RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: preterm premature rupture of the membranes
Accession: DOID:0111144
browse the term
Definition: A female reproductive system disease characterized by rupture of chorioamniotic membranes before 37 weeks of gestation. (DO)
Synonyms: exact_synonym: PPROM; Preterm PROM (Pregnancy); Preterm Premature Rupture of Fetal Membranes
primary_id: MESH:C563032
alt_id: OMIM:610504 ; RDO:0012486
For additional species annotation, visit the
Alliance of Genome Resources .
G
F3
coagulation factor III, tissue factor
ISO
protein:increased expression:plasma
RGD
PMID:19012190
RGD:11340215
NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
G
Mmp1
matrix metallopeptidase 1
ISO
ClinVar Annotator: match by term: Preterm premature rupture of the membranes
ClinVar
PMID:9850057 PMID:11741975 PMID:11875051 PMID:18030675
NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
G
Mmp8
matrix metallopeptidase 8
ISO
ClinVar Annotator: match by term: Preterm premature rupture of the membranes
ClinVar
PMID:15367487
NCBI chr 8:4,724,009...4,732,956
Ensembl chr 8:4,724,029...4,733,520
G
Serpinh1
serpin family H member 1
susceptibility
ISO
CTD Direct Evidence: marker/mechanism ClinVar Annotator: match by term: Preterm premature rupture of the membranes
OMIM CTD ClinVar
PMID:16938879 PMID:25741868 PMID:28492532
NCBI chr 1:153,643,500...153,650,853
Ensembl chr 1:153,643,510...153,650,801
G
Tfpi
tissue factor pathway inhibitor
ISO
protein:decreased expression:plasma
RGD
PMID:19012190
RGD:11340215
NCBI chr 3:69,533,156...69,582,547
Ensembl chr 3:69,533,156...69,576,880
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