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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:separation anxiety disorder
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Accession:DOID:10685 term browser browse the term
Definition:An anxiety disorder that involves the feeling of excessive and inappropriate levels of anxiety over being separated from a person to whom the individual has a strong emotional attachment or place. (DO)
Synonyms:exact_synonym: separation anxiety
 primary_id: MESH:D001010
 xref: EFO:1001916
For additional species annotation, visit the Alliance of Genome Resources.


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separation anxiety disorder term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DRD4 dopamine receptor D4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20731709 NCBI chr11:640,401...646,775 JBrowse link
G NGF nerve growth factor ISO protein:decreased expression:hippocampus RGD PMID:24407463 RGD:401976437 NCBI chr 1:87,223,597...87,276,759 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17996
    Developmental Disease 17885
      Neurodevelopmental Disorders 6850
        separation anxiety disorder 2
Path 2
Term Annotations click to browse term
  disease 17996
    disease of anatomical entity 15260
      nervous system disease 13293
        central nervous system disease 11923
          brain disease 11204
            disease of mental health 8111
              cognitive disorder 2153
                anxiety disorder 115
                  separation anxiety disorder 2
paths to the root