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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:kidney failure
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Accession:DOID:1074 term browser browse the term
Definition:A kidney disease characterized by the failure of the kidneys to adequately filter waste products from the blood. (DO)
Synonyms:exact_synonym: Kidney Insufficiencies;   Kidney Insufficiency;   Renal Failure;   Renal Failures;   Renal Insufficiencies;   kidney failures;   renal unsufficiency
 primary_id: MESH:D051437
 xref: ICD10CM:N19;   ICD9CM:586;   NCI:C4376
For additional species annotation, visit the Alliance of Genome Resources.



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kidney failure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme EXP CTD Direct Evidence: marker/mechanism CTD PMID:9259580 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380
JBrowse link
G ACMSD aminocarboxymuconate semialdehyde decarboxylase ISO RGD PMID:10966936 RGD:13831124 NCBI chr 2:134,838,616...134,902,034
Ensembl chr 2:134,838,616...134,902,034
JBrowse link
G ADAM10 ADAM metallopeptidase domain 10 EXP CTD Direct Evidence: marker/mechanism CTD PMID:32715474 NCBI chr15:58,588,809...58,749,707
Ensembl chr15:58,588,809...58,749,791
JBrowse link
G AGT angiotensinogen EXP CTD Direct Evidence: marker/mechanism CTD PMID:9259580 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576
JBrowse link
G AMBP alpha-1-microglobulin/bikunin precursor IEP RGD PMID:18046670 RGD:6904142 NCBI chr 9:114,060,127...114,078,300
Ensembl chr 9:114,060,127...114,078,328
JBrowse link
G APOE apolipoprotein E EXP CTD Direct Evidence: marker/mechanism CTD PMID:20842518 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393
JBrowse link
G CD80 CD80 molecule ISO RGD PMID:16893502 RGD:6902939 NCBI chr 3:119,524,293...119,559,614
Ensembl chr 3:119,524,293...119,559,614
JBrowse link
G CRP C-reactive protein severity IEP associated with Anemia, Sickle Cell; protein:increased expression:serum RGD PMID:20710104 RGD:6907441 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589
JBrowse link
G CYBA cytochrome b-245 alpha chain EXP CTD Direct Evidence: marker/mechanism CTD PMID:23325087 NCBI chr16:88,643,289...88,651,053
Ensembl chr16:88,643,275...88,651,083
JBrowse link
G CYP24A1 cytochrome P450 family 24 subfamily A member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:8164439 NCBI chr20:54,143,538...54,173,986
Ensembl chr20:54,153,446...54,173,986
JBrowse link
G DRD1 dopamine receptor D1 IAGP
IEA
DNA:polymorphism:5' utr:g.-94G>A (human) MouseDO
RGD
PMID:19675531 RGD:7248447 NCBI chr 5:175,440,036...175,444,182
Ensembl chr 5:175,440,036...175,444,182
JBrowse link
G EDN1 endothelin 1 onset ISO
EXP
protein:increased expression:kidney (rat)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:7967349 PMID:20888384 RGD:4144130 NCBI chr 6:12,256,484...12,297,194
Ensembl chr 6:12,290,361...12,297,194
JBrowse link
G EPO erythropoietin EXP CTD Direct Evidence: therapeutic CTD PMID:22013135 NCBI chr 7:100,720,468...100,723,700
Ensembl chr 7:100,720,468...100,723,700
JBrowse link
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit treatment IAGP
IEA
associated with Ovarian Neoplasms;DNA:SNPs: :8092C>A, 19007T>C (human) MouseDO
RGD
PMID:19786980 RGD:5688741 NCBI chr19:45,407,334...45,451,547
Ensembl chr19:45,407,334...45,478,828
JBrowse link
G GFER growth factor, augmenter of liver regeneration treatment IDA
IEA
associated with liver transplant; MouseDO
RGD
PMID:18929838 RGD:9685774 NCBI chr16:1,984,193...1,987,749
Ensembl chr16:1,984,193...1,987,749
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha ISO associated with Hypertension;protein:increased expression:kidney RGD PMID:15583217 RGD:1626324 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259
JBrowse link
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27469509 NCBI chr15:90,083,045...90,102,468
Ensembl chr15:90,083,045...90,102,477
JBrowse link
G IFNA2 interferon alpha 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:3597002 NCBI chr 9:21,384,255...21,385,398
Ensembl chr 9:21,384,255...21,385,398
JBrowse link
G IFNG interferon gamma EXP CTD Direct Evidence: marker/mechanism CTD PMID:3091246 PMID:8289579 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IL1B interleukin 1 beta ISO mRNA, protein:increased expression:kidney (mouse) RGD PMID:21907489 PMID:20722564 RGD:7175305, RGD:7175345 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G INS insulin EXP CTD Direct Evidence: marker/mechanism CTD PMID:8606734 PMID:9861226 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221
JBrowse link
G KL klotho ISO RGD PMID:10892340 RGD:1581732 NCBI chr13:33,016,243...33,066,143
Ensembl chr13:33,016,423...33,066,143
JBrowse link
G LEPR leptin receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:29988851 NCBI chr 1:65,420,652...65,641,559
Ensembl chr 1:65,420,652...65,641,559
JBrowse link
G MEFV MEFV innate immuity regulator, pyrin IAGP ClinVar Annotator: match by term: Renal failure ClinVar PMID:1977178 PMID:9668175 PMID:10090880 PMID:10611954 PMID:10612841 More... NCBI chr16:3,242,027...3,256,633
Ensembl chr16:3,242,027...3,256,633
JBrowse link
G MME membrane metalloendopeptidase EXP CTD Direct Evidence: marker/mechanism CTD PMID:10485324 NCBI chr 3:155,024,202...155,183,729
Ensembl chr 3:155,024,124...155,183,704
JBrowse link
G MT1A metallothionein 1A ISO associated with Cadmium Poisoning;mRNA:increased expression:kidney RGD PMID:16226777 RGD:6483854 NCBI chr16:56,638,666...56,640,087
Ensembl chr16:56,638,666...56,640,087
JBrowse link
G MT1F metallothionein 1F ISO associated with Cadmium Poisoning;mRNA:increased expression:kidney RGD PMID:16226777 RGD:6483854 NCBI chr16:56,657,959...56,659,303
Ensembl chr16:56,657,731...56,660,698
JBrowse link
G MT2A metallothionein 2A ISO associated with Cadmium Poisoning;mRNA:increased expression:kidney RGD PMID:16226777 RGD:6483854 NCBI chr16:56,608,584...56,609,497
Ensembl chr16:56,608,584...56,609,497
JBrowse link
G MTHFR methylenetetrahydrofolate reductase IAGP
IEA
DNA:transition:cds:g.677C>T (human) MouseDO
RGD
PMID:20433440 RGD:6893515 NCBI chr 1:11,785,723...11,805,964
Ensembl chr 1:11,785,723...11,806,455
JBrowse link
G NAMPT nicotinamide phosphoribosyltransferase treatment ISO RGD PMID:25594614 RGD:13781896 NCBI chr 7:106,248,298...106,285,888
Ensembl chr 7:106,248,298...106,285,966
JBrowse link
G NOTCH2 notch receptor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:32715474 NCBI chr 1:119,911,553...120,069,662
Ensembl chr 1:119,911,553...120,100,779
JBrowse link
G NOX4 NADPH oxidase 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23325087 NCBI chr11:89,324,353...89,589,557
Ensembl chr11:89,324,353...89,498,187
JBrowse link
G NPHS1 NPHS1 adhesion molecule, nephrin severity ISO protein:decreased expression:kidney (rat) RGD PMID:18346151 RGD:38599007 NCBI chr19:35,862,915...35,869,357
Ensembl chr19:35,825,964...35,869,287
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 ISO RGD PMID:19833176 RGD:10413912 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
JBrowse link
G PHEX phosphate regulating endopeptidase X-linked ISO mRNA:increased expression:parathroid gland,tibia: RGD PMID:14693675 RGD:11556273 NCBI chr  X:22,032,325...22,251,310
Ensembl chr  X:22,032,325...22,494,713
JBrowse link
G PKD1 polycystin 1, transient receptor potential channel interacting IAGP ClinVar Annotator: match by term: Renal insufficiency ClinVar NCBI chr16:2,088,708...2,135,898
Ensembl chr16:2,088,708...2,135,898
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma EXP CTD Direct Evidence: marker/mechanism CTD PMID:28182703 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
JBrowse link
G PPARGC1A PPARG coactivator 1 alpha ISO RGD PMID:22076434 RGD:7242044 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089
JBrowse link
G REN renin ISO RGD PMID:28533331 RGD:39939034 NCBI chr 1:204,154,819...204,166,337
Ensembl chr 1:204,154,819...204,190,324
JBrowse link
G RHCG Rh family C glycoprotein ISO protein:altered localization RGD PMID:17652373 RGD:9850158 NCBI chr15:89,471,407...89,496,583
Ensembl chr15:89,471,398...89,496,589
JBrowse link
G SERPINF1 serpin family F member 1 IEP protein:increased expression:plasma (human) RGD PMID:16828495 RGD:36174008 NCBI chr17:1,762,060...1,777,565
Ensembl chr17:1,762,029...1,777,565
JBrowse link
G SLC22A2 solute carrier family 22 member 2 ISO mRNA, protein:decreased expression:kidney cortex RGD PMID:21167265 RGD:7243878 NCBI chr 6:160,216,755...160,258,821
Ensembl chr 6:160,171,061...160,277,638
JBrowse link
G SLCO4C1 solute carrier organic anion transporter family member 4C1 ISO mRNA:decreased expression:kidney RGD PMID:14993604 RGD:1303977 NCBI chr 5:102,233,986...102,296,284
Ensembl chr 5:102,233,986...102,296,284
JBrowse link
G SPP1 secreted phosphoprotein 1 IEP In type 2 diabetic patients RGD PMID:21034455 RGD:6903271 NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532
JBrowse link
G TBXA2R thromboxane A2 receptor treatment ISO associated with Cholestasis; RGD PMID:9893136 RGD:11059601 NCBI chr19:3,594,507...3,606,875
Ensembl chr19:3,594,507...3,606,875
JBrowse link
G TLR2 toll like receptor 2 ISO RGD PMID:16177646 RGD:7241085 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,070...153,706,260
JBrowse link
G TLR4 toll like receptor 4 ISO
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:27585667 PMID:16177646 RGD:7241085 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735
JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B severity IEP associated with Neoplasms, Plasma Cell RGD PMID:9650354 RGD:7245537 NCBI chr 1:12,166,991...12,209,220
Ensembl chr 1:12,166,991...12,209,228
JBrowse link
G TSC1 TSC complex subunit 1 IAGP ClinVar Annotator: match by term: Renal insufficiency ClinVar PMID:10227394 PMID:10570911 PMID:15798777 PMID:23341583 PMID:25741868 More... NCBI chr 9:132,891,349...132,945,378
Ensembl chr 9:132,891,348...132,946,874
JBrowse link
G WFDC6 WAP four-disulfide core domain 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16436767 NCBI chr20:45,534,196...45,539,482
Ensembl chr20:45,534,196...45,539,482
JBrowse link
G XDH xanthine dehydrogenase treatment ISO associated with Hyperuricemia
DNA:nonsense mutation:CDS
RGD PMID:23137955 PMID:19667249 PMID:23024809 RGD:7247633, RGD:7247649, RGD:7247636 NCBI chr 2:31,334,321...31,414,742
Ensembl chr 2:31,334,321...31,414,742
JBrowse link
acute kidney failure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2M alpha-2-macroglobulin EXP CTD Direct Evidence: marker/mechanism CTD PMID:23052191 NCBI chr12:9,067,708...9,116,229
Ensembl chr12:9,067,664...9,116,229
JBrowse link
G ACE angiotensin I converting enzyme treatment ISO RGD PMID:24502693 RGD:11039053 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380
JBrowse link
G ADRB2 adrenoceptor beta 2 treatment ISO
IEA
IMP
associated with endotoxemia; protein:increased expression:kidney
associated with Endotoxemia;
associated with Bacteremia;
MouseDO
RGD
PMID:14747378 PMID:19020966 PMID:19887504 PMID:14747378 RGD:7175276, RGD:7175283, RGD:7175281, RGD:7175276 NCBI chr 5:148,826,611...148,828,623
Ensembl chr 5:148,826,611...148,828,623
JBrowse link
G AFM afamin EXP CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chr 4:73,481,745...73,504,001
Ensembl chr 4:73,481,745...73,504,001
JBrowse link
G AGER advanced glycosylation end-product specific receptor IDA
IEA
MouseDO
RGD
PMID:21811803 RGD:7243868 NCBI chr 6:32,180,969...32,184,253
Ensembl chr 6:32,180,968...32,184,322
JBrowse link
G AHSG alpha 2-HS glycoprotein EXP CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chr 3:186,613,060...186,621,318
Ensembl chr 3:186,613,060...186,621,318
JBrowse link
G ALAD aminolevulinate dehydratase ISO protein:decreased activity:kidney (rat) RGD PMID:19484701 RGD:4144146 NCBI chr 9:113,386,312...113,401,284
Ensembl chr 9:113,386,312...113,401,290
JBrowse link
G ALB albumin EXP CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:2048579 PMID:21259293 PMID:24361871 PMID:28885000 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482
JBrowse link
G ALOX5 arachidonate 5-lipoxygenase ISO RGD PMID:19194548 RGD:2317536 NCBI chr10:45,374,216...45,446,117
Ensembl chr10:45,374,176...45,446,119
JBrowse link
G AMBP alpha-1-microglobulin/bikunin precursor IMP
EXP
CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD
PMID:8963945 PMID:28885000 PMID:8963945 RGD:6904218 NCBI chr 9:114,060,127...114,078,300
Ensembl chr 9:114,060,127...114,078,328
JBrowse link
G AMN amnion associated transmembrane protein EXP CTD Direct Evidence: therapeutic CTD PMID:20514524 NCBI chr14:102,922,663...102,930,842
Ensembl chr14:102,922,663...102,933,596
JBrowse link
G ANXA1 annexin A1 treatment ISO RGD PMID:22101490 RGD:7421583 NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,393
JBrowse link
G AR androgen receptor ISO RGD PMID:24503548 RGD:11570523 NCBI chr  X:67,544,021...67,730,619
Ensembl chr  X:67,544,021...67,730,619
JBrowse link
G ARG1 arginase 1 ISO mRNA:decreased expression:renal tubule (rat) RGD PMID:12371970 RGD:631989 NCBI chr 6:131,573,226...131,584,329
Ensembl chr 6:131,470,832...131,584,332
JBrowse link
G ARG2 arginase 2 ISO mRNA:decreased expression:renal tubule (rat) RGD PMID:12371970 RGD:631989 NCBI chr14:67,619,920...67,651,708
Ensembl chr14:67,619,920...67,651,708
JBrowse link
G ATP5F1B ATP synthase F1 subunit beta ISO
EXP
CTD Direct Evidence: marker/mechanism CTD PMID:25666834 NCBI chr12:56,638,175...56,645,984
Ensembl chr12:56,638,175...56,645,984
JBrowse link
G AVP arginine vasopressin EXP CTD Direct Evidence: marker/mechanism CTD PMID:2139164 NCBI chr20:3,082,556...3,084,724
Ensembl chr20:3,082,556...3,084,724
JBrowse link
G AVPR1A arginine vasopressin receptor 1A ISO RGD PMID:17347933 RGD:2300348 NCBI chr12:63,142,759...63,151,201
Ensembl chr12:63,142,759...63,151,201
JBrowse link
G B2M beta-2-microglobulin ISO
EXP
protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:2689182 PMID:22005293 PMID:28885000 PMID:19536607 RGD:6482685 NCBI chr15:44,711,517...44,718,145
Ensembl chr15:44,711,358...44,718,851
JBrowse link
G BAD BCL2 associated agonist of cell death treatment ISO RGD PMID:20037173 RGD:10053672 NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704
JBrowse link
G BAX BCL2 associated X, apoptosis regulator treatment ISO
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:20623750 PMID:20037173 RGD:10053672 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BCL2 BCL2 apoptosis regulator ISO protein:increased expression:kidney RGD PMID:20037173 RGD:10053672 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BCL2L1 BCL2 like 1 ISO protein:increased expression:kidney RGD PMID:20037173 RGD:10053672 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989
JBrowse link
G BDKRB2 bradykinin receptor B2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24975837 NCBI chr14:96,204,839...96,244,164
Ensembl chr14:96,204,679...96,244,166
JBrowse link
G C3 complement C3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562
JBrowse link
G CAPN1 calpain 1 treatment ISO associated with Rhabdomyolysis; RGD PMID:24158126 RGD:13792553 NCBI chr11:65,181,373...65,212,006
Ensembl chr11:65,180,566...65,212,006
JBrowse link
G CASP1 caspase 1 ISO RGD PMID:16557226 RGD:2293624 NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250
JBrowse link
G CCL11 C-C motif chemokine ligand 11 ISO protein:increased expression:kidney RGD PMID:22778179 RGD:7247739 NCBI chr17:34,285,742...34,288,334
Ensembl chr17:34,285,742...34,288,334
JBrowse link
G CCL3 C-C motif chemokine ligand 3 IEP RGD PMID:20482449 RGD:6906908 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169
JBrowse link
G CCL5 C-C motif chemokine ligand 5 ISO protein:increased secretion:serum (mouse) RGD PMID:19508392 RGD:4889990 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
JBrowse link
G CCR5 C-C motif chemokine receptor 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26055553 NCBI chr 3:46,370,142...46,376,206
Ensembl chr 3:46,370,946...46,376,206
JBrowse link
G CCT7 chaperonin containing TCP1 subunit 7 EXP CTD Direct Evidence: marker/mechanism CTD PMID:31825490 NCBI chr 2:73,234,308...73,253,005
Ensembl chr 2:73,233,420...73,253,021
JBrowse link
G CD44 CD44 molecule (Indian blood group) EXP CTD Direct Evidence: marker/mechanism CTD PMID:23052191 NCBI chr11:35,139,171...35,232,402
Ensembl chr11:35,138,882...35,232,402
JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B ISO protein:decreased expression:kidney RGD PMID:16557226 RGD:2293624 NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,369
JBrowse link
G CLU clusterin ISO
EXP
protein:increased expression:urine
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:20118187 PMID:20623750 PMID:22005293 PMID:23052191 PMID:24361871 More... RGD:7245501 NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700
JBrowse link
G CP ceruloplasmin EXP CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chr 3:149,162,414...149,221,829
Ensembl chr 3:149,162,410...149,221,829
JBrowse link
G CRP C-reactive protein ISO
IEA
IDA
protein:increased expression:serum
associated with Myocardial Infarction;
MouseDO
RGD
PMID:22551254 PMID:22694718 RGD:6903282, RGD:6906888 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589
JBrowse link
G CSF1 colony stimulating factor 1 ISO RGD PMID:23143303 RGD:7257565 NCBI chr 1:109,910,506...109,930,992
Ensembl chr 1:109,910,242...109,930,992
JBrowse link
G CSF1R colony stimulating factor 1 receptor ISO RGD PMID:23143303 RGD:7257565 NCBI chr 5:150,053,295...150,113,365
Ensembl chr 5:150,053,291...150,113,372
JBrowse link
G CST3 cystatin C EXP CTD Direct Evidence: marker/mechanism CTD PMID:22005293 PMID:28885000 NCBI chr20:23,626,706...23,637,955
Ensembl chr20:23,626,706...23,638,473
JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 ISO mRNA:increased expression:kidney, liver, spleen RGD PMID:21677145 RGD:7175314 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 treatment ISO RGD PMID:19890363 PMID:18495746 RGD:7257732, RGD:7257735 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 treatment ISO RGD PMID:23981375 PMID:18495746 RGD:7257727, RGD:7257735 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607
JBrowse link
G CYP27B1 cytochrome P450 family 27 subfamily B member 1 ISO RGD PMID:6223803 RGD:2307326 NCBI chr12:57,762,334...57,767,078
Ensembl chr12:57,762,334...57,768,986
JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19814645 NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547
JBrowse link
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19814645 NCBI chr10:94,938,658...94,990,091
Ensembl chr10:94,938,658...94,990,091
JBrowse link
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19814645 NCBI chr22:42,126,499...42,130,810
Ensembl chr22:42,126,499...42,130,865
JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 treatment ISO RGD PMID:24717297 PMID:24412858 RGD:14700914, RGD:14700920 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
JBrowse link
G DDIT3 DNA damage inducible transcript 3 ISO Protein:increased expression:renal tubule epithelium RGD PMID:15476864 RGD:1599736 NCBI chr12:57,516,588...57,521,698
Ensembl chr12:57,516,588...57,521,737
JBrowse link
G ECE1 endothelin converting enzyme 1 ISO RGD PMID:11043448 PMID:10073607 RGD:7244180, RGD:7244185 NCBI chr 1:21,217,250...21,345,504
Ensembl chr 1:21,217,247...21,345,572
JBrowse link
G EDN1 endothelin 1 ISO
EXP
mRNA, protein:increased expression:kidney (mouse)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:9788586 PMID:19967049 RGD:4144852 NCBI chr 6:12,256,484...12,297,194
Ensembl chr 6:12,290,361...12,297,194
JBrowse link
G EGF epidermal growth factor IEP
ISO
mRNA:decreased expression:kidney RGD PMID:20482449 PMID:11340354 RGD:6906908, RGD:10395241 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766
JBrowse link
G EGFR epidermal growth factor receptor ISO
EXP
mRNA:increased expression:kidney
CTD Direct Evidence: therapeutic
CTD
RGD
PMID:14638913 PMID:11340354 RGD:10395241 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
JBrowse link
G EGLN1 egl-9 family hypoxia inducible factor 1 ISO mRNA, protein:decreased expression:kidney RGD PMID:19349364 RGD:11252083 NCBI chr 1:231,363,756...231,422,287
Ensembl chr 1:231,363,751...231,422,287
JBrowse link
G EGLN3 egl-9 family hypoxia inducible factor 3 ISO mRNA, protein:decreased expression:kidney RGD PMID:19349364 RGD:11252083 NCBI chr14:33,924,227...33,951,074
Ensembl chr14:33,924,227...34,462,774
JBrowse link
G EPAS1 endothelial PAS domain protein 1 treatment ISO RGD PMID:16762988 RGD:10395386 NCBI chr 2:46,297,407...46,386,697
Ensembl chr 2:46,293,667...46,386,697
JBrowse link
G EPHX2 epoxide hydrolase 2 EXP CTD Direct Evidence: therapeutic CTD PMID:26165641 NCBI chr 8:27,491,143...27,545,564
Ensembl chr 8:27,490,781...27,545,564
JBrowse link
G EPO erythropoietin treatment IDA
EXP
CTD Direct Evidence: therapeutic CTD
RGD
PMID:21847101 PMID:24561306 PMID:22209169 PMID:22235348 RGD:10400913, RGD:11041660 NCBI chr 7:100,720,468...100,723,700
Ensembl chr 7:100,720,468...100,723,700
JBrowse link
G FAS Fas cell surface death receptor IEP protein:increased expression:renal tubule (rat) RGD PMID:21374789 RGD:8663469 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605
JBrowse link
G FGA fibrinogen alpha chain ISO mRNA:increased expression:kidney (rat) RGD PMID:15805072 RGD:9685024 NCBI chr 4:154,583,126...154,590,742
Ensembl chr 4:154,583,128...154,590,745
JBrowse link
G FIS1 fission, mitochondrial 1 ISO protein:decreased expression:kidney (rat) RGD PMID:26480480 RGD:12910862 NCBI chr 7:101,239,472...101,245,081
Ensembl chr 7:101,239,458...101,252,316
JBrowse link
G FN1 fibronectin 1 ISO protein:increased expression:kidney RGD PMID:12884040 PMID:11768240 RGD:7205684, RGD:729934 NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073
JBrowse link
G FSTL1 follistatin like 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20861081 NCBI chr 3:120,392,293...120,450,992
Ensembl chr 3:120,392,293...120,450,993
JBrowse link
G G6PD glucose-6-phosphate dehydrogenase EXP CTD Direct Evidence: marker/mechanism CTD PMID:602954 PMID:734759 PMID:4794122 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,517,825...154,547,572
JBrowse link
G GAS6 growth arrest specific 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19564549 NCBI chr13:113,820,549...113,864,076
Ensembl chr13:113,820,549...113,864,076
JBrowse link
G GATM glycine amidinotransferase ISO protein:decreased activity:kidney (rat) RGD PMID:2752493 RGD:1599823 NCBI chr15:45,361,124...45,402,227
Ensembl chr15:45,361,124...45,402,327
JBrowse link
G GC GC vitamin D binding protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chr 4:71,741,693...71,805,520
Ensembl chr 4:71,741,696...71,804,041
JBrowse link
G GFER growth factor, augmenter of liver regeneration treatment ISO
EXP
protein:increased expression:cortex of kidney,renal medulla:
CTD Direct Evidence: therapeutic
CTD
RGD
PMID:20030531 PMID:20030531 PMID:20030531 RGD:9685736, RGD:9685736 NCBI chr16:1,984,193...1,987,749
Ensembl chr16:1,984,193...1,987,749
JBrowse link
G GHRL ghrelin and obestatin prepropeptide ISO RGD PMID:19625378 RGD:7242430 NCBI chr 3:10,285,666...10,292,947
Ensembl chr 3:10,285,666...10,292,947
JBrowse link
G GOT2 glutamic-oxaloacetic transaminase 2 ISO protein:decreased activity:kidney (rat) RGD PMID:23924727 RGD:13506245 NCBI chr16:58,707,131...58,734,316
Ensembl chr16:58,707,131...58,734,342
JBrowse link
G GPNMB glycoprotein nmb EXP CTD Direct Evidence: marker/mechanism CTD PMID:23052191 NCBI chr 7:23,246,775...23,275,108
Ensembl chr 7:23,235,967...23,275,108
JBrowse link
G GSK3B glycogen synthase kinase 3 beta EXP CTD Direct Evidence: marker/mechanism CTD PMID:22785175 NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994
JBrowse link
G GSR glutathione-disulfide reductase ISO glycerol-induced
protein:decreased activity:kidney:
RGD PMID:1870354 PMID:22286819 RGD:7257559, RGD:7257585 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
JBrowse link
G GSTA1 glutathione S-transferase alpha 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chr 6:52,791,371...52,803,816
Ensembl chr 6:52,791,371...52,803,860
JBrowse link
G GSTM2 glutathione S-transferase mu 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20623750 NCBI chr 1:109,668,057...109,683,997
Ensembl chr 1:109,668,022...109,709,551
JBrowse link
G GSTP1 glutathione S-transferase pi 1 IEP
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:20623750 PMID:20798258 RGD:6903954 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656
JBrowse link
G HAVCR1 hepatitis A virus cellular receptor 1 ISO
EXP
IEP
protein:increased expression:urine
CTD Direct Evidence: marker/mechanism
protein:increased expression:urine:
associated with Pyelonephritis;protein:increased expression:urine:
CTD
RGD
PMID:20118187 PMID:21259293 PMID:21835770 PMID:22005293 PMID:23052191 More... RGD:7244370, RGD:7245495, RGD:7245472 NCBI chr 5:157,029,413...157,069,407
Ensembl chr 5:157,026,742...157,069,396
JBrowse link
G HBEGF heparin binding EGF like growth factor ISO
EXP
mRNA:increased expression:kidney
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:7635938 PMID:11340354 RGD:10395241 NCBI chr 5:140,332,843...140,346,603
Ensembl chr 5:140,332,843...140,346,603
JBrowse link
G HBG2 hemoglobin subunit gamma 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:562503 PMID:851170 NCBI chr11:5,253,188...5,254,781
Ensembl chr11:5,253,188...5,505,605
JBrowse link
G HDAC2 histone deacetylase 2 treatment ISO associated with sepsis; RGD PMID:22933299 RGD:9590257 NCBI chr 6:113,933,028...113,971,148
Ensembl chr 6:113,933,028...114,011,308
JBrowse link
G HDAC3 histone deacetylase 3 ISO RGD PMID:21416250 RGD:10047111 NCBI chr 5:141,620,881...141,636,849
Ensembl chr 5:141,620,876...141,636,849
JBrowse link
G HDAC5 histone deacetylase 5 treatment ISO associated with sepsis; RGD PMID:22933299 PMID:21416250 RGD:9590257, RGD:10047111 NCBI chr17:44,076,753...44,123,641
Ensembl chr17:44,076,746...44,123,702
JBrowse link
G HES1 hes family bHLH transcription factor 1 ISO mRNA:increased expression:kidney collecting duct (rat)
protein:increased expression:kidney tubule (rat)
RGD PMID:24397211 PMID:24325066 RGD:9685383, RGD:9685389 NCBI chr 3:194,136,148...194,138,732
Ensembl chr 3:194,136,148...194,138,732
JBrowse link
G HEXB hexosaminidase subunit beta EXP CTD Direct Evidence: marker/mechanism CTD PMID:22005293 NCBI chr 5:74,640,023...74,721,288
Ensembl chr 5:74,640,023...74,722,647
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha treatment ISO mRNA:increased expression:renal cortex (rat) RGD PMID:18593636 PMID:16762988 PMID:15673301 RGD:9068894, RGD:10395386, RGD:10395376 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259
JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase ISO associated with Sepsis RGD PMID:16557230 RGD:5508471 NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001
JBrowse link
G HMOX1 heme oxygenase 1 treatment ISO
EXP
associated with Sepsis
CTD Direct Evidence: therapeutic
CTD
RGD
PMID:21048024 PMID:23807243 RGD:10755583 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G HP haptoglobin ISO
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:28885000 PMID:19270397 RGD:11041863 NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055
JBrowse link
G HPX hemopexin EXP CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chr11:6,431,049...6,440,987
Ensembl chr11:6,431,049...6,442,617
JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A EXP CTD Direct Evidence: marker/mechanism CTD PMID:12690470 PMID:19546256 NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946
JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 ISO protein:increased expression:kidney, lysosome (rat) RGD PMID:14966137 RGD:7242786 NCBI chr11:123,057,489...123,062,462
Ensembl chr11:123,057,489...123,063,230
JBrowse link
G ICAM1 intercellular adhesion molecule 1 treatment ISO RGD PMID:22659586 RGD:7175102 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
JBrowse link
G IFNA2 interferon alpha 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:12810204 NCBI chr 9:21,384,255...21,385,398
Ensembl chr 9:21,384,255...21,385,398
JBrowse link
G IGF1 insulin like growth factor 1 EXP CTD Direct Evidence: therapeutic CTD PMID:7540432 NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744
JBrowse link
G IGF1R insulin like growth factor 1 receptor ISO mRNA: decreased expression: kidney: both cortex and medulla RGD PMID:9767523 RGD:7242908 NCBI chr15:98,648,539...98,964,530
Ensembl chr15:98,648,539...98,964,530
JBrowse link
G IGFBP1 insulin like growth factor binding protein 1 EXP CTD Direct Evidence: therapeutic CTD PMID:7540432 NCBI chr 7:45,888,488...45,893,660
Ensembl chr 7:45,888,360...45,893,660
JBrowse link
G IGHG4 immunoglobulin heavy constant gamma 4 (G4m marker) ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chr14:105,624,476...105,626,065
Ensembl chr14:105,620,506...105,626,066
JBrowse link
G IL10 interleukin 10 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18460982 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL18 interleukin 18 ISO RGD PMID:11342578 RGD:6893450 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096
JBrowse link
G IL1A interleukin 1 alpha ISO RGD PMID:21716595 RGD:6907069 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
JBrowse link
G IL1B interleukin 1 beta ISO mRNA:increased expression:kidney, liver, spleen (mouse)
protein:increased expression:kidney (rat)
RGD PMID:22750969 PMID:21677145 PMID:22286667 PMID:22659586 RGD:7175094, RGD:7175314, RGD:7175258, RGD:7175102 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL1RN interleukin 1 receptor antagonist IDA
IEA
ISO
associated with Sepsis
associated with Asphyxia; rat model treated with human protein
MouseDO
RGD
PMID:16763508 PMID:14610321 PMID:16259926 RGD:6907360, RGD:6907375, RGD:6907369 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016
JBrowse link
G IL20 interleukin 20 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18496552 NCBI chr 1:206,863,565...206,869,223
Ensembl chr 1:206,865,623...206,869,223
JBrowse link
G IL6 interleukin 6 IEP
EXP
associated with Acute Lung Injury;protein:increased expression:plasma
CTD Direct Evidence: therapeutic
CTD
RGD
PMID:21570986 PMID:18074478 RGD:5128661 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G INS insulin EXP CTD Direct Evidence: marker/mechanism CTD PMID:12243603 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221
JBrowse link
G JAK2 Janus kinase 2 treatment ISO associated with Carcinoma, Lewis Lung, human cells in mouse model RGD PMID:31250048 RGD:149735351 NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,129,948
JBrowse link
G KLK1 kallikrein 1 EXP CTD Direct Evidence: therapeutic CTD PMID:18227104 NCBI chr19:50,819,146...50,823,787
Ensembl chr19:50,819,146...50,823,787
JBrowse link
G KNG1 kininogen 1 EXP CTD Direct Evidence: therapeutic CTD PMID:513486 PMID:3015452 NCBI chr 3:186,717,359...186,744,410
Ensembl chr 3:186,717,348...186,744,410
JBrowse link
G LCN2 lipocalin 2 ISO
IEP
EXP
protein:increased expression:urine
associated with open cardiac surgeries;protein:increased expression:urine:
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:20623750 PMID:22005293 PMID:23052191 PMID:27888128 PMID:28885000 More... RGD:7244370, RGD:126781714, RGD:125973912 NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453
JBrowse link
G LGALS3 galectin 3 ISO mRNA:increased expression:kidney RGD PMID:10980121 RGD:9685228 NCBI chr14:55,129,252...55,145,430
Ensembl chr14:55,124,110...55,145,423
JBrowse link
G LRG1 leucine rich alpha-2-glycoprotein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:34677723 NCBI chr19:4,536,402...4,540,036
Ensembl chr19:4,536,402...4,540,036
JBrowse link
G LRP2 LDL receptor related protein 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29286200 NCBI chr 2:169,127,109...169,362,534
Ensembl chr 2:169,127,109...169,362,534
JBrowse link
G MB myoglobin IEP
ISO
protein: increased expression: serum RGD PMID:23497406 PMID:9822635 RGD:7244253, RGD:7244259 NCBI chr22:35,606,764...35,623,354
Ensembl chr22:35,606,764...35,637,951
JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase ISO protein:increased expression:renal parenchyma (rat) RGD PMID:17940345 RGD:2317469 NCBI chr 7:116,672,196...116,798,377
Ensembl chr 7:116,672,196...116,798,377
JBrowse link
G MFN1 mitofusin 1 ISO protein:decreased expression:kidney (rat) RGD PMID:26480480 RGD:12910862 NCBI chr 3:179,347,709...179,394,936
Ensembl chr 3:179,347,709...179,394,936
JBrowse link
G MIR10A microRNA 10a EXP CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr17:48,579,838...48,579,947
Ensembl chr17:48,579,838...48,579,947
JBrowse link
G MIR122 microRNA 122 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr18:58,451,074...58,451,158
Ensembl chr18:58,451,074...58,451,158
JBrowse link
G MIR140 microRNA 140 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr16:69,933,081...69,933,180
Ensembl chr16:69,933,081...69,933,180
JBrowse link
G MIR143 microRNA 143 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr 5:149,428,918...149,429,023
Ensembl chr 5:149,428,918...149,429,023
JBrowse link
G MIR146B microRNA 146b EXP CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr10:102,436,512...102,436,584
Ensembl chr10:102,436,512...102,436,584
JBrowse link
G MIR148A microRNA 148a EXP CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr 7:25,949,919...25,949,986
Ensembl chr 7:25,949,919...25,949,986
JBrowse link
G MIR151A microRNA 151a ISO CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr 8:140,732,564...140,732,653
Ensembl chr 8:140,732,564...140,732,653
JBrowse link
G MIR152 microRNA 152 EXP CTD Direct Evidence: marker/mechanism CTD PMID:32583487 NCBI chr17:48,037,161...48,037,247
Ensembl chr17:48,037,161...48,037,247
JBrowse link
G MIR192 microRNA 192 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr11:64,891,137...64,891,246
Ensembl chr11:64,891,137...64,891,246
JBrowse link
G MIR215 microRNA 215 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr 1:220,117,853...220,117,962
Ensembl chr 1:220,117,853...220,117,962
JBrowse link
G MIR23A microRNA 23a EXP CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr19:13,836,587...13,836,659
Ensembl chr19:13,836,587...13,836,659
JBrowse link
G MIR25 microRNA 25 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr 7:100,093,560...100,093,643
Ensembl chr 7:100,093,560...100,093,643
JBrowse link
G MIR26A1 microRNA 26a-1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr 3:37,969,404...37,969,480
Ensembl chr 3:37,969,404...37,969,480
JBrowse link
G MIR30A microRNA 30a EXP CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr 6:71,403,551...71,403,621
Ensembl chr 6:71,403,551...71,403,621
JBrowse link
G MIR30D microRNA 30d EXP CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr 8:134,804,876...134,804,945
Ensembl chr 8:134,804,876...134,804,945
JBrowse link
G MIR486-1 microRNA 486-1 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:30682439 PMID:35279909 NCBI chr 8:41,660,441...41,660,508
Ensembl chr 8:41,660,441...41,660,508
JBrowse link
G MIR99A microRNA 99a EXP CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr21:16,539,089...16,539,169
Ensembl chr21:16,539,089...16,539,169
JBrowse link
G MIRLET7I microRNA let-7i EXP CTD Direct Evidence: marker/mechanism CTD PMID:30682439 NCBI chr12:62,603,686...62,603,769
Ensembl chr12:62,603,686...62,603,769
JBrowse link
G MPO myeloperoxidase IAGP
EXP
ISO
DNA:haplotye: :
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:20623750 PMID:22739978 PMID:19793022 RGD:6909168, RGD:6909185 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935
JBrowse link
G MTHFR methylenetetrahydrofolate reductase EXP CTD Direct Evidence: marker/mechanism CTD PMID:17387702 NCBI chr 1:11,785,723...11,805,964
Ensembl chr 1:11,785,723...11,806,455
JBrowse link
G MTOR mechanistic target of rapamycin kinase ISO RGD PMID:23022334 RGD:7245507 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556
JBrowse link
G MUC20 mucin 20, cell surface associated ISO RGD PMID:14565953 RGD:7364790 NCBI chr 3:195,720,978...195,733,551
Ensembl chr 3:195,720,884...195,741,123
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor susceptibility ISO protein:decreased phosphorylation:kidney (mouse) RGD PMID:23228991 RGD:7207407 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
JBrowse link
G NDUFB8 NADH:ubiquinone oxidoreductase subunit B8 ISO RGD PMID:22160772 RGD:13801199 NCBI chr10:100,523,729...100,529,923
Ensembl chr10:100,523,740...100,530,000
JBrowse link
G NES nestin ISO RGD PMID:24503548 RGD:11570523 NCBI chr 1:156,668,763...156,677,407
Ensembl chr 1:156,668,763...156,677,407
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 treatment ISO
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:24958931 PMID:24291173 RGD:10412697 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29286200 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302
JBrowse link
G NOS1 nitric oxide synthase 1 ISO RGD PMID:14531809 RGD:13825139 NCBI chr12:117,208,142...117,361,626
Ensembl chr12:117,208,142...117,452,170
JBrowse link
G NOS2 nitric oxide synthase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:9810145 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G NOS3 nitric oxide synthase 3 ISO
EXP
in females;mRNA:increased expression:cortex of kidney (rat)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:9788586 PMID:28947737 RGD:13450947 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
JBrowse link
G NPPA natriuretic peptide A ISO
EXP
mRNA:increased expression:kidney
CTD Direct Evidence: marker/mechanism|therapeutic
CTD
RGD
PMID:1825077 PMID:2948068 PMID:19298916 PMID:22209992 RGD:7247715 NCBI chr 1:11,845,709...11,847,783
Ensembl chr 1:11,845,709...11,848,345
JBrowse link
G NPPB natriuretic peptide B IEP
ISO
associated with lung diseases;protein:increased expression:serum:
mRNA:increased expression:kidney
associated with Myocardial Infarction;protein:increased expression:serum:
associated with Pneumonia;protein:increased expression:serum:
RGD PMID:23837838 PMID:22209992 PMID:23192919 PMID:23415693 RGD:7247620, RGD:7247715, RGD:7247624, RGD:7247622 NCBI chr 1:11,857,464...11,858,945
Ensembl chr 1:11,857,464...11,858,945
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 treatment ISO
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:26723870 PMID:28230744 RGD:13440091 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
JBrowse link
G OCLN occludin EXP CTD Direct Evidence: marker/mechanism CTD PMID:19766176 NCBI chr 5:69,492,547...69,558,104
Ensembl chr 5:69,492,292...69,558,104
JBrowse link
G ORM1 orosomucoid 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chr 9:114,323,098...114,326,479
Ensembl chr 9:114,323,098...114,326,479
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 ISO RGD PMID:21884784 RGD:5510015 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
JBrowse link
G PKD2 polycystin 2, transient receptor potential cation channel ISO protein:altered localization RGD PMID:12089381 RGD:7175293 NCBI chr 4:88,007,635...88,077,777
Ensembl chr 4:88,007,635...88,077,777
JBrowse link
G PLAT plasminogen activator, tissue type IEP protein:increased expression:plasma (human) RGD PMID:9767551 RGD:11541071 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709
JBrowse link
G PLG plasminogen EXP CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chr 6:160,702,193...160,754,097
Ensembl chr 6:160,702,238...160,754,097
JBrowse link
G POMC proopiomelanocortin EXP CTD Direct Evidence: therapeutic CTD PMID:17216604 NCBI chr 2:25,160,860...25,168,580
Ensembl chr 2:25,160,853...25,168,903
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma treatment ISO
EXP
CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD
PMID:20623750 PMID:24011919 PMID:24433871 PMID:17494862 RGD:8553020 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
JBrowse link
G PPARGC1A PPARG coactivator 1 alpha ISO associated with Endotoxemia; mRNA:decreased expression:kidney (mouse) RGD PMID:21881206 RGD:7242026 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089
JBrowse link
G PROC protein C, inactivator of coagulation factors Va and VIIIa treatment IDA
IEA
MouseDO
RGD
PMID:19092124 RGD:11250410 NCBI chr 2:127,418,427...127,429,242
Ensembl chr 2:127,418,427...127,429,242
JBrowse link
G PROCR protein C receptor treatment ISO associated with Sepsis RGD PMID:23807243 RGD:10755583 NCBI chr20:35,171,096...35,216,259
Ensembl chr20:35,172,072...35,216,240
JBrowse link
G PTAFR platelet activating factor receptor treatment ISO associated with Endotoxemia RGD PMID:2538527 RGD:10043182 NCBI chr 1:28,147,166...28,193,856
Ensembl chr 1:28,147,166...28,193,936
JBrowse link
G PTGER4 prostaglandin E receptor 4 treatment ISO RGD PMID:16871242 RGD:10003092 NCBI chr 5:40,679,915...40,746,800
Ensembl chr 5:40,679,915...40,693,735
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:21893983 RGD:5508181 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G RAPGEF3 Rap guanine nucleotide exchange factor 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21745194 NCBI chr12:47,734,363...47,758,880
Ensembl chr12:47,734,363...47,771,040
JBrowse link
G RB1 RB transcriptional corepressor 1 ISO associated with Sepsis;protein:increased phosphorylation:kidney RGD PMID:19428114 RGD:8547990 NCBI chr13:48,303,751...48,481,890
Ensembl chr13:48,303,744...48,599,436
JBrowse link
G REN renin exacerbates IEP Associated with toxic shock syndrome;protein:increased expression:blood plasma (human) RGD PMID:30407370 RGD:125097506 NCBI chr 1:204,154,819...204,166,337
Ensembl chr 1:204,154,819...204,190,324
JBrowse link
G SCGB1A1 secretoglobin family 1A member 1 ISO associated with LPS induced endotoxemia RGD PMID:18824919 RGD:2313129 NCBI chr11:62,419,033...62,423,195
Ensembl chr11:62,405,103...62,423,195
JBrowse link
G SERPINA1 serpin family A member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chr14:94,376,747...94,390,635
Ensembl chr14:94,376,747...94,390,693
JBrowse link
G SERPINC1 serpin family C member 1 IEP associated with heart failure; protein:decreased activity:plasma: RGD PMID:26108065 RGD:11354006 NCBI chr 1:173,903,800...173,917,327
Ensembl chr 1:173,903,800...173,917,327
JBrowse link
G SIRT1 sirtuin 1 severity ISO
EXP
protein:increased expression:kidney (rat)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:21416250 PMID:21416250 RGD:10047111 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390
JBrowse link
G SLC11A1 solute carrier family 11 member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20623750 NCBI chr 2:218,382,273...218,396,894
Ensembl chr 2:218,382,029...218,396,894
JBrowse link
G SLC22A1 solute carrier family 22 member 1 treatment ISO RGD PMID:22414646 RGD:7243179 NCBI chr 6:160,121,815...160,158,718
Ensembl chr 6:160,121,815...160,158,718
JBrowse link
G SLC22A12 solute carrier family 22 member 12 EXP CTD Direct Evidence: marker/mechanism CTD PMID:14655203 NCBI chr11:64,591,220...64,602,344
Ensembl chr11:64,590,641...64,602,353
JBrowse link
G SLC22A2 solute carrier family 22 member 2 treatment
susceptibility
ISO
IEA
IAGP
DNA:SNP: :808G>T (rs316019) human
mRNA:decreased expression:kidney
MouseDO
RGD
PMID:22414646 PMID:19625999 PMID:18612803 RGD:7243179, RGD:7243884, RGD:7243880 NCBI chr 6:160,216,755...160,258,821
Ensembl chr 6:160,171,061...160,277,638
JBrowse link
G SLC22A24 solute carrier family 22 member 24 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23649842 PMID:26230185 NCBI chr11:63,079,940...63,144,221
Ensembl chr11:63,079,940...63,144,221
JBrowse link
G SLC34A1 solute carrier family 34 member 1 disease_progression ISO associated with Sepsis; protein:decreased expression:renal proximal tubule (mouse) RGD PMID:19729856 RGD:7242943 NCBI chr 5:177,384,434...177,412,021
Ensembl chr 5:177,379,235...177,398,848
JBrowse link
G SOD1 superoxide dismutase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
JBrowse link
G SPP1 secreted phosphoprotein 1 ISO
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:11274264 PMID:20623750 PMID:22863853 RGD:6903264 NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532
JBrowse link
G TF transferrin EXP CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chr 3:133,661,998...133,796,641
Ensembl chr 3:133,746,040...133,796,641
JBrowse link
G TFF3 trefoil factor 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23052191 NCBI chr21:42,311,667...42,315,409
Ensembl chr21:42,311,667...42,315,409
JBrowse link
G TGFA transforming growth factor alpha ISO mRNA:increased expression:kidney RGD PMID:11340354 RGD:10395241 NCBI chr 2:70,447,284...70,553,826
Ensembl chr 2:70,447,284...70,554,193
JBrowse link
G TGFB1 transforming growth factor beta 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:10469268 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:34677723 NCBI chr 9:99,104,038...99,154,192
Ensembl chr 9:99,104,038...99,154,192
JBrowse link
G THBD thrombomodulin treatment ISO
IEA
IMP
MouseDO
RGD
PMID:19176699 PMID:17804460 RGD:5684994, RGD:5685010 NCBI chr20:23,045,633...23,049,672
Ensembl chr20:23,045,633...23,049,672
JBrowse link
G TLR2 toll like receptor 2 ISO
EXP
associated with Sepsis
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:29286200 PMID:22655058 RGD:7207898 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,070...153,706,260
JBrowse link
G TLR4 toll like receptor 4 treatment ISO
EXP
associated with Sepsis
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:29286200 PMID:22655058 PMID:16638912 PMID:22266601 RGD:7207898, RGD:7241084, RGD:6892690 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735
JBrowse link
G TLR9 toll like receptor 9 ISO associated with Sepsis RGD PMID:23548820 RGD:7245966 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645
JBrowse link
G TNF tumor necrosis factor susceptibility ISO
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:16595132 PMID:18460982 PMID:20623750 PMID:21150875 RGD:7245548 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TNFRSF12A TNF receptor superfamily member 12A EXP CTD Direct Evidence: marker/mechanism CTD PMID:23052191 NCBI chr16:3,020,368...3,022,383
Ensembl chr16:3,018,445...3,022,383
JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A susceptibility IEP
ISO
associated with Acute Lung Injury
associated with Endotoxemia
associated with Shock, Septic;protein:increased expression:serum
RGD PMID:18074478 PMID:21150875 PMID:12023385 PMID:12500222 RGD:5128661, RGD:7245548, RGD:7245535, RGD:7245534 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114
JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B IEP
ISO
associated with Acute Lung Injury
associated with Shock, Septic;protein:increased expression:serum
RGD PMID:18074478 PMID:12500222 PMID:12865254 RGD:5128661, RGD:7245534, RGD:7245532 NCBI chr 1:12,166,991...12,209,220
Ensembl chr 1:12,166,991...12,209,228
JBrowse link
G TP53 tumor protein p53 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20603111 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G TTR transthyretin EXP CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chr18:31,591,877...31,598,821
Ensembl chr18:31,557,009...31,598,833
JBrowse link
G UGT1A1 UDP glucuronosyltransferase family 1 member A1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:3864191 NCBI chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300
JBrowse link
G UGT1A9 UDP glucuronosyltransferase family 1 member A9 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20623750 NCBI chr 2:233,671,898...233,773,300
Ensembl chr 2:233,671,898...233,773,300
JBrowse link
G UOX urate oxidase (pseudogene) EXP CTD Direct Evidence: therapeutic CTD PMID:16313266 NCBI chr 1:84,364,958...84,384,801
Ensembl chr 1:84,363,706...84,397,831
JBrowse link
G UTS2R urotensin 2 receptor ISO RGD PMID:15146030 RGD:2306847 NCBI chr17:82,371,765...82,377,458
Ensembl chr17:82,371,765...82,377,458
JBrowse link
G VEGFA vascular endothelial growth factor A EXP CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:20943766 PMID:22808199 NCBI chr 6:43,770,209...43,786,487
Ensembl chr 6:43,770,184...43,786,487
JBrowse link
G WNT4 Wnt family member 4 ISO RGD PMID:12707392 RGD:727218 NCBI chr 1:22,117,313...22,143,097
Ensembl chr 1:22,117,313...22,143,969
JBrowse link
G XDH xanthine dehydrogenase treatment ISO associated with Reperfusion Injury RGD PMID:22571266 PMID:18539378 PMID:19628223 RGD:7247641, RGD:7247656, RGD:7247650 NCBI chr 2:31,334,321...31,414,742
Ensembl chr 2:31,334,321...31,414,742
JBrowse link
acute kidney tubular necrosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AK4 adenylate kinase 4 ISO protein:decreased expression:kidney (rat) RGD PMID:21152904 RGD:5134352 NCBI chr 1:65,147,552...65,232,145
Ensembl chr 1:65,147,549...65,232,145
JBrowse link
G BMP7 bone morphogenetic protein 7 ISO associated with Kidney Reperfusion Injury;protein:increased expression:kidney RGD PMID:16284088 RGD:1601494 NCBI chr20:57,168,753...57,266,641
Ensembl chr20:57,168,753...57,266,641
JBrowse link
G CCT7 chaperonin containing TCP1 subunit 7 EXP CTD Direct Evidence: marker/mechanism CTD PMID:31825490 NCBI chr 2:73,234,308...73,253,005
Ensembl chr 2:73,233,420...73,253,021
JBrowse link
G CIITA class II major histocompatibility complex transactivator ISO mRNA:increased expression:kidney RGD PMID:9422398 RGD:7242901 NCBI chr16:10,866,206...10,943,021
Ensembl chr16:10,866,222...10,943,021
JBrowse link
G FABP1 fatty acid binding protein 1 EXP CTD Direct Evidence: therapeutic CTD PMID:18368030 NCBI chr 2:88,122,982...88,128,062
Ensembl chr 2:88,122,982...88,128,062
JBrowse link
G GSR glutathione-disulfide reductase ISO protein:decreased activity:renal cortex: RGD PMID:17078987 PMID:12885594 RGD:7257555, RGD:7257573 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
JBrowse link
G HAVCR1 hepatitis A virus cellular receptor 1 IEP protein:increased expression:kidney tubule, urine: RGD PMID:12081583 RGD:7245970 NCBI chr 5:157,029,413...157,069,407
Ensembl chr 5:157,026,742...157,069,396
JBrowse link
G NOG noggin ISO associated with Kidney Reperfusion Injury RGD PMID:16284088 RGD:1601494 NCBI chr17:56,593,699...56,595,611
Ensembl chr17:56,593,699...56,595,611
JBrowse link
G POMC proopiomelanocortin EXP CTD Direct Evidence: marker/mechanism CTD PMID:4358912 PMID:6254450 NCBI chr 2:25,160,860...25,168,580
Ensembl chr 2:25,160,853...25,168,903
JBrowse link
G PPARA peroxisome proliferator activated receptor alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:19834340 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755
JBrowse link
G SOD2 superoxide dismutase 2 EXP CTD Direct Evidence: therapeutic CTD PMID:19917352 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
JBrowse link
G TEK TEK receptor tyrosine kinase ISO associated with Kidney Reperfusion Injury RGD PMID:16284088 RGD:1601494 NCBI chr 9:27,109,141...27,230,178
Ensembl chr 9:27,109,141...27,230,174
JBrowse link
ARC syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog EXP CTD Direct Evidence: marker/mechanism CTD PMID:20190753 NCBI chr14:77,426,675...77,457,601
Ensembl chr14:77,426,675...77,457,952
JBrowse link
G VPS33B VPS33B late endosome and lysosome associated EXP
IAGP
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Arthrogryposis with renal dysfunction and cholestasis syndrome
CTD
ClinVar
PMID:25741868 PMID:28492532 NCBI chr15:90,998,416...91,022,621
Ensembl chr15:90,998,673...91,022,603
JBrowse link
arthrogryposis, renal dysfunction, and cholestasis 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FBN1 fibrillin 1 IAGP ClinVar Annotator: match by term: Arthrogryposis, renal dysfunction, and cholestasis 1 ClinVar PMID:25741868 NCBI chr15:48,408,313...48,645,709
Ensembl chr15:48,408,313...48,645,721
JBrowse link
G VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog IAGP ClinVar Annotator: match by term: Arthrogryposis, renal dysfunction, and cholestasis 1 ClinVar PMID:25741868 PMID:31319225 NCBI chr14:77,426,675...77,457,601
Ensembl chr14:77,426,675...77,457,952
JBrowse link
G VPS33B VPS33B late endosome and lysosome associated IAGP ClinVar Annotator: match by term: Arthrogryposis, renal dysfunction, and cholestasis 1 OMIM
ClinVar
PMID:8151641 PMID:11668108 PMID:15052268 PMID:16896922 PMID:17994566 More... NCBI chr15:90,998,416...91,022,621
Ensembl chr15:90,998,673...91,022,603
JBrowse link
arthrogryposis, renal dysfunction, and cholestasis 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog IAGP ClinVar Annotator: match by term: Arthrogryposis, renal dysfunction, and cholestasis 2 ClinVar
OMIM
PMID:20190753 PMID:25741868 PMID:28492532 NCBI chr14:77,426,675...77,457,601
Ensembl chr14:77,426,675...77,457,952
JBrowse link
atypical hemolytic-uremic syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif 13 IEP
IAGP
protein:decreased activity:serum (human)
ClinVar Annotator: match by term: Atypical hemolytic uremic syndrome
ClinVar
RGD
PMID:12753286 PMID:17187257 PMID:17627784 PMID:23715102 PMID:25741868 More... RGD:10449096 NCBI chr 9:133,414,337...133,459,386
Ensembl chr 9:133,414,358...133,459,402
JBrowse link
G BAAT bile acid-CoA:amino acid N-acyltransferase IAGP ClinVar Annotator: match by term: HEMOLYTIC UREMIC SYNDROME, ATYPICAL, SUSCEPTIBILITY TO, 1 ClinVar NCBI chr 9:101,360,417...101,385,006
Ensembl chr 9:101,354,182...101,385,400
JBrowse link
G C2 complement C2 IAGP ClinVar Annotator: match by term: Atypical hemolytic uremic syndrome
ClinVar Annotator: match by term: AHUS, SUSCEPTIBILITY TO, 4
ClinVar Annotator: match by term: Atypical hemolytic-uremic syndrome
ClinVar PMID:2249879 PMID:6308626 PMID:8181962 PMID:16518403 PMID:16936732 More... NCBI chr 6:31,897,783...31,945,672
Ensembl chr 6:31,897,785...31,945,673
JBrowse link
G C3 complement C3 susceptibility ISO
IAGP
EXP
ClinVar Annotator: match by term: AHUS, SUSCEPTIBILITY TO, 5
ClinVar Annotator: match by term: Atypical hemolytic uremic syndrome
ClinVar Annotator: match by term: Hemolytic uremic syndrome, atypical
CTD Direct Evidence: marker/mechanism
DNA:missense mutations: :p.F603V, p.R1042L, p.I1157T (human)
ClinVar
CTD
OMIM
RGD
PMID:1976733 PMID:14639503 PMID:17634448 PMID:18325906 PMID:18796626 More... RGD:7364995, RGD:11040768 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562
JBrowse link
G C3AR1 complement C3a receptor 1 IAGP ClinVar Annotator: match by term: HEMOLYTIC UREMIC SYNDROME, ATYPICAL, SUSCEPTIBILITY TO, 1 ClinVar NCBI chr12:8,056,844...8,066,359
Ensembl chr12:8,056,844...8,066,359
JBrowse link
G CD46 CD46 molecule severity
susceptibility
IAGP
EXP
IEP
DNA:mutations:cds:multiple (human)
ClinVar Annotator: match by term: Familial Atypical Hemolytic-Uremic Syndrome
ClinVar Annotator: match by term: AHUS, SUSCEPTIBILITY TO, 2
ClinVar Annotator: match by term: Atypical hemolytic uremic syndrome
ClinVar Annotator: match by term: HEMOLYTIC UREMIC SYNDROME, ATYPICAL, SUSCEPTIBILITY TO, 2
CTD Direct Evidence: marker/mechanism
protein:increased expression:peripheral blood mononuclear cell (human)
DNA:snp:intron:c.IVS8+23T>G (rs2724374) (human)
DNA:missense mutations:cds:p.R69W, p.A304V (human)
ClinVar
OMIM
CTD
RGD
PMID:270646 PMID:3480783 PMID:9551389 PMID:14566051 PMID:14615110 More... RGD:11038684, RGD:11352810, RGD:11040768, RGD:11352768 NCBI chr 1:207,752,038...207,795,516
Ensembl chr 1:207,752,037...207,795,513
JBrowse link
G CFB complement factor B susceptibility IAGP
EXP
DNA, protein:mutations:cds: c.858C>G, F286L, c.967A>G, K323E (human)
ClinVar Annotator: match by term: AHUS, SUSCEPTIBILITY TO, 4
ClinVar Annotator: match by term: Atypical hemolytic-uremic syndrome
ClinVar Annotator: match by term: Atypical hemolytic uremic syndrome
ClinVar Annotator: match by term: AHUS, SUSCEPTIBILITY TO, 1
CTD Direct Evidence: marker/mechanism
DNA:nonsense mutations: :multiple
ClinVar
OMIM
CTD
RGD
PMID:2249879 PMID:6308626 PMID:7452889 PMID:8181962 PMID:16518403 More... RGD:7242707, RGD:11040768 NCBI chr 6:31,946,095...31,952,084
Ensembl chr 6:31,945,650...31,952,086
JBrowse link
G CFH complement factor H susceptibility IAGP
EXP
IEP
IDA
ISO
IMP
DNA:missense mutation
ClinVar Annotator: match by term: Hemolytic uremic syndrome, atypical, susceptibility to, 1
ClinVar Annotator: match by term: AHUS, SUSCEPTIBILITY TO, 1
ClinVar Annotator: match by term: AHUS, SUSCEPTIBILITY TO, 3
ClinVar Annotator: match by term: Atypical hemolytic uremic syndrome
ClinVar Annotator: match by term: AHUS, SUSCEPTIBILITY TO, 5
ClinVar Annotator: match by term: HEMOLYTIC UREMIC SYNDROME, ATYPICAL, SUSCEPTIBILITY TO, 1
CTD Direct Evidence: marker/mechanism
DNA:nonsense mutations, missense mutations, splice-site mutation: :multiple
DNA:deletion:Cds:
DNA:SNPs,Haplotype::
ClinVar
OMIM
CTD
RGD
PMID:646435 PMID:8072530 PMID:9536098 PMID:9551389 PMID:9811382 More... RGD:1599886, RGD:11041172, RGD:11041162, RGD:11040768, RGD:7364995, RGD:7364995, RGD:7364995 NCBI chr 1:196,652,043...196,747,504
Ensembl chr 1:196,651,754...196,752,476
JBrowse link
G CFHR1 complement factor H related 1 susceptibility IAGP
EXP
DNA:deletion
ClinVar Annotator: match by term: Hemolytic uremic syndrome, atypical
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Hemolytic uremic syndrome, atypical, susceptibility to
ClinVar Annotator: match by term: HEMOLYTIC UREMIC SYNDROME, ATYPICAL, SUSCEPTIBILITY TO, 1
ClinVar
CTD
OMIM
RGD
PMID:16998489 PMID:17367211 PMID:18006700 PMID:20843825 PMID:25741868 More... RGD:11041162 NCBI chr 1:196,819,731...196,832,189
Ensembl chr 1:196,819,731...196,837,159
JBrowse link
G CFHR3 complement factor H related 3 susceptibility IAGP
EXP
ClinVar Annotator: match by term: HEMOLYTIC UREMIC SYNDROME, ATYPICAL, SUSCEPTIBILITY TO, 1
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Hemolytic uremic syndrome, atypical, susceptibility to
ClinVar
CTD
OMIM
PMID:16998489 PMID:17367211 PMID:18006700 PMID:20843825 NCBI chr 1:196,774,840...196,795,407
Ensembl chr 1:196,774,813...196,795,407
JBrowse link
G CFHR5 complement factor H related 5 IAGP ClinVar Annotator: match by term: Atypical hemolytic uremic syndrome ClinVar NCBI chr 1:196,975,034...197,009,678
Ensembl chr 1:196,975,010...197,009,678
JBrowse link
G CFI complement factor I susceptibility IAGP
EXP
ClinVar Annotator: match by term: AHUS, SUSCEPTIBILITY TO, 3
ClinVar Annotator: match by term: Atypical hemolytic uremic syndrome
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
RGD
PMID:9536098 PMID:15173250 PMID:16621965 PMID:17576681 PMID:18557729 More... RGD:6906889 NCBI chr 4:109,730,982...109,801,999
Ensembl chr 4:109,731,008...109,802,150
JBrowse link
G COL4A5 collagen type IV alpha 5 chain IAGP ClinVar Annotator: match by term: Atypical hemolytic uremic syndrome ClinVar PMID:7599631 PMID:7695699 PMID:8218237 PMID:8651296 PMID:8940267 More... NCBI chr  X:108,439,838...108,697,545
Ensembl chr  X:108,439,838...108,697,545
JBrowse link
G DGKE diacylglycerol kinase epsilon IAGP
EXP
ClinVar Annotator: match by term: atypical hemolytic-uremic syndrome
ClinVar Annotator: match by term: Hemolytic uremic syndrome, atypical, susceptibility to, 7
ClinVar Annotator: match by term: Atypical hemolytic uremic syndrome
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
PMID:23542698 PMID:24511134 PMID:24747643 PMID:25741868 PMID:28492532 More... NCBI chr17:56,834,151...56,869,567
Ensembl chr17:56,834,107...56,869,567
JBrowse link
G MMACHC metabolism of cobalamin associated C IAGP ClinVar Annotator: match by term: Atypical hemolytic uremic syndrome ClinVar PMID:16311595 PMID:16714133 PMID:17768669 PMID:17853453 PMID:18164228 More... NCBI chr 1:45,500,300...45,513,382
Ensembl chr 1:45,500,300...45,513,382
JBrowse link
G PLG plasminogen IAGP ClinVar Annotator: match by term: Atypical hemolytic uremic syndrome ClinVar NCBI chr 6:160,702,193...160,754,097
Ensembl chr 6:160,702,238...160,754,097
JBrowse link
G SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1 IAGP ClinVar Annotator: match by term: Atypical hemolytic uremic syndrome
ClinVar Annotator: match by term: Atypical hemolytic-uremic syndrome
ClinVar PMID:28492532 NCBI chr 2:216,412,484...216,483,053
Ensembl chr 2:216,412,383...216,483,053
JBrowse link
G THBD thrombomodulin severity
susceptibility
no_association
IAGP
EXP
ClinVar Annotator: match by term: AHUS, SUSCEPTIBILITY TO, 6
ClinVar Annotator: match by term: Atypical hemolytic uremic syndrome
CTD Direct Evidence: marker/mechanism
DNA:SNPs:5' utr, 3' utr:multiple
DNA:missense mutations:CDS:multiple
ClinVar
OMIM
CTD
RGD
PMID:7811989 PMID:9157575 PMID:9236408 PMID:10460600 PMID:11245641 More... RGD:11038684, RGD:11038691, RGD:11038691 NCBI chr20:23,045,633...23,049,672
Ensembl chr20:23,045,633...23,049,672
JBrowse link
Autosomal Dominant Tubulointerstitial Kidney Disease 4 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC107548112 REN promoter and enhancer region IAGP ClinVar Annotator: match by term: Hyperuricemic nephropathy, familial juvenile, 2 ClinVar PMID:19664745 PMID:25741868 PMID:28492532 PMID:32750457 PMID:33532864 NCBI chr 1:204,162,166...204,178,479 JBrowse link
G REN renin IAGP ClinVar Annotator: match by term: Hyperuricemic nephropathy, familial juvenile, 2
ClinVar Annotator: match by term: TUBULOINTERSTITIAL KIDNEY DISEASE, AUTOSOMAL DOMINANT, 4
ClinVar
OMIM
PMID:16116425 PMID:19664745 PMID:25741868 PMID:28492532 PMID:32750457 More... NCBI chr 1:204,154,819...204,166,337
Ensembl chr 1:204,154,819...204,190,324
JBrowse link
Azotemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GH1 growth hormone 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:14728886 NCBI chr17:63,917,203...63,918,839
Ensembl chr17:63,917,200...63,918,839
JBrowse link
G REN renin EXP CTD Direct Evidence: marker/mechanism CTD PMID:6338847 NCBI chr 1:204,154,819...204,166,337
Ensembl chr 1:204,154,819...204,190,324
JBrowse link
Cardio-Renal Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HAVCR1 hepatitis A virus cellular receptor 1 susceptibility IEP
ISO
protein:increased expression:kidney tubule: RGD PMID:23220287 PMID:22367506 RGD:7245477, RGD:7245950 NCBI chr 5:157,029,413...157,069,407
Ensembl chr 5:157,026,742...157,069,396
JBrowse link
G MIR21 microRNA 21 ameliorates ISO RGD PMID:28760335 RGD:41410821 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337
JBrowse link
Chronic Allograft Nephropathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACO1 aconitase 1 ISO RGD PMID:20176611 RGD:11541086 NCBI chr 9:32,384,643...32,454,769
Ensembl chr 9:32,384,603...32,454,769
JBrowse link
G ALB albumin disease_progression IEP RGD PMID:24370342 RGD:11035281 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482
JBrowse link
G CCL3 C-C motif chemokine ligand 3 IEP RGD PMID:17298994 RGD:7241819 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169
JBrowse link
G CCN2 cellular communication network factor 2 disease_progression ISO mRNA, protein:increased expression:kidney (rat) RGD PMID:19921985 RGD:150517553 NCBI chr 6:131,948,176...131,951,372
Ensembl chr 6:131,948,176...131,951,372
JBrowse link
G CLU clusterin treatment ISO RGD PMID:22494435 RGD:9068431 NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700
JBrowse link
G MMP3 matrix metallopeptidase 3 IEP RGD PMID:22845765 RGD:7241226 NCBI chr11:102,835,801...102,843,609
Ensembl chr11:102,835,801...102,843,609
JBrowse link
G MMP7 matrix metallopeptidase 7 treatment ISO RGD PMID:18209025 RGD:9685339 NCBI chr11:102,520,508...102,530,747
Ensembl chr11:102,520,508...102,530,750
JBrowse link
G PDGFA platelet derived growth factor subunit A ISO RGD PMID:11889420 RGD:11080974 NCBI chr 7:497,258...520,700
Ensembl chr 7:497,258...520,296
JBrowse link
G PDGFB platelet derived growth factor subunit B ISO mRNA:increased expression:kidney: RGD PMID:15785371 PMID:11889420 RGD:10449491, RGD:11080974 NCBI chr22:39,223,359...39,244,982
Ensembl chr22:39,223,359...39,244,982
JBrowse link
G PDGFRA platelet derived growth factor receptor alpha ISO RGD PMID:11889420 RGD:11080974 NCBI chr 4:54,229,293...54,298,245
Ensembl chr 4:54,229,280...54,298,245
JBrowse link
G PDGFRB platelet derived growth factor receptor beta ISO RGD PMID:11889420 RGD:11080974 NCBI chr 5:150,113,839...150,155,845
Ensembl chr 5:150,113,839...150,155,872
JBrowse link
G PLAU plasminogen activator, urokinase IEP protein:increased secretion:T lymphocyte (human) RGD PMID:16387096 RGD:7241259 NCBI chr10:73,909,164...73,917,494
Ensembl chr10:73,909,177...73,917,496
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma IEP protein:increased expression:kidney: RGD PMID:16221712 RGD:13208600 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
JBrowse link
G SERPINE1 serpin family E member 1 treatment IEP
IMP
protein:increased expression:kidney: RGD PMID:16221712 PMID:18192922 RGD:13208600, RGD:13208601 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
JBrowse link
chronic kidney disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTN4 actinin alpha 4 IAGP ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 NCBI chr19:38,647,649...38,731,589
Ensembl chr19:38,647,649...38,731,589
JBrowse link
G AGER advanced glycosylation end-product specific receptor disease_progression
severity
susceptibility
IAGP
IEA
IDA
IEP
DNA:polymorphism:promoter:g.-374T>A (human)
DNA:polymorphisms:promoter, intron:g.-429T>C, g.2184A>G (human)
associated with Diabetes Mellitus, Type 2; DNA:polymorphism:promoter:g.-429T>C (human)
protein:increased expression:serum (human)
MouseDO
RGD
PMID:23593165 PMID:20185929 PMID:20353610 PMID:21432860 PMID:21822023 RGD:7243185, RGD:7242570, RGD:7244142, RGD:7243958, RGD:7243867 NCBI chr 6:32,180,969...32,184,253
Ensembl chr 6:32,180,968...32,184,322
JBrowse link
G AGTR1 angiotensin II receptor type 1 disease_progression ISO
IEA
IAGP
DNA:polymorphism:3' utr:1166A>C (human) MouseDO
RGD
PMID:12089373 PMID:12832734 RGD:6903863, RGD:8548869 NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008
JBrowse link
G AGTR2 angiotensin II receptor type 2 ISO RGD PMID:12089373 RGD:6903863 NCBI chr  X:116,170,744...116,174,974
Ensembl chr  X:116,170,744...116,174,974
JBrowse link
G AKAP12 A-kinase anchoring protein 12 susceptibility IAGP
IEA
DNA:polymorphism: :rs756009(human) MouseDO
RGD
PMID:19724895 RGD:14349027 NCBI chr 6:151,239,967...151,358,559
Ensembl chr 6:151,239,967...151,358,559
JBrowse link
G ANLN anillin, actin binding protein IAGP ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 PMID:28492532 NCBI chr 7:36,389,862...36,453,791
Ensembl chr 7:36,389,821...36,453,791
JBrowse link
G AOC3 amine oxidase copper containing 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23154672 NCBI chr17:42,851,199...42,858,124
Ensembl chr17:42,851,184...42,858,130
JBrowse link
G APOA1 apolipoprotein A1 IAGP ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 NCBI chr11:116,835,751...116,837,950
Ensembl chr11:116,835,751...116,837,622
JBrowse link
G APOA4 apolipoprotein A4 disease_progression IEP protein:increased expression:blood plasma (human) RGD PMID:21569504 RGD:5685637 NCBI chr11:116,820,700...116,823,304
Ensembl chr11:116,820,700...116,823,304
JBrowse link
G APOC3 apolipoprotein C3 IEP
IEA
IDA
protein:increased expression:plasma MouseDO
RGD
PMID:21829457 PMID:21297177 RGD:7207207, RGD:7207209 NCBI chr11:116,829,907...116,833,072
Ensembl chr11:116,829,706...116,833,072
JBrowse link
G ARHGDIA Rho GDP dissociation inhibitor alpha IAGP ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 NCBI chr17:81,867,721...81,871,337
Ensembl chr17:81,867,721...81,871,378
JBrowse link
G ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase IAGP ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 NCBI chr 2:215,312,059...215,368,592
Ensembl chr 2:215,311,956...215,349,773
JBrowse link
G AXDND1 axonemal dynein light chain domain containing 1 IAGP ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:8589695 PMID:10742096 PMID:11805166 PMID:15253708 PMID:15327385 More... NCBI chr 1:179,365,705...179,554,735
Ensembl chr 1:179,365,720...179,554,735
JBrowse link
G CBR1 carbonyl reductase 1 ISO mRNA, protein:decreased expression:liver RGD PMID:25332430 RGD:11565077 NCBI chr21:36,070,024...36,073,164
Ensembl chr21:36,069,941...36,073,166
JBrowse link
G CFH complement factor H IAGP ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 NCBI chr 1:196,652,043...196,747,504
Ensembl chr 1:196,651,754...196,752,476
JBrowse link
G CFHR1 complement factor H related 1 IAGP ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 NCBI chr 1:196,819,731...196,832,189
Ensembl chr 1:196,819,731...196,837,159
JBrowse link
G CFHR5 complement factor H related 5 IAGP ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:17000000 PMID:22503529 PMID:22527104 PMID:24033266 PMID:25260719 More... NCBI chr 1:196,975,034...197,009,678
Ensembl chr 1:196,975,010...197,009,678
JBrowse link
G CFI complement factor I IAGP ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 PMID:28492532 NCBI chr 4:109,730,982...109,801,999
Ensembl chr 4:109,731,008...109,802,150
JBrowse link
G CLU clusterin ISO associated with Obesity;protein:increased expression:urine RGD PMID:24325231 RGD:9068427 NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700
JBrowse link
G COL4A1 collagen type IV alpha 1 chain IAGP ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 PMID:28492532 NCBI chr13:110,148,963...110,307,157
Ensembl chr13:110,148,963...110,307,157
JBrowse link
G COL4A3 collagen type IV alpha 3 chain IAGP ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:14871398 PMID:17216251 PMID:24033266 PMID:24854265 PMID:25741868 More... NCBI chr 2:227,164,624...227,314,792
Ensembl chr 2:227,164,624...227,314,792
JBrowse link
G COL4A4 collagen type IV alpha 4 chain IAGP ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:12325029 PMID:21196518 PMID:24052634 PMID:24854265 PMID:25307543 More... NCBI chr 2:226,967,360...227,164,488
Ensembl chr 2:227,002,714...227,164,453
JBrowse link
G CPB2 carboxypeptidase B2 IAGP
IEA
DNA:polymorphism:cds :p.A147T(rs3742264)(human) MouseDO
RGD
PMID:19056482 RGD:7243119 NCBI chr13:46,053,186...46,105,033
Ensembl chr13:46,053,186...46,105,033
JBrowse link
G DGAT1 diacylglycerol O-acyltransferase 1 ISO protein:decreased expression:liver: RGD PMID:23045433 RGD:10400847 NCBI chr 8:144,314,584...144,326,852
Ensembl chr 8:144,314,584...144,326,910
JBrowse link
G DGAT2 diacylglycerol O-acyltransferase 2 ISO protein:decreased expression:liver: RGD PMID:23045433 RGD:10400847 NCBI chr11:75,768,778...75,801,534
Ensembl chr11:75,759,512...75,801,535
JBrowse link
G DNM1L dynamin 1 like treatment ISO RGD PMID:27801955 RGD:12738369 NCBI chr12:32,679,301...32,745,650
Ensembl chr12:32,679,200...32,745,650
JBrowse link
G DSTYK dual serine/threonine and tyrosine protein kinase IAGP ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 PMID:28492532 NCBI chr 1:205,142,505...205,211,702
Ensembl chr 1:205,142,505...205,211,702
JBrowse link
G EHHADH enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase IAGP ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 PMID:28492532 NCBI chr 3:185,190,624...185,254,049
Ensembl chr 3:185,190,624...185,281,990
JBrowse link
G ETFB electron transfer flavoprotein subunit beta IAGP ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 PMID:28492532 NCBI chr19:51,345,155...51,366,388
Ensembl chr19:51,345,169...51,366,388
JBrowse link
G FGF21 fibroblast growth factor 21 IEP protein:increased expression:serum: RGD PMID:22494291 RGD:10401925 NCBI chr19:48,755,524...48,758,330
Ensembl chr19:48,755,524...48,758,333
JBrowse link
G FGF23 fibroblast growth factor 23 ISO protein:increased expression:serum: RGD PMID:20016468 RGD:10044210 NCBI chr12:4,368,227...4,379,712
Ensembl chr12:4,368,227...4,379,712
JBrowse link
G FIS1 fission, mitochondrial 1 treatment ISO RGD PMID:27801955 RGD:12738369 NCBI chr 7:101,239,472...101,245,081
Ensembl chr 7:101,239,458...101,252,316
JBrowse link
G FN1 fibronectin 1 IAGP ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 PMID:28166811 PMID:28492532 NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073
JBrowse link
G FREM1 FRAS1 related extracellular matrix 1 IAGP ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 NCBI chr 9:14,737,152...14,910,995
Ensembl chr 9:14,737,152...14,910,995
JBrowse link
G GANAB glucosidase II alpha subunit IAGP ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 PMID:28492532 NCBI chr11:62,624,829...62,646,613
Ensembl chr11:62,624,826...62,646,726
JBrowse link
G GJA1 gap junction protein alpha 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:32045570 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727
JBrowse link
G GP1BA glycoprotein Ib platelet subunit alpha exacerbates IEP RGD PMID:11314805 RGD:42722629 NCBI chr17:4,932,277...4,935,023
Ensembl chr17:4,932,277...4,935,023
JBrowse link
G GPX1 glutathione peroxidase 1 treatment IDA
IEA
MouseDO
RGD
PMID:15954914 RGD:11352759 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,176...49,358,353
JBrowse link
G HAVCR1 hepatitis A virus cellular receptor 1 ISO RGD PMID:22269876 RGD:7245952 NCBI chr 5:157,029,413...157,069,407
Ensembl chr 5:157,026,742...157,069,396
JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase ISO mRNA, protein:increased expression:liver RGD PMID:12841361 RGD:1300058 NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001
JBrowse link
G HP haptoglobin ISO protein:increased expression:serum RGD PMID:18569920 RGD:11041800 NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055
JBrowse link
G IL19 interleukin 19 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24714768 NCBI chr 1:206,770,773...206,842,981
Ensembl chr 1:206,770,764...206,842,981
JBrowse link
G IL1B interleukin 1 beta IAGP
IEA
ISO
IEP
IDA
associated with Periodontitis; DNA:SNP:intron:g.3954C>T (human)
mRNA:increased expression:kidney (mouse)
protein:decreased expression:serum (human)
MouseDO
RGD
PMID:22795294 PMID:21975861 PMID:22398717 PMID:22613545 PMID:22728154 RGD:6906881, RGD:7175304, RGD:7175171, RGD:7175169, RGD:7175095 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL1RN interleukin 1 receptor antagonist susceptibility IEP
IEA
IAGP
protein:increased expression:plasma (human)
DNA:repeats:intron:IVS2+914_1000dup IL1RN*1 (human)
MouseDO
RGD
PMID:23024164 PMID:22795294 RGD:6906880, RGD:6906881 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016
JBrowse link
G INF2 inverted formin 2 IAGP ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 PMID:28492532 NCBI chr14:104,689,618...104,722,535
Ensembl chr14:104,681,146...104,722,535
JBrowse link
G INSR insulin receptor ISO protein:decreased phosphorylation:aorta RGD PMID:22942179 RGD:7207055 NCBI chr19:7,112,265...7,294,414
Ensembl chr19:7,112,255...7,294,414
JBrowse link
G KL klotho disease_progression
treatment
ISO
IEP
mRNA,protein:decreased expression:renal tubule, epithelial cell:
protein:decreased expression:urine:
protein:decreased expression:urine,plasma,kidney:
RGD PMID:11967236 PMID:21115613 PMID:21115613 PMID:11967236 RGD:70544, RGD:10403077, RGD:10403077, RGD:70544 NCBI chr13:33,016,243...33,066,143
Ensembl chr13:33,016,423...33,066,143
JBrowse link
G KLK1 kallikrein 1 susceptibility IAGP
IEA
associated with Vesico-Ureteral Reflux MouseDO
RGD
PMID:15086490 RGD:1581752 NCBI chr19:50,819,146...50,823,787
Ensembl chr19:50,819,146...50,823,787
JBrowse link
G LCN2 lipocalin 2 disease_progression EXP
ISO
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:24714768 PMID:20921623 RGD:126781837 NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453
JBrowse link
G LEPR leptin receptor ISO RGD PMID:32390513 PMID:27465994 RGD:34888223, RGD:12911217 NCBI chr 1:65,420,652...65,641,559
Ensembl chr 1:65,420,652...65,641,559
JBrowse link
G LOC107982234 WT1/WT1-AS bi-directional promoter region IAGP ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 NCBI chr11:32,430,848...32,437,423 JBrowse link
G LRRC37A2 leucine rich repeat containing 37 member A2 IAGP ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:34145744 NCBI chr17:46,372,792...47,049,128
Ensembl chr17:46,512,468...46,555,646
JBrowse link
G MFF-DT MFF divergent transcript IAGP ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:14871398 PMID:17216251 PMID:24033266 PMID:24854265 PMID:25741868 More... NCBI chr 2:227,221,052...227,325,164
Ensembl chr 2:227,221,052...227,325,711
JBrowse link
G MFN1 mitofusin 1 treatment ISO RGD PMID:27801955 RGD:12738369 NCBI chr 3:179,347,709...179,394,936
Ensembl chr 3:179,347,709...179,394,936
JBrowse link
G MT2A metallothionein 2A EXP CTD Direct Evidence: marker/mechanism CTD PMID:27122239 NCBI chr16:56,608,584...56,609,497
Ensembl chr16:56,608,584...56,609,497
JBrowse link
G MTHFR methylenetetrahydrofolate reductase susceptibility IAGP
IEA
DNA:polymorphism:cds:g.677C>T (human) MouseDO
RGD
PMID:23595572 RGD:7244284 NCBI chr 1:11,785,723...11,805,964
Ensembl chr 1:11,785,723...11,806,455
JBrowse link
G MYH9 myosin heavy chain 9 no_association IAGP RGD PMID:22956460 RGD:12798515 NCBI chr22:36,281,280...36,387,967
Ensembl chr22:36,281,280...36,388,010
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 treatment ISO RGD PMID:23174956 RGD:10412711 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
JBrowse link
G NGF nerve growth factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:24244623 NCBI chr 1:115,285,917...115,338,249
Ensembl chr 1:115,285,904...115,338,770
JBrowse link
G NOS3 nitric oxide synthase 3 susceptibility
treatment
ISO mRNA:decreased expression:cortex of kidney (rat) RGD PMID:29018182 PMID:29247650 RGD:13450920, RGD:13504713 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
JBrowse link
G NPHS1 NPHS1 adhesion molecule, nephrin severity IEP mRNA:increased expression:urine (human) RGD PMID:30133147 RGD:38549368 NCBI chr19:35,862,915...35,869,357
Ensembl chr19:35,825,964...35,869,287
JBrowse link
G NPHS2 NPHS2 stomatin family member, podocin IAGP ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:8589695 PMID:10742096 PMID:11729243 PMID:11805166 PMID:11854170 More... NCBI chr 1:179,550,539...179,575,948
Ensembl chr 1:179,550,539...179,575,952
JBrowse link
G NPPA natriuretic peptide A disease_progression IEP protein:increased expression:plasma RGD PMID:19052536 RGD:7247723 NCBI chr 1:11,845,709...11,847,783
Ensembl chr 1:11,845,709...11,848,345
JBrowse link
G NPPB natriuretic peptide B disease_progression IEP RGD PMID:23725445 RGD:7246908 NCBI chr 1:11,857,464...11,858,945
Ensembl chr 1:11,857,464...11,858,945
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 treatment ISO RGD PMID:22227174 RGD:10769366 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
JBrowse link
G NR4A1 nuclear receptor subfamily 4 group A member 1 disease_progression ISO RGD PMID:24722447 RGD:12910103 NCBI chr12:52,022,832...52,059,503
Ensembl chr12:52,022,832...52,059,507
JBrowse link
G OPA1 OPA1 mitochondrial dynamin like GTPase treatment ISO RGD PMID:27801955 RGD:12738369 NCBI chr 3:193,593,208...193,697,811
Ensembl chr 3:193,593,144...193,697,811
JBrowse link
G PASK PAS domain containing serine/threonine kinase IAGP ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 NCBI chr 2:241,106,099...241,150,347
Ensembl chr 2:241,106,099...241,150,264
JBrowse link
G PCSK2 proprotein convertase subtilisin/kexin type 2 ISO RGD PMID:18039782 RGD:6483556 NCBI chr20:17,226,107...17,484,578
Ensembl chr20:17,226,107...17,484,578
JBrowse link
G PKD1 polycystin 1, transient receptor potential channel interacting IAGP ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 NCBI chr16:2,088,708...2,135,898
Ensembl chr16:2,088,708...2,135,898
JBrowse link
G POSTN periostin IEP protein:increased secretion:urine:
protein:increased expression:kidney:
RGD PMID:22167593 PMID:22403621 RGD:10040972, RGD:10041032 NCBI chr13:37,562,585...37,598,768
Ensembl chr13:37,562,583...37,598,844
JBrowse link
G PPARGC1A PPARG coactivator 1 alpha ISO RGD PMID:22648295 RGD:7242023 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089
JBrowse link
G PTH parathyroid hormone severity
treatment
IEP
IEA
ISO
IDA
associated with Diabetes Mellitus, Type 2; protein:increased expression:serum (human)
protein:decreased expression:plasma (rat)
MouseDO
RGD
PMID:23528898 PMID:22517117 PMID:21826734 PMID:23345625 PMID:23467111 RGD:7242412, RGD:7242949, RGD:7242935, RGD:7242572, RGD:7242418 NCBI chr11:13,492,054...13,496,181
Ensembl chr11:13,492,054...13,496,181
JBrowse link
G RETN resistin EXP CTD Direct Evidence: marker/mechanism CTD PMID:22421264 NCBI chr19:7,669,049...7,670,455
Ensembl chr19:7,669,049...7,670,455
JBrowse link
G RNLS renalase, FAD dependent amine oxidase ISO protein, activity:decreased expression:plasma, heart, kidney: RGD PMID:18299506 RGD:7327164 NCBI chr10:88,171,523...88,583,318
Ensembl chr10:88,273,864...88,584,530
JBrowse link
G SHH sonic hedgehog signaling molecule ISO mRNA, protein:increased expression:kidney RGD PMID:24744439 PMID:24744439 RGD:12859042, RGD:12859042 NCBI chr 7:155,799,980...155,812,463
Ensembl chr 7:155,799,980...155,812,463
JBrowse link
G SLC19A1 solute carrier family 19 member 1 ISO mRNA:decreased expression:multiple (rat) RGD PMID:21149507 RGD:7327184 NCBI chr21:45,502,517...45,563,025
Ensembl chr21:45,493,572...45,573,365
JBrowse link
G SLC19A2 solute carrier family 19 member 2 ISO mRNA:decreased expression:liver, heart (rat) RGD PMID:21149507 RGD:7327184 NCBI chr 1:169,463,909...169,485,970
Ensembl chr 1:169,463,909...169,485,944
JBrowse link
G SLC19A3 solute carrier family 19 member 3 ISO mRNA:decreased expression:liver, heart, jejunum (rat) RGD PMID:21149507 RGD:7327184 NCBI chr 2:227,683,763...227,718,028
Ensembl chr 2:227,683,763...227,718,028
JBrowse link
G SLC34A1 solute carrier family 34 member 1 ISO
IEA
IAGP
mRNA:decreased expression:kidney (rat)
DNA:snp:intron:IVS9+122A>G rs6420094 (human)
MouseDO
RGD
PMID:21826734 PMID:20383146 RGD:7242935, RGD:7243100 NCBI chr 5:177,384,434...177,412,021
Ensembl chr 5:177,379,235...177,398,848
JBrowse link
G SLC46A1 solute carrier family 46 member 1 ISO mRNA:decreased expression:liver, heart, jejunum (rat) RGD PMID:21149507 RGD:7327184 NCBI chr17:28,394,642...28,406,592
Ensembl chr17:28,394,642...28,407,197
JBrowse link
G SLC9A3R1 SLC9A3 regulator 1 IAGP ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:18784102 PMID:25741868 PMID:28492532 NCBI chr17:74,748,628...74,769,353
Ensembl chr17:74,748,628...74,769,353
JBrowse link
G TBX18 T-box transcription factor 18 IAGP ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 NCBI chr 6:84,732,496...84,764,598
Ensembl chr 6:84,687,351...84,764,598
JBrowse link
G TERT telomerase reverse transcriptase treatment ISO RGD PMID:23013219 RGD:11038770 NCBI chr 5:1,253,167...1,295,068
Ensembl chr 5:1,253,147...1,295,068
JBrowse link
G TFCP2L1 transcription factor CP2 like 1 IAGP ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:33097957 NCBI chr 2:121,216,587...121,285,202
Ensembl chr 2:121,216,587...121,285,202
JBrowse link
G TLR9 toll like receptor 9 susceptibility IAGP
IEA
DNA:SNPs:promoter, exon:g.-1237T>C, g.1635G>A (rs5743836, rs352140) (human, Han Chinese) MouseDO
RGD
PMID:21908957 RGD:7246887 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645
JBrowse link
G TTC21B tetratricopeptide repeat domain 21B IAGP ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:24033266 PMID:25741868 PMID:28492532 NCBI chr 2:165,873,362...165,953,776
Ensembl chr 2:165,857,475...165,953,851
JBrowse link
G UMOD uromodulin IAGP ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 NCBI chr16:20,333,051...20,356,301
Ensembl chr16:20,333,051...20,356,301
JBrowse link
G VCAM1 vascular cell adhesion molecule 1 ISO
IEP
protein:increased expression:kidney
protein:increased expression:serum:
RGD PMID:20820841 PMID:21111939 RGD:4145364, RGD:7241036 NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045
JBrowse link
G WNT9B Wnt family member 9B IAGP ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:34145744 NCBI chr17:46,833,189...46,886,738
Ensembl chr17:46,833,201...46,886,730
JBrowse link
G WT1 WT1 transcription factor IAGP ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 NCBI chr11:32,387,775...32,435,539
Ensembl chr11:32,387,775...32,435,564
JBrowse link
G XDH xanthine dehydrogenase treatment ISO
IEA
IAGP
associated with Hypertension;DNA:SNP: :66292C>G (human) MouseDO
RGD
PMID:22622455 PMID:18712049 RGD:7247640, RGD:7247654 NCBI chr 2:31,334,321...31,414,742
Ensembl chr 2:31,334,321...31,414,742
JBrowse link
G ZNF423 zinc finger protein 423 IAGP ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 PMID:28492532 NCBI chr16:49,487,524...49,859,279
Ensembl chr16:49,487,524...49,857,919
JBrowse link
Contrast-Induced Nephropathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASP12 caspase 12 (gene/pseudogene) treatment ISO RGD PMID:27781957 RGD:13782262 NCBI chr11:104,885,718...104,898,460
Ensembl chr11:104,885,718...104,898,670
JBrowse link
G CASP3 caspase 3 treatment ISO RGD PMID:27781957 RGD:13782262 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
JBrowse link
G CRP C-reactive protein IDA associated with coronary disease; RGD PMID:23102387 RGD:6909166 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589
JBrowse link
G DDIT3 DNA damage inducible transcript 3 treatment ISO RGD PMID:27781957 RGD:13782262 NCBI chr12:57,516,588...57,521,698
Ensembl chr12:57,516,588...57,521,737
JBrowse link
G ECE1 endothelin converting enzyme 1 ISO mRNA,protein:increased expression:kidney medulla RGD PMID:18385664 RGD:7243946 NCBI chr 1:21,217,250...21,345,504
Ensembl chr 1:21,217,247...21,345,572
JBrowse link
G HAVCR1 hepatitis A virus cellular receptor 1 ISO protein:increased expression:urine: RGD PMID:23335628 RGD:7245471 NCBI chr 5:157,029,413...157,069,407
Ensembl chr 5:157,026,742...157,069,396
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 treatment ISO RGD PMID:27781957 RGD:13782262 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
JBrowse link
G IL1B interleukin 1 beta ISO associated with Diabetes Mellitus, Experimental RGD PMID:22094062 RGD:7175334 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G LCN2 lipocalin 2 ISO protein:increased expression:urine:
associated with Diabetes Mellitus, Experimental; protein:increased expression:urine
RGD PMID:23335628 PMID:23085980 RGD:7245471, RGD:7245484 NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453
JBrowse link
G MAPK8 mitogen-activated protein kinase 8 treatment ISO RGD PMID:27781957 RGD:13782262 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360
JBrowse link
G MIR188 microRNA 188 IEP
ISO
RNA:increased expression:plasma
RNA:increased expression:plasma, kidney
RGD PMID:27528406 PMID:27528406 RGD:35673289, RGD:35673289 NCBI chr  X:50,003,503...50,003,588
Ensembl chr  X:50,003,503...50,003,588
JBrowse link
G MIR30A microRNA 30a IEP
ISO
RNA:increased expression:plasma RGD PMID:27528406 PMID:27528406 RGD:35673289, RGD:35673289 NCBI chr 6:71,403,551...71,403,621
Ensembl chr 6:71,403,551...71,403,621
JBrowse link
G MIR30E microRNA 30e IEP
ISO
RNA:increased expression:plasma RGD PMID:27528406 PMID:27528406 RGD:35673289, RGD:35673289 NCBI chr 1:40,754,355...40,754,446
Ensembl chr 1:40,754,355...40,754,446
JBrowse link
G MPO myeloperoxidase ISO RGD PMID:20722568 RGD:6909183 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935
JBrowse link
G NPPA natriuretic peptide A IDA RGD PMID:19298916 RGD:7247719 NCBI chr 1:11,845,709...11,847,783
Ensembl chr 1:11,845,709...11,848,345
JBrowse link
G NPPB natriuretic peptide B IDA associated with Heart Failure RGD PMID:20438292 RGD:7248591 NCBI chr 1:11,857,464...11,858,945
Ensembl chr 1:11,857,464...11,858,945
JBrowse link
Diarrhea prodrome + Hemolytic-Uremic Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GP1BA glycoprotein Ib platelet subunit alpha IAGP associated with Escherichia Coli Infections;DNA:SNP:exon: (rs121908064) (human) RGD PMID:29216383 RGD:42722620 NCBI chr17:4,932,277...4,935,023
Ensembl chr17:4,932,277...4,935,023
JBrowse link
end stage renal disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA1 ATP binding cassette subfamily A member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19878707 NCBI chr 9:104,781,006...104,928,155
Ensembl chr 9:104,781,006...104,928,155
JBrowse link
G ABCB1 ATP binding cassette subfamily B member 1 ISO RGD PMID:17135344 RGD:2301067 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 ISO RGD PMID:17135344 RGD:2301067 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594
JBrowse link
G ABCC3 ATP binding cassette subfamily C member 3 ISO protein:decreased expression:intestine RGD PMID:17135344 RGD:2301067 NCBI chr17:50,634,881...50,692,253
Ensembl chr17:50,634,777...50,692,253
JBrowse link
G ABCG1 ATP binding cassette subfamily G member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19878707 NCBI chr21:42,199,689...42,297,244
Ensembl chr21:42,199,689...42,297,244
JBrowse link
G ACAT1 acetyl-CoA acetyltransferase 1 ISO
EXP
protein:increased expression:kidney (rat)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:19878707 PMID:19878707 RGD:2326081 NCBI chr11:108,116,705...108,147,603
Ensembl chr11:108,116,695...108,147,603
JBrowse link
G ACE angiotensin I converting enzyme treatment
susceptibility
IEA
EXP
ISO
IAGP
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Type 2;DNA:deletion:intron:IVS16+1464-1751del (human)
associated with Vesico-Ureteral Reflux;DNA:deletion
CTD
RGD
PMID:7593601 PMID:10099885 PMID:15118671 PMID:14586729 PMID:16385653 More... RGD:1331525, RGD:12879398, RGD:8142355, RGD:6903283 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380
JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing ISO
EXP
protein:increased expression:serum, urine
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:19539174 PMID:24028144 RGD:8695941 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463
JBrowse link
G ADIPOR1 adiponectin receptor 1 ISO
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:19539174 PMID:24028144 RGD:8695941 NCBI chr 1:202,940,825...202,958,572
Ensembl chr 1:202,940,826...202,958,572
JBrowse link
G ADIPOR2 adiponectin receptor 2 ISO RGD PMID:24028144 RGD:8695941 NCBI chr12:1,691,070...1,788,674
Ensembl chr12:1,688,574...1,788,674
JBrowse link
G ADRB2 adrenoceptor beta 2 IDA
IEA
MouseDO
RGD
PMID:9730702 RGD:7175286 NCBI chr 5:148,826,611...148,828,623
Ensembl chr 5:148,826,611...148,828,623
JBrowse link
G AGER advanced glycosylation end-product specific receptor IEP protein:increased expression:serum (human) RGD PMID:21822023 RGD:7243867 NCBI chr 6:32,180,969...32,184,253
Ensembl chr 6:32,180,968...32,184,322
JBrowse link
G AGT angiotensinogen IEA GAD PMID:15118671 RGD:1331525 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576
JBrowse link
G AGTR2 angiotensin II receptor type 2 IAGP
IEA
ISO
associated with Vesico-Ureteral Reflux;DNA:SNP: :-1332A>G (human) MouseDO
RGD
PMID:20149750 PMID:19212419 RGD:6903283, RGD:6903843 NCBI chr  X:116,170,744...116,174,974
Ensembl chr  X:116,170,744...116,174,974
JBrowse link
G ALB albumin disease_progression IEP
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:11938814 PMID:11849406 RGD:11036089 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482
JBrowse link
G APOA1 apolipoprotein A1 treatment IEP
ISO
protein:decreased expression:blood
protein:increased expression, increased glycation:plasma
associated with Hyperlipidemias
RGD PMID:22515595 PMID:18079481 PMID:20488818 RGD:7241208, RGD:7241576, RGD:7241571 NCBI chr11:116,835,751...116,837,950
Ensembl chr11:116,835,751...116,837,622
JBrowse link
G APOC2 apolipoprotein C2 IEP associated with Diabetes Mellitus, Insulin-Dependent RGD PMID:8139482 RGD:2313968 NCBI chr19:44,946,051...44,949,565
Ensembl chr19:44,946,035...44,949,565
JBrowse link
G APOC3 apolipoprotein C3 IEP associated with Diabetes Mellitus, Insulin-Dependent
protein:increased expression: :
RGD PMID:8139482 PMID:10822722 RGD:2313968, RGD:7207212 NCBI chr11:116,829,907...116,833,072
Ensembl chr11:116,829,706...116,833,072
JBrowse link
G APOE apolipoprotein E ISO
IEP
protein:increased expression:serum (human) RGD PMID:21705678 PMID:21332332 RGD:6903287, RGD:6904217 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393
JBrowse link
G ARG2 arginase 2 ISO protein:decreased activity:kidney (rat) RGD PMID:16809898 RGD:4110828 NCBI chr14:67,619,920...67,651,708
Ensembl chr14:67,619,920...67,651,708
JBrowse link
G BCL2 BCL2 apoptosis regulator treatment ISO RGD PMID:20424483 RGD:11522730 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BDKRB1 bradykinin receptor B1 resistance
no_association
IAGP
IEA
IEP
DNA: SNP: G-699-->C
DNA: SNP: G(-699)C
MouseDO
RGD
PMID:9555662 PMID:10604543 PMID:10809796 RGD:7241560, RGD:7241582, RGD:7241561 NCBI chr14:96,256,210...96,264,763
Ensembl chr14:96,256,210...96,268,967
JBrowse link
G BECN1 beclin 1 ISO protein:increased expression:kidney RGD PMID:24090408 RGD:11561926 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350
JBrowse link
G BGLAP bone gamma-carboxyglutamate protein IEP
ISO
protein:increased expression:serum RGD PMID:20845051 PMID:17365904 RGD:7207235, RGD:7207409 NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317
JBrowse link
G BNIP3 BCL2 interacting protein 3 ISO protein:increased expression:kidney RGD PMID:24090408 RGD:11561926 NCBI chr10:131,967,684...131,981,923
Ensembl chr10:131,967,684...131,981,967
JBrowse link
G C6 complement C6 severity ISO RGD PMID:11912252 RGD:1600675 NCBI chr 5:41,142,116...41,261,469
Ensembl chr 5:41,142,116...41,261,438
JBrowse link
G CASR calcium sensing receptor IEP protein:decreased expression:epigastric artery (human) RGD PMID:17537980 RGD:7205455 NCBI chr 3:122,183,668...122,291,629
Ensembl chr 3:122,183,668...122,291,629
JBrowse link
G CAT catalase ISO
EXP
protein: decreased expression :kidney
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:16518626 PMID:19420110 PMID:20007347 RGD:6892947 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CBR1 carbonyl reductase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26282591 NCBI chr21:36,070,024...36,073,164
Ensembl chr21:36,069,941...36,073,166
JBrowse link
G CCL2 C-C motif chemokine ligand 2 susceptibility
treatment
IAGP
EXP
ISO
associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism:promoter:-2518A>G (human)
CTD Direct Evidence: marker/mechanism
protein:increased expression:renal proximal tubule (rat)
CTD
RGD
PMID:19420110 PMID:19539174 PMID:17982227 PMID:18797164 PMID:12080327 RGD:2306990, RGD:2307007, RGD:8549739 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
JBrowse link
G CCL3 C-C motif chemokine ligand 3 IEP RGD PMID:22613545 RGD:7175169 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169
JBrowse link
G CCL5 C-C motif chemokine ligand 5 ISO mRNA:increased expression:kidney cortex (rat) RGD PMID:19535570 RGD:4889989 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
JBrowse link
G CCR1 C-C motif chemokine receptor 1 ISO associated with Candidiasis, Invasive; RGD PMID:22916017 RGD:7241817 NCBI chr 3:46,201,711...46,208,313
Ensembl chr 3:46,201,711...46,208,313
JBrowse link
G CCR5 C-C motif chemokine receptor 5 ISO mRNA:increased expression:kidney cortex (rat) RGD PMID:19535570 RGD:4889989 NCBI chr 3:46,370,142...46,376,206
Ensembl chr 3:46,370,946...46,376,206
JBrowse link
G CD2AP CD2 associated protein ISS MouseDO NCBI chr 6:47,477,789...47,627,263
Ensembl chr 6:47,477,789...47,627,263
JBrowse link
G CD40 CD40 molecule treatment
severity
IDA
IEA
IEP
protein:increased expression:plasma MouseDO
RGD
PMID:12941150 PMID:20846521 RGD:7248709, RGD:7248723 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863
JBrowse link
G CD40LG CD40 ligand IEP protein:increased expression:plasma RGD PMID:19019166 RGD:7248427 NCBI chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390
JBrowse link
G CD68 CD68 molecule EXP CTD Direct Evidence: marker/mechanism CTD PMID:19539174 NCBI chr17:7,579,638...7,582,111
Ensembl chr17:7,579,491...7,582,111
JBrowse link
G CFB complement factor B severity ISO
IEP
RGD PMID:17522263 PMID:1837062 RGD:7242704, RGD:7242753 NCBI chr 6:31,946,095...31,952,084
Ensembl chr 6:31,945,650...31,952,086
JBrowse link
G CHGA chromogranin A IEP
IEA
IAGP
protein:increased expression:serum
associated with Hypertension;DNA:polymorphisms, haplotypes:promoter, 3' utr:multiple
MouseDO
RGD
PMID:20730520 PMID:18235090 RGD:6906898, RGD:6906903 NCBI chr14:92,922,664...92,935,285
Ensembl chr14:92,923,150...92,935,285
JBrowse link
G COL1A1 collagen type I alpha 1 chain IEP RGD PMID:25782334 RGD:11041185 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632
JBrowse link
G COL3A1 collagen type III alpha 1 chain IAGP
IEA
DNA:polymorphism: :p.I1205V (human) MouseDO
RGD
PMID:19424605 RGD:7257553 NCBI chr 2:188,974,373...189,012,746
Ensembl chr 2:188,974,373...189,012,746
JBrowse link
G COL4A3 collagen type IV alpha 3 chain IAGP
IEA
MouseDO
RGD
PMID:19357112 RGD:7242047 NCBI chr 2:227,164,624...227,314,792
Ensembl chr 2:227,164,624...227,314,792
JBrowse link
G COL4A4 collagen type IV alpha 4 chain IAGP
IEA
ClinVar Annotator: match by term: End-stage renal failure MouseDO
ClinVar
RGD
PMID:24033266 PMID:25741868 PMID:28492532 PMID:19357112 RGD:7242047 NCBI chr 2:226,967,360...227,164,488
Ensembl chr 2:227,002,714...227,164,453
JBrowse link
G CPT1A carnitine palmitoyltransferase 1A EXP CTD Direct Evidence: marker/mechanism CTD PMID:19878707 NCBI chr11:68,754,620...68,844,277
Ensembl chr11:68,754,620...68,844,410
JBrowse link
G CRP C-reactive protein disease_progression IEP
EXP
protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:19539174 PMID:22865783 RGD:6906886 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589
JBrowse link
G CSF1 colony stimulating factor 1 IEP protein:increased expression:plasma RGD PMID:11340249 RGD:7257586 NCBI chr 1:109,910,506...109,930,992
Ensembl chr 1:109,910,242...109,930,992
JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 IAGP
IEA
associated with Wegener Granulomatosis;DNA:polymorphisms:promoter,exon::-318C>T, (AT)repeats (human) MouseDO
RGD
PMID:15708894 RGD:7204725 NCBI chr 2:203,867,771...203,873,965
Ensembl chr 2:203,853,888...203,873,965
JBrowse link
G CXCR1 C-X-C motif chemokine receptor 1 IEP RGD PMID:20649681 RGD:7207863 NCBI chr 2:218,162,841...218,166,962
Ensembl chr 2:218,162,841...218,166,962
JBrowse link
G CXCR2 C-X-C motif chemokine receptor 2 IAGP
IEA
DNA:polymorphism: :1208C>T (human) MouseDO
RGD
PMID:23615182 RGD:7257672 NCBI chr 2:218,125,294...218,137,251
Ensembl chr 2:218,125,289...218,137,251
JBrowse link
G CYBA cytochrome b-245 alpha chain ISO
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:19420110 PMID:19420110 RGD:2306994 NCBI chr16:88,643,289...88,651,053
Ensembl chr16:88,643,275...88,651,083
JBrowse link
G CYBB cytochrome b-245 beta chain ISO
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:19420110 PMID:15550752 RGD:1599682 NCBI chr  X:37,780,059...37,813,461
Ensembl chr  X:37,780,018...37,813,461
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 IAGP
IEA
ISO
DNA:polymorphisms:exon, 3' utr:3801T>C (rs4646903), p.I462V (rs1048943) (human)
mRNA, protein:decreased expression:intestine
MouseDO
RGD
PMID:23619522 PMID:12039987 RGD:7257728, RGD:7296923 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15248218 NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398
JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15248218 NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547
JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 IAGP
IEA
DNA:polymorphisms: : MouseDO
RGD
PMID:18769365 RGD:7243146 NCBI chr10:95,036,772...95,069,497
Ensembl chr10:95,036,772...95,069,497
JBrowse link
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 ISO RGD PMID:11158222 PMID:8531418 RGD:6903939, RGD:6903940 NCBI chr10:94,938,658...94,990,091
Ensembl chr10:94,938,658...94,990,091
JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 ISO mRNA, protein:decreased expression:intestine RGD PMID:12039987 RGD:7296923 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248
JBrowse link
G DDC dopa decarboxylase ISO protein:altered activity:renal cortex (rat) RGD PMID:19167406 RGD:5128880 NCBI chr 7:50,458,442...50,565,405
Ensembl chr 7:50,458,436...50,565,405
JBrowse link
G DRD1 dopamine receptor D1 treatment ISO RGD PMID:18402547 RGD:7248448 NCBI chr 5:175,440,036...175,444,182
Ensembl chr 5:175,440,036...175,444,182
JBrowse link
G DRD2 dopamine receptor D2 IAGP
IEA
associated with Diabetes Mellitus, Non-Insulin Dependent; DNA:polymorphisms:5'utr, intron: -141delC, G>A (human) MouseDO
RGD
PMID:18366720 RGD:2311602 NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691
JBrowse link
G EDN1 endothelin 1 ISO mRNA:increased expression:kidney (rat) RGD PMID:8441230 RGD:4144849 NCBI chr 6:12,256,484...12,297,194
Ensembl chr 6:12,290,361...12,297,194
JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 IAGP
IEA
Associated with Type 2 diabetes MouseDO
RGD
PMID:18184924 RGD:6906927 NCBI chr 6:131,808,020...131,895,155
Ensembl chr 6:131,808,016...131,895,155
JBrowse link
G EPHX2 epoxide hydrolase 2 disease_progression ISO RGD PMID:20694143 RGD:5688726 NCBI chr 8:27,491,143...27,545,564
Ensembl chr 8:27,490,781...27,545,564
JBrowse link
G EPO erythropoietin EXP CTD Direct Evidence: therapeutic CTD PMID:16707910 NCBI chr 7:100,720,468...100,723,700
Ensembl chr 7:100,720,468...100,723,700
JBrowse link
G EPOR erythropoietin receptor ISO protein:decreased expression:heart RGD PMID:27468524 RGD:11532749 NCBI chr19:11,377,207...11,384,314
Ensembl chr19:11,377,207...11,384,342
JBrowse link
G F2 coagulation factor II, thrombin treatment ISO RGD PMID:22473220 RGD:7387323 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
JBrowse link
G F5 coagulation factor V IAGP
IEA
DNA:mutation: :1691G>A(human) MouseDO
RGD
PMID:19520684 RGD:6893522 NCBI chr 1:169,511,951...169,586,481
Ensembl chr 1:169,511,951...169,586,588
JBrowse link
G FABP1 fatty acid binding protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19878707 NCBI chr 2:88,122,982...88,128,062
Ensembl chr 2:88,122,982...88,128,062
JBrowse link
G FABP2 fatty acid binding protein 2 IAGP
IEA
DNA:polymorphism:CDS:amino acid A54T, associated with Diabetes Mellitus, Type 2 (MeSH:D003924) MouseDO
RGD
PMID:16249461 RGD:1578457 NCBI chr 4:119,317,250...119,322,138
Ensembl chr 4:119,317,250...119,322,138
JBrowse link
G FASN fatty acid synthase EXP CTD Direct Evidence: marker/mechanism CTD PMID:19878707 NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294
JBrowse link
G FCGR2B Fc gamma receptor IIb IEP RGD PMID:15266033 RGD:7240530 NCBI chr 1:161,647,243...161,678,654
Ensembl chr 1:161,663,143...161,678,654
JBrowse link
G FGB fibrinogen beta chain treatment IAGP
IEA
associated with hypertension;DNA:polymorphism: :-455G>A (human) MouseDO
RGD
PMID:19352213 RGD:7175505 NCBI chr 4:154,562,980...154,572,807
Ensembl chr 4:154,563,011...154,572,807
JBrowse link
G FN1 fibronectin 1 IEP protein:decreased expression:plasma RGD PMID:6665521 RGD:7205701 NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073
JBrowse link
G GATA3 GATA binding protein 3 EXP
IAGP
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Stage 5 chronic kidney disease
CTD
ClinVar
PMID:25741868 PMID:26970513 NCBI chr10:8,045,333...8,075,198
Ensembl chr10:8,045,378...8,075,198
JBrowse link
G GCKR glucokinase regulator IMP
IEA
DNA: snp: rs1260326 MouseDO
RGD
PMID:21980298 RGD:7242279 NCBI chr 2:27,496,839...27,523,684
Ensembl chr 2:27,496,839...27,523,684
JBrowse link
G GHRL ghrelin and obestatin prepropeptide IEP RGD PMID:18809976 RGD:7242553 NCBI chr 3:10,285,666...10,292,947
Ensembl chr 3:10,285,666...10,292,947
JBrowse link
G GLO1 glyoxalase I severity IAGP
IEA
DNA:SNP: :419C>A (human) MouseDO
RGD
PMID:20185929 RGD:7242570 NCBI chr 6:38,675,925...38,703,145
Ensembl chr 6:38,675,925...38,703,145
JBrowse link
G GSR glutathione-disulfide reductase IEP protein:increased activity:blood:
protein:increased activity:lymphocyte:
RGD PMID:20181004 PMID:6463365 RGD:7257547, RGD:7257560 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
JBrowse link
G GSTM1 glutathione S-transferase mu 1 IAGP
IEA
MouseDO
RGD
PMID:24339523 RGD:14700960 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039
JBrowse link
G GSTT1 glutathione S-transferase theta 1 susceptibility IAGP
IEA
associated with Diabetes Mellitus;DNA:deletion MouseDO
RGD
PMID:15492856 RGD:2306631
G GTPBP4 GTP binding protein 4 ISO RGD PMID:11316846 RGD:632611 NCBI chr10:988,434...1,019,932
Ensembl chr10:988,434...1,019,932
JBrowse link
G GUCA2B guanylate cyclase activator 2B EXP CTD Direct Evidence: marker/mechanism CTD PMID:15780094 NCBI chr 1:42,153,410...42,155,820
Ensembl chr 1:42,153,410...42,155,820
JBrowse link
G HAMP hepcidin antimicrobial peptide ISO
EXP
IEP
mRNA:increased expression:liver
CTD Direct Evidence: marker/mechanism
protein:increased expression:plasma
CTD
RGD
PMID:16929540 PMID:20631677 PMID:19212416 RGD:11041611, RGD:11041622 NCBI chr19:35,282,528...35,285,143
Ensembl chr19:35,280,716...35,285,143
JBrowse link
G HBEGF heparin binding EGF like growth factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:21937979 NCBI chr 5:140,332,843...140,346,603
Ensembl chr 5:140,332,843...140,346,603
JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase ISO
EXP
associated with Hypertension
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:19878707 PMID:21119529 RGD:5508686 NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001
JBrowse link
G HMOX1 heme oxygenase 1 EXP CTD Direct Evidence: therapeutic CTD PMID:22622455 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO protein:increased expression:kidney (rat) RGD PMID:20820841 RGD:4145364 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
JBrowse link
G IGF1 insulin like growth factor 1 EXP CTD Direct Evidence: therapeutic CTD PMID:10198369 NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744
JBrowse link
G IL1A interleukin 1 alpha no_association IAGP
IEA
DNA:SNP
DNA:SNPs, deletion, haplotypes:3' utr:multiple (human)
DNA:SNP, insertion/deletion:intron, 3' utr:rs1516792-3, rs16347-2 (human)
MouseDO
RGD
PMID:20551628 PMID:12631337 PMID:12837270 RGD:6907070, RGD:6907106, RGD:6907105 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
JBrowse link
G IL1B interleukin 1 beta no_association IAGP
ISO
DNA:SNP
protein:increased expression:plasma (rat)
RGD PMID:20551628 PMID:20199183 PMID:22031851 RGD:6907070, RGD:7175346, RGD:7175302 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL1RN interleukin 1 receptor antagonist disease_progression
susceptibility
IAGP
IEA
IEP
DNA:repeats:intron:IVS2+914_1000dup IL1RN*2 (human)
DNA:repeats:intron:IVS2+914_1000dup IL1RN*1 (human)
protein:increased expression:serum (human)
DNA:polymorphism:exon:g.14709C>T rs315952 (human)
DNA:polymorphism:intron:IVS6+327A>G rs452204 (human)
MouseDO
RGD
PMID:17224277 PMID:16766392 PMID:16556139 PMID:12837270 PMID:20551628 RGD:6907131, RGD:6907370, RGD:6907368, RGD:6907105, RGD:6907070 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016
JBrowse link
G IL20 interleukin 20 IEP protein:increased expression:serum RGD PMID:18639518 RGD:5147394 NCBI chr 1:206,863,565...206,869,223
Ensembl chr 1:206,865,623...206,869,223
JBrowse link
G IL6 interleukin 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19539174 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G IRS1 insulin receptor substrate 1 ISO protein:decreased tyrosine phosphorylation:aorta RGD PMID:22942179 RGD:7207055 NCBI chr 2:226,731,312...226,799,820
Ensembl chr 2:226,731,312...226,799,820
JBrowse link
G ITGA8 integrin subunit alpha 8 IAGP
IEA
associated with Polycystic Kidney, Autosomal Dominant;DNA:polymorphism: :-414T>C(human) MouseDO
RGD
PMID:18277079 RGD:7257723 NCBI chr10:15,513,954...15,719,922
Ensembl chr10:15,513,954...15,719,922
JBrowse link
G ITGB3 integrin subunit beta 3 IAGP
IEA
associated with Hypertension;DNA:polymorphism MouseDO
RGD
PMID:19368146 RGD:6907396 NCBI chr17:47,253,827...47,313,743
Ensembl chr17:47,253,827...47,313,743
JBrowse link
G KEAP1 kelch like ECH associated protein 1 ISO protein:increased expression:renal cortex, cytosol (rat) RGD PMID:20007347 RGD:6892947 NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558
JBrowse link
G KL klotho IEP
ISO
mRNA,protein:decreased expression:kidney:
mRNA:decreased expression:kidney:
RGD PMID:11162628 PMID:9731228 RGD:10403042, RGD:10403067 NCBI chr13:33,016,243...33,066,143
Ensembl chr13:33,016,423...33,066,143
JBrowse link
G KLK1 kallikrein 1 IAGP
IEA
MouseDO
RGD
PMID:11849458 RGD:1581753 NCBI chr19:50,819,146...50,823,787
Ensembl chr19:50,819,146...50,823,787
JBrowse link
G LCAT lecithin-cholesterol acyltransferase ISO RGD PMID:15280162 RGD:1581769 NCBI chr16:67,939,750...67,944,120
Ensembl chr16:67,939,750...67,944,131
JBrowse link
G LCN2 lipocalin 2 onset IEP protein:increased expression:urine: RGD PMID:22542304 RGD:7245503 NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453
JBrowse link
G LEP leptin IEP protein:increased expression:serum (human) RGD PMID:9294834 RGD:10053636 NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629
JBrowse link
G LIPC lipase C, hepatic type ISO protein, mRNA:decreased expression:hepatocytes, liver (rat) RGD PMID:8636395 RGD:2308788 NCBI chr15:58,410,554...58,569,844
Ensembl chr15:58,410,569...58,569,844
JBrowse link
G LIPJ lipase family member J IAGP ClinVar Annotator: match by term: Stage 5 chronic kidney disease ClinVar PMID:28492532 NCBI chr10:88,582,907...88,623,184
Ensembl chr10:88,586,753...88,606,976
JBrowse link
G LPIN1 lipin 1 ISO mRNA:increased expression:skeletal muscle RGD PMID:14718385 RGD:1641826 NCBI chr 2:11,677,544...11,827,409
Ensembl chr 2:11,677,595...11,827,409
JBrowse link
G LPL lipoprotein lipase ISO RGD PMID:22009636 RGD:6909179 NCBI chr 8:19,939,253...19,967,259
Ensembl chr 8:19,901,717...19,967,259
JBrowse link
G LRP2 LDL receptor related protein 2 ISO mRNA:decreased expression:kidney RGD PMID:15266031 RGD:1641836 NCBI chr 2:169,127,109...169,362,534
Ensembl chr 2:169,127,109...169,362,534
JBrowse link
G MBL2 mannose binding lectin 2 IAGP
IEA
associated with Lupus Erythematosus, Systemic;DNA:polymorphisms MouseDO
RGD
PMID:16801331 RGD:6903261 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784
JBrowse link
G MLXIPL MLX interacting protein like EXP CTD Direct Evidence: marker/mechanism CTD PMID:19878707 NCBI chr 7:73,593,202...73,647,907
Ensembl chr 7:73,593,194...73,624,543
JBrowse link
G MMP1 matrix metallopeptidase 1 severity
no_association
IAGP
IEA
DNA:insertion, haplotype:promoter:g.-1607insG (human)
DNA:insertion:promoter:g.-1607insG (human)
MouseDO
RGD
PMID:19221176 PMID:22401717 RGD:7207064, RGD:7206856 NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160
JBrowse link
G MMP10 matrix metallopeptidase 10 IEP associated with Hypertension; protein:increased expression:plasma (human) RGD PMID:19886850 RGD:7207051 NCBI chr11:102,770,502...102,780,628
Ensembl chr11:102,770,502...102,780,628
JBrowse link
G MMP2 matrix metallopeptidase 2 IEP associated with Hypertension; protein:increased expression:plasma (human) RGD PMID:19886850 RGD:7207051 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
JBrowse link
G MMP3 matrix metallopeptidase 3 severity IAGP
IEA
DNA:insertion, haplotype:promoter:g.-1613insA (human) MouseDO
RGD
PMID:19221176 RGD:7207064 NCBI chr11:102,835,801...102,843,609
Ensembl chr11:102,835,801...102,843,609
JBrowse link
G MPO myeloperoxidase disease_progression IDA
IEA
MouseDO
RGD
PMID:20638167 RGD:6909184 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935
JBrowse link
G MSR1 macrophage scavenger receptor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19878707 NCBI chr 8:16,107,881...16,192,651
Ensembl chr 8:16,107,878...16,567,490
JBrowse link
G MTHFR methylenetetrahydrofolate reductase susceptibility
severity
no_association
IAGP
IEA
DNA:transition, transversion:cds:g.677C>T, g.1298A>C (human)
DNA:SNP: :677C>T(human)
DNA:transitions, transversion, haplotype:cds:g.677C>T, g.1298A>C, g.1793G>A (human)
associated with Diabetes Mellitus, Type 2; DNA:transition:cds:g.677C>T (human)
MouseDO
RGD
PMID:19520684 PMID:25664255 PMID:17899317 PMID:14737040 PMID:19520069 RGD:6893522, RGD:14696732, RGD:6893579, RGD:6893524, RGD:6893523 NCBI chr 1:11,785,723...11,805,964
Ensembl chr 1:11,785,723...11,806,455
JBrowse link
G MTOR mechanistic target of rapamycin kinase treatment ISO RGD PMID:22427849 RGD:10040968 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556
JBrowse link
G MYH9 myosin heavy chain 9 IAGP
EXP
associated with hypertension, glomerulosclerosis, focal segmental;DNA:SNPs: :rs4821480, rs2032487, rs4821481(human)
CTD Direct Evidence: marker/mechanism
associated with diabetes mellitus, type 2;DNA:SNPs: :
DNA:SNPs:multiple:
associated with hypertension;DNA:polymorphisms:multiple:
associated with diabetes mellitus,type 2;DNA:SNPs: :
CTD
RGD
PMID:18794854 PMID:18794856 PMID:18794854 PMID:21968013 PMID:20144966 More... RGD:6903237, RGD:6903256, RGD:6903243, RGD:6903239, RGD:6903238 NCBI chr22:36,281,280...36,387,967
Ensembl chr22:36,281,280...36,388,010
JBrowse link
G NAT2 N-acetyltransferase 2 ISO mRNA,protein:decreased expression:liver: RGD PMID:20007296 RGD:11533637 NCBI chr 8:18,386,301...18,401,218
Ensembl chr 8:18,391,282...18,401,218
JBrowse link
G NCF1 neutrophil cytosolic factor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19420110 NCBI chr 7:74,774,011...74,789,315
Ensembl chr 7:74,774,011...74,789,315
JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19420110 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302
JBrowse link
G NGF nerve growth factor treatment IDA
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:24244623 PMID:19169037 RGD:7242783 NCBI chr 1:115,285,917...115,338,249
Ensembl chr 1:115,285,904...115,338,770
JBrowse link
G NOS1 nitric oxide synthase 1 treatment ISO protein:decreased expression:kidney cortex RGD PMID:17200156 PMID:23185775 RGD:1642147, RGD:7257669 NCBI chr12:117,208,142...117,361,626
Ensembl chr12:117,208,142...117,452,170
JBrowse link
G NOS3 nitric oxide synthase 3 susceptibility ISO
IEA
IAGP
protein:decreased expression:glomerulus
DNA:duplication, snp:intron, cds:g.IVS4?-?+27, p.E298D (human)
MouseDO
RGD
PMID:18089446 PMID:12701818 RGD:2292109, RGD:7777097 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
JBrowse link
G NOX4 NADPH oxidase 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19420110 NCBI chr11:89,324,353...89,589,557
Ensembl chr11:89,324,353...89,498,187
JBrowse link
G NPHS1 NPHS1 adhesion molecule, nephrin disease_progression ISO mRNA;increased expression:urine (rat) RGD PMID:19389856 RGD:38599006 NCBI chr19:35,862,915...35,869,357
Ensembl chr19:35,825,964...35,869,287
JBrowse link
G NPPB natriuretic peptide B IEP protein:increased expression:plasma: RGD PMID:7606877 RGD:7246912 NCBI chr 1:11,857,464...11,858,945
Ensembl chr 1:11,857,464...11,858,945
JBrowse link
G NPPC natriuretic peptide C IEP protein:increased expression:plasma
protein:increased expression:plasma (human)
RGD PMID:8117275 PMID:8743538 RGD:1642297, RGD:1580770 NCBI chr 2:231,921,809...231,926,396
Ensembl chr 2:231,921,809...231,926,396
JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 ISO RGD PMID:18591458 RGD:7174716 NCBI chr 5:143,277,931...143,435,512
Ensembl chr 5:143,277,931...143,435,512
JBrowse link
G OLR1 oxidized low density lipoprotein receptor 1 ISO mRNA, protein:increased expression:kidney (rat) RGD PMID:12661921 RGD:1580992 NCBI chr12:10,158,301...10,176,266
Ensembl chr12:10,158,301...10,172,138
JBrowse link
G PAX2 paired box 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16631587 NCBI chr10:100,735,396...100,829,944
Ensembl chr10:100,735,396...100,829,944
JBrowse link
G PGF placental growth factor ISO RGD PMID:16543713 RGD:1642390 NCBI chr14:74,941,830...74,955,764
Ensembl chr14:74,941,834...74,955,626
JBrowse link
G PKD1 polycystin 1, transient receptor potential channel interacting IAGP ClinVar Annotator: match by term: End-stage renal failure ClinVar PMID:25741868 NCBI chr16:2,088,708...2,135,898
Ensembl chr16:2,088,708...2,135,898
JBrowse link
G PLA2G7 phospholipase A2 group VII IEP plasma:increased expression:plasma RGD PMID:16421163 RGD:7248787 NCBI chr 6:46,704,201...46,735,721
Ensembl chr 6:46,704,201...46,735,693
JBrowse link
G PLAU plasminogen activator, urokinase treatment
severity
IEP
IEA
ISO
IDA
protein:increased expression, increased activity:kidney (rat)
protein:increased expression:plasma (human)
MouseDO
RGD
PMID:19926968 PMID:15506291 PMID:17869326 PMID:22683425 RGD:6483806, RGD:7241279, RGD:7241218, RGD:7241081 NCBI chr10:73,909,164...73,917,494
Ensembl chr10:73,909,177...73,917,496
JBrowse link
G PLAUR plasminogen activator, urokinase receptor IEP RGD PMID:19926968 RGD:6483806 NCBI chr19:43,646,095...43,670,169
Ensembl chr19:43,646,095...43,670,547
JBrowse link
G POSTN periostin ISO mRNA,protein:increased expression,increased secretion:kidney,urine: RGD PMID:22167593 RGD:10040972 NCBI chr13:37,562,585...37,598,768
Ensembl chr13:37,562,583...37,598,844
JBrowse link
G PPARA peroxisome proliferator activated receptor alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:19878707 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma disease_progression IAGP
IEA
associated with Diabetes Mellitus, Insulin-Dependent;DNA:SNP: :p.P12A (human) MouseDO
RGD
PMID:18467141 RGD:2301857 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
JBrowse link
G PTGER4 prostaglandin E receptor 4 treatment ISO RGD PMID:16871242 RGD:10003092 NCBI chr 5:40,679,915...40,746,800
Ensembl chr 5:40,679,915...40,693,735
JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19420110 NCBI chr 9:122,370,533...122,395,703
Ensembl chr 9:122,370,530...122,395,703
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19420110 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G PTH parathyroid hormone severity ISO
IEP
protein:increased expression:serum (rat)
protein:increased expression:serum (human)
RGD PMID:23548814 PMID:23243213 RGD:7242564, RGD:7242692 NCBI chr11:13,492,054...13,496,181
Ensembl chr11:13,492,054...13,496,181
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit ISO
EXP
protein:increased expression:kidney
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:19420110 PMID:18077597 RGD:2298859 NCBI chr11:65,653,601...65,662,916
Ensembl chr11:65,653,599...65,663,090
JBrowse link
G RETN resistin severity IEP
EXP
protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:19539174 PMID:22421264 RGD:7207074 NCBI chr19:7,669,049...7,670,455
Ensembl chr19:7,669,049...7,670,455
JBrowse link
G RNLS renalase, FAD dependent amine oxidase IEP
IAGP
protein:decreased expression:plasma:
ClinVar Annotator: match by term: Stage 5 chronic kidney disease
ClinVar
RGD
PMID:28492532 PMID:15841207 RGD:7327153 NCBI chr10:88,171,523...88,583,318
Ensembl chr10:88,273,864...88,584,530
JBrowse link
G SCARB1 scavenger receptor class B member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19878707 NCBI chr12:124,776,856...124,863,864
Ensembl chr12:124,776,856...124,882,668
JBrowse link
G SELL selectin L no_association IAGP RGD PMID:22119815 RGD:7175303 NCBI chr 1:169,690,667...169,711,620
Ensembl chr 1:169,690,665...169,711,702
JBrowse link
G SERPINE1 serpin family E member 1 treatment ISO
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:19420110 PMID:26903149 RGD:11073683 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
JBrowse link
G SLC22A2 solute carrier family 22 member 2 ISO protein:decreased expression:kidney, plasma membrane RGD PMID:23280877 PMID:12110012 RGD:7243177, RGD:7243883 NCBI chr 6:160,216,755...160,258,821
Ensembl chr 6:160,171,061...160,277,638
JBrowse link
G SLC34A1 solute carrier family 34 member 1 ISO mRNA:decreased expression:renal cortex (rat) RGD PMID:15452708 RGD:7242930 NCBI chr 5:177,384,434...177,412,021
Ensembl chr 5:177,379,235...177,398,848
JBrowse link
G SLC9A5 solute carrier family 9 member A5 resistance IAGP
IEA
DNA:polymorphism MouseDO
RGD
PMID:10642288 RGD:1643221 NCBI chr16:67,248,979...67,272,191
Ensembl chr16:67,237,683...67,272,191
JBrowse link
G SOAT2 sterol O-acyltransferase 2 ISO RGD PMID:12217884 RGD:625687 NCBI chr12:53,103,486...53,124,535
Ensembl chr12:53,103,486...53,124,535
JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19878707 NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002
JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 ISO
EXP
mRNA, protein:increased expression:liver
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:19878707 PMID:16814791 RGD:2308825 NCBI chr22:41,833,105...41,907,305
Ensembl chr22:41,833,079...41,907,307
JBrowse link
G TBX21 T-box transcription factor 21 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26970513 NCBI chr17:47,733,236...47,746,122
Ensembl chr17:47,733,236...47,746,122
JBrowse link
G TGFB1 transforming growth factor beta 1 ISO
EXP
mRNA, protein:increased expression:kidney
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:19420110 PMID:10919844 RGD:7394838 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
G THBD thrombomodulin ISO
IEP
protein:increased expression:plasma RGD PMID:22129968 PMID:21873362 RGD:5684979, RGD:5684981 NCBI chr20:23,045,633...23,049,672
Ensembl chr20:23,045,633...23,049,672
JBrowse link
G TLR2 toll like receptor 2 IEP RGD PMID:20729266 RGD:7240546 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,070...153,706,260
JBrowse link
G TLR4 toll like receptor 4 IEP RGD PMID:20729266 RGD:7240546 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735
JBrowse link
G TNF tumor necrosis factor IEP
EXP
associated with Diabetes Mellitus, Type 2;protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:19539174 PMID:22266663 RGD:7245510 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TNFRSF11B TNF receptor superfamily member 11b severity IEP RGD PMID:21479768 RGD:7205485 NCBI chr 8:118,923,557...118,951,885
Ensembl chr 8:118,923,557...118,951,885
JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A IEP associated with Diabetes Mellitus, Type 2;protein:increased expression:plasma RGD PMID:22266663 RGD:7245510 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114
JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B IEP associated with Diabetes Mellitus, Type 2;protein:increased expression:plasma RGD PMID:22266663 RGD:7245510 NCBI chr 1:12,166,991...12,209,220
Ensembl chr 1:12,166,991...12,209,228
JBrowse link
G UCP2 uncoupling protein 2 susceptibility IAGP
IEA
DNA:polymorphism: :-866G>A (human)
DNA:deletion
MouseDO
RGD
PMID:19406964 PMID:18242170 RGD:7175298, RGD:7175299 NCBI chr11:73,974,672...73,983,202
Ensembl chr11:73,974,672...73,982,843
JBrowse link
G VWF von Willebrand factor disease_progression
treatment
IDA
IEA
IEP
protein:increased oxidation:plasma MouseDO
RGD
PMID:22189209 PMID:21378155 PMID:22091998 RGD:7205641, RGD:7205649, RGD:7205646 NCBI chr12:5,948,877...6,124,670
Ensembl chr12:5,948,877...6,124,770
JBrowse link
Frasier syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC107982234 WT1/WT1-AS bi-directional promoter region IAGP ClinVar Annotator: match by term: Frasier syndrome ClinVar PMID:15266301 PMID:18559874 PMID:18591546 PMID:19171881 PMID:19221039 More... NCBI chr11:32,430,848...32,437,423 JBrowse link
G WT1 WT1 transcription factor IAGP ClinVar Annotator: match by term: Frasier syndrome ClinVar
OMIM
PMID:1302008 PMID:1658787 PMID:7795587 PMID:8388765 PMID:9108089 More... NCBI chr11:32,387,775...32,435,539
Ensembl chr11:32,387,775...32,435,564
JBrowse link
hemolytic-uremic syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALB albumin EXP CTD Direct Evidence: marker/mechanism CTD PMID:6734075 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482
JBrowse link
G CCL2 C-C motif chemokine ligand 2 ISO protein:increased expression:plasma (rat) RGD PMID:10201001 RGD:11528527 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
JBrowse link
G CCL3 C-C motif chemokine ligand 3 ISO RGD PMID:17220320 RGD:7241820 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169
JBrowse link
G CD36 CD36 molecule IDA
IEA
MouseDO
RGD
PMID:16197457 RGD:6893534 NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277
JBrowse link
G CD46 CD46 molecule susceptibility IAGP
IEA
DNA:frameshift mutation:cds:p.N233X3 (human)
DNA:mutations:multiple (human)
DNA:deletion, missense mutation:cds:p.D237_S238del, p.S206P (human)
MouseDO
RGD
PMID:14615110 PMID:16189652 PMID:14566051 RGD:11352767, RGD:11531138, RGD:11352770 NCBI chr 1:207,752,038...207,795,516
Ensembl chr 1:207,752,037...207,795,513
JBrowse link
G CFH complement factor H IAGP
IEA
ISS
DNA:mutations, polymorphisms:promoter, exon:multiple
OMIM:235400 | OMIM:612922 | OMIM:612923 | OMIM:612924 | OMIM:612925 | OMIM:612926
MouseDO
RGD
PMID:14583443 RGD:11041164 NCBI chr 1:196,652,043...196,747,504
Ensembl chr 1:196,651,754...196,752,476
JBrowse link
G DGKE diacylglycerol kinase epsilon IAGP ClinVar Annotator: match by term: Hemolytic-uremic syndrome ClinVar PMID:25854283 NCBI chr17:56,834,151...56,869,567
Ensembl chr17:56,834,107...56,869,567
JBrowse link
G EPO erythropoietin EXP CTD Direct Evidence: therapeutic CTD PMID:12053072 NCBI chr 7:100,720,468...100,723,700
Ensembl chr 7:100,720,468...100,723,700
JBrowse link
G F2 coagulation factor II, thrombin IEP associated with diarrhea;protein:increased expression:plasma (human) RGD PMID:9423793 RGD:40818428 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit ISO RGD PMID:15632024 RGD:7242276 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
JBrowse link
G HP haptoglobin IEP RGD PMID:6218601 RGD:1626361 NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055
JBrowse link
G IL1A interleukin 1 alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:15384034 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
JBrowse link
G IL1B interleukin 1 beta EXP CTD Direct Evidence: marker/mechanism CTD PMID:15384034 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL1RL1 interleukin 1 receptor like 1 severity IEP associated with Escherichia Coli Infections; RGD PMID:30467800 RGD:39458200 NCBI chr 2:102,311,563...102,352,356
Ensembl chr 2:102,311,502...102,352,037
JBrowse link
G IL1RN interleukin 1 receptor antagonist IEP
IEA
IDA
protein:increased concentration:serum (human) MouseDO
RGD
PMID:9802632 PMID:12373296 RGD:6909134, RGD:6909171 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016
JBrowse link
G IL6 interleukin 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15384034 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G MBL2 mannose binding lectin 2 treatment IMP
IEA
MouseDO
RGD
PMID:27378476 RGD:11530050 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:12588957 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
JBrowse link
G PLA2G7 phospholipase A2 group VII severity IAGP
IEA
associated with Escherichia coli Infections; DNA:transversion mutation: :994 G>T (human) MouseDO
RGD
PMID:10873870 RGD:7257516 NCBI chr 6:46,704,201...46,735,721
Ensembl chr 6:46,704,201...46,735,693
JBrowse link
G PLAT plasminogen activator, tissue type IEP associated with Escherichia coli Infections;protein:increased expression:plasma (human) RGD PMID:11777999 RGD:11541069 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709
JBrowse link
G THBD thrombomodulin ISO RGD PMID:22942429 RGD:11038690 NCBI chr20:23,045,633...23,049,672
Ensembl chr20:23,045,633...23,049,672
JBrowse link
G TNF tumor necrosis factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:15384034 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
hepatorenal syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EDN1 endothelin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:7967349 NCBI chr 6:12,256,484...12,297,194
Ensembl chr 6:12,290,361...12,297,194
JBrowse link
G HMOX1 heme oxygenase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21253390 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G SOD1 superoxide dismutase 1 ISO RGD PMID:15531919 RGD:1581228 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
JBrowse link
G TLR4 toll like receptor 4 ISO mRNA, protein:increased expression:kidney RGD PMID:18093430 RGD:4144102 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735
JBrowse link
G TNF tumor necrosis factor ISO protein:increased expression:plasma RGD PMID:18093430 RGD:4144102 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
HUPRA Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SARS2 seryl-tRNA synthetase 2, mitochondrial IAGP ClinVar Annotator: match by term: HYPERURICEMIA, PULMONARY HYPERTENSION, RENAL FAILURE, AND ALKALOSIS SYNDROME
ClinVar Annotator: match by term: HUPRA SYNDROME
DNA:missense mutation:CDS:p.D390G (human)
ClinVar
OMIM
RGD
PMID:9536098 PMID:17576681 PMID:21255763 PMID:24034276 PMID:25741868 More... RGD:41410777 NCBI chr19:38,915,266...38,930,763
Ensembl chr19:38,915,266...38,930,763
JBrowse link
Kidney Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme ISO RGD PMID:21680852 RGD:6893484 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380
JBrowse link
G ACE2 angiotensin converting enzyme 2 ISO mRNA:decreased expression:kidney RGD PMID:20528771 RGD:9685432 NCBI chr  X:15,518,197...15,607,211
Ensembl chr  X:15,494,566...15,607,236
JBrowse link
G ADAM17 ADAM metallopeptidase domain 17 treatment ISO RGD PMID:22015440 RGD:13703100 NCBI chr 2:9,488,486...9,555,830
Ensembl chr 2:9,488,486...9,556,732
JBrowse link
G ADAM2 ADAM metallopeptidase domain 2 ISO RGD PMID:11967014 RGD:10047130 NCBI chr 8:39,743,735...39,838,227
Ensembl chr 8:39,743,735...39,838,227
JBrowse link
G ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif 1 ISO RGD PMID:18272597 RGD:9684850 NCBI chr21:26,835,755...26,845,409
Ensembl chr21:26,835,755...26,845,409
JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing treatment IDA RGD PMID:21412771 RGD:8695946 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463
JBrowse link
G ADM adrenomedullin treatment ISO
IDA
protein:increased expression:serum: RGD PMID:20538296 PMID:20538296 RGD:7364948, RGD:7364948 NCBI chr11:10,305,073...10,307,397
Ensembl chr11:10,305,073...10,307,397
JBrowse link
G AKR1A1 aldo-keto reductase family 1 member A1 ISO RGD PMID:31089212 RGD:27226686 NCBI chr 1:45,550,826...45,570,049
Ensembl chr 1:45,550,543...45,570,049
JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member ISO RGD PMID:22022451 RGD:7241603 NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532
JBrowse link
G ANXA1 annexin A1 treatment ISO RGD PMID:20953576 RGD:7421585 NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,393
JBrowse link
G ANXA5 annexin A5 IDA RGD PMID:21918686 RGD:7242028 NCBI chr 4:121,667,946...121,696,980
Ensembl chr 4:121,667,946...121,696,995
JBrowse link
G APAF1 apoptotic peptidase activating factor 1 treatment ISO RGD PMID:26362957 RGD:13703110 NCBI chr12:98,645,290...98,735,433
Ensembl chr12:98,645,290...98,735,433
JBrowse link
G APOA1 apolipoprotein A1 treatment IDA RGD PMID:18535924 RGD:7241574 NCBI chr11:116,835,751...116,837,950
Ensembl chr11:116,835,751...116,837,622
JBrowse link
G