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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:purpura fulminans
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Accession:DOID:0060538 term browser browse the term
Definition:A purpura characterized by blood spots, bruising and discoloration of the skin resulting from coagulation in small blood vessels within the skin and rapidly leading to skin necrosis and disseminated intravascular coagulation. It is often fatal. (DO)
Synonyms:exact_synonym: purpura gangrenosa
 primary_id: MESH:D055665
 xref: EFO:1001913;   ICD10CM:D65;   ORDO:49566



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purpura fulminans term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PROC protein C, inactivator of coagulation factors Va and VIIIa ISO CTD Direct Evidence: marker/mechanism CTD PMID:18376272 NCBI chr15:25,043,543...25,054,310
Ensembl chr15:25,043,545...25,056,595
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Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17412
    Pathological Conditions, Signs and Symptoms 11799
      Signs and Symptoms 9738
        Skin Manifestations 121
          purpura 47
            purpura fulminans 1
Path 2
Term Annotations click to browse term
  disease 17412
    disease of anatomical entity 14873
      Hemic and Lymphatic Diseases 3610
        hematopoietic system disease 3134
          blood coagulation disease 894
            hemorrhagic disease 851
              purpura 47
                purpura fulminans 1
paths to the root