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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:nasal type extranodal NK/T-cell lymphoma
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Accession:DOID:0080797 term browser browse the term
Definition:A mature T-cell and NK-cell lymphoma that is characterized by an often angiocentric and angiodestructive cellular infiltrate composed of EBV positive NK/T cells. (DO)
Synonyms:exact_synonym: Extranodal NK T Cell Lymphoma, Nasal;   Extranodal NK T Cell Lymphoma, Nasal and Nasal Type;   Extranodal NK-T-Cell Lymphomas;   extranodal NK-T-cell lymphoma
 primary_id: MESH:D054391
 xref: MONDO:0019472;   NCI:C4684


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nasal type extranodal NK/T-cell lymphoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 severity IEP Nasal Type;protein:increased expression:nasal cavity (human) RGD PMID:18756548 RGD:8657087 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G CD274 CD274 molecule disease_progression IEP associated with Epstein-Barr Virus Infections RGD PMID:27595782 RGD:41412182 NCBI chr 9:5,450,542...5,470,554
Ensembl chr 9:5,450,503...5,470,566 		JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator EXP CTD Direct Evidence: marker/mechanism CTD PMID:15924153 NCBI chr 2:201,116,164...201,176,687
Ensembl chr 2:201,116,154...201,176,687 		JBrowse link
G FAS Fas cell surface death receptor IAGP DNA:insertion, deletions:cds:multiple (human) RGD PMID:12466128 RGD:8662407 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G GPX3 glutathione peroxidase 3 treatment IEP associated with ethmoid sinus cancer and Neoplasm Metastasis RGD PMID:29496492 RGD:151708712 NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988 		JBrowse link
G JAK3 Janus kinase 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22705984 PMID:23689514 NCBI chr19:17,824,782...17,847,982
Ensembl chr19:17,824,780...17,848,071 		JBrowse link
G PRDM1 PR/SET domain 1 disease_progression IEP RGD PMID:24438193 RGD:150530467 NCBI chr 6:105,992,690...106,109,938
Ensembl chr 6:105,993,463...106,109,939 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 IEP protein:increased expression:nasal cavity (human) RGD PMID:17225522 RGD:153298933 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
G STAT5B signal transducer and activator of transcription 5B EXP CTD Direct Evidence: marker/mechanism CTD PMID:29200404 NCBI chr17:42,199,177...42,288,370
Ensembl chr17:42,199,176...42,288,633 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 41189
    disease of cellular proliferation 9736
      Neoplasms by Histologic Type 6406
        lymphoma 573
          non-Hodgkin lymphoma 484
            T-cell non-Hodgkin lymphoma 169
              nasal type extranodal NK/T-cell lymphoma 9
Path 2
Term Annotations click to browse term
  disease 41189
    disease of anatomical entity 32344
      nervous system disease 26233
        Neurologic Manifestations 15387
          sensory system disease 9730
            Otorhinolaryngologic Diseases 2281
              nose disease 236
                paranasal sinus disease 62
                  Paranasal Sinus Neoplasms 18
                    Sinonasal Neoplasms 15
                      nasal cavity cancer 15
                        nasal type extranodal NK/T-cell lymphoma 9
paths to the root