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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:chemical colitis
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Accession:DOID:0060186 term browser browse the term
Definition:A colitis caused_by introduction of various chemicals. (DO)
Synonyms:xref: ICD10CM:K52;   ICD9CM:558


show annotations for term's descendants           Sort by:
chemical colitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme ISO protein:increased expression:small intestine, large intestine:extracellular space (mouse) RGD PMID:26401072 RGD:11555935 NCBI chr10:91,410,129...91,430,246
Ensembl chr10:91,409,819...91,430,942 		JBrowse link
G Ace2 angiotensin converting enzyme 2 severity ISO Ace2 knockout
Ace2 inhibitor 		RGD PMID:22837003 PMID:19517214 RGD:40818307, RGD:40818410 NCBI chr  X:33,925,458...33,972,851
Ensembl chr  X:33,925,458...33,971,596 		JBrowse link
G Casp3 caspase 3 treatment ISO RGD PMID:28740344 RGD:13782278 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp7 caspase 7 treatment ISO RGD PMID:28740344 RGD:13782278 NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512 		JBrowse link
G Serpina1 serpin family A member 1 treatment ISO RGD PMID:23835442 RGD:14695050 NCBI chr 6:128,631,101...128,653,125
Ensembl chr 6:128,619,382...128,660,703 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19150
    disease of anatomical entity 18458
      gastrointestinal system disease 7218
        intestinal disease 3129
          inflammatory bowel disease 488
            colitis 258
              chemical colitis 5
Path 2
Term Annotations click to browse term
  disease 19150
    Pathological Conditions, Signs and Symptoms 13669
      Pathologic Processes 8404
        Inflammation 2848
          gastroenteritis 571
            inflammatory bowel disease 488
              colitis 258
                chemical colitis 5
paths to the root