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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:kidney failure
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Accession:DOID:1074 term browser browse the term
Definition:A kidney disease characterized by the failure of the kidneys to adequately filter waste products from the blood. (DO)
Synonyms:exact_synonym: Kidney Insufficiencies;   Kidney Insufficiency;   Renal Failure;   Renal Failures;   Renal Insufficiencies;   kidney failures;   renal unsufficiency
 primary_id: MESH:D051437
 xref: ICD10CM:N19;   ICD9CM:586;   NCI:C4376
For additional species annotation, visit the Alliance of Genome Resources.



show annotations for term's descendants           Sort by:
 
kidney failure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9259580 NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790
JBrowse link
G Acmsd amino carboxymuconate semialdehyde decarboxylase ISO RGD PMID:10966936 RGD:13831124 NCBI chr 1:127,657,150...127,695,301
Ensembl chr 1:127,657,150...127,695,715
JBrowse link
G Adam10 a disintegrin and metallopeptidase domain 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:32715474 NCBI chr 9:70,586,133...70,687,511
Ensembl chr 9:70,586,279...70,687,511
JBrowse link
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) ISO CTD Direct Evidence: marker/mechanism CTD PMID:9259580 NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445
JBrowse link
G Ambp alpha 1 microglobulin/bikunin precursor ISO RGD PMID:18046670 RGD:6904142 NCBI chr 4:63,061,512...63,072,409
Ensembl chr 4:63,061,512...63,073,036
JBrowse link
G Apoe apolipoprotein E ISO CTD Direct Evidence: marker/mechanism CTD PMID:20842518 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113
JBrowse link
G Cd80 CD80 antigen ISO RGD PMID:16893502 RGD:6902939 NCBI chr16:38,277,793...38,316,682
Ensembl chr16:38,275,923...38,316,697
JBrowse link
G Crp C-reactive protein, pentraxin-related severity ISO associated with Anemia, Sickle Cell; protein:increased expression:serum RGD PMID:20710104 RGD:6907441 NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598
JBrowse link
G Cyba cytochrome b-245, alpha polypeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:23325087 NCBI chr 8:123,151,510...123,159,679
Ensembl chr 8:123,151,515...123,159,669
JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8164439 NCBI chr 2:170,324,877...170,339,065
Ensembl chr 2:170,324,628...170,339,065
JBrowse link
G Drd1 dopamine receptor D1 ISO DNA:polymorphism:5' utr:g.-94G>A (human) RGD PMID:19675531 RGD:7248447 NCBI chr13:54,205,202...54,209,677
Ensembl chr13:54,205,202...54,209,724
JBrowse link
G Edn1 endothelin 1 onset ISO protein:increased expression:kidney (rat)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:7967349 PMID:20888384 RGD:4144130 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466
JBrowse link
G Epo erythropoietin ISO CTD Direct Evidence: therapeutic CTD PMID:22013135 NCBI chr 5:137,481,282...137,484,078
Ensembl chr 5:137,481,282...137,531,504
JBrowse link
G Ercc1 excision repair cross-complementing rodent repair deficiency, complementation group 1 treatment ISO associated with Ovarian Neoplasms;DNA:SNPs: :8092C>A, 19007T>C (human) RGD PMID:19786980 RGD:5688741 NCBI chr 7:19,075,769...19,090,449
Ensembl chr 7:19,078,703...19,090,449
JBrowse link
G Gfer growth factor, augmenter of liver regeneration treatment ISO associated with liver transplant; RGD PMID:18929838 RGD:9685774 NCBI chr17:24,912,163...24,916,133
Ensembl chr17:24,912,161...24,915,130
JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit ISO associated with Hypertension;protein:increased expression:kidney RGD PMID:15583217 RGD:1626324 NCBI chr12:73,948,098...73,994,328
Ensembl chr12:73,948,149...73,994,304
JBrowse link
G Idh2 isocitrate dehydrogenase 2 (NADP+), mitochondrial ISO CTD Direct Evidence: marker/mechanism CTD PMID:27469509 NCBI chr 7:79,744,594...79,768,356
Ensembl chr 7:79,744,594...79,765,140
JBrowse link
G Ifng interferon gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:3091246 PMID:8289579 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Il1b interleukin 1 beta IEP
ISO
mRNA, protein:increased expression:kidney (mouse) RGD PMID:21907489 PMID:20722564 RGD:7175305, RGD:7175345 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Ins2 insulin II ISO CTD Direct Evidence: marker/mechanism CTD PMID:8606734 PMID:9861226 NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118
JBrowse link
G Kl klotho ISO RGD PMID:10892340 RGD:1581732 NCBI chr 5:150,876,072...150,917,282
Ensembl chr 5:150,876,072...150,917,282
JBrowse link
G Lepr leptin receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:29988851 NCBI chr 4:101,574,393...101,676,375
Ensembl chr 4:101,574,601...101,672,549
JBrowse link
G Mme membrane metallo endopeptidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:10485324 NCBI chr 3:63,202,632...63,291,134
Ensembl chr 3:63,148,958...63,293,451
JBrowse link
G Mt1 metallothionein 1 ISO associated with Cadmium Poisoning;mRNA:increased expression:kidney RGD PMID:16226777 RGD:6483854 NCBI chr 8:94,905,214...94,906,955
Ensembl chr 8:94,905,710...94,906,955
JBrowse link
G Mt2 metallothionein 2 ISO associated with Cadmium Poisoning;mRNA:increased expression:kidney RGD PMID:16226777 RGD:6483854 NCBI chr 8:94,899,246...94,900,195
Ensembl chr 8:94,899,292...94,900,196
JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO DNA:transition:cds:g.677C>T (human) RGD PMID:20433440 RGD:6893515 NCBI chr 4:148,123,534...148,144,019
Ensembl chr 4:148,123,534...148,144,008
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase treatment ISO RGD PMID:25594614 RGD:13781896 NCBI chr12:32,870,334...32,903,368
Ensembl chr12:32,869,544...32,903,348
JBrowse link
G Notch2 notch 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:32715474 NCBI chr 3:97,920,854...98,057,683
Ensembl chr 3:97,920,843...98,057,677
JBrowse link
G Nox4 NADPH oxidase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23325087 NCBI chr 7:86,893,638...87,047,918
Ensembl chr 7:86,895,304...87,047,918
JBrowse link
G Nphs1 nephrosis 1, nephrin severity ISO protein:decreased expression:kidney (rat) RGD PMID:18346151 RGD:38599007 NCBI chr 7:30,157,259...30,188,048
Ensembl chr 7:30,157,740...30,186,648
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 ISO RGD PMID:19833176 RGD:10413912 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
JBrowse link
G Phex phosphate regulating endopeptidase homolog, X-linked ISO mRNA:increased expression:parathroid gland,tibia: RGD PMID:14693675 RGD:11556273 NCBI chr  X:155,945,071...156,198,282
Ensembl chr  X:155,945,071...156,198,308
JBrowse link
G Pkd1 polycystin 1, transient receptor potential channel interacting ISO ClinVar Annotator: match by term: Renal failure ClinVar NCBI chr17:24,767,657...24,815,488
Ensembl chr17:24,768,808...24,815,482
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:28182703 NCBI chr 6:115,337,840...115,467,365
Ensembl chr 6:115,337,912...115,467,360
JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha ISO RGD PMID:22076434 RGD:7242044 NCBI chr 5:51,611,591...52,273,337
Ensembl chr 5:51,611,592...51,725,068
JBrowse link
G Ren1 renin 1 structural IMP RGD PMID:28533331 RGD:39939034 NCBI chr 1:133,278,412...133,288,058
Ensembl chr 1:133,278,248...133,288,063
JBrowse link
G Rhcg Rhesus blood group-associated C glycoprotein ISO protein:altered localization RGD PMID:17652373 RGD:9850158 NCBI chr 7:79,243,111...79,267,405
Ensembl chr 7:79,243,111...79,267,405
JBrowse link
G Serpinf1 serine (or cysteine) peptidase inhibitor, clade F, member 1 ISO protein:increased expression:plasma (human) RGD PMID:16828495 RGD:36174008 NCBI chr11:75,300,855...75,313,449
Ensembl chr11:75,300,595...75,313,527
JBrowse link
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 ISO mRNA, protein:decreased expression:kidney cortex RGD PMID:21167265 RGD:7243878 NCBI chr17:12,803,076...12,847,376
Ensembl chr17:12,803,019...12,847,375
JBrowse link
G Slco4c1 solute carrier organic anion transporter family, member 4C1 ISO mRNA:decreased expression:kidney RGD PMID:14993604 RGD:1303977 NCBI chr 1:96,744,918...96,800,027
Ensembl chr 1:96,743,995...96,799,896
JBrowse link
G Spp1 secreted phosphoprotein 1 ISO In type 2 diabetic patients RGD PMID:21034455 RGD:6903271 NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916
JBrowse link
G Tbxa2r thromboxane A2 receptor treatment ISO associated with Cholestasis; RGD PMID:9893136 RGD:11059601 NCBI chr10:81,164,102...81,171,008
Ensembl chr10:81,164,565...81,171,006
JBrowse link
G Tlr2 toll-like receptor 2 ISO RGD PMID:16177646 RGD:7241085 NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074
JBrowse link
G Tlr4 toll-like receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:27585667 PMID:16177646 RGD:7241085 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521
JBrowse link
G Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b severity ISO associated with Neoplasms, Plasma Cell RGD PMID:9650354 RGD:7245537 NCBI chr 4:144,938,938...144,973,453
Ensembl chr 4:144,940,033...144,973,440
JBrowse link
G Tsc1 TSC complex subunit 1 ISO ClinVar Annotator: match by term: Renal failure ClinVar PMID:10227394 PMID:10570911 PMID:15798777 PMID:23341583 PMID:25741868 More... NCBI chr 2:28,531,005...28,581,184
Ensembl chr 2:28,531,240...28,581,179
JBrowse link
G Wfdc6a WAP four-disulfide core domain 6A ISO CTD Direct Evidence: marker/mechanism CTD PMID:16436767 NCBI chr 2:164,421,439...164,427,704
Ensembl chr 2:164,421,439...164,427,367
JBrowse link
G Xdh xanthine dehydrogenase treatment IMP
IAGP
associated with Hyperuricemia
DNA:nonsense mutation:CDS
RGD PMID:23137955 PMID:19667249 PMID:23024809 RGD:7247633, RGD:7247649, RGD:7247636 NCBI chr17:74,190,890...74,257,369
Ensembl chr17:74,190,890...74,257,191
JBrowse link
acute kidney failure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:23052191 NCBI chr 6:121,612,920...121,656,197
Ensembl chr 6:121,612,335...121,656,186
JBrowse link
G Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 treatment ISO RGD PMID:24502693 RGD:11039053 NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790
JBrowse link
G Adrb2 adrenergic receptor, beta 2 treatment ISO associated with endotoxemia; protein:increased expression:kidney
associated with Endotoxemia;
associated with Bacteremia;
RGD PMID:14747378 PMID:19020966 PMID:19887504 PMID:14747378 RGD:7175276, RGD:7175283, RGD:7175281, RGD:7175276 NCBI chr18:62,310,784...62,313,052
Ensembl chr18:62,310,887...62,313,030
JBrowse link
G Afm afamin ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chr 5:90,666,808...90,701,403
Ensembl chr 5:90,666,791...90,701,402
JBrowse link
G Ager advanced glycosylation end product-specific receptor ISO RGD PMID:21811803 RGD:7243868 NCBI chr17:34,816,545...34,819,911
Ensembl chr17:34,816,836...34,819,910
JBrowse link
G Ahsg alpha-2-HS-glycoprotein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chr16:22,710,765...22,718,201
Ensembl chr16:22,710,027...22,718,199
JBrowse link
G Alad aminolevulinate, delta-, dehydratase ISO protein:decreased activity:kidney (rat) RGD PMID:19484701 RGD:4144146 NCBI chr 4:62,424,221...62,438,300
Ensembl chr 4:62,427,406...62,438,155
JBrowse link
G Alb albumin ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:2048579 PMID:21259293 PMID:24361871 PMID:28885000 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461
JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO RGD PMID:19194548 RGD:2317536 NCBI chr 6:116,387,030...116,438,139
Ensembl chr 6:116,387,038...116,438,139
JBrowse link
G Ambp alpha 1 microglobulin/bikunin precursor ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD
PMID:8963945 PMID:28885000 PMID:8963945 RGD:6904218 NCBI chr 4:63,061,512...63,072,409
Ensembl chr 4:63,061,512...63,073,036
JBrowse link
G Amn amnionless ISO CTD Direct Evidence: therapeutic CTD PMID:20514524 NCBI chr12:111,237,530...111,242,860
Ensembl chr12:111,237,529...111,242,860
JBrowse link
G Anxa1 annexin A1 treatment ISO RGD PMID:22101490 RGD:7421583 NCBI chr19:20,350,798...20,368,035
Ensembl chr19:20,350,792...20,368,308
JBrowse link
G Ar androgen receptor ISO RGD PMID:24503548 RGD:11570523 NCBI chr  X:97,192,363...97,366,824
Ensembl chr  X:97,192,375...97,366,821
JBrowse link
G Arg1 arginase, liver ISO mRNA:decreased expression:renal tubule (rat) RGD PMID:12371970 RGD:631989 NCBI chr10:24,791,105...24,803,368
Ensembl chr10:24,791,119...24,803,382
JBrowse link
G Arg2 arginase type II ISO mRNA:decreased expression:renal tubule (rat) RGD PMID:12371970 RGD:631989 NCBI chr12:79,177,562...79,203,075
Ensembl chr12:79,177,551...79,203,075
JBrowse link
G Atp5b ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit ISO
EXP
CTD Direct Evidence: marker/mechanism CTD PMID:25666834 NCBI chr10:127,919,176...127,926,257
Ensembl chr10:127,919,142...127,926,260
JBrowse link
G Avp arginine vasopressin ISO CTD Direct Evidence: marker/mechanism CTD PMID:2139164 NCBI chr 2:130,422,540...130,424,508
Ensembl chr 2:130,422,540...130,424,474
JBrowse link
G Avpr1a arginine vasopressin receptor 1A ISO RGD PMID:17347933 RGD:2300348 NCBI chr10:122,284,404...122,289,358
Ensembl chr10:122,284,404...122,289,357
JBrowse link
G B2m beta-2 microglobulin ISO protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:2689182 PMID:22005293 PMID:28885000 PMID:19536607 RGD:6482685 NCBI chr 2:121,978,168...121,983,563
Ensembl chr 2:121,978,167...121,983,564
JBrowse link
G Bad BCL2-associated agonist of cell death treatment ISO RGD PMID:20037173 RGD:10053672 NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267
JBrowse link
G Bax BCL2-associated X protein treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:20623750 PMID:20037173 RGD:10053672 NCBI chr 7:45,111,119...45,116,344
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 ISO protein:increased expression:kidney RGD PMID:20037173 RGD:10053672 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bcl2l1 BCL2-like 1 ISO protein:increased expression:kidney RGD PMID:20037173 RGD:10053672 NCBI chr 2:152,600,652...152,675,723
Ensembl chr 2:152,622,588...152,673,648
JBrowse link
G Bdkrb2 bradykinin receptor, beta 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24975837 NCBI chr12:105,529,431...105,561,503
Ensembl chr12:105,529,485...105,561,496
JBrowse link
G C3 complement component 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136
JBrowse link
G Capn1 calpain 1 treatment ISO associated with Rhabdomyolysis; RGD PMID:24158126 RGD:13792553 NCBI chr19:6,038,573...6,065,855
Ensembl chr19:6,038,573...6,065,927
JBrowse link
G Casp1 caspase 1 ISO RGD PMID:16557226 RGD:2293624 NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290
JBrowse link
G Ccl11 chemokine (C-C motif) ligand 11 IEP protein:increased expression:kidney RGD PMID:22778179 RGD:7247739 NCBI chr11:81,948,658...81,953,781
Ensembl chr11:81,948,649...81,953,781
JBrowse link
G Ccl3 chemokine (C-C motif) ligand 3 ISO RGD PMID:20482449 RGD:6906908 NCBI chr11:83,538,669...83,540,204
Ensembl chr11:83,538,670...83,540,181
JBrowse link
G Ccl5 chemokine (C-C motif) ligand 5 IEP protein:increased secretion:serum (mouse) RGD PMID:19508392 RGD:4889990 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344
JBrowse link
G Ccr5 chemokine (C-C motif) receptor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26055553 NCBI chr 9:123,921,557...123,934,153
Ensembl chr 9:123,921,580...123,947,736
JBrowse link
G Cct7 chaperonin containing Tcp1, subunit 7 (eta) ISO CTD Direct Evidence: marker/mechanism CTD PMID:31825490 NCBI chr 6:85,428,487...85,445,459
Ensembl chr 6:85,428,496...85,445,457
JBrowse link
G Cd44 CD44 antigen ISO CTD Direct Evidence: marker/mechanism CTD PMID:23052191 NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B ISO protein:decreased expression:kidney RGD PMID:16557226 RGD:2293624 NCBI chr 6:134,897,364...134,902,488
Ensembl chr 6:134,897,364...134,902,476
JBrowse link
G Ces1c carboxylesterase 1C EXP CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chr 8:93,825,643...93,857,911
Ensembl chr 8:93,825,643...93,857,911
JBrowse link
G Clu clusterin ISO protein:increased expression:urine
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:20118187 PMID:20623750 PMID:22005293 PMID:23052191 PMID:24361871 More... RGD:7245501 NCBI chr14:66,205,932...66,218,997
Ensembl chr14:66,205,932...66,218,996
JBrowse link
G Cp ceruloplasmin ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chr 3:20,011,097...20,063,914
Ensembl chr 3:20,011,218...20,063,309
JBrowse link
G Crp C-reactive protein, pentraxin-related ISO protein:increased expression:serum
associated with Myocardial Infarction;
RGD PMID:22551254 PMID:22694718 RGD:6903282, RGD:6906888 NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598
JBrowse link
G Csf1 colony stimulating factor 1 (macrophage) IMP RGD PMID:23143303 RGD:7257565 NCBI chr 3:107,648,364...107,668,048
Ensembl chr 3:107,648,364...107,667,785
JBrowse link
G Csf1r colony stimulating factor 1 receptor IMP RGD PMID:23143303 RGD:7257565 NCBI chr18:61,238,644...61,264,211
Ensembl chr18:61,233,670...61,265,221
JBrowse link
G Cst3 cystatin C ISO CTD Direct Evidence: marker/mechanism CTD PMID:22005293 PMID:28885000 NCBI chr 2:148,713,642...148,717,432
Ensembl chr 2:148,713,642...148,717,612
JBrowse link
G Cxcl1 chemokine (C-X-C motif) ligand 1 IEP mRNA:increased expression:kidney, liver, spleen RGD PMID:21677145 RGD:7175314 NCBI chr 5:91,039,104...91,040,980
Ensembl chr 5:91,039,100...91,040,974
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 treatment IDA RGD PMID:19890363 PMID:18495746 RGD:7257732, RGD:7257735 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 treatment IDA RGD PMID:23981375 PMID:18495746 RGD:7257727, RGD:7257735 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 ISO RGD PMID:6223803 RGD:2307326 NCBI chr10:126,884,115...126,891,897
Ensembl chr10:126,884,119...126,888,875
JBrowse link
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19814645 NCBI chr19:39,378,000...39,451,547
Ensembl chr19:39,378,000...39,451,519
JBrowse link
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19814645 NCBI chr19:39,049,450...39,082,392
Ensembl chr19:39,049,459...39,082,388
JBrowse link
G Cyp2c66 cytochrome P450, family 2, subfamily c, polypeptide 66 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19814645 NCBI chr19:39,102,342...39,175,200
Ensembl chr19:39,102,342...39,175,516
JBrowse link
G Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19814645 NCBI chr15:82,254,728...82,264,461
Ensembl chr15:82,254,728...82,264,461
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 treatment ISO RGD PMID:24717297 PMID:24412858 RGD:14700914, RGD:14700920 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 ISO Protein:increased expression:renal tubule epithelium RGD PMID:15476864 RGD:1599736 NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157
JBrowse link
G Ece1 endothelin converting enzyme 1 ISO RGD PMID:11043448 PMID:10073607 RGD:7244180, RGD:7244185 NCBI chr 4:137,589,548...137,692,540
Ensembl chr 4:137,589,548...137,692,540
JBrowse link
G Edn1 endothelin 1 IEP
ISO
mRNA, protein:increased expression:kidney (mouse)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:9788586 PMID:19967049 RGD:4144852 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466
JBrowse link
G Egf epidermal growth factor ISO mRNA:decreased expression:kidney RGD PMID:20482449 PMID:11340354 RGD:6906908, RGD:10395241 NCBI chr 3:129,471,223...129,548,971
Ensembl chr 3:129,471,214...129,548,965
JBrowse link
G Egfr epidermal growth factor receptor ISO mRNA:increased expression:kidney
CTD Direct Evidence: therapeutic
CTD
RGD
PMID:14638913 PMID:11340354 RGD:10395241 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158
JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 ISO mRNA, protein:decreased expression:kidney RGD PMID:19349364 RGD:11252083 NCBI chr 8:125,635,326...125,675,993
Ensembl chr 8:125,635,326...125,676,063
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 ISO mRNA, protein:decreased expression:kidney RGD PMID:19349364 RGD:11252083 NCBI chr12:54,225,767...54,250,660
Ensembl chr12:54,225,767...54,250,646
JBrowse link
G Epas1 endothelial PAS domain protein 1 treatment ISO RGD PMID:16762988 RGD:10395386 NCBI chr17:87,061,292...87,140,838
Ensembl chr17:87,061,128...87,140,838
JBrowse link
G Ephx2 epoxide hydrolase 2, cytoplasmic ISO CTD Direct Evidence: therapeutic CTD PMID:26165641 NCBI chr14:66,321,821...66,361,971
Ensembl chr14:66,321,823...66,361,949
JBrowse link
G Epo erythropoietin treatment ISO CTD Direct Evidence: therapeutic CTD
RGD
PMID:21847101 PMID:24561306 PMID:22209169 PMID:22235348 RGD:10400913, RGD:11041660 NCBI chr 5:137,481,282...137,484,078
Ensembl chr 5:137,481,282...137,531,504
JBrowse link
G Fas Fas (TNF receptor superfamily member 6) ISO protein:increased expression:renal tubule (rat) RGD PMID:21374789 RGD:8663469 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
JBrowse link
G Fga fibrinogen alpha chain ISO mRNA:increased expression:kidney (rat) RGD PMID:15805072 RGD:9685024 NCBI chr 3:82,933,460...82,940,934
Ensembl chr 3:82,933,383...82,940,934
JBrowse link
G Fis1 fission, mitochondrial 1 ISO protein:decreased expression:kidney (rat) RGD PMID:26480480 RGD:12910862 NCBI chr 5:136,982,129...136,995,088
Ensembl chr 5:136,982,129...136,995,088
JBrowse link
G Fn1 fibronectin 1 ISO protein:increased expression:kidney RGD PMID:12884040 PMID:11768240 RGD:7205684, RGD:729934 NCBI chr 1:71,624,632...71,692,439
Ensembl chr 1:71,624,679...71,692,359
JBrowse link
G Fstl1 follistatin-like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20861081 NCBI chr16:37,597,417...37,656,878
Ensembl chr16:37,597,235...37,656,876
JBrowse link
G G6pdx glucose-6-phosphate dehydrogenase X-linked ISO CTD Direct Evidence: marker/mechanism CTD PMID:602954 PMID:734759 PMID:4794122 NCBI chr  X:73,453,089...73,472,486
Ensembl chr  X:73,453,089...73,472,800
JBrowse link
G Gas6 growth arrest specific 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19564549 NCBI chr 8:13,515,374...13,544,535
Ensembl chr 8:13,515,374...13,544,490
JBrowse link
G Gatm glycine amidinotransferase (L-arginine:glycine amidinotransferase) ISO protein:decreased activity:kidney (rat) RGD PMID:2752493 RGD:1599823 NCBI chr 2:122,424,954...122,441,758
Ensembl chr 2:122,424,948...122,441,784
JBrowse link
G Gc vitamin D binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chr 5:89,565,370...89,605,757
Ensembl chr 5:89,565,381...89,605,757
JBrowse link
G Gfer growth factor, augmenter of liver regeneration treatment ISO protein:increased expression:cortex of kidney,renal medulla:
CTD Direct Evidence: therapeutic
CTD
RGD
PMID:20030531 PMID:20030531 PMID:20030531 RGD:9685736, RGD:9685736 NCBI chr17:24,912,163...24,916,133
Ensembl chr17:24,912,161...24,915,130
JBrowse link
G Ghrl ghrelin IDA RGD PMID:19625378 RGD:7242430 NCBI chr 6:113,693,080...113,696,872
Ensembl chr 6:113,693,080...113,696,841
JBrowse link
G Got2 glutamatic-oxaloacetic transaminase 2, mitochondrial ISO protein:decreased activity:kidney (rat) RGD PMID:23924727 RGD:13506245 NCBI chr 8:96,590,761...96,615,029
Ensembl chr 8:96,590,762...96,615,175
JBrowse link
G Gpnmb glycoprotein (transmembrane) nmb ISO CTD Direct Evidence: marker/mechanism CTD PMID:23052191 NCBI chr 6:49,013,449...49,044,413
Ensembl chr 6:49,013,480...49,047,863
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:22785175 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446
JBrowse link
G Gsr glutathione reductase ISO
IEP
glycerol-induced
protein:decreased activity:kidney:
RGD PMID:1870354 PMID:22286819 RGD:7257559, RGD:7257585 NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191
JBrowse link
G Gstm2 glutathione S-transferase, mu 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20623750 NCBI chr 3:107,889,018...107,893,736
Ensembl chr 3:107,889,018...107,893,769
JBrowse link
G Gstp1 glutathione S-transferase, pi 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:20623750 PMID:20798258 RGD:6903954 NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 ISO
IEP
protein:increased expression:urine
CTD Direct Evidence: marker/mechanism
protein:increased expression:urine:
associated with Pyelonephritis;protein:increased expression:urine:
CTD
RGD
PMID:20118187 PMID:21259293 PMID:21835770 PMID:22005293 PMID:23052191 More... RGD:7244370, RGD:7245495, RGD:7245472 NCBI chr11:46,630,644...46,670,405
Ensembl chr11:46,625,907...46,670,405
JBrowse link
G Hbegf heparin-binding EGF-like growth factor ISO mRNA:increased expression:kidney
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:7635938 PMID:11340354 RGD:10395241 NCBI chr18:36,637,980...36,648,858
Ensembl chr18:36,637,980...36,648,858
JBrowse link
G Hdac2 histone deacetylase 2 treatment IEP associated with sepsis; RGD PMID:22933299 RGD:9590257 NCBI chr10:36,850,293...36,877,885
Ensembl chr10:36,850,540...36,877,885
JBrowse link
G Hdac3 histone deacetylase 3 ISO RGD PMID:21416250 RGD:10047111 NCBI chr18:38,070,024...38,088,073
Ensembl chr18:38,068,897...38,088,069
JBrowse link
G Hdac5 histone deacetylase 5 treatment IEP
ISO
associated with sepsis; RGD PMID:22933299 PMID:21416250 RGD:9590257, RGD:10047111 NCBI chr11:102,086,573...102,120,998
Ensembl chr11:102,085,258...102,120,992
JBrowse link
G Hes1 hes family bHLH transcription factor 1 ISO mRNA:increased expression:kidney collecting duct (rat)
protein:increased expression:kidney tubule (rat)
RGD PMID:24397211 PMID:24325066 RGD:9685383, RGD:9685389 NCBI chr16:29,884,175...29,886,614
Ensembl chr16:29,883,202...29,886,614
JBrowse link
G Hexb hexosaminidase B ISO CTD Direct Evidence: marker/mechanism CTD PMID:22005293 NCBI chr13:97,312,839...97,334,865
Ensembl chr13:97,312,839...97,334,865
JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit treatment ISO mRNA:increased expression:renal cortex (rat) RGD PMID:18593636 PMID:16762988 PMID:15673301 RGD:9068894, RGD:10395386, RGD:10395376 NCBI chr12:73,948,098...73,994,328
Ensembl chr12:73,948,149...73,994,304
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase IMP associated with Sepsis RGD PMID:16557230 RGD:5508471 NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444
JBrowse link
G Hmox1 heme oxygenase 1 treatment ISO associated with Sepsis
CTD Direct Evidence: therapeutic
CTD
RGD
PMID:21048024 PMID:23807243 RGD:10755583 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Hp haptoglobin ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:28885000 PMID:19270397 RGD:11041863 NCBI chr 8:110,301,760...110,305,804
Ensembl chr 8:110,301,760...110,305,804
JBrowse link
G Hpx hemopexin ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chr 7:105,240,818...105,249,323
Ensembl chr 7:105,240,820...105,249,344
JBrowse link
G Hspa1a heat shock protein 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:12690470 PMID:19546256 NCBI chr17:35,188,335...35,191,132
Ensembl chr17:35,188,166...35,191,132
JBrowse link
G Hspa8 heat shock protein 8 ISO protein:increased expression:kidney, lysosome (rat) RGD PMID:14966137 RGD:7242786 NCBI chr 9:40,712,572...40,716,498
Ensembl chr 9:40,712,280...40,721,383
JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment ISO RGD PMID:22659586 RGD:7175102 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
JBrowse link
G Igf1 insulin-like growth factor 1 ISO CTD Direct Evidence: therapeutic CTD PMID:7540432 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904
JBrowse link
G Igf1r insulin-like growth factor I receptor ISO mRNA: decreased expression: kidney: both cortex and medulla RGD PMID:9767523 RGD:7242908 NCBI chr 7:67,601,486...67,883,416
Ensembl chr 7:67,602,575...67,883,416
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 ISO CTD Direct Evidence: therapeutic CTD PMID:7540432 NCBI chr11:7,147,787...7,152,546
Ensembl chr11:7,147,782...7,152,546
JBrowse link
G Il10 interleukin 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18460982 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Il18 interleukin 18 IMP RGD PMID:11342578 RGD:6893450 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140
JBrowse link
G Il1a interleukin 1 alpha IMP RGD PMID:21716595 RGD:6907069 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
JBrowse link
G Il1b interleukin 1 beta ISO
IEP
IDA
mRNA:increased expression:kidney, liver, spleen (mouse)
protein:increased expression:kidney (rat)
RGD PMID:22750969 PMID:21677145 PMID:22286667 PMID:22659586 RGD:7175094, RGD:7175314, RGD:7175258, RGD:7175102 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO
IDA
associated with Sepsis
associated with Asphyxia; rat model treated with human protein
RGD PMID:16763508 PMID:14610321 PMID:16259926 RGD:6907360, RGD:6907375, RGD:6907369 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506
JBrowse link
G Il20 interleukin 20 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18496552 NCBI chr 1:130,834,722...130,839,033
Ensembl chr 1:130,834,722...130,839,188
JBrowse link
G Il6 interleukin 6 ISO associated with Acute Lung Injury;protein:increased expression:plasma
CTD Direct Evidence: therapeutic
CTD
RGD
PMID:21570986 PMID:18074478 RGD:5128661 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Ins2 insulin II ISO CTD Direct Evidence: marker/mechanism CTD PMID:12243603 NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118
JBrowse link
G Jak2 Janus kinase 2 treatment IEP associated with Carcinoma, Lewis Lung, human cells in mouse model RGD PMID:31250048 RGD:149735351 NCBI chr19:29,229,006...29,290,495
Ensembl chr19:29,229,228...29,290,480
JBrowse link
G Klk1 kallikrein 1 ISO CTD Direct Evidence: therapeutic CTD PMID:18227104 NCBI chr 7:43,874,784...43,879,046
Ensembl chr 7:43,874,784...43,879,042
JBrowse link
G Kng2 kininogen 2 ISO CTD Direct Evidence: therapeutic CTD PMID:513486 PMID:3015452 NCBI chr16:22,804,602...22,847,851
Ensembl chr16:22,804,604...22,848,232
JBrowse link
G Lcn2 lipocalin 2 ISO protein:increased expression:urine
associated with open cardiac surgeries;protein:increased expression:urine:
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:20623750 PMID:22005293 PMID:23052191 PMID:27888128 PMID:28885000 More... RGD:7244370, RGD:126781714, RGD:125973912 NCBI chr 2:32,274,649...32,277,751
Ensembl chr 2:32,274,645...32,278,264
JBrowse link
G Lgals3 lectin, galactose binding, soluble 3 ISO mRNA:increased expression:kidney RGD PMID:10980121 RGD:9685228 NCBI chr14:47,611,317...47,623,624
Ensembl chr14:47,605,208...47,623,617
JBrowse link
G Lrg1 leucine-rich alpha-2-glycoprotein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34677723 NCBI chr17:56,426,678...56,428,946
Ensembl chr17:56,426,678...56,429,001
JBrowse link
G Lrp2 low density lipoprotein receptor-related protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29286200 NCBI chr 2:69,254,679...69,416,373
Ensembl chr 2:69,254,684...69,416,409
JBrowse link
G Mb myoglobin ISO protein: increased expression: serum RGD PMID:23497406 PMID:9822635 RGD:7244253, RGD:7244259 NCBI chr15:76,899,687...76,934,868
Ensembl chr15:76,899,687...76,934,870
JBrowse link
G Met met proto-oncogene ISO protein:increased expression:renal parenchyma (rat) RGD PMID:17940345 RGD:2317469 NCBI chr 6:17,463,351...17,573,979
Ensembl chr 6:17,463,799...17,573,979
JBrowse link
G Mfn1 mitofusin 1 ISO protein:decreased expression:kidney (rat) RGD PMID:26480480 RGD:12910862 NCBI chr 3:32,583,594...32,633,374
Ensembl chr 3:32,583,614...32,633,388
JBrowse link
G Mir10a microRNA 10a ISO CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr11:96,207,991...96,208,100
Ensembl chr11:96,207,991...96,208,100
JBrowse link
G Mir122 microRNA 122 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr18:65,381,932...65,381,997
Ensembl chr18:65,381,932...65,381,997
JBrowse link
G Mir140 microRNA 140 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr 8:108,277,876...108,277,945
Ensembl chr 8:108,277,876...108,277,945
JBrowse link
G Mir143 microRNA 143 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr18:61,782,267...61,782,329
Ensembl chr18:61,782,267...61,782,329
JBrowse link
G Mir146b microRNA 146b ISO CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr19:46,331,201...46,331,309
Ensembl chr19:46,331,201...46,331,309
JBrowse link
G Mir148a microRNA 148a ISO CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr 6:51,246,792...51,246,890
Ensembl chr 6:51,246,792...51,246,890
JBrowse link
G Mir151 microRNA 151 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr15:73,126,664...73,126,731
Ensembl chr15:73,126,664...73,126,731
JBrowse link
G Mir152 microRNA 152 ISO CTD Direct Evidence: marker/mechanism CTD PMID:32583487 NCBI chr11:96,741,219...96,741,291
Ensembl chr11:96,741,219...96,741,291
JBrowse link
G Mir192 microRNA 192 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr19:6,314,874...6,314,962
Ensembl chr19:6,314,874...6,314,962
JBrowse link
G Mir215 microRNA 215 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr 1:185,045,778...185,045,889
Ensembl chr 1:185,045,778...185,045,889
JBrowse link
G Mir23a microRNA 23a ISO CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr 8:84,935,147...84,935,221
Ensembl chr 8:84,935,147...84,935,221
JBrowse link
G Mir25 microRNA 25 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr 5:138,163,583...138,163,666
Ensembl chr 5:138,163,583...138,163,666
JBrowse link
G Mir26a-1 microRNA 26a-1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr 9:118,860,864...118,860,953
Ensembl chr 9:118,860,864...118,860,953
JBrowse link
G Mir30a microRNA 30a ISO CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr 1:23,311,350...23,311,420
Ensembl chr 1:23,311,350...23,311,420
JBrowse link
G Mir30d microRNA 30d ISO CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr15:68,213,057...68,213,138
Ensembl chr15:68,213,057...68,213,138
JBrowse link
G Mir486 microRNA 486 EXP CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:30682439 PMID:35279909 NCBI chr 8:23,632,571...23,632,698
Ensembl chr 8:23,632,571...23,632,698
JBrowse link
G Mir99a microRNA 99a ISO CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr16:77,395,824...77,395,888
Ensembl chr16:77,395,824...77,395,888
JBrowse link
G Mirlet7i microRNA let7i ISO CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr10:122,821,545...122,821,629
Ensembl chr10:122,821,545...122,821,629
JBrowse link
G Mpo myeloperoxidase ISO DNA:haplotye: :
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:20623750 PMID:22739978 PMID:19793022 RGD:6909168, RGD:6909185 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17387702 NCBI chr 4:148,123,534...148,144,019
Ensembl chr 4:148,123,534...148,144,008
JBrowse link
G Mtor mechanistic target of rapamycin kinase ISO RGD PMID:23022334 RGD:7245507 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140
JBrowse link
G Muc20 mucin 20 IEP RGD PMID:14565953 RGD:7364790 NCBI chr16:32,597,793...32,617,805
Ensembl chr16:32,597,793...32,617,805
JBrowse link
G Mug1 murinoglobulin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chr 6:121,815,455...121,866,016
Ensembl chr 6:121,815,500...121,866,016
JBrowse link
G Myc myelocytomatosis oncogene susceptibility IEP protein:decreased phosphorylation:kidney (mouse) RGD PMID:23228991 RGD:7207407 NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223
JBrowse link
G Ndufb8 NADH:ubiquinone oxidoreductase subunit B8 ISO RGD PMID:22160772 RGD:13801199 NCBI chr19:44,537,010...44,543,881
Ensembl chr19:44,537,011...44,543,879
JBrowse link
G Nes nestin ISO RGD PMID:24503548 RGD:11570523 NCBI chr 3:87,878,400...87,887,758
Ensembl chr 3:87,878,385...87,887,758
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:24958931 PMID:24291173 RGD:10412697 NCBI chr 2:75,505,857...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29286200 NCBI chr 3:135,290,416...135,397,728
Ensembl chr 3:135,290,416...135,397,308
JBrowse link
G Nos1 nitric oxide synthase 1, neuronal ISO RGD PMID:14531809 RGD:13825139 NCBI chr 5:118,004,904...118,096,905
Ensembl chr 5:117,919,097...118,096,905
JBrowse link
G Nos2 nitric oxide synthase 2, inducible ISO CTD Direct Evidence: marker/mechanism CTD PMID:9810145 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell ISO CTD Direct Evidence: marker/mechanism
in females;mRNA:increased expression:cortex of kidney (rat)
CTD
RGD
PMID:9788586 PMID:28947737 RGD:13450947 NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472
JBrowse link
G Nppa natriuretic peptide type A ISO mRNA:increased expression:kidney
CTD Direct Evidence: marker/mechanism|therapeutic
CTD
RGD
PMID:1825077 PMID:2948068 PMID:19298916 PMID:22209992 RGD:7247715 NCBI chr 4:148,085,179...148,086,531
Ensembl chr 4:148,085,179...148,086,536
JBrowse link
G Nppb natriuretic peptide type B ISO associated with lung diseases;protein:increased expression:serum:
mRNA:increased expression:kidney
associated with Myocardial Infarction;protein:increased expression:serum:
associated with Pneumonia;protein:increased expression:serum:
RGD PMID:23837838 PMID:22209992 PMID:23192919 PMID:23415693 RGD:7247620, RGD:7247715, RGD:7247624, RGD:7247622 NCBI chr 4:148,070,264...148,071,662
Ensembl chr 4:148,070,245...148,071,662
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:26723870 PMID:28230744 RGD:13440091 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
JBrowse link
G Ocln occludin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19766176 NCBI chr13:100,633,012...100,689,226
Ensembl chr13:100,633,015...100,689,226
JBrowse link
G Orm1 orosomucoid 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chr 4:63,262,793...63,266,400
Ensembl chr 4:63,262,797...63,266,400
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 IMP RGD PMID:21884784 RGD:5510015 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel ISO protein:altered localization RGD PMID:12089381 RGD:7175293 NCBI chr 5:104,599,379...104,653,685
Ensembl chr 5:104,607,316...104,653,685
JBrowse link
G Plat plasminogen activator, tissue ISO protein:increased expression:plasma (human) RGD PMID:9767551 RGD:11541071 NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860
JBrowse link
G Plg plasminogen ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chr17:12,597,496...12,638,271
Ensembl chr17:12,597,495...12,638,272
JBrowse link
G Pomc pro-opiomelanocortin-alpha ISO CTD Direct Evidence: therapeutic CTD PMID:17216604 NCBI chr12:4,004,945...4,010,643
Ensembl chr12:4,004,951...4,010,642
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma treatment ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD
PMID:20623750 PMID:24011919 PMID:24433871 PMID:17494862 RGD:8553020 NCBI chr 6:115,337,840...115,467,365
Ensembl chr 6:115,337,912...115,467,360
JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha IEP
IMP
associated with Endotoxemia; mRNA:decreased expression:kidney (mouse) RGD PMID:21881206 PMID:21881206 RGD:7242026, RGD:7242026 NCBI chr 5:51,611,591...52,273,337
Ensembl chr 5:51,611,592...51,725,068
JBrowse link
G Proc protein C treatment ISO RGD PMID:19092124 RGD:11250410 NCBI chr18:32,256,179...32,272,623
Ensembl chr18:32,256,179...32,272,623
JBrowse link
G Procr protein C receptor, endothelial treatment ISO associated with Sepsis RGD PMID:23807243 RGD:10755583 NCBI chr 2:155,592,159...155,597,398
Ensembl chr 2:155,593,037...155,597,391
JBrowse link
G Ptafr platelet-activating factor receptor treatment ISO associated with Endotoxemia RGD PMID:2538527 RGD:10043182 NCBI chr 4:132,291,378...132,309,994
Ensembl chr 4:132,291,378...132,309,994
JBrowse link
G Ptger4 prostaglandin E receptor 4 (subtype EP4) treatment ISO RGD PMID:16871242 RGD:10003092 NCBI chr15:5,262,880...5,273,668
Ensembl chr15:5,236,142...5,273,668
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:21893983 RGD:5508181 NCBI chr 1:149,975,782...149,983,985
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Rapgef3 Rap guanine nucleotide exchange factor (GEF) 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21745194 NCBI chr15:97,637,886...97,666,300
Ensembl chr15:97,642,651...97,665,853
JBrowse link
G Rb1 RB transcriptional corepressor 1 ISO associated with Sepsis;protein:increased phosphorylation:kidney RGD PMID:19428114 RGD:8547990 NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262
JBrowse link
G Ren1 renin 1 structural exacerbates ISO Associated with toxic shock syndrome;protein:increased expression:blood plasma (human) RGD PMID:30407370 RGD:125097506 NCBI chr 1:133,278,412...133,288,058
Ensembl chr 1:133,278,248...133,288,063
JBrowse link
G Scgb1a1 secretoglobin, family 1A, member 1 ISO associated with LPS induced endotoxemia RGD PMID:18824919 RGD:2313129 NCBI chr19:9,061,006...9,065,320
Ensembl chr19:9,061,000...9,065,322
JBrowse link
G Serpinc1 serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 ISO associated with heart failure; protein:decreased activity:plasma: RGD PMID:26108065 RGD:11354006 NCBI chr 1:160,806,153...160,830,113
Ensembl chr 1:160,806,155...160,833,433
JBrowse link
G Sirt1 sirtuin 1 severity ISO protein:increased expression:kidney (rat)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:21416250 PMID:21416250 RGD:10047111 NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483
JBrowse link
G Slc11a1 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20623750 NCBI chr 1:74,414,318...74,429,974
Ensembl chr 1:74,414,354...74,425,221
JBrowse link
G Slc22a1 solute carrier family 22 (organic cation transporter), member 1 treatment ISO RGD PMID:22414646 RGD:7243179 NCBI chr17:12,867,761...12,894,725
Ensembl chr17:12,867,756...12,894,716
JBrowse link
G Slc22a12 solute carrier family 22 (organic anion/cation transporter), member 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14655203 NCBI chr19:6,585,884...6,593,100
Ensembl chr19:6,585,875...6,593,062
JBrowse link
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 treatment
susceptibility
ISO DNA:SNP: :808G>T (rs316019) human
mRNA:decreased expression:kidney
RGD PMID:22414646 PMID:19625999 PMID:18612803 RGD:7243179, RGD:7243884, RGD:7243880 NCBI chr17:12,803,076...12,847,376
Ensembl chr17:12,803,019...12,847,375
JBrowse link
G Slc34a1 solute carrier family 34 (sodium phosphate), member 1 disease_progression IEP associated with Sepsis; protein:decreased expression:renal proximal tubule (mouse) RGD PMID:19729856 RGD:7242943 NCBI chr13:55,547,435...55,562,508
Ensembl chr13:55,546,000...55,563,405
JBrowse link
G Sod1 superoxide dismutase 1, soluble ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217
JBrowse link
G Spp1 secreted phosphoprotein 1 IEP
ISO
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:11274264 PMID:20623750 PMID:22863853 RGD:6903264 NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916
JBrowse link
G Tff3 trefoil factor 3, intestinal ISO CTD Direct Evidence: marker/mechanism CTD PMID:23052191 NCBI chr17:31,344,280...31,348,585
Ensembl chr17:31,344,280...31,348,620
JBrowse link
G Tgfa transforming growth factor alpha ISO mRNA:increased expression:kidney RGD PMID:11340354 RGD:10395241 NCBI chr 6:86,172,020...86,252,726
Ensembl chr 6:86,172,205...86,252,701
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10469268 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor I ISO CTD Direct Evidence: marker/mechanism CTD PMID:34677723 NCBI chr 4:47,353,222...47,414,926
Ensembl chr 4:47,353,222...47,414,931
JBrowse link
G Thbd thrombomodulin treatment ISO RGD PMID:19176699 PMID:17804460 RGD:5684994, RGD:5685010 NCBI chr 2:148,246,391...148,250,108
Ensembl chr 2:148,246,386...148,250,108
JBrowse link
G Tlr2 toll-like receptor 2 IMP
ISO
associated with Sepsis
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:29286200 PMID:22655058 RGD:7207898 NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074
JBrowse link
G Tlr4 toll-like receptor 4 treatment IMP
ISO
IEP
associated with Sepsis
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:29286200 PMID:22655058 PMID:16638912 PMID:22266601 RGD:7207898, RGD:7241084, RGD:6892690 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521
JBrowse link
G Tlr9 toll-like receptor 9 IMP associated with Sepsis RGD PMID:23548820 RGD:7245966 NCBI chr 9:106,099,797...106,104,075
Ensembl chr 9:106,099,797...106,104,082
JBrowse link
G Tnf tumor necrosis factor susceptibility IMP
ISO
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:16595132 PMID:18460982 PMID:20623750 PMID:21150875 RGD:7245548 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnfrsf12a tumor necrosis factor receptor superfamily, member 12a ISO CTD Direct Evidence: marker/mechanism CTD PMID:23052191 NCBI chr17:23,894,419...23,896,423
Ensembl chr17:23,894,419...23,896,442
JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a susceptibility ISO
IMP
associated with Acute Lung Injury
associated with Endotoxemia
associated with Shock, Septic;protein:increased expression:serum
RGD PMID:18074478 PMID:21150875 PMID:12023385 PMID:12500222 RGD:5128661, RGD:7245548, RGD:7245535, RGD:7245534 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447
JBrowse link
G Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b ISO
IMP
associated with Acute Lung Injury
associated with Shock, Septic;protein:increased expression:serum
RGD PMID:18074478 PMID:12500222 PMID:12865254 RGD:5128661, RGD:7245534, RGD:7245532 NCBI chr 4:144,938,938...144,973,453
Ensembl chr 4:144,940,033...144,973,440
JBrowse link
G Trf transferrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chr 9:103,086,075...103,107,485
Ensembl chr 9:103,081,200...103,107,643
JBrowse link
G Trp53 transformation related protein 53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20603111 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
G Ttr transthyretin ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chr18:20,797,266...20,807,383
Ensembl chr18:20,798,337...20,807,378
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:3864191 NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase 1 family, polypeptide A9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20623750 NCBI chr 1:87,998,501...88,147,724
Ensembl chr 1:87,998,522...88,146,719
JBrowse link
G Uox urate oxidase ISO CTD Direct Evidence: therapeutic CTD PMID:16313266 NCBI chr 3:146,302,904...146,337,238
Ensembl chr 3:146,276,181...146,338,060
JBrowse link
G Uts2r urotensin 2 receptor ISO RGD PMID:15146030 RGD:2306847 NCBI chr11:121,051,097...121,052,799
Ensembl chr11:121,051,097...121,052,799
JBrowse link
G Vegfa vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:20943766 PMID:22808199 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
JBrowse link
G Wnt4 wingless-type MMTV integration site family, member 4 ISO RGD PMID:12707392 RGD:727218 NCBI chr 4:137,004,946...137,026,812
Ensembl chr 4:137,004,800...137,027,037
JBrowse link
G Xdh xanthine dehydrogenase treatment ISO
IDA
associated with Reperfusion Injury RGD PMID:22571266 PMID:18539378 PMID:19628223 RGD:7247641, RGD:7247656, RGD:7247650 NCBI chr17:74,190,890...74,257,369
Ensembl chr17:74,190,890...74,257,191
JBrowse link
acute kidney tubular necrosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ak4 adenylate kinase 4 ISO protein:decreased expression:kidney (rat) RGD PMID:21152904 RGD:5134352 NCBI chr 4:101,273,675...101,324,968
Ensembl chr 4:101,276,474...101,324,192
JBrowse link
G Bmp7 bone morphogenetic protein 7 ISO associated with Kidney Reperfusion Injury;protein:increased expression:kidney RGD PMID:16284088 RGD:1601494 NCBI chr 2:172,709,805...172,782,114
Ensembl chr 2:172,709,805...172,782,114
JBrowse link
G Cct7 chaperonin containing Tcp1, subunit 7 (eta) ISO CTD Direct Evidence: marker/mechanism CTD PMID:31825490 NCBI chr 6:85,428,487...85,445,459
Ensembl chr 6:85,428,496...85,445,457
JBrowse link
G Ciita class II transactivator IEP mRNA:increased expression:kidney RGD PMID:9422398 RGD:7242901 NCBI chr16:10,297,877...10,348,928
Ensembl chr16:10,297,923...10,346,282
JBrowse link
G Fabp1 fatty acid binding protein 1, liver ISO CTD Direct Evidence: therapeutic CTD PMID:18368030 NCBI chr 6:71,176,863...71,182,018
Ensembl chr 6:71,176,811...71,182,007
JBrowse link
G Gsr glutathione reductase IMP
ISO
protein:decreased activity:renal cortex: RGD PMID:17078987 PMID:12885594 RGD:7257555, RGD:7257573 NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 ISO protein:increased expression:kidney tubule, urine: RGD PMID:12081583 RGD:7245970 NCBI chr11:46,630,644...46,670,405
Ensembl chr11:46,625,907...46,670,405
JBrowse link
G Nog noggin ISO associated with Kidney Reperfusion Injury RGD PMID:16284088 RGD:1601494 NCBI chr11:89,191,464...89,193,385
Ensembl chr11:89,191,464...89,193,158
JBrowse link
G Pomc pro-opiomelanocortin-alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:4358912 PMID:6254450 NCBI chr12:4,004,945...4,010,643
Ensembl chr12:4,004,951...4,010,642
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:19834340 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial ISO CTD Direct Evidence: therapeutic CTD PMID:19917352 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
JBrowse link
G Tek TEK receptor tyrosine kinase ISO associated with Kidney Reperfusion Injury RGD PMID:16284088 RGD:1601494 NCBI chr 4:94,627,322...94,763,213
Ensembl chr 4:94,627,526...94,763,213
JBrowse link
ARC syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vipas39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog ISO
IEA
CTD Direct Evidence: marker/mechanism
OMIM:208085 | OMIM:613404
CTD
MouseDO
PMID:20190753 NCBI chr12:87,285,647...87,313,426
Ensembl chr12:87,285,642...87,313,030
JBrowse link
G Vps33b vacuolar protein sorting 33B IEA
ISO
OMIM:208085 | OMIM:613404
ClinVar Annotator: match by term: Arthrogryposis with renal dysfunction and cholestasis syndrome
CTD Direct Evidence: marker/mechanism
MouseDO
ClinVar
CTD
PMID:25741868 PMID:28492532 NCBI chr 7:79,919,369...79,941,327
Ensembl chr 7:79,919,397...79,941,502
JBrowse link
arthrogryposis, renal dysfunction, and cholestasis 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbn1 fibrillin 1 ISO ClinVar Annotator: match by term: Arthrogryposis, renal dysfunction, and cholestasis 1 ClinVar PMID:25741868 NCBI chr 2:125,142,514...125,348,417
Ensembl chr 2:125,142,514...125,349,913
JBrowse link
G Vipas39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog ISO ClinVar Annotator: match by term: Arthrogryposis, renal dysfunction, and cholestasis 1 ClinVar PMID:25741868 PMID:31319225 NCBI chr12:87,285,647...87,313,426
Ensembl chr12:87,285,642...87,313,030
JBrowse link
G Vps33b vacuolar protein sorting 33B ISO ClinVar Annotator: match by term: Arthrogryposis, renal dysfunction, and cholestasis 1 OMIM
ClinVar
PMID:8151641 PMID:11668108 PMID:15052268 PMID:16896922 PMID:17994566 More... NCBI chr 7:79,919,369...79,941,327
Ensembl chr 7:79,919,397...79,941,502
JBrowse link
arthrogryposis, renal dysfunction, and cholestasis 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vipas39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog ISO ClinVar Annotator: match by term: Arthrogryposis, renal dysfunction, and cholestasis 2 OMIM
ClinVar
PMID:20190753 PMID:25741868 PMID:28492532 NCBI chr12:87,285,647...87,313,426
Ensembl chr12:87,285,642...87,313,030
JBrowse link
atypical hemolytic-uremic syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts13 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13 ISO protein:decreased activity:serum (human)
ClinVar Annotator: match by term: Atypical hemolytic-uremic syndrome
ClinVar
RGD
PMID:12753286 PMID:17187257 PMID:17627784 PMID:23715102 PMID:25741868 More... RGD:10449096 NCBI chr 2:26,863,363...26,899,638
Ensembl chr 2:26,863,428...26,899,640
JBrowse link
G Baat bile acid-Coenzyme A: amino acid N-acyltransferase ISO ClinVar Annotator: match by term: Hemolytic uremic syndrome, atypical, susceptibility to, 1 ClinVar NCBI chr 4:49,489,416...49,507,915
Ensembl chr 4:49,489,422...49,506,557
JBrowse link
G C2 complement component 2 (within H-2S) ISO ClinVar Annotator: match by term: AHUS, SUSCEPTIBILITY TO, 4 | ClinVar Annotator: match by term: Atypical hemolytic-uremic syndrome ClinVar PMID:2249879 PMID:6308626 PMID:8181962 PMID:16518403 PMID:16936732 More... NCBI chr17:35,081,578...35,101,076
Ensembl chr17:35,081,580...35,117,241
JBrowse link
G C3 complement component 3 susceptibility IGI
ISO
ClinVar Annotator: match by term: AHUS, SUSCEPTIBILITY TO, 5 | ClinVar Annotator: match by term: Atypical hemolytic-uremic syndrome | ClinVar Annotator: match by term: Familial Atypical Hemolytic-Uremic Syndrome
CTD Direct Evidence: marker/mechanism
DNA:missense mutations: :p.F603V, p.R1042L, p.I1157T (human)
ClinVar
CTD
OMIM
RGD
PMID:1976733 PMID:14639503 PMID:17634448 PMID:18325906 PMID:18796626 More... RGD:7364995, RGD:11040768 NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136
JBrowse link
G C3ar1 complement component 3a receptor 1 ISO ClinVar Annotator: match by term: Hemolytic uremic syndrome, atypical, susceptibility to, 1 ClinVar NCBI chr 6:122,824,099...122,833,116
Ensembl chr 6:122,824,097...122,833,120
JBrowse link
G Cd46 CD46 antigen, complement regulatory protein severity
susceptibility
ISO DNA:mutations:cds:multiple (human)
ClinVar Annotator: match by term: AHUS, SUSCEPTIBILITY TO, 2 | ClinVar Annotator: match by term: AHUS, SUSCEPTIBILITY TO, 4 | ClinVar Annotator: match by term: Atypical hemolytic-uremic syndrome | ClinVar Annotator: match by term: Familial Atypical Hemolytic-Uremic Syndrome | ClinVar Annotator: match by term: HEMOLYTIC UREMIC SYNDROME, ATYPICAL, SUSCEPTIBILITY TO, 2
ClinVar Annotator: match by term: AHUS, SUSCEPTIBILITY TO, 1 | ClinVar Annotator: match by term: AHUS, SUSCEPTIBILITY TO, 2 | ClinVar Annotator: match by term: AHUS, SUSCEPTIBILITY TO, 5 | ClinVar Annotator: match by term: Atypical hemolytic uremic syndrome | ClinVar Annotator: match by term: HEMOLYTIC UREMIC SYNDROME, ATYPICAL, SUSCEPTIBILITY TO, 2
CTD Direct Evidence: marker/mechanism
protein:increased expression:peripheral blood mononuclear cell (human)
DNA:snp:intron:c.IVS8+23T>G (rs2724374) (human)
DNA:missense mutations:cds:p.R69W, p.A304V (human)
ClinVar
OMIM
CTD
RGD
PMID:270646 PMID:3480783 PMID:9551389 PMID:10528197 PMID:14566051 More... RGD:11038684, RGD:11352810, RGD:11040768, RGD:11352768 NCBI chr 1:194,721,279...194,781,149
Ensembl chr 1:194,719,134...194,774,557
JBrowse link
G Cfb complement factor B susceptibility ISO DNA, protein:mutations:cds: c.858C>G, F286L, c.967A>G, K323E (human)
ClinVar Annotator: match by term: AHUS, SUSCEPTIBILITY TO, 4 | ClinVar Annotator: match by term: Atypical hemolytic-uremic syndrome
CTD Direct Evidence: marker/mechanism
DNA:nonsense mutations: :multiple
ClinVar
OMIM
CTD
RGD
PMID:2249879 PMID:6308626 PMID:7452889 PMID:8181962 PMID:16518403 More... RGD:7242707, RGD:11040768 NCBI chr17:35,075,350...35,081,492
Ensembl chr17:35,075,350...35,081,494
JBrowse link
G Cfh complement component factor h susceptibility ISO
IEA
DNA:missense mutation
ClinVar Annotator: match by term: AHUS, SUSCEPTIBILITY TO, 1 | ClinVar Annotator: match by term: AHUS, SUSCEPTIBILITY TO, 3 | ClinVar Annotator: match by term: Atypical hemolytic-uremic syndrome | ClinVar Annotator: match by term: Hemolytic uremic syndrome, atypical, susceptibility to, 1
CTD Direct Evidence: marker/mechanism
DNA:nonsense mutations, missense mutations, splice-site mutation: :multiple
DNA:SNPs,Haplotype::
ClinVar
MouseDO
OMIM
CTD
RGD
PMID:646435 PMID:8072530 PMID:9536098 PMID:9551389 PMID:9811382 More... RGD:1599886, RGD:11041172, RGD:11041162, RGD:11040768, RGD:7364995 NCBI chr 1:140,013,593...140,111,149
Ensembl chr 1:140,012,446...140,111,502
JBrowse link
G Cfhr1 complement factor H-related 1 susceptibility ISO DNA:deletion
ClinVar Annotator: match by term: Hemolytic uremic syndrome, atypical, susceptibility to | ClinVar Annotator: match by term: Hemolytic uremic syndrome, atypical, susceptibility to, 1
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
RGD
PMID:16998489 PMID:17367211 PMID:18006700 PMID:20843825 PMID:25741868 More... RGD:11041162 NCBI chr 1:139,474,802...139,487,960
Ensembl chr 1:139,474,791...139,488,010
JBrowse link
G Cfhr2 complement factor H-related 2 susceptibility ISO ClinVar Annotator: match by term: Hemolytic uremic syndrome, atypical, susceptibility to | ClinVar Annotator: match by term: Hemolytic uremic syndrome, atypical, susceptibility to, 1
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
PMID:16998489 PMID:17367211 PMID:18006700 PMID:20843825 NCBI chr 1:139,738,030...139,786,437
Ensembl chr 1:139,731,905...139,786,456
JBrowse link
G Cfi complement component factor i susceptibility ISO ClinVar Annotator: match by term: AHUS, SUSCEPTIBILITY TO, 3 | ClinVar Annotator: match by term: AHUS, SUSCEPTIBILITY TO, 5 | ClinVar Annotator: match by term: Atypical hemolytic-uremic syndrome
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
RGD
PMID:9536098 PMID:15173250 PMID:16621965 PMID:17576681 PMID:18557729 More... RGD:6906889 NCBI chr 3:129,630,376...129,668,981
Ensembl chr 3:129,629,533...129,668,981
JBrowse link
G Col4a5 collagen, type IV, alpha 5 ISO ClinVar Annotator: match by term: Atypical hemolytic-uremic syndrome ClinVar PMID:7599631 PMID:7695699 PMID:8218237 PMID:8651296 PMID:8940267 More... NCBI chr  X:140,258,367...140,472,232
Ensembl chr  X:140,258,381...140,472,230
JBrowse link
G Dgke diacylglycerol kinase, epsilon ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Atypical hemolytic-uremic syndrome | ClinVar Annotator: match by term: Hemolytic uremic syndrome, atypical, susceptibility to, 1 | ClinVar Annotator: match by term: Hemolytic uremic syndrome, atypical, susceptibility to, 7
CTD
ClinVar
PMID:23542698 PMID:24511134 PMID:24747643 PMID:25741868 PMID:28492532 More... NCBI chr11:88,926,005...88,951,644
Ensembl chr11:88,926,005...88,957,676
JBrowse link
G Mmachc methylmalonic aciduria cblC type, with homocystinuria ISO ClinVar Annotator: match by term: Atypical hemolytic-uremic syndrome ClinVar PMID:16311595 PMID:16714133 PMID:17768669 PMID:17853453 PMID:18164228 More... NCBI chr 4:116,559,631...116,565,582
Ensembl chr 4:116,559,476...116,565,603
JBrowse link
G Plg plasminogen ISO ClinVar Annotator: match by term: Atypical hemolytic-uremic syndrome ClinVar NCBI chr17:12,597,496...12,638,271
Ensembl chr17:12,597,495...12,638,272
JBrowse link
G Smarcal1 SWI/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 ISO ClinVar Annotator: match by term: AHUS, SUSCEPTIBILITY TO, 4 | ClinVar Annotator: match by term: Atypical hemolytic-uremic syndrome ClinVar PMID:28492532 NCBI chr 1:72,575,593...72,675,949
Ensembl chr 1:72,622,410...72,672,293
JBrowse link
G Thbd thrombomodulin severity
susceptibility
no_association
ISO ClinVar Annotator: match by term: AHUS, SUSCEPTIBILITY TO, 6 | ClinVar Annotator: match by term: Atypical hemolytic-uremic syndrome
ClinVar Annotator: match by term: AHUS, SUSCEPTIBILITY TO, 6 | ClinVar Annotator: match by term: Atypical hemolytic uremic syndrome
CTD Direct Evidence: marker/mechanism
DNA:SNPs:5' utr, 3' utr:multiple
DNA:missense mutations:CDS:multiple
ClinVar
OMIM
CTD
RGD
PMID:7811989 PMID:9157575 PMID:9236408 PMID:10460600 PMID:11245641 More... RGD:11038684, RGD:11038691, RGD:11038691 NCBI chr 2:148,246,391...148,250,108
Ensembl chr 2:148,246,386...148,250,108
JBrowse link
Autosomal Dominant Tubulointerstitial Kidney Disease 4 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC107604629 Ren1 promoter and enhancer region ISO ClinVar Annotator: match by term: EARLY-ONSET HYPERURICEMIA, ANEMIA, AND PROGRESSIVE KIDNEY FAILURE | ClinVar Annotator: match by term: TUBULOINTERSTITIAL KIDNEY DISEASE, AUTOSOMAL DOMINANT, 4 ClinVar PMID:19664745 PMID:25741868 PMID:28492532 PMID:32750457 PMID:33532864 NCBI chr 1:133,273,725...133,278,434 JBrowse link
G Ren1 renin 1 structural ISO ClinVar Annotator: match by term: EARLY-ONSET HYPERURICEMIA, ANEMIA, AND PROGRESSIVE KIDNEY FAILURE | ClinVar Annotator: match by term: TUBULOINTERSTITIAL KIDNEY DISEASE, AUTOSOMAL DOMINANT, 4 OMIM
ClinVar
PMID:16116425 PMID:19664745 PMID:25741868 PMID:28492532 PMID:32750457 More... NCBI chr 1:133,278,412...133,288,058
Ensembl chr 1:133,278,248...133,288,063
JBrowse link
Azotemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gh growth hormone ISO CTD Direct Evidence: marker/mechanism CTD PMID:14728886 NCBI chr11:106,191,087...106,194,529
Ensembl chr11:106,191,097...106,192,691
JBrowse link
G Ren1 renin 1 structural ISO CTD Direct Evidence: marker/mechanism CTD PMID:6338847 NCBI chr 1:133,278,412...133,288,058
Ensembl chr 1:133,278,248...133,288,063
JBrowse link
Cardio-Renal Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Havcr1 hepatitis A virus cellular receptor 1 susceptibility ISO protein:increased expression:kidney tubule: RGD PMID:23220287 PMID:22367506 RGD:7245477, RGD:7245950 NCBI chr11:46,630,644...46,670,405
Ensembl chr11:46,625,907...46,670,405
JBrowse link
G Mir21a microRNA 21a ameliorates ISO RGD PMID:28760335 RGD:41410821 NCBI chr11:86,474,893...86,474,984
Ensembl chr11:86,474,893...86,474,984
JBrowse link
Chronic Allograft Nephropathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aco1 aconitase 1 ISO RGD PMID:20176611 RGD:11541086 NCBI chr 4:40,143,265...40,199,009
Ensembl chr 4:40,143,081...40,198,338
JBrowse link
G Alb albumin disease_progression ISO RGD PMID:24370342 RGD:11035281 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461
JBrowse link
G Ccl3 chemokine (C-C motif) ligand 3 ISO RGD PMID:17298994 RGD:7241819 NCBI chr11:83,538,669...83,540,204
Ensembl chr11:83,538,670...83,540,181
JBrowse link
G Ccn2 cellular communication network factor 2 disease_progression ISO mRNA, protein:increased expression:kidney (rat) RGD PMID:19921985 RGD:150517553 NCBI chr10:24,471,340...24,474,581
Ensembl chr10:24,471,340...24,474,581
JBrowse link
G Clu clusterin treatment ISO RGD PMID:22494435 RGD:9068431 NCBI chr14:66,205,932...66,218,997
Ensembl chr14:66,205,932...66,218,996
JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO RGD PMID:22845765 RGD:7241226 NCBI chr 9:7,445,822...7,455,975
Ensembl chr 9:7,445,822...7,455,975
JBrowse link
G Mmp7 matrix metallopeptidase 7 treatment ISO RGD PMID:18209025 RGD:9685339 NCBI chr 9:7,692,091...7,699,586
Ensembl chr 9:7,692,091...7,699,586
JBrowse link
G Pdgfa platelet derived growth factor, alpha ISO RGD PMID:11889420 RGD:11080974 NCBI chr 5:138,961,769...138,986,336
Ensembl chr 5:138,961,769...138,983,125
JBrowse link
G Pdgfb platelet derived growth factor, B polypeptide ISO mRNA:increased expression:kidney: RGD PMID:15785371 PMID:11889420 RGD:10449491, RGD:11080974 NCBI chr15:79,880,066...79,899,178
Ensembl chr15:79,880,075...79,899,178
JBrowse link
G Pdgfra platelet derived growth factor receptor, alpha polypeptide ISO RGD PMID:11889420 RGD:11080974 NCBI chr 5:75,311,988...75,358,867
Ensembl chr 5:75,312,953...75,358,876
JBrowse link
G Pdgfrb platelet derived growth factor receptor, beta polypeptide ISO RGD PMID:11889420 RGD:11080974 NCBI chr18:61,178,194...61,218,139
Ensembl chr18:61,178,222...61,218,133
JBrowse link
G Plau plasminogen activator, urokinase ISO protein:increased secretion:T lymphocyte (human) RGD PMID:16387096 RGD:7241259 NCBI chr14:20,886,730...20,893,456
Ensembl chr14:20,886,728...20,893,453
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma ISO protein:increased expression:kidney: RGD PMID:16221712 RGD:13208600 NCBI chr 6:115,337,840...115,467,365
Ensembl chr 6:115,337,912...115,467,360
JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 treatment ISO protein:increased expression:kidney: RGD PMID:16221712 PMID:18192922 RGD:13208600, RGD:13208601 NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122
JBrowse link
chronic kidney disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn4 actinin alpha 4 ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 NCBI chr 7:28,592,673...28,661,799
Ensembl chr 7:28,592,673...28,661,765
JBrowse link
G Ager advanced glycosylation end product-specific receptor disease_progression
severity
susceptibility
ISO DNA:polymorphism:promoter:g.-374T>A (human)
DNA:polymorphisms:promoter, intron:g.-429T>C, g.2184A>G (human)
associated with Diabetes Mellitus, Type 2; DNA:polymorphism:promoter:g.-429T>C (human)
protein:increased expression:serum (human)
RGD PMID:23593165 PMID:20185929 PMID:20353610 PMID:21432860 PMID:21822023 RGD:7243185, RGD:7242570, RGD:7244142, RGD:7243958, RGD:7243867 NCBI chr17:34,816,545...34,819,911
Ensembl chr17:34,816,836...34,819,910
JBrowse link
G Agtr1a angiotensin II receptor, type 1a disease_progression ISO DNA:polymorphism: :1166A>C (human) RGD PMID:12089373 PMID:12832734 RGD:6903863, RGD:8548869 NCBI chr13:30,520,339...30,566,850
Ensembl chr13:30,520,424...30,566,850
JBrowse link
G Agtr2 angiotensin II receptor, type 2 ISO RGD PMID:12089373 RGD:6903863 NCBI chr  X:21,350,863...21,355,072
Ensembl chr  X:21,350,783...21,355,403
JBrowse link
G Akap12 A kinase (PRKA) anchor protein (gravin) 12 susceptibility ISO DNA:polymorphism: :rs756009(human) RGD PMID:19724895 RGD:14349027 NCBI chr10:4,216,329...4,309,471
Ensembl chr10:4,216,380...4,309,470
JBrowse link
G Anln anillin, actin binding protein ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 PMID:28492532 NCBI chr 9:22,242,510...22,302,132
Ensembl chr 9:22,243,308...22,300,484
JBrowse link
G Aoc3 amine oxidase, copper containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23154672 NCBI chr11:101,221,432...101,230,256
Ensembl chr11:101,221,431...101,232,764
JBrowse link
G Apoa1 apolipoprotein A-I ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 NCBI chr 9:46,139,928...46,141,767
Ensembl chr 9:46,139,878...46,141,764
JBrowse link
G Apoa4 apolipoprotein A-IV disease_progression ISO protein:increased expression:blood plasma (human) RGD PMID:21569504 RGD:5685637 NCBI chr 9:46,152,142...46,154,756
Ensembl chr 9:46,151,994...46,154,757
JBrowse link
G Apoc3 apolipoprotein C-III ISO protein:increased expression:plasma RGD PMID:21829457 PMID:21297177 RGD:7207207, RGD:7207209 NCBI chr 9:46,144,348...46,146,934
Ensembl chr 9:46,144,231...46,146,934
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor (GDI) alpha ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 NCBI chr11:120,468,925...120,472,450
Ensembl chr11:120,468,930...120,472,450
JBrowse link
G Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 NCBI chr 1:71,596,315...71,618,562
Ensembl chr 1:71,596,309...71,618,790
JBrowse link
G Axdnd1 axonemal dynein light chain domain containing 1 ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:8589695 PMID:10742096 PMID:11805166 PMID:15253708 PMID:15327385 More... NCBI chr 1:156,157,985...156,248,743
Ensembl chr 1:156,151,079...156,248,729
JBrowse link
G Cbr1 carbonyl reductase 1 ISO mRNA, protein:decreased expression:liver RGD PMID:25332430 RGD:11565077 NCBI chr16:93,404,725...93,407,237
Ensembl chr16:93,402,741...93,407,393
JBrowse link
G Cfh complement component factor h ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 NCBI chr 1:140,013,593...140,111,149
Ensembl chr 1:140,012,446...140,111,502
JBrowse link
G Cfhr1 complement factor H-related 1 ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 NCBI chr 1:139,474,802...139,487,960
Ensembl chr 1:139,474,791...139,488,010
JBrowse link
G Cfi complement component factor i ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 PMID:28492532 NCBI chr 3:129,630,376...129,668,981
Ensembl chr 3:129,629,533...129,668,981
JBrowse link
G Clu clusterin ISO associated with Obesity;protein:increased expression:urine RGD PMID:24325231 RGD:9068427 NCBI chr14:66,205,932...66,218,997
Ensembl chr14:66,205,932...66,218,996
JBrowse link
G Col4a1 collagen, type IV, alpha 1 ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 PMID:28492532 NCBI chr 8:11,248,423...11,362,889
Ensembl chr 8:11,248,423...11,362,826
JBrowse link
G Col4a3 collagen, type IV, alpha 3 ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:14871398 PMID:17216251 PMID:24033266 PMID:24854265 PMID:25741868 More... NCBI chr 1:82,564,642...82,699,780
Ensembl chr 1:82,564,642...82,699,780
JBrowse link
G Col4a4 collagen, type IV, alpha 4 ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:12325029 PMID:21196518 PMID:24052634 PMID:24854265 PMID:25307543 More... NCBI chr 1:82,426,140...82,564,570
Ensembl chr 1:82,426,144...82,564,570
JBrowse link
G Cpb2 carboxypeptidase B2 (plasma) ISO DNA:polymorphism:cds :p.A147T(rs3742264)(human) RGD PMID:19056482 RGD:7243119 NCBI chr14:75,479,727...75,520,995
Ensembl chr14:75,479,727...75,520,995
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 ISO protein:decreased expression:liver: RGD PMID:23045433 RGD:10400847 NCBI chr15:76,386,212...76,396,225
Ensembl chr15:76,386,215...76,396,153
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 ISO protein:decreased expression:liver: RGD PMID:23045433 RGD:10400847 NCBI chr 7:98,802,870...98,831,920
Ensembl chr 7:98,802,865...98,831,926
JBrowse link
G Dnm1l dynamin 1-like treatment ISO RGD PMID:27801955 RGD:12738369 NCBI chr16:16,130,092...16,176,902
Ensembl chr16:16,130,094...16,176,823
JBrowse link
G Dstyk dual serine/threonine and tyrosine protein kinase ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 PMID:28492532 NCBI chr 1:132,345,127...132,394,697
Ensembl chr 1:132,345,293...132,394,696
JBrowse link
G Ehhadh enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 PMID:28492532 NCBI chr16:21,580,035...21,606,589
Ensembl chr16:21,580,037...21,606,557
JBrowse link
G Etfb electron transferring flavoprotein, beta polypeptide ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 PMID:28492532 NCBI chr 7:43,093,496...43,107,224
Ensembl chr 7:43,093,507...43,107,224
JBrowse link
G Fgf21 fibroblast growth factor 21 ISO protein:increased expression:serum: RGD PMID:22494291 RGD:10401925 NCBI chr 7:45,263,314...45,264,914
Ensembl chr 7:45,263,310...45,264,914
JBrowse link
G Fgf23 fibroblast growth factor 23 ISO protein:increased expression:serum: RGD PMID:20016468 RGD:10044210 NCBI chr 6:127,049,865...127,059,259
Ensembl chr 6:127,049,865...127,058,371
JBrowse link
G Fis1 fission, mitochondrial 1 treatment ISO RGD PMID:27801955 RGD:12738369 NCBI chr 5:136,982,129...136,995,088
Ensembl chr 5:136,982,129...136,995,088
JBrowse link
G Fn1 fibronectin 1 ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 PMID:28166811 PMID:28492532 NCBI chr 1:71,624,632...71,692,439
Ensembl chr 1:71,624,679...71,692,359
JBrowse link
G Frem1 Fras1 related extracellular matrix protein 1 ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 NCBI chr 4:82,816,157...82,970,743
Ensembl chr 4:82,816,157...82,970,576
JBrowse link
G Ganab alpha glucosidase 2 alpha neutral subunit ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 PMID:28492532 NCBI chr19:8,875,421...8,894,106
Ensembl chr19:8,875,435...8,894,036
JBrowse link
G Gja1 gap junction protein, alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:32045570 NCBI chr10:56,253,297...56,266,519
Ensembl chr10:56,253,426...56,278,609
JBrowse link
G Gp1ba glycoprotein 1b, alpha polypeptide exacerbates ISO RGD PMID:11314805 RGD:42722629 NCBI chr11:70,529,928...70,534,812
Ensembl chr11:70,529,948...70,532,862
JBrowse link
G Gpx1 glutathione peroxidase 1 treatment ISO RGD PMID:15954914 RGD:11352759 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 ISO RGD PMID:22269876 RGD:7245952 NCBI chr11:46,630,644...46,670,405
Ensembl chr11:46,625,907...46,670,405
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase ISO mRNA, protein:increased expression:liver RGD PMID:12841361 RGD:1300058 NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444
JBrowse link
G Hp haptoglobin ISO protein:increased expression:serum RGD PMID:18569920 RGD:11041800 NCBI chr 8:110,301,760...110,305,804
Ensembl chr 8:110,301,760...110,305,804
JBrowse link
G Il19 interleukin 19 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24714768 NCBI chr 1:130,860,393...130,873,194
Ensembl chr 1:130,860,393...130,867,852
JBrowse link
G Il1b interleukin 1 beta ISO
IEP
associated with Periodontitis; DNA:SNP:intron:g.3954C>T (human)
mRNA:increased expression:kidney (mouse)
protein:decreased expression:serum (human)
RGD PMID:22795294 PMID:21975861 PMID:22398717 PMID:22613545 PMID:22728154 RGD:6906881, RGD:7175304, RGD:7175171, RGD:7175169, RGD:7175095 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il1rn interleukin 1 receptor antagonist susceptibility ISO protein:increased expression:plasma (human)
DNA:repeats:intron:IVS2+914_1000dup IL1RN*1 (human)
RGD PMID:23024164 PMID:22795294 RGD:6906880, RGD:6906881 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506
JBrowse link
G Inf2 inverted formin, FH2 and WH2 domain containing ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 PMID:28492532 NCBI chr12:112,555,121...112,581,991
Ensembl chr12:112,555,218...112,581,991
JBrowse link
G Insr insulin receptor ISO protein:decreased phosphorylation:aorta RGD PMID:22942179 RGD:7207055 NCBI chr 8:3,200,922...3,329,649
Ensembl chr 8:3,172,061...3,329,617
JBrowse link
G Kl klotho disease_progression
treatment
ISO
IEP
IMP
mRNA,protein:decreased expression:renal tubule, epithelial cell:
protein:decreased expression:urine:
protein:decreased expression:urine,plasma,kidney:
RGD PMID:11967236 PMID:21115613 PMID:21115613 PMID:21115613 PMID:11967236 RGD:70544, RGD:10403077, RGD:10403077, RGD:10403077, RGD:70544 NCBI chr 5:150,876,072...150,917,282
Ensembl chr 5:150,876,072...150,917,282
JBrowse link
G Klk1 kallikrein 1 susceptibility ISO associated with Vesico-Ureteral Reflux RGD PMID:15086490 RGD:1581752 NCBI chr 7:43,874,784...43,879,046
Ensembl chr 7:43,874,784...43,879,042
JBrowse link
G Lcn2 lipocalin 2 disease_progression ISO
IMP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:24714768 PMID:20921623 RGD:126781837 NCBI chr 2:32,274,649...32,277,751
Ensembl chr 2:32,274,645...32,278,264
JBrowse link
G Lepr leptin receptor ISO RGD PMID:32390513 PMID:27465994 RGD:34888223, RGD:12911217 NCBI chr 4:101,574,393...101,676,375
Ensembl chr 4:101,574,601...101,672,549
JBrowse link
G LOC107983946 Wt1 promoter region ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 NCBI chr 2:104,956,361...104,957,127 JBrowse link
G Mfn1 mitofusin 1 treatment ISO RGD PMID:27801955 RGD:12738369 NCBI chr 3:32,583,594...32,633,374
Ensembl chr 3:32,583,614...32,633,388
JBrowse link
G Mt2 metallothionein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27122239 NCBI chr 8:94,899,246...94,900,195
Ensembl chr 8:94,899,292...94,900,196
JBrowse link
G Mthfr methylenetetrahydrofolate reductase susceptibility ISO DNA:polymorphism:cds:g.677C>T (human) RGD PMID:23595572 RGD:7244284 NCBI chr 4:148,123,534...148,144,019
Ensembl chr 4:148,123,534...148,144,008
JBrowse link
G Myh9 myosin, heavy polypeptide 9, non-muscle no_association ISO RGD PMID:22956460 RGD:12798515 NCBI chr15:77,644,785...77,726,375
Ensembl chr15:77,644,787...77,726,375
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 treatment ISO RGD PMID:23174956 RGD:10412711 NCBI chr 2:75,505,857...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Ngf nerve growth factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:24244623 NCBI chr 3:102,377,235...102,428,329
Ensembl chr 3:102,377,235...102,428,329
JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell susceptibility
treatment
ISO mRNA:decreased expression:cortex of kidney (rat) RGD PMID:29018182 PMID:29247650 RGD:13450920, RGD:13504713 NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472
JBrowse link
G Nphs1 nephrosis 1, nephrin severity ISO mRNA:increased expression:urine (human) RGD PMID:30133147 RGD:38549368 NCBI chr 7:30,157,259...30,188,048
Ensembl chr 7:30,157,740...30,186,648
JBrowse link
G Nphs2 nephrosis 2, podocin ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:8589695 PMID:10742096 PMID:11729243 PMID:11805166 PMID:11854170 More... NCBI chr 1:156,138,105...156,155,605
Ensembl chr 1:156,138,297...156,155,605
JBrowse link
G Nppa natriuretic peptide type A disease_progression ISO protein:increased expression:plasma RGD PMID:19052536 RGD:7247723 NCBI chr 4:148,085,179...148,086,531
Ensembl chr 4:148,085,179...148,086,536
JBrowse link
G Nppb natriuretic peptide type B disease_progression ISO RGD PMID:23725445 RGD:7246908 NCBI chr 4:148,070,264...148,071,662
Ensembl chr 4:148,070,245...148,071,662
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 treatment ISO RGD PMID:22227174 RGD:10769366 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 disease_progression ISO RGD PMID:24722447 RGD:12910103 NCBI chr15:101,151,788...101,172,676
Ensembl chr15:101,152,150...101,172,676
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase treatment ISO RGD PMID:27801955 RGD:12738369 NCBI chr16:29,398,099...29,481,924
Ensembl chr16:29,398,152...29,473,702
JBrowse link
G Pask PAS domain containing serine/threonine kinase ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 NCBI chr 1:93,237,159...93,271,244
Ensembl chr 1:93,236,492...93,271,204
JBrowse link
G Pcsk2 proprotein convertase subtilisin/kexin type 2 ISO RGD PMID:18039782 RGD:6483556 NCBI chr 2:143,388,053...143,658,204
Ensembl chr 2:143,388,076...143,658,205
JBrowse link
G Pkd1 polycystin 1, transient receptor potential channel interacting ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 NCBI chr17:24,767,657...24,815,488
Ensembl chr17:24,768,808...24,815,482
JBrowse link
G Postn periostin, osteoblast specific factor ISO protein:increased secretion:urine:
protein:increased expression:kidney:
RGD PMID:22167593 PMID:22403621 RGD:10040972, RGD:10041032 NCBI chr 3:54,266,688...54,298,462
Ensembl chr 3:54,268,530...54,298,458
JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha IDA RGD PMID:22648295 RGD:7242023 NCBI chr 5:51,611,591...52,273,337
Ensembl chr 5:51,611,592...51,725,068
JBrowse link
G Pth parathyroid hormone severity
treatment
ISO
IDA
associated with Diabetes Mellitus, Type 2; protein:increased expression:serum (human)
protein:decreased expression:plasma (rat)
RGD PMID:23528898 PMID:22517117 PMID:21826734 PMID:23345625 PMID:23467111 RGD:7242412, RGD:7242949, RGD:7242935, RGD:7242572, RGD:7242418 NCBI chr 7:112,984,783...112,987,879
Ensembl chr 7:112,984,787...112,987,777
JBrowse link
G Retn resistin ISO CTD Direct Evidence: marker/mechanism CTD PMID:22421264 NCBI chr 8:3,705,770...3,709,818
Ensembl chr 8:3,705,770...3,710,110
JBrowse link
G Rnls renalase, FAD-dependent amine oxidase ISO protein, activity:decreased expression:plasma, heart, kidney: RGD PMID:18299506 RGD:7327164 NCBI chr19:33,115,140...33,369,695
Ensembl chr19:33,115,147...33,369,665
JBrowse link
G Shh sonic hedgehog ISO
IEP
mRNA, protein:increased expression:kidney RGD PMID:24744439 PMID:24744439 RGD:12859042, RGD:12859042 NCBI chr 5:28,661,838...28,672,099
Ensembl chr 5:28,661,813...28,672,254
JBrowse link
G Slc19a1 solute carrier family 19 (folate transporter), member 1 ISO mRNA:decreased expression:multiple (rat) RGD PMID:21149507 RGD:7327184 NCBI chr10:76,868,103...76,886,266
Ensembl chr10:76,868,075...76,896,836
JBrowse link
G Slc19a2 solute carrier family 19 (thiamine transporter), member 2 ISO mRNA:decreased expression:liver, heart (rat) RGD PMID:21149507 RGD:7327184 NCBI chr 1:164,076,615...164,092,954
Ensembl chr 1:164,076,615...164,092,954
JBrowse link
G Slc19a3 solute carrier family 19, member 3 ISO mRNA:decreased expression:liver, heart, jejunum (rat) RGD PMID:21149507 RGD:7327184 NCBI chr 1:82,990,242...83,016,541
Ensembl chr 1:82,990,244...83,016,169
JBrowse link
G Slc34a1 solute carrier family 34 (sodium phosphate), member 1 ISO mRNA:decreased expression:kidney (rat)
DNA:snp:intron:IVS9+122A>G rs6420094 (human)
RGD PMID:21826734 PMID:20383146 RGD:7242935, RGD:7243100 NCBI chr13:55,547,435...55,562,508
Ensembl chr13:55,546,000...55,563,405
JBrowse link
G Slc46a1 solute carrier family 46, member 1 ISO mRNA:decreased expression:liver, heart, jejunum (rat) RGD PMID:21149507 RGD:7327184 NCBI chr11:78,356,527...78,362,771
Ensembl chr11:78,356,523...78,362,885
JBrowse link
G Slc9a3r1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:18784102 PMID:25741868 PMID:28492532 NCBI chr11:115,054,138...115,072,009
Ensembl chr11:115,054,167...115,072,007
JBrowse link
G Tbx18 T-box18 ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 NCBI chr 9:87,584,853...87,613,313
Ensembl chr 9:87,584,853...87,613,313
JBrowse link
G Tert telomerase reverse transcriptase treatment ISO RGD PMID:23013219 RGD:11038770 NCBI chr13:73,775,030...73,797,962
Ensembl chr13:73,775,030...73,797,962
JBrowse link
G Tfcp2l1 transcription factor CP2-like 1 ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:33097957 NCBI chr 1:118,555,646...118,612,898
Ensembl chr 1:118,555,675...118,612,898
JBrowse link
G Tlr9 toll-like receptor 9 susceptibility ISS DNA:SNPs:promoter, exon:g.-1237T>C, g.1635G>A (rs5743836, rs352140) (human, Han Chinese) RGD PMID:21908957 RGD:7246887 NCBI chr 9:106,099,797...106,104,075
Ensembl chr 9:106,099,797...106,104,082
JBrowse link
G Ttc21b tetratricopeptide repeat domain 21B ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:24033266 PMID:25741868 PMID:28492532 NCBI chr 2:66,014,131...66,087,144
Ensembl chr 2:66,014,671...66,086,961
JBrowse link
G Umod uromodulin ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 NCBI chr 7:119,061,931...119,078,485
Ensembl chr 7:119,061,934...119,078,505
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 ISO protein:increased expression:kidney
protein:increased expression:serum:
RGD PMID:20820841 PMID:21111939 RGD:4145364, RGD:7241036 NCBI chr 3:115,903,669...115,923,337
Ensembl chr 3:115,903,598...115,923,337
JBrowse link
G Wnt9b wingless-type MMTV integration site family, member 9B ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:34145744 NCBI chr11:103,618,188...103,666,098
Ensembl chr11:103,618,190...103,640,647
JBrowse link
G Wt1 WT1 transcription factor ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 NCBI chr 2:104,956,874...105,003,959
Ensembl chr 2:104,956,874...105,003,961
JBrowse link
G Xdh xanthine dehydrogenase treatment ISO associated with Hypertension;DNA:SNP: :66292C>G (human) RGD PMID:22622455 PMID:18712049 RGD:7247640, RGD:7247654 NCBI chr17:74,190,890...74,257,369
Ensembl chr17:74,190,890...74,257,191
JBrowse link
G Zfp423 zinc finger protein 423 ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 PMID:28492532 NCBI chr 8:88,388,438...88,688,665
Ensembl chr 8:88,388,438...88,686,223
JBrowse link
Contrast-Induced Nephropathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp12 caspase 12 treatment ISO RGD PMID:27781957 RGD:13782262 NCBI chr 9:5,345,419...5,373,034
Ensembl chr 9:5,345,430...5,373,032
JBrowse link
G Casp3 caspase 3 treatment ISO RGD PMID:27781957 RGD:13782262 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Crp C-reactive protein, pentraxin-related ISO associated with coronary disease; RGD PMID:23102387 RGD:6909166 NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 treatment ISO RGD PMID:27781957 RGD:13782262 NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157
JBrowse link
G Ece1 endothelin converting enzyme 1 ISO mRNA,protein:increased expression:kidney medulla RGD PMID:18385664 RGD:7243946 NCBI chr 4:137,589,548...137,692,540
Ensembl chr 4:137,589,548...137,692,540
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 ISO protein:increased expression:urine: RGD PMID:23335628 RGD:7245471 NCBI chr11:46,630,644...46,670,405
Ensembl chr11:46,625,907...46,670,405
JBrowse link
G Hspa5 heat shock protein 5 treatment ISO RGD PMID:27781957 RGD:13782262 NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559
JBrowse link
G Il1b interleukin 1 beta ISO associated with Diabetes Mellitus, Experimental RGD PMID:22094062 RGD:7175334 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Lcn2 lipocalin 2 ISO protein:increased expression:urine:
associated with Diabetes Mellitus, Experimental; protein:increased expression:urine
RGD PMID:23335628 PMID:23085980 RGD:7245471, RGD:7245484 NCBI chr 2:32,274,649...32,277,751
Ensembl chr 2:32,274,645...32,278,264
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 treatment ISO RGD PMID:27781957 RGD:13782262 NCBI chr14:33,099,855...33,169,215
Ensembl chr14:33,099,855...33,169,115
JBrowse link
G Mir188 microRNA 188 ISO RNA:increased expression:plasma
RNA:increased expression:plasma, kidney
RGD PMID:27528406 PMID:27528406 RGD:35673289, RGD:35673289 NCBI chr  X:7,114,228...7,114,295
Ensembl chr  X:7,114,228...7,114,295
JBrowse link
G Mir30a microRNA 30a ISO RNA:increased expression:plasma RGD PMID:27528406 PMID:27528406 RGD:35673289, RGD:35673289 NCBI chr 1:23,311,350...23,311,420
Ensembl chr 1:23,311,350...23,311,420
JBrowse link
G Mir30e microRNA 30e ISO RNA:increased expression:plasma RGD PMID:27528406 PMID:27528406 RGD:35673289, RGD:35673289 NCBI chr 4:120,629,803...120,629,894
Ensembl chr 4:120,629,803...120,629,894
JBrowse link
G Mpo myeloperoxidase ISO RGD PMID:20722568 RGD:6909183 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
JBrowse link
G Nppa natriuretic peptide type A ISO RGD PMID:19298916 RGD:7247719 NCBI chr 4:148,085,179...148,086,531
Ensembl chr 4:148,085,179...148,086,536
JBrowse link
G Nppb natriuretic peptide type B ISO associated with Heart Failure RGD PMID:20438292 RGD:7248591 NCBI chr 4:148,070,264...148,071,662
Ensembl chr 4:148,070,245...148,071,662
JBrowse link
Diarrhea prodrome + Hemolytic-Uremic Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gp1ba glycoprotein 1b, alpha polypeptide ISO associated with Escherichia Coli Infections;DNA:SNP:exon: (rs121908064) (human) RGD PMID:29216383 RGD:42722620 NCBI chr11:70,529,928...70,534,812
Ensembl chr11:70,529,948...70,532,862
JBrowse link
end stage renal disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP-binding cassette, sub-family A (ABC1), member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19878707 NCBI chr 4:53,030,789...53,159,988
Ensembl chr 4:53,030,787...53,159,895
JBrowse link
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A ISO RGD PMID:17135344 RGD:2301067 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
JBrowse link
G Abcb1b ATP-binding cassette, sub-family B (MDR/TAP), member 1B ISO RGD PMID:17135344 RGD:2301067 NCBI chr 5:8,848,147...8,916,314
Ensembl chr 5:8,848,147...8,916,315
JBrowse link
G Abcc2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 ISO RGD PMID:17135344 RGD:2301067 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179
JBrowse link
G Abcc3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 ISO protein:decreased expression:intestine RGD PMID:17135344 RGD:2301067 NCBI chr11:94,234,121...94,283,843
Ensembl chr11:94,234,121...94,283,823
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19878707 NCBI chr17:31,276,668...31,336,958
Ensembl chr17:31,276,649...31,336,962
JBrowse link
G Acat1 acetyl-Coenzyme A acetyltransferase 1 ISO protein:increased expression:kidney (rat)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:19878707 PMID:19878707 RGD:2326081 NCBI chr 9:53,491,822...53,521,650
Ensembl chr 9:53,491,822...53,521,682
JBrowse link
G Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 treatment
susceptibility
ISO CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Type 2;DNA:deletion:intron:IVS16+1464-1751del (human)
associated with Vesico-Ureteral Reflux;DNA:deletion
CTD
RGD
PMID:7593601 PMID:10099885 PMID:15118671 PMID:14586729 PMID:16385653 More... RGD:1331525, RGD:12879398, RGD:8142355, RGD:6903283 NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO protein:increased expression:serum, urine
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:19539174 PMID:24028144 RGD:8695941 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778
JBrowse link
G Adipor1 adiponectin receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:19539174 PMID:24028144 RGD:8695941 NCBI chr 1:134,343,116...134,361,089
Ensembl chr 1:134,343,116...134,361,089
JBrowse link
G Adipor2 adiponectin receptor 2 ISO RGD PMID:24028144 RGD:8695941 NCBI chr 6:119,330,111...119,394,489
Ensembl chr 6:119,330,111...119,394,665
JBrowse link
G Adrb2 adrenergic receptor, beta 2 ISO RGD PMID:9730702 RGD:7175286 NCBI chr18:62,310,784...62,313,052
Ensembl chr18:62,310,887...62,313,030
JBrowse link
G Ager advanced glycosylation end product-specific receptor ISO protein:increased expression:serum (human) RGD PMID:21822023 RGD:7243867 NCBI chr17:34,816,545...34,819,911
Ensembl chr17:34,816,836...34,819,910
JBrowse link
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) ISO GAD PMID:15118671 RGD:1331525 NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445
JBrowse link
G Agtr2 angiotensin II receptor, type 2 ISO
IMP
associated with Vesico-Ureteral Reflux;DNA:SNP: :-1332A>G (human) RGD PMID:20149750 PMID:19212419 RGD:6903283, RGD:6903843 NCBI chr  X:21,350,863...21,355,072
Ensembl chr  X:21,350,783...21,355,403
JBrowse link
G Alb albumin disease_progression ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:11938814 PMID:11849406 RGD:11036089 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461
JBrowse link
G Apoa1 apolipoprotein A-I treatment ISO
IDA
protein:decreased expression:blood
protein:increased expression, increased glycation:plasma
associated with Hyperlipidemias
RGD PMID:22515595 PMID:18079481 PMID:20488818 RGD:7241208, RGD:7241576, RGD:7241571 NCBI chr 9:46,139,928...46,141,767
Ensembl chr 9:46,139,878...46,141,764
JBrowse link
G Apoc2 apolipoprotein C2 ISO associated with Diabetes Mellitus, Insulin-Dependent RGD PMID:8139482 RGD:2313968 NCBI chr 7:19,405,504...19,411,866
Ensembl chr 7:19,405,504...19,411,866
JBrowse link
G Apoc3 apolipoprotein C-III ISO associated with Diabetes Mellitus, Insulin-Dependent
protein:increased expression: :
RGD PMID:8139482 PMID:10822722 RGD:2313968, RGD:7207212 NCBI chr 9:46,144,348...46,146,934
Ensembl chr 9:46,144,231...46,146,934
JBrowse link
G Apoe apolipoprotein E IMP
ISO
protein:increased expression:serum (human) RGD PMID:21705678 PMID:21332332 RGD:6903287, RGD:6904217 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113
JBrowse link
G Arg2 arginase type II ISO protein:decreased activity:kidney (rat) RGD PMID:16809898 RGD:4110828 NCBI chr12:79,177,562...79,203,075
Ensembl chr12:79,177,551...79,203,075
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 treatment ISO RGD PMID:20424483 RGD:11522730 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bdkrb1 bradykinin receptor, beta 1 resistance
no_association
ISO DNA: SNP: G-699-->C
DNA: SNP: G(-699)C
RGD PMID:9555662 PMID:10604543 PMID:10809796 RGD:7241560, RGD:7241582, RGD:7241561 NCBI chr12:105,570,350...105,571,770
Ensembl chr12:105,569,344...105,571,687
JBrowse link
G Becn1 beclin 1, autophagy related ISO protein:increased expression:kidney RGD PMID:24090408 RGD:11561926 NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112
JBrowse link
G Bglap bone gamma carboxyglutamate protein ISO protein:increased expression:serum RGD PMID:20845051 PMID:17365904 RGD:7207235, RGD:7207409 NCBI chr 3:88,290,802...88,291,773
Ensembl chr 3:88,290,808...88,291,771
JBrowse link
G Bnip3 BCL2/adenovirus E1B interacting protein 3 ISO protein:increased expression:kidney RGD PMID:24090408 RGD:11561926 NCBI chr 7:138,492,565...138,511,235
Ensembl chr 7:138,492,565...138,511,248
JBrowse link
G C6 complement component 6 severity ISO RGD PMID:11912252 RGD:1600675 NCBI chr15:4,756,550...4,833,527
Ensembl chr15:4,756,657...4,844,449
JBrowse link
G Casr calcium-sensing receptor ISO protein:decreased expression:epigastric artery (human) RGD PMID:17537980 RGD:7205455 NCBI chr16:36,310,947...36,382,605
Ensembl chr16:36,314,058...36,382,503
JBrowse link
G Cat catalase ISO protein: decreased expression :kidney
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:16518626 PMID:19420110 PMID:20007347 RGD:6892947 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Cbr1 carbonyl reductase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26282591 NCBI chr16:93,404,725...93,407,237
Ensembl chr16:93,402,741...93,407,393
JBrowse link
G Ccl2 chemokine (C-C motif) ligand 2 susceptibility
treatment
ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism:promoter:-2518A>G (human)
CTD Direct Evidence: marker/mechanism
protein:increased expression:renal proximal tubule (rat)
CTD
RGD
PMID:19420110 PMID:19539174 PMID:17982227 PMID:18797164 PMID:12080327 RGD:2306990, RGD:2307007, RGD:8549739 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Ccl3 chemokine (C-C motif) ligand 3 ISO RGD PMID:22613545 RGD:7175169 NCBI chr11:83,538,669...83,540,204
Ensembl chr11:83,538,670...83,540,181
JBrowse link
G Ccl5 chemokine (C-C motif) ligand 5 ISO mRNA:increased expression:kidney cortex (rat) RGD PMID:19535570 RGD:4889989 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344
JBrowse link
G Ccr1 chemokine (C-C motif) receptor 1 IMP associated with Candidiasis, Invasive; RGD PMID:22916017 RGD:7241817 NCBI chr 9:123,762,163...123,768,729
Ensembl chr 9:123,762,161...123,768,729
JBrowse link
G Ccr5 chemokine (C-C motif) receptor 5 ISO mRNA:increased expression:kidney cortex (rat) RGD PMID:19535570 RGD:4889989 NCBI chr 9:123,921,557...123,934,153
Ensembl chr 9:123,921,580...123,947,736
JBrowse link
G Cd2ap CD2-associated protein IEA MouseDO NCBI chr17:43,059,857...43,187,595
Ensembl chr17:43,103,842...43,187,556
JBrowse link
G Cd40 CD40 antigen treatment
severity
ISO protein:increased expression:plasma RGD PMID:12941150 PMID:20846521 RGD:7248709, RGD:7248723 NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868
JBrowse link
G Cd40lg CD40 ligand ISO protein:increased expression:plasma RGD PMID:19019166 RGD:7248427 NCBI chr  X:56,257,503...56,269,402
Ensembl chr  X:56,257,503...56,269,402
JBrowse link
G Cd68 CD68 antigen ISO CTD Direct Evidence: marker/mechanism CTD PMID:19539174 NCBI chr11:69,555,039...69,556,996
Ensembl chr11:69,555,039...69,556,979
JBrowse link
G Cfb complement factor B severity IMP
ISO
RGD PMID:17522263 PMID:1837062 RGD:7242704, RGD:7242753 NCBI chr17:35,075,350...35,081,492
Ensembl chr17:35,075,350...35,081,494
JBrowse link
G Chga chromogranin A ISO protein:increased expression:serum
associated with Hypertension;DNA:polymorphisms, haplotypes:promoter, 3' utr:multiple
RGD PMID:20730520 PMID:18235090 RGD:6906898, RGD:6906903 NCBI chr12:102,521,200...102,531,286
Ensembl chr12:102,521,228...102,531,287
JBrowse link
G Col1a1 collagen, type I, alpha 1 ISO RGD PMID:25782334 RGD:11041185 NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868
JBrowse link
G Col3a1 collagen, type III, alpha 1 ISO DNA:polymorphism: :p.I1205V (human) RGD PMID:19424605 RGD:7257553 NCBI chr 1:45,350,698...45,388,866
Ensembl chr 1:45,350,698...45,388,866
JBrowse link
G Col4a3 collagen, type IV, alpha 3 ISO RGD PMID:19357112 RGD:7242047 NCBI chr 1:82,564,642...82,699,780
Ensembl chr 1:82,564,642...82,699,780
JBrowse link
G Col4a4 collagen, type IV, alpha 4 ISO ClinVar Annotator: match by term: Stage 5 chronic kidney disease ClinVar
RGD
PMID:24033266 PMID:25741868 PMID:28492532 PMID:19357112 RGD:7242047 NCBI chr 1:82,426,140...82,564,570
Ensembl chr 1:82,426,144...82,564,570
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1a, liver ISO CTD Direct Evidence: marker/mechanism CTD PMID:19878707 NCBI chr19:3,372,328...3,435,735
Ensembl chr19:3,372,334...3,435,733
JBrowse link
G Crp C-reactive protein, pentraxin-related disease_progression ISO protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:19539174 PMID:22865783 RGD:6906886 NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598
JBrowse link
G Csf1 colony stimulating factor 1 (macrophage) ISO protein:increased expression:plasma RGD PMID:11340249 RGD:7257586 NCBI chr 3:107,648,364...107,668,048
Ensembl chr 3:107,648,364...107,667,785
JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 ISO associated with Wegener Granulomatosis;DNA:polymorphisms:promoter,exon::-318C>T, (AT)repeats (human) RGD PMID:15708894 RGD:7204725 NCBI chr 1:60,948,184...60,954,991
Ensembl chr 1:60,926,159...60,954,991
JBrowse link
G Cxcr1 chemokine (C-X-C motif) receptor 1 ISO RGD PMID:20649681 RGD:7207863 NCBI chr 1:74,230,944...74,233,867
Ensembl chr 1:74,230,944...74,233,790
JBrowse link
G Cxcr2 chemokine (C-X-C motif) receptor 2 ISO DNA:polymorphism: :1208C>T (human) RGD PMID:23615182 RGD:7257672 NCBI chr 1:74,193,153...74,200,405
Ensembl chr 1:74,193,148...74,200,405
JBrowse link
G Cyba cytochrome b-245, alpha polypeptide ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:19420110 PMID:19420110 RGD:2306994 NCBI chr 8:123,151,510...123,159,679
Ensembl chr 8:123,151,515...123,159,669
JBrowse link
G Cybb cytochrome b-245, beta polypeptide ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:19420110 PMID:15550752 RGD:1599682 NCBI chr  X:9,301,493...9,354,005
Ensembl chr  X:9,301,491...9,354,010
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 ISO DNA:polymorphisms:exon, 3' utr:3801T>C (rs4646903), p.I462V (rs1048943) (human)
mRNA, protein:decreased expression:intestine
RGD PMID:23619522 PMID:12039987 RGD:7257728, RGD:7296923 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15248218 NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049
JBrowse link
G Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 ISO DNA:polymorphisms: : RGD PMID:18769365 RGD:7243146 NCBI chr19:39,275,488...39,319,157
Ensembl chr19:39,257,849...39,319,157
JBrowse link
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15248218 NCBI chr19:39,378,000...39,451,547
Ensembl chr19:39,378,000...39,451,519
JBrowse link
G Cyp2c52-ps cytochrome P450, family 2, subfamily c, polypeptide 52, pseudogene ISO RGD PMID:8531418 PMID:11158222 RGD:6903939 RGD:6903940 NCBI chr19:38,965,106...38,992,071
Ensembl chr19:38,965,091...38,991,733
JBrowse link
G Cyp2c55 cytochrome P450, family 2, subfamily c, polypeptide 55 ISO RGD PMID:11158222 PMID:8531418 RGD:6903939, RGD:6903940 NCBI chr19:38,995,384...39,031,134
Ensembl chr19:38,995,463...39,031,137
JBrowse link
G Cyp2c66 cytochrome P450, family 2, subfamily c, polypeptide 66 ISO DNA:polymorphisms: : RGD PMID:18769365 RGD:7243146 NCBI chr19:39,102,342...39,175,200
Ensembl chr19:39,102,342...39,175,516
JBrowse link
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 ISO mRNA, protein:decreased expression:intestine RGD PMID:12039987 RGD:7296923 NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774
JBrowse link
G Ddc dopa decarboxylase ISO protein:altered activity:renal cortex (rat) RGD PMID:19167406 RGD:5128880 NCBI chr11:11,764,101...11,848,144
Ensembl chr11:11,764,101...11,848,144
JBrowse link
G Drd1 dopamine receptor D1 treatment ISO RGD PMID:18402547 RGD:7248448 NCBI chr13:54,205,202...54,209,677
Ensembl chr13:54,205,202...54,209,724
JBrowse link
G Drd2 dopamine receptor D2 ISO associated with Diabetes Mellitus, Non-Insulin Dependent; DNA:polymorphisms:5'utr, intron: -141delC, G>A (human) RGD PMID:18366720 RGD:2311602 NCBI chr 9:49,251,633...49,319,477
Ensembl chr 9:49,251,927...49,319,477
JBrowse link
G Edn1 endothelin 1 ISO mRNA:increased expression:kidney (rat) RGD PMID:8441230 RGD:4144849 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466
JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 ISO Associated with Type 2 diabetes RGD PMID:18184924 RGD:6906927 NCBI chr10:24,513,812...24,588,057
Ensembl chr10:24,513,812...24,588,057
JBrowse link
G Ephx2 epoxide hydrolase 2, cytoplasmic disease_progression IMP RGD PMID:20694143 RGD:5688726 NCBI chr14:66,321,821...66,361,971
Ensembl chr14:66,321,823...66,361,949
JBrowse link
G Epo erythropoietin ISO CTD Direct Evidence: therapeutic CTD PMID:16707910 NCBI chr 5:137,481,282...137,484,078
Ensembl chr 5:137,481,282...137,531,504
JBrowse link
G Epor erythropoietin receptor ISO protein:decreased expression:heart RGD PMID:27468524 RGD:11532749 NCBI chr 9:21,870,193...21,874,915
Ensembl chr 9:21,870,193...21,874,802
JBrowse link
G F2 coagulation factor II treatment ISO RGD PMID:22473220 RGD:7387323 NCBI chr 2:91,442,742...91,466,802
Ensembl chr 2:91,455,665...91,466,759
JBrowse link
G F5 coagulation factor V ISO DNA:mutation: :1691G>A(human) RGD PMID:19520684 RGD:6893522 NCBI chr 1:163,979,404...164,047,846
Ensembl chr 1:163,979,407...164,047,846
JBrowse link
G Fabp1 fatty acid binding protein 1, liver ISO CTD Direct Evidence: marker/mechanism CTD PMID:19878707 NCBI chr 6:71,176,863...71,182,018
Ensembl chr 6:71,176,811...71,182,007
JBrowse link
G Fabp2 fatty acid binding protein 2, intestinal ISO DNA:polymorphism:CDS:amino acid A54T, associated with Diabetes Mellitus, Type 2 (MeSH:D003924) RGD PMID:16249461 RGD:1578457 NCBI chr 3:122,688,721...122,693,155
Ensembl chr 3:122,688,721...122,693,155
JBrowse link
G Fasn fatty acid synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19878707 NCBI chr11:120,696,784...120,715,992
Ensembl chr11:120,696,672...120,715,373
JBrowse link
G Fcgr2b Fc receptor, IgG, low affinity IIb ISO RGD PMID:15266033 RGD:7240530 NCBI chr 1:170,788,127...170,803,691
Ensembl chr 1:170,786,186...170,804,116
JBrowse link
G Fgb fibrinogen beta chain treatment ISO associated with hypertension;DNA:polymorphism: :-455G>A (human) RGD PMID:19352213 RGD:7175505 NCBI chr 3:82,949,553...82,957,170
Ensembl chr 3:82,947,448...82,957,170
JBrowse link
G Fn1 fibronectin 1 ISO protein:decreased expression:plasma RGD PMID:6665521 RGD:7205701 NCBI chr 1:71,624,632...71,692,439
Ensembl chr 1:71,624,679...71,692,359
JBrowse link
G Gata3 GATA binding protein 3 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Stage 5 chronic kidney disease
CTD
ClinVar
PMID:25741868 PMID:26970513 NCBI chr 2:9,861,889...9,892,762
Ensembl chr 2:9,861,889...9,894,845
JBrowse link
G Gckr glucokinase regulatory protein ISO DNA: snp: rs1260326 RGD PMID:21980298 RGD:7242279 NCBI chr 5:31,454,594...31,484,646
Ensembl chr 5:31,454,787...31,484,658
JBrowse link
G Ghrl ghrelin ISO RGD PMID:18809976 RGD:7242553 NCBI chr 6:113,693,080...113,696,872
Ensembl chr 6:113,693,080...113,696,841
JBrowse link
G Glo1 glyoxalase 1 severity ISO DNA:SNP: :419C>A (human) RGD PMID:20185929 RGD:7242570 NCBI chr17:30,811,835...30,831,633
Ensembl chr17:30,803,910...30,845,845
JBrowse link
G Gsr glutathione reductase ISO protein:increased activity:blood:
protein:increased activity:lymphocyte:
RGD PMID:20181004 PMID:6463365 RGD:7257547, RGD:7257560 NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191
JBrowse link
G Gstm1 glutathione S-transferase, mu 1 ISO RGD PMID:24339523 RGD:14700960 NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289
JBrowse link
G Gstt1 glutathione S-transferase, theta 1 susceptibility ISO associated with Diabetes Mellitus;DNA:deletion RGD PMID:15492856 RGD:2306631 NCBI chr10:75,619,647...75,634,418
Ensembl chr10:75,619,647...75,634,418
JBrowse link
G Gtpbp4 GTP binding protein 4 ISO RGD PMID:11316846 RGD:632611 NCBI chr13:9,022,106...9,046,144
Ensembl chr13:9,016,367...9,046,119
JBrowse link
G Guca2b guanylate cyclase activator 2b (retina) ISO CTD Direct Evidence: marker/mechanism CTD PMID:15780094 NCBI chr 4:119,513,798...119,516,142
Ensembl chr 4:119,513,804...119,516,151
JBrowse link
G Hamp hepcidin antimicrobial peptide ISO mRNA:increased expression:liver
CTD Direct Evidence: marker/mechanism
protein:increased expression:plasma
CTD
RGD
PMID:16929540 PMID:20631677 PMID:19212416 RGD:11041611, RGD:11041622 NCBI chr 7:30,641,793...30,643,454
Ensembl chr 7:30,641,793...30,643,457
JBrowse link
G Hbegf heparin-binding EGF-like growth factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21937979 NCBI chr18:36,637,980...36,648,858
Ensembl chr18:36,637,980...36,648,858
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase ISO associated with Hypertension
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:19878707 PMID:21119529 RGD:5508686 NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444
JBrowse link
G Hmox1 heme oxygenase 1 ISO CTD Direct Evidence: therapeutic CTD PMID:22622455 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO protein:increased expression:kidney (rat) RGD PMID:20820841 RGD:4145364 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
JBrowse link
G Igf1 insulin-like growth factor 1 ISO CTD Direct Evidence: therapeutic CTD PMID:10198369 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904
JBrowse link
G Il1a interleukin 1 alpha no_association ISO DNA:SNP
DNA:SNPs, deletion, haplotypes:3' utr:multiple (human)
DNA:SNP, insertion/deletion:intron, 3' utr:rs1516792-3, rs16347-2 (human)
RGD PMID:20551628 PMID:12631337 PMID:12837270 RGD:6907070, RGD:6907106, RGD:6907105 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
JBrowse link
G Il1b interleukin 1 beta no_association ISO DNA:SNP
protein:increased expression:plasma (rat)
RGD PMID:20551628 PMID:20199183 PMID:22031851 RGD:6907070, RGD:7175346, RGD:7175302 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il1rn interleukin 1 receptor antagonist disease_progression
susceptibility
ISO DNA:repeats:intron:IVS2+914_1000dup IL1RN*2 (human)
DNA:repeats:intron:IVS2+914_1000dup IL1RN*1 (human)
protein:increased expression:serum (human)
DNA:polymorphism:exon:g.14709C>T rs315952 (human)
DNA:polymorphism:intron:IVS6+327A>G rs452204 (human)
RGD PMID:17224277 PMID:16766392 PMID:16556139 PMID:12837270 PMID:20551628 RGD:6907131, RGD:6907370, RGD:6907368, RGD:6907105, RGD:6907070 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506
JBrowse link
G Il20 interleukin 20 ISO protein:increased expression:multiple organs RGD PMID:18639518 RGD:5147394 NCBI chr 1:130,834,722...130,839,033
Ensembl chr 1:130,834,722...130,839,188
JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19539174 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Irs1 insulin receptor substrate 1 ISO protein:decreased tyrosine phosphorylation:aorta RGD PMID:22942179 RGD:7207055 NCBI chr 1:82,210,826...82,269,160
Ensembl chr 1:82,210,833...82,213,654
Ensembl chr 1:82,210,833...82,213,654
JBrowse link
G Itga8 integrin alpha 8 ISO associated with Polycystic Kidney, Autosomal Dominant;DNA:polymorphism: :-414T>C(human) RGD PMID:18277079 RGD:7257723 NCBI chr 2:12,111,443...12,306,796
Ensembl chr 2:12,111,443...12,306,733
JBrowse link
G Itgb3 integrin beta 3 ISO associated with Hypertension;DNA:polymorphism RGD PMID:19368146 RGD:6907396 NCBI chr11:104,498,826...104,561,302
Ensembl chr11:104,498,826...104,561,302
JBrowse link
G Keap1 kelch-like ECH-associated protein 1 ISO protein:increased expression:renal cortex, cytosol (rat) RGD PMID:20007347 RGD:6892947 NCBI chr 9:21,141,026...21,150,628
Ensembl chr 9:21,141,026...21,150,657
JBrowse link
G Kl klotho ISO mRNA,protein:decreased expression:kidney:
mRNA:decreased expression:kidney:
RGD PMID:11162628 PMID:9731228 RGD:10403042, RGD:10403067 NCBI chr 5:150,876,072...150,917,282
Ensembl chr 5:150,876,072...150,917,282
JBrowse link
G Klk1 kallikrein 1 ISO RGD PMID:11849458 RGD:1581753 NCBI chr 7:43,874,784...43,879,046
Ensembl chr 7:43,874,784...43,879,042
JBrowse link
G Lcat lecithin cholesterol acyltransferase ISO RGD PMID:15280162 RGD:1581769 NCBI chr 8:106,666,183...106,670,034
Ensembl chr 8:106,666,183...106,670,014
JBrowse link
G Lcn2 lipocalin 2 onset ISO protein:increased expression:urine: RGD PMID:22542304 RGD:7245503 NCBI chr 2:32,274,649...32,277,751
Ensembl chr 2:32,274,645...32,278,264
JBrowse link
G Lep leptin ISO protein:increased expression:serum (human) RGD PMID:9294834 RGD:10053636 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876
JBrowse link
G Lipc lipase, hepatic ISO protein, mRNA:decreased expression:hepatocytes, liver (rat) RGD PMID:8636395 RGD:2308788 NCBI chr 9:70,705,410...70,859,503
Ensembl chr 9:70,705,410...70,859,508
JBrowse link
G Lpin1 lipin 1 ISO mRNA:increased expression:skeletal muscle RGD PMID:14718385 RGD:1641826 NCBI chr12:16,585,670...16,697,020
Ensembl chr12:16,585,670...16,696,967
JBrowse link
G Lpl lipoprotein lipase ISO RGD PMID:22009636 RGD:6909179 NCBI chr 8:69,333,207...69,359,584
Ensembl chr 8:69,333,143...69,360,100
JBrowse link
G Lrp2 low density lipoprotein receptor-related protein 2 ISO mRNA:decreased expression:kidney RGD PMID:15266031 RGD:1641836 NCBI chr 2:69,254,679...69,416,373
Ensembl chr 2:69,254,684...69,416,409
JBrowse link
G Mbl2 mannose-binding lectin (protein C) 2 ISO associated with Lupus Erythematosus, Systemic;DNA:polymorphisms RGD PMID:16801331 RGD:6903261 NCBI chr19:30,210,306...30,217,087
Ensembl chr19:30,210,342...30,217,087
JBrowse link
G Mlxipl MLX interacting protein-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:19878707 NCBI chr 5:135,118,744...135,168,622
Ensembl chr 5:135,118,744...135,167,236
JBrowse link
G Mmp10 matrix metallopeptidase 10 ISO associated with Hypertension; protein:increased expression:plasma (human) RGD PMID:19886850 RGD:7207051 NCBI chr 9:7,502,343...7,510,243
Ensembl chr 9:7,502,353...7,510,241
JBrowse link
G Mmp1a matrix metallopeptidase 1a (interstitial collagenase) severity
no_association
ISO DNA:insertion, haplotype:promoter:g.-1607insG (human)
DNA:insertion:promoter:g.-1607insG (human)
RGD PMID:19221176 PMID:22401717 RGD:7207064, RGD:7206856 NCBI chr 9:7,464,141...7,476,870
Ensembl chr 9:7,464,141...7,476,857
JBrowse link
G Mmp1b matrix metallopeptidase 1b (interstitial collagenase) severity
no_association
ISO DNA:insertion, haplotype:promoter:g.-1607insG (human)
DNA:insertion:promoter:g.-1607insG (human)
RGD PMID:19221176 PMID:22401717 RGD:7206856 RGD:7207064 NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047
JBrowse link
G Mmp2 matrix metallopeptidase 2 ISO associated with Hypertension; protein:increased expression:plasma (human) RGD PMID:19886850 RGD:7207051 NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048
JBrowse link
G Mmp3 matrix metallopeptidase 3 severity ISO DNA:insertion, haplotype:promoter:g.-1613insA (human) RGD PMID:19221176 RGD:7207064 NCBI chr 9:7,445,822...7,455,975
Ensembl chr 9:7,445,822...7,455,975
JBrowse link
G Mpo myeloperoxidase disease_progression ISO RGD PMID:20638167 RGD:6909184 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
JBrowse link
G Msr1 macrophage scavenger receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19878707 NCBI chr 8:39,996,284...40,095,790
Ensembl chr 8:40,034,726...40,095,714
JBrowse link
G Mthfr methylenetetrahydrofolate reductase susceptibility
severity
no_association
ISO DNA:transition, transversion:cds:g.677C>T, g.1298A>C (human)
DNA:SNP: :677C>T(human)
DNA:transitions, transversion, haplotype:cds:g.677C>T, g.1298A>C, g.1793G>A (human)
associated with Diabetes Mellitus, Type 2; DNA:transition:cds:g.677C>T (human)
RGD PMID:19520684 PMID:25664255 PMID:17899317 PMID:14737040 PMID:19520069 RGD:6893522, RGD:14696732, RGD:6893579, RGD:6893524, RGD:6893523 NCBI chr 4:148,123,534...148,144,019
Ensembl chr 4:148,123,534...148,144,008
JBrowse link
G Mtor mechanistic target of rapamycin kinase treatment ISO RGD PMID:22427849 RGD:10040968 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140
JBrowse link
G Myh9 myosin, heavy polypeptide 9, non-muscle ISO associated with hypertension, glomerulosclerosis, focal segmental;DNA:SNPs: :rs4821480, rs2032487, rs4821481(human)
CTD Direct Evidence: marker/mechanism
associated with diabetes mellitus, type 2;DNA:SNPs: :
DNA:SNPs:multiple:
associated with hypertension;DNA:polymorphisms:multiple:
associated with diabetes mellitus,type 2;DNA:SNPs: :
CTD
RGD
PMID:18794854 PMID:18794856 PMID:18794854 PMID:21968013 PMID:20144966 More... RGD:6903237, RGD:6903256, RGD:6903243, RGD:6903239, RGD:6903238 NCBI chr15:77,644,785...77,726,375
Ensembl chr15:77,644,787...77,726,375
JBrowse link
G Nat2 N-acetyltransferase 2 (arylamine N-acetyltransferase) ISO mRNA,protein:decreased expression:liver: RGD PMID:20007296 RGD:11533637 NCBI chr 8:67,947,527...67,955,296
Ensembl chr 8:67,947,510...67,955,236
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19420110 NCBI chr 5:134,248,907...134,258,479
Ensembl chr 5:134,248,907...134,258,479
JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19420110 NCBI chr 3:135,290,416...135,397,728
Ensembl chr 3:135,290,416...135,397,308
JBrowse link
G Ngf nerve growth factor treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:24244623 PMID:19169037 RGD:7242783 NCBI chr 3:102,377,235...102,428,329
Ensembl chr 3:102,377,235...102,428,329
JBrowse link
G Nos1 nitric oxide synthase 1, neuronal treatment ISO protein:decreased expression:kidney cortex RGD PMID:17200156 PMID:23185775 RGD:1642147, RGD:7257669 NCBI chr 5:118,004,904...118,096,905
Ensembl chr 5:117,919,097...118,096,905
JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell susceptibility ISO protein:decreased expression:glomerulus
DNA:duplication, snp:intron, cds:g.IVS4?-?+27, p.E298D (human)
RGD PMID:18089446 PMID:12701818 RGD:2292109, RGD:7777097 NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472
JBrowse link
G Nox4 NADPH oxidase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19420110 NCBI chr 7:86,893,638...87,047,918
Ensembl chr 7:86,895,304...87,047,918
JBrowse link
G Nphs1 nephrosis 1, nephrin disease_progression ISO mRNA;increased expression:urine (rat) RGD PMID:19389856 RGD:38599006 NCBI chr 7:30,157,259...30,188,048
Ensembl chr 7:30,157,740...30,186,648
JBrowse link
G Nppb natriuretic peptide type B ISO protein:increased expression:plasma: RGD PMID:7606877 RGD:7246912 NCBI chr 4:148,070,264...148,071,662
Ensembl chr 4:148,070,245...148,071,662
JBrowse link
G Nppc natriuretic peptide type C ISO protein:increased expression:plasma
protein:increased expression:plasma (human)
RGD PMID:8117275 PMID:8743538 RGD:1642297, RGD:1580770 NCBI chr 1:86,594,015...86,598,295
Ensembl chr 1:86,594,013...86,598,293
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 ISO RGD PMID:18591458 RGD:7174716 NCBI chr18:39,543,598...39,652,485
Ensembl chr18:39,543,598...39,652,474
JBrowse link
G Olr1 oxidized low density lipoprotein (lectin-like) receptor 1 ISO mRNA, protein:increased expression:kidney (rat) RGD PMID:12661921 RGD:1580992 NCBI chr 6:129,456,113...129,484,312
Ensembl chr 6:129,462,207...129,484,128
JBrowse link
G Pax2 paired box 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16631587 NCBI chr19:44,735,040...44,826,708
Ensembl chr19:44,744,484...44,826,310
JBrowse link
G Pgf placental growth factor ISO RGD PMID:16543713 RGD:1642390 NCBI chr12:85,213,411...85,224,559
Ensembl chr12:85,213,409...85,224,564
JBrowse link
G Pkd1 polycystin 1, transient receptor potential channel interacting ISO ClinVar Annotator: match by term: Stage 5 chronic kidney disease ClinVar PMID:25741868 NCBI chr17:24,767,657...24,815,488
Ensembl chr17:24,768,808...24,815,482
JBrowse link
G Pla2g7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) ISO plasma:increased expression:plasma RGD PMID:16421163 RGD:7248787 NCBI chr17:43,878,885...43,923,093
Ensembl chr17:43,878,989...43,923,092
JBrowse link
G Plau plasminogen activator, urokinase treatment
severity
ISO protein:increased expression, increased activity:kidney (rat)
protein:increased expression:plasma (human)
RGD PMID:19926968 PMID:15506291 PMID:17869326 PMID:22683425 RGD:6483806, RGD:7241279, RGD:7241218, RGD:7241081 NCBI chr14:20,886,730...20,893,456
Ensembl chr14:20,886,728...20,893,453
JBrowse link
G Plaur plasminogen activator, urokinase receptor ISO RGD PMID:19926968 RGD:6483806 NCBI chr 7:24,161,857...24,175,393
Ensembl chr 7:24,161,909...24,175,393
JBrowse link
G Postn periostin, osteoblast specific factor ISO mRNA,protein:increased expression,increased secretion:kidney,urine: RGD PMID:22167593 RGD:10040972 NCBI chr 3:54,266,688...54,298,462
Ensembl chr 3:54,268,530...54,298,458
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:19878707 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma disease_progression ISO associated with Diabetes Mellitus, Insulin-Dependent;DNA:SNP: :p.P12A (human) RGD PMID:18467141 RGD:2301857 NCBI chr 6:115,337,840...115,467,365
Ensembl chr 6:115,337,912...115,467,360
JBrowse link
G Ptger4 prostaglandin E receptor 4 (subtype EP4) treatment ISO RGD PMID:16871242 RGD:10003092 NCBI chr15:5,262,880...5,273,668
Ensembl chr15:5,236,142...5,273,668
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19420110 NCBI chr 2:36,106,758...36,142,287
Ensembl chr 2:36,120,438...36,142,284
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19420110 NCBI chr 1:149,975,782...149,983,985
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Pth parathyroid hormone severity ISO protein:increased expression:serum (rat)
protein:increased expression:serum (human)
RGD PMID:23548814 PMID:23243213 RGD:7242564, RGD:7242692 NCBI chr 7:112,984,783...112,987,879
Ensembl chr 7:112,984,787...112,987,777
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) ISO protein:increased expression:kidney
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:19420110 PMID:18077597 RGD:2298859 NCBI chr19:5,687,569...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Retn resistin severity ISO protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:19539174 PMID:22421264 RGD:7207074 NCBI chr 8:3,705,770...3,709,818
Ensembl chr 8:3,705,770...3,710,110
JBrowse link
G Rnls renalase, FAD-dependent amine oxidase ISO protein:decreased expression:plasma:
ClinVar Annotator: match by term: Stage 5 chronic kidney disease
ClinVar
RGD
PMID:28492532 PMID:15841207 RGD:7327153 NCBI chr19:33,115,140...33,369,695
Ensembl chr19:33,115,147...33,369,665
JBrowse link
G Scarb1 scavenger receptor class B, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19878707 NCBI chr 5:125,354,151...125,418,158
Ensembl chr 5:125,354,151...125,418,158
JBrowse link
G Sell selectin, lymphocyte no_association ISO RGD PMID:22119815 RGD:7175303 NCBI chr 1:163,889,556...163,908,354
Ensembl chr 1:163,889,551...163,911,750
JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:19420110 PMID:26903149 RGD:11073683 NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122
JBrowse link
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 ISO protein:decreased expression:kidney, plasma membrane RGD PMID:23280877 PMID:12110012 RGD:7243177, RGD:7243883 NCBI chr17:12,803,076...12,847,376
Ensembl chr17:12,803,019...12,847,375
JBrowse link
G Slc34a1 solute carrier family 34 (sodium phosphate), member 1 ISO mRNA:decreased expression:renal cortex (rat) RGD PMID:15452708 RGD:7242930 NCBI chr13:55,547,435...55,562,508
Ensembl chr13:55,546,000...55,563,405
JBrowse link
G Slc9a5 solute carrier family 9 (sodium/hydrogen exchanger), member 5 resistance ISO DNA:polymorphism RGD PMID:10642288 RGD:1643221 NCBI chr 8:106,074,782...106,096,513
Ensembl chr 8:106,075,475...106,096,513
JBrowse link
G Soat2 sterol O-acyltransferase 2 ISO RGD PMID:12217884 RGD:625687 NCBI chr15:102,058,853...102,071,871
Ensembl chr15:102,058,961...102,071,904
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19878707 NCBI chr11:60,089,910...60,113,407
Ensembl chr11:60,089,915...60,113,407
JBrowse link
G Srebf2 sterol regulatory element binding factor 2 ISO mRNA, protein:increased expression:liver
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:19878707 PMID:16814791 RGD:2308825 NCBI chr15:82,031,470...82,089,580
Ensembl chr15:82,031,382...82,089,580
JBrowse link
G Tbx21 T-box 21 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26970513 NCBI chr11:96,988,833...97,006,157
Ensembl chr11:96,988,897...97,006,157
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO mRNA, protein:increased expression:kidney
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:19420110 PMID:10919844 RGD:7394838 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Thbd thrombomodulin IDA
ISO
protein:increased expression:plasma RGD PMID:22129968 PMID:21873362 RGD:5684979, RGD:5684981 NCBI chr 2:148,246,391...148,250,108
Ensembl chr 2:148,246,386...148,250,108
JBrowse link
G Tlr2 toll-like receptor 2 ISO RGD PMID:20729266 RGD:7240546 NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074
JBrowse link
G Tlr4 toll-like receptor 4 ISO RGD PMID:20729266 RGD:7240546 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521
JBrowse link
G Tnf tumor necrosis factor ISO associated with Diabetes Mellitus, Type 2;protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:19539174 PMID:22266663 RGD:7245510 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnfrsf11b tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) severity ISO RGD PMID:21479768 RGD:7205485 NCBI chr15:54,114,014...54,141,880
Ensembl chr15:54,114,015...54,141,880
JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a ISO associated with Diabetes Mellitus, Type 2;protein:increased expression:plasma RGD PMID:22266663 RGD:7245510 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447
JBrowse link
G Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b ISO associated with Diabetes Mellitus, Type 2;protein:increased expression:plasma RGD PMID:22266663 RGD:7245510 NCBI chr 4:144,938,938...144,973,453
Ensembl chr 4:144,940,033...144,973,440
JBrowse link
G Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) susceptibility ISO DNA:polymorphism: :-866G>A (human)
DNA:deletion
RGD PMID:19406964 PMID:18242170 RGD:7175298, RGD:7175299 NCBI chr 7:100,142,544...100,148,836
Ensembl chr 7:100,142,544...100,151,227
JBrowse link
G Vwf Von Willebrand factor disease_progression
treatment
ISO protein:increased oxidation:plasma RGD PMID:22189209 PMID:21378155 PMID:22091998 RGD:7205641, RGD:7205649, RGD:7205646 NCBI chr 6:125,529,911...125,663,642
Ensembl chr 6:125,523,737...125,663,642
JBrowse link
Frasier syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC107983946 Wt1 promoter region ISO ClinVar Annotator: match by term: Frasier syndrome ClinVar PMID:15266301 PMID:18559874 PMID:18591546 PMID:19171881 PMID:19221039 More... NCBI chr 2:104,956,361...104,957,127 JBrowse link
G Wt1 WT1 transcription factor ISO ClinVar Annotator: match by term: Frasier syndrome OMIM
ClinVar
PMID:1302008 PMID:1658787 PMID:7795587 PMID:8388765 PMID:9108089 More... NCBI chr 2:104,956,874...105,003,959
Ensembl chr 2:104,956,874...105,003,961
JBrowse link
hemolytic-uremic syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:6734075 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461
JBrowse link
G Ccl2 chemokine (C-C motif) ligand 2 ISO protein:increased expression:plasma (rat) RGD PMID:10201001 RGD:11528527 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Ccl3 chemokine (C-C motif) ligand 3 IMP RGD PMID:17220320 RGD:7241820 NCBI chr11:83,538,669...83,540,204
Ensembl chr11:83,538,670...83,540,181
JBrowse link
G Cd36 CD36 molecule ISO RGD PMID:16197457 RGD:6893534 NCBI chr 5:17,986,688...18,093,957
Ensembl chr 5:17,986,688...18,093,799
JBrowse link
G Cd46 CD46 antigen, complement regulatory protein susceptibility ISO DNA:frameshift mutation:cds:p.N233X3 (human)
DNA:mutations:multiple (human)
DNA:deletion, missense mutation:cds:p.D237_S238del, p.S206P (human)
RGD PMID:14615110 PMID:16189652 PMID:14566051 RGD:11352767, RGD:11531138, RGD:11352770 NCBI chr 1:194,721,279...194,781,149
Ensembl chr 1:194,719,134...194,774,557
JBrowse link
G Cfh complement component factor h ISO
IEA
DNA:mutations, polymorphisms:promoter, exon:multiple
OMIM:235400 | OMIM:612922 | OMIM:612923 | OMIM:612924 | OMIM:612925 | OMIM:612926
MouseDO
RGD
PMID:14583443 RGD:11041164 NCBI chr 1:140,013,593...140,111,149
Ensembl chr 1:140,012,446...140,111,502
JBrowse link
G Dgke diacylglycerol kinase, epsilon ISO ClinVar Annotator: match by term: Hemolytic-uremic syndrome ClinVar PMID:25854283 NCBI chr11:88,926,005...88,951,644
Ensembl chr11:88,926,005...88,957,676
JBrowse link
G Epo erythropoietin ISO CTD Direct Evidence: therapeutic CTD PMID:12053072 NCBI chr 5:137,481,282...137,484,078
Ensembl chr 5:137,481,282...137,531,504
JBrowse link
G F2 coagulation factor II ISO associated with diarrhea;protein:increased expression:plasma (human) RGD PMID:9423793 RGD:40818428 NCBI chr 2:91,442,742...91,466,802
Ensembl chr 2:91,455,665...91,466,759
JBrowse link
G Fos FBJ osteosarcoma oncogene IEP RGD PMID:15632024 RGD:7242276 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
JBrowse link
G Hp haptoglobin ISO RGD PMID:6218601 RGD:1626361 NCBI chr 8:110,301,760...110,305,804
Ensembl chr 8:110,301,760...110,305,804
JBrowse link
G Il1a interleukin 1 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:15384034 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
JBrowse link
G Il1b interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:15384034 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 severity ISO associated with Escherichia Coli Infections; RGD PMID:30467800 RGD:39458200 NCBI chr 1:40,444,025...40,504,578
Ensembl chr 1:40,468,730...40,504,575
JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO protein:increased concentration:serum (human) RGD PMID:9802632 PMID:12373296 RGD:6909134, RGD:6909171 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506
JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15384034 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Mbl2 mannose-binding lectin (protein C) 2 treatment ISO RGD PMID:27378476 RGD:11530050 NCBI chr19:30,210,306...30,217,087
Ensembl chr19:30,210,342...30,217,087
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12588957 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
JBrowse link
G Pla2g7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) severity ISO associated with Escherichia coli Infections; DNA:transversion mutation: :994 G>T (human) RGD PMID:10873870 RGD:7257516 NCBI chr17:43,878,885...43,923,093
Ensembl chr17:43,878,989...43,923,092
JBrowse link
G Plat plasminogen activator, tissue ISO associated with Escherichia coli Infections;protein:increased expression:plasma (human) RGD PMID:11777999 RGD:11541069 NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860
JBrowse link
G Thbd thrombomodulin IMP RGD PMID:22942429 RGD:11038690 NCBI chr 2:148,246,391...148,250,108
Ensembl chr 2:148,246,386...148,250,108
JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:15384034 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
hepatorenal syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edn1 endothelin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:7967349 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466
JBrowse link
G Hmox1 heme oxygenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21253390 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Sod1 superoxide dismutase 1, soluble IDA RGD PMID:15531919 RGD:1581228 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217
JBrowse link
G Tlr4 toll-like receptor 4 ISO mRNA, protein:increased expression:kidney RGD PMID:18093430 RGD:4144102 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521
JBrowse link
G Tnf tumor necrosis factor ISO protein:increased expression:plasma RGD PMID:18093430 RGD:4144102 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
HUPRA Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sars2 seryl-aminoacyl-tRNA synthetase 2 ISO ClinVar Annotator: match by term: HUPRA SYNDROME | ClinVar Annotator: match by term: HYPERURICEMIA, PULMONARY HYPERTENSION, RENAL FAILURE, AND ALKALOSIS SYNDROME
DNA:missense mutation:CDS:p.D390G (human)
OMIM
ClinVar
RGD
PMID:9536098 PMID:17576681 PMID:21255763 PMID:24034276 PMID:25741868 More... RGD:41410777 NCBI chr 7:28,441,393...28,453,304
Ensembl chr 7:28,441,417...28,453,296
JBrowse link
Kidney Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 ISO RGD PMID:21680852 RGD:6893484 NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790
JBrowse link
G Ace2 angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 ISO mRNA:decreased expression:kidney RGD PMID:20528771 RGD:9685432 NCBI chr  X:162,922,338...162,971,414
Ensembl chr  X:162,922,328...162,971,416
JBrowse link
G Adam17 a disintegrin and metallopeptidase domain 17 treatment ISO RGD PMID:22015440 RGD:13703100 NCBI chr12:21,373,510...21,423,633
Ensembl chr12:21,373,510...21,423,633
JBrowse link
G Adam2 a disintegrin and metallopeptidase domain 2 ISO RGD PMID:11967014 RGD:10047130 NCBI chr14:66,264,771...66,315,300
Ensembl chr14:66,264,778...66,315,182
JBrowse link
G Adamts1 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1 ISO RGD PMID:18272597 RGD:9684850 NCBI chr16:85,590,715...85,600,001
Ensembl chr16:85,590,715...85,600,001
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing treatment ISO RGD PMID:21412771 RGD:8695946 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778
JBrowse link
G Adm adrenomedullin treatment ISO protein:increased expression:serum: RGD PMID:20538296 PMID:20538296 RGD:7364948, RGD:7364948 NCBI chr 7:110,226,864...110,229,027
Ensembl chr 7:110,226,868...110,229,027
JBrowse link
G Akr1a1 aldo-keto reductase family 1, member A1 (aldehyde reductase) IMP RGD PMID:31089212 RGD:27226686 NCBI chr 4:116,493,707...116,508,871
Ensembl chr 4:116,493,707...116,508,877
JBrowse link
G Aldh2 aldehyde dehydrogenase 2, mitochondrial IMP RGD PMID:22022451 RGD:7241603 NCBI chr 5:121,704,090...121,731,887
Ensembl chr 5:121,704,090...121,731,887
JBrowse link
G Anxa1 annexin A1 treatment ISO RGD PMID:20953576 RGD:7421585 NCBI chr19:20,350,798...20,368,035
Ensembl chr19:20,350,792...20,368,308
JBrowse link
G Anxa5 annexin A5 ISO RGD PMID:21918686 RGD:7242028 NCBI chr 3:36,503,072...36,530,036
Ensembl chr 3:36,503,072...36,530,043
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 treatment ISO RGD PMID:26362957 RGD:13703110 NCBI chr10:90,825,173...90,918,688
Ensembl chr10:90,825,173...90,918,632
JBrowse link
G Apoa1 apolipoprotein A-I treatment ISO RGD PMID:18535924 RGD:7241574 NCBI chr 9:46,139,928...46,141,767
Ensembl chr 9:46,139,878...46,141,764
JBrowse link
G Atm ataxia telangiectasia mutated ISO protein:increased expression:kidney RGD PMID:22768306 RGD:10053607 NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040
JBrowse link
G Bax BCL2-associated X protein treatment ISO RGD PMID:23151253 RGD:10054101 NCBI chr 7:45,111,119...45,116,344
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 treatment ISO RGD PMID:18221257 PMID:29285062 RGD:2293026, RGD:13792599 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bdkrb1 bradykinin receptor, beta 1 IMP RGD PMID:18725957 RGD:7241559 NCBI chr12:105,570,350...105,571,770
Ensembl chr12:105,569,344...105,571,687
JBrowse link
G Becn1 beclin 1, autophagy related treatment ISO RGD PMID:26412257 RGD:11561958 NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112
JBrowse link
G Bnip3 BCL2/adenovirus E1B interacting protein 3 ISO mRNA, protein:increased expression:kidney RGD PMID:23698117 RGD:11561968 NCBI chr 7:138,492,565...138,511,235
Ensembl chr 7:138,492,565...138,511,248
JBrowse link
G C3 complement component 3 treatment ISO RGD PMID:19691975 RGD:7411689 NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136
JBrowse link
G Calca calcitonin/calcitonin-related polypeptide, alpha ISO RGD PMID:19194162 RGD:7204479 NCBI chr 7:114,225,223...114,236,145
Ensembl chr 7:114,230,713...114,235,592
JBrowse link
G Casp3 caspase 3 treatment ISO RGD PMID:23151253 RGD:10054101 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp7 caspase 7 ISO RGD PMID:17596683 RGD:5684536 NCBI chr19:56,382,640...56,430,780
Ensembl chr19:56,385,561...56,430,776
JBrowse link
G Ccl11 chemokine (C-C motif) ligand 11 treatment IDA RGD PMID:22160777 RGD:7247742 NCBI chr11:81,948,658...81,953,781
Ensembl chr11:81,948,649...81,953,781
JBrowse link
G Ccl2 chemokine (C-C motif) ligand 2 treatment IEP
ISO
mRNA, protein:increased expression:kidney, lung, serum RGD PMID:20396927 PMID:18650485 RGD:4891433, RGD:11526113 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Cd14 CD14 antigen IEP mRNA,protein:increased expression:kidney RGD PMID:10966493 RGD:7204444 NCBI chr18:36,858,117...36,859,868
Ensembl chr18:36,858,120...36,859,851
JBrowse link
G Cd40 CD40 antigen treatment ISO RGD PMID:25993320 RGD:11251055 NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868
JBrowse link
G Cfb complement factor B IMP RGD PMID:16467447 PMID:12538716 RGD:7242709, RGD:7242734 NCBI chr17:35,075,350...35,081,492
Ensembl chr17:35,075,350...35,081,494
JBrowse link
G Cfh complement component factor h treatment ISO protein:decreased expression:serum: RGD PMID:20538296 PMID:20538296 RGD:7364948, RGD:7364948 NCBI chr 1:140,013,593...140,111,149
Ensembl chr 1:140,012,446...140,111,502
JBrowse link
G Ciita class II transactivator IEP RGD PMID:14569092 RGD:7242896 NCBI chr16:10,297,877...10,348,928
Ensembl chr16:10,297,923...10,346,282
JBrowse link
G Csf1 colony stimulating factor 1 (macrophage) IMP
ISO
mRNA:increased expression:kidney RGD PMID:23143303 PMID:19196448 RGD:7257565, RGD:7257570 NCBI chr 3:107,648,364...107,668,048
Ensembl chr 3:107,648,364...107,667,785
JBrowse link
G Csf1r colony stimulating factor 1 receptor IMP RGD PMID:23143303 RGD:7257565 NCBI chr18:61,238,644...61,264,211
Ensembl chr18:61,233,670...61,265,221
JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 IMP
ISO
RGD PMID:22189844 PMID:9407517 RGD:7204675, RGD:7204727 NCBI chr 1:60,948,184...60,954,991
Ensembl chr 1:60,926,159...60,954,991
JBrowse link
G Cxcr2 chemokine (C-X-C motif) receptor 2 IMP RGD PMID:20038794 RGD:7257679 NCBI chr 1:74,193,153...74,200,405
Ensembl chr 1:74,193,148...74,200,405
JBrowse link
G Cxcr4 chemokine (C-X-C motif) receptor 4 ISO protein:increased expression:kidney RGD PMID:29073721 RGD:13825150 NCBI chr 1:128,515,936...128,520,036
Ensembl chr 1:128,515,936...128,520,030
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 treatment ISO RGD PMID:23552495 RGD:7244372 NCBI chr 9:54,073,221...54,175,448
Ensembl chr 9:54,073,221...54,175,394
JBrowse link
G Daxx Fas death domain-associated protein IEP
ISO
protein:increased expression:kidney: RGD PMID:18480747 PMID:18480747 RGD:9587836, RGD:9587836 NCBI chr17:34,128,379...34,134,564
Ensembl chr17:34,128,388...34,134,564
JBrowse link
G Ddr1 discoidin domain receptor family, member 1 IEP protein:increased expression:kidney (mouse) RGD PMID:31383731 RGD:151347540 NCBI chr17:35,992,459...36,015,633
Ensembl chr17:35,992,459...36,015,513
JBrowse link
G Dhfr dihydrofolate reductase ISO mRNA,protein:decreased expression:kidney: RGD PMID:18408363 RGD:11040540 NCBI chr13:92,491,291...92,525,561
Ensembl chr13:92,491,234...92,525,561
JBrowse link
G Drd3 dopamine receptor D3 treatment ISO RGD PMID:25989500 RGD:13506961