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ONTOLOGY REPORT - ANNOTATIONS


Term:otitis media
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Accession:DOID:10754 term browser browse the term
Definition:Inflammation of the MIDDLE EAR including the AUDITORY OSSICLES and the EUSTACHIAN TUBE.
Synonyms:exact_synonym: COME/ROM;   Middle Ear Inflammation;   OMS;   OTITIS MEDIA, CHRONIC/RECURRENT;   OTITIS MEDIA, SUSCEPTIBILITY TO
 narrow_synonym: Nonsyndromic otitis media
 primary_id: MESH:D010033
 alt_id: OMIM:166760;   RDO:0006074
 xref: NCI:C34885
For additional species annotation, visit the Alliance of Genome Resources.


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otitis media term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bpifa1 BPI fold containing family A member 1 JBrowse link NW_004955422 28,063,077 28,069,939 RGD:9068941
G Btc betacellulin JBrowse link NW_004955474 895,573 946,152 RGD:9068941
G C2 complement C2 JBrowse link NW_004955437 449,171 460,898 RGD:9068941
G C3 complement C3 JBrowse link NW_004955495 2,796,601 2,824,233 RGD:9068941
RGD:11554035
G Cat catalase JBrowse link NW_004955422 11,783,973 11,826,970 RGD:9068941
G Cby1 chibby family member 1, beta catenin antagonist JBrowse link NW_004955413 24,781,102 24,794,537 RGD:9068941
G Cfb complement factor B JBrowse link NW_004955437 461,235 466,908 RGD:9068941
G Ctsb cathepsin B JBrowse link NW_004955403 53,086,236 53,100,217 RGD:9068941
G Ctsk cathepsin K JBrowse link NW_004955588 149,036 158,093 RGD:9068941
G Cx3cr1 C-X3-C motif chemokine receptor 1 JBrowse link NW_004955427 24,691,206 24,705,599 RGD:9068941
G Cxcl8 C-X-C motif chemokine ligand 8 JBrowse link NW_004955474 247,326 250,355 RGD:11553900
RGD:9068941
G Cysltr2 cysteinyl leukotriene receptor 2 JBrowse link NW_004955431 2,203,342 2,282,635 RGD:11553910
RGD:9068941
G Dnah5 dynein axonemal heavy chain 5 JBrowse link NW_004955426 3,105,631 3,406,587 RGD:9068941
G Dusp1 dual specificity phosphatase 1 JBrowse link NW_004955408 25,481,294 25,484,381 RGD:9068941
G E2f4 E2F transcription factor 4 JBrowse link NW_004955484 9,421,396 9,427,826 RGD:9068941
G Eda ectodysplasin A JBrowse link NW_004955475 9,177,911 9,592,150 RGD:9068941
G Edar ectodysplasin A receptor JBrowse link NW_004955470 12,310,680 12,362,555 RGD:9068941
G Edaradd EDAR associated death domain JBrowse link NW_004955492 3,709,819 3,777,506 RGD:9068941
G Eya4 EYA transcriptional coactivator and phosphatase 4 JBrowse link NW_004955436 13,710,366 13,982,379 RGD:9068941
G Fbxo11 F-box protein 11 JBrowse link NW_004955441 14,471,283 14,495,508 RGD:9068941
G Fgfr1 fibroblast growth factor receptor 1 JBrowse link NW_004955463 14,013,247 14,064,354 RGD:9068941
G Icam1 intercellular adhesion molecule 1 JBrowse link NW_004955495 1,561,464 1,573,282 RGD:9068941
G Idua iduronidase alpha-L- JBrowse link NW_004955514 474,830 488,007 RGD:9068941
G Ifng interferon gamma JBrowse link NW_004955458 14,643,333 14,648,020 RGD:9068941
G Il10 interleukin 10 JBrowse link NW_004955406 42,307,789 42,312,255 RGD:9068941
G Il17a interleukin 17A JBrowse link NW_004955411 5,896,435 5,899,911 RGD:9068941
G Il1a interleukin 1 alpha JBrowse link NW_004955470 1,527,710 1,538,418 RGD:9068941
G Il1b interleukin 1 beta JBrowse link NW_004955470 1,486,936 1,491,888 RGD:9068941
RGD:11553900
G Il2 interleukin 2 JBrowse link NW_004955428 18,163,010 18,168,157 RGD:9068941
G Il6 interleukin 6 JBrowse link NW_004955410 25,079,835 25,084,390 RGD:9068941
RGD:11553900
G Lmna lamin A/C JBrowse link NW_004955545 2,290,076 2,310,982 RGD:9068941
G LOC102004444 beta-defensin 1-like JBrowse link NW_004955403 53,643,328 53,644,361 RGD:11554036
RGD:9068941
G LOC102021597 alpha-1-antiproteinase S-like JBrowse link NW_004955438 17,920,200 17,929,105 RGD:11553864
RGD:9068941
RGD:11553918
G LOC102021956 alpha-2-macroglobulin JBrowse link NW_004955413 6,019,457 6,062,366 RGD:11553864
RGD:9068941
RGD:11553918
G Lta4h leukotriene A4 hydrolase JBrowse link NW_004955405 32,345,005 32,377,685 RGD:11553910
RGD:9068941
G Ltb4r leukotriene B4 receptor JBrowse link NW_004955409 35,984,757 35,991,492 RGD:11553910
RGD:9068941
G Ltc4s leukotriene C4 synthase JBrowse link NW_004955408 788,856 791,505 RGD:11553910
RGD:9068941
G Mbl2 mannose binding lectin 2 JBrowse link NW_004955425 7,704,371 7,708,951 RGD:9068941
G Mecom MDS1 and EVI1 complex locus JBrowse link NW_004955448 18,259,847 18,542,085 RGD:9068941
G Muc1 mucin 1, cell surface associated JBrowse link NW_004955545 1,657,728 1,662,112 RGD:9068941
G Muc3a mucin 3A, cell surface associated JBrowse link NW_004955573 45,920 60,091 RGD:9068941
G Muc4 mucin 4, cell surface associated JBrowse link NW_004955420 12,228,801 12,274,840 RGD:9068941
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming JBrowse link NW_004955476 11,061,405 11,084,294 RGD:9068941
G Muc5b mucin 5B, oligomeric mucus/gel-forming JBrowse link NW_004955476 11,021,665 11,049,239 RGD:9068941
G Naglu N-acetyl-alpha-glucosaminidase JBrowse link NW_004955451 16,445,338 16,449,243 RGD:9068941
G Nf2 neurofibromin 2 JBrowse link NW_004955455 3,862,804 3,950,669 RGD:9068941
G Nisch nischarin JBrowse link NW_004955430 2,443,029 2,488,267 RGD:9068941
G Nos2 nitric oxide synthase 2 JBrowse link NW_004955481 5,197,957 5,232,406 RGD:9068941
G Phex phosphate regulating endopeptidase homolog X-linked JBrowse link NW_004955509 2,357,263 2,546,802 RGD:9068941
G Plau plasminogen activator, urokinase JBrowse link NW_004955437 17,995,726 18,000,542 RGD:11553864
RGD:9068941
G Pth parathyroid hormone JBrowse link NW_004955414 28,828,389 28,831,417 RGD:9068941
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link NW_004955422 19,602,930 19,612,263 RGD:9068941
G Rpl38 ribosomal protein L38 JBrowse link NW_004955553 1,129,607 1,133,896 RGD:9068941
G Sall4 spalt like transcription factor 4 JBrowse link NW_004955445 6,824,797 6,841,141 RGD:9068941
G Scgb1a1 secretoglobin family 1A member 1 JBrowse link NW_004955599 688,414 690,644 RGD:9068941
G Scn2b sodium voltage-gated channel beta subunit 2 JBrowse link NW_004955412 19,341,008 19,353,563 RGD:9068941
G Sh3pxd2b SH3 and PX domains 2B JBrowse link NW_004955408 25,103,278 25,169,934 RGD:9068941
G Tbx1 T-box transcription factor 1 JBrowse link NW_004955442 18,320,674 18,327,062 RGD:9068941
G Tgif1 TGFB induced factor homeobox 1 JBrowse link NW_004955402 7,130,809 7,138,945 RGD:9068941
G Tlr2 toll like receptor 2 JBrowse link NW_004955471 8,011,710 8,019,063 RGD:9068941
G Tlr4 toll like receptor 4 JBrowse link NW_004955419 10,190,937 10,201,896 RGD:9068941
G Tnf tumor necrosis factor JBrowse link NW_004955437 117,267 119,899 RGD:9068941
RGD:11553900
G Tp73 tumor protein p73 JBrowse link NW_004955486 7,914,608 7,961,992 RGD:9068941
G Vegfa vascular endothelial growth factor A JBrowse link NW_004955437 9,527,445 9,541,908 RGD:9068941
Acute Otitis Media term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arpc4 actin related protein 2/3 complex subunit 4 JBrowse link NW_004955561 1,314,299 1,327,300 RGD:11553828
RGD:9068941
G Cald1 caldesmon 1 JBrowse link NW_004955494 7,578,162 7,675,558 RGD:11553828
RGD:9068941
G Col3a1 collagen type III alpha 1 chain JBrowse link NW_004955403 9,720,831 9,758,019 RGD:11556224
RGD:9068941
G Dstn destrin, actin depolymerizing factor JBrowse link NW_004955415 26,567,457 26,598,978 RGD:11553828
RGD:9068941
G Fn1 fibronectin 1 JBrowse link NW_004955457 629,599 694,948 RGD:11556224
RGD:9068941
G Lcp1 lymphocyte cytosolic protein 1 JBrowse link NW_004955518 3,815,181 3,863,440 RGD:11553828
RGD:9068941
G LOC102005867 protein S100-A8 JBrowse link NW_004955592 72,594 73,659 RGD:11553828
G Ncf2 neutrophil cytosolic factor 2 JBrowse link NW_004955406 22,355,717 22,384,746 RGD:11553828
RGD:9068941
G S100a9 S100 calcium binding protein A9 JBrowse link NW_004955592 90,647 93,842 RGD:11553828
RGD:9068941
mastoiditis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link NW_004955422 19,602,930 19,612,263 RGD:9068941
G Tlr2 toll like receptor 2 JBrowse link NW_004955471 8,011,710 8,019,063 RGD:9068941
G Tlr4 toll like receptor 4 JBrowse link NW_004955419 10,190,937 10,201,896 RGD:9068941
Otitis Media with Effusion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C3 complement C3 JBrowse link NW_004955495 2,796,601 2,824,233 RGD:9068941
G Flt1 fms related tyrosine kinase 1 JBrowse link NW_004955497 7,653,309 7,831,737 RGD:9068941
G Glb1 galactosidase beta 1 JBrowse link NW_004955421 230,957 311,504 RGD:11557999
RGD:9068941
G Gusb glucuronidase beta JBrowse link NW_004955456 8,377,161 8,392,298 RGD:11557999
RGD:9068941
G Ifng interferon gamma JBrowse link NW_004955458 14,643,333 14,648,020 RGD:9068941
G Il1b interleukin 1 beta JBrowse link NW_004955470 1,486,936 1,491,888 RGD:9068941
RGD:11554174
G Il4 interleukin 4 JBrowse link NW_004955408 4,058,052 4,065,999 RGD:9068941
G Il4r interleukin 4 receptor JBrowse link NW_004955493 5,546,340 5,580,745 RGD:9068941
G Kdr kinase insert domain receptor JBrowse link NW_004955447 15,810,816 15,851,702 RGD:9068941
G LOC102021597 alpha-1-antiproteinase S-like JBrowse link NW_004955438 17,920,200 17,929,105 RGD:11560528
RGD:9068941
G LOC102021956 alpha-2-macroglobulin JBrowse link NW_004955413 6,019,457 6,062,366 RGD:11560528
RGD:9068941
G Ltf lactotransferrin JBrowse link NW_004955420 25,580,449 25,604,277 RGD:11554025
RGD:9068941
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming JBrowse link NW_004955476 11,061,405 11,084,294 RGD:9068941
G Muc5b mucin 5B, oligomeric mucus/gel-forming JBrowse link NW_004955476 11,021,665 11,049,239 RGD:9068941
G Oxgr1 oxoglutarate receptor 1 JBrowse link NW_004955404 13,337,607 13,344,789 RGD:9068941
G Ptafr platelet activating factor receptor JBrowse link NW_004955452 7,309,854 7,345,579 RGD:11554333
G Tlr2 toll like receptor 2 JBrowse link NW_004955471 8,011,710 8,019,063 RGD:9068941
G Tlr4 toll like receptor 4 JBrowse link NW_004955419 10,190,937 10,201,896 RGD:9068941
G Tnf tumor necrosis factor JBrowse link NW_004955437 117,267 119,899 RGD:9068941
G Vegfa vascular endothelial growth factor A JBrowse link NW_004955437 9,527,445 9,541,908 RGD:9068941
suppurative otitis media term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alb albumin JBrowse link NW_004955447 9,327 21,212 RGD:11556250
RGD:9068941
G Ifng interferon gamma JBrowse link NW_004955458 14,643,333 14,648,020 RGD:9068941
G LOC102021956 alpha-2-macroglobulin JBrowse link NW_004955413 6,019,457 6,062,366 RGD:11556250
RGD:9068941
G Tlr2 toll like receptor 2 JBrowse link NW_004955471 8,011,710 8,019,063 RGD:9068941
G Tlr4 toll like receptor 4 JBrowse link NW_004955419 10,190,937 10,201,896 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 10984
    sensory system disease 3851
      auditory system disease 595
        middle ear disease 90
          otitis media 83
            Acute Otitis Media 9
            Otitis Media with Effusion 20
            adhesive otitis media 0
            mastoiditis 3
            middle ear cholesterol granuloma 0
            non-suppurative otitis media + 0
            petrositis 0
            suppurative otitis media + 5
Path 2
Term Annotations click to browse term
  disease 10984
    disease of anatomical entity 10634
      nervous system disease 8429
        sensory system disease 3851
          Otorhinolaryngologic Diseases 942
            auditory system disease 595
              middle ear disease 90
                otitis media 83
                  Acute Otitis Media 9
                  Otitis Media with Effusion 20
                  adhesive otitis media 0
                  mastoiditis 3
                  middle ear cholesterol granuloma 0
                  non-suppurative otitis media + 0
                  petrositis 0
                  suppurative otitis media + 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.