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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:latent autoimmune diabetes in adults
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Accession:DOID:0080846 term browser browse the term
Definition:A type 1 diabetes mellitus that is characterized by a less intensive autoimmune process, highly variable β-cell destruction, different degrees of insulin resistance and heterogeneous titre and pattern of islet autoantibody, sharing features with both type 1 and type 2 diabetes mellitus. (DO)
Synonyms:exact_synonym: Diabetes Mellitus Type 1.5;   LADA;   LADA, Latent Autoimmune Diabetes in Adults;   Latent Autoimmune Diabetes of Adults;   type 1.5 diabetes
 primary_id: MESH:D000071698
 xref: EFO:0009706



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latent autoimmune diabetes in adults term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 ISO DNA:SNP: :49A>G (human) RGD PMID:12021137 RGD:2301997 NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963
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G LOC120095693 small ubiquitin-related modifier 2-like ISO ClinVar Annotator: match by term: Type 1 diabetes mellitus 5 ClinVar PMID:15123604 PMID:15247916 PMID:15678134 PMID:15678135 PMID:15678137 NCBI chr11:79,163,457...79,164,088
Ensembl chr11:79,163,634...79,163,960
JBrowse link
G Tab2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 ISO ClinVar Annotator: match by term: Type 1 diabetes mellitus 5 ClinVar PMID:15123604 PMID:15247916 PMID:15678134 PMID:15678135 PMID:15678137 NCBI chr 1:2,375,026...2,425,115
Ensembl chr 1:2,375,490...2,424,756
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 21128
    disease of anatomical entity 18211
      endocrine system disease 6775
        diabetes mellitus 1660
          type 1 diabetes mellitus 383
            latent autoimmune diabetes in adults 3
Path 2
Term Annotations click to browse term
  disease 21128
    Developmental Disease 18449
      Congenital, Hereditary, and Neonatal Diseases and Abnormalities 18309
        genetic disease 18253
          inherited metabolic disorder 6214
            carbohydrate metabolic disorder 3267
              glucose metabolism disease 2071
                diabetes mellitus 1660
                  type 1 diabetes mellitus 383
                    latent autoimmune diabetes in adults 3
paths to the root