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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:viral meningitis
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Accession:DOID:10310 term browser browse the term
Definition:Viral infections of the leptomeninges and subarachnoid space. TOGAVIRIDAE INFECTIONS; FLAVIVIRIDAE INFECTIONS; RUBELLA; BUNYAVIRIDAE INFECTIONS; ORBIVIRUS infections; PICORNAVIRIDAE INFECTIONS; ORTHOMYXOVIRIDAE INFECTIONS; RHABDOVIRIDAE INFECTIONS; ARENAVIRIDAE INFECTIONS; HERPESVIRIDAE INFECTIONS; ADENOVIRIDAE INFECTIONS; JC VIRUS infections; and RETROVIRIDAE INFECTIONS may cause this form of meningitis. Clinical manifestations include fever, headache, neck pain, vomiting, PHOTOPHOBIA, and signs of meningeal irritation. (From Joynt, Clinical Neurology, 1996, Ch26, pp1-3)
Synonyms:exact_synonym: viral meningitides
 primary_id: MESH:D008587
 xref: ICD10CM:A87;   ICD9CM:047.9;   NCI:C118298
For additional species annotation, visit the Alliance of Genome Resources.


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viral meningitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tlr4 toll-like receptor 4 ISO mRNA:increased expression: : RGD PMID:12781911 RGD:7794740 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
aseptic meningitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:5108595 PMID:5109917 PMID:5536438 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10888991 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
lymphocytic choriomeningitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd274 CD274 molecule ISO RGD PMID:23230000 RGD:41410802 NCBI chr 1:247,519,890...247,539,659
Ensembl chr 1:247,519,939...247,537,943
JBrowse link
G Clec12a C-type lectin domain family 12, member A disease_progression ISO RGD PMID:31451663 RGD:41412202 NCBI chr 4:163,112,100...163,130,979
Ensembl chr 4:163,112,301...163,126,864
JBrowse link
G Ifnar1 interferon alpha and beta receptor subunit 1 disease_progression ISO DNA:mutation: : RGD PMID:28878077, PMID:24760883 RGD:124715467, RGD:124715479 NCBI chr11:31,640,407...31,666,839
Ensembl chr11:31,640,407...31,664,061
JBrowse link
G Ifngr1 interferon gamma receptor 1 ameliorates ISO RGD PMID:22496215 RGD:124715469 NCBI chr 1:15,062,380...15,080,815
Ensembl chr 1:15,062,432...15,080,907
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 severity ISO RGD PMID:25829541 RGD:40400708 NCBI chr 9:47,133,483...47,184,316
Ensembl chr 9:47,134,034...47,182,170
JBrowse link
G Il21r interleukin 21 receptor ISO RGD PMID:19478140 RGD:6892934 NCBI chr 1:196,996,405...197,024,185
Ensembl chr 1:196,996,581...197,024,166
JBrowse link
G Irf7 interferon regulatory factor 7 disease_progression ISO RGD PMID:24760883, PMID:24760883 RGD:124715479, RGD:124715479 NCBI chr 1:214,249,388...214,252,909
Ensembl chr 1:214,248,837...214,252,456
JBrowse link
G Irf9 interferon regulatory factor 9 disease_progression
ameliorates
ISO DNA:mutation: : RGD PMID:28878077, PMID:24760883, PMID:22496215 RGD:124715467, RGD:124715479, RGD:124715469 NCBI chr15:34,282,936...34,288,981
Ensembl chr15:34,282,936...34,288,138
JBrowse link
G Ncr1 natural cytotoxicity triggering receptor 1 ISO RGD PMID:30995287 RGD:40818298 NCBI chr 1:73,178,917...73,226,504
Ensembl chr 1:73,179,013...73,226,777
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 severity ISO RGD PMID:20565293 RGD:40902858 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkb2 nuclear factor kappa B subunit 2 disease_progression ISO RGD PMID:20565293 RGD:40902858 NCBI chr 1:266,050,634...266,059,277
Ensembl chr 1:266,053,002...266,059,256
JBrowse link
G Pdcd1 programmed cell death 1 treatment ISO RGD PMID:30726291, PMID:23230000 RGD:40818232, RGD:41410802 NCBI chr 9:101,305,742...101,319,937
Ensembl chr 9:101,307,764...101,319,845
Ensembl chr 9:101,307,764...101,319,845
JBrowse link
G Stat1 signal transducer and activator of transcription 1 exacerbates ISO RGD PMID:22496215 RGD:124715469 NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533
JBrowse link
G Stat2 signal transducer and activator of transcription 2 ISO RGD PMID:32094187, PMID:24760883 RGD:42722006, RGD:124715479 NCBI chr 7:2,691,064...2,707,530
Ensembl chr 7:2,691,369...2,707,741
JBrowse link
G Was WASP actin nucleation promoting factor ISO RGD PMID:23141740 RGD:38676258 NCBI chr  X:15,155,246...15,164,099
Ensembl chr  X:15,155,230...15,164,105
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16918
    disease by infectious agent 1839
      viral infectious disease 1517
        Central Nervous System Viral Diseases 87
          viral meningitis 18
            aseptic meningitis 2
            lymphocytic choriomeningitis 15
Path 2
Term Annotations click to browse term
  disease 16918
    disease of anatomical entity 16286
      nervous system disease 11864
        central nervous system disease 10197
          Central Nervous System Infections 202
            Central Nervous System Viral Diseases 87
              viral meningitis 18
                aseptic meningitis 2
                lymphocytic choriomeningitis 15
paths to the root