl chr 3:82,324,354...82,368,357 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A IEP protein:increased expression:kidney RGD PMID:18504326 RGD:2316082 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175 		JBrowse link
G Cdo1 cysteine dioxygenase type 1 IEP protein:decreased expression:brain RGD PMID:6726227 RGD:2301363 NCBI chr18:40,702,027...40,716,901
Ensembl chr18:40,701,984...40,716,686 		JBrowse link
G Cela2a chymotrypsin like elastase 2A ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: High blood pressure		 CTD
ClinVar		 PMID:21602471 PMID:31358993 NCBI chr 5:160,374,031...160,383,782
Ensembl chr 5:160,374,031...160,383,782 		JBrowse link
G Chga chromogranin A no_association ISO
IEP		 protein:creased expression:adrenal gland
mRNA, protein:increased expression:adrenal gland medulla, plasma
DNA:polymorphisms:promoter		 RGD PMID:21061160, PMID:10803489, PMID:10803489, PMID:20113265, PMID:20729505 RGD:6906897, RGD:6907055, RGD:6907055, RGD:6906902, RGD:6906900 NCBI chr 6:126,434,226...126,445,569
Ensembl chr 6:126,434,226...126,445,568 		JBrowse link
G Chi3l1 chitinase 3 like 1 IEP mRNA:increased expression:brainstem, solitary tract nucleus (rat) RGD PMID:18703386 RGD:4892597 NCBI chr13:51,022,844...51,030,797
Ensembl chr13:51,022,681...51,030,802 		JBrowse link
G Chst12 carbohydrate sulfotransferase 12 IEP mRNA:decreased expression:renal cortex and medulla (rat) RGD PMID:25001272 RGD:8693701 NCBI chr12:16,199,975...16,218,404
Ensembl chr12:16,200,019...16,201,632 		JBrowse link
G Clcnka chloride voltage-gated channel Ka ISO CTD Direct Evidence: marker/mechanism CTD PMID:18480177 NCBI chr 5:159,931,497...159,946,483
Ensembl chr 5:159,931,511...159,946,446 		JBrowse link
G Clcnkb chloride voltage-gated channel Kb no_association ISO DNA:polymorphism:T481S RGD PMID:15148291, PMID:16003175 RGD:1600684, RGD:1600683 NCBI chr 5:159,950,384...159,973,576
Ensembl chr 5:159,950,392...159,962,676 		JBrowse link
G Cldn16 claudin 16 IDA Protein:decreased serine phosphorylation:kidney RGD PMID:16959063 RGD:1599616 NCBI chr11:77,683,942...77,703,232
Ensembl chr11:77,681,794...77,703,255 		JBrowse link
G Clock clock circadian regulator IEP mRNA:altered expression:gastrocnemius muscle (rat) RGD PMID:22076133 RGD:9686076 NCBI chr14:34,418,226...34,502,218
Ensembl chr14:34,446,616...34,502,218 		JBrowse link
G Clu clusterin ISO DNA:SNP:exon:866C>T (human) RGD PMID:15925890 RGD:1581195 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857 		JBrowse link
G Cma1 chymase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14620933 NCBI chr15:34,601,037...34,603,819
Ensembl chr15:34,601,037...34,603,819 		JBrowse link
G Cnr1 cannabinoid receptor 1 IMP RGD PMID:19133994 RGD:2314680 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056 		JBrowse link
G Col1a1 collagen type I alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:11682445 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789 		JBrowse link
G Col3a1 collagen type III alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:11682445 NCBI chr 9:52,023,295...52,059,221
Ensembl chr 9:52,023,295...52,059,217 		JBrowse link
G Col4a4 collagen type IV alpha 4 chain ISO ClinVar Annotator: match by term: Hypertension
ClinVar Annotator: match by term: High blood pressure		 ClinVar PMID:24033266 PMID:25741868 NCBI chr 9:88,314,763...88,357,183
Ensembl chr 9:88,232,455...88,357,182 		JBrowse link
G Col4a5 collagen type IV alpha 5 chain ISO ClinVar Annotator: match by term: Hypertension ClinVar PMID:9848783 PMID:11223851 PMID:17396119 PMID:19728970 PMID:19965530 PMID:20378821 PMID:21332469 PMID:24470729 PMID:25741868 PMID:26467025 PMID:26809805 PMID:26934356 PMID:28492532 PMID:28844315 PMID:29854973 NCBI chr  X:112,769,595...112,983,720
Ensembl chr  X:112,769,645...112,983,685 		JBrowse link
G Comt catechol-O-methyltransferase susceptibility IEP
IDA
ISO		 protein:increased expression:cerebral cortex
DNA:polymorphism: :-1187G>C, 186C>T 		RGD PMID:17978496, PMID:17510509, PMID:17143180, PMID:14714585 RGD:2289729, RGD:8662344, RGD:2289742, RGD:2289787 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622 		JBrowse link
G Corin corin, serine peptidase ISO RGD PMID:17485366, PMID:16216958 RGD:1626338, RGD:1581219 NCBI chr14:38,247,379...38,474,931
Ensembl chr14:38,247,791...38,473,648 		JBrowse link
G Cox5b cytochrome c oxidase subunit 5B IEP protein:decreased expression:heart left ventricle RGD PMID:16132109 RGD:2301377 NCBI chr 9:43,259,706...43,262,039
Ensembl chr 9:43,259,709...43,262,040 		JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 IEP protein:decreased expression:liver, mitochondrion RGD PMID:19135993 RGD:2303405 NCBI chr 9:74,113,437...74,236,274
Ensembl chr 9:74,124,016...74,236,274 		JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 IDA corticotropin releasing hormone-induced RGD PMID:11036160 RGD:1581302 NCBI chr10:92,191,473...92,233,662
Ensembl chr10:92,191,718...92,232,645 		JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10742107 NCBI chr 4:85,286,371...85,329,374
Ensembl chr 4:85,286,372...85,329,362 		JBrowse link
G Crp C-reactive protein IEP
ISO		 protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism
protein:increased expression:serum:		 CTD PMID:14620923 PMID:16680063 PMID:19770776 PMID:20667508, PMID:19905982, PMID:19056836, PMID:6720266 RGD:5131461, RGD:9586008, RGD:9491754 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713 		JBrowse link
G Ctf1 cardiotrophin 1 ISO
IEP		 protein:increased expression:plasma
mRNA:increased expression:cardiac ventricle		 RGD PMID:15716706, PMID:8604995 RGD:1626411, RGD:69823 NCBI chr 1:199,162,319...199,168,296
Ensembl chr 1:199,163,086...199,168,296 		JBrowse link
G Ctsc cathepsin C IEP RGD PMID:657443 RGD:1599651 NCBI chr 1:151,918,514...151,949,979
Ensembl chr 1:151,918,571...151,949,983 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22352330 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391 		JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27678262 NCBI chr 9:81,427,275...81,435,065
Ensembl chr 9:81,427,730...81,434,102 		JBrowse link
G Cyba cytochrome b-245 alpha chain IDA
ISO
IEP		 CTD Direct Evidence: marker/mechanism
protein:increased expression:kidney cortex		 CTD PMID:16685210 PMID:17324946 PMID:20505675 PMID:32147540, PMID:17109653, PMID:12729892, PMID:20018820 RGD:4775206, RGD:1580276, RGD:2317853 NCBI chr19:55,249,634...55,257,824
Ensembl chr19:55,249,616...55,257,876 		JBrowse link
G Cybb cytochrome b-245 beta chain IEP
ISO		 Protein:increased expression:brain
CTD Direct Evidence: marker/mechanism		 CTD PMID:16685210 PMID:21593737 PMID:27659729 PMID:27847271 PMID:32147540 PMID:32165127, PMID:12472782 RGD:1599685 NCBI chr  X:14,578,330...14,610,049
Ensembl chr  X:14,578,264...14,612,547 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 IEP mRNA:increased expression:hypothalamus RGD PMID:16116051 RGD:1599701 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893 		JBrowse link
G Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 IEP
IAGP		 mRNA:decreased expression:hypothalamus, cerebellum, cortex (rat) RGD PMID:19837774, PMID:7981756 RGD:4891156, RGD:69709
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 ISO
IMP
IEP		 DNA:transition:5' utr:-344C>T (human)
mRNA:increased expression:brainstem, hippocampus, cortex (rat)		 RGD PMID:10024332, PMID:18495825, PMID:19837774 RGD:4891152, RGD:2307304, RGD:4891156 NCBI chr 7:116,248,759...116,255,205
Ensembl chr 7:116,156,219...116,255,167 		JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 ISO ClinVar Annotator: match by term: Aldosterone to renin ratio, increased ClinVar PMID:12213905 PMID:12788845 PMID:17003099 NCBI chr 7:116,155,928...116,161,781
Ensembl chr 7:116,156,219...116,255,167 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 IEP mRNA:decreased expression:ovary (rat) RGD PMID:19228890 RGD:4761326 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20634294 PMID:22995157, PMID:20634294 RGD:7257731 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147 		JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 ISO
IEP		 RGD PMID:19669737, PMID:18829737 RGD:6903909, RGD:6903915 NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434 		JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 susceptibility ISO DNA:SNP RGD PMID:17286575, PMID:20501636 RGD:1625379, RGD:7243136 NCBI chr 5:119,546,458...119,564,843
Ensembl chr 5:119,546,461...119,564,846 		JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 ISO
IEP		 mRNA:decreased expression:kidney cortex RGD PMID:16144986, PMID:16339392, PMID:18952718 RGD:1625567, RGD:2303383, RGD:2303381 NCBI chr 5:134,492,734...134,507,158
Ensembl chr 5:134,492,756...134,507,154 		JBrowse link
G Cyp4a8 cytochrome P450, family 4, subfamily a, polypeptide 8 IEP mRNA:decreased expression:kidney cortex RGD PMID:18952718, PMID:16339392 RGD:2303381, RGD:2303383 NCBI chr 5:133,978,953...134,008,255
Ensembl chr 5:133,978,954...134,008,255 		JBrowse link
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 IEP mRNA:increased expression:kidney RGD PMID:16182239 RGD:2301709 NCBI chr 7:15,179,472...15,191,113
Ensembl chr 7:15,179,467...15,190,796 		JBrowse link
G Dars2 aspartyl-tRNA synthetase 2 (mitochondrial) ISO ClinVar Annotator: match by term: High blood pressure ClinVar PMID:17384640 PMID:19592391 PMID:22843165 PMID:23065766 PMID:23652419 PMID:24005482 PMID:24407472 PMID:25741868 NCBI chr13:78,857,638...78,885,464
Ensembl chr13:78,857,638...78,885,464 		JBrowse link
G Dbh dopamine beta-hydroxylase resistance IEP
ISO		 mRNA:increased expression:heart, adrenal gland (rat)
DNA:polymorphism:5' utr:g.-2073C>T rs1989787 (human)		 RGD PMID:20596792, PMID:20814407 RGD:5129234, RGD:5129211 NCBI chr 3:5,709,236...5,731,895
Ensembl chr 3:5,709,236...5,731,898 		JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 susceptibility ISO RGD PMID:16444868 RGD:1625582 NCBI chr 2:251,634,368...251,766,009
Ensembl chr 2:251,634,431...251,766,014 		JBrowse link
G Dio2 iodothyronine deiodinase 2 susceptibility ISO RGD PMID:17224473 RGD:1626437 NCBI chr 6:114,475,156...114,489,443
Ensembl chr 6:114,476,142...114,476,723 		JBrowse link
G Drd1 dopamine receptor D1 ISO RGD PMID:10948075, PMID:8636408 RGD:1580869, RGD:1300303 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541 		JBrowse link
G Drd2 dopamine receptor D2 ISO DNA:polymorphism
CTD Direct Evidence: marker/mechanism		 CTD PMID:11566895, PMID:15939106, PMID:11494094 RGD:1600905, RGD:1580874 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642 		JBrowse link
G Drd3 dopamine receptor D3 IDA RGD PMID:11675403 RGD:1580882 NCBI chr11:61,819,102...61,883,223
Ensembl chr11:61,822,077...61,874,327 		JBrowse link
G Drd5 dopamine receptor D5 ISO RGD PMID:12486173 RGD:1580887 NCBI chr14:77,220,579...77,222,006
Ensembl chr14:77,220,579...77,222,006 		JBrowse link
G Dusp1 dual specificity phosphatase 1 IEP mRNA, protein:increased expression:aorta RGD PMID:9231829 RGD:2298678 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418 		JBrowse link
G Dusp5 dual specificity phosphatase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25397684 NCBI chr 1:274,245,184...274,258,595
Ensembl chr 1:274,245,184...274,258,595 		JBrowse link
G Dynll1 dynein light chain LC8-type 1 treatment IMP RGD PMID:24035314 RGD:13207430 NCBI chr12:47,074,200...47,076,573
Ensembl chr12:47,074,200...47,076,572 		JBrowse link
G Ece1 endothelin converting enzyme 1 IDA
ISO
IEP		 CTD Direct Evidence: marker/mechanism
mRNA,protein:increased expression,increased activity:kidney medulla		 CTD PMID:12566389, PMID:12193123, PMID:10894793 RGD:1580907, RGD:7244182 NCBI chr 5:156,215,469...156,318,652
Ensembl chr 5:156,215,417...156,318,671 		JBrowse link
G Edn1 endothelin 1 IEP
ISO		 protein:increased secretion:plasma (rat)
CTD Direct Evidence: marker/mechanism
human gene in a rat model
associated with Diabetic Nephropathies;protein:increased secretion:plasma
DNA:polymorphism:exon:p.K198N (human)		 CTD PMID:7721406 PMID:8152482 PMID:8440307 PMID:10474778 PMID:10669576 PMID:11847185 PMID:12149661 PMID:12425201 PMID:12600921 PMID:15188945 PMID:15302986 PMID:15314687 PMID:15834289 PMID:17130675, PMID:20733093, PMID:11078355, PMID:18496905, PMID:17444275 RGD:4144829, RGD:8661804, RGD:2313283, RGD:1625065 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324 		JBrowse link
G Edn2 endothelin 2 ISO mRNA:increased expression:leukocyte RGD PMID:10976780, PMID:10489105, PMID:15007037 RGD:1580916, RGD:1580917, RGD:1625402 NCBI chr 5:139,098,472...139,106,396
Ensembl chr 5:139,100,898...139,105,792 		JBrowse link
G Edn3 endothelin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:2059916 NCBI chr 3:172,856,730...172,879,276
Ensembl chr 3:172,856,733...172,880,450 		JBrowse link
G Ednra endothelin receptor type A IEP
ISO
IDA		 associated with Uremia
CTD Direct Evidence: marker/mechanism		 CTD PMID:12600921, PMID:20144075, PMID:14616768, PMID:16157796 RGD:4892284, RGD:1580950, RGD:1581830 NCBI chr19:33,928,356...33,991,703
Ensembl chr19:33,928,356...33,991,703 		JBrowse link
G Ednrb endothelin receptor type B IEP
IMP		 associated with Uremia RGD PMID:20144075, PMID:10749572 RGD:4892284, RGD:628518 NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354 		JBrowse link
G Egfr epidermal growth factor receptor IEP mRNA, protein:increased expression:renal cortex RGD PMID:15827348 RGD:1580953 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796 		JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 IMP RGD PMID:22686466 RGD:11252087 NCBI chr19:57,660,194...57,701,158
Ensembl chr19:57,662,278...57,699,113 		JBrowse link
G Eif4g2 eukaryotic translation initiation factor 4, gamma 2 IEP mRNA:increased expression:heart left ventricle RGD PMID:12708758 RGD:10755511 NCBI chr 1:175,883,362...175,895,510
Ensembl chr 1:175,883,363...175,895,510 		JBrowse link
G Eln elastin ISO CTD Direct Evidence: marker/mechanism CTD PMID:17039479 NCBI chr12:24,978,478...25,021,864
Ensembl chr12:24,978,483...25,021,863 		JBrowse link
G Emilin1 elastin microfibril interfacer 1 ISO RGD PMID:16530041 RGD:1580958 NCBI chr 6:26,821,249...26,829,013
Ensembl chr 6:26,821,255...26,828,972 		JBrowse link
G Eng endoglin IEP mRNA:decreased expression:kidney (rat) RGD PMID:19829664 RGD:4892132 NCBI chr 3:11,679,530...11,717,486
Ensembl chr 3:11,679,530...11,717,485 		JBrowse link
G Eno1 enolase 1 IEP RGD PMID:16485256 RGD:1598909 NCBI chr 5:167,288,223...167,299,610
Ensembl chr 5:167,288,223...167,299,609 		JBrowse link
G Eno2 enolase 2 severity ISO protein:increased expression:serum RGD PMID:21130083 RGD:5508770 NCBI chr 4:157,285,192...157,294,090
Ensembl chr 4:157,285,179...157,294,047 		JBrowse link
G Entpd2 ectonucleoside triphosphate diphosphohydrolase 2 IEP RGD PMID:20655932 RGD:9685529 NCBI chr 3:2,617,795...2,623,818
Ensembl chr 3:2,617,805...2,623,445 		JBrowse link
G Ep300 E1A binding protein p300 IEP protein:increased expression:left ventricle (rat) RGD PMID:18292809 RGD:2312265 NCBI chr 7:122,818,194...122,889,055
Ensembl chr 7:122,818,975...122,861,296 		JBrowse link
G Ephx2 epoxide hydrolase 2 susceptibility IDA
IMP
ISO		 DNA:missense mutation:cds:p.K55R (human) RGD PMID:16157792, PMID:21720266, PMID:19553349, PMID:20065888 RGD:1580985, RGD:5688733, RGD:5688730, RGD:5688727 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279 		JBrowse link
G Epo erythropoietin ISO CTD Direct Evidence: marker/mechanism CTD PMID:1516988 PMID:10694834 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266 		JBrowse link
G Epor erythropoietin receptor susceptibility ISO induced by erythropoietin; RGD PMID:19458615 RGD:11041646 NCBI chr 8:22,969,737...22,974,468
Ensembl chr 8:22,969,745...22,974,321 		JBrowse link
G Erap1 endoplasmic reticulum aminopeptidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:13678427 NCBI chr 2:1,410,877...1,449,734
Ensembl chr 2:1,410,934...1,449,733 		JBrowse link
G Esr2 estrogen receptor 2 ISO
IMP		 RGD PMID:11799247, PMID:23608653, PMID:11185739, PMID:15167447 RGD:734949, RGD:7364951, RGD:1581015, RGD:1581017 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251 		JBrowse link
G F11 coagulation factor XI ISO CTD Direct Evidence: marker/mechanism CTD PMID:6383834 NCBI chr16:50,179,458...50,201,644
Ensembl chr16:50,179,458...50,201,698 		JBrowse link
G F11r F11 receptor susceptibility ISO
IEP		 DNA:SNPs: :rs790056, rs2774276 (human) RGD PMID:18067551, PMID:17420334 RGD:7488938, RGD:7488939 NCBI chr13:89,826,272...89,850,151
Ensembl chr13:89,826,254...89,850,612 		JBrowse link
G F12 coagulation factor XII ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: High blood pressure		 CTD
ClinVar		 PMID:6383834 PMID:16638441 PMID:25741868 NCBI chr17:9,736,577...9,744,420
Ensembl chr17:9,736,577...9,744,420 		JBrowse link
G F2r coagulation factor II (thrombin) receptor IDA RGD PMID:9168786 RGD:1581034 NCBI chr 2:26,118,760...26,135,340
Ensembl chr 2:26,118,760...26,135,340 		JBrowse link
G F3 coagulation factor III, tissue factor treatment IEP RGD PMID:21423288 RGD:11341709 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272 		JBrowse link
G F7 coagulation factor VII ISO
IEP		 protein:increased activity:plasma (human)
protein:increased activity:plasma (rat)		 RGD PMID:10450539, PMID:8123879, PMID:812575 RGD:2312402, RGD:2312412, RGD:2312323 NCBI chr16:81,824,610...81,834,923
Ensembl chr16:81,824,111...81,834,945 		JBrowse link
G Fabp1 fatty acid binding protein 1 ISO possibly associated with arteriosclerosis (MeSH:D001161) RGD PMID:15830271 RGD:1626441 NCBI chr 4:99,063,181...99,066,957
Ensembl chr 4:99,063,181...99,066,954 		JBrowse link
G Fabp3 fatty acid binding protein 3 susceptibility ISO DNA:SNPs RGD PMID:18437121 RGD:2307331 NCBI chr 5:148,528,854...148,535,597
Ensembl chr 5:148,528,725...148,535,565 		JBrowse link
G Fadd Fas associated via death domain treatment IEP RGD PMID:24355328 RGD:11344883 NCBI chr 1:217,746,176...217,748,581
Ensembl chr 1:217,742,929...217,748,628 		JBrowse link
G Fads1 fatty acid desaturase 1 IEP RGD PMID:12144877 RGD:1625415 NCBI chr 1:226,234,034...226,249,118
Ensembl chr 1:226,234,074...226,249,138 		JBrowse link
G Fah fumarylacetoacetate hydrolase IEP mRNA:decreased expression:kidney RGD PMID:15731461 RGD:1559295 NCBI chr 1:146,713,663...146,736,339
Ensembl chr 1:146,713,676...146,736,261 		JBrowse link
G Fbn1 fibrillin 1 IEP protein:increased expression:renal glomerulus (rat) RGD PMID:16380460 RGD:7365080 NCBI chr 3:117,569,708...117,766,160
Ensembl chr 3:117,569,697...117,766,120 		JBrowse link
G Fgf2 fibroblast growth factor 2 IEP associated with Aortic Coarctation RGD PMID:17562191 RGD:8655614 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681 		JBrowse link
G Fgf21 fibroblast growth factor 21 ISO CTD Direct Evidence: therapeutic CTD PMID:29706566 NCBI chr 1:101,595,579...101,596,822
Ensembl chr 1:101,595,579...101,596,822 		JBrowse link
G Fmo3 flavin containing dimethylaniline monoxygenase 3 no_association ISO associated with trimethylaminuria, OMIM:602079 RGD PMID:9536088, PMID:16324215 RGD:1626461, RGD:1626466 NCBI chr13:80,837,418...80,856,214
Ensembl chr13:80,837,420...80,862,963 		JBrowse link
G Fn1 fibronectin 1 ISO
IEP
IAGP		 CTD Direct Evidence: marker/mechanism
mRNA:increased expression:kidney (SHRSP/A3N rat)		 CTD PMID:11682445 PMID:17324946, PMID:11907153, PMID:11682445 RGD:28912746, RGD:30296650 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078 		JBrowse link
G Fndc5 fibronectin type III domain containing 5 ISO CTD Direct Evidence: therapeutic CTD PMID:32165127 NCBI chr 5:147,323,240...147,330,266
Ensembl chr 5:147,323,240...147,330,266 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit IEP
ISO		 CTD Direct Evidence: marker/mechanism CTD PMID:12044476 PMID:24039778, PMID:16696897 RGD:7242185 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299 		JBrowse link
G Foxp3 forkhead box P3 treatment IEP RGD PMID:24420551 RGD:38549366 NCBI chr  X:15,753,175...15,768,648
Ensembl chr  X:15,753,175...15,768,522 		JBrowse link
G Fxyd2 FXYD domain-containing ion transport regulator 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22228705 NCBI chr 8:49,710,334...49,717,492
Ensembl chr 8:49,710,477...49,716,955 		JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 IEP mRNA:increased expression:brain RGD PMID:18338268 RGD:2315462 NCBI chr20:1,955,344...1,984,907
Ensembl chr20:1,955,359...1,984,863 		JBrowse link
G Gad1 glutamate decarboxylase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:32165127 NCBI chr 3:56,861,440...56,902,139
Ensembl chr 3:56,861,396...56,902,157 		JBrowse link
G Gal galanin and GMAP prepropeptide IEP
ISO		 mRNA:decreased expression:paraventricular hypothalamic nucleus, solitary tract nucleus
CTD Direct Evidence: marker/mechanism		 CTD PMID:10818254, PMID:15275958 RGD:1624333 NCBI chr 1:218,653,059...218,657,922
Ensembl chr 1:218,652,917...218,657,925 		JBrowse link
G Gcg glucagon ISO CTD Direct Evidence: marker/mechanism CTD PMID:22228705 NCBI chr 3:48,442,635...48,451,650
Ensembl chr 3:48,442,635...48,451,650 		JBrowse link
G Gch1 GTP cyclohydrolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12855421 NCBI chr15:23,935,011...23,968,971
Ensembl chr15:23,934,585...23,969,011 		JBrowse link
G Gck glucokinase susceptibility ISO RGD PMID:9324112 RGD:1581877 NCBI chr14:86,149,146...86,191,589
Ensembl chr14:86,148,928...86,190,659 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:22228705 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468 		JBrowse link
G Ghsr growth hormone secretagogue receptor ISO associated with Obesity RGD PMID:24760503 RGD:12910115 NCBI chr 2:113,065,953...113,071,265
Ensembl chr 2:113,066,885...113,070,261 		JBrowse link
G Gja1 gap junction protein, alpha 1 treatment IEP
ISO		 CTD Direct Evidence: marker/mechanism CTD PMID:16448880, PMID:16448880, PMID:23719203 RGD:7207810, RGD:8662439 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089 		JBrowse link
G Gja4 gap junction protein, alpha 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16448880 NCBI chr 5:145,374,688...145,377,221
Ensembl chr 5:145,374,690...145,377,221 		JBrowse link
G Gja5 gap junction protein, alpha 5 treatment IDA
ISO
IEP		 CTD Direct Evidence: marker/mechanism
protein:decreased expression:artery endothelium 		CTD PMID:19109587, PMID:19686729, PMID:11821709 RGD:7207417, RGD:7207848 NCBI chr 2:199,162,745...199,184,942
Ensembl chr 2:199,162,745...199,184,939 		JBrowse link
G Gjc1 gap junction protein, gamma 1 ISO CTD Direct Evidence: therapeutic CTD PMID:19109587 NCBI chr10:90,781,408...90,912,440
Ensembl chr10:90,781,402...90,912,287 		JBrowse link
G Glp1r glucagon-like peptide 1 receptor IDA
ISO		 CTD Direct Evidence: marker/mechanism CTD PMID:22228705, PMID:12093887 RGD:625448 NCBI chr20:9,586,075...9,626,228
Ensembl chr20:9,586,075...9,626,228 		JBrowse link
G Gnai2 G protein subunit alpha i2 treatment IMP
IEP		 RGD PMID:27912212, PMID:15106810 RGD:13507308, RGD:13508592 NCBI chr 8:116,370,730...116,391,337
Ensembl chr 8:116,370,744...116,391,307 		JBrowse link
G Gnai3 G protein subunit alpha i3 treatment IEP RGD PMID:15106810 RGD:13508592 NCBI chr 2:210,896,779...210,934,733
Ensembl chr 2:210,896,656...210,934,749 		JBrowse link
G Gnas GNAS complex locus ISO CTD Direct Evidence: marker/mechanism CTD PMID:9506701, PMID:12215464, PMID:15118671 RGD:1580404, RGD:1331525 NCBI chr 3:172,374,957...172,434,988
Ensembl chr 3:172,374,957...172,428,483
Ensembl chr 3:172,374,957...172,428,483 		JBrowse link
G Gnb3 G protein subunit beta 3 susceptibility
no_association		 ISO DNA:SNP:cds:825C>T (human)
CTD Direct Evidence: marker/mechanism
DNA:SNP:cds: 825C>T (human)
DNA:polymorphism: :multiple (human)		 CTD PMID:15961981 PMID:16141801, PMID:10526907, PMID:11230982, PMID:16908025 RGD:1580410, RGD:1580408, RGD:2313206 NCBI chr 4:157,352,558...157,359,237
Ensembl chr 4:157,352,372...157,358,262 		JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:6350720 NCBI chr15:44,441,856...44,446,064
Ensembl chr15:44,442,555...44,442,875
Ensembl chr15:44,442,555...44,442,875 		JBrowse link
G Gp1ba glycoprotein Ib platelet subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:22352330 NCBI chr10:57,260,680...57,263,546
Ensembl chr10:57,260,680...57,263,546 		JBrowse link
G Gpx1 glutathione peroxidase 1 treatment ISO
IDA
IEP		 CTD Direct Evidence: marker/mechanism CTD PMID:21593737, PMID:17198913, PMID:21210316, PMID:23752977 RGD:1600704, RGD:11353777, RGD:11352825 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 treatment IEP
ISO		 protein:increased expression:lymphocyte, vascular associated smooth muscle cell
CTD Direct Evidence: marker/mechanism		 CTD PMID:11901213, PMID:10642272, PMID:23913704 RGD:1625788, RGD:13792716 NCBI chr 1:219,536,220...219,544,329
Ensembl chr 1:219,536,220...219,544,328 		JBrowse link
G Grk3 G protein-coupled receptor kinase 3 IEP mRNA:increased expression:heart left ventricle, kidney (rat) RGD PMID:26248277 RGD:11535540 NCBI chr12:49,626,871...49,750,389
Ensembl chr12:49,626,871...49,746,272 		JBrowse link
G Grk5 G protein-coupled receptor kinase 5 IEP mRNA:increased expression:heart left ventricle, kidney (rat) RGD PMID:26248277 RGD:11535540 NCBI chr 1:282,265,371...282,467,842
Ensembl chr 1:282,265,370...282,462,605 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta treatment IEP
ISO		 CTD Direct Evidence: marker/mechanism CTD PMID:22982863, PMID:22982863 RGD:10045670 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268 		JBrowse link
G Gsr glutathione-disulfide reductase ISO RGD PMID:17198913 RGD:1600704 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361 		JBrowse link
G Gsta5 glutathione S-transferase alpha 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22228705 NCBI chr 8:85,553,659...85,564,914
Ensembl chr 8:85,553,734...85,565,179 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 IEP mRNA:decreased expression:kidney (rat) RGD PMID:15699453 RGD:7495838 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306 		JBrowse link
G Gstm2 glutathione S-transferase mu 2 IEP mRNA:decreased expression:kidney (rat) RGD PMID:18008142, PMID:12624007 RGD:2302178, RGD:631154 NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24915237 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 ISO associated with scleroderma, systemic;DNA:deletion: :
CTD Direct Evidence: marker/mechanism		 CTD PMID:22228705, PMID:11477481 RGD:5490587 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526 		JBrowse link
G Gstt2 glutathione S-transferase, theta 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22228705 NCBI chr20:13,760,810...13,764,481
Ensembl chr20:13,760,810...13,764,475 		JBrowse link
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18339647 NCBI chr 2:181,045,694...181,103,321
Ensembl chr 2:181,045,703...181,102,918 		JBrowse link
G H2ax H2A.X variant histone treatment IDA RGD PMID:24239235 RGD:8693672 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 IEP protein:increased expression:urine RGD PMID:23085980 RGD:7245484 NCBI chr10:31,813,819...31,860,934
Ensembl chr10:31,813,814...31,848,379 		JBrowse link
G Hdac6 histone deacetylase 6 IEP protein:increased expression, activity:heart: RGD PMID:23868068 RGD:9681716 NCBI chr  X:15,295,372...15,316,673
Ensembl chr  X:15,295,473...15,316,671 		JBrowse link
G Hdac8 histone deacetylase 8 IEP protein:decreased expression:heart (mouse, rat) RGD PMID:28567090 RGD:13208602 NCBI chr  X:72,163,777...72,370,058
Ensembl chr  X:72,163,777...72,370,044 		JBrowse link
G Hgf hepatocyte growth factor susceptibility ISO DNA:polymorphism:intron13:C/A RGD PMID:15127882, PMID:15127882 RGD:1642064, RGD:1642064 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha ISO
IEP		 Hypertension, Pregnancy-Induced;mRNA, protein:increased expression:placenta
CTD Direct Evidence: therapeutic
associated with Hypercholesterolemia;protein:increased expression:aorta
protein:increased expression:brain		 CTD PMID:22349312, PMID:15862159, PMID:11882589, PMID:16955051 RGD:1626322, RGD:1626330, RGD:1626317 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052 		JBrowse link
G Hmgb1 high mobility group box 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:32147540 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237 		JBrowse link
G Hmox1 heme oxygenase 1 susceptibility
treatment		 ISO
IDA		 CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:16959961 PMID:22349312 PMID:22352330, PMID:12872043, PMID:20836698, PMID:12215473 RGD:1598400, RGD:10755717, RGD:1580453 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456 		JBrowse link
G Hp haptoglobin susceptibility
onset		 ISO
IEP		 DNA:polymorphism
CTD Direct Evidence: marker/mechanism		 CTD PMID:16597321, PMID:7606649, PMID:23401751, PMID:8228210 RGD:1626351, RGD:7241867, RGD:1626352 NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804 		JBrowse link
G Hrh2 histamine receptor H 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30310171 NCBI chr17:10,912,959...10,931,389
Ensembl chr17:10,921,507...10,952,441 		JBrowse link
G Hrh3 histamine receptor H3 IDA
ISO		 CTD Direct Evidence: marker/mechanism CTD PMID:9050021, PMID:9050021 RGD:1626409 NCBI chr 3:175,474,310...175,479,395
Ensembl chr 3:175,473,078...175,479,395 		JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9683905 PMID:15199296 PMID:21786805 NCBI chr13:111,946,626...111,996,536
Ensembl chr13:111,926,442...111,972,603 		JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 IEP
ISO		 associated with Diabetes Mellitus, Experimental;mRNA:decreased expression:kidney
CTD Direct Evidence: marker/mechanism
apparent mineralocorticoid excess syndrome, OMIM:218030		 CTD PMID:7670488 PMID:9683905 PMID:9707624 PMID:11082157, PMID:10792625, PMID:9683587 RGD:2308925, RGD:1625078 NCBI chr19:37,476,083...37,481,326
Ensembl chr19:37,476,095...37,481,307 		JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 IEP mRNA:decreased expression:renal cortex (rat) RGD PMID:18430809 RGD:2292646 NCBI chr18:44,810,462...44,897,677
Ensembl chr18:44,810,388...44,897,640 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 susceptibility IEP
ISO		 mRNA:decreased expression:ovary (rat)
DNA:polymorphism:exon		 RGD PMID:19228890, PMID:12054649 RGD:4761326, RGD:1626438
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 IEP mRNA:increased expression:hypothalamus (rat) RGD PMID:16116051 RGD:1599701 NCBI chr 2:200,712,895...200,722,429
Ensembl chr 2:202,341,422...202,350,929 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 ISO mRNA: increased expression: leukocyte RGD PMID:17341625 RGD:6480224 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 IEP mRNA:increased expression:brain, blood vessel RGD PMID:15729290, PMID:18948349 RGD:1624213, RGD:10402862 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956 		JBrowse link
G Hspg2 heparan sulfate proteoglycan 2 IEP mRNA:increased expression:aorta RGD PMID:8225534 RGD:1624258 NCBI chr 5:155,812,096...155,913,751 JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B IEP protein:increased expression:aorta RGD PMID:11882579 RGD:1626447 NCBI chr 8:89,113,984...89,130,830
Ensembl chr 8:89,129,453...89,130,991 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A susceptibility
no_association		 ISO DNA:polymorphism: :102T>C
DNA:polymorphism: :g.102T>C		 RGD
GAD		 PMID:11378836, PMID:15118671, PMID:15659047 RGD:1624375, RGD:1331525, RGD:1624371 NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382 		JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B ISO CTD Direct Evidence: marker/mechanism CTD PMID:8627522 NCBI chr 9:93,112,781...93,130,135
Ensembl chr 9:93,112,805...93,125,014 		JBrowse link
G Htra1 HtrA serine peptidase 1 ISO associated with Macular Degeneration; DNA:snp:cds:g.102C>T (rs1049331) (human) RGD PMID:21682878 RGD:7394697 NCBI chr 1:201,499,067...201,548,508
Ensembl chr 1:201,499,028...201,548,513 		JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:serum
CTD Direct Evidence: marker/mechanism		 CTD PMID:12149661 PMID:12425201, PMID:18619052 RGD:2312765 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059 		JBrowse link
G Ier3 immediate early response 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20713914 NCBI chr20:3,438,798...3,440,002
Ensembl chr20:3,438,798...3,440,769 		JBrowse link
G Igf1 insulin-like growth factor 1 severity ISO
IEP
IAGP		 mRNA:increased expression:aorta (rat)
CTD Direct Evidence: marker/mechanism|therapeutic		 CTD PMID:19502719 PMID:22228705, PMID:16431135, PMID:8418983, PMID:15996002 RGD:1598427, RGD:12904968, RGD:1580474 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor IEP protein:increased expression:aorta: RGD PMID:21854769 RGD:10046007 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516 		JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 IEP mRNA, protein:decreased expression:liver, plasma RGD PMID:9396554 RGD:1626482 NCBI chr 9:80,118,029...80,144,804
Ensembl chr 9:80,118,029...80,144,789 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta treatment IEP
ISO		 CTD Direct Evidence: marker/mechanism CTD PMID:27659729 PMID:32147540, PMID:19246475 RGD:7495780 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815 		JBrowse link
G Il10 interleukin 10 IEP RGD PMID:19398662 RGD:2311047 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392 		JBrowse link
G Il1b interleukin 1 beta IEP
ISO
IDA		 mRNA, protein:increased expression:aorta, plasma
CTD Direct Evidence: marker/mechanism
associated with Obesity;protein:increased expression:plasma		 CTD PMID:27292124 PMID:27659729 PMID:27847271 PMID:32147540 PMID:32165127, PMID:15894892, PMID:21173343, PMID:15990729 RGD:1626635, RGD:7175338, RGD:1626638 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726 		JBrowse link
G Il1rn interleukin 1 receptor antagonist susceptibility IDA
ISO		 DNA:polymorphisms RGD PMID:11585563, PMID:11840488 RGD:1626668, RGD:1626667 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614 		JBrowse link
G Il6 interleukin 6 susceptibility ISO associated with end stage renal disease; DNA:polymorphisms:promoter: -174G>C (human)
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:increased expression:extracellular space (human)		 CTD PMID:27292124 PMID:27659729 PMID:27847271 PMID:32147540 PMID:32165127, PMID:12846758, PMID:19043252 RGD:1580485, RGD:2307283 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807 		JBrowse link
G Il6r interleukin 6 receptor severity ISO Hypertension, Pregnancy-Induced;protein:increased expression:serum RGD PMID:11778537 RGD:1625432 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628 		JBrowse link
G Il6st interleukin 6 cytokine family signal transducer severity ISO Hypertension, Pregnancy-Induced;protein:increased expression:serum RGD PMID:11778537 RGD:1625432 NCBI chr 2:44,279,199...44,319,427
Ensembl chr 2:44,289,393...44,314,944 		JBrowse link
G Inppl1 inositol polyphosphate phosphatase-like 1 ISO DNA:SNPs: :rs2276047,snp8,rs9886(human)
CTD Direct Evidence: marker/mechanism		 CTD PMID:15220217, PMID:15220217 RGD:1626127 NCBI chr 1:166,898,177...166,912,524
Ensembl chr 1:166,899,894...166,912,524 		JBrowse link
G Ins2 insulin 2 IDA
ISO		 CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:9719048 PMID:18360027, PMID:9095092 RGD:6902896 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034 		JBrowse link
G Itga9 integrin subunit alpha 9 susceptibility ISO DNA:SNP: :rs155524(human) RGD PMID:20479155 RGD:13602005 NCBI chr 8:127,271,029...127,576,709
Ensembl chr 8:127,271,289...127,572,988 		JBrowse link
G Itgav integrin subunit alpha V IEP protein:increased expression:artery RGD PMID:16380536 RGD:1627642 NCBI chr 3:71,113,269...71,205,958
Ensembl chr 3:71,114,100...71,202,411 		JBrowse link
G Itm2b integral membrane protein 2B ISO CTD Direct Evidence: marker/mechanism CTD PMID:22228705 NCBI chr15:55,254,703...55,277,713
Ensembl chr15:55,254,706...55,277,713 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit IDA
ISO		 CTD Direct Evidence: marker/mechanism CTD PMID:24039778, PMID:11358932 RGD:10047414 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277 		JBrowse link
G Kcna5 potassium voltage-gated channel subfamily A member 5 IEP mRNA:increased expression:heart RGD PMID:11358947 RGD:1627659 NCBI chr 4:159,077,195...159,079,003
Ensembl chr 4:159,077,195...159,079,003 		JBrowse link
G Kcnab1 potassium voltage-gated channel subfamily A member regulatory beta subunit 1 IEP mRNA:increased expression:aorta, arteries (rat) RGD PMID:11358947 RGD:1627659 NCBI chr 2:155,555,798...156,011,438
Ensembl chr 2:155,718,359...156,009,526 		JBrowse link
G Kcnj1 potassium inwardly-rectifying channel, subfamily J, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22228705 NCBI chr 8:33,490,280...33,519,127
Ensembl chr 8:33,514,042...33,518,165 		JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 IEP RGD PMID:15964031 RGD:1598644 NCBI chr 1:102,103,093...102,107,134
Ensembl chr 1:102,103,094...102,106,127 		JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 IDA RGD PMID:16051697 RGD:1581698 NCBI chr 4:176,783,287...176,789,143
Ensembl chr 4:176,782,498...176,789,304 		JBrowse link
G Kcnmb1 potassium calcium-activated channel subfamily M regulatory beta subunit 1 IDA
ISO
IEP		 CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:aorta, mesenteric artery		 CTD PMID:17700361, PMID:14551242, PMID:16814121, PMID:16293791 RGD:1298970, RGD:10412046, RGD:1581718 NCBI chr10:18,910,586...18,922,856
Ensembl chr10:18,906,010...18,919,639 		JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 IAGP DNA:deletion:exon (rat) RGD PMID:16368876 RGD:1581602 NCBI chr 1:216,293,087...216,630,339
Ensembl chr 1:216,293,087...216,630,339 		JBrowse link
G Kcnq1dfk potassium voltage-gated channel subfamily Q member 1;deafness Kyoto IAGP RGD PMID:16368876 RGD:1581602
G Kdr kinase insert domain receptor treatment IEP
ISO		 DNA:polymorphism:cds:p.H472Q(human) RGD PMID:15838270, PMID:20630084 RGD:5684418, RGD:8552374 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183 		JBrowse link
G Kl Klotho treatment IDA
IEP
ISO		 mRNA,protein:decreased expression:kidney: RGD PMID:10892340, PMID:21051829, PMID:23225045 RGD:1581732, RGD:10403063, RGD:10403062 NCBI chr12:942,974...987,206
Ensembl chr12:943,006...987,551 		JBrowse link
G Klk1 kallikrein 1 no_association
susceptibility		 ISO
IEP		 DNA:polymorphisms
CTD Direct Evidence: therapeutic
mRNA:decreased expression:kidney		 RGD
CTD		 PMID:14568997 PMID:15905889, PMID:15167446, PMID:15809361 RGD:1641795, RGD:1581751, RGD:1358144 NCBI chr 1:100,131,562...100,135,556
Ensembl chr 1:100,059,967...100,203,329
Ensembl chr 1:100,059,967...100,203,329
Ensembl chr 1:100,059,967...100,203,329 		JBrowse link
G Klk1b3 kallikrein 1-related peptidase B3 IAGP RGD PMID:15809361 RGD:1358144 NCBI chr 1:100,199,057...100,203,260
Ensembl chr 1:100,059,967...100,203,329 		JBrowse link
G Klk1c12 kallikrein 1-related peptidase C12 ISO DNA:polymorphisms RGD PMID:15905889, PMID:17272402 RGD:1641795, RGD:1641794 NCBI chr 1:99,298,965...99,303,048
Ensembl chr 1:99,299,011...99,303,048 		JBrowse link
G Klkb1 kallikrein B1 ISO associated with Diabetes Mellitus, Type 1; protein:increased expression:plasma: RGD PMID:12716755 RGD:7327151 NCBI chr16:50,151,127...50,175,407
Ensembl chr16:50,152,008...50,175,458 		JBrowse link
G Kng2 kininogen 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:7027322 NCBI chr11:81,509,185...81,516,759 JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO RGD PMID:15864294 RGD:1581757 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558 		JBrowse link
G Kynu kynureninase IAGP RGD PMID:11924719 RGD:631322 NCBI chr 3:28,416,926...28,566,939
Ensembl chr 3:28,416,954...28,566,928 		JBrowse link
G Lep leptin ISO
IDA		 DNA:SNPs: :
CTD Direct Evidence: marker/mechanism		 CTD PMID:12050272 PMID:16827954 PMID:25205467 PMID:27226618, PMID:19204185, PMID:20059648 RGD:5128788, RGD:5128597 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818 		JBrowse link
G Lepr leptin receptor disease_progression ISO
IMP		 DNA:polymorphisms:exons
CTD Direct Evidence: marker/mechanism		 CTD PMID:22949526, PMID:10999797, PMID:27465994 RGD:5129161, RGD:12911217 NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221 		JBrowse link
G Leprem2Mcwi leptin receptor; zinc finger nuclease induced mutant 2, Medical College of Wisconsin disease_progression IMP RGD PMID:27465994 RGD:12911217
G Lgals3 galectin 3 treatment IEP RGD PMID:23117656 RGD:9685203 NCBI chr15:24,153,602...24,165,537
Ensembl chr15:24,141,651...24,165,537 		JBrowse link
G Lhb luteinizing hormone subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:6350720 NCBI chr 1:101,409,992...101,413,725
Ensembl chr 1:101,410,019...101,413,724 		JBrowse link
G Lipe lipase E, hormone sensitive type ISO gestational hypertension;DNA:polymorphism:promoter:-60C>G RGD PMID:17318300 RGD:1625026 NCBI chr 1:82,248,031...82,266,727
Ensembl chr 1:82,248,046...82,266,727 		JBrowse link
G Lipg lipase G, endothelial type IDA RGD PMID:15914124 RGD:1581875 NCBI chr18:70,903,528...70,924,434
Ensembl chr18:70,901,710...70,924,708 		JBrowse link
G Lox lysyl oxidase ISO
IDA		 RGD PMID:8562290, PMID:24127 RGD:1581896, RGD:1581899 NCBI chr18:47,500,320...47,577,819
Ensembl chr18:47,500,330...47,577,819 		JBrowse link
G Lpl lipoprotein lipase ISO CTD Direct Evidence: marker/mechanism CTD PMID:22228705, PMID:16132104 RGD:1580535 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496 		JBrowse link
G Lrp2 LDL receptor related protein 2 IDA protein:altered localization:apical plasma membrane RGD PMID:10919857 RGD:1641827 NCBI chr 3:55,665,153...55,822,484
Ensembl chr 3:55,665,145...55,822,551 		JBrowse link
G Lta lymphotoxin alpha no_association ISO RGD PMID:15533732 RGD:1580415 NCBI chr20:4,851,889...4,854,677
Ensembl chr20:4,852,496...4,854,677 		JBrowse link
G Ltf lactotransferrin ISO CTD Direct Evidence: therapeutic CTD PMID:24587916 NCBI chr 8:119,290,416...119,313,261
Ensembl chr 8:119,290,416...119,313,261 		JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha IEP RGD PMID:23499735 RGD:11561939 NCBI chr 3:150,801,289...150,802,935
Ensembl chr 3:150,801,289...150,802,935 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 IDA RGD PMID:15302844 RGD:1582315 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347 		JBrowse link
G Mas1 MAS1 proto-oncogene, G protein-coupled receptor IMP associated with Sleep Apnea Syndromes RGD PMID:21040717 RGD:5129169 NCBI chr 1:48,076,761...48,108,218
Ensembl chr 1:48,077,033...48,108,216 		JBrowse link
G Mc2r melanocortin 2 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:11082157 NCBI chr18:64,166,959...64,178,729
Ensembl chr18:64,167,191...64,177,729 		JBrowse link
G Mdh1 malate dehydrogenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22228705 NCBI chr14:106,378,349...106,393,642
Ensembl chr14:106,378,942...106,393,670 		JBrowse link
G Mfn2 mitofusin 2 treatment IEP protein:decreased expression:aorta (rat) RGD PMID:27847271, PMID:25464244 RGD:12910764, RGD:13204764 NCBI chr 5:164,684,244...164,715,414
Ensembl chr 5:164,684,509...164,714,145 		JBrowse link
G Mif macrophage migration inhibitory factor IDA RGD PMID:19799867 RGD:4890974 NCBI chr20:13,715,219...13,732,980
Ensembl chr20:13,732,198...13,732,859 		JBrowse link
G Mir214 microRNA 214 treatment IMP RGD PMID:30049682 RGD:38500245 NCBI chr13:80,130,905...80,131,014 JBrowse link
G Mme membrane metallo-endopeptidase treatment IMP RGD PMID:12011651 RGD:13801039 NCBI chr 2:153,799,203...153,880,910
Ensembl chr 2:153,803,349...153,880,738 		JBrowse link
G Mmp1 matrix metallopeptidase 1 ISO protein:decreased expression:renal glomerulus (human) RGD PMID:15363819, PMID:19506087 RGD:1582532, RGD:2312464 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591 		JBrowse link
G Mmp2 matrix metallopeptidase 2 IEP
ISO		 mRNA, protein:increased expression:kidney
CTD Direct Evidence: marker/mechanism		 CTD PMID:18836702, PMID:17977875, PMID:16840178 RGD:2290351, RGD:1582612 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611 		JBrowse link
G Mmp7 matrix metallopeptidase 7 treatment IMP
IEP		 RGD PMID:19398663, PMID:19398663 RGD:9685347, RGD:9685347 NCBI chr 8:5,893,253...5,900,965
Ensembl chr 8:5,893,249...5,901,049 		JBrowse link
G Mmp9 matrix metallopeptidase 9 susceptibility ISO
IEP		 protein:decreased expression:internal mammary artery
CTD Direct Evidence: marker/mechanism
associated with Aneurysm, Dissecting;DNA:polymorphism:promoter:-1562C>T		 CTD PMID:21051829, PMID:15363819, PMID:16780738, PMID:16840178, PMID:17977875 RGD:1582532, RGD:1642029, RGD:1582612, RGD:2290351 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520 		JBrowse link
G Mov10 Mov10 RISC complex RNA helicase susceptibility ISO DNA:SNP: :rs2932538(human) RGD PMID:24338417 RGD:13513987 NCBI chr 2:207,277,088...207,301,245
Ensembl chr 2:207,278,161...207,300,854 		JBrowse link
G Moxd2 monooxygenase, DBH-like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:3814904 NCBI chr 4:69,117,477...69,125,972
Ensembl chr 4:69,117,477...69,125,972 		JBrowse link
G Msx2 msh homeobox 2 IEP RGD PMID:18270471 RGD:5132616 NCBI chr17:11,683,862...11,689,527
Ensembl chr17:11,683,862...11,689,527 		JBrowse link
G Mtor mechanistic target of rapamycin kinase IDA
ISO		 protein:increased serine phosphorylation:kidney
CTD Direct Evidence: marker/mechanism		 CTD PMID:19289642, PMID:23323219 RGD:10041025 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967 		JBrowse link
G Mtpn myotrophin IEP
IDA		 RGD PMID:12419325, PMID:12031792 RGD:632799, RGD:1581046 NCBI chr 4:63,012,009...63,039,422
Ensembl chr 4:63,012,011...63,039,422 		JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase ISO RGD PMID:15148588 RGD:1581050 NCBI chr17:66,210,444...66,295,014
Ensembl chr17:66,210,461...66,295,014 		JBrowse link
G Mttp microsomal triglyceride transfer protein onset ISO DNA:polymorphism:promoter:-493G>T RGD PMID:16328015 RGD:1625485 NCBI chr 2:243,366,181...243,407,608
Ensembl chr 2:243,366,181...243,407,608 		JBrowse link
G Mybph myosin binding protein H IAGP DNA:missense mutations:cds:p.I?T, p.R?K (rat) RGD PMID:23460292 RGD:12802369 NCBI chr13:51,034,228...51,041,903
Ensembl chr13:51,034,256...51,041,902 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:27292124 NCBI chr 8:128,022,512...128,027,462
Ensembl chr 8:128,022,473...128,026,841 		JBrowse link
G Myh7 myosin heavy chain 7 IEP
ISO		 protein:decreased expression:heart left ventricle, arteriole
CTD Direct Evidence: marker/mechanism		 CTD PMID:32147540, PMID:9686760 RGD:9835388 NCBI chr15:33,605,769...33,657,761
Ensembl chr15:33,634,422...33,656,089 		JBrowse link
G Myo6 myosin VI IDA protein:altered localization:renal proximal tubule, microvillus RGD PMID:16107581 RGD:2314963 NCBI chr 8:87,583,649...87,731,271
Ensembl chr 8:87,630,916...87,731,269 		JBrowse link
G Myod1 myogenic differentiation 1 IEP mRNA:decreased expression:gastrocnemius RGD PMID:22076133 RGD:9686076 NCBI chr 1:102,396,538...102,399,248
Ensembl chr 1:102,396,538...102,399,248 		JBrowse link
G Ncf1 neutrophil cytosolic factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16331104 PMID:17324946 PMID:19018797 PMID:32165127 NCBI chr12:25,497,104...25,506,300
Ensembl chr12:25,497,104...25,506,300 		JBrowse link
G Ncf2 neutrophil cytosolic factor 2 IEP protein:increased expression:heart left ventricle RGD PMID:19307699 RGD:2314430 NCBI chr13:70,226,441...70,259,019
Ensembl chr13:70,226,647...70,257,576 		JBrowse link
G Nedd4l NEDD4 like E3 ubiquitin protein ligase ISO CTD Direct Evidence: marker/mechanism CTD PMID:18524855 PMID:23348737 NCBI chr18:60,392,376...60,719,720
Ensembl chr18:60,392,376...60,719,720 		JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 treatment IEP
ISO		 CTD Direct Evidence: marker/mechanism CTD PMID:32165127, PMID:23775684 RGD:10412717 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996 		JBrowse link
G Nfkbia NFKB inhibitor alpha treatment IEP RGD PMID:19246475 RGD:7495780 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457 		JBrowse link
G Ngf nerve growth factor IEP RGD PMID:10797303 RGD:5144109 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453 		JBrowse link
G Ngfr nerve growth factor receptor IAGP DNA,protein:missense mutation:CDS:c.28G>A, p.A10T (rat strains: SHR/Izm, SHRSP/Izm, WKHT) RGD PMID:8762194 RGD:5508800 NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061 		JBrowse link
G Nisch nischarin IMP RGD PMID:12021582 RGD:1581128 NCBI chr16:7,254,372...7,290,670
Ensembl chr16:7,254,974...7,290,561 		JBrowse link
G Nos1 nitric oxide synthase 1 treatment IEP
IDA
IMP		 mRNA:decreased expression:bladder, penis RGD PMID:17574276, PMID:23201071, PMID:15913838, PMID:16093913, PMID:15775788, PMID:20494920 RGD:1642127, RGD:7257668, RGD:1581142, RGD:1581141, RGD:1581143, RGD:5132600 NCBI chr12:44,214,949...44,405,530
Ensembl chr12:44,213,943...44,520,341 		JBrowse link
G Nos2 nitric oxide synthase 2 IEP
ISO		 protein:increased expression, increased activity:kidney
CTD Direct Evidence: marker/mechanism		 CTD PMID:18605955 PMID:25101153 PMID:27292124, PMID:15773227, PMID:11702222 RGD:1580264, RGD:1298023 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190 		JBrowse link
G Nos3 nitric oxide synthase 3 treatment
no_association		 IEP
IDA
ISO		 associated with Pregnancy Complications
CTD Direct Evidence: marker/mechanism|therapeutic
DNA:duplication, snp:intron, cds:IVS4?-?+27, p.E298D (human)
DNA:snp:cds:p.E298D (human)
protein:decreased phosphorylation:brain		 CTD PMID:11457755 PMID:12947532 PMID:16331104 PMID:19008412 PMID:19407804, PMID:18047920, PMID:29285068, PMID:29084084, PMID:10981549, PMID:11882615, PMID:9674630, PMID:20813549 RGD:2292113, RGD:13504683, RGD:13446414, RGD:1580278, RGD:1580271, RGD:1580282, RGD:4891993 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410 		JBrowse link
G Nox4 NADPH oxidase 4 IEP
ISO
IMP		 protein:increased expression:aorta, vascular associated smooth muscle cell
CTD Direct Evidence: marker/mechanism		 CTD PMID:27659729 PMID:27847271 PMID:32147540, PMID:18418428, PMID:26644237 RGD:2324669, RGD:11085830 NCBI chr 1:150,796,359...150,976,186
Ensembl chr 1:150,797,084...150,976,194 		JBrowse link
G Nppa natriuretic peptide A IEP
ISO		 protein:increased expression:plasma:
CTD Direct Evidence: marker/mechanism|therapeutic		 CTD PMID:2526952 PMID:7839143 PMID:8188982 PMID:9869009 PMID:12940879 PMID:19219041 PMID:24039778 PMID:32147540, PMID:20139323 RGD:7248593 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705 		JBrowse link
G Nppb natriuretic peptide B treatment
susceptibility		 IEP
ISO
IDA		 CTD Direct Evidence: marker/mechanism|therapeutic
DNA:repeats		 CTD PMID:9194512 PMID:19219041 PMID:24039778 PMID:30310171 PMID:32147540, PMID:11897768, PMID:21403100, PMID:17554401 RGD:70484, RGD:5685657, RGD:1642191 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531 		JBrowse link
G Nppc natriuretic peptide C severity ISO associated with Pregnancy Complications;protein:increased expression:plasma RGD PMID:11775888, PMID:12452325 RGD:1642292, RGD:1580150 NCBI chr 9:93,731,436...93,735,636
Ensembl chr 9:93,731,436...93,735,636 		JBrowse link
G Npr1 natriuretic peptide receptor 1 IAGP
ISO		 DNA:repeat:promoter: (rat)
CTD Direct Evidence: marker/mechanism		 CTD PMID:20881240, PMID:12511524 RGD:628585 NCBI chr 2:189,840,403...189,857,032
Ensembl chr 2:189,840,403...189,856,090 		JBrowse link
G Npr3 natriuretic peptide receptor 3 ISO DNA:snp:promoter:g.-55C>A (human) RGD PMID:12872042 RGD:1580175 NCBI chr 2:61,883,946...61,950,291
Ensembl chr 2:61,888,950...61,949,926 		JBrowse link
G Nptn neuroplastin ISO CTD Direct Evidence: marker/mechanism CTD PMID:22228705 NCBI chr 8:63,379,062...63,445,694
Ensembl chr 8:63,379,087...63,445,686 		JBrowse link
G Npy neuropeptide Y IMP
IEP
ISO		 DNA:missense mutation:cds:p.L7P (human) RGD PMID:15699473, PMID:18835922, PMID:11689216 RGD:1357410, RGD:10448968, RGD:1580177 NCBI chr 4:79,557,856...79,565,059
Ensembl chr 4:79,557,854...79,565,097 		JBrowse link
G Npy1r neuropeptide Y receptor Y1 IMP RGD PMID:15699473 RGD:1357410 NCBI chr16:24,779,480...24,789,131
Ensembl chr16:24,779,477...24,788,740 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 treatment IDA RGD PMID:21502369 RGD:11035215 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180 		JBrowse link
G Nr2f2 nuclear receptor subfamily 2, group F, member 2 IMP RGD PMID:25687237 RGD:10401852 NCBI chr 1:131,447,671...131,465,749
Ensembl chr 1:131,448,447...131,460,473 		JBrowse link
G Nr2f2em1Mcwi nuclear receptor subfamily 2, group F, member 2; zinc finger nuclease induced mutant 1, Medical College of Wisconsin IMP RGD PMID:25687237 RGD:10401852
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 IMP
ISO		 associated with fetal nutrition disorder
CTD Direct Evidence: marker/mechanism		 CTD PMID:18434569 PMID:20659135, PMID:20674672, PMID:20659135 RGD:4892208, RGD:7174714 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647 		JBrowse link
G Nudt1 nudix hydrolase 1 IEP RGD PMID:17280880 RGD:10449166 NCBI chr12:16,391,578...16,398,771
Ensembl chr12:16,391,578...16,395,029 		JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 IEP
ISO		 mRNA:increased expression:aorta (rat)
CTD Direct Evidence: marker/mechanism		 CTD PMID:22352330, PMID:9494115 RGD:633385 NCBI chr 4:163,239,853...163,261,937
Ensembl chr 4:163,239,849...163,261,958 		JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase IEP protein:increased expression:heart left ventricle (rat) RGD PMID:24388463 RGD:7800726 NCBI chr11:74,717,600...74,793,902
Ensembl chr11:74,720,254...74,793,803 		JBrowse link
G Orai1 ORAI calcium release-activated calcium modulator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19897708 NCBI chr12:38,981,903...38,995,570
Ensembl chr12:38,981,927...38,995,570 		JBrowse link
G Oxsr1 oxidative stress responsive kinase 1 ISO CTD Direct Evidence: therapeutic CTD PMID:22949526 NCBI chr 8:127,920,349...128,009,951
Ensembl chr 8:127,920,349...128,009,951 		JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide IMP
ISO
IEP		 CTD Direct Evidence: therapeutic
mRNA:decreased expression:paraventricular hypothalamic nucleus 		CTD PMID:9334988 PMID:18562099, PMID:18562099, PMID:16157794 RGD:2304105, RGD:2304174 NCBI chr 3:123,106,694...123,107,534
Ensembl chr 3:123,106,694...123,107,534 		JBrowse link
G Oxtr oxytocin receptor IEP mRNA:decreased expression:brainstem RGD PMID:16157794 RGD:2304174 NCBI chr 4:144,399,326...144,417,598
Ensembl chr 4:144,403,358...144,416,116 		JBrowse link
G Pappa1 pappalysin 1 ISO associated with Pregnancy Complications, Cardiovascular;protein:decreased expression:serum RGD PMID:12224070 RGD:1642331 NCBI chr 5:80,919,932...81,153,904
Ensembl chr 5:80,920,568...81,150,940 		JBrowse link
G Pdgfb platelet derived growth factor subunit B IEP RGD PMID:8869081 RGD:10449484 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha IEP RGD PMID:1657776 RGD:11080972 NCBI chr14:35,527,926...35,581,130
Ensembl chr14:35,527,927...35,581,031 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta IEP protein:increased tyrosine phosphorylation:glomerulus RGD PMID:12047046, PMID:1657776 RGD:2292214, RGD:11080972 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381 		JBrowse link
G Pgf placental growth factor ISO associated with Pregnancy Complications, Cardiovascular;mRNA:decreased expression:placenta RGD PMID:12808329 RGD:1642387 NCBI chr 6:108,994,016...109,004,598
Ensembl chr 6:108,994,018...109,004,598 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 IEP
IMP		 protein:decreased expression:ventricular myocyte (rat) RGD PMID:18300869, PMID:19015400 RGD:4108492, RGD:4108483 NCBI chr 2:31,742,326...31,826,882
Ensembl chr 2:31,745,088...31,826,867 		JBrowse link
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 ISO RGD PMID:21810655 RGD:8693428 NCBI chr 8:21,669,236...21,680,615
Ensembl chr 8:21,669,236...21,680,615 		JBrowse link
G Pkd1 polycystin 1, transient receptor potential channel interacting ISO ClinVar Annotator: match by term: Hypertension ClinVar PMID:11115377 PMID:12482949 PMID:16430766 PMID:17574468 PMID:17582161 PMID:22508176 PMID:23064367 PMID:23431072 PMID:23760289 PMID:24694054 PMID:25741868 PMID:26467025 PMID:26632257 PMID:26950445 PMID:27499327 PMID:29801666 PMID:30333007 PMID:31056860 PMID:31738409 PMID:32203225 NCBI chr10:13,914,057...13,962,008
Ensembl chr10:13,915,214...13,962,008 		JBrowse link
G Plat plasminogen activator, tissue type ISO CTD Direct Evidence: marker/mechanism CTD PMID:22352330 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889 		JBrowse link
G Plcd1 phospholipase C, delta 1 IEP
IDA		 protein:increased expression:aorta, arteriole, glomerulus
protein:increased activity:aorta		 RGD PMID:17198910, PMID:1313006 RGD:2300421, RGD:2300423 NCBI chr 8:127,753,514...127,782,070
Ensembl chr 8:127,753,539...127,782,070 		JBrowse link
G Plekha7 pleckstrin homology domain containing A7 IMP RGD PMID:25136115 RGD:11079199 NCBI chr 1:185,427,600...185,493,985
Ensembl chr 1:185,356,975...185,538,694 		JBrowse link
G Plekha7em4Mcwi pleckstrin homology domain containing, family A member 7; zinc finger nuclease induced mutant 4, Medical College of Wisconsin ameliorates IMP RGD PMID:25136115, PMID:25136115 RGD:11079199, RGD:11079199
G Plg plasminogen ISO CTD Direct Evidence: marker/mechanism CTD PMID:6383834 NCBI chr 1:48,521,828...48,563,895
Ensembl chr 1:48,521,772...48,563,776 		JBrowse link
G Pnmt phenylethanolamine-N-methyltransferase no_association ISO
IEP		 DNA:snps:5' utr:g.-390G>A, g.-184G>A rs876493 (human)
protein:decreased activity:adrenal gland (rat)
DNA:snp:5' utr:g.-390G>A (human)		 RGD PMID:17645789, PMID:20378607, PMID:14553966 RGD:5130172, RGD:5130152, RGD:5130164 NCBI chr10:86,340,893...86,342,501
Ensembl chr10:86,340,940...86,342,858 		JBrowse link
G Pomc proopiomelanocortin ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:76749 PMID:187612 PMID:216942 PMID:323586 PMID:1316127 PMID:1321011 PMID:1321309 PMID:1327015 PMID:1330390 PMID:1334993 PMID:1649024 PMID:1664305 PMID:2157753 PMID:2455169 PMID:2551692 PMID:2821097 PMID:2822310 PMID:2849322 PMID:2992854 PMID:3001556 PMID:3015460 PMID:4367732 PMID:6088243 PMID:6089027 PMID:6097376 PMID:6100240 PMID:6135010 PMID:6143199 PMID:6254450 PMID:6274577 PMID:6279500 PMID:6283272 PMID:8136112 PMID:8261660 PMID:8279378 PMID:8713685 PMID:8800598 PMID:9056691 PMID:9535146 PMID:10100081 PMID:10474778 PMID:10513829 PMID:10658937 PMID:11071300 PMID:11071304 PMID:11132610 PMID:11193135 PMID:11518849 PMID:11560123 PMID:11703388 PMID:12872045 PMID:12887135 PMID:15110907 PMID:15132301 PMID:15554453 PMID:16053986 PMID:16243970 PMID:16546835 PMID:16620303 PMID:17324744 PMID:17954371 PMID:17994356 PMID:18067589 PMID:18487447 PMID:19153526 PMID:19458537 PMID:20186125 PMID:20659135 NCBI chr 6:28,382,937...28,388,771
Ensembl chr 6:28,382,962...28,388,967 		JBrowse link
G Postn periostin IEP associated with Renal Insufficiency, Chronic; protein:increased expression:left ventricle: RGD PMID:21712488 RGD:10041050 NCBI chr 2:143,656,820...143,688,087
Ensembl chr 2:143,656,793...143,688,087 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha treatment IEP
ISO
IMP		 mRNA:increased expression:skeletal muscle
CTD Direct Evidence: marker/mechanism|therapeutic		 CTD PMID:16054168 PMID:19834340, PMID:19763017, PMID:15967866 RGD:2313778, RGD:1580222 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma IMP
ISO
IEP
IDA		 CTD Direct Evidence: marker/mechanism|therapeutic
protein:decreased expression:rostral ventrolateral medulla (rat)
human gene in a mouse model		 CTD PMID:15199296 PMID:19666838 PMID:27292124, PMID:18437150, PMID:20404217, PMID:18316027, PMID:12923396, PMID:15970297 RGD:2301888, RGD:7175297, RGD:2301864, RGD:1580690, RGD:1580684 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380 		JBrowse link
G Ppbp pro-platelet basic protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:6192689 PMID:15513305 NCBI chr14:18,852,433...18,853,237
Ensembl chr14:18,851,954...18,853,315 		JBrowse link
G Prkag2 protein kinase AMP-activated non-catalytic subunit gamma 2 ISO ClinVar Annotator: match by term: High blood pressure ClinVar PMID:25741868 PMID:28492532 NCBI chr 4:6,559,153...6,799,888
Ensembl chr 4:6,559,545...6,799,632 		JBrowse link
G Prkar1b protein kinase cAMP-dependent type I regulatory subunit beta ISO RGD PMID:11161799 RGD:619653 NCBI chr12:17,614,536...17,713,567
Ensembl chr12:17,614,632...17,712,373 		JBrowse link
G Prkca protein kinase C, alpha IAGP RGD PMID:15792354 RGD:1581271 NCBI chr10:96,186,509...96,585,168
Ensembl chr10:96,191,133...96,584,947 		JBrowse link
G Prkcb protein kinase C, beta IDA RGD PMID:15804434 RGD:1625513 NCBI chr 1:192,233,569...192,575,339
Ensembl chr 1:192,233,910...192,574,831 		JBrowse link
G Prkcd protein kinase C, delta IEP
ISO
IAGP		 protein:increased expression:heart, fibroblast
CTD Direct Evidence: marker/mechanism		 CTD PMID:23973649, PMID:10756122, PMID:15792354 RGD:1642534, RGD:1581271 NCBI chr16:6,655,131...6,675,746
Ensembl chr16:6,655,120...6,675,746 		JBrowse link
G Prkce protein kinase C, epsilon IAGP RGD PMID:15792354 RGD:1581271 NCBI chr 6:9,483,400...9,973,396
Ensembl chr 6:9,790,422...9,973,396 		JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 IEP mRNA, protein:splice variant, alternative form:basilar artery RGD PMID:14512447 RGD:7775067 NCBI chr 1:248,982,039...250,300,952 JBrowse link
G Prlhr prolactin releasing hormone receptor ISO DNA:SNP, missense mutation:promoter, cds:-62G>A, 914C>T (p.P305L) (human) RGD PMID:14691196 RGD:1641832 NCBI chr 1:281,754,472...281,756,159
Ensembl chr 1:281,754,724...281,756,159 		JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa ISO CTD Direct Evidence: marker/mechanism CTD PMID:22352330 NCBI chr18:24,918,402...24,928,822
Ensembl chr18:24,918,398...24,929,091 		JBrowse link
G Pten phosphatase and tensin homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:15646324 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832 		JBrowse link
G Ptgds prostaglandin D2 synthase ISO protein:increased expression:serum, urine RGD PMID:11882588 RGD:1642584 NCBI chr 3:2,686,125...2,689,059
Ensembl chr 3:2,686,123...2,689,084 		JBrowse link
G Ptgis prostaglandin I2 synthase ISO RGD PMID:12372404 RGD:1298040 NCBI chr 3:163,950,746...163,986,129 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IAGP
ISO		 CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:14757778 PMID:15834289 PMID:20667508 PMID:22349312, PMID:15775781, PMID:16467505 RGD:1581285, RGD:1580671 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335 		JBrowse link
G Pth parathyroid hormone ISO protein:increased expression:serum (human)
CTD Direct Evidence: marker/mechanism		 CTD PMID:1930854, PMID:23460043 RGD:7242420 NCBI chr 1:178,215,829...178,218,761
Ensembl chr 1:178,215,829...178,218,761 		JBrowse link
G Ptk2 protein tyrosine kinase 2 IAGP
IEP		 protein:increased expression:aorta RGD PMID:12732587, PMID:21068519 RGD:729831, RGD:10041072 NCBI chr 7:114,436,419...114,611,317
Ensembl chr 7:114,437,361...114,590,119 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta susceptibility ISO
IEP		 DNA:polymorphism:promoter:-22A>G
protein:increased expression:aorta		 RGD PMID:18075463, PMID:21068519 RGD:2292575, RGD:10041072 NCBI chr15:42,827,306...42,947,796
Ensembl chr15:42,827,310...42,947,656 		JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 ISO CTD Direct Evidence: therapeutic CTD PMID:28899902 NCBI chr 3:164,665,462...164,711,936
Ensembl chr 3:164,665,532...164,711,848 		JBrowse link
G Ptprj protein tyrosine phosphatase, receptor type, J IAGP RGD PMID:15710778 RGD:1357414 NCBI chr 3:79,233,519...79,390,956
Ensembl chr 3:79,233,525...79,390,956 		JBrowse link
G Ptpru protein tyrosine phosphatase, receptor type, U susceptibility ISO RGD PMID:11086029 RGD:1642652 NCBI chr 5:149,922,374...149,996,352
Ensembl chr 5:149,922,352...149,996,334 		JBrowse link
G Qdpr quinoid dihydropteridine reductase IEP protein:decreased expression:aorta smooth muscle (rat) RGD PMID:19743417 RGD:5128580 NCBI chr14:70,164,682...70,178,284
Ensembl chr14:70,164,650...70,178,284 		JBrowse link
G Rad51 RAD51 recombinase IDA RGD PMID:24239235 RGD:8693672 NCBI chr 3:110,918,240...110,942,920
Ensembl chr 3:110,918,243...110,942,917 		JBrowse link
G Rag1 recombination activating 1 IMP RGD PMID:23364523 RGD:7207429 NCBI chr 3:91,206,394...91,217,491
Ensembl chr 3:91,206,394...91,217,491 		JBrowse link
G Ralbp1 ralA binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23821548 NCBI chr 9:113,579,107...113,598,477
Ensembl chr 9:113,579,107...113,598,480 		JBrowse link
G Ramp2 receptor activity modifying protein 2 susceptibility ISO
IEP		 DNA:SNP:intron
associated with Pregnancy Complications
mRNA, protein:increased expression:heart myocardium, aorta		 RGD PMID:15797661, PMID:11600589, PMID:16450076 RGD:1642679, RGD:1642682, RGD:1625300 NCBI chr10:89,166,170...89,168,962
Ensembl chr10:89,166,890...89,168,965 		JBrowse link
G Rasgrp3 RAS guanyl releasing protein 3 ISO RGD PMID:19421330 RGD:2314812 NCBI chr 6:21,072,634...21,171,619
Ensembl chr 6:21,072,634...21,135,880 		JBrowse link
G Reg3g regenerating family member 3 gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:27798352 NCBI chr 4:109,529,679...109,532,234
Ensembl chr 4:109,529,679...109,532,234 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit IEP
ISO		 CTD Direct Evidence: marker/mechanism CTD PMID:19018797 PMID:27659729 PMID:32147540, PMID:16840655 RGD:2298761 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249 		JBrowse link
G Ren renin IDA
ISO		 CTD Direct Evidence: marker/mechanism
protein:decreased activity:plasma (mouse)		 CTD PMID:45830 PMID:62162 PMID:998518 PMID:1071603 PMID:1149188 PMID:6381767 PMID:7721401 PMID:11501062 PMID:12414515 PMID:12600921 PMID:17537837 PMID:18679781 PMID:18847324 PMID:19770776 PMID:20429690 PMID:20811386 PMID:21393355, PMID:16467505, PMID:22493079, PMID:22681982, PMID:16138564 RGD:1580671, RGD:6892655, RGD:6784501, RGD:1580697 NCBI chr13:50,502,724...50,513,953
Ensembl chr13:50,502,724...50,514,151 		JBrowse link
G Resp18 regulated endocrine-specific protein 18 IMP RGD PMID:29570433 RGD:14348960 NCBI chr 9:82,470,794...82,477,136
Ensembl chr 9:82,470,759...82,477,181 		JBrowse link
G Resp18em2Mcwi regulated endocrine-specific protein 18; zinc finger nuclease induced mutant 2, Medical College of Wisconsin IMP RGD PMID:29570433 RGD:14348960
G Retn resistin ISO DNA:SNP:3' utr:*62A>G (human) RGD PMID:12629116 RGD:1624968 NCBI chr12:2,201,909...2,203,649
Ensembl chr12:2,201,891...2,204,249 		JBrowse link
G Rffl ring finger and FYVE-like domain containing E3 ubiquitin protein ligase IEP mRNA,protein:increased expression:heart RGD PMID:21357277 RGD:13442502 NCBI chr10:70,157,621...70,220,618
Ensembl chr10:70,157,621...70,220,582 		JBrowse link
G Rgs2 regulator of G-protein signaling 2 ISO
IEP		 CTD Direct Evidence: therapeutic CTD PMID:1798635, PMID:14608379, PMID:17986358 RGD:13524579, RGD:2289116 NCBI chr13:60,846,458...60,849,061
Ensembl chr13:60,846,308...60,849,094 		JBrowse link
G Rgs4 regulator of G-protein signaling 4 treatment IEP RGD PMID:21825230 RGD:7207400 NCBI chr13:88,054,817...88,061,108
Ensembl chr13:88,054,817...88,061,108 		JBrowse link
G Rgs5 regulator of G-protein signaling 5 treatment ISO
IEP		 CTD Direct Evidence: therapeutic CTD PMID:1798635, PMID:21825230 RGD:7207400 NCBI chr13:87,966,820...88,002,831
Ensembl chr13:87,966,758...88,003,035 		JBrowse link
G Rhoa ras homolog family member A IEP protein:altered localization:mesenteric artery RGD PMID:17620967 RGD:1642801 NCBI chr 8:117,082,440...117,116,244
Ensembl chr 8:117,106,576...117,116,167 		JBrowse link
G Rnls renalase, FAD-dependent amine oxidase ISO associated with Diabetes Mellitus Type 2; DNA:SNPs: : rs2296545,rs2576178 (human)
associated with kidney Failure,Chronic;DNA:SNPs: : rs2576178, rs10887800 (human)		 RGD PMID:21964580, PMID:21178975, PMID:21617193 RGD:7327172, RGD:7327174, RGD:7327173 NCBI chr 1:251,828,285...252,101,963
Ensembl chr 1:251,828,290...252,100,759 		JBrowse link
G Rnpep arginyl aminopeptidase IEP
IMP		 protein:increased expression:adrenal gland, neurohypophysis RGD PMID:9660082, PMID:3001599 RGD:2325942, RGD:2325950 NCBI chr13:52,092,863...52,124,006
Ensembl chr13:52,092,859...52,111,363 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19289642 NCBI chr10:73,824,200...73,865,503
Ensembl chr10:73,824,202...73,865,364 		JBrowse link
G RT1-Ba RT1 class II, locus Ba ISO DNA:polymorphisms (human) RGD PMID:11798899 RGD:5147807 NCBI chr20:4,066,133...4,070,726
Ensembl chr20:4,066,132...4,070,721 		JBrowse link
G S100b S100 calcium binding protein B ISO protein:increased expression:serum RGD PMID:21130083 RGD:5508770 NCBI chr20:13,130,633...13,142,856
Ensembl chr20:13,130,636...13,142,856 		JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 disease_progression IAGP associated with SHRSP;mRNA,protein:increased expression, decreased expression:kidney (rat) RGD PMID:17938382 RGD:1643008 NCBI chr 2:218,654,406...218,658,761
Ensembl chr 2:218,654,554...218,658,761 		JBrowse link
G Scnn1a sodium channel epithelial 1 subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:11752024 PMID:23348737 NCBI chr 4:157,834,339...157,860,472
Ensembl chr 4:157,836,912...157,860,049 		JBrowse link
G Scnn1b sodium channel epithelial 1 subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:15174897 PMID:15198480 PMID:19344079 NCBI chr 1:191,829,547...191,883,991
Ensembl chr 1:191,829,555...191,884,298 		JBrowse link
G Scnn1g sodium channel epithelial 1 subunit gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:15198480 NCBI chr 1:191,704,397...191,738,271
Ensembl chr 1:191,704,311...191,738,268 		JBrowse link
G Selp selectin P ISO CTD Direct Evidence: marker/mechanism CTD PMID:15513305 NCBI chr13:82,428,914...82,464,629
Ensembl chr13:82,429,063...82,464,628 		JBrowse link
G Serpina1 serpin family A member 1 ISO protein:increased expression:urine RGD PMID:10353322 RGD:1643147 NCBI chr 6:127,610,241...127,632,265
Ensembl chr 6:127,610,243...127,632,265 		JBrowse link
G Serpine1 serpin family E member 1 treatment ISO
IEP
IDA		 protein:increased expression:plasma (human)
mRNA:increased expression:kidney (SHRSP/A3N rat)
CTD Direct Evidence: marker/mechanism		 CTD PMID:21051829 PMID:22352330, PMID:8355419, PMID:11907153, PMID:16645728 RGD:8547753, RGD:28912746, RGD:11081003 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482 		JBrowse link
G Serpine2 serpin family E member 2 IEP mRNA, protein:increased expression:blood vessel RGD PMID:12524238 RGD:729767 NCBI chr 9:85,560,852...85,629,410
Ensembl chr 9:85,560,863...85,626,094 		JBrowse link
G Serpinf2 serpin family F member 2 ISO RGD PMID:9361364 RGD:1625531 NCBI chr10:62,264,247...62,272,353
Ensembl chr10:62,264,788...62,273,119 		JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 no_association
susceptibility		 ISO DNA:snps:exon, intron: (human) RGD PMID:15304560, PMID:16221215 RGD:1580969, RGD:1580968 NCBI chr 1:24,185,451...24,302,309
Ensembl chr 1:24,185,435...24,302,298 		JBrowse link
G Sh2b3 SH2B adaptor protein 3 IMP RGD PMID:25776069 RGD:13442483 NCBI chr12:40,261,990...40,265,757
Ensembl chr12:40,244,081...40,265,757 		JBrowse link
G Sh2b3em1Mcwi SH2B adaptor protein 3; zinc finger nuclease induced mutant 1, Medical College of Wisconsin IMP RGD PMID:25776069 RGD:13442483
G Slc12a2 solute carrier family 12 member 2 IEP
ISO
IDA		 mRNA:increased expression:aorta
CTD Direct Evidence: marker/mechanism		 CTD PMID:17259435, PMID:15020309, PMID:21814290 RGD:1580582, RGD:9587757 NCBI chr18:52,917,124...52,985,281
Ensembl chr18:52,917,124...52,985,261 		JBrowse link
G Slc12a3 solute carrier family 12 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18480177 NCBI chr19:11,106,033...11,144,674
Ensembl chr19:11,106,033...11,144,641 		JBrowse link
G Slc26a4 solute carrier family 26 member 4 ISO RGD PMID:17120771 RGD:7411553 NCBI chr 6:50,809,103...50,848,443
Ensembl chr 6:50,808,923...50,846,965 		JBrowse link
G Slc2a1 solute carrier family 2 member 1 IEP protein:increased expression:renal glomerulus RGD PMID:12771048 RGD:12879474 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897 		JBrowse link
G Slc2a3 solute carrier family 2 member 3 IEP protein:decreased expression:hippocampus, parietal cortex; protein:increased expression:hypothalamus, thalamus RGD PMID:7598707 RGD:1642812 NCBI chr 4:155,549,991...155,626,018
Ensembl chr 4:155,408,233...155,631,856 		JBrowse link
G Slc34a1 solute carrier family 34 member 1 ISO ClinVar Annotator: match by term: High blood pressure ClinVar PMID:16638441 PMID:25741868 NCBI chr17:9,747,766...9,762,739
Ensembl chr17:9,747,752...9,762,813 		JBrowse link
G Slc4a4 solute carrier family 4 member 4 IEP protein:increased expression:kidney cortex RGD PMID:15340004 RGD:1600028 NCBI chr14:20,476,258...20,817,042
Ensembl chr14:20,479,323...20,920,286 		JBrowse link
G Slc5a2 solute carrier family 5 member 2 IDA RGD PMID:14506074 RGD:1599050 NCBI chr 1:199,682,688...199,688,809
Ensembl chr 1:199,682,688...199,688,809 		JBrowse link
G Slc6a18 solute carrier family 6 member 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15121838 NCBI chr 1:32,221,679...32,235,599
Ensembl chr 1:32,221,636...32,236,051 		JBrowse link
G Slc6a19 solute carrier family 6 member 19 IEP mRNA:increased expression RGD PMID:17264310 RGD:1600036 NCBI chr 1:32,199,869...32,218,628
Ensembl chr 1:32,199,810...32,220,045 		JBrowse link
G Slc6a2 solute carrier family 6 member 2 ISO DNA:polymorphism:1287G>A
CTD Direct Evidence: marker/mechanism		 CTD PMID:22533655, PMID:17124432 RGD:1624279 NCBI chr19:15,391,682...15,431,274
Ensembl chr19:15,391,581...15,431,274 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 IEP protein:increased expression:caudate-putamen RGD PMID:9074541 RGD:1625656 NCBI chr 1:32,323,011...32,363,983
Ensembl chr 1:32,321,580...32,363,983 		JBrowse link
G Slc8a1 solute carrier family 8 member A1 IEP
ISO		 DNA:snps:intron:g.-23200T>C, g.-23181T>C (human)
DNA:SNP: :1784C>T		 RGD PMID:16343576, PMID:15785003, PMID:15824464 RGD:1598724, RGD:1580732, RGD:1580586 NCBI chr 6:4,244,076...4,564,262
Ensembl chr 6:4,258,991...4,520,604 		JBrowse link
G Slc9a3 solute carrier family 9 member A3 IDA RGD PMID:11880335, PMID:12372791 RGD:737665, RGD:727447 NCBI chr 1:31,731,652...31,777,144
Ensembl chr 1:31,734,327...31,777,070 		JBrowse link
G Slc9a3r1 SLC9A3 regulator 1 IEP RGD PMID:15311100 RGD:1580741 NCBI chr10:103,713,045...103,730,145
Ensembl chr10:103,713,045...103,730,145 		JBrowse link
G Slc9a3r2 SLC9A3 regulator 2 IEP
ISO		 CTD Direct Evidence: marker/mechanism CTD PMID:22228705, PMID:15311100 RGD:1580741 NCBI chr10:14,003,330...14,015,066
Ensembl chr10:14,003,320...14,013,870 		JBrowse link
G Sod1 superoxide dismutase 1 treatment ISO
IEP		 associated with Hydronephrosis
CTD Direct Evidence: marker/mechanism|therapeutic
human gene in a rat model
mRNA:decreased expression:rostral ventrolateral medulla (rat)		 CTD PMID:9024144 PMID:25101153 PMID:32165127, PMID:19403858, PMID:16716903, PMID:16864745, PMID:16716903, PMID:17198913 RGD:2312366, RGD:1580833, RGD:1581232, RGD:1580833, RGD:1600704 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862 		JBrowse link
G Sod2 superoxide dismutase 2 IDA
ISO		 CTD Direct Evidence: marker/mechanism CTD PMID:11834524 PMID:21593737 PMID:25101153, PMID:16716903 RGD:1580833 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587 		JBrowse link
G Sod3 superoxide dismutase 3 IDA
ISO		 CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:16864745 PMID:17023265, PMID:12600899, PMID:16864745 RGD:1580845, RGD:1581232 NCBI chr14:60,958,583...60,971,143
Ensembl chr14:60,958,592...60,964,324 		JBrowse link
G Sqstm1 sequestosome 1 IEP protein:decreased expression:brain RGD PMID:23499735 RGD:11561939 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase IDA RGD PMID:16157790 RGD:1601372 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642 		JBrowse link
G Srf serum response factor IDA RGD PMID:16822834 RGD:1580749 NCBI chr 9:16,737,637...16,747,226
Ensembl chr 9:16,737,642...16,747,225 		JBrowse link
G Sst somatostatin IEP protein:altered expression:stomach RGD PMID:17928643 RGD:2303191 NCBI chr11:80,358,172...80,359,449
Ensembl chr11:80,358,211...80,359,444 		JBrowse link
G Stim1 stromal interaction molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19897708 NCBI chr 1:167,373,894...167,533,412
Ensembl chr 1:167,373,678...167,533,420 		JBrowse link
G Stk11 serine/threonine kinase 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19289642 NCBI chr 7:12,440,751...12,457,513
Ensembl chr 7:12,440,751...12,457,513 		JBrowse link
G Stk39 serine threonine kinase 39 ISO CTD Direct Evidence: therapeutic CTD PMID:22949526 NCBI chr 3:54,359,449...54,625,702
Ensembl chr 3:54,359,451...54,625,414 		JBrowse link
G Sts steroid sulfatase IEP protein:increased expression:multiple organs RGD PMID:8539776 RGD:1601393 NCBI chr  X:45,420,418...45,428,748
Ensembl chr  X:45,420,596...45,428,750 		JBrowse link
G Tac3 tachykinin precursor 3 IEP protein:increased expression:supraoptic nucleus, medulla oblongata RGD PMID:2478257 RGD:2305983 NCBI chr 7:71,023,976...71,030,582
Ensembl chr 7:71,023,976...71,030,582 		JBrowse link
G Tacr1 tachykinin receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21294877 NCBI chr 4:113,247,236...113,416,139
Ensembl chr 4:113,247,795...113,414,504 		JBrowse link
G Tacr3 tachykinin receptor 3 IDA RGD PMID:2471579 RGD:2305984 NCBI chr 2:240,021,152...240,118,971
Ensembl chr 2:240,021,152...240,118,971 		JBrowse link
G Tbxas1 thromboxane A synthase 1 IDA associated with hyperinsulinism RGD PMID:9370383, PMID:16192456 RGD:1601472, RGD:1601439 NCBI chr 4:66,624,181...66,846,745
Ensembl chr 4:66,670,618...66,846,805 		JBrowse link
G Tf transferrin ISO protein:decreased expression RGD PMID:14974364 RGD:1601524 NCBI chr 8:111,694,570...111,721,275
Ensembl chr 8:111,673,547...111,721,333 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 IEP
IAGP
ISO		 protein:increased expression:vascular associated smooth muscle cell
mRNA:increased expression:kidney (SHRSP/A3N rat)
protein:increased expression:renal glomerulus
CTD Direct Evidence: marker/mechanism		 CTD PMID:11682445 PMID:19018797, PMID:17364610, PMID:11907153, PMID:11682445, PMID:12771048, PMID:15118671 RGD:1601552, RGD:28912746, RGD:30296650, RGD:12879474, RGD:1331525 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199 		JBrowse link
G Tgfb3 transforming growth factor, beta 3 no_association ISO DNA:polymorphism, SNPs RGD PMID:15924806 RGD:1625704 NCBI chr 6:109,913,757...109,936,217
Ensembl chr 6:109,913,757...109,935,533 		JBrowse link
G Tgm2 transglutaminase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17898543 NCBI chr 3:154,597,165...154,627,257
Ensembl chr 3:154,597,168...154,627,257 		JBrowse link
G Th tyrosine hydroxylase susceptibility IEP
ISO		 mRNA:increased expression:brain
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:intron:g.1090T>C rs2070762 (human)		 CTD PMID:27659729 PMID:32147540 PMID:32165127, PMID:16650497, PMID:16636198 RGD:1601630, RGD:1601631 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287 		JBrowse link
G Thbd thrombomodulin treatment IEP
ISO		 associated with Experimental Diabetes Mellitus
protein:increased expression:plasma
protein:decreased expression:plasma		 RGD PMID:14737039, PMID:16095049, PMID:17401180, PMID:12611420 RGD:1601646, RGD:5685017, RGD:1601636, RGD:1601652 NCBI chr 3:142,748,673...142,752,325
Ensembl chr 3:142,748,674...142,752,325 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 ISO
IEP		 protein:decreased expression:glomerulus
CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:kidney		 CTD PMID:21051829, PMID:19506087, PMID:17977875 RGD:2312464, RGD:2290351 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384 		JBrowse link
G Tjp2 tight junction protein 2 IEP protein:decreased expression:brain RGD PMID:17234953 RGD:1600163 NCBI chr 1:241,945,816...242,084,044
Ensembl chr 1:241,945,841...242,083,484 		JBrowse link
G Tlr4 toll-like receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27292124 PMID:32147540 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052 		JBrowse link
G Tnf tumor necrosis factor treatment IAGP
ISO
IMP		 CTD Direct Evidence: marker/mechanism CTD PMID:18605955 PMID:27292124 PMID:27659729 PMID:27847271 PMID:32147540, PMID:9590569, PMID:16415373 RGD:1357163, RGD:1580207 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B severity ISO protein:increased expression:serum RGD PMID:22050177 RGD:7205512 NCBI chr 7:93,798,580...93,826,586
Ensembl chr 7:93,798,545...93,826,665 		JBrowse link
G Tp53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22228705 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449 		JBrowse link
G Tpm1 tropomyosin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22228705 NCBI chr 8:72,814,737...72,841,496
Ensembl chr 8:72,814,740...72,842,228 		JBrowse link
G Trh thyrotropin releasing hormone IDA
ISO		 protein:decreased expression:diencephalon
CTD Direct Evidence: marker/mechanism		 CTD PMID:6350720, PMID:17227965 RGD:1600406 NCBI chr 4:124,110,716...124,113,242
Ensembl chr 4:124,110,716...124,113,242 		JBrowse link
G Trhr thyrotropin releasing hormone receptor IDA RGD PMID:7554113 RGD:1580745 NCBI chr 7:83,113,641...83,153,520
Ensembl chr 7:83,113,672...83,153,519 		JBrowse link
G Trpc3 transient receptor potential cation channel, subfamily C, member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17351372 NCBI chr 2:123,329,954...123,467,574
Ensembl chr 2:123,329,875...123,407,496 		JBrowse link
G Trpc5 transient receptor potential cation channel, subfamily C, member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17351372 NCBI chr  X:115,624,670...115,908,248
Ensembl chr  X:115,627,653...115,908,693 		JBrowse link
G Ucn urocortin ISO associated with Pregnancy Complications;protein:increased expression:plasma
CTD Direct Evidence: therapeutic		 CTD PMID:20237592, PMID:16915033 RGD:1642775 NCBI chr 6:26,602,144...26,602,974
Ensembl chr 6:26,602,144...26,602,974 		JBrowse link
G Ucn2 urocortin 2 ISO human protein in rat model RGD PMID:19204182 RGD:5508437 NCBI chr 8:117,727,216...117,728,765
Ensembl chr 8:117,727,877...117,728,764 		JBrowse link
G Ucp1 uncoupling protein 1 ISO DNA:polymorphism: :-3826A>G (human) RGD PMID:17635070 RGD:2313626 NCBI chr19:24,456,976...24,464,808
Ensembl chr19:24,456,976...24,464,807 		JBrowse link
G Ucp2 uncoupling protein 2 treatment ISO
IDA		 CTD Direct Evidence: marker/mechanism CTD PMID:16685210, PMID:15106800, PMID:20404217 RGD:1580794, RGD:7175297 NCBI chr 1:165,506,375...165,512,744
Ensembl chr 1:165,506,361...165,512,744 		JBrowse link
G Ucp3 uncoupling protein 3 IEP RGD PMID:10994754 RGD:1580795 NCBI chr 1:165,482,912...165,495,895
Ensembl chr 1:165,482,155...165,496,206 		JBrowse link
G Umod uromodulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:22228705 NCBI chr 1:189,186,027...189,199,939
Ensembl chr 1:189,186,026...189,199,376 		JBrowse link
G Uts2 urotensin 2 ISO
IDA		 protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism		 CTD PMID:16160878, PMID:15201550, PMID:14621188 RGD:1580808, RGD:1580812 NCBI chr 5:168,078,748...168,084,133
Ensembl chr 5:168,078,748...168,084,145 		JBrowse link
G Uts2r urotensin 2 receptor IDA RGD PMID:14621188 RGD:1580812 NCBI chr10:110,364,291...110,365,451
Ensembl chr10:110,364,291...110,365,451 		JBrowse link
G Vav3 vav guanine nucleotide exchange factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21115475 NCBI chr 2:212,247,061...212,585,818
Ensembl chr 2:212,247,451...212,585,818 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 disease_progression IEP
IAGP
ISO		 mRNA:increased expression:multiple organs
associated with SHRSP;mRNA,protein:increased expression:kidney, membrane fraction (rat)
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Type1; protein:increased expression:serum:		 CTD PMID:11834524 PMID:19018797, PMID:19080338, PMID:17938382, PMID:20569722 RGD:2313107, RGD:1643008, RGD:7241235 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619 		JBrowse link
G Vdr vitamin D receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:11335187 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166 		JBrowse link
G Vegfa vascular endothelial growth factor A treatment ISO associated with Prostatic Neoplasms RGD PMID:16164572, PMID:20630084 RGD:1580573, RGD:8552374 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681 		JBrowse link
G Vhl von Hippel-Lindau tumor suppressor ISO RGD PMID:12500216 RGD:1580371 NCBI chr 4:145,580,869...145,587,835
Ensembl chr 4:145,580,799...145,587,845 		JBrowse link
G Vwf von Willebrand factor treatment ISO
IEP		 CTD Direct Evidence: marker/mechanism
associated with Experimental Diabetes Mellitus		 CTD PMID:12149661 PMID:12425201 PMID:22352330, PMID:14737039 RGD:1601646 NCBI chr 4:158,085,059...158,219,525
Ensembl chr 4:158,088,505...158,219,523 		JBrowse link
G Wnk1 WNK lysine deficient protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22949526, PMID:16301342 RGD:1580829 NCBI chr 4:152,452,211...152,578,469
Ensembl chr 4:152,452,848...152,578,446 		JBrowse link
G Wnk4 WNK lysine deficient protein kinase 4 no_association IAGP
ISO		 CTD Direct Evidence: marker/mechanism CTD PMID:22949526, PMID:12642508, PMID:15110905 RGD:629611, RGD:1580830 NCBI chr10:89,181,139...89,198,213
Ensembl chr10:89,181,165...89,198,213 		JBrowse link
G Xdh xanthine dehydrogenase treatment IDA
IEP
ISO		 DNA:SNPs:exon, intron:47686C>T, 69901A>C, 67873A>C (p.N1109T) (human) RGD PMID:23746952, PMID:12826072, PMID:18712049, PMID:18728266 RGD:7247630, RGD:13210518, RGD:7247654, RGD:7247653 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494 		JBrowse link
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta treatment IEP RGD PMID:22984478 RGD:9587480 NCBI chr 7:75,573,553...75,598,295
Ensembl chr 7:75,574,967...75,597,276 		JBrowse link
angle-closure glaucoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E susceptibility ISO DNA:polymorphism:exon: RGD PMID:17706090 RGD:7771556 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057 		JBrowse link
G Cat catalase severity ISO DNA:SNP:promoter:g.4760C>T(rs1001179)(human) RGD PMID:23961996 RGD:9068947 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058 		JBrowse link
G Chat choline O-acetyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27064256 NCBI chr16:8,576,858...8,686,131
Ensembl chr16:8,577,840...8,686,131 		JBrowse link
G Col11a1 collagen type XI alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:22922875 PMID:27064256 NCBI chr 2:216,863,423...217,056,523
Ensembl chr 2:216,863,428...217,056,523 		JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain ISO ClinVar Annotator: match by term: GLAUCOMA, PRIMARY CLOSED-ANGLE ClinVar PMID:19390655 PMID:21862674 PMID:23667181 PMID:25741868 PMID:28041643 PMID:28492532 PMID:29977801 PMID:30007336 NCBI chr20:12,225,202...12,332,858
Ensembl chr20:12,225,202...12,332,858 		JBrowse link
G Edn1 endothelin 1 ISO protein:increased expression:plasma (human) RGD PMID:21946544 RGD:8661736 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324 		JBrowse link
G Epdr1 ependymin related 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27064256 NCBI chr17:47,397,558...47,422,183
Ensembl chr17:47,397,558...47,422,182 		JBrowse link
G Fermt2 FERM domain containing kindlin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27064256 NCBI chr15:19,807,806...19,876,557
Ensembl chr15:19,807,808...19,876,408 		JBrowse link
G Glis3 GLIS family zinc finger 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27064256 NCBI chr 1:246,380,816...246,564,385
Ensembl chr 1:246,380,889...246,785,360 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 susceptibility ISO DNA:deletion, haplotype:cds (human) RGD PMID:18334963 RGD:7488955 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306 		JBrowse link
G Hgf hepatocyte growth factor susceptibility ISO DNA:SNPs,haplotype::rs5745718,rs1742817(human) RGD PMID:23585864 RGD:8548548 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362 		JBrowse link
G Loxl1 lysyl oxidase-like 1 no_association ISO DNA:SNPs: :rs1048661, rs2165241, rs3825942 (human) RGD PMID:18223248 RGD:7394723 NCBI chr 8:63,067,757...63,092,124
Ensembl chr 8:63,067,300...63,092,009 		JBrowse link
G Mmp9 matrix metallopeptidase 9 no_association ISO DNA:SNP: :rs2664538 (human)
DNA:SNP:promoter:-1562C>T (human)
DNA:SNP: :c.836A>G (rs17576) (human)
DNA:SNPs: :rs17576, rs3918249 (human)		 RGD PMID:17110919, PMID:23441116, PMID:23441116, PMID:21655354 RGD:8547816, RGD:8549724, RGD:8549724, RGD:8547830 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase susceptibility ISO DNA:SNPs: :677C>T,1298A>C(human) RGD PMID:19936026 RGD:7387250 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910 		JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming ISO associated with Cataract;protein:decreased expression:tear RGD PMID:21139981 RGD:7364742 NCBI chr 1:214,725,482...214,756,653 JBrowse link
G Nos3 nitric oxide synthase 3 susceptibility ISO DNA:duplication:intron:IVS4?-?+27 (human)
DNA:snps:introns:g.IVS5+1182G>A, g.IVS25+11C>A (rs3793342, rs7830) (human)		 RGD PMID:20069064, PMID:23422825 RGD:7771573, RGD:7775046 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410 		JBrowse link
G Plekha7 pleckstrin homology domain containing A7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22922875 PMID:27064256 NCBI chr 1:185,427,600...185,493,985
Ensembl chr 1:185,356,975...185,538,694 		JBrowse link
G Prss56 serine protease 56 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21532570 NCBI chr 9:94,278,981...94,284,111
Ensembl chr 9:94,279,155...94,283,919 		JBrowse link
G Sh3pxd2b SH3 and PX domains 2B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28719234 NCBI chr10:17,209,152...17,296,449
Ensembl chr10:17,209,212...17,291,876 		JBrowse link
G Slc19a1 solute carrier family 19 member 1 ISO ClinVar Annotator: match by term: GLAUCOMA, PRIMARY CLOSED-ANGLE ClinVar PMID:19390655 PMID:21862674 PMID:23667181 PMID:25741868 PMID:28041643 PMID:28492532 PMID:29977801 NCBI chr20:12,334,675...12,354,517
Ensembl chr20:12,334,676...12,352,377 		JBrowse link
G Tfap2b transcription factor AP-2 beta ISS MouseDO NCBI chr 9:25,410,669...25,440,568
Ensembl chr 9:25,410,669...25,440,411 		JBrowse link
anterior segment dysgenesis 3 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxc1 forkhead box C1 ISO ClinVar Annotator: match by term: Anterior segment dysgenesis 3
ClinVar Annotator: match by term: Iridogoniodysgenesis type1
ClinVar Annotator: match by OMIM:601631		 OMIM
ClinVar		 PMID:9620769 PMID:9792859 PMID:11007653 PMID:11170889 PMID:12036988 PMID:19668217 PMID:19793056 PMID:25741868 PMID:28492532 PMID:32832252 NCBI chr17:33,947,501...33,951,484
Ensembl chr17:33,947,506...33,951,484 		JBrowse link
anterior segment dysgenesis 4 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pitx2 paired-like homeodomain 2 ISO ClinVar Annotator: match by term: Anterior segment dysgenesis 4
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: ANTERIOR SEGMENT DYSGENESIS 4
ClinVar Annotator: match by term: Iridogoniodysgenesis, dominant type
ClinVar Annotator: match by OMIM:137600		 OMIM
ClinVar
CTD		 PMID:7581385 PMID:8942889 PMID:9437321 PMID:9618168 PMID:10502778 PMID:25741868 PMID:28492532 PMID:32499604 NCBI chr 2:233,602,732...233,621,059
Ensembl chr 2:233,602,732...233,621,129 		JBrowse link
buphthalmos term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 susceptibility ISO ClinVar Annotator: match by term: Glaucoma 3, primary congenital, A
ClinVar Annotator: match by term: Glaucoma, congenital
ClinVar Annotator: match by term: Glaucoma, primary open angle, juvenile-onset
ClinVar Annotator: match by term: Congenital glaucoma
ClinVar Annotator: match by OMIM:231300
DNA:missense mutation:cds:p.A388T (human)
DNA:missense mutation, deletion:exon:p.R390H, g.4633delC (human)
DNA:duplication:exon:g.1546-1555dupTCATGCCACC (human)
DNA:missense mutations:exons:p.G61E, p.R368H, p.D374N (human)
DNA:missense mutations:exons:p.G61E, p.R469W, p.R523K (human)
DNA:deletion, snp:exons:g.4339delG, p.G61E (human)
DNA:snp:cds:p.E387K (human)
DNA:polymorphisms:multiple (human)		 OMIM
ClinVar		 PMID:9097971 PMID:9463332 PMID:9497261 PMID:10227395 PMID:10426814 PMID:10655546 PMID:10739169 PMID:10910054 PMID:11403040 PMID:11527932 PMID:11558822 PMID:11774072 PMID:11854439 PMID:11980847 PMID:12036985 PMID:12372064 PMID:14507861 PMID:15037581 PMID:15255109 PMID:15342693 PMID:16384942 PMID:16688110 PMID:16735991 PMID:16735994 PMID:16862072 PMID:17164573 PMID:17363580 PMID:17563717 PMID:17591938 PMID:17718864 PMID:18227148 PMID:18414103 PMID:18470941 PMID:18537981 PMID:18622259 PMID:18852424 PMID:19204079 PMID:19234632 PMID:19236111 PMID:19247456 PMID:19536304 PMID:19597567 PMID:19643970 PMID:19744731 PMID:19793111 PMID:19807744 PMID:20151268 PMID:20198978 PMID:20664688 PMID:21081970 PMID:21168818 PMID:21600657 PMID:21815720 PMID:21850185 PMID:21854771 PMID:22004014 PMID:22128238 PMID:22942166 PMID:23028769 PMID:23218183 PMID:23218701 PMID:23922489 PMID:24033266 PMID:24123366 PMID:24281366 PMID:24940937 PMID:25091052 PMID:25109919 PMID:25333069 PMID:25527694 PMID:25646030 PMID:25741868 PMID:25950505 PMID:25978063 PMID:26550974 PMID:27060699 PMID:27243976 PMID:27272408 PMID:27408750 PMID:27508083 PMID:27535533 PMID:27777502 PMID:27820421 PMID:28192799 PMID:28384041 PMID:28448622 PMID:28492532 PMID:28620713 PMID:29556725 PMID:30653986 PMID:30788381 PMID:32499604 PMID:32832252 PMID:32860008 PMID:94927261, PMID:16490498, PMID:19247456, PMID:12567107, PMID:19597567, PMID:19593207, PMID:20664688, PMID:10227395, PMID:23922489, PMID:12624268 RGD:7800719, RGD:7800711, RGD:7800707, RGD:7800689, RGD:7800688, RGD:7800680, RGD:7800670, RGD:7800657, RGD:734869 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722 		JBrowse link
G Foxc1 forkhead box C1 ISS OMIM:231300 MouseDO NCBI chr17:33,947,501...33,951,484
Ensembl chr17:33,947,506...33,951,484 		JBrowse link
G Ltbp2 latent transforming growth factor beta binding protein 2 ISO ClinVar Annotator: match by term: Glaucoma, congenital ClinVar PMID:19656777 NCBI chr 6:108,500,114...108,596,653
Ensembl chr 6:108,500,112...108,596,569 		JBrowse link
G Myoc myocilin ISO ClinVar Annotator: match by term: Glaucoma 3, primary congenital, a, digenic ClinVar PMID:12447164 PMID:15025728 PMID:15723004 PMID:15733270 PMID:16288197 PMID:17563717 PMID:22194650 PMID:22736945 NCBI chr13:80,517,531...80,527,928
Ensembl chr13:80,517,536...80,527,928 		JBrowse link
G Rmdn2 regulator of microtubule dynamics 2 ISO ClinVar Annotator: match by term: Glaucoma 3, primary congenital, A ClinVar NCBI chr 6:2,215,062...2,292,288
Ensembl chr 6:2,216,623...2,280,777 		JBrowse link
G Tyr tyrosinase ISS OMIM:231300 MouseDO NCBI chr 1:151,012,598...151,106,802
Ensembl chr 1:151,012,598...151,106,802 		JBrowse link
Charcot-Marie-Tooth disease type 4B2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sbf2 SET binding factor 2 ISO ClinVar Annotator: match by term: Charcot-Marie-Tooth disease, type 4B2
ClinVar Annotator: match by term: Charcot-Marie-Tooth disease type 4B2 with early-onset glaucoma
ClinVar Annotator: match by OMIM:604563
ClinVar Annotator: match by null		 OMIM
ClinVar		 PMID:9521281 PMID:10932274 PMID:12554688 PMID:12687498 PMID:15304601 PMID:15477569 PMID:25025039 PMID:25741868 PMID:26392352 PMID:26467025 PMID:27582484 PMID:28492532 NCBI chr 1:174,948,361...175,420,161
Ensembl chr 1:174,948,913...175,420,160 		JBrowse link
Diastolic Hypertension, Resistance to term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnip1 potassium voltage-gated channel interacting protein 1 ISO ClinVar Annotator: match by null ClinVar PMID:15057310 PMID:16155733 NCBI chr10:18,558,128...18,942,677
Ensembl chr10:18,558,128...18,942,540 		JBrowse link
G Kcnmb1 potassium calcium-activated channel subfamily M regulatory beta subunit 1 ISO ClinVar Annotator: match by OMIM:608622 OMIM
ClinVar		 PMID:15057310 PMID:16155733 NCBI chr10:18,910,586...18,922,856
Ensembl chr10:18,906,010...18,919,639 		JBrowse link
Dursun Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6pc3 glucose 6 phosphatase catalytic subunit 3 ISO ClinVar Annotator: match by term: Dursun syndrome ClinVar PMID:19011569 PMID:20799326 PMID:25741868 NCBI chr10:90,134,193...90,138,425
Ensembl chr10:90,134,193...90,138,425 		JBrowse link
eclampsia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il6 interleukin 6 treatment IDA RGD PMID:27106269 RGD:11062145 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807 		JBrowse link
essential hypertension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsm3 acyl-CoA synthetase medium-chain family member 3 no_association ISO RGD PMID:11592044 RGD:1579978 NCBI chr 1:189,514,504...189,541,233
Ensembl chr 1:189,514,553...189,541,224 		JBrowse link
G Add1 adducin 1 ISO ClinVar Annotator: match by term: Hypertension, salt-sensitive essential, susceptibility to OMIM
ClinVar		 PMID:9149697 PMID:9607177 PMID:10024330 PMID:21692745 PMID:22992668 NCBI chr14:81,367,466...81,426,610
Ensembl chr14:81,367,468...81,426,496 		JBrowse link
G Agt angiotensinogen ISO ClinVar Annotator: match by term: Hypertension, essential, susceptibility to OMIM
ClinVar		 PMID:7649545 PMID:7883995 PMID:8348146 PMID:8513325 PMID:8518804 PMID:9120024 PMID:9259580 PMID:9421481 PMID:9831339 PMID:9894356 PMID:13937884 PMID:15077204 PMID:16059745 PMID:17047091 PMID:20978123 PMID:25741868 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a treatment ISO ClinVar Annotator: match by term: Hypertension, essential, susceptibility to OMIM
ClinVar		 PMID:8021009 PMID:9084931 PMID:15042429 PMID:17668390, PMID:18604484 RGD:10047396 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077 		JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 ISO OMIM NCBI chr13:82,737,161...82,757,681
Ensembl chr13:82,737,159...82,758,004 		JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 susceptibility ISO DNA:polymorphism:exon:p.A724A (c.2171G>A)(human) RGD PMID:20687374 RGD:13507310 NCBI chr12:39,553,903...39,603,326
Ensembl chr12:39,553,903...39,603,326 		JBrowse link
G Atp5pf ATP synthase peripheral stalk subunit F6 ISO protein:increased expression:plasma (human) RGD PMID:14654753 RGD:13800915 NCBI chr11:24,286,806...24,294,419
Ensembl chr11:24,286,787...24,294,179 		JBrowse link
G Cat catalase ISO RGD PMID:15735318 RGD:1581147 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 ISO ClinVar Annotator: match by term: Hypertension, salt-sensitive essential, susceptibility to OMIM
ClinVar		 PMID:11279519 PMID:11740341 PMID:12065767 PMID:12754175 PMID:15492926 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399 		JBrowse link
G Ece1 endothelin converting enzyme 1 ISO OMIM NCBI chr 5:156,215,469...156,318,652
Ensembl chr 5:156,215,417...156,318,671 		JBrowse link
G Eln elastin ISS OMIM:145500 | OMIM:603918 | OMIM:604329 | OMIM:607329 | OMIM:608742 | OMIM:610261 | OMIM:610262 | OMIM:610948 | OMIM:611014 MouseDO NCBI chr12:24,978,478...25,021,864
Ensembl chr12:24,978,483...25,021,863 		JBrowse link
G Gata5 GATA binding protein 5 ISS OMIM:145500 | OMIM:603918 | OMIM:604329 | OMIM:607329 | OMIM:608742 | OMIM:610261 | OMIM:610262 | OMIM:610948 | OMIM:611014 MouseDO NCBI chr 3:175,701,278...175,709,465
Ensembl chr 3:175,701,280...175,709,465 		JBrowse link
G Gnb3 G protein subunit beta 3 ISO OMIM NCBI chr 4:157,352,558...157,359,237
Ensembl chr 4:157,352,372...157,358,262 		JBrowse link
G Grk4 G protein-coupled receptor kinase 4 susceptibility ISO DNA:SNP,haplotypes:cds: RGD PMID:15097232, PMID:15097232 RGD:1598505, RGD:1598505 NCBI chr14:81,261,708...81,339,516
Ensembl chr14:81,265,672...81,339,526 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 ISO protein:increased expression:urine: RGD PMID:22923545 RGD:7245500 NCBI chr10:31,813,819...31,860,934
Ensembl chr10:31,813,814...31,848,379 		JBrowse link
G Lcn2 lipocalin 2 ISO protein:increased expression:urine: RGD PMID:22923545 RGD:7245500 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546 		JBrowse link
G Nos3 nitric oxide synthase 3 ISO DNA:repeats:intron:IVS13+?-?dupCA (human)
ClinVar Annotator: match by term: Essential hypertension
DNA:snp:cds:p.E298D (human)		 ClinVar
OMIM		 PMID:25741868, PMID:9084930, PMID:11394896 RGD:1580277, RGD:1580280 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410 		JBrowse link
G Nppb natriuretic peptide B ISO protein:increased expression:plasma: RGD PMID:9350073 RGD:7246914 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531 		JBrowse link
G Npr2 natriuretic peptide receptor 2 ISO DNA:repeat:intron:IVS2+150(GT)10-11 (human) RGD PMID:10082481 RGD:1580772 NCBI chr 5:59,128,186...59,147,321
Ensembl chr 5:59,128,315...59,147,255 		JBrowse link
G Ptgis prostaglandin I2 synthase ISO ClinVar Annotator: match by OMIM:145500 OMIM
ClinVar		 PMID:12372404 NCBI chr 3:163,950,746...163,986,129 JBrowse link
G Rarres2 retinoic acid receptor responder 2 ISO protein:increased expression:serum: RGD PMID:24047472 RGD:15036820 NCBI chr 4:78,205,809...78,208,956
Ensembl chr 4:78,205,812...78,208,767 		JBrowse link
G Rgs5 regulator of G-protein signaling 5 ISO OMIM NCBI chr13:87,966,820...88,002,831
Ensembl chr13:87,966,758...88,003,035 		JBrowse link
G Rnls renalase, FAD-dependent amine oxidase ISO DNA:SNPs: :rs2576178, rs2296545,rs2114406 (human) RGD PMID:17216203 RGD:7327177 NCBI chr 1:251,828,285...252,101,963
Ensembl chr 1:251,828,290...252,100,759 		JBrowse link
G Slc12a3 solute carrier family 12 member 3 severity ISO DNA:missense mutation:cds:p.R904Q (human)
DNA:snp:intron:g.1784C>T (human)		 RGD PMID:15480096, PMID:15824464 RGD:1580589, RGD:1580586 NCBI chr19:11,106,033...11,144,674
Ensembl chr19:11,106,033...11,144,641 		JBrowse link
G Umod uromodulin ISO ClinVar Annotator: match by term: Essential hypertension ClinVar NCBI chr 1:189,186,027...189,199,939
Ensembl chr 1:189,186,026...189,199,376 		JBrowse link
exfoliation syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agpat1 1-acylglycerol-3-phosphate O-acyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28553957 NCBI chr20:4,369,399...4,378,272
Ensembl chr20:4,369,178...4,378,269 		JBrowse link
G Apoe apolipoprotein E susceptibility ISO DNA:polymorphism:exon: RGD PMID:15939044 RGD:7771555 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057 		JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A ISO CTD Direct Evidence: marker/mechanism CTD PMID:25706626 NCBI chr19:25,453,236...25,749,550
Ensembl chr19:25,526,751...25,749,550 		JBrowse link
G Cav1 caveolin 1 no_association ISO DNA:SNP:promoter:rs4236601 (human) RGD PMID:20835238 RGD:8661783 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200 		JBrowse link
G Clu clusterin no_association ISO DNA:SNPs, haplotype: :multiple
DNA:SNP:intron:rs2279590 (human)		 RGD PMID:18806885, PMID:25057782, PMID:19182256, PMID:19182256, PMID:16639006 RGD:8699505, RGD:9068391, RGD:8887372, RGD:8887372, RGD:8699516 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857 		JBrowse link
G Edn1 endothelin 1 ISO associated with Cataract;protein:increased expression:aqueous humor (human) RGD PMID:15031170 RGD:8661674 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324 		JBrowse link
G Eln elastin ISO RGD PMID:7777294 RGD:9585736 NCBI chr12:24,978,478...25,021,864
Ensembl chr12:24,978,483...25,021,863 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 susceptibility
no_association		 ISO DNA:deletion, haplotype:cds (human)
DNA:deletion:cds (human)		 RGD PMID:18334963, PMID:16020292 RGD:7488955, RGD:7495792 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 susceptibility
no_association		 ISO DNA:deletion:cds (human)
mRNA:decreased expression:ciliary processes, iris (human)		 RGD PMID:21151336, PMID:18055805, PMID:16020292 RGD:7794822, RGD:7794853, RGD:7495792 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526 		JBrowse link
G Loxl1 lysyl oxidase-like 1 susceptibility
no_association		 ISO DNA:SNP: :p.R141L (rs1048661) (human)
ClinVar Annotator: match by term: Exfoliation syndrome, susceptibility to
CTD Direct Evidence: marker/mechanism
DNA:CNVs
DNA:SNPs:exon:p.R141L, p.G153D (human)
DNA:SNP, haplotypes:promoter:multiple
DNA:SNP:exon:rs1048661, rs3825942 (human)
DNA:SNP, haplotypes: :rs1048661, rs3825942 (human)
DNA:SNP: :multiple		 ClinVar
OMIM
CTD		 PMID:17690259 PMID:18037624 PMID:19343041 PMID:25706626 PMID:28553957, PMID:23378724, PMID:19029039, PMID:23288989, PMID:21320968, PMID:21212179, PMID:21740868, PMID:22605916, PMID:19503743, PMID:19373106 RGD:7387325, RGD:7394726, RGD:7387333, RGD:7387332, RGD:7387331, RGD:7387329, RGD:7387328, RGD:7387327, RGD:7387326 NCBI chr 8:63,067,757...63,092,124
Ensembl chr 8:63,067,300...63,092,009 		JBrowse link
G Ltbp2 latent transforming growth factor beta binding protein 2 ISO ClinVar Annotator: match by term: Exfoliation Syndrome
ClinVar Annotator: match by term: Pseudoexfoliation glaucoma		 ClinVar PMID:23401661 PMID:28492532 NCBI chr 6:108,500,114...108,596,653
Ensembl chr 6:108,500,112...108,596,569 		JBrowse link
G Lyst lysosomal trafficking regulator ISS OMIM:177650 MouseDO NCBI chr17:90,323,055...90,522,091 JBrowse link
G Mmp1 matrix metallopeptidase 1 no_association ISO DNA:insertion:promoter:g.-1607insG rs1799750 (human) RGD PMID:20808730 RGD:8549725 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591 		JBrowse link
G Mmp9 matrix metallopeptidase 9 no_association ISO DNA:insertion: :p.Q279R (rs17576) (human) RGD PMID:20808730 RGD:8549725 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520 		JBrowse link
G Optn optineurin no_association ISO DNA:polymorphism: :p.M98K (human) RGD PMID:16020311 RGD:6480509 NCBI chr17:77,167,700...77,218,374
Ensembl chr17:77,167,740...77,218,389 		JBrowse link
G Pomp proteasome maturation protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28553957 NCBI chr12:8,746,948...8,759,433
Ensembl chr12:8,746,855...8,759,599 		JBrowse link
G Pon1 paraoxonase 1 ISO protein:decreased expression:serum (human) RGD PMID:19628957 RGD:8547685 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372 		JBrowse link
G Rbms3 RNA binding motif, single stranded interacting protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28553957 NCBI chr 8:124,833,804...125,645,895
Ensembl chr 8:124,661,839...125,645,898 		JBrowse link
G Sod2 superoxide dismutase 2 ISO associated with cataract;mRNA:increased expression:lens epithelium:
associated with glaucoma,primary open angle; mRNA:increased expression: ciliary body, iris:		 RGD PMID:23805041, PMID:18055805 RGD:8158048, RGD:7794853 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587 		JBrowse link
G Tlcd5 TLC domain containing 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28553957 NCBI chr 8:47,399,122...47,404,018
Ensembl chr 8:47,396,741...47,404,010 		JBrowse link
G Tlr4 toll-like receptor 4 susceptibility ISO DNA:haplotype:: RGD PMID:22831837 RGD:7794768 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052 		JBrowse link
glaucoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace2 angiotensin I converting enzyme 2 treatment IDA RGD PMID:23702784 RGD:9685447 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016 		JBrowse link
G Anxa3 annexin A3 IEP mRNA:increased expression:retina RGD PMID:18055803 RGD:2289160 NCBI chr14:14,371,921...14,426,503
Ensembl chr14:14,364,008...14,426,437 		JBrowse link
G Apoa4 apolipoprotein A4 ISO Primary Congenital Glaucoma; protein:increased expression:aqueous humor (human) RGD PMID:21078314 RGD:5685641 NCBI chr 8:50,536,983...50,539,371
Ensembl chr 8:50,537,009...50,539,376 		JBrowse link
G Apoe apolipoprotein E ISO GAD PMID:15118671 RGD:1331525 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057 		JBrowse link
G Atf2 activating transcription factor 2 IEP RGD PMID:17586494 RGD:10047416 NCBI chr 3:60,721,137...60,795,951
Ensembl chr 3:60,721,135...60,795,951 		JBrowse link
G Bad BCL2-associated agonist of cell death IEP protein:decreased serine phosphorylation:retina RGD PMID:16103353 RGD:2292690 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator IEP mRNA:increased expression:optic nerve, retina RGD PMID:24357921 RGD:10054098 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207 		JBrowse link
G Bcl2 BCL2, apoptosis regulator IEP mRNA:decreased expression:optic nerve, retina RGD PMID:24357921 RGD:10054098 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374 		JBrowse link
G Bdnf brain-derived neurotrophic factor treatment ISO
IDA
IEP		 protein:decreased expression:eye: RGD PMID:19422885, PMID:21498611, PMID:10711692 RGD:8655601, RGD:8655886, RGD:8655608 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210 		JBrowse link
G Becn1 beclin 1 IEP protein:increased expression:eye RGD PMID:22476098 RGD:6483048 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297 		JBrowse link
G Bex3 brain expressed X-linked 3 IEP mRNA:decreased expression:retina RGD PMID:19682984 RGD:9743977 NCBI chr  X:106,823,442...106,825,016
Ensembl chr  X:106,823,491...106,825,014 		JBrowse link
G Ccnd2 cyclin D2 IEP mRNA:increased expression:retina RGD PMID:18055803 RGD:2289160 NCBI chr 4:159,674,885...159,697,207
Ensembl chr 4:159,674,885...159,697,207 		JBrowse link
G Ccr5 C-C motif chemokine receptor 5 ISO RGD PMID:16159632 RGD:8549757 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B IEP mRNA, protein:decreased expression:retina, Muller cell RGD PMID:16707124 RGD:2293623 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:21532571 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175 		JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B ISO CTD Direct Evidence: marker/mechanism CTD PMID:21532571 NCBI chr 5:107,834,353...107,857,428
Ensembl chr 5:107,845,951...107,858,104 		JBrowse link
G Cfh complement factor H ISO protein:decreased expression:retina: RGD PMID:20484586 RGD:7364950 NCBI chr13:56,979,155...57,080,540
Ensembl chr13:56,978,607...57,080,622 		JBrowse link
G Cntf ciliary neurotrophic factor IDA
ISO		 RGD PMID:14725620, PMID:19060281 RGD:1626115, RGD:8655853 NCBI chr 1:229,599,009...229,601,032
Ensembl chr 1:229,599,009...229,601,032 		JBrowse link
G Crebbp CREB binding protein ISO ClinVar Annotator: match by term: Glaucoma ClinVar PMID:25741868 NCBI chr10:11,590,994...11,721,039
Ensembl chr10:11,595,044...11,721,039 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 ISO RGD PMID:24989686 RGD:9384823 NCBI chr 8:128,740,756...128,754,514
Ensembl chr 8:128,740,756...128,754,514 		JBrowse link
G Eef2 eukaryotic translation elongation factor 2 ISO associated with Exfoliation Syndrome; RGD PMID:20107165 RGD:10401222 NCBI chr 7:11,401,501...11,406,771
Ensembl chr 7:11,401,501...11,406,771 		JBrowse link
G Epo erythropoietin ISO
IEP		 protein:increased expression:retina: RGD PMID:19741249, PMID:17554621, PMID:17554621 RGD:10401071, RGD:11041649, RGD:11041649 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266 		JBrowse link
G Epor erythropoietin receptor IEP protein:increased expression:retina: RGD PMID:17554621 RGD:11041649 NCBI chr 8:22,969,737...22,974,468
Ensembl chr 8:22,969,745...22,974,321 		JBrowse link
G Fas Fas cell surface death receptor ISO protein:increased expression:optic nerve head, axon (human) RGD PMID:19043361 RGD:8662440 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790 		JBrowse link
G Foxc1 forkhead box C1 ISO associated with Axenfeld-Rieger Syndrome;DNA:mutation:cds:p.Q120X(human) RGD PMID:18498376 RGD:12904045 NCBI chr17:33,947,501...33,951,484
Ensembl chr17:33,947,506...33,951,484 		JBrowse link
G Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 ISS MouseDO NCBI chr 3:101,051,960...101,152,119
Ensembl chr 3:101,051,955...101,152,119 		JBrowse link
G Lingo1 leucine rich repeat and Ig domain containing 1 treatment ISO RGD PMID:19422885 RGD:8655601 NCBI chr 8:61,272,125...61,455,480
Ensembl chr 8:61,274,017...61,290,240 		JBrowse link
G Ltbp2 latent transforming growth factor beta binding protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19361779 PMID:27149523 NCBI chr 6:108,500,114...108,596,653
Ensembl chr 6:108,500,112...108,596,569 		JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha IEP protein:increased expression:optic nerve RGD PMID:24136224 RGD:13782046 NCBI chr 3:150,801,289...150,802,935
Ensembl chr 3:150,801,289...150,802,935 		JBrowse link
G Mas1 MAS1 proto-oncogene, G protein-coupled receptor treatment IMP RGD PMID:23702784 RGD:9685447 NCBI chr 1:48,076,761...48,108,218
Ensembl chr 1:48,077,033...48,108,216 		JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO RGD PMID:16185954 RGD:8547817 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520 		JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming ISO protein:increased expression:conjunctival epithelial cell RGD PMID:16809382 RGD:7364743 NCBI chr 1:214,725,482...214,756,653 JBrowse link
G Mylk myosin light chain kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20375339 NCBI chr11:69,013,060...69,260,039
Ensembl chr11:69,013,050...69,223,158 		JBrowse link
G Myoc myocilin TAS
ISO		 ClinVar Annotator: match by term: Glaucoma
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD		 PMID:9535666 PMID:9772276 PMID:9804137 PMID:10196380 PMID:10330365 PMID:10545602 PMID:10798654 PMID:10980537 PMID:11004290 PMID:11133859 PMID:11152659 PMID:11281418 PMID:11298682 PMID:11803488 PMID:12189160 PMID:12356829 PMID:12442283 PMID:12872267 PMID:14688426 PMID:14764620 PMID:14767915 PMID:15790895 PMID:16148883 PMID:16466712 PMID:16636654 PMID:17438518 PMID:17893664 PMID:18776955 PMID:19145250 PMID:21552496 PMID:21850185 PMID:22736945 PMID:22933836 PMID:23029558 PMID:23922489 PMID:24033266 PMID:25741868 PMID:27485216 PMID:28492532 PMID:30389787 PMID:31959993, PMID:10833334 RGD:633384 NCBI chr13:80,517,531...80,527,928
Ensembl chr13:80,517,536...80,527,928 		JBrowse link
G Nefh neurofilament heavy IEP protein:decreased expression:optic nerve: RGD PMID:28498493 RGD:27226819 NCBI chr14:85,181,572...85,191,557
Ensembl chr14:85,181,572...85,191,557 		JBrowse link
G Ngf nerve growth factor IEP protein:decreased expression:cerebrospinal fluid RGD PMID:18938194 RGD:2303806 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453 		JBrowse link
G Ngfr nerve growth factor receptor IDA RGD PMID:20943663 RGD:5508695 NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061 		JBrowse link
G Nmnat3 nicotinamide nucleotide adenylyltransferase 3 treatment IDA RGD PMID:24136224 RGD:13782046 NCBI chr 8:106,317,038...106,429,535
Ensembl chr 8:106,317,124...106,429,522 		JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 IEP
IDA		 mRNA,protein:decreased expression:eye RGD PMID:18817846, PMID:20943663 RGD:5684379, RGD:5508695 NCBI chr 2:187,143,568...187,160,373
Ensembl chr 2:187,143,568...187,160,373 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 IDA
IEP		 protein:increased expression:eye: RGD PMID:20357199, PMID:10711692 RGD:5684908, RGD:8655608 NCBI chr17:5,934,651...6,245,778
Ensembl chr17:5,933,729...6,244,676 		JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase treatment ISO RGD PMID:18936150, PMID:20664796 RGD:7800698, RGD:7800720 NCBI chr11:74,717,600...74,793,902
Ensembl chr11:74,720,254...74,793,803 		JBrowse link
G Optn optineurin susceptibility ISO DNA:SNP:intron: RGD PMID:16148883 RGD:7771548 NCBI chr17:77,167,700...77,218,374
Ensembl chr17:77,167,740...77,218,389 		JBrowse link
G Pitx2 paired-like homeodomain 2 ISS MouseDO NCBI chr 2:233,602,732...233,621,059
Ensembl chr 2:233,602,732...233,621,129 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO protein:increased expression:microglia RGD PMID:11391707 RGD:5688244 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344 		JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 treatment ISO
IMP
IEP		 protein:increased phosphorylation:retina
protein:increased expression,increased phosphorylation:retina		 RGD PMID:30341011, PMID:30341011, PMID:30341011 RGD:39456090, RGD:39456090, RGD:39456090 NCBI chr12:40,895,515...40,955,999
Ensembl chr12:40,895,515...40,955,999 		JBrowse link
G RT1-Bb RT1 class II, locus Bb susceptibility ISO DNA:polymorphisms, haplotype:cds:HLA-DQB1*0302 (human) RGD PMID:10511023 RGD:7365116 NCBI chr20:4,043,726...4,049,367
Ensembl chr20:4,039,413...4,049,711 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 susceptibility ISO DNA:Haplotype: :HLA-DRB1*0407(human) RGD PMID:10511023 RGD:7365116 NCBI chr20:4,087,621...4,097,190
Ensembl chr20:4,087,618...4,097,190 		JBrowse link
G Serpine1 serpin family E member 1 ISO protein:increased expression:aqueous humor (human) RGD PMID:15710819 RGD:8547695 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482 		JBrowse link
G Sh3pxd2b SH3 and PX domains 2B ISS MouseDO NCBI chr10:17,209,152...17,296,449
Ensembl chr10:17,209,212...17,291,876 		JBrowse link
G Slc4a4 solute carrier family 4 member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18614622 NCBI chr14:20,476,258...20,817,042
Ensembl chr14:20,479,323...20,920,286 		JBrowse link
G Sncg synuclein, gamma ISO
IEP		 mRNA, protein:decreased expression:optic nerve RGD PMID:18728752, PMID:11933054 RGD:6218971, RGD:6480100 NCBI chr16:10,722,110...10,726,648
Ensembl chr16:10,722,106...10,726,707 		JBrowse link
G Sqstm1 sequestosome 1 IEP protein:increased expression:optic nerve RGD PMID:24136224 RGD:13782046 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294 		JBrowse link
G Tdrd7 tudor domain containing 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21436445 NCBI chr 5:61,557,909...61,631,719
Ensembl chr 5:61,564,864...61,631,710 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20375339 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030 		JBrowse link
G Tnf tumor necrosis factor IEP
ISO
IMP		 protein:increased expression:retina RGD PMID:20574020, PMID:17151265, PMID:22802951, PMID:20574020 RGD:7394760, RGD:7394785, RGD:7394770, RGD:7394760 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Txn1 thioredoxin 1 IEP protein:decreased expression:retinal ganglion cell RGD PMID:18701913 RGD:2306193 NCBI chr 5:75,049,735...75,057,731
Ensembl chr 5:75,049,747...75,057,752 		JBrowse link
G Txnip thioredoxin interacting protein IEP protein:increased expression:retinal ganglion cell RGD PMID:18701913