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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:meningococcal meningitis
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Accession:DOID:0080176 term browser browse the term
Definition:A bacterial meningitis that has_material_basis_in Neisseria meningitidis infection. (DO)
Synonyms:exact_synonym: meningococcic meningitis
 narrow_synonym: meningococcal meningitis, serogroup C;   meningococcal meningitis, serogroup A;   meningococcal meningitis, serogroup B;   meningococcal meningitis, serogroup W 135;   meningococcal meningitis, serogroup W135;   meningococcal meningitis, serogroup Y
 primary_id: MESH:D008585
 xref: EFO:1001040;   ICD10CM:A39.0;   ICD9CM:036.0


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meningococcal meningitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C9 complement C9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9570574 NCBI chr16:24,521,318...24,575,939
Ensembl chr16:24,520,634...24,590,338 		JBrowse link
G CD46 CD46 molecule, complement regulatory protein ISO RGD PMID:12869763 RGD:6483466 NCBI chr 9:135,025,439...135,078,910 JBrowse link
G CFP complement factor properdin ISO CTD Direct Evidence: marker/mechanism CTD PMID:8530058 PMID:10909851 NCBI chr  X:42,145,754...42,152,879
Ensembl chr  X:42,143,697...42,152,868 		JBrowse link
G MARCO macrophage receptor with collagenous structure ISO protein:increased expression:sub-cortical, meninges, astrocyte RGD PMID:21299846 RGD:41412190 NCBI chr15:24,502,935...24,541,286
Ensembl chr15:24,503,108...24,541,283 		JBrowse link
G MMP13 matrix metallopeptidase 13 ISO RGD PMID:10430840 RGD:8547971 NCBI chr 9:33,549,003...33,616,700
Ensembl chr 9:33,549,008...33,561,162 		JBrowse link
G MMP9 matrix metallopeptidase 9 ISO RGD PMID:10430840 RGD:8547971 NCBI chr17:48,179,690...48,186,782
Ensembl chr17:48,179,671...48,186,788 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 susceptibility ISO DNA:SNP,haplotype: :SNP8(human) RGD PMID:23691182 RGD:7800668 NCBI chr 6:34,132,127...34,167,446
Ensembl chr 6:34,130,938...34,177,534 		JBrowse link
G SLC11A1 solute carrier family 11 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16597321 NCBI chr15:120,434,100...120,446,396
Ensembl chr15:120,433,952...120,446,396 		JBrowse link
G TLR2 toll like receptor 2 susceptibility ISO DNA:haplotype: :2477G>A(rs5743708)(human) RGD PMID:23691182 RGD:7800668 NCBI chr 8:75,416,257...75,428,370
Ensembl chr 8:75,411,993...75,428,330 		JBrowse link
G TLR4 toll like receptor 4 susceptibility ISO DNA:SNP,haplotype: :896A>G(rs4986790)(human) RGD PMID:23691182 RGD:7800668 NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,058,970 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17412
    disease by infectious agent 2089
      Bacterial Infections and Mycoses 997
        Central Nervous System Infections 266
          Central Nervous System Bacterial Infections 45
            bacterial meningitis 38
              meningococcal meningitis 10
                Waterhouse-Friderichsen syndrome + 0
Path 2
Term Annotations click to browse term
  disease 17412
    disease by infectious agent 2089
      Bacterial Infections and Mycoses 997
        bacterial infectious disease 791
          Gram-Negative Bacterial Infections 192
            Neisseriaceae Infections 21
              Meningococcal Infections 18
                meningococcal meningitis 10
                  Waterhouse-Friderichsen syndrome + 0
paths to the root