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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:acute asthma
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Accession:DOID:0080810 term browser browse the term
Definition:An asthma that is characterized by severe and sudden onset of increasing wheezing, airways closing, smooth muscle contraction, mucus plugging and lower airway edema that may be reversible upon treatment. (DO)


show annotations for term's descendants           Sort by:
status asthmaticus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma resistance ISO RGD PMID:20817868 RGD:4145651 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il1b interleukin 1 beta ISO protein:increased expression:lung RGD PMID:9927362 RGD:4143184 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il5 interleukin 5 ISO protein:increased expression:respiratory system fluid/secretion RGD PMID:10934091 RGD:4890960 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213 		JBrowse link
G Mpo myeloperoxidase ISO protein:increased expression:serum RGD PMID:10731862 RGD:5130994 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19099
    disease of anatomical entity 18440
      respiratory system disease 5241
        respiratory allergy 393
          asthma 354
            acute asthma 4
              near-fatal asthma 0
              status asthmaticus 4
Path 2
Term Annotations click to browse term
  disease 19099
    disease of anatomical entity 18440
      Immune & Inflammatory Diseases 5757
        immune system disease 5027
          allergic disease 618
            Immediate Hypersensitivity 469
              respiratory allergy 393
                asthma 354
                  acute asthma 4
                    near-fatal asthma 0
                    status asthmaticus 4
paths to the root