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ONTOLOGY REPORT - ANNOTATIONS


Term:pneumoconiosis
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Accession:DOID:10316 term browser browse the term
Definition:A diffuse parenchymal lung disease caused by inhalation of dust and by tissue reaction to its presence. These inorganic, organic, particulate, or vaporized matters usually are inhaled by workers in their occupational environment, leading to the various forms (ASBESTOSIS; BYSSINOSIS; and others). Similar air pollution can also have deleterious effects on the general population.
Synonyms:exact_synonym: Pneumoconioses
 primary_id: MESH:D011009
 alt_id: RDO:0002853
 xref: ICD10CM:J64;   ICD9CM:505;   NCI:C26861
For additional species annotation, visit the Alliance of Genome Resources.


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pneumoconiosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acan aggrecan JBrowse link 1 140,762,758 140,824,441 RGD:11554173
G Atr ATR serine/threonine kinase JBrowse link 8 103,673,578 103,770,886 RGD:11554173
G Ca3 carbonic anhydrase 3 JBrowse link 2 88,126,519 88,136,063 RGD:11554173
G Car1 carbonic anhydrase 1 JBrowse link 2 88,185,204 88,227,486 RGD:11554173
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:5130756
G Cdh23 cadherin-related 23 JBrowse link 20 29,857,018 30,263,758 RGD:11554173
G H3f4 H3.4 histone JBrowse link 10 45,304,696 45,305,106 RGD:11554173
G Hs3st6 heparan sulfate-glucosamine 3-sulfotransferase 6 JBrowse link 10 14,122,856 14,128,984 RGD:11554173
G Il27ra interleukin 27 receptor subunit alpha JBrowse link 19 25,151,835 25,163,995 RGD:11554173
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:11554173
G Mdm4 MDM4 regulator of p53 JBrowse link 13 49,786,776 49,828,780 RGD:11554173
G Ptprz1 protein tyrosine phosphatase, receptor type Z1 JBrowse link 4 49,941,046 50,140,764 RGD:11554173
G RT1-Bb RT1 class II, locus Bb JBrowse link 20 4,043,726 4,049,367 RGD:7421557
G Ticam1 toll-like receptor adaptor molecule 1 JBrowse link 9 10,780,185 10,790,280 RGD:11554173
G Tmprss3 transmembrane serine protease 3 JBrowse link 20 9,910,522 9,929,705 RGD:11554173
anthracosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp1a4 ATPase Na+/K+ transporting subunit alpha 4 JBrowse link 13 90,605,792 90,642,032 RGD:11554173
G Flacc1 flagellum associated containing coiled-coil domains 1 JBrowse link 9 65,665,663 65,693,822 RGD:11554173
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:11554173
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:11554173
G Il1rn interleukin 1 receptor antagonist JBrowse link 3 1,449,778 1,468,624 RGD:11554173
G Rbm26 RNA binding motif protein 26 JBrowse link 15 89,262,683 89,339,323 RGD:11554173
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:11554173
asbestosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arg1 arginase 1 JBrowse link 1 21,525,421 21,537,872 RGD:11554173
G Atf6 activating transcription factor 6 JBrowse link 13 89,053,457 89,242,531 RGD:11554173
G Cfd complement factor D JBrowse link 7 12,634,216 12,635,939 RGD:11554173
G Clca1 chloride channel accessory 1 JBrowse link 2 250,897,980 250,923,711 RGD:4145655
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 JBrowse link 1 213,511,892 213,522,195 RGD:4892076
G Ddit3 DNA-damage inducible transcript 3 JBrowse link 7 70,578,564 70,585,074 RGD:11554173
G Ephx1 epoxide hydrolase 1 JBrowse link 13 99,271,390 99,300,580 RGD:4889408
G Gstm1 glutathione S-transferase mu 1 JBrowse link 2 210,803,869 210,809,461 RGD:5490588
G Gstt1 glutathione S-transferase theta 1 JBrowse link 20 13,799,102 13,816,527 RGD:11554173
G Hspa5 heat shock protein family A (Hsp70) member 5 JBrowse link 3 13,838,304 13,842,763 RGD:11554173
G Nlrp3 NLR family, pyrin domain containing 3 JBrowse link 10 45,884,324 45,918,290 RGD:11554173
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:4891441
RGD:11554173
RGD:4891438
G Prdx1 peroxiredoxin 1 JBrowse link 5 135,536,413 135,551,986 RGD:11554173
G Prdx2 peroxiredoxin 2 JBrowse link 19 26,084,816 26,090,095 RGD:11554173
G Serpina1 serpin family A member 1 JBrowse link 6 127,610,241 127,632,265 RGD:11554173
G Spp1 secreted phosphoprotein 1 JBrowse link 14 6,673,686 6,679,965 RGD:11554173
G Tnc tenascin C JBrowse link 5 79,789,686 79,874,555 RGD:4889594
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:11554173
G Tpm4 tropomyosin 4 JBrowse link 16 19,385,810 19,399,851 RGD:11554173
berylliosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ace angiotensin I converting enzyme JBrowse link 10 94,170,766 94,213,831 RGD:11554173
G Btnl2 butyrophilin-like 2 JBrowse link 20 4,140,184 4,156,365 RGD:9685029
RGD:11554173
G Ccr5 C-C motif chemokine receptor 5 JBrowse link 8 133,192,398 133,215,599 RGD:4892065
G Cd28 Cd28 molecule JBrowse link 9 67,546,408 67,573,858 RGD:11554173
G Gclm glutamate cysteine ligase, modifier subunit JBrowse link 2 225,827,504 225,847,876 RGD:11554173
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:4145349
G Il2ra interleukin 2 receptor subunit alpha JBrowse link 17 70,500,672 70,547,929 RGD:11554173
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:11554173
G RT1-Db1 RT1 class II, locus Db1 JBrowse link 20 4,087,621 4,097,190 RGD:11554173
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:4145294
RGD:11554173
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:11554173
silicosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ahr aryl hydrocarbon receptor JBrowse link 6 54,963,990 55,001,806 RGD:11554173
G Arg1 arginase 1 JBrowse link 1 21,525,421 21,537,872 RGD:4143368
RGD:11554173
G Arpc2 actin related protein 2/3 complex, subunit 2 JBrowse link 9 81,518,163 81,548,871 RGD:4893904
G C3 complement C3 JBrowse link 9 9,721,137 9,747,084 RGD:5129516
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:11554173
G Ccl7 C-C motif chemokine ligand 7 JBrowse link 10 69,423,083 69,424,933 RGD:6483764
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:11041147
G Chia chitinase, acidic JBrowse link 2 208,750,348 208,797,388 RGD:4893904
G Cpm carboxypeptidase M JBrowse link 7 60,654,350 60,714,620 RGD:11554173
G Csf2 colony stimulating factor 2 JBrowse link 10 39,602,089 39,604,070 RGD:10450467
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 JBrowse link 9 67,699,397 67,706,068 RGD:4891515
G Egr1 early growth response 1 JBrowse link 18 27,657,903 27,660,101 RGD:5131937
G Eln elastin JBrowse link 12 24,978,478 25,021,864 RGD:9585691
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:4145384
G Hnrnpa3 heterogeneous nuclear ribonucleoprotein A3 JBrowse link 3 62,481,222 62,491,356 RGD:10059658
G Il17a interleukin 17A JBrowse link 9 26,841,299 26,844,786 RGD:4888525
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:11554173
G Il1rn interleukin 1 receptor antagonist JBrowse link 3 1,449,778 1,468,624 RGD:4142816
RGD:8551847
G Il2ra interleukin 2 receptor subunit alpha JBrowse link 17 70,500,672 70,547,929 RGD:4891500
G Jun Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 5 114,011,184 114,014,277 RGD:11554173
G Mmp13 matrix metallopeptidase 13 JBrowse link 8 5,522,739 5,533,018 RGD:10043156
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:4891445
RGD:11554173
G Pdzrn4 PDZ domain containing RING finger 4 JBrowse link 7 133,856,101 134,004,250 RGD:11554173
G Prkcb protein kinase C, beta JBrowse link 1 192,233,569 192,575,339 RGD:1625527
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:11554173
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:4142816
RGD:10450591
G Tnfrsf1a TNF receptor superfamily member 1A JBrowse link 4 157,864,905 157,877,634 RGD:5131150

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15502
    Occupational Diseases 111
      pneumoconiosis 70
        Byssinosis + 0
        Caplan's syndrome 0
        anthracosilicosis 0
        anthracosis + 7
        asbestosis 19
        bagassosis 0
        baritosis 0
        berylliosis 11
        kaolin pneumoconiosis 0
        mixed mineral dust pneumoconiosis 0
        pneumoconiosis due to talc 0
        siderosis + 0
        silicosis + 27
        slate pneumoconiosis 0
Path 2
Term Annotations click to browse term
  disease 15502
    disease of anatomical entity 14856
      respiratory system disease 2409
        lower respiratory tract disease 1444
          lung disease 1403
            Lung Injury 235
              pneumoconiosis 70
                Byssinosis + 0
                Caplan's syndrome 0
                anthracosilicosis 0
                anthracosis + 7
                asbestosis 19
                bagassosis 0
                baritosis 0
                berylliosis 11
                kaolin pneumoconiosis 0
                mixed mineral dust pneumoconiosis 0
                pneumoconiosis due to talc 0
                siderosis + 0
                silicosis + 27
                slate pneumoconiosis 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.