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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:prostate carcinoma
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Accession:DOID:10286 term browser browse the term
Definition:A prostate cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells. (DO)
Synonyms:exact_synonym: cancer of prostate;   carcinoma of prostate
 narrow_synonym: metastatic prostate carcinoma
 xref: NCI:C128122;   NCI:C4863
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
 
prostate carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt2 AKT serine/threonine kinase 2 treatment ISO RGD PMID:24838891 RGD:13504674 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
JBrowse link
G Angpt1 angiopoietin 1 ISO protein:increased expression:prostate gland RGD PMID:11326698 RGD:1643336 NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067
JBrowse link
G Atf4 activating transcription factor 4 treatment ISO RGD PMID:25680860 RGD:13504680 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Bad BCL2-associated agonist of cell death ISO protein:increased expression:prostate gland RGD PMID:11781193 RGD:2292676 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bax BCL2 associated X, apoptosis regulator disease_progression ISO protein:increased expression:prostate gland epithelium RGD PMID:17454944 RGD:1643355 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2l1 Bcl2-like 1 ISO RGD PMID:17653717 RGD:1643474 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bcl2l14 BCL2 like 14 ISO mRNA:decreased expression:prostate gland RGD PMID:14999772 RGD:2315712 NCBI chr 4:167,217,561...167,258,723
Ensembl chr 4:167,219,871...167,258,086
JBrowse link
G Bmp2 bone morphogenetic protein 2 disease_progression ISO protein:increased expression:prostate gland RGD PMID:16519147 RGD:1643592 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
JBrowse link
G Bmp4 bone morphogenetic protein 4 disease_progression ISO protein:increased expression:prostate RGD PMID:16519147 RGD:1643592 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Casp6 caspase 6 IEP mRNA:increased expression:prostate gland RGD PMID:11406539 RGD:1582381 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
JBrowse link
G Cga glycoprotein hormones, alpha polypeptide ISO mRNA:increased expression:prostate gland RGD PMID:12180238 RGD:2293634 NCBI chr 5:49,486,915...49,499,192
Ensembl chr 5:49,487,068...49,499,191
JBrowse link
G Chi3l1 chitinase 3 like 1 severity ISO protein:increased secretion:serum (human) RGD PMID:16372331 RGD:4892641 NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787
JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein ISO protein:decreased tyrosine phosphorylation:prostate gland RGD PMID:16391854 RGD:7488899 NCBI chr11:83,528,788...83,563,214
Ensembl chr11:83,526,530...83,563,238
JBrowse link
G Eif3h eukaryotic translation initiation factor 3, subunit H ISO DNA:amplification RGD PMID:14997205 RGD:2289900 NCBI chr 7:83,091,045...83,174,436
Ensembl chr 7:83,091,039...83,174,451
JBrowse link
G Ghrh growth hormone releasing hormone ISO mRNA:increased expression:prostate RGD PMID:12364462 RGD:2289976 NCBI chr 3:145,992,762...146,012,528
Ensembl chr 3:145,992,763...146,011,889
JBrowse link
G Hdac2 histone deacetylase 2 disease_progression ISO protein:increased expression:prostate gland RGD PMID:18212746 RGD:2306214 NCBI chr20:40,548,250...40,571,609
Ensembl chr20:40,548,250...40,571,609
JBrowse link
G Hdac3 histone deacetylase 3 ISO protein:increased expression:prostate gland RGD PMID:18212746 RGD:2306214 NCBI chr18:29,770,637...29,789,850
Ensembl chr18:29,770,636...29,793,856
JBrowse link
G Hmbs hydroxymethylbilane synthase ISO mRNA:decreased expression:tumor:in matched malignant and non-malignant sample pairs (p = 0.009) (human) RGD PMID:16211407 RGD:2301682 NCBI chr 8:44,673,554...44,680,950
Ensembl chr 8:44,673,554...44,680,957
JBrowse link
G Igf1r insulin-like growth factor 1 receptor IEP RGD PMID:18079205 RGD:13504770 NCBI chr 1:121,549,839...121,838,545
Ensembl chr 1:121,550,743...121,831,777
JBrowse link
G Inha inhibin subunit alpha ISO RGD PMID:11818495 RGD:2290381 NCBI chr 9:76,994,465...76,997,366
Ensembl chr 9:76,993,589...76,997,248
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit ISO RGD PMID:16413376 RGD:2290480 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase disease_progression ISO protein:increased expression:primary tumor, metastatic carcinoma (human) RGD PMID:7639332 RGD:2317554 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876
JBrowse link
G Mgp matrix Gla protein ISO RGD PMID:1399132 RGD:2293578 NCBI chr 4:169,766,290...169,769,612
Ensembl chr 4:169,766,279...169,769,667
JBrowse link
G Mki67 marker of proliferation Ki-67 IDA RGD PMID:22268182 RGD:6483545 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mmp7 matrix metallopeptidase 7 IDA RGD PMID:11406539 RGD:1582381 NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902
JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 ISO RGD PMID:8618340 RGD:2299063 NCBI chr10:78,907,036...78,929,659
Ensembl chr10:78,906,083...78,916,408
JBrowse link
G Pdgfb platelet derived growth factor subunit B ISO RGD PMID:23297038 RGD:13506769 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
G Pdgfd platelet derived growth factor D disease_progression ISO RGD PMID:21098708 RGD:13506773 NCBI chr 8:3,488,448...3,722,395
Ensembl chr 8:3,488,423...3,722,395
JBrowse link
G Plk1 polo-like kinase 1 ISO mRNA, protein:increased expression:prostate gland RGD PMID:15948124 RGD:2299939 NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400
JBrowse link
G Prkca protein kinase C, alpha ISO RGD PMID:9474241 RGD:2292463 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
JBrowse link
G Sars1 seryl-tRNA synthetase 1 ISO mRNA:decreased expression:prostate gland (human) RGD PMID:26317032 RGD:41410436 NCBI chr 2:196,065,543...196,081,240
Ensembl chr 2:196,065,430...196,081,277
JBrowse link
G Skp2 S-phase kinase associated protein 2 ISO RGD PMID:12670908 RGD:2315046 NCBI chr 2:58,161,226...58,189,293
Ensembl chr 2:58,161,229...58,189,338
JBrowse link
G Spint1 serine peptidase inhibitor, Kunitz type 1 disease_progression ISO protein:decreased expression:prostate gland (human) RGD PMID:16492908 RGD:1581314 NCBI chr 3:106,231,082...106,244,121
Ensembl chr 3:106,231,444...106,244,119
JBrowse link
G Spp1 secreted phosphoprotein 1 ISO RGD PMID:16331611 RGD:1581362 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO protein:increased activity:prostate gland RGD PMID:11987152 PMID:18210874 RGD:2298538, RGD:2291910 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Stat6 signal transducer and activator of transcription 6 ISO RGD PMID:11912448 RGD:2298560 NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495
JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 ISO mRNA:increased expression:prostate gland RGD PMID:12875974 RGD:2291960 NCBI chr 7:130,512,428...130,543,637
Ensembl chr 7:130,527,316...130,543,633
JBrowse link
G Tp73 tumor protein p73 disease_progression ISO mRNA, protein:increased expression:prostate gland RGD PMID:16254107 RGD:2290587 NCBI chr 5:164,621,377...164,703,958
Ensembl chr 5:164,621,377...164,681,128
JBrowse link
castration-resistant prostate carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c3 aldo-keto reductase family 1, member C3 ISO mRNA,protein:increased expression:epithelial cell:
CTD Direct Evidence: marker/mechanism
CTD PMID:25555457 PMID:23196782 RGD:10053626 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
JBrowse link
G Ar androgen receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:18985049 PMID:24740322 PMID:28500234 PMID:28757136 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Asf1b anti-silencing function 1B histone chaperone ISO CTD Direct Evidence: marker/mechanism CTD PMID:29581250 NCBI chr19:24,181,024...24,195,604
Ensembl chr19:24,181,028...24,195,549
JBrowse link
G Ccne2 cyclin E2 treatment ISO RGD PMID:27431942 RGD:13504681 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
JBrowse link
G Cd46 CD46 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:30185663 NCBI chr13:106,575,586...106,606,325 JBrowse link
G Cenpk centromere protein K ISO CTD Direct Evidence: marker/mechanism CTD PMID:29581250 NCBI chr 2:35,360,132...35,421,372
Ensembl chr 2:35,360,132...35,385,706
JBrowse link
G Chd1 chromodomain helicase DNA binding protein 1 ISO DNA:mutations: : RGD PMID:22722839 RGD:9587749 NCBI chr 1:56,661,743...56,729,119
Ensembl chr 1:56,664,054...56,728,125
JBrowse link
G Kdm1a lysine demethylase 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:29581250 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319
JBrowse link
G Nuf2 NUF2 component of NDC80 kinetochore complex treatment ISO RGD PMID:28498618 RGD:28867238 NCBI chr13:81,693,675...81,722,765
Ensembl chr13:81,693,598...81,722,766
JBrowse link
G Trim24 tripartite motif-containing 24 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27238081 NCBI chr 4:66,664,864...66,717,244
Ensembl chr 4:66,566,686...66,717,241
JBrowse link
G Zfp217 zinc finger protein 217 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29581250 NCBI chr 3:158,890,464...158,931,148
Ensembl chr 3:158,892,265...158,913,040
JBrowse link
G Zfp367 zinc finger protein 367 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29581250 NCBI chr17:965,161...984,290
Ensembl chr17:965,161...984,287
JBrowse link
prostate adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing susceptibility ISO DNA:SNPs, haplotypes:5' utr, introns, exon:multiple RGD PMID:21397927 RGD:8694410 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Adipor1 adiponectin receptor 1 susceptibility ISO DNA:SNPs, haplotype:intron, exon: (rs12733285, rs7539452) (human) RGD PMID:21397927 RGD:8694410 NCBI chr13:45,859,461...45,879,248
Ensembl chr13:45,859,533...45,879,241
JBrowse link
G Akt1 AKT serine/threonine kinase 1 treatment ISO ClinVar Annotator: match by term: Adenocarcinoma of prostate ClinVar PMID:17611497 PMID:18256540 PMID:18392055 PMID:18504432 PMID:18611285 More... RGD:13504677 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Akt2 AKT serine/threonine kinase 2 treatment ISO RGD PMID:20638364 RGD:13504677 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
JBrowse link
G Akt3 AKT serine/threonine kinase 3 treatment ISO RGD PMID:20638364 RGD:13504677 NCBI chr13:88,943,708...89,225,831
Ensembl chr13:88,946,091...89,225,708
JBrowse link
G Ar androgen receptor treatment IDA RGD PMID:18439064 RGD:10043341 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Bin1 bridging integrator 1 ISO RGD PMID:12532338 RGD:1580047 NCBI chr18:24,009,731...24,067,267
Ensembl chr18:24,009,653...24,067,263
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Adenocarcinoma of prostate ClinVar PMID:2493360 PMID:12068308 PMID:12198537 PMID:12460918 PMID:12460919 More... RGD:2315868 NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
JBrowse link
G Camk2n1 calcium/calmodulin-dependent protein kinase II inhibitor 1 treatment ISO RGD PMID:25003983 RGD:18337280 NCBI chr 5:150,674,819...150,676,600
Ensembl chr 5:150,673,507...150,676,600
JBrowse link
G Ccnb1 cyclin B1 severity ISO RGD PMID:10193948 RGD:2315940 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccne2 cyclin E2 ISO RGD PMID:25315431 RGD:13504706 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
JBrowse link
G Cd9 CD9 molecule disease_progression ISO DNA, mRNA:deletion, point mutation, decreased expression:prostate gland RGD PMID:17406028 RGD:2326197 NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO ClinVar Annotator: match by term: Adenocarcinoma of prostate ClinVar PMID:25741868 PMID:26619011 PMID:28492532 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex treatment ISO RGD PMID:26379052 RGD:13504774 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
JBrowse link
G Clu clusterin treatment IEP RGD PMID:24118288 RGD:9068419 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Cnot9 CCR4-NOT transcription complex subunit 9 ISO ClinVar Annotator: match by term: Adenocarcinoma of prostate ClinVar PMID:26619011 NCBI chr 9:76,084,269...76,109,111
Ensembl chr 9:76,084,334...76,109,100
JBrowse link
G Creb3l4 cAMP responsive element binding protein 3-like 4 ISO RGD PMID:17270658 PMID:11830526 RGD:13504714, RGD:13504715 NCBI chr 2:175,690,340...175,696,084
Ensembl chr 2:175,690,335...175,695,932
JBrowse link
G Ctnnb1 catenin beta 1 ISO ClinVar Annotator: match by term: Adenocarcinoma of prostate ClinVar PMID:9065402 PMID:9065403 PMID:9294210 PMID:9500465 PMID:9927029 More... NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Dnmt1 DNA methyltransferase 1 ISO mRNA,protein:increased expression:prostate gland: RGD PMID:17178860 RGD:2289681 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha ISO mRNA:increased expression:prostate gland: RGD PMID:17178860 RGD:2289681 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta ISO mRNA,protein:increased expression:prostate gland: RGD PMID:17178860 RGD:2289681 NCBI chr 3:142,130,592...142,169,124
Ensembl chr 3:142,130,592...142,169,124
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO ClinVar Annotator: match by term: Adenocarcinoma of prostate ClinVar PMID:23220880 PMID:26619011 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G Fgf2 fibroblast growth factor 2 disease_progression ISO RGD PMID:14522896 RGD:2290290 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 ISO RGD PMID:23576558 PMID:18068632 RGD:13504748, RGD:2298702 NCBI chr16:66,492,445...66,546,731
Ensembl chr16:66,494,042...66,547,350
JBrowse link
G Grb2 growth factor receptor bound protein 2 ISO RGD PMID:26103942 RGD:11056009 NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309
JBrowse link
G Hras HRas proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Adenocarcinoma of prostate ClinVar PMID:1904555 PMID:3510078 PMID:11150980 PMID:16155195 PMID:16170316 More... NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 ISO ClinVar Annotator: match by term: Adenocarcinoma of prostate ClinVar PMID:18772396 PMID:19657110 PMID:19798509 PMID:19818334 PMID:20946881 More... NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708
JBrowse link
G Igf1r insulin-like growth factor 1 receptor treatment
disease_progression
ISO
IMP
RGD PMID:26452103 PMID:8692980 PMID:25442907 PMID:25862373 RGD:13504753, RGD:13504771, RGD:13504768, RGD:13504767 NCBI chr 1:121,549,839...121,838,545
Ensembl chr 1:121,550,743...121,831,777
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta treatment ISO RGD PMID:27196761 RGD:13504772 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
JBrowse link
G Ilk integrin-linked kinase disease_progression ISO protein:increased expression:tumor: high-grade tumors versus adjacent BHP (P<0.001), BHP from cancer-free patients (P<0.002), or low-grade tumors (P=0.003), also associated with proliferative index (P=0.001), but inversely related to 5-year survival (p=0.004) (human) RGD PMID:11448915 RGD:2301734 NCBI chr 1:160,088,839...160,095,140
Ensembl chr 1:160,088,897...160,095,140
JBrowse link
G Insr insulin receptor treatment ISO RGD PMID:26452103 RGD:13504753 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit disease_progression ISO RGD PMID:9748134 RGD:2290484 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kdr kinase insert domain receptor ISO
IEP
protein:increased expression:prostate gland RGD PMID:17491265 PMID:20808233 RGD:2291925, RGD:5684541 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Lrrc56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: Adenocarcinoma of prostate ClinVar PMID:1904555 PMID:3510078 PMID:11150980 PMID:16155195 PMID:16170316 More... NCBI chr 1:196,299,843...196,315,170
Ensembl chr 1:196,299,846...196,315,172
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 disease_progression IDA
ISO
metastasis; inhibition reduced invasiveness of prostate tumor cells
ClinVar Annotator: match by term: Adenocarcinoma of prostate
ClinVar PMID:23444215 PMID:25157968 PMID:26619011 PMID:12688676 RGD:2292631 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Mapk1 mitogen activated protein kinase 1 treatment ISO RGD PMID:28492138 PMID:22139534 RGD:13504818, RGD:13504820 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Med12 mediator complex subunit 12 ISO ClinVar Annotator: match by term: Adenocarcinoma of prostate ClinVar PMID:26619011 NCBI chr  X:66,404,622...66,427,772
Ensembl chr  X:66,404,760...66,428,387
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor ISO human gene in mouse model RGD PMID:14522256 PMID:20195545 RGD:7207413, RGD:7207781 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Nfkbia NFKB inhibitor alpha severity ISO protein:increased serine phosphorylation RGD PMID:15712212 PMID:15073126 RGD:2298768, RGD:13506768 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Pam peptidylglycine alpha-amidating monooxygenase ISO mRNA:increased expression:prostate gland (human) RGD PMID:11221851 RGD:6483769 NCBI chr 9:97,998,581...98,271,966
Ensembl chr 9:98,122,916...98,271,965
JBrowse link
G Pdgfa platelet derived growth factor subunit A ISO protein:increased expression:prostate RGD PMID:7524068 RGD:2292156 NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha ISO protein:increased expression:prostate RGD PMID:7524068 RGD:2292156 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335
JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 treatment ISO RGD PMID:17562488 RGD:13506808 NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha ISO ClinVar Annotator: match by term: Adenocarcinoma of prostate ClinVar PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More... NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta treatment ISO RGD PMID:18755892 RGD:13217420 NCBI chr 8:99,594,600...99,699,772
Ensembl chr 8:99,594,644...99,699,663
JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha ISO ClinVar Annotator: match by term: Adenocarcinoma of prostate ClinVar PMID:25741868 PMID:26168268 PMID:26619011 NCBI chr 1:60,540,223...60,559,467
Ensembl chr 1:60,540,194...60,560,129
JBrowse link
G Prkcq protein kinase C, theta IEP mRNA:increased expression:prostate RGD PMID:8180127 RGD:1625625 NCBI chr17:67,246,394...67,379,049
Ensembl chr17:67,246,394...67,378,704
JBrowse link
G Pten phosphatase and tensin homolog ISO ClinVar Annotator: match by term: Adenocarcinoma of prostate ClinVar PMID:9467011 PMID:9915974 PMID:10866302 PMID:11504908 PMID:11875759 More... NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase treatment ISO RGD PMID:15754006 RGD:13506897 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit disease_progression ISO protein:increased expression:prostate gland RGD PMID:15712212 PMID:15073126 RGD:2298768, RGD:13506768 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Smad4 SMAD family member 4 ISO ClinVar Annotator: match by term: Adenocarcinoma of prostate ClinVar PMID:6604412 PMID:12116240 PMID:15031030 PMID:26619011 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
JBrowse link
G Spop speckle type BTB/POZ protein ISO ClinVar Annotator: match by term: Adenocarcinoma of prostate ClinVar PMID:23265383 PMID:26619011 NCBI chr10:80,358,121...80,438,983
Ensembl chr10:80,358,124...80,483,955
JBrowse link
G Stat1 signal transducer and activator of transcription 1 disease_progression ISO protein:increased activity:prostate RGD PMID:9748134 RGD:2290484 NCBI chr 9:49,419,561...49,459,969 JBrowse link
G Tert telomerase reverse transcriptase treatment ISO RGD PMID:19903903 RGD:11038656 NCBI chr 1:29,637,213...29,659,509
Ensembl chr 1:29,637,506...29,659,561
JBrowse link
G Tmprss2 transmembrane serine protease 2 disease_progression ISO protein:increased expression, altered localization:prostate gland RGD PMID:18338334 RGD:2324904 NCBI chr11:36,934,306...36,973,779
Ensembl chr11:36,934,306...36,973,715
JBrowse link
G Tp53 tumor protein p53 ISO ClinVar Annotator: match by term: Adenocarcinoma of prostate ClinVar PMID:1349175 PMID:1359493 PMID:1565143 PMID:1565144 PMID:1591732 More... NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Xpo1 exportin 1 ISO ClinVar Annotator: match by term: Adenocarcinoma of prostate ClinVar PMID:26619011 NCBI chr14:97,233,263...97,275,536
Ensembl chr14:97,233,270...97,275,498
JBrowse link
prostate carcinoma in situ term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amacr alpha-methylacyl-CoA racemase disease_progression ISO RGD PMID:18343427 RGD:2315630 NCBI chr 2:59,946,158...59,958,255
Ensembl chr 2:59,946,153...59,958,255
JBrowse link
G Ang angiogenin ISO RGD PMID:19276260 RGD:2325697 NCBI chr15:24,317,733...24,323,361 JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 ISO protein:increased expression, altered localization:prostate, cytoplasm RGD PMID:11309329 RGD:2315666 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785
JBrowse link
G Ar androgen receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20601956 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Areg amphiregulin ISO protein:increased expression:prostate gland RGD PMID:14716741 RGD:2292659 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
JBrowse link
G Atm ATM serine/threonine kinase ISO protein:increased serine phosphorylation:prostate gland RGD PMID:16997395 RGD:2293869 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Aurka aurora kinase A ISO protein:increased expression:prostate gland RGD PMID:15754349 PMID:16707419 RGD:2293883, RGD:2293877 NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390
JBrowse link
G Aurkb aurora kinase B ISO RGD PMID:16707419 RGD:2293877 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837
JBrowse link
G Btg2 BTG anti-proliferation factor 2 ISO protein:decreased expression:prostate gland RGD PMID:11470758 RGD:2289070 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
JBrowse link
G Carm1 coactivator-associated arginine methyltransferase 1 ISO protein:increased expression:prostate gland RGD PMID:15221992 RGD:2293206 NCBI chr 8:20,097,262...20,141,950
Ensembl chr 8:20,097,254...20,147,689
JBrowse link
G Ccnd1 cyclin D1 ISO mRNA, protein:decreased expression:prostate gland RGD PMID:14968434 RGD:2289283 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccne1 cyclin E1 ISO mRNA, protein:increased expression:prostate gland RGD PMID:14968434 RGD:2289283 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Cdh1 cadherin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22581815 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B ISO CTD Direct Evidence: therapeutic CTD PMID:20932324 PMID:18691549 RGD:2299085 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Creb3l4 cAMP responsive element binding protein 3-like 4 severity ISO RGD PMID:17270658 RGD:13504714 NCBI chr 2:175,690,340...175,696,084
Ensembl chr 2:175,690,335...175,695,932
JBrowse link
G Csf1r colony stimulating factor 1 receptor ISO protein:increased expression:prostate gland RGD PMID:12381783 RGD:2293712 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 ISO RGD PMID:19700748 RGD:7257711 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Dnmt1 DNA methyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22581815 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
JBrowse link
G Esr1 estrogen receptor 1 IDA
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:16220300 PMID:22025007 RGD:8553211 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 treatment IDA
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:16220300 PMID:22025007 RGD:8553211 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Fgf6 fibroblast growth factor 6 ISO protein:increased expression:prostate gland RGD PMID:2289066 RGD:2301089 NCBI chr 4:159,854,913...159,863,447
Ensembl chr 4:159,854,913...159,863,447
JBrowse link
G Fgf8 fibroblast growth factor 8 ISO RGD PMID:12208767 RGD:2301097 NCBI chr 1:244,584,477...244,590,359
Ensembl chr 1:244,584,652...244,590,359
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 ISO RGD PMID:18068632 RGD:2298702 NCBI chr16:66,492,445...66,546,731
Ensembl chr16:66,494,042...66,547,350
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 ISO RGD PMID:14695195 RGD:2301192 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 ISO protein:decreased expression:prostate gland RGD PMID:10893635 RGD:2301255 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
JBrowse link
G Fzd4 frizzled class receptor 4 ISO protein:increased expression:prostate gland RGD PMID:18068632 RGD:2298702 NCBI chr 1:143,280,065...143,288,799
Ensembl chr 1:143,280,065...143,285,724
JBrowse link
G Gstp1 glutathione S-transferase pi 1 IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:22581815 PMID:24312188 RGD:10401940 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Hdac1 histone deacetylase 1 ISO protein:increased expression:prostate gland RGD PMID:15042618 RGD:2306219 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111
JBrowse link
G Igf1 insulin-like growth factor 1 IEP protein:increased expression:prostate gland RGD PMID:19171036 RGD:2306713 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO RGD PMID:19117991 RGD:2314913 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Lef1 lymphoid enhancer binding factor 1 ISO RGD PMID:27067790 RGD:11531513 NCBI chr 2:219,666,549...219,779,815
Ensembl chr 2:219,666,592...219,779,794
JBrowse link
G Lrp1 LDL receptor related protein 1 IEP protein:increased expression:prostate gland RGD PMID:14623925 RGD:1625030 NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910
JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 disease_progression ISO RGD PMID:17577251 RGD:2293334 NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 disease_progression ISO RGD PMID:17577251 RGD:2293334 NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293
JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 disease_progression ISO RGD PMID:17577251 RGD:2293334 NCBI chr12:2,591,312...2,604,211
Ensembl chr12:2,591,219...2,604,222
JBrowse link
G Mt2A metallothionein 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:16574721 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor ISO RGD PMID:10861747 RGD:10059615 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Phb prohibitin ISO mRNA, protein:increased expression:prostate gland RGD PMID:18384941 RGD:2292382 NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042
JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23565217 NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174
JBrowse link
G Prss8 serine protease 8 disease_progression ISO mRNA, protein:increased expression:prostate gland RGD PMID:12518323 RGD:2292484 NCBI chr 1:182,536,229...182,540,745
Ensembl chr 1:182,536,229...182,540,815
JBrowse link
G Pten phosphatase and tensin homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:19081794 PMID:22581815 PMID:18268330 RGD:2292497 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO protein:altered localization RGD PMID:18468781 RGD:2300123 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit ISO protein:increased expression:prostate gland RGD PMID:16278667 PMID:15570007 RGD:2298767, RGD:2298769 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rxra retinoid X receptor alpha IEP protein:decreased expression:prostate RGD PMID:15318950 RGD:1643115 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
JBrowse link
G Slc30a4 solute carrier family 30 member 4 ISO protein:decreased expression:prostate gland RGD PMID:12955079 RGD:2299948 NCBI chr 3:109,753,270...109,775,306
Ensembl chr 3:109,753,273...109,775,306
JBrowse link
G Smad4 SMAD family member 4 ISO protein:increased expression:prostate gland RGD PMID:15017584 RGD:2300005 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
JBrowse link
G St14 ST14 transmembrane serine protease matriptase ISO protein:increased expression:prostate gland RGD PMID:18813126 RGD:2315088 NCBI chr 8:29,540,805...29,581,704
Ensembl chr 8:29,540,811...29,581,517
JBrowse link
G Stk11 serine/threonine kinase 11 ISO RGD PMID:18381428 RGD:2291943 NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315
JBrowse link
G Timp4 TIMP metallopeptidase inhibitor 4 ISO RGD PMID:16940965 RGD:2290433 NCBI chr 4:148,306,021...148,312,558
Ensembl chr 4:148,304,490...148,312,558
JBrowse link
G Top2b DNA topoisomerase II beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:20601956 NCBI chr15:9,051,661...9,111,220
Ensembl chr15:9,051,341...9,112,085
JBrowse link
G Tp63 tumor protein p63 ISO protein:decreased expression:prostate gland
CTD Direct Evidence: marker/mechanism
CTD PMID:22581815 PMID:17189982 PMID:17982114 RGD:2315434, RGD:2315433 NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398
JBrowse link
prostate small cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brca2 BRCA2, DNA repair associated ISO ClinVar Annotator: match by term: Metastatic Prostate Small Cell Carcinoma ClinVar PMID:11802209 PMID:15024741 PMID:15689453 PMID:20104584 PMID:21952622 More... NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17205
    disease of cellular proliferation 7034
      Neoplasms by Histologic Type 4765
        cell type cancer 3396
          carcinoma 2915
            prostate carcinoma 146
              adenosquamous prostate carcinoma 0
              castration-resistant prostate carcinoma 12
              prostate adenocarcinoma + 57
              prostate adenoid cystic carcinoma 0
              prostate carcinoma in situ 51
              prostate small cell carcinoma 1
              prostate squamous cell carcinoma 0
              prostate transitional cell carcinoma 0
Path 2
Term Annotations click to browse term
  disease 17205
    disease of anatomical entity 16551
      Urogenital Diseases 4356
        Male Urogenital Diseases 1860
          male reproductive system disease 1860
            Male Genital Neoplasms 1307
              male reproductive organ cancer 806
                prostate cancer 803
                  prostate carcinoma 146
                    adenosquamous prostate carcinoma 0
                    castration-resistant prostate carcinoma 12
                    prostate adenocarcinoma + 57
                    prostate adenoid cystic carcinoma 0
                    prostate carcinoma in situ 51
                    prostate small cell carcinoma 1
                    prostate squamous cell carcinoma 0
                    prostate transitional cell carcinoma 0
paths to the root