Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:respiratory allergy
go back to main search page
Accession:DOID:0060496 term browser browse the term
Definition:An allergic disease that is located_in the respiratory tract. (DO)
Synonyms:exact_synonym: airway allergy;   airway hyper responsiveness;   respiratory hypersensitivities;   respiratory hypersensitivity
 related_synonym: allergic lung disease
 primary_id: MESH:D012130


GViewer not supported for the selected species.

show annotations for term's descendants           Sort by:
respiratory allergy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL11 C-C motif chemokine ligand 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17085522 NCBI chr16:27,792,699...27,796,437
Ensembl chr16:27,794,033...27,796,460
JBrowse link
G CCL8 C-C motif chemokine ligand 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17085522 NCBI chr16:27,821,149...27,823,919
Ensembl chr16:27,821,970...27,823,528
JBrowse link
G CCR3 C-C motif chemokine receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20022477 NCBI chr22:7,648,410...7,698,523
Ensembl chr22:7,697,068...7,698,135
JBrowse link
G CLDN4 claudin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30608172 NCBI chr28:9,242,054...9,244,972
Ensembl chr28:9,242,909...9,243,538
JBrowse link
G CLDN5 claudin 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30608172 NCBI chr19:6,227,881...6,230,199
Ensembl chr19:6,228,965...6,229,621
JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 ISO CTD Direct Evidence: therapeutic CTD PMID:23056391 NCBI chr 7:22,327,041...22,329,405
Ensembl chr 7:22,569,355...22,569,900
Ensembl chr 7:22,569,355...22,569,900
JBrowse link
G CXCL6 C-X-C motif chemokine ligand 6 ISO mRNA:increased expression:lung RGD PMID:18417511 RGD:5135242 NCBI chr 7:22,291,949...22,294,191
Ensembl chr 7:22,292,045...22,294,207
JBrowse link
G F2RL1 F2R like trypsin receptor 1 ISO RGD PMID:20186875 RGD:4892588 NCBI chr 4:71,095,446...71,109,832
Ensembl chr 4:71,095,500...71,110,005
JBrowse link
G HRH1 histamine receptor H1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12095164 NCBI chr22:47,187,156...47,298,761
Ensembl chr22:47,295,011...47,296,471
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24211530 NCBI chr12:12,920,705...12,925,888
Ensembl chr12:12,920,710...12,927,431
JBrowse link
G IL10 interleukin 10 ISO RGD PMID:20583974 RGD:4140460 NCBI chr25:22,590,389...22,595,877
Ensembl chr25:22,590,962...22,594,836
JBrowse link
G IL13 interleukin 13 susceptibility ISO DNA:SNP, missense mutation:promoter, exon:-1112C>T, p.R130Q (human)
mRNA:increased expression:lung
RGD PMID:18849614 PMID:19564030 RGD:4145637 RGD:8549507 NCBI chr23:35,475,762...35,479,419
Ensembl chr23:35,476,490...35,478,869
JBrowse link
G IL15 interleukin 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18394133 NCBI chr 7:88,548,773...88,644,977
Ensembl chr 7:88,548,671...88,645,488
JBrowse link
G IL1A interleukin 1 alpha ISO RGD PMID:12663678 RGD:4143222 NCBI chr14:15,789,710...15,801,938
Ensembl chr14:15,789,013...15,796,611
JBrowse link
G IL1B interleukin 1 beta ISO RGD PMID:12663678 RGD:4143222 NCBI chr14:15,844,628...15,852,652
Ensembl chr14:15,844,672...15,850,729
JBrowse link
G IL1RL1 interleukin 1 receptor like 1 ISO associated with Fungal Lung Diseases RGD PMID:25746970 RGD:39938968 NCBI chr14:5,966,551...6,020,391
Ensembl chr14:6,005,061...6,020,265
JBrowse link
G IL1RN interleukin 1 receptor antagonist ISO RGD PMID:12663678 RGD:4143222 NCBI chr14:16,136,667...16,152,451
Ensembl chr14:16,146,333...16,151,326
JBrowse link
G IL27 interleukin 27 ISO RGD PMID:20817868 RGD:4145651 NCBI chr 5:26,348,559...26,358,028
Ensembl chr 5:26,348,848...26,356,360
JBrowse link
G IL33 interleukin 33 treatment ISO RGD PMID:25424936 RGD:40400692 NCBI chr12:73,235,585...73,283,665
Ensembl chr12:73,237,406...73,252,436
JBrowse link
G IL4 interleukin 4 ISO associated with Pneumonia, Pneumocystis carinii
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:18394133 PMID:21343358 RGD:5128506 NCBI chr23:35,492,158...35,501,349
Ensembl chr23:35,492,939...35,501,258
JBrowse link
G IL6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18394133 NCBI chr21:35,577,513...35,582,385
Ensembl chr21:35,577,939...35,582,237
JBrowse link
G LOC103233044 metallothionein-1X ISO CTD Direct Evidence: marker/mechanism CTD PMID:17085522 NCBI chr 5:42,637,027...42,638,751
Ensembl chr 5:42,637,113...42,638,611
JBrowse link
G LOC103242760 C-C motif chemokine 16 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17085522 NCBI chr16:29,473,639...29,477,861
Ensembl chr16:29,452,308...29,458,007
Ensembl chr16:29,452,308...29,458,007
Ensembl chr16:29,452,308...29,458,007
JBrowse link
G MBL2 mannose binding lectin 2 susceptibility ISO DNA:SNP:intron:1011G>A(human) RGD PMID:16487239 RGD:8693711 NCBI chr 9:78,389,534...78,394,753
Ensembl chr 9:78,389,947...78,396,079
JBrowse link
G NOS2 nitric oxide synthase 2 treatment ISO RGD PMID:19800904 PMID:21983654 RGD:4891497 RGD:8549812 NCBI chr16:21,533,011...21,576,645
Ensembl chr16:21,533,484...21,574,257
JBrowse link
G NOS3 nitric oxide synthase 3 ISO DNA:polymorphism: :c. -786C>T (human) RGD PMID:18086269 RGD:4892054 NCBI chr21:119,174,829...119,196,840 JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18441283 NCBI chr11:6,977,480...6,994,525
Ensembl chr11:6,984,710...6,994,545
JBrowse link
G SERPINE1 serpin family E member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24211530 NCBI chr28:12,047,520...12,060,662
Ensembl chr28:12,047,529...12,060,202
JBrowse link
G SLC30A4 solute carrier family 30 member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17085522 NCBI chr26:37,692,164...37,732,102
Ensembl chr26:37,692,219...37,731,292
JBrowse link
G SLC39A1 solute carrier family 39 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17085522 NCBI chr20:9,847,928...9,852,998
Ensembl chr20:9,847,968...9,853,413
JBrowse link
G SLC39A14 solute carrier family 39 member 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17085522 NCBI chr 8:20,446,756...20,502,585 JBrowse link
G SLC39A4 solute carrier family 39 member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17085522 NCBI chr 8:138,622,100...138,626,749
Ensembl chr 8:138,622,224...138,626,376
JBrowse link
G TLR4 toll like receptor 4 susceptibility ISO DNA:polymorphisms,haplotype: :−2027A>G, ¿1608T>C(human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:10835634 PMID:21704886 RGD:7800728 NCBI chr12:21,873,762...21,885,562
Ensembl chr12:21,871,773...21,885,515
JBrowse link
G TNF tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:18394133
G TSLP thymic stromal lymphopoietin ISO CTD Direct Evidence: therapeutic CTD PMID:28329851 NCBI chr23:14,419,820...14,423,331 JBrowse link
G UPP1 uridine phosphorylase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24211530 NCBI chr21:10,686,600...10,707,181
Ensembl chr21:10,686,093...10,706,347
JBrowse link
G VEGFA vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:30608172 NCBI chr17:28,377,959...28,394,508 JBrowse link
acute asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CXCL8 C-X-C motif chemokine ligand 8 treatment ISO RGD PMID:30059697 RGD:39939057 NCBI chr 7:22,202,497...22,205,730
Ensembl chr 7:22,202,527...22,204,068
JBrowse link
allergic asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL26 C-C motif chemokine ligand 26 treatment ISO RGD PMID:25530546 RGD:11081163 NCBI chr28:10,036,177...10,038,962
Ensembl chr28:10,036,337...10,038,875
JBrowse link
G EPX eosinophil peroxidase ISO protein:increased expression:urine: RGD PMID:11846868 RGD:13506893 NCBI chr16:35,196,433...35,208,269
Ensembl chr16:35,192,971...35,207,874
JBrowse link
G IL25 interleukin 25 treatment ISO RGD PMID:17889290 RGD:40902975 NCBI chr29:23,742,377...23,747,902
Ensembl chr29:23,744,449...23,747,176
JBrowse link
G LOC103232241 cysteinyl leukotriene receptor 1 treatment ISO RGD PMID:23933317 RGD:40903070 NCBI chr  X:67,218,777...67,300,655
Ensembl chr  X:67,220,048...67,221,061
JBrowse link
G MHC-DPA1 major histocompatibility complex, class II, DP alpha 1 susceptibility ISO DNA:polymorphism: RGD PMID:28380482 RGD:13506910 NCBI chr17:39,009,361...39,017,978 JBrowse link
G MHC-DPB1 major histocompatibility complex, class II, DP beta 1 susceptibility ISO DNA:polymorphism: RGD PMID:28380482 RGD:13506910 NCBI chr17:38,996,329...39,007,097 JBrowse link
G TREM1 triggering receptor expressed on myeloid cells 1 exacerbates ISO RGD PMID:21592044 RGD:126928124 NCBI chr17:30,873,647...30,885,292
Ensembl chr17:30,873,666...30,886,967
JBrowse link
allergic bronchopulmonary aspergillosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL17 C-C motif chemokine ligand 17 ISO associated with Cystic Fibrosis RGD PMID:17898016 RGD:4145612 NCBI chr 5:43,343,525...43,350,096
Ensembl chr 5:43,346,329...43,348,599
JBrowse link
G CCR1 C-C motif chemokine receptor 1 ISO RGD PMID:15951834 RGD:5688155 NCBI chr22:7,634,205...7,641,380 JBrowse link
G CCR2 C-C motif chemokine receptor 2 ISO RGD PMID:10946288 RGD:8661731 NCBI chr22:7,795,192...7,801,242
Ensembl chr22:7,798,646...7,799,728
JBrowse link
G CFTR CF transmembrane conductance regulator ISO DNA:mutations: : RGD PMID:11243954 RGD:4140482 NCBI chr21:86,154,313...86,332,436 JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO RGD PMID:7743671 RGD:8547590 NCBI chr 6:9,320,991...9,338,125
Ensembl chr 6:9,322,550...9,338,263
JBrowse link
G IL1A interleukin 1 alpha ISO RGD PMID:8699818 RGD:7794730 NCBI chr14:15,789,710...15,801,938
Ensembl chr14:15,789,013...15,796,611
JBrowse link
G MBL2 mannose binding lectin 2 susceptibility ISO Chronic Necrotizing Pulmonary Aspergillosis; DNA:missense mutation:exon:p.R52C (human)
DNA:SNP:intron:1011G>A(human)
RGD PMID:11474427 PMID:16487239 RGD:4889577 RGD:8693711 NCBI chr 9:78,389,534...78,394,753
Ensembl chr 9:78,389,947...78,396,079
JBrowse link
G TNF tumor necrosis factor ISO RGD PMID:8699818 RGD:7794730
G TNFRSF1A TNF receptor superfamily member 1A susceptibility ISO DNA:snps:5' utr, exon:g.-609G>T rs4149570, g.36A>G rs767455 (human) RGD PMID:20646338 RGD:5131174 NCBI chr11:6,364,544...6,378,880
Ensembl chr11:6,364,330...6,378,902
JBrowse link
allergic rhinitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 severity ISO DNA:snp:exon:c.1236C>T (human) RGD PMID:24040855 RGD:8657076 NCBI chr21:61,211,044...61,430,691
Ensembl chr21:61,322,748...61,529,274
JBrowse link
G BCL2 BCL2 apoptosis regulator ISO mRNA, protein:increased expression:nasal mucosa (rat) RGD PMID:15362690 RGD:11522724 NCBI chr18:16,440,560...16,643,187
Ensembl chr18:16,441,733...16,637,895
JBrowse link
G CAT catalase ISO CTD Direct Evidence: marker/mechanism CTD PMID:29028686 NCBI chr 1:30,792,533...30,828,920
Ensembl chr 1:30,792,399...30,829,592
JBrowse link
G CCL11 C-C motif chemokine ligand 11 treatment ISO RGD PMID:23089405 RGD:7248414 NCBI chr16:27,792,699...27,796,437
Ensembl chr16:27,794,033...27,796,460
JBrowse link
G CCL26 C-C motif chemokine ligand 26 ISO protein:increased expression:oronasal secretion (human) RGD PMID:23883806 RGD:7364793 NCBI chr28:10,036,177...10,038,962
Ensembl chr28:10,036,337...10,038,875
JBrowse link
G CD40 CD40 molecule ISO protein:increased expression:lymphocyte RGD PMID:19086656 RGD:8547782 NCBI chr 2:17,753,713...17,765,134
Ensembl chr 2:17,753,394...17,764,566
JBrowse link
G CD40LG CD40 ligand ISO protein:increased expression:lymphocyte RGD PMID:19086656 RGD:8547782 NCBI chr  X:111,655,301...111,667,602
Ensembl chr  X:111,655,397...111,666,639
JBrowse link
G CLDN3 claudin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:33441633 NCBI chr28:9,301,312...9,303,496
Ensembl chr28:9,302,446...9,303,108
JBrowse link
G CLDN7 claudin 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:33441633 NCBI chr16:6,632,695...6,635,994
Ensembl chr16:6,630,412...6,635,327
JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 treatment ISO RGD PMID:10436391 RGD:11344920 NCBI chr10:89,637,176...89,644,436
Ensembl chr10:89,638,314...89,642,344
JBrowse link
G FCGR3A Fc fragment of IgG receptor IIIa susceptibility ISO DNA:polymorphism:exon:p.F158V(rs396991)(human) RGD PMID:18199088 RGD:5508449 NCBI chr20:2,466,492...2,475,579 JBrowse link
G GRIA1 glutamate ionotropic receptor AMPA type subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34624383 NCBI chr23:55,944,128...56,265,748
Ensembl chr23:56,101,294...56,265,849
JBrowse link
G GRIA2 glutamate ionotropic receptor AMPA type subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34624383 NCBI chr 7:103,808,789...103,957,947
Ensembl chr 7:103,808,797...103,953,040
JBrowse link
G HMOX1 heme oxygenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36127783 NCBI chr19:18,144,466...18,157,944
Ensembl chr19:18,144,545...18,157,971
JBrowse link
G HRH1 histamine receptor H1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23333628 NCBI chr22:47,187,156...47,298,761
Ensembl chr22:47,295,011...47,296,471
JBrowse link
G IFNG interferon gamma treatment ISO associated with Asthma
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:12787306 PMID:18510219 PMID:29871060 RGD:10755770 RGD:7829803 NCBI chr11:63,785,493...63,791,071
Ensembl chr11:63,786,041...63,790,473
JBrowse link
G IL10 interleukin 10 treatment ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:23253209 PMID:23883806 PMID:36127783 RGD:7364793 RGD:7364818 NCBI chr25:22,590,389...22,595,877
Ensembl chr25:22,590,962...22,594,836
JBrowse link
G IL13 interleukin 13 susceptibility
no_association
ISO CTD Direct Evidence: marker/mechanism
DNA:SNPs:promoter, cds:-1112C>T, p.R130Q (rs1800925, rs20541) (human)
OMIM
CTD
RGD
PMID:12928861 RGD:8549516 NCBI chr23:35,475,762...35,479,419
Ensembl chr23:35,476,490...35,478,869
JBrowse link
G IL13RA2 interleukin 13 receptor subunit alpha 2 ISO protein:increased expression:serum RGD PMID:21462799 RGD:8549521 NCBI chr  X:102,589,947...102,628,853
Ensembl chr  X:102,590,045...102,603,260
JBrowse link
G IL17A interleukin 17A susceptibility ISO mRNA:increased expression:peripheral blood mononuclear cell (human)
DNA:snp:promoter:c.-444A>G (human)
RGD PMID:21535180 PMID:22507625 RGD:5147409 RGD:9068429 NCBI chr17:20,314,082...20,319,917
Ensembl chr17:20,315,773...20,318,785
JBrowse link
G IL18 interleukin 18 no_association
severity
ISO DNA:SNP:promoter:-140C>G (rs360721) (human)
DNA:SNP:promoter:-137G>C (rs187238) (human)
RGD PMID:22840759 RGD:8655914 NCBI chr 1:103,485,868...103,511,632
Ensembl chr 1:103,482,083...103,510,150
JBrowse link
G IL1B interleukin 1 beta ISO protein:increased expression:nasal mucus RGD PMID:7750009 RGD:7401199 NCBI chr14:15,844,628...15,852,652
Ensembl chr14:15,844,672...15,850,729
JBrowse link
G IL2 interleukin 2 ISO RGD PMID:12592663 RGD:8662963 NCBI chr 7:69,729,635...69,736,279
Ensembl chr 7:69,730,282...69,734,969
JBrowse link
G IL4 interleukin 4 treatment ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:8908280 PMID:9893928 PMID:14653048 PMID:24620662 PMID:36127783 RGD:11522769 RGD:7829796 RGD:7829802 RGD:7829827 NCBI chr23:35,492,158...35,501,349
Ensembl chr23:35,492,939...35,501,258
JBrowse link
G IL5 interleukin 5 treatment ISO RGD PMID:23934070 PMID:24620662 RGD:11354976 RGD:11522769 NCBI chr23:35,360,143...35,375,169
Ensembl chr23:35,360,506...35,362,178
JBrowse link
G ITGB2 integrin subunit beta 2 treatment ISO RGD PMID:12046991 RGD:9698435 NCBI chr 2:88,597,554...88,644,890
Ensembl chr 2:88,597,556...88,624,025
JBrowse link
G MRC1 mannose receptor C-type 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36127783 NCBI chr 9:17,751,053...17,849,258
Ensembl chr 9:17,751,133...17,849,406
JBrowse link
G MUC1 mucin 1, cell surface associated severity ISO mRNA,protein:decreased expression:nasal mucosa RGD PMID:31425778 RGD:127345100 NCBI chr20:8,641,701...8,646,739
Ensembl chr20:8,642,842...8,646,962
JBrowse link
G MUC5AC mucin 5AC, oligomeric mucus/gel-forming ISO mRNA, protein:increased expression:nasal cavity epithelium RGD PMID:22972875 RGD:7364746 NCBI chr 1:981,515...1,018,242 JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 ISO mRNA:increased expression:nasal mucosa (human) RGD PMID:23858718 RGD:8547523 NCBI chr 5:36,492,158...36,531,766
Ensembl chr 5:36,496,414...36,530,499
JBrowse link
G OCLN occludin ISO CTD Direct Evidence: marker/mechanism CTD PMID:33441633 NCBI chr 4:65,581,943...65,641,516
Ensembl chr 4:65,582,460...65,644,787
JBrowse link
G PON1 paraoxonase 1 severity ISO protein:decreased activity:plasma (human) RGD PMID:23406590 RGD:8547583 NCBI chr21:53,713,434...53,739,658
Ensembl chr21:53,714,012...53,739,875
JBrowse link
G PRKG1 protein kinase cGMP-dependent 1 ISO protein:increased expression:nasal cavity epithelium RGD PMID:24012634 RGD:7775060 NCBI chr 9:78,858,269...80,188,163 JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16979129 NCBI chr25:42,733,535...42,742,463
Ensembl chr25:42,734,771...42,742,429
JBrowse link
G SCGB1A1 secretoglobin family 1A member 1 ISO mRNA:decreased expression:nasal mucosa, lung RGD PMID:17882576 RGD:5144135 NCBI chr 1:11,470,091...11,474,915
Ensembl chr 1:11,470,195...11,474,149
JBrowse link
G SCGB3A2 secretoglobin family 3A member 2 susceptibility ISO DNA:SNP: :rs7726552 (human) RGD PMID:21410962 RGD:5144225 NCBI chr23:50,327,428...50,417,518
Ensembl chr23:50,414,139...50,417,373
JBrowse link
G SERPINE1 serpin family E member 1 ISO mRNA:increased expression:nasal mucosa (mouse) RGD PMID:21339035 RGD:8547809 NCBI chr28:12,047,520...12,060,662
Ensembl chr28:12,047,529...12,060,202
JBrowse link
G TACR1 tachykinin receptor 1 ISO mRNA:increased expression:nasal mucosa RGD PMID:12768696 RGD:5147835 NCBI chr14:32,080,319...32,236,556
Ensembl chr14:32,083,615...32,233,596
JBrowse link
G TGFB1 transforming growth factor beta 1 treatment ISO RGD PMID:31368266 RGD:14995445 NCBI chr 6:35,651,583...35,674,387
Ensembl chr 6:35,648,677...35,674,365
JBrowse link
G TLR2 toll like receptor 2 severity ISO DNA:polymorphism:cds:p.R753Q(human)
protein:increased expression:neutrophil:
mRNA:decreased expression:nasal mucosa:
RGD PMID:18219831 PMID:18381801 PMID:22402138 PMID:22555057 RGD:7800732 RGD:7800742 RGD:8552972 RGD:8552993 NCBI chr 7:100,239,533...100,565,955
Ensembl chr 7:100,258,441...100,260,795
JBrowse link
G TLR4 toll like receptor 4 severity
susceptibility
no_association
treatment
ISO DNA:polymorphism:cds:p.D299G(human)
DNA:SNP: :rs1927911(human)
protein:decreased expression:nasal mucosa:
DNA:polymorphism: :4216G>C(human)
protein:increased expression:nasal lavage,leukocyte, bone marrow:
RGD PMID:17069098 PMID:19763595 PMID:22402138 PMID:22555057 PMID:22577387 More... RGD:4145354 RGD:7800732 RGD:7800736 RGD:7800738 RGD:7800740 RGD:8552993 NCBI chr12:21,873,762...21,885,562
Ensembl chr12:21,871,773...21,885,515
JBrowse link
Allergic Rhinoconjunctivitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 treatment ISO associated with Eosinophilic Esophagitis; DNA:polymorphisms:: RGD PMID:26416193 RGD:11352743 NCBI chr 9:87,981,300...88,025,007 JBrowse link
G IL3 interleukin 3 susceptibility ISO DNA:SNP: :rs40401(human) RGD PMID:23953855 RGD:13506915 NCBI chr23:34,894,630...34,899,105 JBrowse link
aspirin-induced respiratory disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNG6 calcium voltage-gated channel auxiliary subunit gamma 6 susceptibility ISO DNA:SNP,haplotype:rs192808(human) RGD PMID:20860846 RGD:13524562 NCBI chr 6:46,680,827...46,700,959
Ensembl chr 6:46,682,088...46,700,938
JBrowse link
G CCR3 C-C motif chemokine receptor 3 ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:20022477 PMID:20485159 RGD:4145619 NCBI chr22:7,648,410...7,698,523
Ensembl chr22:7,697,068...7,698,135
JBrowse link
G CYSLTR1 cysteinyl leukotriene receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16502481 PMID:17641958 PMID:20485159
G CYSLTR2 cysteinyl leukotriene receptor 2 ISO DNA:SNPs: :-819T>G, 2078C>T, 2534A>G (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:15970796 PMID:16502481 PMID:20485159 RGD:5144000 NCBI chr 3:26,578,248...26,624,364 JBrowse link
G FANCC FA complementation group C ISO DNA:haplotype::rs4647416(human) RGD PMID:21670957 RGD:11045795 NCBI chr12:107,780,087...107,991,828
Ensembl chr12:107,845,135...107,991,237
JBrowse link
G IL4 interleukin 4 susceptibility ISO DNA:SNPs:promoter,5'UTR,intron:multiple RGD PMID:20921925 RGD:11528633 NCBI chr23:35,492,158...35,501,349
Ensembl chr23:35,492,939...35,501,258
JBrowse link
G LOC103233689 thromboxane A2 receptor susceptibility ISO DNA:polymorphism: :795T>C (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:15898979 PMID:16502481 PMID:20485159 RGD:11059537 NCBI chr 6:3,354,358...3,365,779
Ensembl chr 6:3,355,314...3,359,761
JBrowse link
G LTC4S leukotriene C4 synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:9393345 PMID:9466979 PMID:10970818 PMID:20485159 NCBI chr23:81,523,784...81,526,297
Ensembl chr23:81,523,775...81,526,179
JBrowse link
G MHC-DPB1 major histocompatibility complex, class II, DP beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16502481 NCBI chr17:38,996,329...39,007,097 JBrowse link
G MHC-DQA1 major histocompatibility complex, class II, DQ alpha 1 susceptibility ISO RGD PMID:25975240 RGD:11074090 NCBI chr17:39,422,445...39,428,777
Ensembl chr17:39,420,134...39,428,871
JBrowse link
G MS4A2 membrane spanning 4-domains A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16502481 NCBI chr 1:13,657,842...13,666,314
Ensembl chr 1:13,654,696...13,665,925
JBrowse link
G POSTN periostin ISO CTD Direct Evidence: marker/mechanism CTD PMID:18391768 NCBI chr 3:16,060,013...16,095,867
Ensembl chr 3:16,059,965...16,095,791
JBrowse link
G PTGDR2 prostaglandin D2 receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20485159 NCBI chr 1:12,989,750...12,994,979
Ensembl chr 1:12,992,188...12,993,378
JBrowse link
G PTGER2 prostaglandin E receptor 2 ISO ClinVar Annotator: match by term: Asthma, aspirin-induced, susceptibility to ClinVar PMID:15496426 NCBI chr24:29,395,799...29,410,723
Ensembl chr24:29,396,464...29,409,575
JBrowse link
G PTGIR prostaglandin I2 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20485159 NCBI chr 6:39,977,057...39,983,592
Ensembl chr 6:39,977,864...39,980,860
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO protein:increased expression:mast cell
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:9487340 PMID:16502481 PMID:20485159 RGD:5143936 NCBI chr25:42,733,535...42,742,463
Ensembl chr25:42,734,771...42,742,429
JBrowse link
G TAP2 transporter 2, ATP binding cassette subfamily B member ISO RGD PMID:21796142 RGD:5147839 NCBI chr17:39,266,870...39,277,658 JBrowse link
G TBX21 T-box transcription factor 21 ISO ClinVar Annotator: match by term: Asthma, aspirin-induced, susceptibility to ClinVar PMID:15806396 NCBI chr16:68,131,258...68,145,579
Ensembl chr16:68,131,536...68,144,415
JBrowse link
asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 ISO protein:increased expression:blood, lymphocyte RGD PMID:19484671 RGD:4890020 NCBI chr21:61,211,044...61,430,691
Ensembl chr21:61,322,748...61,529,274
JBrowse link
G ABCC1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) ISO RGD PMID:18931056 RGD:5128825 NCBI chr 5:14,972,589...15,164,594
Ensembl chr 5:14,972,646...15,164,567
JBrowse link
G ABO ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase no_association ISO RGD PMID:16008680 PMID:19771478 RGD:5128831 RGD:5128835 NCBI chr12:4,863,100...4,892,204
Ensembl chr12:4,863,165...4,885,849
JBrowse link
G ACSL3 acyl-CoA synthetase long chain family member 3 ISO DNA:hypermethylation:promoter RGD PMID:19221603 RGD:13831295 NCBI chr10:108,787,341...108,867,523
Ensembl chr10:108,787,061...108,869,042
JBrowse link
G ADA adenosine deaminase susceptibility ISO DNA:polymorphisms (human) RGD PMID:16754522 RGD:5128848 NCBI chr 2:19,167,209...19,200,233 JBrowse link
G ADAM33 ADAM metallopeptidase domain 33 susceptibility
no_association
disease_progression
ISO DNA:SNPs (human)
DNA:SNPs: :multiple (human)
DNA:SNPs:introns,exon:7575G>A, 11188A>T, 12433T>C (human)
DNA:polymorphism: :p.M764T (human)
mRNA:increased expression:bronchus
mRNA:increased expression:lung
RGD PMID:16893396 PMID:17339047 PMID:17961406 PMID:18778489 PMID:19635592 More... RGD:4145359 RGD:4145360 RGD:4145378 RGD:4145379 RGD:4145380 RGD:4145382 NCBI chr 2:34,352,514...34,366,694
Ensembl chr 2:34,353,505...34,366,559
JBrowse link
G ADAM8 ADAM metallopeptidase domain 8 severity ISO mRNA:increased expression:respiratory tract
mRNA:increased expression:bronchus
RGD PMID:17339047 PMID:19373511 PMID:20194813 RGD:4145380 RGD:5128872 RGD:5128878 NCBI chr26:53,114,184...53,129,650
Ensembl chr26:53,114,924...53,126,900
JBrowse link
G ADCY2 adenylate cyclase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chr 4:6,989,077...7,415,282
Ensembl chr 4:6,989,169...7,414,617
JBrowse link
G ADCYAP1R1 ADCYAP receptor type I ISO CTD Direct Evidence: marker/mechanism CTD PMID:21059121 NCBI chr21:27,274,039...27,333,316
Ensembl chr21:27,278,788...27,333,220
JBrowse link
G ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide susceptibility ISO protein:increased expression:respiratory system fluid/secretion
DNA:SNPs: :rs1154404, rs28730619 (human)
RGD PMID:15919956 PMID:17543375 PMID:19395503 PMID:19514054 RGD:5128882 RGD:5128890 RGD:5128891 RGD:5128892 NCBI chr 7:47,190,031...47,211,670
Ensembl chr 7:47,190,294...47,211,651
JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing ISO RGD PMID:19168697 RGD:5686821 NCBI chr15:81,128,427...81,142,779
Ensembl chr15:81,129,795...81,147,391
JBrowse link
G ADORA1 adenosine A1 receptor ISO protein:increased expression:bronchus
DNA:SNPs: :1405C>T (human)
RGD PMID:17959644 PMID:19019667 PMID:20400685 RGD:4145444 RGD:4890386 RGD:5129097 NCBI chr25:26,180,898...26,221,424
Ensembl chr25:26,182,446...26,220,776
JBrowse link
G ADORA2A adenosine A2a receptor ISO DNA:SNP (human)
mRNA:decreased expression:aorta
RGD PMID:16339780 PMID:17293374 PMID:18310516 PMID:19019667 RGD:4890366 RGD:4890380 RGD:4890385 RGD:4890386 NCBI chr19:7,691,678...7,706,781
Ensembl chr19:7,691,536...7,706,926
JBrowse link
G ADRB2 adrenoceptor beta 2 susceptibility ISO ClinVar Annotator: match by term: Beta-2-adrenoreceptor agonist, reduced response to
DNA:SNP: :-1023A>G (human)
ClinVar
RGD
PMID:8383511 PMID:15284533 PMID:16596417 PMID:19638684 RGD:4145081 NCBI chr23:51,445,920...51,447,942
Ensembl chr23:51,446,154...51,447,401
JBrowse link
G AGER advanced glycosylation end-product specific receptor treatment
onset
ISO protein:decreased expression:lung (rat)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:21920897 PMID:23304218 PMID:33075463 RGD:6767554 RGD:7244279 NCBI chr17:39,847,343...39,851,288
Ensembl chr17:39,847,759...39,851,127
JBrowse link
G AGTR1 angiotensin II receptor type 1 ISO RGD PMID:17877756 PMID:19080339 RGD:5147452 RGD:5147457 NCBI chr15:41,957,826...42,002,776 JBrowse link
G AGTR2 angiotensin II receptor type 2 ISO mRNA, protein:increased expression:lung RGD PMID:19080339 RGD:5147457
G ALDH2 aldehyde dehydrogenase 2 family member ISO CTD Direct Evidence: marker/mechanism CTD PMID:9600491 PMID:11506308 NCBI chr11:107,019,015...107,060,784
Ensembl chr11:107,019,111...107,060,374
JBrowse link
G ALOX15 arachidonate 15-lipoxygenase ISO protein:increased expression:lung RGD PMID:18692885 PMID:19628725 RGD:5509605 RGD:5509784 NCBI chr16:4,112,795...4,121,764
Ensembl chr16:4,111,151...4,121,645
JBrowse link
G ALOX5 arachidonate 5-lipoxygenase severity
susceptibility
treatment
no_association
ISO DNA:repeat:promoter (human)
DNA:polymorphism:cds:p.E254K (human)
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:blood, leukocyte
protein:increased expression:lung
DNA:polymorphism:promoter (human)
RGD
CTD
OMIM
PMID:8879219 PMID:9642160 PMID:10369259 PMID:11035107 PMID:12911785 More... RGD:4890407 RGD:4890408 RGD:4890410 RGD:4890413 RGD:4890415 RGD:4890422 RGD:5147462 RGD:5147465 RGD:5147467 RGD:734557 NCBI chr 9:41,085,257...41,145,760
Ensembl chr 9:41,085,361...41,145,331
JBrowse link
G ALOX5AP arachidonate 5-lipoxygenase activating protein no_association
susceptibility
ISO mRNA:increased expression:blood, leukocyte
DNA:polymorphism:promoter (human)
protein:increased expression:lung
DNA:SNP: :rs10507391 (human)
DNA:substitution, repeat:promoter:-336G>A, -169(A)19-23 (human)
DNA:repeat:promoter:-169(A)21 (human)
DNA:polymorphisms:intron:IVS2+12C>A, IVS2+105T>C (human)
DNA:SNPs (human)
RGD PMID:8879219 PMID:9642160 PMID:10527888 PMID:11035107 PMID:12911785 More... RGD:4890405 RGD:4890407 RGD:4890409 RGD:4890422 RGD:5147462 RGD:5147464 RGD:5147465 RGD:5147466 RGD:5147467 NCBI chr 3:9,618,030...9,642,990
Ensembl chr 3:9,617,949...9,643,184
JBrowse link
G AMBP alpha-1-microglobulin/bikunin precursor ISO protein:increased expression:serum RGD PMID:14621078 RGD:6904149 NCBI chr12:25,508,516...25,526,821
Ensembl chr12:25,508,682...25,527,016
JBrowse link
G ANG angiogenin severity ISO protein:increased expression:sputum RGD PMID:16478840 RGD:6892719 NCBI chr29:21,215,985...21,226,927 JBrowse link
G ANXA1 annexin A1 ISO RGD PMID:22092555 RGD:7421657 NCBI chr12:84,207,818...84,226,438
Ensembl chr12:84,207,820...84,226,562
JBrowse link
G AREG amphiregulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:15696081 NCBI chr 7:22,979,574...22,990,179
Ensembl chr 7:22,980,249...22,990,162
JBrowse link
G ARG1 arginase 1 ISO mRNA, protein:increased expression:lung, mononuclear cell (human)
mRNA:increased expression:lung (mouse)
CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs2781667 (human)
RGD
CTD
PMID:12813022 PMID:19281908 PMID:19800904 PMID:20124949 RGD:4143187 RGD:5129205 NCBI chr13:41,971,955...41,983,372
Ensembl chr13:41,971,802...41,983,049
JBrowse link
G ARG2 arginase 2 severity
susceptibility
ISO CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs3742879, rs17249437 (human)
DNA:SNPs (human)
mRNA:increased expression:lung (mouse)
CTD
RGD
PMID:12813022 PMID:16387594 PMID:19281908 PMID:20124949 RGD:4143187 RGD:5129205 RGD:5129207 NCBI chr24:44,851,139...44,884,118
Ensembl chr24:44,851,175...44,883,853
JBrowse link
G BCL2 BCL2 apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:18357729 NCBI chr18:16,440,560...16,643,187
Ensembl chr18:16,441,733...16,637,895
JBrowse link
G BDKRB2 bradykinin receptor B2 onset ISO protein:increased expression:blood, eosinophil
DNA:polymorphism:exon (human)
RGD PMID:8856156 PMID:11517947 PMID:14727005 PMID:19038786 RGD:4890454 RGD:4890456 RGD:4891028 RGD:4891042 NCBI chr24:74,084,907...74,125,604
Ensembl chr24:74,118,210...74,122,909
JBrowse link
G BDNF brain derived neurotrophic factor severity
susceptibility
ISO DNA:polymorphisms: :p.V66M, -270C>T (human)
protein:decreased expression:blood, eosinophil
protein:increased expression:plasma
DNA:polymorphisms: :p.V66M (rs6265) (human)
DNA:SNP,haplotypes: :rs10767664,rs12273539,rs962369(human)
RGD PMID:11737043 PMID:12752594 PMID:17584309 PMID:19895626 PMID:20874832 More... RGD:4891063 RGD:4891067 RGD:4891117 RGD:4891122 RGD:4891123 RGD:8655967 NCBI chr 1:37,386,825...37,451,380
Ensembl chr 1:37,449,593...37,450,336
JBrowse link
G BGLAP bone gamma-carboxyglutamate protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:8429434 NCBI chr20:7,623,716...7,626,353
Ensembl chr20:7,623,883...7,624,812
JBrowse link
G BMPR1B bone morphogenetic protein receptor type 1B ISO protein:decreased expression:bronchus RGD PMID:18292470 RGD:5129470
G BMPR2 bone morphogenetic protein receptor type 2 ISO protein:decreased expression:bronchus RGD PMID:18292470 RGD:5129470 NCBI chr10:88,103,442...88,302,578
Ensembl chr10:88,106,072...88,303,734
JBrowse link
G C3 complement C3 severity ISO DNA:SNP:intron:rs11569562 (human)
protein:increased expression:respiratory system fluid/secretion
DNA:SNPs: :multiple (human)
protein:increased expression:serum
Interaction with IL4RA
DNA:SNP: :4896C>T (human)
RGD PMID:11591733 PMID:15278436 PMID:16355111 PMID:18566738 PMID:20395963 More... RGD:5129501 RGD:5129505 RGD:5129512 RGD:5129517 RGD:5129519 RGD:5129537 RGD:5129538 RGD:5129681 NCBI chr 6:6,250,422...6,289,264 JBrowse link
G C3AR1 complement C3a receptor 1 severity ISO protein:increased expression:lung, leukocyte
mRNA:increased expression:lung
RGD PMID:15278436 PMID:15940127 PMID:17544263 PMID:20045013 PMID:20802484 RGD:5129512 RGD:5129560 RGD:5129561 RGD:5129681 RGD:5129686 NCBI chr11:8,128,192...8,135,517
Ensembl chr11:8,128,620...8,130,062
JBrowse link
G C5 complement C5 severity ISO mRNA:decreased expression:lung RGD PMID:10973279 PMID:11591795 PMID:15278436 PMID:20143644 PMID:20802484 RGD:1600651 RGD:5129512 RGD:5129681 RGD:5129706 RGD:5130158 NCBI chr12:18,525,855...18,624,048
Ensembl chr12:18,525,880...18,623,636
JBrowse link
G C5AR1 complement C5a receptor 1 severity ISO protein:increased expression:lung, leukocyte
protein:increased expression:respiratory tract
RGD PMID:15940127 PMID:16511606 PMID:17544263 PMID:20802484 RGD:5129560 RGD:5129561 RGD:5129681 RGD:5130166 NCBI chr 6:40,633,540...40,651,839
Ensembl chr 6:40,633,448...40,652,845
JBrowse link
G CARD11 caspase recruitment domain family member 11 ISO ClinVar Annotator: match by term: Asthma ClinVar PMID:18323416 PMID:23027925 PMID:23129749 PMID:25352053 PMID:25741868 More...
G CARM1 coactivator associated arginine methyltransferase 1 ISO mRNA:decreased expression:lung RGD PMID:20423833 RGD:9491823 NCBI chr 6:9,866,715...9,915,655
Ensembl chr 6:9,866,534...9,914,682
JBrowse link
G CASP1 caspase 1 ISO protein:increased expression:serum RGD PMID:12396474 RGD:5130192 NCBI chr 1:96,389,697...96,400,610
Ensembl chr 1:96,389,657...96,400,849
JBrowse link
G CAT catalase severity ISO CTD Direct Evidence: marker/mechanism
DNA:polymorphism:promoter:-21A>T (human)
protein:decreased activity:respiratory system fluid/secretion
protein:increased expression:erythrocyte
DNA:polymorphism:promoter:-262C>T (human)
CTD
RGD
PMID:16622028 PMID:18048809 PMID:19373626 PMID:19475625 RGD:5130751 RGD:5130753 RGD:5130856 RGD:5130867 NCBI chr 1:30,792,533...30,828,920
Ensembl chr 1:30,792,399...30,829,592
JBrowse link
G CCL1 C-C motif chemokine ligand 1 ISO protein:increased expression:respiratory system fluid/secretion RGD PMID:20455898 RGD:4891420 NCBI chr16:27,868,925...27,890,143 JBrowse link
G CCL11 C-C motif chemokine ligand 11 treatment
susceptibility
severity
ISO DNA:polymorphism: :p.A23T (human) RGD
OMIM
PMID:17845580 PMID:20704746 PMID:22932891 RGD:4145387 RGD:4145457 RGD:7248416 NCBI chr16:27,792,699...27,796,437
Ensembl chr16:27,794,033...27,796,460
JBrowse link
G CCL17 C-C motif chemokine ligand 17 ISO mRNA:increased expression:lung
protein:increased expression:respiratory system fluid/secretion
RGD PMID:11160256 PMID:15947487 PMID:15993846 PMID:20074456 PMID:20237293 RGD:2306304 RGD:4145486 RGD:4145487 RGD:4145513 RGD:4145603 NCBI chr 5:43,343,525...43,350,096
Ensembl chr 5:43,346,329...43,348,599
JBrowse link
G CCL19 C-C motif chemokine ligand 19 ISO protein:increased expression:bronchus submucosa, mast cell RGD PMID:16959919 RGD:5130911 NCBI chr12:45,928,212...45,930,897
Ensembl chr12:45,929,071...45,930,904
JBrowse link
G CCL2 C-C motif chemokine ligand 2 severity
treatment
ISO CTD Direct Evidence: marker/mechanism
DNA:haplotype::-2518A>G (human)
protein:increased expression:lung
mRNA:increased expression:lung (mouse)
protein:increased expression:serum
CTD
RGD
PMID:12055264 PMID:17964702 PMID:19373627 PMID:20205697 PMID:23454776 More... RGD:11528569 RGD:11528570 RGD:2307055 RGD:4145509 RGD:4891466 RGD:8551842 NCBI chr16:27,763,354...27,765,437
Ensembl chr16:27,763,555...27,765,416
JBrowse link
G CCL20 C-C motif chemokine ligand 20 ISO associated with Allergic Rhinitis;protein:increased expression:serum
protein:increased expression:respiratory system fluid/secretion
RGD PMID:18422729 PMID:22469443 RGD:7483597 RGD:7483618 NCBI chr10:113,815,099...113,836,562
Ensembl chr10:113,832,573...113,835,736
JBrowse link
G CCL22 C-C motif chemokine ligand 22 ISO mRNA, protein:increased expression:respiratory system mucosa, respiratory system fluid/secretion RGD PMID:18684970 RGD:4145489
G CCL24 C-C motif chemokine ligand 24 susceptibility ISO protein:increased expression:plasma
DNA:SNPs: :304C>A, 1272A>G (human)
DNA:SNP: :1265A>G (human)
DNA:SNPs: :179T>C, 275C>T (human)
protein:increased expression:respiratory system fluid/secretion
RGD PMID:12761043 PMID:12952266 PMID:15207712 PMID:16304252 PMID:17060636 More... RGD:4891483 RGD:4891484 RGD:4891485 RGD:4891495 RGD:4891496 RGD:5130930 RGD:5130932 NCBI chr28:10,067,482...10,069,992
Ensembl chr28:10,066,664...10,069,695
JBrowse link
G CCL26 C-C motif chemokine ligand 26 treatment ISO protein:increased expression:plasma
DNA:SNPs: :77C>T, 2497T>G (human)
DNA:SNPs: :77C>T, 716A>G, 1579G>A (human)
RGD PMID:15207712 PMID:16304252 PMID:18712274 PMID:25399816 PMID:25530546 RGD:11081163 RGD:11087575 RGD:4891483 RGD:4891495 RGD:5130930 NCBI chr28:10,036,177...10,038,962
Ensembl chr28:10,036,337...10,038,875
JBrowse link
G CCL27 C-C motif chemokine ligand 27 ISO RGD PMID:19541356 RGD:5130899 NCBI chr12:45,956,596...45,959,354
Ensembl chr12:45,958,642...45,959,313
JBrowse link
G CCL28 C-C motif chemokine ligand 28 ISO mRNA:increased expression:lung (mouse) RGD PMID:16290206 RGD:4892195 NCBI chr 4:42,163,094...42,194,517 JBrowse link
G CCL5 C-C motif chemokine ligand 5 susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:transition:5' utr:-403G>A (human)
protein:increased expression:smooth muscle cell
protein:increased expression:lung, secretion (mouse)
CTD
RGD
PMID:8534483 PMID:18208670 PMID:20092989 PMID:20430255 RGD:2307112 RGD:4891381 RGD:4891430 NCBI chr16:29,351,214...29,361,317 JBrowse link
G CCL7 C-C motif chemokine ligand 7 ISO Promoter polymorphism RGD PMID:19965981 PMID:21388664 RGD:5130979 RGD:5130983 NCBI chr16:27,777,795...27,780,413 JBrowse link
G CCR1 C-C motif chemokine receptor 1 severity ISO mRNA:increased expression:lung
associated with Respiratory Syncytial Virus Infections
RGD PMID:15593301 PMID:15654816 RGD:5688158 RGD:5688159 NCBI chr22:7,634,205...7,641,380 JBrowse link
G CCR2 C-C motif chemokine receptor 2 susceptibility ISO DNA:haplotype:cds:p.V64I(human)
DNA:SNP:cds:p.V64I (human)
protein:increased expression:lung, dendritic cell (mouse)
RGD PMID:17298432 PMID:19917684 PMID:23454776 RGD:4145110 RGD:8549811 RGD:8551842 NCBI chr22:7,795,192...7,801,242
Ensembl chr22:7,798,646...7,799,728
JBrowse link
G CCR3 C-C motif chemokine receptor 3 ISO protein:increased expression:respiratory system fluid/secretion, neutrophil
DNA:SNP:exon:51T>C (human)
RGD PMID:16978084 PMID:17145927 PMID:18699933 PMID:19017998 PMID:19657453 More... RGD:1601020 RGD:4145618 RGD:4145623 RGD:4145632 RGD:4145633 RGD:4145638 RGD:4145646 NCBI chr22:7,648,410...7,698,523
Ensembl chr22:7,697,068...7,698,135
JBrowse link
G CCR4 C-C motif chemokine receptor 4 ISO mRNA:increased expression:lung RGD PMID:15993846 RGD:2306304 NCBI chr15:77,435,195...77,439,164
Ensembl chr15:77,437,265...77,438,347
JBrowse link
G CCR5 C-C motif chemokine receptor 5 no_association ISO mRNA:increased expression:lung (mouse)
DNA:polymorphism, frameshift mutation: :-59029G>A, p.S185_T195del (rs333) (human)
DNA:frameshift mutation:cds:p.S185_T195del rs333 (human)
protein:decreased expression:blood, lymphocyte (human)
RGD PMID:15256090 PMID:16474097 PMID:18094012 PMID:20220260 PMID:23454776 RGD:4145638 RGD:4892088 RGD:4892093 RGD:4892108 RGD:8551842 NCBI chr22:7,803,794...7,818,112 JBrowse link
G CCR6 C-C motif chemokine receptor 6 ISO protein:increased expression:lung, dendritic cell (mouse) RGD PMID:19917684 RGD:8549811 NCBI chr13:94,865,480...94,894,331
Ensembl chr13:94,865,936...94,894,315
JBrowse link
G CCR7 C-C motif chemokine receptor 7 ISO protein:increased expression:lung, dendritic cell (mouse) RGD PMID:19917684 RGD:8549811 NCBI chr16:65,620,632...65,632,394
Ensembl chr16:65,620,665...65,632,984
JBrowse link
G CCR8 C-C motif chemokine receptor 8 ISO mRNA:increased expression:lung RGD PMID:15993846 RGD:2306304 NCBI chr15:83,215...87,282
Ensembl chr15:83,495...84,562
JBrowse link
G CCR9 C-C motif chemokine receptor 9 ISO mRNA, protein:increased expression:blood, mature NK T cell RGD PMID:16210593 RGD:5130925 NCBI chr22:7,354,139...7,375,280
Ensembl chr22:7,354,489...7,377,676
JBrowse link
G CD14 CD14 molecule no_association
severity
susceptibility
ISO protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:promoter:c. -159C>T (human)
DNA:polymorphism:promoter:c. -260C>T (human)
DNA:SNPs: :
protein:increased expression:serum|DNA:polymorphism:promoter:c. -159C>T (human)
RGD
CTD
PMID:15741437 PMID:15940135 PMID:16387800 PMID:17607003 PMID:18312481 More... RGD:4144208 RGD:4144228 RGD:4144813 RGD:4144814 RGD:4144815 NCBI chr23:43,264,917...43,266,825
Ensembl chr23:43,264,336...43,266,993
JBrowse link
G CD1D CD1d molecule susceptibility ISO associated with fasciolopsiasis RGD PMID:20304473 RGD:4140417 NCBI chr20:5,726,307...5,733,355
Ensembl chr20:5,727,049...5,730,061
JBrowse link
G CD209 CD209 molecule ISO RGD PMID:21471959 RGD:5131188 NCBI chr 6:7,219,576...7,235,755
Ensembl chr 6:7,228,378...7,235,208
JBrowse link
G CD274 CD274 molecule treatment ISO associated with Chlamydia pneumonia RGD PMID:26378990 RGD:41412180 NCBI chr12:74,038,844...74,060,662
Ensembl chr12:74,041,767...74,056,806
JBrowse link
G CD28 CD28 molecule ISO RGD PMID:21356099 RGD:5131612 NCBI chr10:89,471,710...89,505,152
Ensembl chr10:89,471,730...89,500,387
JBrowse link
G CD40 CD40 molecule treatment ISO RGD PMID:19159017 PMID:19220210 PMID:20205594 PMID:20941750 RGD:4144188 RGD:4892277 RGD:5132272 RGD:8547792 NCBI chr 2:17,753,713...17,765,134
Ensembl chr 2:17,753,394...17,764,566
JBrowse link
G CD40LG CD40 ligand severity ISO RGD PMID:9502776 RGD:11352238 NCBI chr  X:111,655,301...111,667,602
Ensembl chr  X:111,655,397...111,666,639
JBrowse link
G CD80 CD80 molecule ISO RGD PMID:21051864 PMID:21352203 PMID:21440530 RGD:5132619 RGD:5132620 RGD:5132621 NCBI chr22:61,258,281...61,294,772 JBrowse link
G CD86 CD86 molecule treatment ISO DNA:snp:exon:p.I179V rs2681417 (human)
protein:increased expression:blood, B cell (human)
protein:increased expression:lung, alveolar macrophage (mouse)
protein:increased expression:lung, dendritic cell (rat)
RGD PMID:9449507 PMID:9551945 PMID:17513529 PMID:20668438 PMID:20941750 More... RGD:11354965 RGD:4892199 RGD:4892202 RGD:4892277 RGD:4892280 RGD:4892555 NCBI chr22:58,741,534...58,805,417
Ensembl chr22:58,741,525...58,805,366
JBrowse link
G CDHR3 cadherin related family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24241537 NCBI chr21:74,875,272...74,947,964 JBrowse link
G CFTR CF transmembrane conductance regulator susceptibility ISO DNA:deletion: :p.F508del(human) RGD PMID:20298391 RGD:4140387 NCBI chr21:86,154,313...86,332,436 JBrowse link
G CHAT choline O-acetyltransferase ISO Protein:decreased expression:lung epithelium RGD PMID:17328924 RGD:5686690 NCBI chr 9:42,159,367...42,216,137
Ensembl chr 9:42,162,601...42,214,705
JBrowse link
G CHI3L1 chitinase 3 like 1 susceptibility ISO ClinVar Annotator: match by term: Asthma-related traits, susceptibility to, 7 OMIM
ClinVar
PMID:18403759 NCBI chr25:26,160,993...26,169,005
Ensembl chr25:26,160,961...26,169,566
JBrowse link
G CHML CHM like Rab escort protein ISO RGD PMID:18343558 RGD:5133238 NCBI chr25:78,712,003...78,714,842 JBrowse link
G CHRM1 cholinergic receptor muscarinic 1 ISO RGD PMID:16931638 RGD:5133416 NCBI chr 1:10,978,464...10,991,650
Ensembl chr 1:10,989,207...10,990,589
JBrowse link
G CHRM2 cholinergic receptor muscarinic 2 ISO DNA:SNP: :rs6962027 (human) RGD PMID:19308904 RGD:5509586 NCBI chr21:105,574,879...105,730,265
Ensembl chr21:105,726,175...105,727,575
JBrowse link
G CHRM3 cholinergic receptor muscarinic 3 severity ISO RGD PMID:18348887 PMID:20394512 RGD:5133437 RGD:5133438 NCBI chr25:76,772,212...77,009,433
Ensembl chr25:77,001,477...77,003,249
JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex ISO RGD PMID:21496385 RGD:5133703 NCBI chr 9:93,219,374...93,263,077
Ensembl chr 9:93,219,383...93,262,700
JBrowse link
G CLCA1 chloride channel accessory 1 susceptibility ISO DNA:SNPs (human) RGD PMID:11296262 PMID:15318163 PMID:17898169 RGD:4145653 RGD:4145656 RGD:4145661 NCBI chr20:46,930,713...46,964,301
Ensembl chr20:46,927,412...46,963,737
JBrowse link
G CLDN18 claudin 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27215490 NCBI chr15:52,509,568...52,533,205
Ensembl chr15:52,508,887...52,532,836
JBrowse link
G CMA1 chymase 1 no_association
susceptibility
severity
ISO DNA:polymorphism:5' utr:g.-1903G>A rs1800875 (human)
DNA:duplications:3' utr:g.*254-?dupTG, dupGA (human)
protein:increased expression:lung epithelium, mast cell (human)
RGD PMID:15248847 PMID:15924217 PMID:20813890 RGD:1625396 RGD:1625397 RGD:5128804 NCBI chr24:1,471,767...1,475,062
Ensembl chr24:1,471,725...1,474,692
JBrowse link
G CRHR2 corticotropin releasing hormone receptor 2 ISO DNA:SNPs: :multiple (human) RGD PMID:18408560 RGD:5130938 NCBI chr21:27,703,637...27,738,873
Ensembl chr21:27,708,113...27,739,116
JBrowse link
G CRP C-reactive protein ISO protein:increased expression:serum RGD PMID:21140796 RGD:5131288 NCBI chr20:4,232,262...4,235,826
Ensembl chr20:4,232,913...4,235,377
JBrowse link
G CSF2 colony stimulating factor 2 severity ISO protein:increased expression:sputum
protein:increased expression:lung
RGD PMID:9717963 PMID:19213775 PMID:20405019 RGD:10449521 RGD:5131473 RGD:5131476 NCBI chr23:34,906,987...34,911,252
Ensembl chr23:34,908,911...34,911,140
JBrowse link
G CSF2RB colony stimulating factor 2 receptor subunit beta ISO RGD PMID:17145927 RGD:1601020 NCBI chr19:19,614,719...19,642,546
Ensembl chr19:19,624,234...19,640,617
JBrowse link
G CSF3 colony stimulating factor 3 ISO protein:increased expression:lung RGD PMID:20405019 PMID:21396376 RGD:5131473 RGD:5133731 NCBI chr16:66,162,814...66,166,192
Ensembl chr16:66,163,681...66,165,172
JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 severity
treatment
no_association
ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:serum
DNA:polymorphisms:promoter, exon:-318C>T 49A>G (human)
DNA:SNPs: :multiple (human)
DNA:polymorphism:promoter:-318C>T (human)
DNA:SNPs:promoter, exon:-1147C>T, -318C>T, 49A>G (human)
DNA:SNP: :rs3087243 (human)
CTD
RGD
PMID:11726402 PMID:12114354 PMID:12956753 PMID:15316504 PMID:15871446 More... RGD:11344922 RGD:4891510 RGD:4891514 RGD:4891516 RGD:4891517 RGD:4891519 RGD:4891521 RGD:4891522 RGD:4891526 RGD:4891527 RGD:4891528 RGD:4891529 NCBI chr10:89,637,176...89,644,436
Ensembl chr10:89,638,314...89,642,344
JBrowse link
G CTNNA3 catenin alpha 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19187332 NCBI chr 9:63,669,561...65,406,737 JBrowse link
G CX3CR1 C-X3-C motif chemokine receptor 1 no_association ISO DNA:SNPs: :p.V249I, rs2669849 (human)
DNA:polymorphisms: :p.V249I, p.T280M (human)
RGD PMID:17082760 PMID:17505143 PMID:21037587 RGD:4891882 RGD:4891895 RGD:4891904 NCBI chr15:136,757...153,316
Ensembl chr15:150,718...151,785
JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 severity ISO RGD PMID:20371397 RGD:5134983 NCBI chr 7:22,327,041...22,329,405
Ensembl chr 7:22,569,355...22,569,900
Ensembl chr 7:22,569,355...22,569,900
JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 ISO protein:decreased expression:plasma RGD PMID:11994485 PMID:16602032 PMID:17302903 RGD:5135439 RGD:5135452 RGD:5135457 NCBI chr 7:24,526,657...24,529,193
Ensembl chr 7:24,526,680...24,529,130
JBrowse link
G CXCL14 C-X-C motif chemokine ligand 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21150878 NCBI chr23:38,355,340...38,363,905
Ensembl chr23:38,355,341...38,363,680
JBrowse link
G CXCL6 C-X-C motif chemokine ligand 6 ISO RGD PMID:9620668 RGD:5135265 NCBI chr 7:22,291,949...22,294,191
Ensembl chr 7:22,292,045...22,294,207
JBrowse link
G CXCL9 C-X-C motif chemokine ligand 9 ISO RGD PMID:15210824 RGD:5135447 NCBI chr 7:24,507,121...24,513,830
Ensembl chr 7:24,507,130...24,513,121
JBrowse link
G CXCR3 C-X-C motif chemokine receptor 3 severity
susceptibility
ISO protein:decreased expression:respiratory system fluid/secretion, T cell
DNA:SNP:intron:IVS1+234G>A (human)
RGD PMID:16043121 PMID:16548899 PMID:17641057 PMID:18094012 RGD:4892088 RGD:5135484 RGD:5143932 RGD:5143934 NCBI chr  X:61,430,723...61,433,777
Ensembl chr  X:61,430,725...61,433,386
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO mRNA, protein:increased expression, decreased activity:lung RGD PMID:12415424 RGD:4892074 NCBI chr26:8,753,236...8,759,378
Ensembl chr26:8,753,327...8,759,384
JBrowse link
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 ISO DNA:polymorphism: :1934G>A (human) RGD PMID:19575027 RGD:5143944 NCBI chr19:24,667,207...24,672,580
Ensembl chr19:24,667,282...24,671,513
JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:leukocyte
CTD
RGD
PMID:17081494 PMID:20514434 PMID:28807506 RGD:4892076 RGD:4892220 NCBI chr26:53,390,054...53,403,309
Ensembl chr26:53,390,089...53,404,211
JBrowse link
G CYSLTR1 cysteinyl leukotriene receptor 1 no_association
severity
ISO DNA:SNPs:promoter:-634C>T, -475A>C, -336A>G (human)
DNA:SNPs:promoter, exon:multiple (human)
mRNA, protein:increased expression:respiratory system mucosa
DNA:SNP: :927T>C (human)
RGD PMID:8087328 PMID:11591188 PMID:16123393 PMID:16630147 PMID:16771777 More... RGD:4781742 RGD:4782072 RGD:4784257 RGD:4847129 RGD:4848936 RGD:4888514 RGD:4889116
G CYSLTR2 cysteinyl leukotriene receptor 2 ISO DNA:polymorphism: :601A>G (human)
DNA:polymorphism: :-1220A>C (human)
RGD PMID:15454733 PMID:15475736 RGD:5144002 RGD:5144003 NCBI chr 3:26,578,248...26,624,364 JBrowse link
G DCN decorin ISO RGD PMID:16387756 RGD:2311423 NCBI chr11:86,552,392...86,590,229
Ensembl chr11:86,551,072...86,586,891
JBrowse link
G DEFB1 defensin beta 1 susceptibility ISO DNA:SNP: :-1816 T>C (human)
DNA:SNPs:5' utr:g.-52G>A, g.-44C>G, g.-20G>A (human)
RGD PMID:15696078 PMID:16435024 RGD:4892254 RGD:4892263 NCBI chr 8:6,643,753...6,652,209
Ensembl chr 8:6,643,556...6,651,699
JBrowse link
G DNAH5 dynein axonemal heavy chain 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chr 4:13,401,980...13,718,900
Ensembl chr 4:13,401,092...13,652,755
JBrowse link
G DNMT1 DNA methyltransferase 1 ISO CTD Direct Evidence: marker/mechanism
DNA,mRNA:hypermethylation,decreased expression:promoter,respiratory tract:
CTD
RGD
PMID:23196709 PMID:23423710 RGD:9588646 NCBI chr 6:9,199,006...9,263,890
Ensembl chr 6:9,199,003...9,263,607
JBrowse link
G DPP10 dipeptidyl peptidase like 10 ISO DNA:SNPs (human)
DNA:SNP:exon (human)
DNA:SNP: :rs10208402 (human)
protein:increased expression:bronchus
RGD PMID:14566338 PMID:17967935 PMID:19672052 PMID:21103062 RGD:4889866 RGD:4892275 RGD:4892276 RGD:4892278 NCBI chr10:14,434,244...15,822,419 JBrowse link
G EBI3 Epstein-Barr virus induced 3 ISO RGD PMID:21255010 RGD:5128488 NCBI chr 6:3,975,805...3,985,389
Ensembl chr 6:3,976,228...3,984,962
JBrowse link
G EDN1 endothelin 1 ISO CTD Direct Evidence: marker/mechanism
DNA:transition:intron:g.4124T>C (human)
Severe Persistent Allergic Asthma; protein:increased secretion:lung (human)
CTD
RGD
PMID:11668616 PMID:16981460 PMID:20588001 RGD:4144869 RGD:4144895 NCBI chr17:59,854,186...59,861,319
Ensembl chr17:59,853,699...59,861,198
JBrowse link
G EDNRA endothelin receptor type A ISO RGD PMID:17448648 PMID:18632188 RGD:4892288 RGD:4892322 NCBI chr 7:93,980,983...94,043,863
Ensembl chr 7:93,985,797...94,042,296
JBrowse link
G EDNRB endothelin receptor type B ISO DNA:polymorphism (human)
mRNA:increased expression:bronchus, smooth muscle cell
RGD PMID:15245576 PMID:17470272 PMID:18632188 RGD:4892288 RGD:4892321 RGD:4892324 NCBI chr 3:56,969,493...56,993,719
Ensembl chr 3:56,969,101...56,992,731
JBrowse link
G EGFR epidermal growth factor receptor severity ISO protein:increased expression:lung epithelium (rat)
protein:increased expression:lung epithelium (mouse)
protein:increased expression:bronchial epithelium (human)
RGD PMID:12580917 PMID:19954006 PMID:21072743 PMID:21224214 RGD:5131468 RGD:5131633 RGD:5131642 RGD:5131870 NCBI chr21:3,664,622...3,853,492
Ensembl chr21:3,666,339...3,853,239
JBrowse link
G EGR1 early growth response 1 ISO DNA:snp:5' utr:g.-4071A>G rs7729723 (human)
mRNA:increased expression:bronchoalveolar lavage cell (human)
RGD PMID:11254538 PMID:18507785 PMID:18774390 RGD:5130915 RGD:5131985 RGD:5131993 NCBI chr23:41,139,636...41,143,598
Ensembl chr23:41,140,065...41,142,374
JBrowse link
G ELP1 elongator acetyltransferase complex subunit 1 no_association ISO RGD PMID:11281413 PMID:12774215 RGD:5129157 RGD:5129158 NCBI chr12:30,620,685...30,687,583
Ensembl chr12:30,620,278...30,687,405
JBrowse link
G EPHX1 epoxide hydrolase 1 susceptibility ISO DNA:SNPs:exons:p.Y113H (rs1051740), p.H139R (rs2234922) (human) RGD PMID:17711870 RGD:4889407 NCBI chr25:3,924,396...3,960,264
Ensembl chr25:3,924,606...3,945,535
JBrowse link
G EPX eosinophil peroxidase disease_progression
severity
ISO protein:increased activity:sputum,nasal,pharyngeal mucosa RGD PMID:12199967 PMID:20813885 PMID:26645423 RGD:11574908 RGD:13506891 RGD:13506892 NCBI chr16:35,196,433...35,208,269
Ensembl chr16:35,192,971...35,207,874
JBrowse link
G ESR2 estrogen receptor 2 ISO mRNA:decreased expression:lung (rat) RGD PMID:18375789 RGD:8694127 NCBI chr24:41,426,333...41,513,802
Ensembl chr24:41,447,224...41,512,486
JBrowse link
G F2RL1 F2R like trypsin receptor 1 ISO RGD PMID:19864598 RGD:4892589 NCBI chr 4:71,095,446...71,109,832
Ensembl chr 4:71,095,500...71,110,005
JBrowse link
G F7 coagulation factor VII treatment ISO RGD PMID:24523826 RGD:11040539 NCBI chr 3:91,109,864...91,122,707
Ensembl chr 3:91,110,380...91,123,327
JBrowse link
G FCER1A Fc fragment of IgE receptor Ia severity ISO Asthma symptoms persistent despite steroids
Fatal asthma subjects
RGD PMID:20937062 PMID:21388666 RGD:5128711 RGD:5128717 NCBI chr20:4,635,316...4,640,787
Ensembl chr20:4,635,328...4,640,590
JBrowse link
G FCGR2A Fc fragment of IgG receptor IIa ISO protein:increased expression:alveolar macrophage RGD PMID:9117017 RGD:5147982 NCBI chr20:2,480,710...2,512,429 JBrowse link
G FCGR3A Fc fragment of IgG receptor IIIa susceptibility ISO DNA:polymorphism:exon:p.F158V(rs396991)(human) RGD PMID:18199088 RGD:5508449 NCBI chr20:2,466,492...2,475,579 JBrowse link
G FGA fibrinogen alpha chain treatment ISO RGD PMID:24523826 RGD:11040539 NCBI chr 7:101,127,554...101,134,881
Ensembl chr 7:101,125,791...101,134,405
JBrowse link
G FKBP5 FKBP prolyl isomerase 5 ISO ClinVar Annotator: match by term: Asthma ClinVar NCBI chr17:36,432,595...36,551,233
Ensembl chr17:36,481,024...36,552,456
JBrowse link
G FOXP3 forkhead box P3 treatment ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:27633092 PMID:27965764 PMID:28944907 PMID:29317916 RGD:38548920 RGD:38549365 NCBI chr  X:46,349,890...46,365,133 JBrowse link
G GATA3 GATA binding protein 3 ISO RGD PMID:9949310 PMID:18186587 RGD:5128802 RGD:5128803 NCBI chr 9:8,101,404...8,122,762
Ensembl chr 9:8,101,432...8,123,064
JBrowse link
G GC GC vitamin D binding protein ISO protein, mRNA:increased expression:bronchoalveolar lavage fluid: RGD PMID:21169467 RGD:5509920 NCBI chr 7:20,254,604...20,298,384
Ensembl chr 7:20,253,879...20,298,265
JBrowse link
G GSDMB gasdermin B ISO CTD Direct Evidence: marker/mechanism CTD PMID:24241537 NCBI chr16:66,253,562...66,266,391 JBrowse link
G GSTM3 glutathione S-transferase mu 3 ISO DNA:polymorphism RGD PMID:11470996 PMID:17550934 RGD:5135038 RGD:5135039 NCBI chr20:23,797,794...23,802,910
Ensembl chr20:23,799,177...23,802,921
JBrowse link
G GSTO2 glutathione S-transferase omega 2 susceptibility ISO DNA:polymorphism:exon:p. N142D (human) RGD PMID:20374258 RGD:5490988 NCBI chr 9:97,319,695...97,348,406
Ensembl chr 9:97,325,215...97,349,422
JBrowse link
G GSTP1 glutathione S-transferase pi 1 no_association
severity
susceptibility
disease_progression
ISO DNA:SNPs: :p.I105V, p.A114V (human)
CTD Direct Evidence: marker/mechanism
DNA:SNPs:exons:p.I105V (rs1695), A114V (rs1138272) (human)
DNA:polymorphism:exon:p.I105V (rs1695) (human)
DNA:SNPs:intron,exon:(rs749174), (rs1138272)(human)
DNA:polymorphism:exon:p.I105V (human)
DNA:SNP: :p.A114V (human)
RGD
CTD
PMID:10806136 PMID:11994713 PMID:15693909 PMID:16176403 PMID:16870661 More... RGD:4140946 RGD:4140947 RGD:4140951 RGD:4142519 RGD:4142526 RGD:5490985 RGD:5490991 RGD:5490999 NCBI chr 1:6,676,897...6,679,936 JBrowse link
G HAVCR1 hepatitis A virus cellular receptor 1 ISO RGD PMID:20628202 RGD:5128851 NCBI chr23:59,422,769...59,454,183
Ensembl chr23:59,423,334...59,453,531
JBrowse link
G HAVCR2 hepatitis A virus cellular receptor 2 ISO RGD PMID:17517968 RGD:5135525 NCBI chr23:59,479,794...59,501,532
Ensembl chr23:59,475,826...59,500,836
JBrowse link
G HDAC2 histone deacetylase 2 ISO mRNA:decreased expression:macrophage: RGD PMID:20538962 RGD:9590321 NCBI chr13:59,873,248...59,904,542
Ensembl chr13:59,873,767...59,905,742
JBrowse link
G HDC histidine decarboxylase ISO associated with Rhinitis;DNA:SNP: :p.E644D (rs2073440) (human) RGD PMID:20608921 RGD:5128884 NCBI chr26:33,051,048...33,074,872
Ensembl chr26:33,051,966...33,074,563
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha treatment ISO RGD PMID:18160846 RGD:10402541 NCBI chr24:38,873,830...38,927,657
Ensembl chr24:38,873,861...38,928,288
JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:20084838 RGD:5508450 NCBI chr 4:69,664,784...69,690,343
Ensembl chr 4:69,665,417...69,688,686
JBrowse link
G HMOX1 heme oxygenase 1 severity ISO mRNA;protein:increased expression:Leukocytes, Mononuclear
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:16196283 PMID:18048809 PMID:20596599 RGD:4145403 RGD:4145408 NCBI chr19:18,144,466...18,157,944
Ensembl chr19:18,144,545...18,157,971
JBrowse link
G HNMT histamine N-methyltransferase no_association ISO ClinVar Annotator: match by term: Asthma, susceptibility to RGD
OMIM
ClinVar
PMID:10752634 PMID:10803682 PMID:15693910 PMID:16205835 PMID:17651147 More... RGD:5128885 RGD:5128887 RGD:5128888 NCBI chr10:22,188,151...22,238,665
Ensembl chr10:22,188,110...22,238,671
JBrowse link
G HSD11B2 hydroxysteroid 11-beta dehydrogenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11932298 NCBI chr 5:60,017,967...60,040,959
Ensembl chr 5:60,019,434...60,025,353
JBrowse link
G HTR2A 5-hydroxytryptamine receptor 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:25322896 NCBI chr 3:24,820,029...24,884,472
Ensembl chr 3:24,820,035...24,883,432
JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO mRNA:increased expression:aorta (mouse)
CTD Direct Evidence: marker/mechanism
protein:increased secretion:lung (human)
protein:increased expression:lung, serum (rat)
RGD
CTD
PMID:17014439 PMID:20205697 PMID:20400685 PMID:20953388 PMID:25003170 RGD:4145331 RGD:4145444 RGD:4145509 NCBI chr 6:9,320,991...9,338,125
Ensembl chr 6:9,322,550...9,338,263
JBrowse link
G IFNG interferon gamma resistance
treatment
ISO protein:increased expression:sputum RGD PMID:12396623 PMID:19542437 PMID:20817868 PMID:20953328 RGD:10755706 RGD:4145525 RGD:4145651 RGD:5128479 NCBI chr11:63,785,493...63,791,071
Ensembl chr11:63,786,041...63,790,473
JBrowse link
G IFNGR1 interferon gamma receptor 1 ISO DNA: SNP: Leu467Pro RGD PMID:12851715 PMID:21737883 RGD:6480255 RGD:6480431 NCBI chr13:36,203,038...36,224,039
Ensembl chr13:36,203,004...36,222,542
JBrowse link
G IFNL3 interferon lambda 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22295096 NCBI chr 6:33,843,140...33,845,444 JBrowse link
G IKZF3 IKAROS family zinc finger 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25256354 NCBI chr16:66,302,107...66,399,152
Ensembl chr16:66,303,117...66,397,765
JBrowse link
G IL10 interleukin 10 susceptibility
treatment
ISO protein:decreased expression:plasma
DNA:polymorphism: :-627C>A (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:12938145 PMID:20121766 PMID:20230687 PMID:20237464 PMID:20560982 More... RGD:11046261 RGD:4140421 RGD:4140451 RGD:4140459 RGD:4140471 RGD:4143221 RGD:5131623 NCBI chr25:22,590,389...22,595,877
Ensembl chr25:22,590,962...22,594,836
JBrowse link
G IL12A interleukin 12A ISO RGD PMID:17056578 PMID:17548618 RGD:4373570 RGD:4438438 NCBI chr15:30,887,048...30,896,577
Ensembl chr15:30,887,897...30,894,550
JBrowse link
G IL12B interleukin 12B susceptibility
severity
ISO DNA:polymorphisms:promoter, 3'utr:
ClinVar Annotator: match by term: Asthma, susceptibility to
DNA:polymorphism:promoter
DNA:polymorphisms:introns:
RGD
ClinVar
PMID:12241719 PMID:15322986 PMID:16210052 RGD:1600043 RGD:4145428 RGD:4145438 NCBI chr23:61,714,293...61,731,835 JBrowse link
G IL13 interleukin 13 susceptibility
severity
no_association
ISO ClinVar Annotator: match by term: Asthma, susceptibility to
protein:increased expression:serum
DNA:polymorphism: :c.-1055C>T (human)
DNA:polymorphism:cds:p.R130Q (human)
protein:increased expression:sputum
OMIM
ClinVar
RGD
PMID:10699178 PMID:11588017 PMID:11678850 PMID:11709756 PMID:11758895 More... RGD:4145593 RGD:4145639 RGD:4145777 RGD:4763153 RGD:4763761 NCBI chr23:35,475,762...35,479,419
Ensembl chr23:35,476,490...35,478,869
JBrowse link
G IL13RA1 interleukin 13 receptor subunit alpha 1 no_association ISO DNA:polymorphism: :1050C>T (human)
DNA:polymorphism: :1398A>G (human)
DNA:polymorphisms:promoter, 3' utr:-281T>G, 1365A>G (human)
mRNA:increased expression:bronchus
RGD PMID:10686479 PMID:11714828 PMID:17006604 PMID:17392323 PMID:18480254 More... RGD:4892639 RGD:4892646 RGD:4892647 RGD:4892650 RGD:4892654 RGD:4892655
G IL13RA2 interleukin 13 receptor subunit alpha 2 ISO mRNA:increased expression:bronchus
protein:increased expression:serum
RGD PMID:17885690 PMID:20383033 PMID:21462799 RGD:4892646 RGD:4892649 RGD:8549521 NCBI chr  X:102,589,947...102,628,853
Ensembl chr  X:102,590,045...102,603,260
JBrowse link
G IL15 interleukin 15 no_association ISO DNA:SNPs: :multiple (human) RGD PMID:11160248 PMID:15131572 PMID:15843549 PMID:16629787 PMID:19133918 RGD:4984421 RGD:4990462 RGD:5000757 RGD:5000758 RGD:5000760 NCBI chr 7:88,548,773...88,644,977
Ensembl chr 7:88,548,671...88,645,488
JBrowse link
G IL16 interleukin 16 severity
no_association
ISO associated with Rhinitis;protein:increased expression:respiratory system fluid/secretion
DNA:SNP:promoter:-295T>C (human)
protein:increased expression:serum
RGD PMID:10585533 PMID:12872394 PMID:15784111 PMID:16387589 PMID:16734115 RGD:5024928 RGD:5024930 RGD:5024934 RGD:5024935 RGD:5024937 NCBI chr26:2,080,985...2,208,764
Ensembl chr26:2,077,228...2,208,431
JBrowse link
G IL17A interleukin 17A susceptibility ISO DNA:SNP:promoter:rs2275913 (human)
protein:increased expression:alveolar macrophage
protein:increased expression:sputum
mRNA,protein:increased expression:Leukocytes, Mononuclear, lung, serum
RGD PMID:15730730 PMID:18060619 PMID:18941201 PMID:20351038 PMID:20437253 RGD:4839043 RGD:4888527 RGD:4889114 RGD:4889139 RGD:4889152 NCBI chr17:20,314,082...20,319,917
Ensembl chr17:20,315,773...20,318,785
JBrowse link
G IL17RB interleukin 17 receptor B ISO associated with Picornaviridae Infections RGD PMID:25273095 RGD:39128256 NCBI chr22:15,229,020...15,249,145
Ensembl chr22:15,229,053...15,248,437
JBrowse link
G IL18 interleukin 18 susceptibility
severity
disease_progression
ISO DNA:SNP:promoter:c.and -137G>C (rs187238)(human)
DNA:SNPs:Promoter:c. -607C>A (rs1946518), -137G/C (rs187238) (human)
protein:increased expression:serum
DNA:SNP:promoter: c.-380C>G (rs5744247)(human)
DNA:polymorphism: :c. -105A>C (human)
RGD PMID:11174201 PMID:16433859 PMID:17767553 PMID:18200581 PMID:18826499 More... RGD:4889585 RGD:4889863 RGD:4889898 RGD:4889900 RGD:4889908 RGD:4889910 RGD:4889923 NCBI chr 1:103,485,868...103,511,632
Ensembl chr 1:103,482,083...103,510,150
JBrowse link
G IL18R1 interleukin 18 receptor 1 ISO DNA:SNPs: :multiple (human)
DNA:SNP: :rs3771166 (human)
RGD PMID:11972614 PMID:18382474 PMID:18774397 PMID:19910030 PMID:20860503 RGD:5024942 RGD:5024945 RGD:5024946 RGD:5024947 RGD:5024948 NCBI chr14:6,026,683...6,067,808
Ensembl chr14:6,026,443...6,066,884
JBrowse link
G IL19 interleukin 19 ISO mRNA, protein:increased expression:lung, serum
protein:increased expression:serum
RGD PMID:15557163 RGD:5037236 NCBI chr25:22,514,199...22,523,680
Ensembl chr25:22,514,559...22,520,499
JBrowse link
G IL1A interleukin 1 alpha ISO DNA:polymorphisms: : RGD PMID:18763028 RGD:4142802 NCBI chr14:15,789,710...15,801,938
Ensembl chr14:15,789,013...15,796,611
JBrowse link
G IL1B interleukin 1 beta susceptibility ISO protein:decreased expression:neutrophil
DNA:polymorphism: :-511C>T (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:9176529 PMID:18926055 PMID:19684087 PMID:19842845 RGD:4142830 RGD:4142836 RGD:4142864 NCBI chr14:15,844,628...15,852,652
Ensembl chr14:15,844,672...15,850,729
JBrowse link
G IL1RL1 interleukin 1 receptor like 1 susceptibility
severity
ISO CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs1041973 (human)
DNA:SNP: :rs1420101 (human)
DNA:SNP: :rs10197862 (human)
protein:increased expression:serum
DNA:SNPs:intron:rs1420089, rs1861245,rs1946131 (human)
CTD
RGD
PMID:11463601 PMID:17407196 PMID:17623648 PMID:19179489 PMID:19198610 More... RGD:5144235 RGD:5144237 RGD:5144239 RGD:5144240 RGD:5144242 RGD:5144243 RGD:5144244 RGD:5144245 NCBI chr14:5,966,551...6,020,391
Ensembl chr14:6,005,061...6,020,265
JBrowse link
G IL1RN interleukin 1 receptor antagonist susceptibility
severity
ISO DNA:polymorphism:intron (human)
DNA:SNPs: :rs447713, rs3087271 (human)
protein:increased expression:plasma
DNA, protein:repeat, decreased expression (human)
CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs2234678 (human)
DNA:SNPs: :multiple (human)
RGD
CTD
PMID:9176529 PMID:10843772 PMID:11027520 PMID:15020290 PMID:16409203 More... RGD:4142802 RGD:4142864 RGD:4143163 RGD:4143208 RGD:4143209 RGD:4143216 RGD:4143224 RGD:4143225 NCBI chr14:16,136,667...16,152,451
Ensembl chr14:16,146,333...16,151,326
JBrowse link
G IL2 interleukin 2 susceptibility ISO DNA:SNP:promoter:rs2069762(human) RGD PMID:16333313 PMID:20926789 RGD:4889118 RGD:8663473 NCBI chr 7:69,729,635...69,736,279
Ensembl chr 7:69,730,282...69,734,969
JBrowse link
G IL21 interleukin 21 ISO DNA:SNP:exon:5250C>T (human) RGD PMID:18802358 RGD:5147396 NCBI chr 7:69,859,793...69,872,237
Ensembl chr 7:69,863,535...69,872,025
JBrowse link
G IL22 interleukin 22 treatment
severity
ISO mRNA:increased expression:blood, mononuclear cell
protein:increased expression:serum
RGD PMID:21297073 PMID:21535180 PMID:21998459 RGD:11046261 RGD:5147403 RGD:5147409 NCBI chr11:63,881,743...63,887,695
Ensembl chr11:63,882,093...63,886,761
JBrowse link
G IL23R interleukin 23 receptor ISO RGD PMID:19935773 RGD:5037240 NCBI chr20:65,853,379...65,946,000
Ensembl chr20:65,854,349...65,938,024
JBrowse link
G IL25 interleukin 25 ISO mRNA, protein:increased expression:lung RGD PMID:25273095 RGD:39128256 NCBI chr29:23,742,377...23,747,902
Ensembl chr29:23,744,449...23,747,176
JBrowse link
G IL27 interleukin 27 treatment
susceptibility
ISO DNA:SNP: :g.-964A>G (human)
protein:increased expression:sputum
RGD PMID:17318299 PMID:17878337 PMID:19542437 PMID:20817868 PMID:26595888 RGD:11076728 RGD:4145651 RGD:5128479 RGD:5128485 RGD:5128491 NCBI chr 5:26,348,559...26,358,028
Ensembl chr 5:26,348,848...26,356,360
JBrowse link
G IL27RA interleukin 27 receptor subunit alpha ISO RGD PMID:16081811 RGD:5128496 NCBI chr 6:12,679,270...12,699,254
Ensembl chr 6:12,686,838...12,701,867
JBrowse link
G IL2RA interleukin 2 receptor subunit alpha ISO RGD PMID:17351063 PMID:20525707 PMID:21377197 RGD:2325990 RGD:5147437 RGD:5147445 NCBI chr 9:6,134,961...6,187,731
Ensembl chr 9:6,141,430...6,149,447
JBrowse link
G IL2RB interleukin 2 receptor subunit beta ISO DNA:SNP: :rs2284033 (human) RGD PMID:18641329 PMID:20860503 RGD:5024942 RGD:5147447 NCBI chr19:19,830,919...19,853,534
Ensembl chr19:19,828,898...19,852,988
JBrowse link
G IL3 interleukin 3 susceptibility ISO DNA:polymorphism:cds:+79T>C(S27P)(human)
DNA:SNP: :rs40401(human)
RGD PMID:15372320 PMID:24684517 RGD:13506914 RGD:13506916 NCBI chr23:34,894,630...34,899,105 JBrowse link
G IL33 interleukin 33 severity
treatment
ISO associated with fungal infectious disease
CTD Direct Evidence: marker/mechanism
associated with viral pneumonia;
RGD
CTD
PMID:19198610 PMID:21804549 PMID:24241537 PMID:25746970 PMID:27472835 More... RGD:39938968 RGD:39939002 NCBI chr12:73,235,585...73,283,665
Ensembl chr12:73,237,406...73,252,436
JBrowse link
G IL4 interleukin 4 treatment
no_association
ISO DNA:polymorphism (human)
mRNA, protein:increase expression:leukocyte, serum
protein:increased expression:respiratory system fluid/secretion
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:lung, spleen
protein:increased expression:lung
DNA:SNP: :589C>T (human)
RGD
CTD
PMID:18211752 PMID:18357729 PMID:20524005 PMID:21103062 PMID:21354484 More... RGD:10402791 RGD:10402799 RGD:2317290 RGD:4889866 RGD:5128500 RGD:5128502 RGD:5128557 RGD:5128560 NCBI chr23:35,492,158...35,501,349
Ensembl chr23:35,492,939...35,501,258
JBrowse link
G IL4R interleukin 4 receptor susceptibility
disease_progression
severity
ISO DNA:polymorphism:cds:p. S478P (human)
OMIM:600807
DNA:polymorphism:cds:p.Q576R (human)
DNA:SNPs: :multiple
DNA:SNPs:cds:p. I75V, Q576R (human)
DNA:polymorphism:cds:p.Q551R (human)
DNA:SNPs:cds:p.E375A, Q551R (human)
DNA:polymorphism::-1902G/A (human)
protein:increased secretion:plasma
DNA:polymorphism:cds:p.I50V (human)
DNA:mutation:cds:p.Q576R (mouse)
RGD
MouseDO
PMID:11398072 PMID:11709756 PMID:12133990 PMID:12940513 PMID:15479272 More... RGD:4890003 RGD:4890024 RGD:4890346 RGD:4890347 RGD:4890348 RGD:4890349 RGD:4890351 RGD:4890352 RGD:4890387 RGD:4890402 RGD:4890404 RGD:4890406 RGD:5128514 RGD:5128553 NCBI chr 5:25,019,638...25,069,732
Ensembl chr 5:25,046,701...25,070,015
JBrowse link
G IL5 interleukin 5 disease_progression
treatment
ISO CTD Direct Evidence: marker/mechanism
protein: increased levels: sputum
protein:increased expression:respiratory system fluid/secretion
DNA:polymorphism:promoter:-703C>T (human)
protein:increased expression:lungs, respiratory system fluid/secretion
RGD
CTD
PMID:7540862 PMID:9182686 PMID:9493449 PMID:11159041 PMID:15502111 More... RGD:11354973 RGD:4145461 RGD:4890938 RGD:4890940 RGD:4890947 RGD:4890948 RGD:4890962 RGD:4890963 RGD:5687140 RGD:5687144 RGD:5687189 NCBI chr23:35,360,143...35,375,169
Ensembl chr23:35,360,506...35,362,178
JBrowse link
G IL5RA interleukin 5 receptor subunit alpha ISO DNA:SNPs (human)
DNA:SNP: :c.25091G>A (human)
RGD PMID:10224351 PMID:10848907 PMID:16217591 PMID:17276963 PMID:20513521 More... RGD:5128614 RGD:5128617 RGD:5128623 RGD:5128625 RGD:5128626 RGD:5128627 NCBI chr22:39,156,711...39,199,394
Ensembl chr22:39,158,023...39,192,861
JBrowse link
G IL6 interleukin 6 ISO protein:increased expression:lung
CTD Direct Evidence: marker/mechanism
associated with Hypersensitivity;protein:increased expression:sputum
RGD
CTD
PMID:20658762 PMID:20816188 PMID:20840469 PMID:21115736 PMID:29902480 RGD:4143265 RGD:4143266 RGD:4143271 RGD:5128630 NCBI chr21:35,577,513...35,582,385
Ensembl chr21:35,577,939...35,582,237
JBrowse link
G IL6R interleukin 6 receptor ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:17496315 PMID:21115736 PMID:29902480 RGD:5128630 RGD:5128662 NCBI chr20:9,345,723...9,418,963
Ensembl chr20:9,361,152...9,396,610
JBrowse link
G IL9 interleukin 9 ISO protein:increased expression:sputum, macrophage, cytoplasm
protein:increased expression:respiratory system fluid/secretion
RGD PMID:12153980 PMID:15303135 PMID:15531759 PMID:17446528 PMID:21356110 RGD:5128686 RGD:5128690 RGD:5128691 RGD:5128700 RGD:5128707 NCBI chr23:38,641,228...38,645,810
Ensembl chr23:38,641,741...38,645,276
JBrowse link
G IL9R interleukin 9 receptor ISO RGD PMID:10629460 RGD:5128704 NCBI chr  X:130,006,399...130,019,191
Ensembl chr  X:130,006,899...130,020,894
JBrowse link
G IRAK3 interleukin 1 receptor associated kinase 3 susceptibility ISO ClinVar Annotator: match by term: Asthma-related traits, susceptibility to, 5 OMIM
ClinVar
PMID:17503328 NCBI chr11:61,868,817...61,920,896
Ensembl chr11:61,869,173...61,920,406
JBrowse link
G IRF1 interferon regulatory factor 1 susceptibility
no_association
ISO DNA:repeat:intron (human)
DNA:polymorphisms:promoter, cds:-300G>T, 4396A>G, 6355G>A (human)
protein:increased expression:respiratory tract epithelium
RGD PMID:10225979 PMID:11069564 PMID:16961714 RGD:5128723 RGD:5128724 RGD:5128726 NCBI chr23:35,309,058...35,317,765
Ensembl chr23:35,307,772...35,316,763
JBrowse link
G IRF3 interferon regulatory factor 3 ISO RGD PMID:20673978 RGD:5128793 NCBI chr 6:42,835,285...42,841,487
Ensembl chr 6:42,831,203...42,840,796
JBrowse link
G ITGB3 integrin subunit beta 3 ISO DNA:SNPs: : RGD PMID:17556058 RGD:5037230 NCBI chr16:59,372,171...59,431,434
Ensembl chr16:59,374,889...59,410,857
JBrowse link
G ITGB6 integrin subunit beta 6 ISO OMIM:600807 MouseDO NCBI chr10:45,506,355...45,650,979
Ensembl chr10:45,504,987...45,595,543
JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 ISO RGD PMID:21777465 RGD:5147661 NCBI chr22:40,574,569...40,925,857
Ensembl chr22:40,574,374...40,926,842
JBrowse link
G KDR kinase insert domain receptor ISO associated with Rhinitis,Allergic,Seasonal;protein:increased expression:nasal cavity of mucosa: RGD PMID:17651148 PMID:20921519 RGD:5684385 RGD:8551771 NCBI chr 7:13,435,059...13,482,236
Ensembl chr 7:13,435,096...13,482,771
JBrowse link
G KIF3A kinesin family member 3A ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chr23:35,496,770...35,554,536
Ensembl chr23:35,514,130...35,551,472
JBrowse link
G KRT19 keratin 19 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15478392 NCBI chr16:64,714,497...64,719,805
Ensembl chr16:64,714,970...64,719,678
JBrowse link
G LEP leptin ISO protein:increased expression:plasma RGD PMID:19705789 RGD:5128781 NCBI chr21:97,056,913...97,071,161
Ensembl chr21:97,057,529...97,071,220
JBrowse link
G LGALS3 galectin 3 treatment ISO RGD PMID:16424226 RGD:9685213 NCBI chr24:32,311,343...32,328,335
Ensembl chr24:32,311,271...32,328,339
JBrowse link
G LOC103221883 uncharacterized LOC103221883 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19426955 PMID:21611147 NCBI chr 4:55,148,012...56,665,684
Ensembl chr 4:55,153,563...55,390,027
JBrowse link
G LOC103223672 low affinity immunoglobulin gamma Fc region receptor II-b ISO RGD PMID:20179765 RGD:11344929 NCBI chr20:2,398,425...2,413,328 JBrowse link
G LOC103224275 glutathione S-transferase Mu 1 resistance
susceptibility
ISO DNA:deletion: :
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:11075422 PMID:16870661 PMID:17651144 PMID:18988661 PMID:21051083 RGD:4140921 RGD:4142509 RGD:5490962 NCBI chr20:23,854,969...23,861,634 JBrowse link
G LOC103232241 cysteinyl leukotriene receptor 1 ISO RGD PMID:16387808 PMID:17689528 RGD:4781449 RGD:4843543 NCBI chr  X:67,218,777...67,300,655
Ensembl chr  X:67,220,048...67,221,061
JBrowse link
G LOC103233057 C-C motif chemokine 22 ISO mRNA:increased expression:lung
protein:increased expression:respiratory system fluid/secretion
RGD PMID:10384142 PMID:15993846 PMID:18316417 RGD:2306304 RGD:4891474 RGD:4891475 NCBI chr 5:43,297,206...43,305,662
Ensembl chr 5:43,297,897...43,305,642
JBrowse link
G LOC103233058 fractalkine ISO protein:increased expression:plasma RGD PMID:14657873 RGD:4891906 NCBI chr 5:43,310,711...43,323,533
Ensembl chr 5:43,310,753...43,323,529
JBrowse link
G LOC103233229 cadherin-1 ISO RGD PMID:21540309 RGD:5132878 NCBI chr 5:58,578,244...58,679,677
Ensembl chr 5:58,578,146...58,679,541
JBrowse link
G LOC103233451 cytochrome b-245 light chain susceptibility ISO DNA:polymorphism: :-930A>G (human)
DNA:SNPs: :-930A>G, 242C>T, 640A>G (human)
RGD PMID:18716406 PMID:19459419 RGD:4311041 RGD:4772770 NCBI chr 5:74,023,134...74,030,793
Ensembl chr 5:74,023,082...74,030,750
JBrowse link
G LOC103233689 thromboxane A2 receptor severity
susceptibility
ISO DNA:polymorphism:cds:924T>C(human)
ClinVar Annotator: match by term: Asthma
RGD
ClinVar
PMID:2955539 PMID:7929844 PMID:8428006 PMID:8613548 PMID:12000493 More... RGD:11059534 RGD:11059535 NCBI chr 6:3,354,358...3,365,779
Ensembl chr 6:3,355,314...3,359,761
JBrowse link
G LOC103234663 interferon lambda-1 exacerbates ISO associated with common cold;mRNA:decreased expression:sputum (human)
associated with common cold;protein:increased expression: nasal cavity (human)
RGD PMID:22135341 PMID:25784275 RGD:126848770 RGD:126848775 NCBI chr 6:33,901,382...33,904,356
Ensembl chr 6:33,901,801...33,903,894
JBrowse link
G LOC103243260 corticotropin-releasing factor receptor 1 ISO DNA:SNP: :RS242941 (human)
DNA:SNPs: :rs1876828, rs242939, rs242941 (human)
RGD PMID:16113459 PMID:19663668 RGD:5147485 RGD:5147488 NCBI chr16:60,070,156...60,120,857
Ensembl chr16:60,070,066...60,120,712
JBrowse link
G LOC103246958 caspase recruitment domain-containing protein 11 susceptibility ISO RGD PMID:16751370 RGD:11100037 NCBI chr28:18,657,941...18,714,202 JBrowse link
G LTA lymphotoxin alpha susceptibility
no_association
ISO DNA:polymorphism:intron
DNA:polymorphisms:promoter
RGD PMID:12530118 PMID:15969671 PMID:17536219 PMID:18947013 RGD:4143254 RGD:4143370 RGD:4143371 RGD:4143373
G LTA4H leukotriene A4 hydrolase ISO mRNA:increased expression:lung, cerebral cortex (rat) RGD PMID:15715933 RGD:2316607 NCBI chr11:91,371,383...91,413,396
Ensembl chr11:91,371,383...91,406,542
JBrowse link
G MBL2 mannose binding lectin 2 susceptibility ISO associated with Bronchiolitis;DNA:polymorphism:exon:
DNA:SNP:cds:p.G54D(human)
RGD PMID:22512728 PMID:22674410 RGD:12910828 RGD:8693709 NCBI chr 9:78,389,534...78,394,753
Ensembl chr 9:78,389,947...78,396,079
JBrowse link
G MEFV MEFV innate immunity regulator, pyrin susceptibility ISO DNA:mutations:exons RGD PMID:18219832 RGD:5129186 NCBI chr 5:2,971,323...2,991,501 JBrowse link
G MHC-DPA1 major histocompatibility complex, class II, DP alpha 1 susceptibility ISO DNA:polymorphism: : RGD PMID:21814517 RGD:13506911 NCBI chr17:39,009,361...39,017,978 JBrowse link
G MHC-DPB1 major histocompatibility complex, class II, DP beta 1 susceptibility ISO DNA:polymorphisms: :
DNA:haplotype
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:16792590 PMID:17956852 PMID:21217921 PMID:21814517 RGD:13506911 RGD:5143938 NCBI chr17:38,996,329...39,007,097 JBrowse link
G MHC-DQA1 major histocompatibility complex, class II, DQ alpha 1 ISO DNA:polymorphism (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphisms (human)
RGD
CTD
PMID:10051703 PMID:10792356 PMID:11802952 PMID:12890388 PMID:19052351 RGD:1331670 RGD:5147617 RGD:5147799 RGD:5147831 NCBI chr17:39,422,445...39,428,777
Ensembl chr17:39,420,134...39,428,871
JBrowse link
G MHC-DRA major histocompatibility complex, class II, DR alpha susceptibility ISO DNA:polymorphisms: : RGD PMID:20159242 RGD:13506913 NCBI chr17:39,623,324...39,628,464
Ensembl chr17:39,622,402...39,629,261
JBrowse link
G MIF macrophage migration inhibitory factor severity ISO DNA:repeats:promoter
DNA:SNP:promoter:rs755622(human)
protein:increased expression:bronchoalveolar lavage fluid
RGD PMID:9637721 PMID:16186482 PMID:16455830 PMID:17373669 PMID:19317738 RGD:1641985 RGD:4891035 RGD:4891043 RGD:4891052 RGD:4891059 NCBI chr19:7,000,837...7,001,700
Ensembl chr19:7,000,793...7,001,757
JBrowse link
G MMP1 matrix metallopeptidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24469321 NCBI chr 1:94,167,507...94,177,357
Ensembl chr 1:94,167,219...94,176,767
JBrowse link
G MMP10 matrix metallopeptidase 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16926187 NCBI chr 1:94,147,995...94,158,315
Ensembl chr 1:94,148,087...94,158,097
JBrowse link
G MMP9 matrix metallopeptidase 9 ISO mRNA, protein:increased expression:lung
CTD Direct Evidence: marker/mechanism
DNA:SNP: : rs2664538(human)
protein:increased expression:serum
RGD
CTD
PMID:11742282 PMID:15131573 PMID:16191269 PMID:19361849 PMID:19940022 More... RGD:2325953 RGD:5129204 RGD:5129522 RGD:5129687 RGD:5130859 NCBI chr 2:17,867,267...17,874,757
Ensembl chr 2:17,867,177...17,874,712
JBrowse link
G MPO myeloperoxidase susceptibility ISO DNA:polymorphism: :−463G > A (human)
protein:increased expression:serum
RGD PMID:10731862 PMID:19544176 RGD:5130989 RGD:5130994 NCBI chr16:35,120,194...35,130,851
Ensembl chr16:35,120,581...35,130,671
JBrowse link
G MS4A2 membrane spanning 4-domains A2 susceptibility ISO DNA:SNPs: : rs556917, rs502581, rs502419 (human)
Atopy and bronchial hyperresponsiveness, OMIM:147050 DNA:polymorphism:CDS:amino acid E237G
DNA:SNPs:multiple:, rs573790, rs2583476, rs569108
DNA:SNP: : -109C>T (human)
RGD PMID:8817330 PMID:19218813 PMID:19862939 PMID:21320344 RGD:1599903 RGD:5131092 RGD:5131149 RGD:5131151 NCBI chr 1:13,657,842...13,666,314
Ensembl chr 1:13,654,696...13,665,925
JBrowse link
G MTHFR methylenetetrahydrofolate reductase ISO DNA:transition:cds:g.677C>T (human) RGD PMID:20456312 RGD:4891145 NCBI chr20:119,987,667...120,003,611
Ensembl chr20:119,990,133...120,002,950
JBrowse link
G MUC1 mucin 1, cell surface associated ISO protein:increased expression:serum RGD PMID:11802251 RGD:5131281 NCBI chr20:8,641,701...8,646,739
Ensembl chr20:8,642,842...8,646,962
JBrowse link
G MUC2 mucin 2, oligomeric mucus/gel-forming ISO associated with hypersensitivity RGD PMID:11062147 PMID:14594655 RGD:5131178 RGD:7349354 NCBI chr 1:893,554...926,854 JBrowse link
G MUC5AC mucin 5AC, oligomeric mucus/gel-forming treatment ISO protein:increased expression:lung
mRNA,protein:increased expression:lung
mRNA, protein:increased expression:lung
RGD PMID:14594655 PMID:17590487 PMID:17698377 PMID:21549818 PMID:21780541 RGD:2324962 RGD:5131204 RGD:7349354 RGD:7349407 RGD:7364729 NCBI chr 1:981,515...1,018,242 JBrowse link
G MUC5B mucin 5B, oligomeric mucus/gel-forming ISO protein:altered expression:sputum RGD PMID:11587997 PMID:11802783 RGD:5131252 RGD:7364763 NCBI chr 1:1,040,756...1,083,246
Ensembl chr 1:1,042,110...1,081,240
JBrowse link
G MUC7 mucin 7, secreted ISO ClinVar Annotator: match by term: Asthma, protection against ClinVar
OMIM
PMID:11378823 PMID:16759176 PMID:28492532 NCBI chr 7:18,982,090...18,990,627
Ensembl chr 7:18,982,103...18,989,955
JBrowse link
G MYB MYB proto-oncogene, transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19198610 NCBI chr13:38,203,923...38,242,148
Ensembl chr13:38,203,731...38,241,864
JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor ameliorates ISO RGD PMID:26882889 RGD:11531666 NCBI chr15:1,276,804...1,281,811
Ensembl chr15:1,276,798...1,281,166
JBrowse link
G MYLK myosin light chain kinase ISO RGD PMID:17472811 RGD:4891492 NCBI chr22:57,032,264...57,259,253
Ensembl chr22:57,065,331...57,257,464
JBrowse link
G NAT2 N-acetyltransferase 2 susceptibility ISO Asthma, Aspirin-Induced; DNA:polymorphism: :
DNA:polymorphisms: :
RGD PMID:16924569 PMID:20602614 RGD:5131600 RGD:5131606 NCBI chr 8:16,451,144...16,494,961
Ensembl chr 8:16,493,749...16,494,621
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 severity ISO mRNA:increased expression:bronchoalveolar lavage cell, peripheral blood mononuclear cell (human) RGD PMID:21514635 RGD:6893376 NCBI chr10:62,789,647...62,825,651
Ensembl chr10:62,790,124...62,825,339
JBrowse link
G NGF nerve growth factor severity ISO protein:increased expression:lung, serum
protein:increased expression:blood, eosinophil
RGD PMID:11737043 PMID:12752594 PMID:17164945 PMID:17497413 RGD:4891068 RGD:4891108 RGD:4891122 RGD:4891123 NCBI chr20:18,361,795...18,413,987
Ensembl chr20:18,413,108...18,413,833
JBrowse link
G NGFR nerve growth factor receptor ISO RGD PMID:12540484 PMID:16603479 RGD:5144070 RGD:5144072 NCBI chr16:69,894,000...69,914,209
Ensembl chr16:69,894,139...69,912,189
JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 susceptibility ISO DNA:SNP: :rs2075817 (human)
DNA:insertion:cds:
RGD PMID:15718249 PMID:16918516 RGD:5131518 RGD:5131519 NCBI chr21:27,907,628...27,957,621
Ensembl chr21:27,926,710...27,957,619
JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 susceptibility ISO DNA:polymorphisms:intron, exon/3'UTR (rs1077861, rs3135500) (human) RGD PMID:16008671 PMID:21051079 RGD:5131477 RGD:5508757 NCBI chr 5:36,492,158...36,531,766
Ensembl chr 5:36,496,414...36,530,499
JBrowse link
G NOS1 nitric oxide synthase 1 susceptibility ISO DNA:repeats: :
DNA:repeats:intron
DNA:repeats:exon
RGD PMID:10673365 PMID:10833424 PMID:14767694 PMID:20609134 RGD:5132615 RGD:5132860 RGD:5132863 RGD:5132869 NCBI chr11:112,642,374...112,673,882 JBrowse link
G NOS2 nitric oxide synthase 2 severity
disease_progression
no_association
ISO protein:increased expression, increased activity:lung (rat)
DNA:SNP:exon:p.S608L (human)
CTD Direct Evidence: marker/mechanism
protein:increased expression:lung, bronchoalveolar lavage fluid
DNA:repeats:promoter
associated with Rhinitis, Allergic, Seasonal; protein:increased expression:nasal mucosa
DNA:repeats:promoter, introns (human)
mRNA:increased expression:monocyte
DNA:repeat:promoter
RGD
CTD
PMID:16540403 PMID:16703578 PMID:17161822 PMID:17177683 PMID:17189532 More... RGD:4891419 RGD:4891480 RGD:4891508 RGD:4891910 RGD:4891924 RGD:4891925 RGD:4891927 RGD:4891953 RGD:4891957 RGD:5509073 NCBI chr16:21,533,011...21,576,645
Ensembl chr16:21,533,484...21,574,257
JBrowse link
G NOS3 nitric oxide synthase 3 susceptibility ISO DNA:repeats:intron
DNA:polymorphisms:promoter:c. -786C>T, -691C>T (human)
DNA:snps, repeat, haplotype:promoter, introns, exons:multiple (human)
RGD PMID:16081038 PMID:16837812 PMID:18486767 RGD:4892053 RGD:4892058 RGD:4892062 NCBI chr21:119,174,829...119,196,840 JBrowse link
G NPSR1 neuropeptide S receptor 1 susceptibility ISO ClinVar Annotator: match by term: Asthma-related traits, susceptibility to, 2 OMIM
ClinVar
PMID:15073379 NCBI chr21:23,558,313...23,784,475 JBrowse link
G NPY neuropeptide Y ISO CTD Direct Evidence: marker/mechanism CTD PMID:9731035 NCBI chr21:34,068,533...34,076,205
Ensembl chr21:34,068,530...34,075,127
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 susceptibility ISO DNA:SNP:exon:c. 609C>T (human)
DNA:SNP:exon:c.609C>T (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:19027876 PMID:19591959 PMID:20049212 RGD:5135005 RGD:5135006 NCBI chr 5:57,676,547...57,695,434
Ensembl chr 5:57,675,981...57,716,599
JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 treatment
severity
susceptibility
ISO protein:increased expression, decreased activity:leukocyte, mononuclear
DNA:polymorphism:intron
RGD PMID:15295049 PMID:18396779 PMID:18799869 PMID:20727335 PMID:21113676 RGD:4892328 RGD:4892568 RGD:4892594 RGD:4892609 RGD:7174728 NCBI chr23:45,904,926...46,031,804
Ensembl chr23:45,904,873...46,031,125
JBrowse link
G NTF3 neurotrophin 3 ISO protein:increased expression:lung, serum RGD PMID:11737043 PMID:17497413 RGD:4891068 RGD:4891123 NCBI chr11:5,477,208...5,542,404 JBrowse link
G NTF4 neurotrophin 4 ISO protein:increased expression:lung, serum RGD PMID:17497413 RGD:4891068 NCBI chr 6:42,254,693...42,284,899
Ensembl chr 6:42,279,190...42,279,822
JBrowse link
G NTRK1 neurotrophic receptor tyrosine kinase 1 ISO mRNA:increased expression:lung: RGD PMID:16708804 PMID:20934630 RGD:5684766 RGD:5684772 NCBI chr20:6,987,903...7,027,381
Ensembl chr20:6,987,905...7,008,670
JBrowse link
G ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21150878 PMID:25256354 NCBI chr16:66,243,503...66,249,800
Ensembl chr16:66,243,539...66,250,167
JBrowse link
G P2RY12 purinergic receptor P2Y12 ISO RGD PMID:19822647 PMID:22010907 RGD:6480532 RGD:6480533 NCBI chr15:39,315,140...39,361,614
Ensembl chr15:39,359,612...39,360,637
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 treatment ISO protein:increased activation:lung, blood, mononuclear cell
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:12594058 PMID:18261157 PMID:26205779 RGD:11073727 RGD:5683910 NCBI chr25:3,350,798...3,405,040 JBrowse link
G PDCD1 programmed cell death 1 treatment ISO associated with Chlamydia pneumonia RGD PMID:26378990 RGD:41412180 NCBI chr10:127,877,383...127,886,234
Ensembl chr10:127,878,554...127,886,088
JBrowse link
G PDE4B phosphodiesterase 4B ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chr20:66,729,561...67,297,729
Ensembl chr20:66,728,664...66,771,691
JBrowse link
G PDGFB platelet derived growth factor subunit B ISO protein: increased expression RGD PMID:21216974 RGD:6483071 NCBI chr19:21,865,792...21,888,068
Ensembl chr19:21,863,768...21,886,395
JBrowse link
G PGF placental growth factor ISO RGD PMID:22268141 RGD:6483605 NCBI chr24:52,160,904...52,174,493
Ensembl chr24:52,161,787...52,173,989
JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO RGD PMID:18754810 RGD:6482695 NCBI chr21:75,781,812...75,823,404
Ensembl chr21:75,784,648...75,825,496
JBrowse link
G PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 ISO RGD PMID:18188456 RGD:8693422 NCBI chr 6:8,920,860...8,935,943
Ensembl chr 6:8,920,785...8,936,033
JBrowse link
G PLA2G4A phospholipase A2 group IVA ISO RGD PMID:15557087 RGD:1642462 NCBI chr25:42,443,480...42,590,895
Ensembl chr25:42,443,385...42,590,431
JBrowse link
G PLA2G7 phospholipase A2 group VII ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:10733466 RGD:1581025 NCBI chr17:25,538,645...25,571,230
Ensembl chr17:25,538,438...25,574,269
JBrowse link
G PLAU plasminogen activator, urokinase ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:18519237 PMID:21912604 RGD:4892037 NCBI chr 9:57,452,904...57,459,345
Ensembl chr 9:57,452,761...57,459,286
JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:22205926 NCBI chr23:36,999,110...37,028,916
Ensembl chr23:36,997,078...37,029,280
JBrowse link
G PRF1 perforin 1 ISO RGD PMID:21426642 PMID:22250087 RGD:6482815 RGD:6482818 NCBI chr 9:60,692,544...60,698,000
Ensembl chr 9:60,692,600...60,698,465
JBrowse link
G PRG2 proteoglycan 2, pro eosinophil major basic protein severity
disease_progression
no_association
ISO mRNA:increased expression:eosinophil:
associated with viral infection;mRNA:increased expression:sputum:
associated with cough;protein:increased expression:sputum:
RGD PMID:11067904 PMID:16982448 PMID:22022864 PMID:24450586 RGD:13506941 RGD:13506942 RGD:13506943 RGD:13506944 NCBI chr 1:15,850,181...15,854,511
Ensembl chr 1:15,850,913...15,854,517
JBrowse link
G PRMT1 protein arginine methyltransferase 1 ISO mRNA:increased expression:lung RGD PMID:20423833 RGD:9491823 NCBI chr 6:42,854,873...42,863,113
Ensembl chr 6:42,854,918...42,863,014
JBrowse link
G PRMT2 protein arginine methyltransferase 2 ISO mRNA:increased expression:lung, spleen RGD PMID:20423833 RGD:9491823 NCBI chr 2:90,225,051...90,256,541
Ensembl chr 2:90,225,346...90,256,558
JBrowse link
G PRMT3 protein arginine methyltransferase 3 ISO mRNA:increased expression:lung RGD PMID:20423833 RGD:9491823 NCBI chr 1:44,486,165...44,621,002
Ensembl chr 1:44,485,880...44,620,936
JBrowse link
G PRMT5 protein arginine methyltransferase 5 ISO mRNA:increased expression:lung, spleen RGD PMID:20423833 RGD:9491823 NCBI chr29:23,288,458...23,297,746
Ensembl chr29:23,288,835...23,297,518
JBrowse link
G PROC protein C, inactivator of coagulation factors Va and VIIIa treatment ISO RGD PMID:26381519 RGD:11099992 NCBI chr10:2,789,227...2,799,783
Ensembl chr10:2,789,277...2,799,531
JBrowse link
G PTEN phosphatase and tensin homolog ISO CTD Direct Evidence: therapeutic CTD PMID:17982072 NCBI chr 9:81,308,058...81,412,386
Ensembl chr 9:81,309,099...81,409,146
JBrowse link
G PTGDR prostaglandin D2 receptor susceptibility ISO OMIM NCBI chr24:29,347,796...29,359,783
Ensembl chr24:29,350,749...29,359,754
JBrowse link
G PTGDR2 prostaglandin D2 receptor 2 ISO Aspirin exacerbated asthma
CTD Direct Evidence: therapeutic
RGD
CTD
PMID:18757520 PMID:19392992 PMID:19796209 PMID:27103662 RGD:5135018 RGD:5135019 RGD:5135020 NCBI chr 1:12,989,750...12,994,979
Ensembl chr 1:12,992,188...12,993,378
JBrowse link
G PTGER3 prostaglandin E receptor 3 treatment ISO RGD PMID:23221044 RGD:10043366 NCBI chr20:62,093,830...62,293,360
Ensembl chr20:62,095,458...62,174,959
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 susceptibility
severity
ISO mRNA, protein:increased expression:lung:
DNA:SNP: :8473T>C (human)
DNA:SNP: :rs689465 (human)
mRNA:increased expression:lung
RGD PMID:15316498 PMID:17573729 PMID:18097056 PMID:18489027 PMID:19342146 More... RGD:5135514 RGD:5135515 RGD:5135522 RGD:5135526 RGD:5135534 RGD:5143923 RGD:5143931 NCBI chr25:42,733,535...42,742,463
Ensembl chr25:42,734,771...42,742,429
JBrowse link
G PYHIN1 pyrin and HIN domain family member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21804549 NCBI chr20:4,967,123...5,006,172
Ensembl chr20:4,967,224...5,006,035
JBrowse link
G RAD50 RAD50 double strand break repair protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:24241537 NCBI chr23:35,375,206...35,458,801
Ensembl chr23:35,375,305...35,458,622
JBrowse link
G RHOA ras homolog family member A ISO RGD PMID:18391481 RGD:2298885 NCBI chr22:10,757,381...10,809,257
Ensembl chr22:10,757,337...10,772,704
JBrowse link
G RUNX1 RUNX family transcription factor 1 ISO DNA:SNPs: :multiple RGD PMID:21803869 RGD:6482835 NCBI chr 2:78,819,189...79,082,491
Ensembl chr 2:78,819,194...78,924,495
JBrowse link
G RUNX3 RUNX family transcription factor 3 ISO OMIM:600807 MouseDO NCBI chr20:107,769,244...107,802,154
Ensembl chr20:107,736,683...107,802,307
JBrowse link
G SCGB1A1 secretoglobin family 1A member 1 susceptibility ISO associated with allergic rhinitis; DNA:SNP:exon:38G>A (human)
ClinVar Annotator: match by term: Asthma, susceptibility to
RGD
ClinVar
PMID:9550363 PMID:9643286 PMID:12100044 PMID:21255142 RGD:5144226 NCBI chr 1:11,470,091...11,474,915
Ensembl chr 1:11,470,195...11,474,149
JBrowse link
G SCGB3A2 secretoglobin family 3A member 2 susceptibility
severity
no_association
ISO ClinVar Annotator: match by term: Asthma, susceptibility to
DNA:SNP:promoter:-112G>A (human)
OMIM
ClinVar
RGD
PMID:11813133 PMID:18089940 PMID:18201431 RGD:5144230 RGD:5144231 NCBI chr23:50,327,428...50,417,518
Ensembl chr23:50,414,139...50,417,373
JBrowse link
G SELL selectin L ISO RGD PMID:21437035 PMID:21515793 RGD:5685685 RGD:5685696 NCBI chr25:59,345,080...59,365,684
Ensembl chr25:59,345,069...59,366,946
JBrowse link
G SERPINA1 serpin family A member 1 ISO Fisher rats, shown to exhibit hyperactive airway responses at 14 days of age, had higher transcript and protein levels of Serpina1 than same age Brown Norway rats. RGD PMID:20118217 RGD:5131869 NCBI chr24:72,158,521...72,171,139
Ensembl chr24:72,156,784...72,163,500
JBrowse link
G SERPINE1 serpin family E member 1 severity
no_association
susceptibility
ISO protein:increased activity, increased expression:plasma, lung
protein:increased expression:plasma
DNA:polymorphism:promoter:rs1799768 (human)
RGD PMID:18594148 PMID:19063817 PMID:19604112 PMID:19703828 RGD:4144831 RGD:4144832 RGD:4144833 RGD:4144836 NCBI chr28:12,047,520...12,060,662
Ensembl chr28:12,047,529...12,060,202
JBrowse link
G SFTPB surfactant protein B ISO mRNA, protein:decreased expression:lung
protein:increased expression:lung
protein:decreased expression:lung, Clara cell
RGD PMID:11472974 PMID:15816355 PMID:16629790 PMID:18926058 RGD:4143289 RGD:4143398 RGD:4143462 RGD:4143465 NCBI chr14:21,487,424...21,497,491
Ensembl chr14:21,488,387...21,499,850
JBrowse link
G SFTPC surfactant protein C susceptibility ISO protein:increased expression:lung
mRNA, protein:decreased expression:lung
DNA:polymorphism: :p.A53T (human)
RGD PMID:11472974 PMID:16629790 PMID:19910179 RGD:4143462 RGD:4143465 RGD:4144063 NCBI chr 8:20,229,756...20,233,568
Ensembl chr 8:20,230,870...20,234,020
JBrowse link
G SFTPD surfactant protein D ISO associated with Bronchitis;protein:increased expression:lung
mRNA, protein:increased expression:lung
RGD PMID:11472974 PMID:16629790 PMID:16839409 PMID:18266831 PMID:18802356 RGD:4143462 RGD:4143465 RGD:4143508 RGD:4143516 RGD:4143517 NCBI chr 9:51,809,241...51,820,974
Ensembl chr 9:51,811,052...51,820,650
JBrowse link
G SLC11A1 solute carrier family 11 member 1 ISO RGD PMID:12847242 RGD:5684966 NCBI chr10:104,276,553...104,288,466 JBrowse link
G SLC18A3 solute carrier family 18 member A3 ISO RGD PMID:17328924 RGD:5686690 NCBI chr 9:42,216,187...42,219,665
Ensembl chr 9:42,216,568...42,218,166
JBrowse link
G SLC22A1 solute carrier family 22 member 1 ISO RGD PMID:17328924 RGD:5686690 NCBI chr13:87,744,600...87,780,846
Ensembl chr13:87,745,023...87,781,073
JBrowse link
G SLC5A7 solute carrier family 5 member 7 ISO mRNA:decreased expression:lung RGD PMID:17328924 RGD:5686690 NCBI chr14:11,346,281...11,373,754
Ensembl chr14:11,347,861...11,370,297
JBrowse link
G SLC6A4 solute carrier family 6 member 4 susceptibility ISO DNA:repeat:intron (human) RGD PMID:19806585 RGD:4889460 NCBI chr16:23,929,196...23,969,665
Ensembl chr16:23,927,311...23,955,616
JBrowse link
G SOD1 superoxide dismutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22867017 NCBI chr 2:60,461,219...60,472,999 JBrowse link
G SOD2 superoxide dismutase 2 ISO RGD PMID:15743779 RGD:1581231 NCBI chr13:87,284,537...87,297,998
Ensembl chr13:87,280,686...87,297,974
JBrowse link
G STAT4 signal transducer and activator of transcription 4 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:18211752 PMID:28807506 RGD:2317290 NCBI chr10:76,553,626...76,708,540
Ensembl chr10:76,553,606...76,674,928
JBrowse link
G STAT6 signal transducer and activator of transcription 6 treatment ISO RGD PMID:16083555 PMID:19087723 RGD:7244151 RGD:7244153 NCBI chr11:53,005,378...53,020,899
Ensembl chr11:53,006,145...53,021,203
JBrowse link
G TAC1 tachykinin precursor 1 ISO protein:increased expression:lung RGD PMID:11031342 RGD:5147836 NCBI chr21:51,339,085...51,347,561
Ensembl chr21:51,339,095...51,347,550
JBrowse link
G TACR1 tachykinin receptor 1 ISO mRNA:increased expression:lung
mRNA,protein:increased expression:lung
RGD PMID:8240667 PMID:16409782 PMID:17392578 RGD:2304339 RGD:5147475 RGD:5147645 NCBI chr14:32,080,319...32,236,556
Ensembl chr14:32,083,615...32,233,596
JBrowse link
G TACR2 tachykinin receptor 2 ISO DNA:SNP:cds:p.G231E (human) RGD PMID:19880429 PMID:20175803 RGD:5147640 RGD:5147641 NCBI chr 9:61,902,565...61,915,402
Ensembl chr 9:61,903,477...61,914,558
JBrowse link
G TAP1 transporter 1, ATP binding cassette subfamily B member susceptibility ISO DNA:polymorphism: : RGD PMID:12640628 RGD:5147845 NCBI chr17:39,252,000...39,260,195 JBrowse link
G TBX21 T-box transcription factor 21 ISO CTD Direct Evidence: marker/mechanism
OMIM:600807
CTD
MouseDO
PMID:15806396 NCBI chr16:68,131,258...68,145,579
Ensembl chr16:68,131,536...68,144,415
JBrowse link
G TGFB1 transforming growth factor beta 1 onset
no_association
ISO DNA:SNPs:promoter, exon:multiple (human)
DNA:SNP: :-509C>T (human)
DNA:polymorphism: :-509C>T (human)
DNA:SNP:cds:915G>C (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphisms: :multiple (human)
mRNA:increased expression:lung
protein:increased expression:serum
RGD
CTD
PMID:16365456 PMID:17673695 PMID:18366906 PMID:18711258 PMID:19046298 More... RGD:4143443 RGD:4145113 RGD:4145132 RGD:4145139 RGD:4145142 RGD:4145143 RGD:4145144 RGD:4145280 RGD:4145295 RGD:4145297 RGD:4145299 NCBI chr 6:35,651,583...35,674,387
Ensembl chr 6:35,648,677...35,674,365
JBrowse link
G THBD thrombomodulin ISO RGD PMID:20709825 RGD:5684984 NCBI chr 2:52,041,950...52,045,946
Ensembl chr 2:52,043,746...52,045,626
JBrowse link
G TIMP3 TIMP metallopeptidase inhibitor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16926187 NCBI chr19:15,621,609...15,684,118
Ensembl chr19:15,622,431...15,680,449
JBrowse link
G TLR1 toll like receptor 1 susceptibility ISO DNA:SNP (human) RGD PMID:18547625 RGD:4889528 NCBI chr27:11,482,307...11,490,847
Ensembl chr27:11,488,294...11,490,654
JBrowse link
G TLR10 toll like receptor 10 susceptibility ISO DNA:SNP (human) RGD PMID:18547625 RGD:4889528 NCBI chr27:11,486,273...11,515,841
Ensembl chr27:11,512,239...11,514,671
JBrowse link
G TLR2 toll like receptor 2 susceptibility
severity
ISO DNA:SNP: :rs4696480 (human)
DNA:SNP: :rs3804100 (human)
DNA:polymorphism:cds:p.R753Q(human)
DNA:SNP: :rs7656411 (human)
DNA:SNP: :596T>C (human)
RGD PMID:18202345 PMID:18787777 PMID:19096003 PMID:19148143 PMID:20685742 More... RGD:2312679 RGD:4144171 RGD:4144228 RGD:4145334 RGD:4145343 RGD:4145352 RGD:7800732 NCBI chr 7:100,239,533...100,565,955
Ensembl chr 7:100,258,441...100,260,795
JBrowse link
G TLR3 toll like receptor 3 no_association ISO DNA:snp:cds:p.L412F (human)
Asthma, Virus-Induced; mRNA:increased expression:sputum (human)
RGD PMID:14987294 PMID:17434873 PMID:17610940 PMID:21129050 PMID:21364926 RGD:5128500 RGD:5129226 RGD:5129475 RGD:5129478 RGD:5129493 NCBI chr 7:131,991,068...132,014,366
Ensembl chr 7:131,991,029...132,016,232
JBrowse link
G TLR4 toll like receptor 4 susceptibility
severity
no_association
ISO DNA:SNPs::
protein:decreased expression:leukocytes, mononuclear
DNA:Polymorphism:cds:p.D299G (human)
DNA:polymorphisms:cds:c.896A>G, 1196C>T (human)
DNA:SNPs: :rs10983755, rs1927914 (human)
RGD PMID:15356557 PMID:16266379 PMID:19067129 PMID:19159017 PMID:19330007 More... RGD:4144141 RGD:4144171 RGD:4144176 RGD:4144188 RGD:4144190 RGD:4144198 RGD:4144817 NCBI chr12:21,873,762...21,885,562
Ensembl chr12:21,871,773...21,885,515
JBrowse link
G TLR6 toll like receptor 6 susceptibility ISO DNA:SNP (human)
DNA:SNP: :p.S249P (human)
RGD PMID:15266299 PMID:18547625 RGD:4889528 RGD:4889538 NCBI chr27:11,439,288...11,461,580
Ensembl chr27:11,459,181...11,461,571
JBrowse link
G TNC tenascin C ISO DNA:SNPs: :multiple (human)
CTD Direct Evidence: marker/mechanism
DNA:SNP:exon:p.L1677I (human)
protein:increased expression:bronchus basement membrane
RGD
CTD
PMID:9310019 PMID:16115819 PMID:17125141 PMID:18305139 RGD:4889565 RGD:4889569 RGD:4889572 RGD:4889589 NCBI chr12:24,457,616...24,556,194
Ensembl chr12:24,457,738...24,556,451
JBrowse link
G TNF tumor necrosis factor no_association
susceptibility
ISO DNA:polymorphism:promoter:
associated with obesity; DNA:polymorphism:promoter
ClinVar Annotator: match by term: Asthma, susceptibility to
RGD
OMIM
ClinVar
PMID:8056188 PMID:9818939 PMID:10450718 PMID:11261930 PMID:11506397 More... RGD:4143238 RGD:4143254
G TNFRSF1A TNF receptor superfamily member 1A ISO protein:increased expression:lung (mouse) RGD PMID:20484920 RGD:5131201 NCBI chr11:6,364,544...6,378,880
Ensembl chr11:6,364,330...6,378,902
JBrowse link
G TNIP1 TNFAIP3 interacting protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24453940 NCBI chr23:53,586,243...53,643,599
Ensembl chr23:53,587,008...53,621,489
JBrowse link
G TRPA1 transient receptor potential cation channel subfamily A member 1 severity ISO ovalbumin sensitization
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:19458046 PMID:31969645 RGD:127285811 NCBI chr 8:67,698,067...67,754,407
Ensembl chr 8:67,698,786...67,751,885
JBrowse link
G TSLP thymic stromal lymphopoietin ISO CTD Direct Evidence: marker/mechanism CTD PMID:21804549 NCBI chr23:14,419,820...14,423,331 JBrowse link
G UCN urocortin ISO associated with Hypersensitivity;mRNA, protein:increased expression:lung RGD PMID:16427607 RGD:1642781 NCBI chr14:80,303,210...80,304,910
Ensembl chr14:80,304,416...80,304,790
JBrowse link
G UTS2 urotensin 2 ISO RGD PMID:17045018 RGD:2306832 NCBI chr20:123,903,137...123,910,180 JBrowse link
G VDR vitamin D receptor no_association ISO DNA:SNPs (human)
DNA:SNPs: :multiple (human)
DNA:SNP (human)
DNA:SNP: :rs7975232 (human)
RGD PMID:15282200 PMID:19622139 PMID:20124605 PMID:21103062 RGD:4889854 RGD:4889866 RGD:4889867 RGD:4889868 NCBI chr11:44,062,198...44,126,295
Ensembl chr11:44,065,457...44,166,684
JBrowse link
G VEGFA vascular endothelial growth factor A ISO protein:increased expression:sputum
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:11907124 PMID:15201500 PMID:19178538 PMID:19263519 RGD:6892723 NCBI chr17:28,377,959...28,394,508 JBrowse link
G VIP vasoactive intestinal peptide ISO RGD PMID:16782752 PMID:21419198 RGD:5685381 RGD:5685620 NCBI chr13:80,217,602...80,228,320
Ensembl chr13:80,218,572...80,228,278
JBrowse link
G WDR36 WD repeat domain 36 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19198610 NCBI chr23:14,427,459...14,464,125
Ensembl chr23:14,427,487...14,466,704
JBrowse link
Asthma and Nasal Polyps term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MHC-DRA major histocompatibility complex, class II, DR alpha susceptibility ISO DNA:SNPs,haplotype:introns: RGD PMID:22391069 RGD:13506908 NCBI chr17:39,623,324...39,628,464
Ensembl chr17:39,622,402...39,629,261
JBrowse link
G TBX21 T-box transcription factor 21 ISO ClinVar Annotator: match by term: Asthma and nasal polyps ClinVar PMID:15806396 NCBI chr16:68,131,258...68,145,579
Ensembl chr16:68,131,536...68,144,415
JBrowse link
asthma, nasal polyps, and aspirin intolerance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX15 arachidonate 15-lipoxygenase ISO ClinVar Annotator: match by term: Asthma, nasal polyps, and aspirin intolerance ClinVar PMID:17959182 PMID:21558275 PMID:25741868 PMID:30643255 NCBI chr16:4,112,795...4,121,764
Ensembl chr16:4,111,151...4,121,645
JBrowse link
G LTC4S leukotriene C4 synthase ISO ClinVar Annotator: match by term: Asthma, nasal polyps, and aspirin intolerance ClinVar PMID:25741868 NCBI chr23:81,523,784...81,526,297
Ensembl chr23:81,523,775...81,526,179
JBrowse link
G PTGER2 prostaglandin E receptor 2 susceptibility ISO CTD Direct Evidence: marker/mechanism OMIM
CTD
NCBI chr24:29,395,799...29,410,723
Ensembl chr24:29,396,464...29,409,575
JBrowse link
G TBX21 T-box transcription factor 21 susceptibility ISO ClinVar Annotator: match by term: Asthma, nasal polyps, and aspirin intolerance ClinVar
OMIM
PMID:25741868 NCBI chr16:68,131,258...68,145,579
Ensembl chr16:68,131,536...68,144,415
JBrowse link
berylliosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCR5 C-C motif chemokine receptor 5 disease_progression ISO DNA:polymorphisms:5' utr:multiple (human) RGD PMID:20075058 RGD:4892065 NCBI chr22:7,803,794...7,818,112 JBrowse link
G CD28 CD28 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:12952926 NCBI chr10:89,471,710...89,505,152
Ensembl chr10:89,471,730...89,500,387
JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:16766924 NCBI chr20:39,339,948...39,359,980
Ensembl chr20:39,339,908...39,359,430
JBrowse link
G HMOX1 heme oxygenase 1 ISO protein:increased activity:sputum RGD PMID:19453654 RGD:4145349 NCBI chr19:18,144,466...18,157,944
Ensembl chr19:18,144,545...18,157,971
JBrowse link
G IL2RA interleukin 2 receptor subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:8977230 NCBI chr 9:6,134,961...6,187,731
Ensembl chr 9:6,141,430...6,149,447
JBrowse link
G IL6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8428540 NCBI chr21:35,577,513...35,582,385
Ensembl chr21:35,577,939...35,582,237
JBrowse link
G MHC-DPB1 major histocompatibility complex, class II, DP beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8105536 PMID:11551429 PMID:14662898 PMID:15273960 PMID:17927685 More... NCBI chr17:38,996,329...39,007,097 JBrowse link
G TGFB1 transforming growth factor beta 1 severity ISO CTD Direct Evidence: marker/mechanism
DNA:polymorphisms: :-509C>T (human)
CTD
RGD
PMID:15750822 PMID:17785866 RGD:4145294 NCBI chr 6:35,651,583...35,674,387
Ensembl chr 6:35,648,677...35,674,365
JBrowse link
G TNF tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:8428540 PMID:12449171 PMID:15127972 PMID:16980557
bird fancier's lung term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MUC1 mucin 1, cell surface associated ISO protein:increased expression:serum RGD PMID:15881280 RGD:5131172 NCBI chr20:8,641,701...8,646,739
Ensembl chr20:8,642,842...8,646,962
JBrowse link
childhood-onset asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NFKBIA NFKB inhibitor alpha exacerbates ISO associated with respiratory syncytial virus infectious disease;DNA:SNPs:protomer: (rs2233409) (human) RGD PMID:23487427 RGD:40902982 NCBI chr24:12,211,619...12,216,185
Ensembl chr24:12,210,281...12,214,854
JBrowse link
chronic asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NGF nerve growth factor treatment ISO RGD PMID:30681402 RGD:405100716 NCBI chr20:18,361,795...18,413,987
Ensembl chr20:18,413,108...18,413,833
JBrowse link
Eosinophilic Asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL26 C-C motif chemokine ligand 26 severity ISO protein:increased expression:sputum (human) RGD PMID:25936567 RGD:11531115 NCBI chr28:10,036,177...10,038,962
Ensembl chr28:10,036,337...10,038,875
JBrowse link
G EPX eosinophil peroxidase treatment ISO RGD PMID:28751233 RGD:13506890 NCBI chr16:35,196,433...35,208,269
Ensembl chr16:35,192,971...35,207,874
JBrowse link
exercise-induced bronchoconstriction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX5 arachidonate 5-lipoxygenase ISO RGD PMID:10984370 RGD:4890423 NCBI chr 9:41,085,257...41,145,760
Ensembl chr 9:41,085,361...41,145,331
JBrowse link
G CCL5 C-C motif chemokine ligand 5 ISO protein:increased secretion:lung, secretion (human) RGD PMID:19996575 RGD:4892021 NCBI chr16:29,351,214...29,361,317 JBrowse link
G TACR1 tachykinin receptor 1 ISO RGD PMID:8630576 RGD:5147837 NCBI chr14:32,080,319...32,236,556
Ensembl chr14:32,083,615...32,233,596
JBrowse link
Experimental Allergic Asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACSL3 acyl-CoA synthetase long chain family member 3 ISO RGD PMID:23526225 RGD:13831300 NCBI chr10:108,787,341...108,867,523
Ensembl chr10:108,787,061...108,869,042
JBrowse link
G BCL2 BCL2 apoptosis regulator treatment ISO RGD PMID:29713367 RGD:13792581 NCBI chr18:16,440,560...16,643,187
Ensembl chr18:16,441,733...16,637,895
JBrowse link
G CD86 CD86 molecule treatment ISO RGD PMID:25344652 RGD:11354965 NCBI chr22:58,741,534...58,805,417
Ensembl chr22:58,741,525...58,805,366
JBrowse link
G FASLG Fas ligand treatment ISO RGD PMID:29713367 RGD:13792581 NCBI chr25:56,488,572...56,496,469
Ensembl chr25:56,489,417...56,496,251
JBrowse link
G IL23A interleukin 23 subunit alpha ISO RGD PMID:19935773 PMID:26344076 RGD:11251537 RGD:5037240 NCBI chr11:52,289,486...52,296,735
Ensembl chr11:52,295,106...52,297,244
JBrowse link
extrinsic allergic alveolitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL5 C-C motif chemokine ligand 5 ISO protein:increased secretion:lung, secretion (mouse)
mRNA:increased expression:lung:bronchoalveolar lavage cell (human)
RGD PMID:10384061 PMID:16387809 RGD:4891434 RGD:4891436 NCBI chr16:29,351,214...29,361,317 JBrowse link
G CCL7 C-C motif chemokine ligand 7 ISO RGD PMID:20027288 RGD:5130978 NCBI chr16:27,777,795...27,780,413 JBrowse link
G CCR3 C-C motif chemokine receptor 3 ISO RGD PMID:19842835 RGD:4145620 NCBI chr22:7,648,410...7,698,523
Ensembl chr22:7,697,068...7,698,135
JBrowse link
G CD86 CD86 molecule ISO associated with Paramyxoviridae Infections; protein:increased expression:lung (mouse) RGD PMID:19282343 RGD:4892294 NCBI chr22:58,741,534...58,805,417
Ensembl chr22:58,741,525...58,805,366
JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 ISO mRNA:increased expression:alveolar macrophage RGD PMID:14991597 PMID:15725351 RGD:5135448 RGD:5135490 NCBI chr 7:24,526,657...24,529,193
Ensembl chr 7:24,526,680...24,529,130
JBrowse link
G CXCL11 C-X-C motif chemokine ligand 11 ISO RGD PMID:14991597 RGD:5135448 NCBI chr 7:24,540,401...24,543,456
Ensembl chr 7:24,541,767...24,542,832
JBrowse link
G CXCL9 C-X-C motif chemokine ligand 9 ISO mRNA:increased expression:alveolar macrophage RGD PMID:14991597 PMID:15725351 RGD:5135448 RGD:5135490 NCBI chr 7:24,507,121...24,513,830
Ensembl chr 7:24,507,130...24,513,121
JBrowse link
G CXCR3 C-X-C motif chemokine receptor 3 ISO RGD PMID:14991597 PMID:19842835 RGD:4145620 RGD:5135448 NCBI chr  X:61,430,723...61,433,777
Ensembl chr  X:61,430,725...61,433,386
JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO mRNA:decreased expression:leukocyte RGD PMID:20514434 RGD:4892076 NCBI chr26:53,390,054...53,403,309
Ensembl chr26:53,390,089...53,404,211
JBrowse link
G IL13 interleukin 13 ISO mRNA:increased expression:lung RGD PMID:9916735 PMID:20861649 RGD:4145650 RGD:5128548 NCBI chr23:35,475,762...35,479,419
Ensembl chr23:35,476,490...35,478,869
JBrowse link
G IL17A interleukin 17A ISO associated with Silicosis RGD PMID:19151189 PMID:20421647 RGD:4888525 RGD:4889106 NCBI chr17:20,314,082...20,319,917
Ensembl chr17:20,315,773...20,318,785
JBrowse link
G IL1A interleukin 1 alpha ISO protein:increased expression:Bronchoalveolar Lavage Fluid RGD PMID:10882225 RGD:4142832 NCBI chr14:15,789,710...15,801,938
Ensembl chr14:15,789,013...15,796,611
JBrowse link
G IL1B interleukin 1 beta disease_progression ISO protein:increased expression:serum (human) RGD PMID:1519663 PMID:19556641 RGD:4142842 RGD:7401229 NCBI chr14:15,844,628...15,852,652
Ensembl chr14:15,844,672...15,850,729
JBrowse link
G IL5 interleukin 5 ISO protein:increased expression:lung,respiratory system fluid/secretion RGD PMID:19151189 RGD:4889106 NCBI chr23:35,360,143...35,375,169
Ensembl chr23:35,360,506...35,362,178
JBrowse link
G NOS2 nitric oxide synthase 2 ISO protein:increased expression:lung RGD PMID:11789718 RGD:4891449 NCBI chr16:21,533,011...21,576,645
Ensembl chr16:21,533,484...21,574,257
JBrowse link
G SOD2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10673208 NCBI chr13:87,284,537...87,297,998
Ensembl chr13:87,280,686...87,297,974
JBrowse link
G TAP1 transporter 1, ATP binding cassette subfamily B member susceptibility ISO DNA:polymorphisms:cds:P. D637G, P661P (human) RGD PMID:18342853 RGD:5147840 NCBI chr17:39,252,000...39,260,195 JBrowse link
G TLR6 toll like receptor 6 ISO RGD PMID:20070409 RGD:4889532 NCBI chr27:11,439,288...11,461,580
Ensembl chr27:11,459,181...11,461,571
JBrowse link
G TNC tenascin C ISO protein:increased expression:respiratory system fluid/secretion RGD PMID:9780295 RGD:4889595 NCBI chr12:24,457,616...24,556,194
Ensembl chr12:24,457,738...24,556,451
JBrowse link
G TNF tumor necrosis factor ISO protein:increased expression:Bronchoalveolar Lavage Fluid RGD PMID:10882225 PMID:15653992 RGD:4142832 RGD:4143466
G TNFRSF1A TNF receptor superfamily member 1A ISO protein:increased expression:alveolar macrophage (human) RGD PMID:15929959 RGD:5131148 NCBI chr11:6,364,544...6,378,880
Ensembl chr11:6,364,330...6,378,902
JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B ISO protein:increased expression:alveolar macrophage (human) RGD PMID:15929959 RGD:5131148 NCBI chr20:119,590,621...119,633,562
Ensembl chr20:119,590,325...119,633,497
JBrowse link
G VEGFA vascular endothelial growth factor A ISO RGD PMID:15764076 RGD:5684419 NCBI chr17:28,377,959...28,394,508 JBrowse link
farmer's lung term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL12B interleukin 12B ISO RGD PMID:12084045 RGD:4145430 NCBI chr23:61,714,293...61,731,835 JBrowse link
G TNF tumor necrosis factor ISO DNA:polymorphism:promoter
protein:increased secretion:macrophage
RGD PMID:8466130 PMID:11179110 RGD:4143374 RGD:4143375
Ige Responsiveness, Atopic term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HAVCR1 hepatitis A virus cellular receptor 1 ISO ClinVar Annotator: match by term: IgE responsiveness, atopic ClinVar PMID:14534576 PMID:21339644 NCBI chr23:59,422,769...59,454,183
Ensembl chr23:59,423,334...59,453,531
JBrowse link
G IL17A interleukin 17A ISO associated with Nasal Polyps;protein:increased expression:nasal polyps (human) RGD PMID:24141678 RGD:9068428 NCBI chr17:20,314,082...20,319,917
Ensembl chr17:20,315,773...20,318,785
JBrowse link
G IL21R interleukin 21 receptor ISO ClinVar Annotator: match by term: IgE responsiveness, atopic | ClinVar Annotator: match by term: Ige, elevated level of ClinVar PMID:12700598 PMID:17015683 PMID:25741868 PMID:28492532 NCBI chr 5:25,105,947...25,153,914
Ensembl chr 5:25,106,519...25,153,703
JBrowse link
G IL4R interleukin 4 receptor ISO ClinVar Annotator: match by term: IgE responsiveness, atopic ClinVar PMID:25741868 PMID:28492532 NCBI chr 5:25,019,638...25,069,732
Ensembl chr 5:25,046,701...25,070,015
JBrowse link
occupational asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGER advanced glycosylation end-product specific receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:33075463 NCBI chr17:39,847,343...39,851,288
Ensembl chr17:39,847,759...39,851,127
JBrowse link
G CDH17 cadherin 17 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25918132 NCBI chr 8:89,101,788...89,179,353
Ensembl chr 8:89,101,744...89,179,251
JBrowse link
G HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25918132 NCBI chr26:53,760,172...54,007,356
Ensembl chr26:53,792,593...54,007,489
JBrowse link
G MHC-DOA major histocompatibility complex, class II, DO alpha treatment ISO DNA:SNP: :rs3128935(human) RGD PMID:24709764 RGD:13506912 NCBI chr17:39,084,785...39,090,477
Ensembl chr17:39,085,080...39,090,474
JBrowse link
G MHC-DPB1 major histocompatibility complex, class II, DP beta 1 susceptibility ISO DNA:SNP: : rs928976(human) RGD PMID:24709764 RGD:13506912 NCBI chr17:38,996,329...39,007,097 JBrowse link
G PLA2G4A phospholipase A2 group IVA ISO CTD Direct Evidence: marker/mechanism CTD PMID:27504716 NCBI chr25:42,443,480...42,590,895
Ensembl chr25:42,443,385...42,590,431
JBrowse link
G PRKCA protein kinase C alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:27504716 NCBI chr16:54,638,548...55,144,372
Ensembl chr16:54,642,729...54,948,256
JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25721048 NCBI chr12:17,195,403...17,218,450
Ensembl chr12:17,192,628...17,218,315
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25721048 NCBI chr25:42,733,535...42,742,463
Ensembl chr25:42,734,771...42,742,429
JBrowse link
G TENM3 teneurin transmembrane protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25918132 NCBI chr 7:127,231,840...128,792,832
Ensembl chr 7:128,598,835...128,795,211
JBrowse link
G TGFB1 transforming growth factor beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25721048 NCBI chr 6:35,651,583...35,674,387
Ensembl chr 6:35,648,677...35,674,365
JBrowse link
G TNF tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:25721048
Perennial Allergic Rhinitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOQ adiponectin, C1Q and collagen domain containing ISO protein:decreased expression:serum RGD PMID:19725899 RGD:5686851 NCBI chr15:81,128,427...81,142,779
Ensembl chr15:81,129,795...81,147,391
JBrowse link
G ALB albumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19389874 NCBI chr 7:21,872,036...21,890,095
Ensembl chr 7:21,876,132...21,891,407
JBrowse link
G ALOX5AP arachidonate 5-lipoxygenase activating protein ISO protein:increased expression:nasal turbinate RGD PMID:19364335 RGD:5147461 NCBI chr 3:9,618,030...9,642,990
Ensembl chr 3:9,617,949...9,643,184
JBrowse link
G CAT catalase ISO protein:decreased expression:plasma RGD PMID:20493834 RGD:5130771 NCBI chr 1:30,792,533...30,828,920
Ensembl chr 1:30,792,399...30,829,592
JBrowse link
G CCL2 C-C motif chemokine ligand 2 ISO protein:increased expression:nasal turbinate, mucosa (human) RGD PMID:9865755 RGD:8548839 NCBI chr16:27,763,354...27,765,437
Ensembl chr16:27,763,555...27,765,416
JBrowse link
G CCR2 C-C motif chemokine receptor 2 ISO mRNA:increased expression:Nasal Mucosa RGD PMID:17982926 RGD:4145109 NCBI chr22:7,795,192...7,801,242
Ensembl chr22:7,798,646...7,799,728
JBrowse link
G CCR5 C-C motif chemokine receptor 5 ISO mRNA:increased expression:nasal mucosa (human) RGD PMID:17982926 RGD:4145109 NCBI chr22:7,803,794...7,818,112 JBrowse link
G CD40 CD40 molecule ISO RGD PMID:20226305 RGD:5132269 NCBI chr 2:17,753,713...17,765,134
Ensembl chr 2:17,753,394...17,764,566
JBrowse link
G CD86 CD86 molecule ISO protein:increased expression:nasal mucosa, dendritic cell (human) RGD PMID:17088138 RGD:4892343 NCBI chr22:58,741,534...58,805,417
Ensembl chr22:58,741,525...58,805,366
JBrowse link
G EGR1 early growth response 1 ISO DNA:snp:5' utr:g.-4071A>G rs7729723 (human) RGD PMID:19833116 RGD:5131984 NCBI chr23:41,139,636...41,143,598
Ensembl chr23:41,140,065...41,142,374
JBrowse link
G F2RL1 F2R like trypsin receptor 1 ISO RGD PMID:17727088 RGD:4892590 NCBI chr 4:71,095,446...71,109,832
Ensembl chr 4:71,095,500...71,110,005
JBrowse link
G GSTP1 glutathione S-transferase pi 1 susceptibility ISO DNA:polymorphism:exon:p.I105V (rs1695) (human) RGD PMID:17181111 RGD:4142523 NCBI chr 1:6,676,897...6,679,936 JBrowse link
G HMOX1 heme oxygenase 1 ISO mRNA, protein:increased expression: nasal mucosa RGD PMID:16540907 RGD:4145406 NCBI chr19:18,144,466...18,157,944
Ensembl chr19:18,144,545...18,157,971
JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO protein:increased secretion:nasopharynx (human)
protein:increased expression:lung, endothelium (mouse)
RGD PMID:19047814 PMID:19968652 RGD:4145464 RGD:4145520 NCBI chr 6:9,320,991...9,338,125
Ensembl chr 6:9,322,550...9,338,263
JBrowse link
G IFNGR1 interferon gamma receptor 1 ISO DNA: SNP: Leu467Pro RGD PMID:12851715 RGD:6480431 NCBI chr13:36,203,038...36,224,039
Ensembl chr13:36,203,004...36,222,542
JBrowse link
G IL13 interleukin 13 ISO mRNA, protein:increased expression:nasal mucosa RGD PMID:8520776 RGD:4782826 NCBI chr23:35,475,762...35,479,419
Ensembl chr23:35,476,490...35,478,869
JBrowse link
G IL17A interleukin 17A severity ISO protein:increased expression:serum RGD PMID:19226302 RGD:4889151 NCBI chr17:20,314,082...20,319,917
Ensembl chr17:20,315,773...20,318,785
JBrowse link
G IL18 interleukin 18 susceptibility ISO DNA:SNP:promoter:c. -607A>C (rs1946518) (human) RGD PMID:16406079 RGD:4889924 NCBI chr 1:103,485,868...103,511,632
Ensembl chr 1:103,482,083...103,510,150
JBrowse link
G IL1A interleukin 1 alpha ISO DNA:polymorphism:exon:c.4845G>T (human) RGD PMID:14533660 RGD:4142859 NCBI chr14:15,789,710...15,801,938
Ensembl chr14:15,789,013...15,796,611
JBrowse link
G IL1R1 interleukin 1 receptor type 1 ISO RGD PMID:18637763 RGD:5037238 NCBI chr14:5,781,486...5,852,872
Ensembl chr14:5,781,479...5,855,942
JBrowse link
G IL2 interleukin 2 ISO protein:decreased expression:serum: RGD PMID:17608155 RGD:8662959 NCBI chr 7:69,729,635...69,736,279
Ensembl chr 7:69,730,282...69,734,969
JBrowse link
G IL4 interleukin 4 treatment ISO protein:increased expression:serum RGD PMID:9237816 PMID:15329007 PMID:21171297 RGD:5128559 RGD:7829804 RGD:7829817 NCBI chr23:35,492,158...35,501,349
Ensembl chr23:35,492,939...35,501,258
JBrowse link
G IL5 interleukin 5 ISO protein: increased levels: sputum RGD PMID:22186238 RGD:5687140 NCBI chr23:35,360,143...35,375,169
Ensembl chr23:35,360,506...35,362,178
JBrowse link
G LOC103233689 thromboxane A2 receptor treatment ISO RGD PMID:15247523 RGD:11059532 NCBI chr 6:3,354,358...3,365,779
Ensembl chr 6:3,355,314...3,359,761
JBrowse link
G MMP2 matrix metallopeptidase 2 ISO protein:increased expression:nasal mucosa: RGD PMID:19786210 RGD:5130872 NCBI chr 5:41,264,382...41,291,657
Ensembl chr 5:41,264,354...41,291,004
JBrowse link
G MMP9 matrix metallopeptidase 9 ISO protein:increased expression:nasal mucosa: RGD PMID:19786210 RGD:5130872 NCBI chr 2:17,867,267...17,874,757
Ensembl chr 2:17,867,177...17,874,712
JBrowse link
G NOS2 nitric oxide synthase 2 ISO protein:increased expression:nasal mucosa RGD PMID:14587983 RGD:4892078 NCBI chr16:21,533,011...21,576,645
Ensembl chr16:21,533,484...21,574,257
JBrowse link
G NOS3 nitric oxide synthase 3 ISO DNA:snp:promoter:g.-786T>C (human) RGD PMID:18086269 RGD:4892054 NCBI chr21:119,174,829...119,196,840 JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 ISO protein:altered expression:nasal mucosa RGD PMID:20185258 RGD:4892593 NCBI chr23:45,904,926...46,031,804
Ensembl chr23:45,904,873...46,031,125
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma ISO mRNA, protein:increased expression:nasal mucosa (human) RGD PMID:17116814 RGD:8552811 NCBI chr22:48,262,743...48,407,415
Ensembl chr22:48,275,600...48,407,418
JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO protein:increased expression:respiratory system epithelium RGD PMID:19364335 RGD:5147461 NCBI chr12:17,195,403...17,218,450
Ensembl chr12:17,192,628...17,218,315
JBrowse link
Platelet-Activating Factor Acetylhydrolase Deficiency term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLA2G7 phospholipase A2 group VII ISO ClinVar Annotator: match by term: Platelet-activating factor acetylhydrolase deficiency ClinVar
OMIM
PMID:8675689 PMID:9412624 PMID:10194471 PMID:10733466 PMID:16787988 More... NCBI chr17:25,538,645...25,571,230
Ensembl chr17:25,538,438...25,574,269
JBrowse link
Seasonal Allergic Rhinitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX5 arachidonate 5-lipoxygenase ISO RGD PMID:16677242 RGD:5147463 NCBI chr 9:41,085,257...41,145,760
Ensembl chr 9:41,085,361...41,145,331
JBrowse link
G APOA4 apolipoprotein A4 resistance ISO protein:increased expression:blood serum (human) RGD PMID:20810159 RGD:5685642 NCBI chr 1:108,186,627...108,190,508
Ensembl chr 1:108,186,921...108,189,698
JBrowse link
G BDNF brain derived neurotrophic factor severity ISO protein:increased expression:blood, nasal cavity epithelium RGD PMID:18266897 RGD:5144117 NCBI chr 1:37,386,825...37,451,380
Ensembl chr 1:37,449,593...37,450,336
JBrowse link
G CCL5 C-C motif chemokine ligand 5 ISO protein:increased expression:inferior turbinate, epithelium (human) RGD PMID:20459697 RGD:4891379 NCBI chr16:29,351,214...29,361,317 JBrowse link
G CMA1 chymase 1 ISO protein:increased expression:nasal mucosa, mast cell (human) RGD PMID:11549546 RGD:5128839 NCBI chr24:1,471,767...1,475,062
Ensembl chr24:1,471,725...1,474,692
JBrowse link
G FGA fibrinogen alpha chain ISO RGD PMID:21887273 RGD:5688767 NCBI chr 7:101,127,554...101,134,881
Ensembl chr 7:101,125,791...101,134,405
JBrowse link
G GSTO1 glutathione S-transferase omega 1 ISO protein:decreased expression;T lymphocyte: RGD PMID:21410266 RGD:5491008 NCBI chr 9:97,305,094...97,317,892 JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO protein:increased secretion:nasopharynx, secretion (human) RGD PMID:20128420 RGD:4145459 NCBI chr 6:9,320,991...9,338,125
Ensembl chr 6:9,322,550...9,338,263
JBrowse link
G IFNGR1 interferon gamma receptor 1 ISO DNA: SNP: Leu467Pro RGD PMID:12851715 RGD:6480431 NCBI chr13:36,203,038...36,224,039
Ensembl chr13:36,203,004...36,222,542
JBrowse link
G IL10 interleukin 10 treatment ISO RGD PMID:19505388 RGD:7365025 NCBI chr25:22,590,389...22,595,877
Ensembl chr25:22,590,962...22,594,836
JBrowse link
G IL18 interleukin 18 no_association
susceptibility
ISO DNA:SNPs:promoters:multiple
DNA:SNPs:promoters, exon:multiple
RGD PMID:12532106 RGD:8655871 NCBI chr 1:103,485,868...103,511,632
Ensembl chr 1:103,482,083...103,510,150
JBrowse link
G IL4 interleukin 4 ISO protein:increased expression:serum
mRNA:increased expression:nose:
RGD PMID:7551298 PMID:9237816 RGD:7829817 RGD:8662960 NCBI chr23:35,492,158...35,501,349
Ensembl chr23:35,492,939...35,501,258
JBrowse link
G KDR kinase insert domain receptor ISO protein:increased expression:nasal cavity of mucosa: RGD PMID:17651148 RGD:8551771 NCBI chr 7:13,435,059...13,482,236
Ensembl chr 7:13,435,096...13,482,771
JBrowse link
G MMP9 matrix metallopeptidase 9 ISO DNA:SNPs:promoter, intron, cds:-1590C>T, 2127G>T, p.R668Q (rs3918242, rs2274755, rs17577) (human) RGD PMID:22237587 RGD:8547819 NCBI chr 2:17,867,267...17,874,757
Ensembl chr 2:17,867,177...17,874,712
JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 susceptibility ISO DNA:SNP: :rs2075817 (human) RGD PMID:16918516 RGD:5131519 NCBI chr21:27,907,628...27,957,621
Ensembl chr21:27,926,710...27,957,619
JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 susceptibility ISO DNA:polymorphisms:5'UTR/exon, exon:rs5743266, rs2066842 (human) RGD PMID:16008671 RGD:5131477 NCBI chr 5:36,492,158...36,531,766
Ensembl chr 5:36,496,414...36,530,499
JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO protein:increased expression:respiratory system epithelium RGD PMID:19364335 RGD:5147461 NCBI chr12:17,195,403...17,218,450
Ensembl chr12:17,192,628...17,218,315
JBrowse link
G SCGB1A1 secretoglobin family 1A member 1 ISO mRNA, protein:decreased expression:nasal lavage fluid RGD PMID:15836756 RGD:5144234 NCBI chr 1:11,470,091...11,474,915
Ensembl chr 1:11,470,195...11,474,149
JBrowse link
G TLR3 toll like receptor 3 ISO protein:decreased expression:bone marrow, blood, eosinophil (human) RGD PMID:19752565 RGD:5129130 NCBI chr 7:131,991,068...132,014,366
Ensembl chr 7:131,991,029...132,016,232
JBrowse link
G TLR4 toll like receptor 4 susceptibility ISO DNA:polymorphisms:cds:p.D299G, T399I (human) RGD PMID:18517079 RGD:4144192 NCBI chr12:21,873,762...21,885,562
Ensembl chr12:21,871,773...21,885,515
JBrowse link
G VEGFA vascular endothelial growth factor A ISO mRNA,protein:increased expression:nasal biopsies,nasal lavage fluid: RGD PMID:12633568 RGD:7483595 NCBI chr17:28,377,959...28,394,508 JBrowse link
sick building syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PNPLA6 patatin like phospholipase domain containing 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23418070 NCBI chr 6:7,030,802...7,056,664
Ensembl chr 6:7,032,445...7,056,661
JBrowse link
status asthmaticus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFNG interferon gamma resistance ISO RGD PMID:20817868 RGD:4145651 NCBI chr11:63,785,493...63,791,071
Ensembl chr11:63,786,041...63,790,473
JBrowse link
G IL1B interleukin 1 beta ISO protein:increased expression:lung RGD PMID:9927362 RGD:4143184 NCBI chr14:15,844,628...15,852,652
Ensembl chr14:15,844,672...15,850,729
JBrowse link
G IL5 interleukin 5 ISO protein:increased expression:respiratory system fluid/secretion RGD PMID:10934091 RGD:4890960 NCBI chr23:35,360,143...35,375,169
Ensembl chr23:35,360,506...35,362,178
JBrowse link
G MPO myeloperoxidase ISO protein:increased expression:serum RGD PMID:10731862 RGD:5130994 NCBI chr16:35,120,194...35,130,851
Ensembl chr16:35,120,581...35,130,671
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15342
    disease of anatomical entity 15027
      respiratory system disease 4764
        respiratory allergy 370
          4-vinylcyclohexene dioxide respiratory allergy 0
          Allergic Rhinosinusitis + 0
          Formaldehyde Poisoning 0
          Ige Responsiveness, Atopic 4
          acid anhydride respiratory allergy 0
          allergic asthma + 12
          allergic bronchopulmonary aspergillosis 9
          allergic rhinitis + 76
          asthma + 336
          berylliosis 9
          chloramine T respiratory allergy 0
          extrinsic allergic alveolitis + 26
          remazole black respiratory allergy 0
Path 2
Term Annotations click to browse term
  disease 15342
    disease of anatomical entity 15027
      Immune & Inflammatory Diseases 5118
        immune system disease 4454
          allergic disease 585
            Immediate Hypersensitivity 446
              respiratory allergy 370
                4-vinylcyclohexene dioxide respiratory allergy 0
                Allergic Rhinosinusitis + 0
                Formaldehyde Poisoning 0
                Ige Responsiveness, Atopic 4
                acid anhydride respiratory allergy 0
                allergic asthma + 12
                allergic bronchopulmonary aspergillosis 9
                allergic rhinitis + 76
                asthma + 336
                berylliosis 9
                chloramine T respiratory allergy 0
                extrinsic allergic alveolitis + 26
                remazole black respiratory allergy 0
paths to the root