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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:thrombosis
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Accession:DOID:0060903 term browser browse the term
Definition:A vascular disease caused by the formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system. (DO)
Synonyms:exact_synonym: Blood Clot;   Blood Clots;   Thromboses;   Thrombus
 primary_id: MESH:D013927


show annotations for term's descendants           Sort by:
thrombosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace2 angiotensin converting enzyme 2 treatment IDA RGD PMID:20111697 RGD:9685451 NCBI chr  X:30,293,597...30,340,961 JBrowse link
G Adamts13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 ISO ClinVar Annotator: match by term: Thrombus ClinVar PMID:25741868 PMID:28492532 NCBI chr 3:10,299,264...10,338,464 JBrowse link
G Agt angiotensinogen ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:11881036 PMID:21501650 NCBI chr19:69,426,540...69,447,017 JBrowse link
G Apoh apolipoprotein H IDA RGD PMID:24642748 RGD:10054118 NCBI chr10:93,342,435...93,356,334 JBrowse link
G Bdkrb2 bradykinin receptor B2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16514058 NCBI chr 6:130,237,055...130,267,205 JBrowse link
G C5ar1 complement C5a receptor 1 IMP associated with Anti-Glomerular Basement Membrane Disease RGD PMID:11422211 RGD:1600652 NCBI chr 1:76,948,622...76,959,826 JBrowse link
G Cd2 Cd2 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:16932337 NCBI chr 2:188,710,895...188,724,044 JBrowse link
G Cd40 CD40 molecule ISO RGD PMID:21914625 RGD:5490522 NCBI chr 3:174,209,113...174,224,592 JBrowse link
G Cd40lg CD40 ligand susceptibility
treatment		 ISO
IDA		 associated with Endotoxemia
protein:increased expression:plasma (human)		 RGD PMID:21914625 PMID:15306157 PMID:27085896 RGD:5490522, RGD:11352250, RGD:11344959 NCBI chr  X:140,164,341...140,176,057 JBrowse link
G Crp C-reactive protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:16931792 NCBI chr13:87,694,062...87,695,978 JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20978260 NCBI chr 1:247,879,058...247,916,804 JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16754899 NCBI chr12:21,919,955...21,960,160 JBrowse link
G Epo erythropoietin ISO CTD Direct Evidence: marker/mechanism CTD PMID:14979412 PMID:25013951 NCBI chr12:19,204,258...19,207,948 JBrowse link
G F10 coagulation factor X ISO CTD Direct Evidence: marker/mechanism CTD PMID:1279834 NCBI chr16:83,170,973...83,190,280 JBrowse link
G F11 coagulation factor XI susceptibility ISO DNA:SNPs:intron: rs2289252,rs2036914(human) RGD PMID:22633531 PMID:19583818 RGD:11041774, RGD:11041778 NCBI chr16:46,987,988...47,009,015 JBrowse link
G F12 coagulation factor XII ISO ClinVar Annotator: match by term: Thrombus ClinVar PMID:25741868 NCBI chr17:9,212,819...9,220,664 JBrowse link
G F13b coagulation factor XIII B chain ISO ClinVar Annotator: match by term: Thrombus ClinVar PMID:25741868 NCBI chr13:51,130,908...51,156,383 JBrowse link
G F2 coagulation factor II, thrombin treatment
no_association		 ISO
IEP
IDA		 DNA:mutation: :20210G>A (human)
CTD Direct Evidence: marker/mechanism
associated with Carotid Artery Injuries
associated with Behcet Syndrome;DNA:mutation: :20210G>A (human)		 CTD
RGD		 PMID:1279834 PMID:10064001 PMID:11132655 PMID:17245631 PMID:21070754 More... RGD:6893603, RGD:11035267, RGD:10449423, RGD:7394765, RGD:7387314, RGD:7387259 NCBI chr 3:98,051,958...98,065,246 JBrowse link
G F2r coagulation factor II (thrombin) receptor ISO RGD PMID:14529396 RGD:1581036 NCBI chr 2:26,869,343...26,885,856 JBrowse link
G F3 coagulation factor III, tissue factor ISO associated with Antiphospholipid Syndrome
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:11858183 PMID:25339356 PMID:9153543 RGD:11340222 NCBI chr 2:212,511,675...212,523,375 JBrowse link
G F5 coagulation factor V ISO associated with kidney failure, chronic;DNA:mutation: :1691G>A(human)
ClinVar Annotator: match by term: Thrombus
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
RGD		 PMID:9164807 PMID:11132655 PMID:25741868 PMID:16549134 PMID:11110695 RGD:6893627, RGD:11564340 NCBI chr13:79,046,657...79,116,247 JBrowse link
G F9 coagulation factor IX ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Thrombus		 CTD
ClinVar		 PMID:1279834 PMID:7937052 PMID:19846852 PMID:25741868 NCBI chr  X:143,388,642...143,433,143 JBrowse link
G Fcgr2a Fc gamma receptor 2A no_association ISO associated with Thrombocytopenia;DNA:polymorphism: :p.H131R (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:11588041 PMID:9002937 PMID:18983497 PMID:20585032 RGD:5147983, RGD:11040996, RGD:5147987 NCBI chr13:85,813,516...85,830,269 JBrowse link
G Fga fibrinogen alpha chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:8473507 NCBI chr 2:170,672,169...170,679,572 JBrowse link
G Fgb fibrinogen beta chain susceptibility ISO associated with Lupus Nephritis;;DNA:polymorphism: :-455G>A (human)
ClinVar Annotator: match by term: Thrombus		 ClinVar
RGD		 PMID:10688828 PMID:19420351 PMID:20978265 PMID:24033266 PMID:25741868 More... RGD:7175506 NCBI chr 2:168,394,901...168,402,863 JBrowse link
G Fgg fibrinogen gamma chain ISO ClinVar Annotator: match by term: Thrombus ClinVar PMID:10688828 PMID:15795540 PMID:17938819 PMID:19300242 PMID:21228398 More... NCBI chr 2:168,354,880...168,362,325 JBrowse link
G Flt3 Fms related receptor tyrosine kinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16932337 NCBI chr12:12,660,035...12,735,584 JBrowse link
G Fut4 fucosyltransferase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16932337 NCBI chr 8:11,586,721...11,590,682 JBrowse link
G Gas6 growth arrest specific 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11175853 PMID:15130911 PMID:15733062 PMID:16564713 NCBI chr16:82,747,676...82,778,090 JBrowse link
G Gp1ba glycoprotein Ib platelet subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:17334511 NCBI chr10:55,352,938...55,355,804 JBrowse link
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24213632 NCBI chr 2:167,418,615...167,482,293 JBrowse link
G Hgf hepatocyte growth factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:15367830 NCBI chr 4:19,628,902...19,700,467 JBrowse link
G Hmox1 heme oxygenase 1 ISO CTD Direct Evidence: therapeutic CTD
RGD		 PMID:19168058 PMID:15242554 RGD:1598405 NCBI chr19:13,452,365...13,479,823 JBrowse link
G Hrg histidine-rich glycoprotein ISO DNA, protein:missense mutation, decreased expression:exon, plasma:p.G85E (429G>A) (human)
ClinVar Annotator: match by term: Thrombus		 ClinVar
RGD		 PMID:25741868 PMID:34355501 PMID:9414276 RGD:1599656 NCBI chr11:78,054,488...78,069,402 JBrowse link
G Il10 interleukin 10 ISO RGD PMID:12765335 RGD:1598469 NCBI chr13:45,024,921...45,029,586 JBrowse link
G Itga2 integrin subunit alpha 2 susceptibility ISO associated with Behcet Syndrome;DNA:snp:cds:c.807C>T (human) RGD PMID:14563646 PMID:12412731 RGD:1582298, RGD:1582300 NCBI chr 2:46,520,345...46,621,487 JBrowse link
G Itgam integrin subunit alpha M ISO associated with atrial fibrillation;protein:increased expression:monocyte, granulocyte (human) RGD PMID:26411420 RGD:329901838 NCBI chr 1:192,089,496...192,139,947 JBrowse link
G Jak2 Janus kinase 2 IAGP associated with Budd-Chiari syndrome;DNA:missense mutation:cds:p.V617F (human) RGD PMID:22467227 RGD:15039391 NCBI chr 1:236,408,905...236,468,769 JBrowse link
G Klf4 KLF transcription factor 4 ISO CTD Direct Evidence: therapeutic CTD PMID:25339356 NCBI chr 5:75,074,107...75,079,182 JBrowse link
G Klkb1 kallikrein B1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25339356 NCBI chr16:46,958,634...46,982,054 JBrowse link
G Kng1 kininogen 1 ISO ClinVar Annotator: match by term: Thrombus ClinVar PMID:25741868 NCBI chr11:77,812,757...77,835,555 JBrowse link
G Lrp8 LDL receptor related protein 8 ISO associated with Antiphospholipid Syndrome RGD PMID:21119114 RGD:6483062 NCBI chr 5:127,792,236...127,864,207 JBrowse link
G Mas1 MAS1 proto-oncogene, G protein-coupled receptor ISO CTD Direct Evidence: therapeutic CTD PMID:25339356 NCBI chr 1:50,428,064...50,459,537 JBrowse link
G Mertk MER proto-oncogene, tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:15130911 PMID:15130911 RGD:1582496 NCBI chr 3:136,391,936...136,498,366 JBrowse link
G Mmp1 matrix metallopeptidase 1 ISO associated with Arteriovenous Fistula;DNA:insertion:promoter:g.-1607insG (rs11292517) (human) RGD PMID:20616161 RGD:7207048 NCBI chr 8:12,943,453...12,963,966 JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO associated with Arteriovenous Fistula;DNA:insertion:promoter:g.-1612insA (rs35068180) (human) RGD PMID:20616161 RGD:7207048 NCBI chr 8:12,925,267...12,938,828 JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO associated with Arteriovenous Fistula;DNA:snp:promoter:g.-1562C>A (rs34016235) (human) RGD PMID:20616161 RGD:7207048 NCBI chr 3:174,103,474...174,111,434 JBrowse link
G Mthfr methylenetetrahydrofolate reductase no_association ISO DNA:SNP: :677C>T (human) RGD PMID:10780318 RGD:10449414 NCBI chr 5:163,748,346...163,768,141 JBrowse link
G P2ry1 purinergic receptor P2Y1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17334511 NCBI chr 2:145,241,975...145,248,186 JBrowse link
G P2ry12 purinergic receptor P2Y12 ISO
IMP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:17334511 PMID:12897207 PMID:19692114 RGD:1580187, RGD:6480647 NCBI chr 2:143,481,468...143,523,340 JBrowse link
G Pde3a phosphodiesterase 3A ISO CTD Direct Evidence: marker/mechanism CTD PMID:17482796 NCBI chr 4:174,172,804...174,443,944 JBrowse link
G Pf4 platelet factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8282825 PMID:9446652 PMID:11588041 PMID:15795722 NCBI chr14:17,582,477...17,583,392 JBrowse link
G Pi4ka phosphatidylinositol 4-kinase alpha ISO ClinVar Annotator: match by term: Thrombus ClinVar PMID:25741868 NCBI chr11:97,113,390...97,234,374 JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta IMP RGD PMID:15834429 RGD:1580861 NCBI chr 8:108,474,017...108,579,140 JBrowse link
G Plat plasminogen activator, tissue type ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:2123154 PMID:12677255 PMID:19348381 PMID:22352330 NCBI chr16:75,943,061...76,022,037 JBrowse link
G Plau plasminogen activator, urokinase IEP
ISO		 protein:increased activity:extracellular region (rat)
CTD Direct Evidence: therapeutic		 CTD
RGD		 PMID:2106299 PMID:2133253 PMID:2795766 PMID:4884574 PMID:8657906 More... RGD:2325698 NCBI chr15:3,505,485...3,511,987 JBrowse link
G Plg plasminogen ISO ClinVar Annotator: match by term: Thrombus ClinVar PMID:25741868 PMID:28492532 PMID:34355501 NCBI chr 1:48,325,186...48,367,643 JBrowse link
G Podxl podocalyxin-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:22016802 NCBI chr 4:60,135,124...60,181,829 JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:8967151 PMID:9164807 PMID:11132655 PMID:18376272 PMID:8073406 RGD:11250413 NCBI chr18:24,038,596...24,049,061 JBrowse link
G Pros1 protein S ISO CTD Direct Evidence: marker/mechanism CTD PMID:10706858 PMID:11132655 NCBI chr11:13,676,310...13,757,858 JBrowse link
G Ptger3 prostaglandin E receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17242161 NCBI chr 2:246,606,131...246,750,970 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20350286 NCBI chr13:64,714,063...64,722,320 JBrowse link
G Selp selectin P ISO CTD Direct Evidence: marker/mechanism CTD PMID:10544909 NCBI chr13:76,476,229...76,511,846 JBrowse link
G Serpinc1 serpin family C member 1 treatment ISO
IDA		 DNA:missense mutation:cds:p.F229L (human)
CTD Direct Evidence: marker/mechanism|therapeutic		 CTD
RGD		 PMID:2133253 PMID:6889048 PMID:8967151 PMID:11132655 PMID:12595305 More... RGD:1580119, RGD:11035267 NCBI chr13:75,790,558...75,804,826 JBrowse link
G Serpind1 serpin family D member 1 ISO ClinVar Annotator: match by term: Thrombus ClinVar PMID:25741868 NCBI chr11:83,664,517...83,675,593 JBrowse link
G Serpine1 serpin family E member 1 susceptibility
no_association		 ISO associated with Lupus Nephritis;;DNA:insertion/deletion: :
ClinVar Annotator: match by term: Thrombus
CTD Direct Evidence: marker/mechanism
associated with Behcet Syndrome;DNA:deletion:promoter:g.-676_-674delG (human)
associated with Behcet Syndrome;protein:increased expression:plasma (human)		 ClinVar
CTD
RGD		 PMID:12677255 PMID:22352330 PMID:25741868 PMID:17469143 PMID:12632020 More... RGD:7175506, RGD:7394765, RGD:8547802 NCBI chr12:25,237,977...25,248,356 JBrowse link
G Sirt1 sirtuin 1 ISO CTD Direct Evidence: therapeutic CTD PMID:25339356 NCBI chr20:25,305,953...25,328,000 JBrowse link
G Spta1 spectrin, alpha, erythrocytic 1 ISO RGD PMID:9845553 RGD:11059524 NCBI chr13:86,203,504...86,279,371 JBrowse link
G Tbxas1 thromboxane A synthase 1 IDA RGD PMID:12384182 RGD:1601457 NCBI chr 4:67,664,963...67,837,096 JBrowse link
G Thbd thrombomodulin ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Thrombus		 CTD
ClinVar		 PMID:11132655 PMID:11518727 PMID:25741868 NCBI chr 3:156,316,526...156,320,178 JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19691487 NCBI chr20:3,626,685...3,629,303 JBrowse link
G Tyro3 TYRO3 protein tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:15733062 PMID:15733062 RGD:1580531 NCBI chr 3:127,231,468...127,254,806 JBrowse link
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Thrombus		 CTD
ClinVar		 PMID:15883587 PMID:15888487 PMID:15930419 PMID:15947090 PMID:16580898 More... NCBI chr 1:191,932,969...191,935,490 JBrowse link
G Vtn vitronectin ISO RGD PMID:15069014 RGD:1580815 NCBI chr10:63,394,732...63,397,812 JBrowse link
G Vwf von Willebrand factor ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Thrombus		 CTD
ClinVar		 PMID:3875694 PMID:12649144 PMID:14525793 PMID:15755288 PMID:15842375 More... NCBI chr 4:160,042,900...160,177,757 JBrowse link
Arterial Thrombosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F7 coagulation factor VII treatment IMP
ISO		 human protein in a rat model RGD PMID:12714830 PMID:11167855 RGD:11041657, RGD:11049507 NCBI chr16:83,191,896...83,202,775 JBrowse link
G Flna filamin A ISO ClinVar Annotator: match by term: Arterial thrombosis ClinVar PMID:25741868 NCBI chr  X:157,159,051...157,185,559 JBrowse link
G Gp6 glycoprotein VI ameliorates
treatment		 ISO
IMP		 RGD PMID:25051961 PMID:17322098 PMID:16254207 PMID:23448972 PMID:15507524 RGD:401794404, RGD:401824682, RGD:401824681, RGD:401824648, RGD:401824646 NCBI chr 1:78,471,900...78,535,374 JBrowse link
G Gsn gelsolin ameliorates ISO human gene in mouse model RGD PMID:31002695 RGD:329333020 NCBI chr 3:38,982,605...39,035,849 JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha IEP protein:increased expression:plantar, foot muscle (rat) RGD PMID:22351094 RGD:8695963 NCBI chr 6:98,357,788...98,405,068 JBrowse link
G Il17a interleukin 17A ISO mouse protein in a rat model RGD PMID:24940514 RGD:9068933 NCBI chr 9:30,640,844...30,644,331 JBrowse link
G Mbl2 mannose binding lectin 2 treatment ISO RGD PMID:25482922 RGD:11530049 NCBI chr 1:237,429,873...237,465,567 JBrowse link
G Plat plasminogen activator, tissue type treatment ISO associated with Antiphospholipid Syndrome RGD PMID:14630788 PMID:24806322 RGD:11541057, RGD:11541078 NCBI chr16:75,943,061...76,022,037 JBrowse link
G Serpine1 serpin family E member 1 IEP protein:increased expression:plasma (rat) RGD PMID:26857113 RGD:11073687 NCBI chr12:25,237,977...25,248,356 JBrowse link
G Serpinf1 serpin family F member 1 treatment ISO human protein in a rat model RGD PMID:17850801 RGD:8655540 NCBI chr10:60,250,198...60,262,593 JBrowse link
G Xdh xanthine dehydrogenase treatment IMP RGD PMID:26374946 RGD:13208952 NCBI chr 6:21,530,463...21,592,172 JBrowse link
Budd-Chiari syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa1 apolipoprotein A1 ISO protein: decreased expression: plasma (human) RGD PMID:21145806 RGD:25671435 NCBI chr 8:55,423,945...55,425,729 JBrowse link
G F5 coagulation factor V severity
disease_progression
susceptibility		 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Budd-Chiari syndrome
DNA:missense mutation:cds:R506Q (human)
associated with hyperhomocysteinemia:DNA:missense mutation:cds: (R506Q) (human)		 OMIM
CTD
ClinVar
RGD		 PMID:11950065 PMID:16246256 PMID:19486170 PMID:24033266 PMID:25741868 More... RGD:14700660, RGD:11537993, RGD:15036813, RGD:14700661 NCBI chr13:79,046,657...79,116,247 JBrowse link
G Insl6 insulin-like 6 ISO ClinVar Annotator: match by term: Budd-Chiari syndrome ClinVar PMID:15781101 PMID:15793561 PMID:15837627 PMID:15858187 PMID:15920007 More... NCBI chr 1:227,069,958...227,073,493 JBrowse link
G Jak2 Janus kinase 2 ISO ClinVar Annotator: match by term: Budd-Chiari syndrome
CTD Direct Evidence: marker/mechanism		 OMIM
ClinVar
CTD		 PMID:15781101 PMID:15793561 PMID:15837627 PMID:15858187 PMID:15920007 More... NCBI chr 1:236,408,905...236,468,769 JBrowse link
G Mthfr methylenetetrahydrofolate reductase susceptibility ISO DNA:transition: :677C>T (human)
DNA:SNPs: :DNA:SNPs: :677C>T, 1298A>C(human)		 RGD PMID:12221667 PMID:26238013 RGD:10449395, RGD:11537993 NCBI chr 5:163,748,346...163,768,141 JBrowse link
carotid artery thrombosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F3 coagulation factor III, tissue factor ISO associated with Diabetes Mellitus, Non-Insulin-Dependent RGD PMID:17969370 RGD:2313859 NCBI chr 2:212,511,675...212,523,375 JBrowse link
G Gp1bb glycoprotein Ib platelet subunit beta ISO RGD PMID:17095718 RGD:11040529 NCBI chr11:82,378,216...82,379,393 JBrowse link
G Hmox1 heme oxygenase 1 treatment ISO associated with Anemia, Sickle Cell RGD PMID:23590132 RGD:10755698 NCBI chr19:13,452,365...13,479,823 JBrowse link
G Itga2b integrin subunit alpha 2b ISO CTD Direct Evidence: marker/mechanism CTD PMID:1605806 NCBI chr10:87,408,532...87,426,055 JBrowse link
G Itgb3 integrin subunit beta 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:1605806 NCBI chr10:90,009,927...90,067,787 JBrowse link
G Klkb1 kallikrein B1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25339356 NCBI chr16:46,958,634...46,982,054 JBrowse link
G Serpind1 serpin family D member 1 ISO CTD Direct Evidence: therapeutic CTD PMID:11805133 NCBI chr11:83,664,517...83,675,593 JBrowse link
G Stxbp2 syntaxin binding protein 2 ISO CTD Direct Evidence: therapeutic CTD PMID:30696774 NCBI chr12:6,487,265...6,498,351 JBrowse link
G Thbd thrombomodulin ISO RGD PMID:21885846 RGD:5684980 NCBI chr 3:156,316,526...156,320,178 JBrowse link
G Tlr2 toll-like receptor 2 ISO RGD PMID:28572286 RGD:15090824 NCBI chr 2:171,499,189...171,504,831 JBrowse link
central retinal vein occlusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Proc protein C, inactivator of coagulation factors Va and VIIIa treatment ISO RGD PMID:20688738 RGD:11100028 NCBI chr18:24,038,596...24,049,061 JBrowse link
G Serpinf1 serpin family F member 1 IEP protein:increased expression:neuroretina (rat) RGD PMID:21487926 RGD:5490120 NCBI chr10:60,250,198...60,262,593 JBrowse link
cerebral venous thrombosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1a calcium voltage-gated channel subunit alpha1 A ISO ClinVar Annotator: match by term: Cerebral venous thrombosis ClinVar PMID:25741868 PMID:26467025 PMID:28492532 NCBI chr19:40,425,560...40,724,810 JBrowse link
G Gpx3 glutathione peroxidase 3 no_association ISO DNA:SNPs, haplotype:promoter:-942 A>C, -927 T>C, -861 A>T, -302 A>T, -284 T>A, -568 T>C, -518 T>C, -65 T>C (human) RGD PMID:18096833 PMID:19095977 RGD:401827161, RGD:401827164 NCBI chr10:39,529,335...39,537,406 JBrowse link
coronary thrombosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gp6 glycoprotein VI ISO DNA:missense mutation:CDS:c.13254T>C (human) RGD PMID:15306180 RGD:401793750 NCBI chr 1:78,471,900...78,535,374 JBrowse link
G Itgb3 integrin subunit beta 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8598867 NCBI chr10:90,009,927...90,067,787 JBrowse link
G Plat plasminogen activator, tissue type ISO CTD Direct Evidence: therapeutic CTD PMID:1452937 PMID:8172379 PMID:15301905 NCBI chr16:75,943,061...76,022,037 JBrowse link
heparin cofactor II deficiency term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pi4ka phosphatidylinositol 4-kinase alpha ISO ClinVar Annotator: match by term: Heparin cofactor II deficiency | ClinVar Annotator: match by term: SERPIND1-related condition | ClinVar Annotator: match by term: Thrombotic stroke ClinVar PMID:2647747 PMID:8562924 PMID:8902986 PMID:11204559 PMID:25741868 More... NCBI chr11:97,113,390...97,234,374 JBrowse link
G Serpind1 serpin family D member 1 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Heparin cofactor II deficiency | ClinVar Annotator: match by term: SERPIND1-related condition | ClinVar Annotator: match by term: Thrombotic stroke		 OMIM
CTD
ClinVar		 PMID:2647747 PMID:8562924 PMID:8902986 PMID:11204559 PMID:25741868 More... NCBI chr11:83,664,517...83,675,593 JBrowse link
intracranial sinus thrombosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2 coagulation factor II, thrombin ISO CTD Direct Evidence: marker/mechanism CTD PMID:12269725 NCBI chr 3:98,051,958...98,065,246 JBrowse link
G Gpx3 glutathione peroxidase 3 no_association ISO DNA:SNPs, haplotypes:promoter:rs8177412, rs870407, rs870406 (human) RGD PMID:20946167 RGD:401827165 NCBI chr10:39,529,335...39,537,406 JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:18941937 NCBI chr 5:163,748,346...163,768,141 JBrowse link
intracranial thrombosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plat plasminogen activator, tissue type ISO CTD Direct Evidence: therapeutic CTD PMID:8678742 NCBI chr16:75,943,061...76,022,037 JBrowse link
G Serpinc1 serpin family C member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:6636041 NCBI chr13:75,790,558...75,804,826 JBrowse link
G Vwf von Willebrand factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:3111251 NCBI chr 4:160,042,900...160,177,757 JBrowse link
Lower Extremity Deep Vein Thrombosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 ISO associated with Behcet Syndrome;protein:increased expression:serum (human) RGD PMID:16273763 RGD:8548850 NCBI chr10:67,503,077...67,504,875 JBrowse link
portal vein thrombosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2 coagulation factor II, thrombin severity ISO associated with liver cirrhosis;protein:increased expression:plasma (human) RGD PMID:28465646 RGD:14985237 NCBI chr 3:98,051,958...98,065,246 JBrowse link
G Igf1r insulin-like growth factor 1 receptor susceptibility ISO associated with hepatocellular carcinoma;DNA:SNP:3'UTR:rs3743251(human) RGD PMID:24758241 RGD:14985227 NCBI chr 1:130,959,787...131,248,664 JBrowse link
G Mthfr methylenetetrahydrofolate reductase susceptibility ISO DNA:SNP: :677C>T(human) RGD PMID:27221722 PMID:25987440 RGD:14696705, RGD:14696749 NCBI chr 5:163,748,346...163,768,141 JBrowse link
G Serpine1 serpin family E member 1 susceptibility ISO DNA:polymorphism:promoter: RGD PMID:25987440 RGD:14696749 NCBI chr12:25,237,977...25,248,356 JBrowse link
retinal vein occlusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 IEP RGD PMID:21487926 RGD:5490120 NCBI chr 4:85,812,784...85,824,964 JBrowse link
G Aqp4 aquaporin 4 IEP mRNA:decreased expression:retina RGD PMID:21487926 RGD:5490120 NCBI chr18:6,782,389...6,799,034 JBrowse link
G Crp C-reactive protein ISO protein:increased expression:serum: RGD PMID:6720266 RGD:9491754 NCBI chr13:87,694,062...87,695,978 JBrowse link
G F2 coagulation factor II, thrombin no_association ISO DNA:SNP: :20210G>A (human) RGD PMID:22800650 PMID:14994919 RGD:7387258, RGD:7394774 NCBI chr 3:98,051,958...98,065,246 JBrowse link
G F5 coagulation factor V onset
no_association		 ISO associated with Behcet Syndrome;DNA:missense mutation:cds:p.R506Q (human)
CTD Direct Evidence: marker/mechanism
DNA:missense mutation:cds:1691G>A (human)
DNA:SNP:cds:1691G>A (human)		 CTD
RGD		 PMID:12022286 PMID:10511031 PMID:16113792 PMID:10634550 RGD:7394767, RGD:7394778, RGD:7394773 NCBI chr13:79,046,657...79,116,247 JBrowse link
G Fgf2 fibroblast growth factor 2 IEP RGD PMID:10342378 RGD:8655593 NCBI chr 2:122,164,454...122,218,796 JBrowse link
G Il1b interleukin 1 beta IEP mRNA:increased expression:neuroretina, retinal pigment epithelium (rat) RGD PMID:21487926 RGD:5490120 NCBI chr 3:137,030,200...137,036,581 JBrowse link
G Il6 interleukin 6 IEP RGD PMID:21487926 RGD:5490120 NCBI chr 4:5,889,999...5,894,575 JBrowse link
G Itga2 integrin subunit alpha 2 susceptibility ISO DNA:snp, haplotype:cds:g.807C>T (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:12928694 PMID:12928694 RGD:8686430 NCBI chr 2:46,520,345...46,621,487 JBrowse link
G Kcnj10 potassium inwardly-rectifying channel, subfamily J, member 10 IEP RGD PMID:21487926 RGD:5490120 NCBI chr13:84,802,026...84,835,383 JBrowse link
G Mmp2 matrix metallopeptidase 2 ISO DNA:SNP:promoter:-1306C>T (rs243865) (human) RGD PMID:23791966 RGD:8657048 NCBI chr19:30,327,643...30,355,856 JBrowse link
G Mthfr methylenetetrahydrofolate reductase susceptibility
no_association		 ISO DNA:SNP: :677C>T(human)
DNA:missense mutation:cds:677C>T (human)
DNA:SNP: :1298A>C(human)		 RGD PMID:10485556 PMID:24250697 PMID:23289804 RGD:7387256, RGD:10449421, RGD:10449405 NCBI chr 5:163,748,346...163,768,141 JBrowse link
G Nrp1 neuropilin 1 ISS MouseDO NCBI chr19:73,256,557...73,411,705 JBrowse link
G Pon1 paraoxonase 1 susceptibility ISO DNA:missense mutation:cds:p.L55M (human)
protein:decreased activity:serum (human)		 RGD PMID:23441121 PMID:18084236 RGD:8547547, RGD:8547555 NCBI chr 4:34,261,312...34,292,327 JBrowse link
G Serpine1 serpin family E member 1 susceptibility ISO DNA:deletion:promoter:g.-676_-674delG (human)
protein:increased activity:plasma (human)		 RGD PMID:16244763 PMID:15213845 RGD:8547742, RGD:8547805 NCBI chr12:25,237,977...25,248,356 JBrowse link
G Serpinf1 serpin family F member 1 ISO protein:decreased expression:vitreous humor (human) RGD PMID:21275514 RGD:8554901 NCBI chr10:60,250,198...60,262,593 JBrowse link
G Vegfa vascular endothelial growth factor A IEP
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:16680105 PMID:21487926 RGD:5490120 NCBI chr 9:22,452,854...22,468,194 JBrowse link
G Vegfb vascular endothelial growth factor B IEP RGD PMID:21487926 RGD:5490120 NCBI chr 1:213,601,570...213,607,254 JBrowse link
sagittal sinus thrombosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F5 coagulation factor V ISO CTD Direct Evidence: marker/mechanism CTD PMID:18382986 NCBI chr13:79,046,657...79,116,247 JBrowse link
G Plau plasminogen activator, urokinase ISO CTD Direct Evidence: therapeutic CTD PMID:10668740 NCBI chr15:3,505,485...3,511,987 JBrowse link
G Pros1 protein S ISO CTD Direct Evidence: marker/mechanism CTD PMID:18382986 NCBI chr11:13,676,310...13,757,858 JBrowse link
thrombophlebitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir223 microRNA 223 IMP RGD PMID:32141571 RGD:26884338 NCBI chr  X:61,141,887...61,141,996 JBrowse link
G Pros1 protein S ISO RGD PMID:12907438 RGD:1578677 NCBI chr11:13,676,310...13,757,858 JBrowse link
G RT1-CE13 RT1 class I, locus CE13 ISO associated with Behcet Syndrome; DNA:polymorphisms:cds:HLA-B35, HLA-B51 (human, Turkish) RGD PMID:12372094 RGD:7364924 NCBI chr20:3,314,491...3,322,815 JBrowse link
Venous Thrombosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 treatment IDA RGD PMID:21095090 RGD:10449099 NCBI chr 3:10,299,264...10,338,464 JBrowse link
G Apoe apolipoprotein E ISO RGD PMID:22119245 RGD:6903200 NCBI chr 1:88,481,889...88,485,816 JBrowse link
G Arvcf ARVCF, delta catenin family member ISO ClinVar Annotator: match by term: Deep venous thrombosis ClinVar PMID:25741868 PMID:31064749 NCBI chr11:82,588,137...82,645,832 JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IEP mRNA, protein:increased expression:vein RGD PMID:18167211 RGD:2307053 NCBI chr10:67,503,077...67,504,875 JBrowse link
G Comt catechol-O-methyltransferase susceptibility ISO DNA:polymorphism: :324G>A
ClinVar Annotator: match by term: Deep venous thrombosis		 ClinVar
RGD		 PMID:25741868 PMID:31064749 PMID:18064318 RGD:2289709 NCBI chr11:96,072,371...96,091,956 JBrowse link
G Csf2 colony stimulating factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8120554 NCBI chr10:38,887,692...38,889,673 JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 IEP RGD PMID:7749835 RGD:5135275 NCBI chr14:17,310,790...17,312,250 JBrowse link
G Dgcr8 DGCR8 microprocessor complex subunit ISO ClinVar Annotator: match by term: Deep venous thrombosis ClinVar PMID:25741868 PMID:31064749 NCBI chr11:96,208,959...96,241,560 JBrowse link
G Epo erythropoietin ISO CTD Direct Evidence: marker/mechanism CTD PMID:12670338 PMID:17547733 NCBI chr12:19,204,258...19,207,948 JBrowse link
G F11 coagulation factor XI susceptibility ISO protein:increased activity:blood: RGD PMID:10706899 RGD:11041768 NCBI chr16:46,987,988...47,009,015 JBrowse link
G F12 coagulation factor XII susceptibility ISO DNA:polymorphism::46C>T(human)
associated with Pregnancy Complications; DNA:polymorphism::46C>T(human)		 RGD PMID:15116249 PMID:20141580 RGD:11041808, RGD:11041858 NCBI chr17:9,212,819...9,220,664 JBrowse link
G F13a1 coagulation factor XIII A1 chain susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:polymorphism:cds:p.V34L(human)		 CTD
RGD		 PMID:10365735 PMID:9920839 PMID:12358922 RGD:1581032, RGD:10450745 NCBI chr17:27,815,723...27,992,494 JBrowse link
G F13b coagulation factor XIII B chain ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Venous thrombosis, susceptibility to		 CTD
ClinVar		 PMID:12456499 PMID:16241947 PMID:25741868 NCBI chr13:51,130,908...51,156,383 JBrowse link
G F2 coagulation factor II, thrombin ISO
IMP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:9869612 PMID:12296757 PMID:19920886 PMID:9409269 PMID:23535565 RGD:1580342, RGD:10449430 NCBI chr 3:98,051,958...98,065,246 JBrowse link
G F3 coagulation factor III, tissue factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:14967414 NCBI chr 2:212,511,675...212,523,375 JBrowse link
G F5 coagulation factor V ISO DNA:missense mutation:cds:p.R506Q (human)
ClinVar Annotator: match by term: Deep venous thrombosis
CTD Direct Evidence: marker/mechanism
DNA:mutation: :1691G>A (human)
associated with Behcet Syndrome;DNA:SNP: :1691G>A (human)
associated with lupus erythematosus, systemic; DNA:polymorphism:cds:rs6025(human)		 ClinVar
CTD
RGD		 PMID:12296757 PMID:12827938 PMID:12865888 PMID:15033664 PMID:16875063 More... RGD:6893601, RGD:7394779, RGD:7394762, RGD:6893602 NCBI chr13:79,046,657...79,116,247 JBrowse link
G F7 coagulation factor VII treatment IMP
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:14967414 PMID:16378835 RGD:11041650 NCBI chr16:83,191,896...83,202,775 JBrowse link
G F8 coagulation factor VIII ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:16875063 PMID:15634269 RGD:1582359 NCBI chr18:140,848...172,330 JBrowse link
G Fga fibrinogen alpha chain ISO
IEP		 DNA:SNP: :rs6050 (human)
protein:increased expression:peripheral blood (rat)
ClinVar Annotator: match by term: Deep vein thrombosis		 ClinVar
RGD		 PMID:8473507 PMID:8636415 PMID:25741868 PMID:34355501 PMID:22353194 More... RGD:5688756, RGD:7207783 NCBI chr 2:170,672,169...170,679,572 JBrowse link
G Fgb fibrinogen beta chain ISO ClinVar Annotator: match by term: Deep vein thrombosis | ClinVar Annotator: match by term: Deep venous thrombosis ClinVar PMID:12573244 PMID:15795540 PMID:25741868 PMID:28492532 PMID:31064749 NCBI chr 2:168,394,901...168,402,863 JBrowse link
G Gnb1l G protein subunit beta 1 like ISO ClinVar Annotator: match by term: Deep venous thrombosis ClinVar PMID:25741868 PMID:31064749 NCBI chr11:82,425,301...82,507,836 JBrowse link
G Gp1bb glycoprotein Ib platelet subunit beta ISO ClinVar Annotator: match by term: Deep venous thrombosis ClinVar PMID:25741868 PMID:31064749 NCBI chr11:82,378,216...82,379,393 JBrowse link
G Gp6 glycoprotein VI treatment ISO protein:increased expression:plasma (human) RGD PMID:25253166 PMID:16254207 RGD:401794452, RGD:401824681 NCBI chr 1:78,471,900...78,535,374 JBrowse link
G Gpx1 glutathione peroxidase 1 ISO RGD PMID:23426106 RGD:11352755 NCBI chr 8:117,905,462...117,906,588 JBrowse link
G Habp2 hyaluronan binding protein 2 ISO DNA:SNP: :p.G534E (rs7080536) (human) RGD PMID:22421107 RGD:11353820 NCBI chr 1:255,315,870...255,350,161 JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:36162953 NCBI chr 6:98,357,788...98,405,068 JBrowse link
G Hp haptoglobin ISO associated with Pulmonary Embolism;protein:increased expression:serum RGD PMID:17203959 RGD:1626365 NCBI chr19:54,449,151...54,453,701 JBrowse link
G Il10 interleukin 10 susceptibility ISO RGD PMID:16807647 RGD:1598472 NCBI chr13:45,024,921...45,029,586 JBrowse link
G Il18 interleukin 18 IEP protein:increased expression:serum RGD PMID:22318348 RGD:8655957 NCBI chr 8:59,802,072...59,829,275 JBrowse link
G Il1a interleukin 1 alpha IEP RGD PMID:17651586 RGD:2311092 NCBI chr 3:136,979,804...136,990,236 JBrowse link
G Il1b interleukin 1 beta IEP RGD PMID:17651586 RGD:2311092 NCBI chr 3:137,030,200...137,036,581 JBrowse link
G Il1rn interleukin 1 receptor antagonist susceptibility ISO DNA:haplotype::rs2232354(human) RGD PMID:17413037 RGD:11528540 NCBI chr 3:27,509,836...27,525,738 JBrowse link
G Itga2 integrin subunit alpha 2 no_association ISO RGD PMID:16380674 RGD:1582295 NCBI chr 2:46,520,345...46,621,487 JBrowse link
G Itgb3 integrin subunit beta 3 susceptibility ISO associated with Behcet Syndrome; DNA:polymorphism: : RGD PMID:21813062 RGD:8693342 NCBI chr10:90,009,927...90,067,787 JBrowse link
G Jak2 Janus kinase 2 no_association ISO DNA:SNPs, haplotype: :rs12342421, rs12343867 (human)
DNA:SNP: :rs10974944 (human)
DNA:mutation: :p.V617F (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:20434300 PMID:23845539 PMID:23845539 PMID:17059429 RGD:10449376, RGD:10449376, RGD:10449391 NCBI chr 1:236,408,905...236,468,769 JBrowse link
G Kdr kinase insert domain receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:26600200 NCBI chr14:32,572,031...32,615,204 JBrowse link
G Klhl22 kelch-like family member 22 ISO ClinVar Annotator: match by term: Deep venous thrombosis ClinVar PMID:25741868 PMID:31064749 NCBI chr11:83,190,891...83,231,746 JBrowse link
G Med15 mediator complex subunit 15 ISO ClinVar Annotator: match by term: Deep venous thrombosis ClinVar PMID:25741868 PMID:31064749 NCBI chr11:83,280,722...83,356,006 JBrowse link
G Mmp14 matrix metallopeptidase 14 ISO RGD PMID:16171603 RGD:1582570 NCBI chr15:27,887,795...27,897,020 JBrowse link
G Mmp2 matrix metallopeptidase 2 IEP
IDA		 RGD PMID:20515599 PMID:16171603 RGD:2325775, RGD:1582570 NCBI chr19:30,327,643...30,355,856 JBrowse link
G Mmp3 matrix metallopeptidase 3 IEP RGD PMID:20515599 RGD:2325775 NCBI chr 8:12,925,267...12,938,828 JBrowse link
G Mmp9 matrix metallopeptidase 9 HEP
ISO		 mRNA:increased expression:femoral vein (rat) RGD PMID:20515599 PMID:16920980 RGD:2325775, RGD:1582648 NCBI chr 3:174,103,474...174,111,434 JBrowse link
G Mthfr methylenetetrahydrofolate reductase no_association
susceptibility		 ISO DNA:transition:cds:g.677C>T (human)
CTD Direct Evidence: marker/mechanism
DNA:transition: :677C>T (human)
associated with Lupus Erythematosus, Systemic; DNA:transition, transversion:cds:g.677C>T rs1801133, g.1298A>C rs1801131 (human)		 CTD
RGD		 PMID:19123085 PMID:10929044 PMID:12442281 PMID:10792297 PMID:22707612 RGD:1580590, RGD:10449394, RGD:6893655, RGD:6893602 NCBI chr 5:163,748,346...163,768,141 JBrowse link
G Nos3 nitric oxide synthase 3 susceptibility ISO associated with orthopedic surgery;DNA:SNP::rs1799983(human) RGD PMID:23922896 RGD:11533639 NCBI chr 4:11,686,088...11,706,604 JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 susceptibility ISO DNA:missense mutation:cds:p.L125V (human) RGD PMID:25846278 RGD:11541089 NCBI chr10:92,090,263...92,152,002 JBrowse link
G Pf4 platelet factor 4 ISO associated with Wounds and Injuries;mRNA:increased expression:blood RGD PMID:32347511 RGD:329901817 NCBI chr14:17,582,477...17,583,392 JBrowse link
G Pi4ka phosphatidylinositol 4-kinase alpha ISO ClinVar Annotator: match by term: Deep venous thrombosis ClinVar PMID:25741868 PMID:31064749 NCBI chr11:97,113,390...97,234,374 JBrowse link
G Pigm phosphatidylinositol glycan anchor biosynthesis, class M ISO CTD Direct Evidence: marker/mechanism CTD PMID:16767100 NCBI chr13:84,838,329...84,842,026 JBrowse link
G Plat plasminogen activator, tissue type ISO CTD Direct Evidence: therapeutic
ClinVar Annotator: match by term: Deep venous thrombosis		 CTD
ClinVar		 PMID:11144008 PMID:15557913 PMID:19415734 PMID:25741868 PMID:31064749 NCBI chr16:75,943,061...76,022,037 JBrowse link
G Plau plasminogen activator, urokinase ISO CTD Direct Evidence: therapeutic CTD PMID:3161212 PMID:3488869 PMID:6359570 PMID:15557913 NCBI chr15:3,505,485...3,511,987 JBrowse link
G Plg plasminogen ISO CTD Direct Evidence: therapeutic
ClinVar Annotator: match by term: Deep vein thrombosis | ClinVar Annotator: match by term: Deep venous thrombosis		 CTD
ClinVar		 PMID:7215189 PMID:10233898 PMID:12850227 PMID:12876630 PMID:15269832 More... NCBI chr 1:48,325,186...48,367,643 JBrowse link
G Ppbp pro-platelet basic protein ameliorates ISO associated with Wounds and Injuries;mRNA:increased expression:blood RGD PMID:32347511 PMID:23550035 RGD:329901817, RGD:401794958 NCBI chr14:17,586,495...17,587,299 JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa ISO DNA:missense mutation:cds:p.Q184H (human)
DNA:silent mutation, missense mutation:cds:g.66C>T, p.R147W (human)
DNA:missense mutations: :p.D297H, p.V420L (human)
DNA:missense mutation: :c.565C>T (rs146922325) (human)
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Deep vein thrombosis | ClinVar Annotator: match by term: Deep venous thrombosis		 CTD
ClinVar
RGD		 PMID:1868249 PMID:7482420 PMID:8128429 PMID:8499565 PMID:8845458 More... RGD:1578515, RGD:1578391, RGD:11035247, RGD:11099989, RGD:11099990, RGD:11100014 NCBI chr18:24,038,596...24,049,061 JBrowse link
G Pros1 protein S ISO DNA:missense mutation:cds:p.G295V (human)
ClinVar Annotator: match by term: Deep vein thrombosis		 ClinVar
RGD		 PMID:7803790 PMID:12351389 PMID:20880255 PMID:22261441 PMID:25741868 More... RGD:9743896 NCBI chr11:13,676,310...13,757,858 JBrowse link
G Ranbp1 RAN binding protein 1 ISO ClinVar Annotator: match by term: Deep venous thrombosis ClinVar PMID:25741868 PMID:31064749 NCBI chr11:96,246,912...96,255,145 JBrowse link
G Rtn4r reticulon 4 receptor ISO ClinVar Annotator: match by term: Deep venous thrombosis ClinVar PMID:25741868 PMID:31064749 NCBI chr11:82,844,309...82,869,251 JBrowse link
G Scarf2 scavenger receptor class F, member 2 ISO ClinVar Annotator: match by term: Deep venous thrombosis ClinVar PMID:25741868 PMID:31064749 NCBI chr11:83,175,956...83,187,415 JBrowse link
G Septin5 septin 5 ISO ClinVar Annotator: match by term: Deep venous thrombosis ClinVar PMID:25741868 PMID:31064749 NCBI chr11:82,373,601...82,379,393 JBrowse link
G Serpina10 serpin family A member 10 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Venous thrombosis, susceptibility to		 CTD
ClinVar		 PMID:15461625 PMID:25741868 NCBI chr 6:122,756,106...122,764,544 JBrowse link
G Serpina5 serpin family A member 5 susceptibility ISO protein:increased expression:plasma (human) RGD PMID:12139754 RGD:1580299 NCBI chr 6:123,009,224...123,028,412 JBrowse link
G Serpinc1 serpin family C member 1 ISO ClinVar Annotator: match by term: Deep venous thrombosis
CTD Direct Evidence: marker/mechanism
DNA:missense mutations: :multiple		 ClinVar
CTD
RGD		 PMID:55783 PMID:1483705 PMID:1555650 PMID:1977621 PMID:2336381 More... RGD:11035247, RGD:11035248 NCBI chr13:75,790,558...75,804,826 JBrowse link
G Serpind1 serpin family D member 1 ISO ClinVar Annotator: match by term: Deep venous thrombosis ClinVar PMID:25741868 PMID:31064749 NCBI chr11:83,664,517...83,675,593 JBrowse link
G Serpine1 serpin family E member 1 ISO
IMP
IEP		 DNA:deletion:promoter:g.-676_-674delG (human)
mRNA:increased expression:femoral vein (rat)		 RGD PMID:14653439 PMID:9535178 PMID:26535698 RGD:1580132, RGD:8547875, RGD:11060966 NCBI chr12:25,237,977...25,248,356 JBrowse link
G Tango2 transport and golgi organization 2 homolog ISO ClinVar Annotator: match by term: Deep venous thrombosis ClinVar PMID:25741868 PMID:31064749 NCBI chr11:82,645,978...82,692,574 JBrowse link
G Tbx1 T-box transcription factor 1 ISO ClinVar Annotator: match by term: Deep venous thrombosis ClinVar PMID:25741868 PMID:31064749 NCBI chr11:82,409,275...82,419,058 JBrowse link
G Tbxa2r thromboxane A2 receptor treatment IMP RGD PMID:7848332 RGD:11059887 NCBI chr 7:9,034,077...9,041,489 JBrowse link
G Tfpi tissue factor pathway inhibitor ISO protein:increased expression:plasma:
CTD Direct Evidence: therapeutic		 CTD
RGD		 PMID:18480984 PMID:18600090 PMID:17973652 PMID:12560220 RGD:11060130, RGD:11060257, RGD:11060137 NCBI chr 3:89,939,862...89,989,253 JBrowse link
G Trmt2a tRNA methyltransferase 2 homolog A ISO ClinVar Annotator: match by term: Deep venous thrombosis ClinVar PMID:25741868 PMID:31064749 NCBI chr11:82,737,689...82,742,423 JBrowse link
G Txnrd2 thioredoxin reductase 2 ISO ClinVar Annotator: match by term: Deep venous thrombosis ClinVar PMID:25741868 PMID:31064749 NCBI chr11:82,519,996...82,568,156 JBrowse link
G Vcam1 vascular cell adhesion molecule 1 IEP protein:increased expression:thrombus, vein RGD PMID:23199547 RGD:7207783 NCBI chr 2:206,723,050...206,742,783 JBrowse link
G Zdhhc8 zinc finger DHHC-type palmitoyltransferase 8 ISO ClinVar Annotator: match by term: Deep venous thrombosis ClinVar PMID:25741868 PMID:31064749 NCBI chr11:82,755,110...82,769,280 JBrowse link
G Zim1 zinc finger, imprinted 1 ISO ClinVar Annotator: match by term: Deep venous thrombosis ClinVar PMID:25741868 PMID:31064749 NCBI chr 1:67,132,076...67,157,843 JBrowse link
venous tributary occlusion of retina term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itga2 integrin subunit alpha 2 no_association ISO DNA:snp:cds:g.807C>T (human) RGD PMID:16157382 RGD:1582301 NCBI chr 2:46,520,345...46,621,487 JBrowse link
G Serpinf1 serpin family F member 1 ISO protein:decreased expression:vitreous humor (human) RGD PMID:20714746 RGD:8554903 NCBI chr10:60,250,198...60,262,593 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19139
    disease of anatomical entity 18450
      cardiovascular system disease 5541
        vascular disease 4023
          thrombosis 146
            Arterial Thrombosis 11
            Dysfibrinogenemia Causing Recurrent Thrombosis 0
            Venous Thrombosis + 90
            coronary thrombosis 3
            heparin cofactor II deficiency 2
            intracranial thrombosis + 20
            livedoid vasculitis 0
Path 2
Term Annotations click to browse term
  disease 19139
    disease of anatomical entity 18450
      cardiovascular system disease 5541
        vascular disease 4023
          Embolism and Thrombosis 170
            thrombosis 146
              Arterial Thrombosis 11
              Dysfibrinogenemia Causing Recurrent Thrombosis 0
              Venous Thrombosis + 90
              coronary thrombosis 3
              heparin cofactor II deficiency 2
              intracranial thrombosis + 20
              livedoid vasculitis 0
paths to the root