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ONTOLOGY REPORT - ANNOTATIONS


Term:osteonecrosis
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Accession:DOID:10159 term browser browse the term
Definition:Death of a bone or part of a bone, either atraumatic or posttraumatic.
Synonyms:exact_synonym: Bone Aseptic Necrosis;   Bone Avascular Necrosis;   Bone Necroses;   Bone Necrosis;   Kienbock Disease;   Kienbock's Disease;   Kienboeck Disease;   Kienboeck's Disease;   Kienboecks disease;   aseptic necrosis;   aseptic necrosis of bone;   avascular necrosis of bone;   osteonecroses
 primary_id: MESH:D010020
 alt_id: RDO:0001643
 xref: ICD10CM:M87;   ICD10CM:M87.9;   ICD9CM:732.3;   ICD9CM:733.41;   ICD9CM:733.42;   ICD9CM:733.43;   ICD9CM:733.44;   NCI:C34404;   NCI:C34841;   NCI:C34880;   NCI:C35226;   NCI:C35517;   OMIM:PS608805
For additional species annotation, visit the Alliance of Genome Resources.


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osteonecrosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anxa2 annexin A2 JBrowse link 8 75,687,134 75,723,589 RGD:1578382
G Mmp2 matrix metallopeptidase 2 JBrowse link 19 15,542,771 15,570,589 RGD:11554173
G Mthfr methylenetetrahydrofolate reductase JBrowse link 5 164,844,642 164,864,360 RGD:10449417
G Plg plasminogen JBrowse link 1 48,521,828 48,563,895 RGD:30309948
RGD:30309951
G Proc protein C, inactivator of coagulation factors Va and VIIIa JBrowse link 18 24,918,402 24,928,822 RGD:30309948
RGD:30309951
G Serpinc1 serpin family C member 1 JBrowse link 13 78,806,107 78,820,375 RGD:30309951
RGD:30309948
G Vwf von Willebrand factor JBrowse link 4 158,085,059 158,219,525 RGD:30309948
ARTHROGRYPOSIS, PERTHES DISEASE, AND UPWARD GAZE PALSY term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nek9 NIMA-related kinase 9 JBrowse link 6 109,121,524 109,162,433 RGD:8554872
RGD:7240710
Bisphosphonate-Associated Osteonecrosis of the Jaw term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:11041182
Femur Head Necrosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G A2m alpha-2-macroglobulin JBrowse link 4 154,309,426 154,359,138 RGD:10046018
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:9479160
G Col2a1 collagen type II alpha 1 chain JBrowse link 7 139,454,945 139,484,403 RGD:7240710
RGD:8554872
RGD:10046018
G F2 coagulation factor II JBrowse link 3 80,529,468 80,542,993 RGD:6902907
G F5 coagulation factor V JBrowse link 13 82,479,997 82,535,540 RGD:6902907
G Gstm1 glutathione S-transferase mu 1 JBrowse link 2 210,803,869 210,809,461 RGD:10450838
G Gstt1 glutathione S-transferase theta 1 JBrowse link 20 13,799,102 13,816,527 RGD:10450838
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:11087286
G Lrp5 LDL receptor related protein 5 JBrowse link 1 218,816,833 218,920,147 RGD:12793062
G Mia MIA SH3 domain containing JBrowse link 1 83,991,577 83,993,270 RGD:10046018
G Plat plasminogen activator, tissue type JBrowse link 16 74,098,263 74,122,897 RGD:11541046
G Pomc proopiomelanocortin JBrowse link 6 28,382,937 28,388,771 RGD:11554173
G Tfpi tissue factor pathway inhibitor JBrowse link 3 71,852,738 71,902,127 RGD:11060260
RGD:11062059
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 JBrowse link 12 47,698,915 47,737,902 RGD:7240710
RGD:8554872
Legg-Calve-Perthes disease term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Col2a1 collagen type II alpha 1 chain JBrowse link 7 139,454,945 139,484,403 RGD:7240710
RGD:8554872
G Gnptab N-acetylglucosamine-1-phosphate transferase subunits alpha and beta JBrowse link 7 28,956,363 29,023,232 RGD:8554872

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16022
    Pathological Conditions, Signs and Symptoms 8489
      Pathologic Processes 5981
        Necrosis 89
          osteonecrosis 24
            ARTHROGRYPOSIS, PERTHES DISEASE, AND UPWARD GAZE PALSY 1
            Bilateral Kienbock's Disease 0
            Bisphosphonate-Associated Osteonecrosis of the Jaw 1
            Dieterich's Disease 0
            Femur Head Necrosis + 16
Path 2
Term Annotations click to browse term
  disease 16022
    disease of anatomical entity 15275
      musculoskeletal system disease 5539
        connective tissue disease 4007
          bone disease 3471
            ischemic bone disease 27
              osteonecrosis 24
                ARTHROGRYPOSIS, PERTHES DISEASE, AND UPWARD GAZE PALSY 1
                Bilateral Kienbock's Disease 0
                Bisphosphonate-Associated Osteonecrosis of the Jaw 1
                Dieterich's Disease 0
                Femur Head Necrosis + 16
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.