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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:endometrial disease
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Accession:DOID:1005 term browser browse the term
Definition:A uterine disease that is located_in the endometrium. (DO)
Synonyms:exact_synonym: endometrial diseases
 xref: NCI:C3504
For additional species annotation, visit the Alliance of Genome Resources.



show annotations for term's descendants           Sort by:
 
endometrial adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANGPT1 angiopoietin 1 IEP protein:increased expression:endometrium epithelium RGD PMID:17295646 RGD:2293852 NCBI chr 8:107,249,482...107,497,918
Ensembl chr 8:107,249,482...107,498,055
JBrowse link
G ANGPT2 angiopoietin 2 IEP protein:increased expression:endometrium epithelium RGD PMID:17295646 RGD:2293852 NCBI chr 8:6,499,632...6,563,245
Ensembl chr 8:6,499,632...6,563,409
JBrowse link
G ARID1A AT-rich interaction domain 1A treatment IMP
IEA
human cell in mouse model MouseDO
RGD
PMID:21900401 RGD:126725086 NCBI chr 1:26,696,015...26,782,104
Ensembl chr 1:26,693,236...26,782,104
JBrowse link
G AXIN2 axin 2 IGI
IEA
MouseDO
RGD
PMID:11940574 RGD:13432156 NCBI chr17:65,528,563...65,561,648
Ensembl chr17:65,528,563...65,561,648
JBrowse link
G BET1L Bet1 golgi vesicular membrane trafficking protein like disease_progression IEP RGD PMID:28654152 RGD:14394612 NCBI chr11:202,924...207,399
Ensembl chr11:167,784...207,399
JBrowse link
G CD55 CD55 molecule (Cromer blood group) IEP RGD PMID:11506079 RGD:2326173 NCBI chr 1:207,321,678...207,360,966
Ensembl chr 1:207,321,519...207,386,804
JBrowse link
G EBAG9 estrogen receptor binding site associated antigen 9 IEP protein:increased expression:endometrium RGD PMID:16112719 RGD:2289850 NCBI chr 8:109,539,702...109,565,996
Ensembl chr 8:109,539,711...109,570,072
JBrowse link
G FOXO3 forkhead box O3 severity IEP associated with Obesity;protein:decreased expression:endometrium (human) RGD PMID:26045339 RGD:11530998 NCBI chr 6:108,559,825...108,684,774
Ensembl chr 6:108,559,835...108,684,774
JBrowse link
G GPX3 glutathione peroxidase 3 ISO mRNA:decreased expression:endometrium (rat) RGD PMID:19426485 RGD:2312621 NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988
JBrowse link
G IRF1 interferon regulatory factor 1 ISO DNA:deletions (rat) RGD PMID:19075038 RGD:5128782 NCBI chr 5:132,481,609...132,490,773
Ensembl chr 5:132,440,440...132,508,719
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit no_association IEP protein, mRNA::endometrial epithelium and stroma:no correlation between expression and type of tissue or cancer stage or grade RGD PMID:10684716 RGD:2290482 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
JBrowse link
G KRAS KRAS proto-oncogene, GTPase ISO DNA:point mutation:CDS:p.G12D, p.G12S, p.Q61H (rat) RGD PMID:10775052 RGD:1600499 NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 treatment IDA
IEA
IEP
human tumor in a mouse model
protein:decreased phosphorylation:endometrium (human)
MouseDO
RGD
PMID:23402905 PMID:14760076 RGD:13703125, RGD:13703137 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 treatment IDA
IEA
IEP
human tumor in a mouse model
protein:decreased phosphorylation:endometrium (human)
MouseDO
RGD
PMID:23402905 PMID:14760076 RGD:13703125, RGD:13703137 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 IAGP
IEA
DNA:mutations:multiple (human) MouseDO
RGD
PMID:21478295 RGD:13441595 NCBI chr 5:68,215,756...68,301,821
Ensembl chr 5:68,215,740...68,301,821
JBrowse link
G PTEN phosphatase and tensin homolog ameliorates ISO RGD PMID:32843721 RGD:127285600 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930
JBrowse link
G PTGES prostaglandin E synthase IEP protein:increased expression:endometrium RGD PMID:11592775 RGD:2300089 NCBI chr 9:129,738,349...129,753,042
Ensembl chr 9:129,738,331...129,753,042
JBrowse link
G RRM2 ribonucleotide reductase regulatory subunit M2 ISO DNA:amplification (rat) RGD PMID:15942940 RGD:2324953 NCBI chr 2:10,122,568...10,211,010
Ensembl chr 2:10,120,698...10,211,725
JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 IEP mRNA:decreased expression:endometrium RGD PMID:15745937 RGD:1579943 NCBI chr 1:91,680,343...91,906,002
Ensembl chr 1:91,680,343...91,906,335
JBrowse link
G TP53 tumor protein p53 disease_progression IEP
IEA
IAGP
protein:increased expression:endometrium
DNA:missense mutations
MouseDO
RGD
PMID:1540970 PMID:1540970 RGD:2290541, RGD:2290541 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G TSG101 tumor susceptibility 101 IDA
IEA
mRNA:alternative forms MouseDO
RGD
PMID:10027311 RGD:2291854 NCBI chr11:18,480,311...18,526,942
Ensembl chr11:18,468,336...18,526,951
JBrowse link
endometrial cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRB3 adrenoceptor beta 3 susceptibility IAGP
IEA
associated with Obesity;DNA:polymorphism: :p.W64R (human)
OMIM:608089
MouseDO
RGD
PMID:15743038 RGD:2313164 NCBI chr 8:37,962,990...37,966,599
Ensembl chr 8:37,962,990...37,966,599
JBrowse link
G AFP alpha fetoprotein severity IEP protein:increased expression:serum RGD PMID:17659325 RGD:2292039 NCBI chr 4:73,436,221...73,456,174
Ensembl chr 4:73,431,138...73,456,174
JBrowse link
G AKT2 AKT serine/threonine kinase 2 severity IAGP
IEA
DNA:snp:intron:c.287+993G>A (rs892119) (human)
OMIM:608089
MouseDO
RGD
PMID:22146979 RGD:13432140 NCBI chr19:40,230,317...40,285,345
Ensembl chr19:40,230,317...40,285,536
JBrowse link
G ANG angiogenin IEP protein:increased expression:serum RGD PMID:9119882 RGD:2317659 NCBI chr14:20,684,177...20,694,186
Ensembl chr14:20,684,177...20,698,971
JBrowse link
G APC APC regulator of WNT signaling pathway severity
treatment
ISO
IEA
IEP
IAGP
IDA
with Pten knockout
OMIM:608089
protein:increased expression:endometrium (human)
DNA:mutations, haplotype:cds:multiple (human)
human cells in a mouse model
MouseDO
RGD
PMID:23288720 PMID:15951972 PMID:29876005 PMID:22907428 RGD:13524585, RGD:13673917, RGD:13673916, RGD:13524624 NCBI chr 5:112,707,498...112,846,239
Ensembl chr 5:112,707,498...112,846,239
JBrowse link
G APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 IAGP
IEA
DNA:nonsense mutation, missense mutations: :p.W188X, p.P112L, p.R237C (human)
OMIM:608089
MouseDO
RGD
PMID:11465542 RGD:2315878 NCBI chr14:20,455,226...20,457,767
Ensembl chr14:20,455,191...20,457,772
JBrowse link
G AR androgen receptor IAGP
IEA
OMIM:608089 MouseDO
RGD
PMID:15721279 RGD:1578689 NCBI chr  X:67,544,021...67,730,619
Ensembl chr  X:67,544,021...67,730,619
JBrowse link
G ARID1A AT-rich interaction domain 1A onset HEP protein:decreased expression:endometrium (human) RGD PMID:23887303 RGD:126779522 NCBI chr 1:26,696,015...26,782,104
Ensembl chr 1:26,693,236...26,782,104
JBrowse link
G ATM ATM serine/threonine kinase susceptibility IAGP
IEA
OMIM:608089 MouseDO
RGD
PMID:17164260 RGD:2293868 NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,223,044...108,369,102
JBrowse link
G BAD BCL2 associated agonist of cell death disease progression IAGP
IEA
protein:altered expression:endometrium (human)
OMIM:608089
MouseDO
RGD
PMID:24645842 RGD:13432164 NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704
JBrowse link
G BAG1 BAG cochaperone 1 IEP protein:increased expression:endometrium RGD PMID:15297164 RGD:2293886 NCBI chr 9:33,252,471...33,264,708
Ensembl chr 9:33,247,820...33,264,720
JBrowse link
G BCL2L1 BCL2 like 1 IEP protein:increased expression:endometrium RGD PMID:17311011 RGD:1643476 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989
JBrowse link
G BRCA2 BRCA2 DNA repair associated IAGP
IEA
DNA:deletion, frameshift mutation
OMIM:608089
MouseDO
RGD
PMID:10451700 RGD:2296027 NCBI chr13:32,315,508...32,400,268
Ensembl chr13:32,315,086...32,400,268
JBrowse link
G BST2 bone marrow stromal cell antigen 2 treatment IMP
IEA
IEP
OMIM:608089
protein:increased expression:endometrium:
MouseDO
RGD
PMID:26498112 PMID:22729361 PMID:22729361 RGD:14398492, RGD:14398498, RGD:14398498 NCBI chr19:17,402,939...17,405,630
Ensembl chr19:17,402,939...17,405,630
JBrowse link
G CD59 CD59 molecule (CD59 blood group) IEP protein:increased expression:endometrium RGD PMID:10637067 RGD:2293548 NCBI chr11:33,703,010...33,736,479
Ensembl chr11:33,703,010...33,736,479
JBrowse link
G CD9 CD9 molecule IEP RGD PMID:11505398 RGD:2326208 NCBI chr12:6,199,946...6,238,266
Ensembl chr12:6,199,715...6,238,271
JBrowse link
G CDC25B cell division cycle 25B IEP RGD PMID:14559803 RGD:4105451 NCBI chr20:3,786,951...3,806,115
Ensembl chr20:3,786,772...3,806,121
JBrowse link
G CDC25C cell division cycle 25C IAGP
IEA
DNA:mutation (human)
OMIM:608089
MouseDO
RGD
PMID:12124347 RGD:4105455 NCBI chr 5:138,285,265...138,338,355
Ensembl chr 5:138,285,269...138,338,355
JBrowse link
G CDH1 cadherin 1 IAGP OMIM NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A ISO DNA:deletions:exon (rat) RGD PMID:18558284 RGD:2316081 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301
JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B ISO DNA:deletion (rat) RGD PMID:18558284 RGD:2316081 NCBI chr 9:22,002,903...22,009,313
Ensembl chr 9:22,002,903...22,009,305
JBrowse link
G CHI3L1 chitinase 3 like 1 severity IEP protein:increased secretion:serum (human) RGD PMID:17023034 RGD:4892642 NCBI chr 1:203,178,931...203,186,704
Ensembl chr 1:203,178,931...203,186,704
JBrowse link
G COMT catechol-O-methyltransferase susceptibility
no_association
IAGP
IEA
IDA
DNA:polymorphism: :p.V158M
OMIM:608089
DNA:hypermethylation:promoter
MouseDO
RGD
PMID:17442187 PMID:12810635 PMID:15285606 RGD:2289714, RGD:2289723, RGD:2289721 NCBI chr22:19,941,772...19,969,975
Ensembl chr22:19,941,371...19,969,975
JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 IAGP
IEA
DNA:SNP::increase in frequency of mutant heterozygote C/T (p=0.0004)
OMIM:608089
MouseDO
RGD
PMID:18497059 RGD:2301045 NCBI chr15:51,208,057...51,338,596
Ensembl chr15:51,208,057...51,338,601
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 IAGP
IEA
DNA:SNP:CDS:rs4646903 T/T genotype, rs4646903-rs1048943 T-A haplotype, rs4646903 (TT) combined with SULT1A1 SNP rs9282861 (GA + AA) or rs4646903 (TT) combined with SULT1E1 SNP rs3736599 (GA+AA)
OMIM:608089
MouseDO
RGD
PMID:18318428 RGD:2301040 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 IAGP
IEA
DNA:SNP::differences in allele and genotype distribution for CYP1A2*1F polymorphism (p=0.00000002)
OMIM:608089
MouseDO
RGD
PMID:18497059 RGD:2301045 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607
JBrowse link
G EFEMP2 EGF containing fibulin extracellular matrix protein 2 exacerbates
ameliorates
IEP
IEA
IMP
protein:decreased expression:endometrium (human)
OMIM:608089
human EFEMP2 knockdown cell line in a mouse model
MouseDO
RGD
PMID:28177909 PMID:28177909 RGD:42722012, RGD:42722012 NCBI chr11:65,866,441...65,872,800
Ensembl chr11:65,866,441...65,873,592
JBrowse link
G EGF epidermal growth factor severity IAGP
IEA
DNA:snps:5'utr:multiple (human)
OMIM:608089
MouseDO
RGD
PMID:19319135 RGD:13673915 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766
JBrowse link
G ERRFI1 ERBB receptor feedback inhibitor 1 ISS OMIM:608089 MouseDO NCBI chr 1:8,011,727...8,026,309
Ensembl chr 1:8,004,404...8,026,309
JBrowse link
G FGF1 fibroblast growth factor 1 disease_progression IEP mRNA:increased expression:myometrium RGD PMID:8685603 RGD:2298516 NCBI chr 5:142,592,178...142,698,070
Ensembl chr 5:142,592,178...142,698,070
JBrowse link
G FGF2 fibroblast growth factor 2 disease_progression IEP mRNA, protein:increased expression:myometrium RGD PMID:8685603 RGD:2298516 NCBI chr 4:122,826,682...122,898,236
Ensembl chr 4:122,826,708...122,898,236
JBrowse link
G GHRH growth hormone releasing hormone IEP
IEA
IMP
mRNA:increased expression:tumor:expression in 17/22 specimens
OMIM:608089
MouseDO
RGD
PMID:10022420 PMID:15784701 RGD:2289974, RGD:2301423 NCBI chr20:37,251,086...37,261,814
Ensembl chr20:37,251,086...37,261,819
JBrowse link
G HOXB13 homeobox B13 IEP RGD PMID:15756448 RGD:2314730 NCBI chr17:48,724,763...48,728,750
Ensembl chr17:48,724,763...48,728,750
JBrowse link
G HTRA2 HtrA serine peptidase 2 IEP protein:decreased expression:endometrium (human) RGD PMID:19424634 RGD:5688747 NCBI chr 2:74,529,405...74,533,556
Ensembl chr 2:74,529,596...74,533,350
JBrowse link
G IL10 interleukin 10 IEP protein:increased expression:serum RGD PMID:9119882 RGD:2317659 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G JAK1 Janus kinase 1 severity IAGP
IEA
DNA:frameshift mutations
OMIM:608089
MouseDO
RGD
PMID:29121062 RGD:150524355 NCBI chr 1:64,833,229...65,067,746
Ensembl chr 1:64,833,223...65,067,754
JBrowse link
G JUP junction plakoglobin IEP protein:decreased expression:endometrium RGD PMID:12635138 RGD:2301747 NCBI chr17:41,754,609...41,786,711
Ensembl chr17:41,754,604...41,786,931
JBrowse link
G LTA lymphotoxin alpha susceptibility IAGP
IEA
DNA:polymorphism: :252A>G, 804C>A (human)
OMIM:608089
MouseDO
RGD
PMID:17045328 RGD:2313259 NCBI chr 6:31,560,610...31,574,324
Ensembl chr 6:31,572,054...31,574,324
JBrowse link
G MCPH1 microcephalin 1 IAGP
IEA
DNA:deletions:exons:multiple (human)
OMIM:608089
MouseDO
RGD
PMID:20638839 RGD:9589018 NCBI chr 8:6,406,627...6,648,508
Ensembl chr 8:6,406,592...6,648,508
JBrowse link
G MIR21 microRNA 21 IEP miRNA:increased expression:endometrium RGD PMID:33408517 RGD:126775148 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337
JBrowse link
G MLH3 mutL homolog 3 IAGP ClinVar Annotator: match by term: endometrial cancer OMIM
ClinVar
PMID:12702580 NCBI chr14:75,013,775...75,051,467
Ensembl chr14:75,013,769...75,051,532
JBrowse link
G MMP7 matrix metallopeptidase 7 disease_progression IEP protein:increased expression:endometrium RGD PMID:17352221 RGD:2298522 NCBI chr11:102,520,508...102,530,747
Ensembl chr11:102,520,508...102,530,750
JBrowse link
G MRE11 MRE11 homolog, double strand break repair nuclease IAGP
IEA
DNA:deletions:intron:IVS4_delT (human)
OMIM:608089
MouseDO
RGD
PMID:15048091 RGD:2317737 NCBI chr11:94,415,570...94,512,412
Ensembl chr11:94,415,570...94,493,885
JBrowse link
G MSH3 mutS homolog 3 IAGP OMIM NCBI chr 5:80,654,652...80,876,815
Ensembl chr 5:80,654,652...80,876,815
JBrowse link
G MSH6 mutS homolog 6 IAGP OMIM NCBI chr 2:47,783,145...47,806,953
Ensembl chr 2:47,695,530...47,810,063
JBrowse link
G MUTYH mutY DNA glycosylase IAGP ClinVar Annotator: match by term: Endometrial cancer, somatic ClinVar PMID:11818965 PMID:12606733 PMID:12917422 PMID:15931596 PMID:15987719 More... NCBI chr 1:45,329,242...45,340,440
Ensembl chr 1:45,329,163...45,340,893
JBrowse link
G NOTCH1 notch receptor 1 IEP mRNA:increased expression:endometrium RGD PMID:11078798 RGD:2299153 NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048
JBrowse link
G NOTCH4 notch receptor 4 IEP mRNA:decreased expression:endometrium RGD PMID:11078798 RGD:2299153 NCBI chr 6:32,194,843...32,224,067
Ensembl chr 6:32,194,843...32,224,067
JBrowse link
G PGM1 phosphoglucomutase 1 IAGP
IEA
OMIM:608089 MouseDO
RGD
PMID:508567 RGD:2299870 NCBI chr 1:63,593,411...63,660,245
Ensembl chr 1:63,593,411...63,660,245
JBrowse link
G PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta onset IEP mRNA:increased expression:endometrium (human) RGD PMID:28002804 RGD:13674181 NCBI chr 3:138,652,698...138,834,928
Ensembl chr 3:138,652,698...138,834,928
JBrowse link
G PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta IGI
IEA
OMIM:608089 MouseDO
RGD
PMID:21478295 RGD:13441595 NCBI chr 1:9,627,258...9,729,114
Ensembl chr 1:9,629,889...9,729,114
JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 IAGP
IEA
DNA:mutations:multiple (human)
OMIM:608089
MouseDO
RGD
PMID:21984976 RGD:13674179 NCBI chr 5:68,215,756...68,301,821
Ensembl chr 5:68,215,740...68,301,821
JBrowse link
G POLE DNA polymerase epsilon, catalytic subunit disease_progression
ameliorates
onset
HEP
IEA
IAGP
protein:increased expression:endometrium (human)
OMIM:608089
DNA:missense mutations:CDS:p.P286R, p.V411L (human)
DNA:missense mutations:multiple (human)
DNA:polymorphisms:multiple (human)
MouseDO
RGD
PMID:31866764 PMID:29659608 PMID:29559562 PMID:25224212 RGD:151347644, RGD:151347857, RGD:151347650, RGD:151347645 NCBI chr12:132,623,762...132,687,342
Ensembl chr12:132,623,753...132,687,376
JBrowse link
G PTEN phosphatase and tensin homolog ISS OMIM:608089 MouseDO NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930
JBrowse link
G RNF43 ring finger protein 43 IAGP
IEA
DNA:mutations:multiple: (human)
OMIM:608089
MouseDO
RGD
PMID:25344691 RGD:151361224 NCBI chr17:58,352,500...58,417,534
Ensembl chr17:58,353,676...58,417,595
JBrowse link
G RUNX1 RUNX family transcription factor 1 IEP mRNA:decreased expression:endometrium RGD PMID:33408517 RGD:126775148 NCBI chr21:34,787,801...35,049,302
Ensembl chr21:34,787,801...36,004,667
JBrowse link
G SHBG sex hormone binding globulin IAGP
IEA
DNA:polymorphism:exon:p.D327N (human)
OMIM:608089
MouseDO
RGD
PMID:17315164 RGD:1625245 NCBI chr17:7,614,064...7,633,372
Ensembl chr17:7,613,946...7,633,382
JBrowse link
G SMAD2 SMAD family member 2 IEP protein:increased expression:endometrium RGD PMID:12883738 RGD:2299970 NCBI chr18:47,808,957...47,930,872
Ensembl chr18:47,808,957...47,931,146
JBrowse link
G SMAD3 SMAD family member 3 IEP protein:increased expression:endometrium RGD PMID:12883738 RGD:2299970 NCBI chr15:67,065,602...67,195,169
Ensembl chr15:67,063,763...67,195,173
JBrowse link
G SMAD7 SMAD family member 7 disease_progression IEP mRNA:increased expression:endometrium RGD PMID:15661223 RGD:2299963 NCBI chr18:48,919,853...48,950,965
Ensembl chr18:48,919,853...48,950,965
JBrowse link
G SOCS2 suppressor of cytokine signaling 2 IDA
IEA
DNA:hypermethylated
OMIM:608089
MouseDO
RGD
PMID:15159323 RGD:2298926 NCBI chr12:93,569,969...93,626,236
Ensembl chr12:93,569,814...93,583,487
JBrowse link
G SPAG9 sperm associated antigen 9 IEP protein:increased expression:serum: RGD PMID:24460345 RGD:30296659 NCBI chr17:50,962,174...51,120,868
Ensembl chr17:50,962,174...51,120,868
JBrowse link
G STK11 serine/threonine kinase 11 ISO
ISS
IEP
OMIM:608089 MouseDO
RGD
PMID:18245476 PMID:18245476 RGD:2291944, RGD:2291944 NCBI chr19:1,205,778...1,228,431
Ensembl chr19:1,177,558...1,228,431
JBrowse link
G SULT1A1 sulfotransferase family 1A member 1 IAGP
IEA
OMIM:608089 MouseDO
RGD
PMID:16985250 RGD:1581436 NCBI chr16:28,605,258...28,623,375
Ensembl chr16:28,605,196...28,614,279
JBrowse link
G SULT1E1 sulfotransferase family 1E member 1 IAGP
IEA
DNA:SNP:haplotype:rs3736599 (GA+AA) combined with SULT1A1 SNP rs9282861 (GA + AA) or with CYP1A1 SNP rs4646903 (TT)
OMIM:608089
MouseDO
RGD
PMID:18318428 RGD:2301040 NCBI chr 4:69,821,122...69,860,145
Ensembl chr 4:69,841,212...69,860,145
JBrowse link
G TFF1 trefoil factor 1 IEP mRNA, protein:increased expression:endometrium RGD PMID:10835496 RGD:2298569 NCBI chr21:42,362,282...42,366,535
Ensembl chr21:42,362,282...42,366,535
JBrowse link
G TIMP4 TIMP metallopeptidase inhibitor 4 IEP mRNA:decreased expression:endometrium RGD PMID:15273280 RGD:2290435 NCBI chr 3:12,153,068...12,158,912
Ensembl chr 3:12,153,068...12,158,912
JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A IEP protein:increased expression:serum (human) RGD PMID:8920779 RGD:5131439 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114
JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B IEP protein:increased expression:serum (human) RGD PMID:8920779 RGD:5131439 NCBI chr 1:12,166,991...12,209,220
Ensembl chr 1:12,166,991...12,209,228
JBrowse link
G TP53 tumor protein p53 ISS OMIM:608089 MouseDO NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G TYMP thymidine phosphorylase IEP RGD PMID:18348659 RGD:2293715 NCBI chr22:50,525,752...50,530,085
Ensembl chr22:50,525,752...50,530,032
JBrowse link
G UGT1A1 UDP glucuronosyltransferase family 1 member A1 IAGP
IEA
DNA:SNP: :rs2070959 (human)
OMIM:608089
MouseDO
RGD
PMID:18349273 RGD:2315450 NCBI chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300
JBrowse link
G WT1 WT1 transcription factor disease_progression IEP RGD PMID:19443388 RGD:2315542 NCBI chr11:32,387,775...32,435,539
Ensembl chr11:32,387,775...32,435,564
JBrowse link
endometrial carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA3 ATP binding cassette subfamily A member 3 IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chr16:2,275,881...2,340,728
Ensembl chr16:2,275,881...2,340,746
JBrowse link
G APC APC regulator of WNT signaling pathway onset IAGP
IEA
ISO
DNA:hypermethylation:promoter: (human)
ClinVar Annotator: match by term: Endometrial carcinoma
MouseDO
ClinVar
RGD
PMID:25741868 PMID:28492532 PMID:19900189 PMID:21363919 RGD:13524625, RGD:13525011 NCBI chr 5:112,707,498...112,846,239
Ensembl chr 5:112,707,498...112,846,239
JBrowse link
G AREL1 apoptosis resistant E3 ubiquitin protein ligase 1 IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:12702580 PMID:17656264 PMID:22290698 PMID:28492532 NCBI chr14:74,661,256...74,713,080
Ensembl chr14:74,653,437...74,713,117
JBrowse link
G ATM ATM serine/threonine kinase IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:133608 PMID:12810666 PMID:19781682 PMID:21787400 PMID:23555315 More... NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,223,044...108,369,102
JBrowse link
G AURKA aurora kinase A IEP mRNA, protein:increased expression:endometrium RGD PMID:16311121 RGD:2293878 NCBI chr20:56,369,390...56,392,215
Ensembl chr20:56,369,389...56,392,337
JBrowse link
G AURKB aurora kinase B disease_progression IEP mRNA, protein:increased expression:endometrium RGD PMID:16311121 RGD:2293878 NCBI chr17:8,204,731...8,210,575
Ensembl chr17:8,204,733...8,210,600
JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase IAGP
IEA
DNA:missense mutations, nonsense mutation:cds:multiple (human)
ClinVar Annotator: match by term: Endometrial carcinoma
MouseDO
ClinVar
RGD
PMID:28492532 PMID:16144912 RGD:13432166 NCBI chr 7:140,713,328...140,924,929
Ensembl chr 7:140,719,327...140,924,929
JBrowse link
G BRCA1 BRCA1 DNA repair associated IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:7581445 PMID:10667592 PMID:10667595 PMID:12566964 PMID:12955716 More... NCBI chr17:43,044,295...43,125,364
Ensembl chr17:43,044,295...43,170,245
JBrowse link
G BRCA2 BRCA2 DNA repair associated IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:20104584 PMID:22476429 PMID:22703879 PMID:24448499 PMID:24916970 More... NCBI chr13:32,315,508...32,400,268
Ensembl chr13:32,315,086...32,400,268
JBrowse link
G BRICD5 BRICHOS domain containing 5 IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chr16:2,209,253...2,210,863
Ensembl chr16:2,209,253...2,210,905
JBrowse link
G BSG basigin (Ok blood group) disease_progression IEP protein:increased expression:endometrium RGD PMID:17342307 RGD:2296029 NCBI chr19:571,283...583,493
Ensembl chr19:571,277...583,494
JBrowse link
G C11orf65 chromosome 11 open reading frame 65 IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:12810666 PMID:19781682 PMID:21787400 PMID:23555315 PMID:25741868 More... NCBI chr11:108,308,519...108,469,881
Ensembl chr11:108,308,519...108,467,531
JBrowse link
G CASKIN1 CASK interacting protein 1 IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chr16:2,177,180...2,196,605
Ensembl chr16:2,177,180...2,196,605
JBrowse link
G CCNB1 cyclin B1 IEP RGD PMID:17483252 RGD:2289230 NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245
JBrowse link
G CD82 CD82 molecule disease_progression IEP RGD PMID:12684410 RGD:2289403 NCBI chr11:44,564,409...44,620,358
Ensembl chr11:44,564,427...44,620,358
JBrowse link
G CDH1 cadherin 1 IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:8075649 PMID:11598162 PMID:11747475 PMID:12588804 PMID:14500541 More... NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537
JBrowse link
G CDH13 cadherin 13 disease_progression IDA
IEA
DNA:hypomethylation MouseDO
RGD
PMID:18519763 RGD:2298985 NCBI chr16:82,626,969...83,800,640
Ensembl chr16:82,626,965...83,800,640
JBrowse link
G CHEK2 checkpoint kinase 2 IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:25186627 PMID:25741868 PMID:26094658 PMID:26467025 PMID:28492532 More... NCBI chr22:28,687,743...28,741,834
Ensembl chr22:28,687,743...28,742,422
JBrowse link
G DHFR dihydrofolate reductase IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:25741868 NCBI chr 5:80,626,226...80,654,983
Ensembl chr 5:80,626,226...80,654,983
JBrowse link
G DNASE1L2 deoxyribonuclease 1 like 2 IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chr16:2,236,444...2,238,711
Ensembl chr16:2,235,816...2,238,711
JBrowse link
G E4F1 E4F transcription factor 1 IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chr16:2,223,591...2,235,742
Ensembl chr16:2,223,580...2,235,742
JBrowse link
G ECI1 enoyl-CoA delta isomerase 1 IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chr16:2,239,402...2,251,587
Ensembl chr16:2,239,402...2,252,300
JBrowse link
G EGFR epidermal growth factor receptor IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:28492532 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
JBrowse link
G ERAP1 endoplasmic reticulum aminopeptidase 1 disease_progression IEP RGD PMID:15741767 RGD:2315693 NCBI chr 5:96,760,813...96,935,854
Ensembl chr 5:96,760,810...96,808,100
JBrowse link
G FGF7 fibroblast growth factor 7 IEP mRNA:decreased expression:endometrium RGD PMID:9070494 RGD:2301091 NCBI chr15:49,423,242...49,488,775
Ensembl chr15:49,423,237...49,488,775
JBrowse link
G FGFR2 fibroblast growth factor receptor 2 IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:7719344 PMID:8651276 PMID:8696350 PMID:9462761 PMID:9719378 More... NCBI chr10:121,478,330...121,598,458
Ensembl chr10:121,478,332...121,598,458
JBrowse link
G FGFR3 fibroblast growth factor receptor 3 IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chr 4:1,793,293...1,808,867
Ensembl chr 4:1,793,293...1,808,872
JBrowse link
G GRB2 growth factor receptor bound protein 2 severity IEP Shc-Grb2 complex;protein:increased expression:serum (human) RGD PMID:22459351 RGD:13441552 NCBI chr17:75,318,076...75,405,678
Ensembl chr17:75,318,076...75,405,709
JBrowse link
G GSK3B glycogen synthase kinase 3 beta severity IEP protein:increased expression:endometrium (human) RGD PMID:27050373 RGD:13524565 NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994
JBrowse link
G H19 H19 imprinted maternally expressed transcript severity IEP mRNA:increased expression:endometrium RGD PMID:15228427 RGD:2306178 NCBI chr11:1,995,176...2,001,466
Ensembl chr11:1,995,166...2,001,470
JBrowse link
G HDAC3 histone deacetylase 3 disease_progression IEP RGD PMID:18714364 RGD:2306205 NCBI chr 5:141,620,881...141,636,849
Ensembl chr 5:141,620,876...141,636,849
JBrowse link
G HRAS HRas proto-oncogene, GTPase disease_progression IEP
IEA
IAGP
protein:increased expression:endometrial stroma, cytoplasm (human)
DNA:snps:cds: (human)
MouseDO
RGD
PMID:9641239 PMID:8960147 RGD:13441555, RGD:13781876 NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,321
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit disease_progression IEP protein:increased expression:tumor:positive correlation between expression and tumor grade (P=0.027) RGD PMID:15800680 RGD:2290481 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
JBrowse link
G KISS1 KiSS-1 metastasis suppressor disease_progression IEP mRNA:decreased expression:endometrium RGD PMID:15949424 RGD:2302170 NCBI chr 1:204,190,341...204,196,491
Ensembl chr 1:204,190,341...204,196,491
JBrowse link
G KRAS KRAS proto-oncogene, GTPase IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:6320174 PMID:11745231 PMID:12460918 PMID:15696205 PMID:16361624 More... NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936
JBrowse link
G LOC112340386 Sharpr-MPRA regulatory region 11897 IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chr16:2,212,448...2,212,742 JBrowse link
G LOC112340387 Sharpr-MPRA regulatory region 5944 IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chr16:2,214,948...2,215,242 JBrowse link
G LOC116158483 CRISPRi-validated cis-regulatory element chr4.260 IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chr 4:1,784,888...1,786,262 JBrowse link
G MAPK1 mitogen-activated protein kinase 1 severity IEP protein:increased expression:endometrium (human)
protein:increased phosphorylation:endometrium (human)
RGD PMID:29081408 PMID:22459351 RGD:13702082, RGD:13441552 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 severity IEP protein:increased expression:endometrium (human)
protein:increased phosphorylation:endometrium (human)
RGD PMID:29081408 PMID:22459351 RGD:13702082, RGD:13441552 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MIR1225 microRNA 1225 IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chr16:2,090,195...2,090,284
Ensembl chr16:2,090,195...2,090,284
JBrowse link
G MIR152 microRNA 152 IDA
IEA
DNA:hypermethylation MouseDO
RGD
PMID:21327300 RGD:21066329 NCBI chr17:48,037,161...48,037,247
Ensembl chr17:48,037,161...48,037,247
JBrowse link
G MIR3180-5 microRNA 3180-5 IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chr16:2,135,977...2,136,129
Ensembl chr16:2,135,977...2,136,129
JBrowse link
G MIR3677 microRNA 3677 IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chr16:2,270,713...2,270,772
Ensembl chr16:2,270,713...2,270,772
JBrowse link
G MIR3677HG MIR3677 and MIR940 host gene IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chr16:2,268,663...2,273,072
Ensembl chr16:2,268,155...2,273,418
JBrowse link
G MIR4516 microRNA 4516 IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chr16:2,133,119...2,133,204
Ensembl chr16:2,133,119...2,133,204
JBrowse link
G MIR4717 microRNA 4717 IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chr16:2,274,620...2,274,691
Ensembl chr16:2,274,620...2,274,691
JBrowse link
G MIR6511B1 microRNA 6511b-1 IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chr16:2,106,669...2,106,753
Ensembl chr16:2,106,669...2,106,753
JBrowse link
G MIR940 microRNA 940 IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chr16:2,271,747...2,271,840
Ensembl chr16:2,271,747...2,271,840
JBrowse link
G MLH1 mutL homolog 1 IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:8566964 PMID:8574961 PMID:8592341 PMID:9526167 PMID:9697702 More... NCBI chr 3:36,993,466...37,050,846
Ensembl chr 3:36,993,350...37,050,846
JBrowse link
G MLH3 mutL homolog 3 IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:12702580 PMID:17656264 PMID:22290698 PMID:25741868 PMID:28492532 NCBI chr14:75,013,775...75,051,467
Ensembl chr14:75,013,769...75,051,532
JBrowse link
G MLST8 MTOR associated protein, LST8 homolog IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chr16:2,205,454...2,209,453
Ensembl chr16:2,204,248...2,209,453
JBrowse link
G MMP8 matrix metallopeptidase 8 IEP RGD PMID:10502722 RGD:2306086 NCBI chr11:102,711,796...102,724,954
Ensembl chr11:102,711,796...102,727,050
JBrowse link
G MMP9 matrix metallopeptidase 9 disease_progression IEP protein:increased expression:endometrium RGD PMID:12487935 RGD:2298523 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
JBrowse link
G MSH2 mutS homolog 2 IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:1586275 PMID:7585065 PMID:9536098 PMID:9718327 PMID:12115348 More... NCBI chr 2:47,403,067...47,634,501
Ensembl chr 2:47,403,067...47,663,146
JBrowse link
G MSH3 mutS homolog 3 IAGP
IEA
ClinVar Annotator: match by term: Endometrial carcinoma MouseDO
ClinVar
RGD
PMID:8782829 PMID:9536098 PMID:11470537 PMID:17576681 PMID:20981092 More... RGD:1600456 NCBI chr 5:80,654,652...80,876,815
Ensembl chr 5:80,654,652...80,876,815
JBrowse link
G MSH6 mutS homolog 6 IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:3195077 PMID:8063241 PMID:9536098 PMID:9774676 PMID:10471527 More... NCBI chr 2:47,783,145...47,806,953
Ensembl chr 2:47,695,530...47,810,063
JBrowse link
G MUTYH mutY DNA glycosylase IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:11818965 PMID:12606733 PMID:16140997 PMID:16338133 PMID:16492921 More... NCBI chr 1:45,329,242...45,340,440
Ensembl chr 1:45,329,163...45,340,893
JBrowse link
G NCOA1 nuclear receptor coactivator 1 IEP mRNA:increased expression:endometrium RGD PMID:14751175 RGD:2298984 NCBI chr 2:24,491,254...24,770,702
Ensembl chr 2:24,491,254...24,770,702
JBrowse link
G NCOR2 nuclear receptor corepressor 2 IEP mRNA:increased expression:endometrium RGD PMID:14751175 RGD:2298984 NCBI chr12:124,324,415...124,567,612
Ensembl chr12:124,324,415...124,567,612
JBrowse link
G NOS3 nitric oxide synthase 3 disease_progression IEP protein:increased expression:endometrium RGD PMID:9276029 RGD:2292090 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
JBrowse link
G PALB2 partner and localizer of BRCA2 IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:17200668 PMID:20091115 PMID:21285249 PMID:21365267 PMID:22241545 More... NCBI chr16:23,603,165...23,641,310
Ensembl chr16:23,603,160...23,641,321
JBrowse link
G PGP phosphoglycolate phosphatase IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chr16:2,211,593...2,214,840
Ensembl chr16:2,211,593...2,214,840
JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chr 3:179,148,126...179,240,093
Ensembl chr 3:179,148,114...179,240,093
JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 IAGP
IEA
DNA:mutations:multiple (human) MouseDO
RGD
PMID:23636398 RGD:13628733 NCBI chr 5:68,215,756...68,301,821
Ensembl chr 5:68,215,740...68,301,821
JBrowse link
G PKD1 polycystin 1, transient receptor potential channel interacting IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chr16:2,088,708...2,135,898
Ensembl chr16:2,088,708...2,135,898
JBrowse link
G PKD1-AS1 PKD1 antisense RNA 1 IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chr16:2,091,436...2,095,017
Ensembl chr16:2,091,436...2,095,433
JBrowse link
G PMS2 PMS1 homolog 2, mismatch repair system component IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:7628019 PMID:7704024 PMID:8072530 PMID:8993976 PMID:9683794 More... NCBI chr 7:5,970,925...6,009,106
Ensembl chr 7:5,970,925...6,009,130
JBrowse link
G POLD1 DNA polymerase delta 1, catalytic subunit IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:12376507 PMID:17145065 PMID:25529843 PMID:25741868 PMID:26467025 More... NCBI chr19:50,384,323...50,418,018
Ensembl chr19:50,384,204...50,418,018
JBrowse link
G POLE DNA polymerase epsilon, catalytic subunit IAGP
IEA
ClinVar Annotator: match by term: Endometrial carcinoma
DNA:mutations:multiple (human)
ClinVar
MouseDO
RGD
PMID:25741868 PMID:26467025 PMID:27217144 PMID:28492532 PMID:23528559 RGD:151347856 NCBI chr12:132,623,762...132,687,342
Ensembl chr12:132,623,753...132,687,376
JBrowse link
G PRKCA protein kinase C alpha IEP RGD PMID:11371124 RGD:2292462 NCBI chr17:66,302,613...66,810,743
Ensembl chr17:66,302,613...66,810,743
JBrowse link
G PTEN phosphatase and tensin homolog IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:1945792 PMID:7728760 PMID:8980400 PMID:9326929 PMID:9536098 More... NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930
JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 disease_progression IEP RGD PMID:18416056 RGD:2300125 NCBI chr 9:122,370,533...122,395,703
Ensembl chr 9:122,370,530...122,395,703
JBrowse link
G PTK2 protein tyrosine kinase 2 severity IEP protein:increased expression:endometrium RGD PMID:15536334 RGD:2292562 NCBI chr 8:140,657,900...141,002,079
Ensembl chr 8:140,657,900...141,002,216
JBrowse link
G RAB26 RAB26, member RAS oncogene family IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chr16:2,148,144...2,154,165
Ensembl chr16:2,140,803...2,154,165
JBrowse link
G RAD51C RAD51 paralog C IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:25741868 PMID:28492532 NCBI chr17:58,692,573...58,735,611
Ensembl chr17:58,692,573...58,735,611
JBrowse link
G RASSF1 Ras association domain family member 1 IDA
IEA
DNA, protein:hypermethylation, decreased expression:promoter, MouseDO
RGD
PMID:18469797 RGD:2299863 NCBI chr 3:50,329,788...50,340,836
Ensembl chr 3:50,329,782...50,340,980
JBrowse link
G RNPS1 RNA binding protein with serine rich domain 1 IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chr16:2,253,116...2,268,126
Ensembl chr16:2,253,116...2,268,397
JBrowse link
G RUNX3 RUNX family transcription factor 3 IAGP
IEA
DNA:promoter:hypermethylated MouseDO
RGD
PMID:18572225 RGD:2302555 NCBI chr 1:24,899,511...24,965,138
Ensembl chr 1:24,899,511...24,965,121
JBrowse link
G SFN stratifin IEP RGD PMID:16271083 RGD:2299931 NCBI chr 1:26,863,149...26,864,456
Ensembl chr 1:26,863,149...26,864,456
JBrowse link
G SMAD4 SMAD family member 4 severity IAGP
IEA
IEP
DNA:substitutions:promoter
mRNA:decreased expression:endometrium
MouseDO
RGD
PMID:10331746 PMID:15385128 RGD:2300009, RGD:2299966 NCBI chr18:51,030,213...51,085,042
Ensembl chr18:51,028,394...51,085,045
JBrowse link
G SNHG19 small nucleolar RNA host gene 19 IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chr16:2,154,782...2,155,358
Ensembl chr16:2,154,792...2,155,405
JBrowse link
G SNORD60 small nucleolar RNA, C/D box 60 IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chr16:2,155,023...2,155,105
Ensembl chr16:2,155,023...2,155,105
JBrowse link
G SPARC secreted protein acidic and cysteine rich IDA
IEA
DNA, mRNA, protein:hypermethylation, altered expression MouseDO
RGD
PMID:17487382 RGD:2300020 NCBI chr 5:151,661,096...151,686,915
Ensembl chr 5:151,661,096...151,686,975
JBrowse link
G STK11 serine/threonine kinase 11 IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar PMID:25741868 PMID:26467025 PMID:28492532 NCBI chr19:1,205,778...1,228,431
Ensembl chr19:1,177,558...1,228,431
JBrowse link
G TACC3 transforming acidic coiled-coil containing protein 3 IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chr 4:1,721,521...1,745,171
Ensembl chr 4:1,712,858...1,745,171
JBrowse link
G TFF1 trefoil factor 1 disease_progression IEP protein:increased expression:endometrium RGD PMID:9221798 RGD:2298572 NCBI chr21:42,362,282...42,366,535
Ensembl chr21:42,362,282...42,366,535
JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 disease_progression IEP protein:increased expression:endometrium RGD PMID:12487935 RGD:2298523 NCBI chr  X:47,582,436...47,586,789
Ensembl chr  X:47,582,408...47,586,789
JBrowse link
G TIMP2 TIMP metallopeptidase inhibitor 2 disease_progression IEP mRNA:decreased expression:endometrium RGD PMID:17009991 RGD:2290360 NCBI chr17:78,852,977...78,925,387
Ensembl chr17:78,852,977...78,925,387
JBrowse link
G TIMP4 TIMP metallopeptidase inhibitor 4 disease_progression IEP protein:increased expression:endometrium RGD PMID:12798711 RGD:2290420 NCBI chr 3:12,153,068...12,158,912
Ensembl chr 3:12,153,068...12,158,912
JBrowse link
G TP53 tumor protein p53 severity IEP
IAGP
ISO
protein:increased expression:epithelial cell, endometrium
ClinVar Annotator: match by term: Endometrial carcinoma
DNA:mutations: :
ClinVar
RGD
PMID:25741868 PMID:28492532 PMID:18431720 PMID:26353976 RGD:2298525, RGD:11075084 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G TRAF7 TNF receptor associated factor 7 IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chr16:2,155,782...2,178,129
Ensembl chr16:2,155,698...2,178,129
JBrowse link
G TSC2 TSC complex subunit 2 IAGP ClinVar Annotator: match by term: Endometrial carcinoma ClinVar NCBI chr16:2,047,985...2,089,491
Ensembl chr16:2,047,967...2,089,491
JBrowse link
G WNT2 Wnt family member 2 IEP mRNA:decreased expression:endometrium RGD PMID:9099960 RGD:2291875 NCBI chr 7:117,275,451...117,323,058
Ensembl chr 7:117,275,451...117,323,152
JBrowse link
G WNT3 Wnt family member 3 IEP mRNA:decreased expression:tumor:vs normal endometrium RGD PMID:9099960 RGD:2291875 NCBI chr17:46,830,790...46,833,102
Ensembl chr17:46,762,506...46,833,154
JBrowse link
G WNT4 Wnt family member 4 IEP mRNA:decreased expression:tumor:vs normal endometrium RGD PMID:9099960 RGD:2291875 NCBI chr 1:22,117,313...22,143,097
Ensembl chr 1:22,117,313...22,143,969
JBrowse link
G WNT5A Wnt family member 5A IEP mRNA:decreased expression:tumor:vs normal endometrium RGD PMID:9099960 RGD:2291875 NCBI chr 3:55,465,715...55,505,263
Ensembl chr 3:55,465,715...55,490,539
JBrowse link
endometrial hyperplasia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BIRC5 baculoviral IAP repeat containing 5 IEP protein:increased expression:endometrium RGD PMID:16803539 RGD:2298940 NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636
JBrowse link
G CA9 carbonic anhydrase 9 IEP protein:altered localization:membrane, endometrium RGD PMID:17452774 RGD:2298945 NCBI chr 9:35,673,928...35,681,159
Ensembl chr 9:35,673,928...35,681,159
JBrowse link
G CDC25B cell division cycle 25B IEP protein:increased expression:endometrium RGD PMID:14559803 RGD:4105451 NCBI chr20:3,786,951...3,806,115
Ensembl chr20:3,786,772...3,806,121
JBrowse link
G CDC25C cell division cycle 25C IEP RGD PMID:12931023 RGD:4105452 NCBI chr 5:138,285,265...138,338,355
Ensembl chr 5:138,285,269...138,338,355
JBrowse link
G CDKN1C cyclin dependent kinase inhibitor 1C EXP CTD Direct Evidence: marker/mechanism CTD PMID:22064387 NCBI chr11:2,883,218...2,885,775
Ensembl chr11:2,883,213...2,885,775
JBrowse link
G CELSR2 cadherin EGF LAG seven-pass G-type receptor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22248470 NCBI chr 1:109,249,539...109,275,751
Ensembl chr 1:109,249,539...109,275,751
JBrowse link
G CSRP1 cysteine and glycine rich protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22248470 NCBI chr 1:201,483,530...201,507,123
Ensembl chr 1:201,483,530...201,509,456
JBrowse link
G DDX1 DEAD-box helicase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22248470 NCBI chr 2:15,591,868...15,631,101
Ensembl chr 2:15,591,178...15,634,346
JBrowse link
G H19 H19 imprinted maternally expressed transcript IEP mRNA:altered localization:endometrium RGD PMID:15228427 RGD:2306178 NCBI chr11:1,995,176...2,001,466
Ensembl chr11:1,995,166...2,001,470
JBrowse link
G JUP junction plakoglobin IEP protein:decreased expression:endometrium RGD PMID:12635138 RGD:2301747 NCBI chr17:41,754,609...41,786,711
Ensembl chr17:41,754,604...41,786,931
JBrowse link
G KRAS KRAS proto-oncogene, GTPase IAGP
IEA
MouseDO
RGD
PMID:19419940 RGD:2314912 NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936
JBrowse link
G MMP7 matrix metallopeptidase 7 IEP protein:increased expression:endometrium RGD PMID:17352221 RGD:2298522 NCBI chr11:102,520,508...102,530,747
Ensembl chr11:102,520,508...102,530,750
JBrowse link
G PTEN phosphatase and tensin homolog EXP CTD Direct Evidence: marker/mechanism CTD PMID:16402032 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930
JBrowse link
G PTK2 protein tyrosine kinase 2 IEP protein:increased expression:endometrium RGD PMID:15536334 RGD:2292562 NCBI chr 8:140,657,900...141,002,079
Ensembl chr 8:140,657,900...141,002,216
JBrowse link
G SKP2 S-phase kinase associated protein 2 IEP associated with Endometrial Neoplasms;protein:increased expression:endometrium RGD PMID:16080017 RGD:2315043 NCBI chr 5:36,152,111...36,193,530
Ensembl chr 5:36,151,989...36,196,849
JBrowse link
G TFF1 trefoil factor 1 IEP protein:increased expression:endometrium RGD PMID:9221798 RGD:2298572 NCBI chr21:42,362,282...42,366,535
Ensembl chr21:42,362,282...42,366,535
JBrowse link
Endometrial Neoplasms term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC9 ATP binding cassette subfamily C member 9 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23104009 NCBI chr12:21,797,389...21,941,426
Ensembl chr12:21,797,389...21,942,543
JBrowse link
G AKR1B1 aldo-keto reductase family 1 member B EXP CTD Direct Evidence: marker/mechanism CTD PMID:23146748 NCBI chr 7:134,442,350...134,459,239
Ensembl chr 7:134,442,356...134,459,284
JBrowse link
G AKR1B10 aldo-keto reductase family 1 member B10 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23146748 NCBI chr 7:134,527,567...134,541,412
Ensembl chr 7:134,527,567...134,541,412
JBrowse link
G AKR1C1 aldo-keto reductase family 1 member C1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16338060 NCBI chr10:4,963,415...4,983,283
Ensembl chr10:4,963,253...4,983,283
JBrowse link
G AKR1C3 aldo-keto reductase family 1 member C3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16338060 NCBI chr10:5,048,781...5,107,686
Ensembl chr10:5,035,354...5,107,686
JBrowse link
G AMHR2 anti-Mullerian hormone receptor type 2 IEP protein:increased expression:endometrium RGD PMID:17988723 RGD:2315651 NCBI chr12:53,423,855...53,431,672
Ensembl chr12:53,423,855...53,431,672
JBrowse link
G APC APC regulator of WNT signaling pathway ISO RGD PMID:24474556 RGD:13524584 NCBI chr 5:112,707,498...112,846,239
Ensembl chr 5:112,707,498...112,846,239
JBrowse link
G ARID1A AT-rich interaction domain 1A EXP CTD Direct Evidence: marker/mechanism CTD PMID:23104009 NCBI chr 1:26,696,015...26,782,104
Ensembl chr 1:26,693,236...26,782,104
JBrowse link
G ATR ATR serine/threonine kinase IAGP ClinVar Annotator: match by term: Endometrial neoplasm ClinVar PMID:19470935 PMID:21228398 PMID:23144622 PMID:28492532 NCBI chr 3:142,449,235...142,578,733
Ensembl chr 3:142,449,007...142,578,733
JBrowse link
G BCL2 BCL2 apoptosis regulator severity IEP RGD PMID:18386458 RGD:2298890 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19363521 NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636
JBrowse link
G CALB2 calbindin 2 IEP protein:decreased expression:endometrium RGD PMID:18604736 RGD:2315881 NCBI chr16:71,358,723...71,390,433
Ensembl chr16:71,358,713...71,390,436
JBrowse link
G CCL2 C-C motif chemokine ligand 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17380299 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
JBrowse link
G CCND1 cyclin D1 IEP
EXP
protein:increased expression:endometrium
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:29232554 PMID:18306533 RGD:2296034 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
JBrowse link
G CD44 CD44 molecule (Indian blood group) disease_progression IEP
IDA
protein:decreased expression:endometrium
mRNA, protein:splice variant, increased expression:endometrium
RGD PMID:14658589 PMID:16308159 RGD:2296044, RGD:2289358 NCBI chr11:35,139,171...35,232,402
Ensembl chr11:35,138,882...35,232,402
JBrowse link
G CD46 CD46 molecule IEP protein:increased expression:tumor:versus benign endometrium (p<0.0001) RGD PMID:10637067 RGD:2293548 NCBI chr 1:207,752,038...207,795,516
Ensembl chr 1:207,752,037...207,795,513
JBrowse link
G CDH1 cadherin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:8075649 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537
JBrowse link
G CDK2 cyclin dependent kinase 2 disease_progression IEP protein:increased expression:endometrium RGD PMID:17483252 RGD:2289230 NCBI chr12:55,966,830...55,972,789
Ensembl chr12:55,966,781...55,972,789
JBrowse link
G CDK4 cyclin dependent kinase 4 disease_progression IEP protein:increased expression:endometrium RGD PMID:14648178 RGD:2299055 NCBI chr12:57,747,727...57,752,310
Ensembl chr12:57,747,727...57,756,013
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A susceptibility IAGP
IEP
DNA:polymorphism:cds:p.S31R
protein:increased expression:endometrium
RGD PMID:15099969 PMID:16837908 RGD:2296047, RGD:2289683 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337
JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B IEP protein:decreased expression:endometrium RGD PMID:15188025 RGD:2299090 NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,369
JBrowse link
G CDKN1C cyclin dependent kinase inhibitor 1C EXP CTD Direct Evidence: marker/mechanism CTD PMID:22064387 NCBI chr11:2,883,218...2,885,775
Ensembl chr11:2,883,213...2,885,775
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A severity IEP protein:increased expression:endometrium RGD PMID:16837908 RGD:2289683 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301
JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B IAGP DNA:SNPs: :rs615552, rs573687 (human) RGD PMID:23361049 RGD:7248756 NCBI chr 9:22,002,903...22,009,313
Ensembl chr 9:22,002,903...22,009,305
JBrowse link
G CHD4 chromodomain helicase DNA binding protein 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23104009 NCBI chr12:6,570,082...6,607,379
Ensembl chr12:6,570,082...6,614,524
JBrowse link
G CHFR checkpoint with forkhead and ring finger domains EXP CTD Direct Evidence: marker/mechanism CTD PMID:17143476 NCBI chr12:132,832,356...132,887,618
Ensembl chr12:132,822,187...132,956,304
JBrowse link
G CNR1 cannabinoid receptor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29805589 PMID:32751388 NCBI chr 6:88,139,864...88,167,349
Ensembl chr 6:88,139,864...88,166,347
JBrowse link
G CNR2 cannabinoid receptor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29805589 NCBI chr 1:23,870,515...23,913,362
Ensembl chr 1:23,870,515...23,913,362
JBrowse link
G CTNNA1 catenin alpha 1 disease_progression IEP RGD PMID:16803534 RGD:2298485 NCBI chr 5:138,753,425...138,935,034
Ensembl chr 5:138,610,967...138,935,034
JBrowse link
G CTNNB1 catenin beta 1 disease_progression TAS
IAGP
IEP
ClinVar Annotator: match by term: Endometrial neoplasm
protein:increased expression:nucleus
ClinVar
RGD
PMID:9065402 PMID:9294210 PMID:10192393 PMID:25157968 PMID:25741868 More... RGD:4143515, RGD:2289828, RGD:2298485 NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17380299 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716
JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23200943 NCBI chr15:74,337,762...74,367,646
Ensembl chr15:74,337,759...74,367,646
JBrowse link
G DCN decorin EXP CTD Direct Evidence: marker/mechanism CTD PMID:16804899 NCBI chr12:91,140,484...91,182,817
Ensembl chr12:91,140,484...91,183,217
JBrowse link
G DNMT1 DNA methyltransferase 1 IEP mRNA,protein:decreased expression:uterus: RGD PMID:15721400 RGD:9588596 NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286
JBrowse link
G DNMT3B DNA methyltransferase 3 beta IEP mRNA,protein:decreased expression:uterus: RGD PMID:15721400 RGD:9588596 NCBI chr20:32,762,385...32,809,356
Ensembl chr20:32,762,385...32,809,359
JBrowse link
G EGF epidermal growth factor severity IEP protein:increased expression:plasma (human) RGD PMID:25416211 RGD:13432197 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766
JBrowse link
G EP300 E1A binding protein p300 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23104009 NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,592...41,180,077
JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 severity
disease_progression
IAGP
TAS
IEP
DNA:amplification RGD PMID:17945336 PMID:19078924 PMID:18202752 RGD:2298491, RGD:4143515, RGD:2298490 NCBI chr17:39,688,094...39,728,658
Ensembl chr17:39,687,914...39,730,426
JBrowse link
G ERBB3 erb-b2 receptor tyrosine kinase 3 IEP protein:increased expression:endometrium RGD PMID:10537356 RGD:2298505 NCBI chr12:56,080,108...56,103,505
Ensembl chr12:56,076,799...56,103,505
JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 IEP protein:increased expression:endometrium RGD PMID:10537356 RGD:2298505 NCBI chr 2:211,375,717...212,538,802
Ensembl chr 2:211,375,717...212,538,841
JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit susceptibility IAGP DNA:polymorphism:exon:p.R156R(human) RGD PMID:26349749 RGD:12880439 NCBI chr19:45,349,837...45,370,573
Ensembl chr19:45,349,837...45,370,918
JBrowse link
G ESR1 estrogen receptor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24185510 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619
JBrowse link
G ESR2 estrogen receptor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25437045 NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112
JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:21903722 NCBI chr 7:148,807,383...148,884,291
Ensembl chr 7:148,807,257...148,884,321
JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23104009 NCBI chr 4:152,320,544...152,536,092
Ensembl chr 4:152,320,544...152,536,092
JBrowse link
G FGFR2 fibroblast growth factor receptor 2 susceptibility IAGP
EXP
DNA:mutations
ClinVar Annotator: match by term: Endometrial neoplasm
CTD Direct Evidence: marker/mechanism
DNA:SNP
ClinVar
CTD
RGD
PMID:7719344 PMID:8651276 PMID:8696350 PMID:9462761 PMID:9719378 More... RGD:2301189, RGD:2301188 NCBI chr10:121,478,330...121,598,458
Ensembl chr10:121,478,332...121,598,458
JBrowse link
G FHIT fragile histidine triad diadenosine triphosphatase IEP protein:decreased expression:endometrium:loss of expression in 41/111 (37%) of tumors, significantly associated with poor survival and/or poor prognostic indicators RGD PMID:10873085 RGD:2289899 NCBI chr 3:59,747,277...61,251,452
Ensembl chr 3:59,747,277...61,251,459
JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 severity
disease_progression
IEP mRNA, protein:increased expression:endometrium RGD PMID:12485477 PMID:10831352 RGD:2301252, RGD:2301256 NCBI chr13:28,300,346...28,495,128
Ensembl chr13:28,300,346...28,495,145
JBrowse link
G GSK3B glycogen synthase kinase 3 beta treatment IMP human cells in a mouse xenograft model RGD PMID:23941783 RGD:13441554 NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994
JBrowse link
G HDAC1 histone deacetylase 1 disease_progression IEP RGD PMID:18714364 RGD:2306205 NCBI chr 1:32,292,083...32,333,626
Ensembl chr 1:32,292,083...32,333,635
JBrowse link
G HDAC2 histone deacetylase 2 disease_progression IEP RGD PMID:18714364 RGD:2306205 NCBI chr 6:113,933,028...113,971,148
Ensembl chr 6:113,933,028...114,011,308
JBrowse link
G HOXA10 homeobox A10 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21670700 NCBI chr 7:27,170,605...27,179,861
Ensembl chr 7:27,170,605...27,180,261
JBrowse link
G HOXA11 homeobox A11 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16804899 NCBI chr 7:27,181,157...27,185,232
Ensembl chr 7:27,181,157...27,185,232
JBrowse link
G HSD17B2 hydroxysteroid 17-beta dehydrogenase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23200943 NCBI chr16:82,035,253...82,098,534
Ensembl chr16:82,035,004...82,098,534
JBrowse link
G IGF1R insulin like growth factor 1 receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:21442237 NCBI chr15:98,648,539...98,964,530
Ensembl chr15:98,648,539...98,964,530
JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 IEP protein:decreased expression:plasma:significantly lower circulating levels in 80 cases vs 80 controls (p<0.001), significantly decreased risk in the highest quartile of expression RGD PMID:15159305 RGD:2290018 NCBI chr 7:45,912,245...45,921,272
Ensembl chr 7:45,912,245...45,921,874
JBrowse link
G INHA inhibin subunit alpha IEP mRNA:decreased expression:endometrium RGD PMID:15745937 RGD:1579943 NCBI chr 2:219,572,310...219,575,711
Ensembl chr 2:219,569,162...219,575,711
JBrowse link
G JAG1 jagged canonical Notch ligand 1 IEP RGD PMID:18691378 RGD:2299152 NCBI chr20:10,637,684...10,673,999
Ensembl chr20:10,637,684...10,673,999
JBrowse link
G JAZF1 JAZF zinc finger 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18264096 NCBI chr 7:27,830,577...28,180,795
Ensembl chr 7:27,830,573...28,180,795
JBrowse link
G KDR kinase insert domain receptor disease_progression IEP mRNA:increased expression:endometrium RGD PMID:12485477 PMID:11745191 RGD:2301252, RGD:2301760 NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595
JBrowse link
G KRAS KRAS proto-oncogene, GTPase TAS
IAGP
RGD PMID:19078924 PMID:19960433 RGD:4143515, RGD:2314907 NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936
JBrowse link
G LASP1 LIM and SH3 protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28232485 NCBI chr17:38,870,058...38,921,770
Ensembl chr17:38,869,859...38,921,770
JBrowse link
G LNPEP leucyl and cystinyl aminopeptidase IEP RGD PMID:15491750 RGD:2314921 NCBI chr 5:96,936,080...97,037,513
Ensembl chr 5:96,935,394...97,037,513
JBrowse link
G MAP3K4 mitogen-activated protein kinase kinase kinase 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23104009 NCBI chr 6:160,991,769...161,117,380
Ensembl chr 6:160,991,727...161,117,385
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 treatment IDA RGD PMID:24917306 RGD:13441559 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase ISO DNA:amplification RGD PMID:11719459 RGD:70557 NCBI chr 7:116,672,196...116,798,377
Ensembl chr 7:116,672,196...116,798,377
JBrowse link
G MIR200C microRNA 200c EXP CTD Direct Evidence: marker/mechanism CTD PMID:22569286 NCBI chr12:6,963,699...6,963,766
Ensembl chr12:6,963,699...6,963,766
JBrowse link
G MLH1 mutL homolog 1 TAS RGD PMID:19078924 RGD:4143515 NCBI chr 3:36,993,466...37,050,846
Ensembl chr 3:36,993,350...37,050,846
JBrowse link
G MLH3 mutL homolog 3 EXP CTD Direct Evidence: marker/mechanism CTD NCBI chr14:75,013,775...75,051,467
Ensembl chr14:75,013,769...75,051,532
JBrowse link
G MMP2 matrix metallopeptidase 2 disease_progression IEP protein:increased expression:endometrium RGD PMID:17009991 RGD:2290360 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
JBrowse link
G MSH2 mutS homolog 2 IAGP
IEP
DNA, protein:mutation, decreased expression:endometrium RGD PMID:17925543 PMID:11920468 RGD:2298951, RGD:2293523 NCBI chr 2:47,403,067...47,634,501
Ensembl chr 2:47,403,067...47,663,146
JBrowse link
G MSH3 mutS homolog 3 EXP CTD Direct Evidence: marker/mechanism CTD NCBI chr 5:80,654,652...80,876,815
Ensembl chr 5:80,654,652...80,876,815
JBrowse link
G MSH6 mutS homolog 6 TAS
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:10508506 PMID:19078924 RGD:4143515 NCBI chr 2:47,783,145...47,806,953
Ensembl chr 2:47,695,530...47,810,063
JBrowse link
G MTHFR methylenetetrahydrofolate reductase EXP CTD Direct Evidence: marker/mechanism CTD PMID:17301261 NCBI chr 1:11,785,723...11,805,964
Ensembl chr 1:11,785,723...11,806,455
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:26656844 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
JBrowse link
G NCAPG non-SMC condensin I complex subunit G EXP CTD Direct Evidence: marker/mechanism CTD PMID:34480403 NCBI chr 4:17,810,979...17,844,865
Ensembl chr 4:17,810,979...17,844,865
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20530669 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
JBrowse link
G NRIP1 nuclear receptor interacting protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27348297 NCBI chr21:14,961,235...15,065,936
Ensembl chr21:14,961,235...15,065,936
JBrowse link
G OGG1 8-oxoguanine DNA glycosylase no_association IAGP DNA:mutation:exon:p.S326C (1245C>G, rs1052133) (human) RGD PMID:22271435 PMID:22544315 RGD:8657377, RGD:8657379 NCBI chr 3:9,749,952...9,783,108
Ensembl chr 3:9,749,944...9,788,219
JBrowse link
G PAWR pro-apoptotic WT1 regulator EXP CTD Direct Evidence: marker/mechanism CTD PMID:15877079 NCBI chr12:79,584,879...79,690,964
Ensembl chr12:79,574,979...79,690,964
JBrowse link
G PGR progesterone receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:23200943 NCBI chr11:101,029,624...101,129,813
Ensembl chr11:101,029,624...101,129,813
JBrowse link
G PHB1 prohibitin 1 IEP protein:increased expression:endometrium RGD PMID:10421803 RGD:2292406 NCBI chr17:49,404,052...49,414,882
Ensembl chr17:49,404,049...49,414,905
JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha TAS RGD PMID:19078924 RGD:4143515 NCBI chr 3:179,148,126...179,240,093
Ensembl chr 3:179,148,114...179,240,093
JBrowse link
G PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta IEP mRNA:increased expression:endometrium (human) RGD PMID:17427168 RGD:13441594 NCBI chr 3:138,652,698...138,834,928
Ensembl chr 3:138,652,698...138,834,928
JBrowse link
G PLXNA3 plexin A3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21933904 NCBI chr  X:154,458,281...154,477,779
Ensembl chr  X:154,458,281...154,477,779
JBrowse link
G POLD1 DNA polymerase delta 1, catalytic subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:23263490 NCBI chr19:50,384,323...50,418,018
Ensembl chr19:50,384,204...50,418,018
JBrowse link
G PTEN phosphatase and tensin homolog severity IEP
TAS
IAGP
EXP
protein:decreased expression:endometrium
DNA:loss of heterozygosity:cds: (human)
DNA:mutations:multiple (human)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:9326929 PMID:12888921 PMID:16402032 PMID:16804899 PMID:17317031 More... RGD:2292506, RGD:4143515, RGD:12832746, RGD:12832753 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 disease_progression IEP RGD PMID:18416056 RGD:2300125 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G RB1 RB transcriptional corepressor 1 IEP RGD PMID:14648178 RGD:2299055 NCBI chr13:48,303,751...48,481,890
Ensembl chr13:48,303,744...48,599,436
JBrowse link
G RNF144B ring finger protein 144B EXP CTD Direct Evidence: marker/mechanism CTD PMID:29724995 NCBI chr 6:18,387,350...18,468,870
Ensembl chr 6:18,387,350...18,468,870
JBrowse link
G RNF43 ring finger protein 43 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25344691 NCBI chr17:58,352,500...58,417,534
Ensembl chr17:58,353,676...58,417,595
JBrowse link
G SEMA3B semaphorin 3B EXP CTD Direct Evidence: marker/mechanism CTD PMID:21933904 NCBI chr 3:50,267,652...50,277,546
Ensembl chr 3:50,267,558...50,277,546
JBrowse link
G SEMA3F semaphorin 3F EXP CTD Direct Evidence: marker/mechanism CTD PMID:21933904 NCBI chr 3:50,155,058...50,189,075
Ensembl chr 3:50,155,045...50,189,075
JBrowse link
G SIX1 SIX homeobox 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27259717 NCBI chr14:60,643,421...60,649,477
Ensembl chr14:60,643,421...60,658,259
JBrowse link
G SKP2 S-phase kinase associated protein 2 IEP RGD PMID:15220466 RGD:2315045 NCBI chr 5:36,152,111...36,193,530
Ensembl chr 5:36,151,989...36,196,849
JBrowse link
G SOCS3 suppressor of cytokine signaling 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16804899 NCBI chr17:78,356,778...78,360,925
Ensembl chr17:78,356,778...78,360,077
JBrowse link
G SPINK1 serine peptidase inhibitor Kazal type 1 IEP RGD PMID:9891532 RGD:2300389 NCBI chr 5:147,824,582...147,839,196
Ensembl chr 5:147,824,572...147,831,671
JBrowse link
G SPOP speckle type BTB/POZ protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:23104009 NCBI chr17:49,598,884...49,678,163
Ensembl chr17:49,598,884...49,678,163
JBrowse link
G SRD5A2 steroid 5 alpha-reductase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23200943 NCBI chr 2:31,522,480...31,663,009
Ensembl chr 2:31,522,480...31,580,938
JBrowse link
G SRSF10 serine and arginine rich splicing factor 10 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21072693 NCBI chr 1:23,964,347...23,980,327
Ensembl chr 1:23,964,347...23,980,927
JBrowse link
G ST14 ST14 transmembrane serine protease matriptase disease_progression IEP protein:increased expression:endometrium RGD PMID:19443387 RGD:2315087 NCBI chr11:130,159,782...130,210,362
Ensembl chr11:130,159,782...130,210,362
JBrowse link
G STAR steroidogenic acute regulatory protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:23200943 NCBI chr 8:38,142,700...38,150,952
Ensembl chr 8:38,142,700...38,150,992
JBrowse link
G STAT3 signal transducer and activator of transcription 3 IEP protein:increased tyrosine phosphorylation:endometrium RGD PMID:17311011 RGD:1643476 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,540
JBrowse link
G SULT1A1 sulfotransferase family 1A member 1 no_association IAGP DNA:SNP::no difference in allele distribution or genotype between patients and controls
DNA:SNP:CDS, 3'-UTR:rs9282861, rs6839 and rs1042157, alone or in combination with each other, also rs9282861 (GA + AA) combined with CYP1A1 SNP rs4646903 (TT) or with SULT1E1 SNP rs3736599 (GA+AA)
RGD PMID:18497059 PMID:18318428 RGD:2301045, RGD:2301040 NCBI chr16:28,605,258...28,623,375
Ensembl chr16:28,605,196...28,614,279
JBrowse link
G SULT2B1 sulfotransferase family 2B member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25437045 NCBI chr19:48,552,172...48,599,427
Ensembl chr19:48,552,172...48,599,425
JBrowse link
G SUZ12 SUZ12 polycomb repressive complex 2 subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:18264096 NCBI chr17:31,937,007...32,001,038
Ensembl chr17:31,937,007...32,001,038
JBrowse link
G TERT telomerase reverse transcriptase IEP mRNA:increased expression:endometrium RGD PMID:11078809 RGD:2298562 NCBI chr 5:1,253,167...1,295,068
Ensembl chr 5:1,253,147...1,295,068
JBrowse link
G TIMP3 TIMP metallopeptidase inhibitor 3 disease_progression IEP protein:increased expression:endometrium RGD PMID:12798711 RGD:2290420 NCBI chr22:32,801,705...32,863,041
Ensembl chr22:32,801,705...32,863,041
JBrowse link
G TNFSF10 TNF superfamily member 10 EXP CTD Direct Evidence: therapeutic CTD PMID:20071162 NCBI chr 3:172,505,508...172,523,430
Ensembl chr 3:172,505,508...172,523,475
JBrowse link
G TP53 tumor protein p53 TAS
ISO
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:7955072 PMID:19078924 RGD:4143515 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G TP73 tumor protein p73 susceptibility IAGP DNA:hypermethylation
DNA:polymorphism:exon
RGD PMID:16928264 PMID:15723718 RGD:2290585, RGD:2298528 NCBI chr 1:3,652,516...3,736,201
Ensembl chr 1:3,652,516...3,736,201
JBrowse link
G TRPV1 transient receptor potential cation channel subfamily V member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:32751388 NCBI chr17:3,565,446...3,609,411
Ensembl chr17:3,565,444...3,609,411
JBrowse link
G TRPV2 transient receptor potential cation channel subfamily V member 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:32751388 NCBI chr17:16,415,571...16,437,003
Ensembl chr17:16,415,571...16,437,003
JBrowse link
G TSPYL2 TSPY like 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23104009 NCBI chr  X:53,082,367...53,088,540
Ensembl chr  X:53,082,367...53,088,540
JBrowse link
G VEGFA vascular endothelial growth factor A EXP CTD Direct Evidence: marker/mechanism CTD PMID:17380299 NCBI chr 6:43,770,209...43,786,487
Ensembl chr 6:43,770,184...43,786,487
JBrowse link
G ZEB1 zinc finger E-box binding homeobox 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18622689 NCBI chr10:31,318,417...31,529,804
Ensembl chr10:31,318,495...31,529,814
JBrowse link
endometrial serous adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATM ATM serine/threonine kinase IAGP ClinVar Annotator: match by term: Endometrial serous adenocarcinoma ClinVar NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,223,044...108,369,102
JBrowse link
G BRCA2 BRCA2 DNA repair associated susceptibility IAGP
IEA
DNA:deletion: :6174delT MouseDO
RGD
PMID:16650962 RGD:2289045 NCBI chr13:32,315,508...32,400,268
Ensembl chr13:32,315,086...32,400,268
JBrowse link
endometrial stromal sarcoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KIT KIT proto-oncogene, receptor tyrosine kinase IEP protein:increased expression:tumor:increased in 6/8 (75%) of tumors RGD PMID:17367465 RGD:2292170 NCBI chr 4:54,657,957...54,740,715
Ensembl chr 4:54,657,267...54,740,783
JBrowse link
Endometrioid Carcinomas term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 IAGP ClinVar Annotator: match by term: Endometrial Endometrioid Adenocarcinoma, Variant with Squamous Differentiation ClinVar PMID:17611497 PMID:18256540 PMID:18392055 PMID:18504432 PMID:18611285 More... NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751
JBrowse link
G APC APC regulator of WNT signaling pathway IEP
IAGP
mRNA, protein:decreased expression:endometrium (human)
DNA:hypermethylation: (human)
RGD PMID:18570730 PMID:18570730 RGD:13432144, RGD:13432144 NCBI chr 5:112,707,498...112,846,239
Ensembl chr 5:112,707,498...112,846,239
JBrowse link
G AREG amphiregulin IEP mRNA, protein:increased expression:endometrium RGD PMID:16962163 RGD:2289950 NCBI chr 4:74,445,136...74,455,005
Ensembl chr 4:74,445,136...74,455,005
JBrowse link
G ATP7B ATPase copper transporting beta disease_progression IEP protein:increased expression:endometrium RGD PMID:15790435 RGD:2298864 NCBI chr13:51,932,669...52,012,132
Ensembl chr13:51,930,436...52,012,125
JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 IEP protein:increased expression:endometrium RGD PMID:16803539 RGD:2298940 NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636
JBrowse link
G BMP4 bone morphogenetic protein 4 IEP RGD PMID:12782598 RGD:2296026 NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761
JBrowse link
G CA9 carbonic anhydrase 9 IEP protein:altered localization:membrane, endometrium RGD PMID:17452774 RGD:2298945 NCBI chr 9:35,673,928...35,681,159
Ensembl chr 9:35,673,928...35,681,159
JBrowse link
G CCNE1 cyclin E1 IEP protein:increased expression:endometrium RGD PMID:17483252 RGD:2289230 NCBI chr19:29,811,991...29,824,312
Ensembl chr19:29,811,991...29,824,312
JBrowse link
G CDH1 cadherin 1 IEP protein:decreased expression:endometrium RGD PMID:18295959 RGD:2296045 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537
JBrowse link
G CDK2 cyclin dependent kinase 2 severity IEP RGD PMID:9673386 RGD:2298990 NCBI chr12:55,966,830...55,972,789
Ensembl chr12:55,966,781...55,972,789
JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B IEP RGD PMID:17985331 RGD:2299091 NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,369
JBrowse link
G CHEK2 checkpoint kinase 2 susceptibility IAGP RGD PMID:17164260 RGD:2293868 NCBI chr22:28,687,743...28,741,834
Ensembl chr22:28,687,743...28,742,422
JBrowse link
G CTNNB1 catenin beta 1 IAGP DNA:mutations RGD PMID:17418409 RGD:2289817 NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096
JBrowse link
G DAXX death domain associated protein IEP protein:increased expression:ovary: RGD PMID:23539629 RGD:9587820 NCBI chr 6:33,318,558...33,322,959
Ensembl chr 6:33,318,558...33,323,016
JBrowse link
G DNMT1 DNA methyltransferase 1 IEP mRNA,protein:increased expression:uterus: RGD PMID:15721400 RGD:9588596 NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286
JBrowse link
G DNMT3B DNA methyltransferase 3 beta IEP mRNA,protein:increased expression:uterus: RGD PMID:15721400 RGD:9588596 NCBI chr20:32,762,385...32,809,356
Ensembl chr20:32,762,385...32,809,359
JBrowse link
G EGFR epidermal growth factor receptor IEP
IAGP
mRNA:decreased expression:endometrium
ClinVar Annotator: match by term: Endometrial Endometrioid Adenocarcinoma, Variant with Squamous Differentiation
ClinVar
RGD
PMID:22885469 PMID:16962163 RGD:2289950 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
JBrowse link
G ENO2 enolase 2 IEP RGD PMID:18156975 RGD:2293737 NCBI chr12:6,914,580...6,923,697
Ensembl chr12:6,913,745...6,923,698
JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 IEP RGD PMID:16962163 RGD:2289950 NCBI chr17:39,688,094...39,728,658
Ensembl chr17:39,687,914...39,730,426
JBrowse link
G ERBB3 erb-b2 receptor tyrosine kinase 3 IEP RGD PMID:16962163 RGD:2289950 NCBI chr12:56,080,108...56,103,505
Ensembl chr12:56,076,799...56,103,505
JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 IEP RGD PMID:16962163 RGD:2289950 NCBI chr 2:211,375,717...212,538,802
Ensembl chr 2:211,375,717...212,538,841
JBrowse link
G ESR1 estrogen receptor 1 severity IEP protein:increased phosphorylation RGD PMID:14559803 RGD:4105451 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619
JBrowse link
G FGFR2 fibroblast growth factor receptor 2 IAGP DNA:mutations:exons,intron, splice site:varied mutations in different patients, mutations are somatic but identical germline mutations are associated with craniosynostosis and skeletal dysplasia syndromes
ClinVar Annotator: match by term: Endometrial Endometrioid Adenocarcinoma, Variant with Squamous Differentiation
ClinVar
RGD
PMID:7719344 PMID:8651276 PMID:9462761 PMID:9719378 PMID:10851026 More... RGD:2289862 NCBI chr10:121,478,330...121,598,458
Ensembl chr10:121,478,332...121,598,458
JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 disease_progression IEP RGD PMID:17952116 RGD:2301465 NCBI chr 7:45,912,245...45,921,272
Ensembl chr 7:45,912,245...45,921,874
JBrowse link
G INHA inhibin subunit alpha IEP protein:decreased expression:tumor:significantly higher in normal compared to malignant tissue RGD PMID:17143484 RGD:2290368 NCBI chr 2:219,572,310...219,575,711
Ensembl chr 2:219,569,162...219,575,711
JBrowse link
G INHBA inhibin subunit beta A IEP protein:decreased expression:endometrium RGD PMID:16423381 RGD:2301688 NCBI chr 7:41,685,114...41,705,406
Ensembl chr 7:41,667,168...41,705,834
JBrowse link
G KDR kinase insert domain receptor severity IEP protein:increased expression, increased phosphorylation:tumor:pKDR expression associated with poor overall survival (P=0.009) RGD PMID:16557278 RGD:2291929 NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595
JBrowse link
G KRAS KRAS proto-oncogene, GTPase IAGP associated with Ovarian Neoplasms RGD PMID:19542870 RGD:2314910 NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936
JBrowse link
G LNPEP leucyl and cystinyl aminopeptidase IEP associated with Endometrial Neoplasms RGD PMID:15218296 RGD:2314922 NCBI chr 5:96,936,080...97,037,513
Ensembl chr 5:96,935,394...97,037,513
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 treatment IDA RGD PMID:24917306 RGD:13441559 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 treatment IDA RGD PMID:24917306 RGD:13441559 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MSLN mesothelin EXP CTD Direct Evidence: marker/mechanism CTD PMID:14576474 NCBI chr16:760,734...768,865
Ensembl chr16:760,734...768,865
JBrowse link
G NKX2-1 NK2 homeobox 1 IDA DNA:hypermethylation RGD PMID:17504987 RGD:2290483 NCBI chr14:36,516,397...36,520,232
Ensembl chr14:36,516,392...36,521,149
JBrowse link
G PDGFRA platelet derived growth factor receptor alpha IEP protein:decreased expression:ovary RGD PMID:15791568 RGD:2298578 NCBI chr 4:54,229,293...54,298,245
Ensembl chr 4:54,229,280...54,298,245
JBrowse link
G PDGFRB platelet derived growth factor receptor beta IEP protein:increased expression:ovary RGD PMID:15791568 RGD:2298578 NCBI chr 5:150,113,839...150,155,845
Ensembl chr 5:150,113,839...150,155,872
JBrowse link
G PIK3R2 phosphoinositide-3-kinase regulatory subunit 2 IAGP ClinVar Annotator: match by term: Endometrial Endometrioid Adenocarcinoma, Variant with Squamous Differentiation ClinVar PMID:21984976 PMID:25741868 NCBI chr19:18,153,163...18,170,532
Ensembl chr19:18,153,163...18,170,532
JBrowse link
G POLE DNA polymerase epsilon, catalytic subunit ameliorates IAGP DNA:mutations:multiple (human) RGD PMID:29505428 RGD:151347648 NCBI chr12:132,623,762...132,687,342
Ensembl chr12:132,623,753...132,687,376
JBrowse link
G PTEN phosphatase and tensin homolog IAGP DNA:mutations: :multiple
DNA:loss of heterozygosity, mutations:multiple (human)
RGD PMID:17418409 PMID:11156411 RGD:2289817, RGD:12802357 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930
JBrowse link
G SPP1 secreted phosphoprotein 1 IDA RGD PMID:16633066 RGD:1581360 NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532
JBrowse link
G ST14 ST14 transmembrane serine protease matriptase IEP associated with Ovarian Neoplasms;protein:increased expression:ovary RGD PMID:16439987 RGD:2315091 NCBI chr11:130,159,782...130,210,362
Ensembl chr11:130,159,782...130,210,362
JBrowse link
G WIF1 WNT inhibitory factor 1 IEP mRNA:increased expression:ovary RGD PMID:16436637 RGD:2298535 NCBI chr12:65,050,626...65,121,305
Ensembl chr12:65,050,626...65,121,305
JBrowse link
endometriosis of uterus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BTK Bruton tyrosine kinase disease_progression ISO RGD PMID:31247078 RGD:124715471 NCBI chr  X:101,349,450...101,390,796
Ensembl chr  X:101,349,338...101,390,796
JBrowse link
G DNMT1 DNA methyltransferase 1 IEP protein:increased expression:ectopic endometrium: RGD PMID:22572543 RGD:9588664 NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286
JBrowse link
G DNMT3A DNA methyltransferase 3 alpha IEP protein:decreased expression:endometrium: RGD PMID:22572543 RGD:9588664 NCBI chr 2:25,227,874...25,342,590
Ensembl chr 2:25,227,855...25,342,590
JBrowse link
G DNMT3B DNA methyltransferase 3 beta IEP protein:increased expression:ectopic endometrium: RGD PMID:22572543 RGD:9588664 NCBI chr20:32,762,385...32,809,356
Ensembl chr20:32,762,385...32,809,359
JBrowse link
endometritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASP3 caspase 3 treatment ISO RGD PMID:26920733 RGD:13782281 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
JBrowse link
G CASP6 caspase 6 treatment ISO RGD PMID:26920733 RGD:13782281 NCBI chr 4:109,664,388...109,709,767
Ensembl chr 4:109,688,622...109,703,583
JBrowse link
G CASP7 caspase 7 treatment ISO RGD PMID:26920733 RGD:13782281 NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,730,907
JBrowse link
G CASP9 caspase 9 treatment ISO RGD PMID:26920733 RGD:13782281 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G IL1A interleukin 1 alpha ISO protein:increased expression:endometrium RGD PMID:25330821 RGD:11059518 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
JBrowse link
G TREM1 triggering receptor expressed on myeloid cells 1 ameliorates ISO RGD PMID:31365951 RGD:126928127 NCBI chr 6:41,267,385...41,286,682
Ensembl chr 6:41,267,926...41,286,682
JBrowse link
gestational trophoblastic neoplasm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C11orf80 chromosome 11 open reading frame 80 IEA OMIM:231090 MouseDO NCBI chr11:66,744,736...66,843,516
Ensembl chr11:66,744,451...66,843,516
JBrowse link
G KHDC3L KH domain containing 3 like, subcortical maternal complex member IEA OMIM:231090 MouseDO NCBI chr 6:73,362,658...73,364,171
Ensembl chr 6:73,362,658...73,364,171
JBrowse link
G MEI1 meiotic double-stranded break formation protein 1 IEA OMIM:231090 MouseDO NCBI chr22:41,699,503...41,799,454
Ensembl chr22:41,699,503...41,799,456
JBrowse link
G NLRP7 NLR family pyrin domain containing 7 IEA OMIM:231090 MouseDO NCBI chr19:54,923,509...54,947,505
Ensembl chr19:54,923,509...54,966,312
JBrowse link
G POU5F1 POU class 5 homeobox 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18440631 NCBI chr 6:31,164,337...31,170,682
Ensembl chr 6:31,164,337...31,180,731
JBrowse link
Hydatidiform Mole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CGA glycoprotein hormones, alpha polypeptide IEP protein:increased expression:serum RGD PMID:2473429 RGD:2293636 NCBI chr 6:87,085,498...87,095,106
Ensembl chr 6:87,085,498...87,095,106
JBrowse link
G KHDC3L KH domain containing 3 like, subcortical maternal complex member EXP
IAGP
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Hydatidiform mole
CTD
ClinVar
PMID:25741868 NCBI chr 6:73,362,658...73,364,171
Ensembl chr 6:73,362,658...73,364,171
JBrowse link
G MLH1 mutL homolog 1 IDA DNA, protein:hypermethylation, decreased expression:promoter, mononuclear cytotrophoblast cell RGD PMID:15338238 RGD:2293517 NCBI chr 3:36,993,466...37,050,846
Ensembl chr 3:36,993,350...37,050,846
JBrowse link
G MMP2 matrix metallopeptidase 2 IEP protein:increased expression:syncytiotrophoblast cell RGD PMID:16884384 RGD:2290363 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
JBrowse link
G MSH2 mutS homolog 2 IDA DNA, protein:hypermethylation, decreased expression:promoter, mononuclear cytotrophoblast cell RGD PMID:15338238 RGD:2293517 NCBI chr 2:47,403,067...47,634,501
Ensembl chr 2:47,403,067...47,663,146
JBrowse link
G NCR1 natural cytotoxicity triggering receptor 1 IAGP ClinVar Annotator: match by term: Hydatidiform mole ClinVar PMID:24033266 PMID:25741868 NCBI chr19:54,898,198...54,938,208
Ensembl chr19:54,906,148...54,916,140
JBrowse link
G NLRP7 NLR family pyrin domain containing 7 EXP
IAGP
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Hydatidiform mole
CTD
ClinVar
PMID:24033266 PMID:25741868 NCBI chr19:54,923,509...54,947,505
Ensembl chr19:54,923,509...54,966,312
JBrowse link
G PDGFRB platelet derived growth factor receptor beta IEP mRNA:increased expression:mononuclear cytotrophoblast cell RGD PMID:8504434 RGD:2292200 NCBI chr 5:150,113,839...150,155,845
Ensembl chr 5:150,113,839...150,155,872
JBrowse link
Hydatidiform Mole, Invasive term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MSH2 mutS homolog 2 IEP protein:decreased expression:mononuclear cytotrophoblast cell RGD PMID:15338238 RGD:2293517 NCBI chr 2:47,403,067...47,634,501
Ensembl chr 2:47,403,067...47,663,146
JBrowse link
Hydatidiform Mole, Recurrent, 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KIR3DL1 killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1 IAGP ClinVar Annotator: match by term: Hydatidiform mole, recurrent, 1 ClinVar PMID:19066229 PMID:21507883 PMID:24105752 NCBI chr19:54,816,438...54,830,778
Ensembl chr19:54,816,468...54,830,778
JBrowse link
G NCR1 natural cytotoxicity triggering receptor 1 IAGP ClinVar Annotator: match by term: Hydatidiform mole, recurrent, 1 ClinVar PMID:11598368 PMID:14756744 PMID:16239310 PMID:16462743 PMID:18039680 More... NCBI chr19:54,898,198...54,938,208
Ensembl chr19:54,906,148...54,916,140
JBrowse link
G NLRP7 NLR family pyrin domain containing 7 IAGP ClinVar Annotator: match by term: Hydatidiform mole, recurrent, 1 OMIM
ClinVar
PMID:2030859 PMID:10072436 PMID:10951527 PMID:11598368 PMID:12471053 More... NCBI chr19:54,923,509...54,947,505
Ensembl chr19:54,923,509...54,966,312
JBrowse link
Hydatidiform Mole, Recurrent, 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KHDC3L KH domain containing 3 like, subcortical maternal complex member IAGP ClinVar Annotator: match by term: Hydatidiform mole, recurrent, 2 ClinVar
OMIM
PMID:11932746 PMID:19246479 PMID:21623199 PMID:21885028 PMID:23125094 More... NCBI chr 6:73,362,658...73,364,171
Ensembl chr 6:73,362,658...73,364,171
JBrowse link
Hydatidiform Mole, Recurrent, 3 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MEI1 meiotic double-stranded break formation protein 1 IAGP ClinVar Annotator: match by term: HYDATIDIFORM MOLE, RECURRENT, 3 OMIM
ClinVar
PMID:25741868 PMID:30388401 NCBI chr22:41,699,503...41,799,454
Ensembl chr22:41,699,503...41,799,456
JBrowse link
Hydatidiform Mole, Recurrent, 4 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C11orf80 chromosome 11 open reading frame 80 IAGP ClinVar Annotator: match by term: HYDATIDIFORM MOLE, RECURRENT, 4 OMIM
ClinVar
PMID:25741868 PMID:30388401 NCBI chr11:66,744,736...66,843,516
Ensembl chr11:66,744,451...66,843,516
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 22089
    disease of anatomical entity 20653
      reproductive system disease 3536
        female reproductive system disease 2014
          uterine disease 521
            endometrial disease 298
              Endometrial Neoplasms + 287
              Metrorrhagia 0
              cervix endometrial stromal tumor + 0
              endometrial hyperplasia 16
              endometriosis of uterus 4
              endometritis + 6
              mixed endometrial stromal and smooth muscle tumor 0
              polyp of corpus uteri 0
              tamoxifen-related endometrial lesion 0
Path 2
Term Annotations click to browse term
  disease 22089
    disease of anatomical entity 20653
      Urogenital Diseases 5257
        Female Urogenital Diseases and Pregnancy Complications 2426
          Female Urogenital Diseases 2018
            female reproductive system disease 2014
              uterine disease 521
                endometrial disease 298
                  Endometrial Neoplasms + 287
                  Metrorrhagia 0
                  cervix endometrial stromal tumor + 0
                  endometrial hyperplasia 16
                  endometriosis of uterus 4
                  endometritis + 6
                  mixed endometrial stromal and smooth muscle tumor 0
                  polyp of corpus uteri 0
                  tamoxifen-related endometrial lesion 0
paths to the root