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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:colitis
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Accession:DOID:0060180 term browser browse the term
Definition:An inflammatory bowel disease that involves inflammation located_in colon. (DO)
Synonyms:exact_synonym: colitides
 primary_id: MESH:D003092
 xref: EFO:0003872;   NCI:C26723


show annotations for term's descendants           Sort by:
colitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM17 ADAM metallopeptidase domain 17 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24548422 NCBI chr 3:126,795,513...126,853,995
Ensembl chr 3:126,795,426...126,853,995 		JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing ISO RGD PMID:17604368 PMID:21479819 RGD:5686754 RGD:5686898 NCBI chr13:124,633,906...124,646,237
Ensembl chr13:124,633,685...124,646,646 		JBrowse link
G ADK adenosine kinase ISO RGD PMID:11123368 RGD:6482664 NCBI chr14:76,836,072...77,320,586
Ensembl chr14:76,836,095...77,322,416 		JBrowse link
G ADRB3 adrenoceptor beta 3 ISO mRNA:decreased expression:distal colon, mucosa (rat) RGD PMID:18492028 RGD:5684890 NCBI chr15:48,468,803...48,478,370
Ensembl chr15:48,475,144...48,479,562 		JBrowse link
G AHR aryl hydrocarbon receptor ISO CTD Direct Evidence: therapeutic CTD PMID:27783946 NCBI chr 9:86,511,866...86,555,950
Ensembl chr 9:86,511,369...86,555,943 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:15821759 NCBI chr14:90,859,209...90,907,084
Ensembl chr14:90,859,019...90,907,090 		JBrowse link
G ANXA1 annexin A1 ISO protein:increased expression:colon, neutrophil RGD PMID:10489933 RGD:2306920 NCBI chr 1:226,414,200...226,431,963
Ensembl chr 1:226,414,306...226,432,279 		JBrowse link
G APLN apelin ISO RGD PMID:17391779 RGD:1626177 NCBI chr  X:106,236,746...106,246,563
Ensembl chr  X:106,236,749...106,246,377 		JBrowse link
G APOA4 apolipoprotein A4 ISO human protein in mouse model RGD PMID:15254593 RGD:5685667 NCBI chr 9:44,201,587...44,204,072
Ensembl chr 9:44,201,508...44,204,206 		JBrowse link
G AQP7 aquaporin 7 ISO associated with Infection;mRNA, protein:decreased expression:colon RGD PMID:15338270 RGD:1626292 NCBI chr10:33,098,746...33,130,245 JBrowse link
G ARG1 arginase 1 severity ISO RGD PMID:28423665 RGD:39939041 NCBI chr 1:32,006,035...32,028,983
Ensembl chr 1:32,006,046...32,028,988 		JBrowse link
G ARRB1 arrestin beta 1 ISO protein:increased expression:colon (rat) RGD PMID:21066892 RGD:5509893 NCBI chr 9:9,516,944...9,597,446
Ensembl chr 9:9,516,947...9,597,976 		JBrowse link
G ATP5F1D ATP synthase F1 subunit delta treatment ISO RGD PMID:23840258 RGD:13792680 NCBI chr 2:77,216,430...77,219,301
Ensembl chr 2:77,216,436...77,222,632 		JBrowse link
G BDNF brain derived neurotrophic factor ISO protein:increased expression:dorsal root ganglion: RGD PMID:19932037 RGD:8657331 NCBI chr 2:32,623,668...32,679,293
Ensembl chr 2:32,624,048...32,679,765 		JBrowse link
G BMP6 bone morphogenetic protein 6 ISO RGD PMID:22361727 RGD:7242194 NCBI chr 7:5,058,817...5,208,868
Ensembl chr 7:5,058,817...5,210,270 		JBrowse link
G BTK Bruton tyrosine kinase ameliorates ISO Associated with candidiasis RGD PMID:25379804 RGD:124713568 NCBI chr  X:82,981,512...83,014,475
Ensembl chr  X:82,981,515...83,014,573 		JBrowse link
G CA1 carbonic anhydrase 1 ISO protein:decreased expression:urine RGD PMID:31095872 RGD:408427353 NCBI chr 4:51,343,548...51,353,127
Ensembl chr 4:51,302,406...51,353,126 		JBrowse link
G CAT catalase ISO RGD PMID:21463646 RGD:5130869 NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452 		JBrowse link
G CCKBR cholecystokinin B receptor ISO RGD PMID:15102523 RGD:2311333 NCBI chr 9:3,409,222...3,419,513 JBrowse link
G CCL2 chemokine (C-C motif) ligand 2 ISO RGD PMID:18690297 RGD:2307009 NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,026 		JBrowse link
G CCR1 C-C motif chemokine receptor 1 ISO RGD PMID:16399111 RGD:2307162 NCBI chr13:29,227,218...29,233,862
Ensembl chr13:29,227,222...29,233,960 		JBrowse link
G CD36 CD36 molecule ISO RGD PMID:19117124 RGD:6893503 NCBI chr 9:99,685,748...99,782,296
Ensembl chr 9:99,605,181...99,782,105 		JBrowse link
G CD40 CD40 molecule ISO RGD PMID:15591506 RGD:5508169 NCBI chr17:48,286,116...48,298,188
Ensembl chr17:48,286,029...48,298,528 		JBrowse link
G CHEK2 checkpoint kinase 2 ISO ClinVar Annotator: match by term: Colitis ClinVar PMID:10617473 PMID:11053450 PMID:11479205 PMID:11719428 PMID:11967536 More... NCBI chr14:45,699,833...45,967,350
Ensembl chr14:45,929,715...45,967,290 		JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex treatment ISO RGD PMID:17543437 RGD:2298659 NCBI chr14:111,316,178...111,351,669
Ensembl chr14:111,315,141...111,351,868 		JBrowse link
G CIITA class II major histocompatibility complex transactivator severity ISO protein:increased expression:T cells:constitutive expression of transgene increases severity
ClinVar Annotator: match by term: Colitis		 RGD
ClinVar		 PMID:17043423 PMID:25741868 PMID:28492532 RGD:5491188 NCBI chr 3:32,171,706...32,230,775
Ensembl chr 3:32,172,214...32,230,780 		JBrowse link
G CRHR2 corticotropin releasing hormone receptor 2 ISO mRNA, protein:decreased expression:intestine, myenteric nerve plexus RGD PMID:17586086 PMID:21330446 RGD:5131259 RGD:5490987 NCBI chr18:42,251,755...42,296,457
Ensembl chr18:42,251,749...42,295,467 		JBrowse link
G CTSB cathepsin B ISO protein:increased activity:cecum, colon, spinal cord RGD PMID:21802389 RGD:5686873 NCBI chr14:15,014,139...15,035,081
Ensembl chr14:15,011,711...15,033,877 		JBrowse link
G CTSL cathepsin L ISO protein:increased activity:cecum, colon, spinal cord RGD PMID:21802389 RGD:5686873 NCBI chr10:27,668,523...27,674,705
Ensembl chr10:27,668,264...27,674,618 		JBrowse link
G CTSS cathepsin S ISO protein:increased activity:cecum, colon, spinal cord RGD PMID:21802389 RGD:5686873 NCBI chr 4:98,415,273...98,442,952
Ensembl chr 4:98,417,883...98,442,950 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 ISO associated with Helicobacter Infections;mRNA:decreased expression:colon (mouse, Helicobacter hepaticus) RGD PMID:17242461 RGD:38549339 NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861 		JBrowse link
G CXCR2 C-X-C motif chemokine receptor 2 ISO RGD PMID:14738862 RGD:7257706 NCBI chr15:120,219,657...120,230,203 JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO mRNA:increased expression:large intestine epithelium RGD PMID:21374063 RGD:5147670 NCBI chr 7:58,802,887...58,809,155
Ensembl chr 7:58,802,887...58,809,775 		JBrowse link
G DUSP1 dual specificity phosphatase 1 severity ISO RGD PMID:22461024 RGD:7771532 NCBI chr16:51,457,924...51,461,095
Ensembl chr16:51,458,020...51,461,086 		JBrowse link
G ESR2 estrogen receptor 2 ISO mRNA:decreased expression:colon RGD PMID:21252046 RGD:5508810 NCBI chr 1:193,823,666...193,907,330
Ensembl chr 1:193,829,560...193,906,565 		JBrowse link
G FGF19 fibroblast growth factor 19 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27580383 NCBI chr 2:3,583,027...3,586,985
Ensembl chr 2:3,582,828...3,587,752 		JBrowse link
G FLNA filamin A ISO ClinVar Annotator: match by term: Colitis ClinVar PMID:25741868 PMID:28492532 PMID:30755392 NCBI chr  X:124,889,934...124,915,000
Ensembl chr  X:124,890,162...124,914,992 		JBrowse link
G GCG glucagon ISO CTD Direct Evidence: therapeutic CTD PMID:22323126 NCBI chr15:68,800,557...68,810,268
Ensembl chr15:68,800,560...68,810,242 		JBrowse link
G GHRL ghrelin and obestatin prepropeptide ISO CTD Direct Evidence: therapeutic CTD PMID:19617644 NCBI chr13:66,442,106...66,453,576
Ensembl chr13:66,445,992...66,452,917 		JBrowse link
G HAVCR1 hepatitis A virus cellular receptor 1 ISO mRNA:increased expression:kidney: RGD PMID:23307618 RGD:7245473 NCBI chr16:66,162,318...66,208,868 JBrowse link
G HMOX1 heme oxygenase 1 treatment ISO protein:increased expression:colon:
CTD Direct Evidence: therapeutic		 RGD
CTD		 PMID:16365149 PMID:21444764 PMID:21853095 PMID:22261574 RGD:10766442 RGD:7207796
G HP haptoglobin treatment ISO RGD PMID:22457771 RGD:11041866 NCBI chr 6:14,980,382...14,985,245 JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO protein:increased expression:colon: RGD PMID:22261574 RGD:7207796 NCBI chr 2:69,097,136...69,107,722
Ensembl chr 2:69,097,122...69,108,205 		JBrowse link
G ICOS inducible T cell costimulator ISO protein:increased expression:T-cell RGD PMID:14731127 RGD:1624274 NCBI chr15:107,350,253...107,370,123
Ensembl chr15:107,350,203...107,370,119 		JBrowse link
G IFNG interferon gamma ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:16717119 PMID:24548422 RGD:150573704 NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,906...32,482,670 		JBrowse link
G IGF1 insulin like growth factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24782617 NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,033 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta treatment ISO RGD PMID:17543437 RGD:2298659 NCBI chr17:11,289,607...11,348,557
Ensembl chr17:11,289,690...11,348,549 		JBrowse link
G IL10 interleukin 10 treatment ISO CTD Direct Evidence: marker/mechanism|therapeutic RGD
CTD		 PMID:19238344 PMID:21807089 PMID:21949848 PMID:22119709 PMID:22461024 More... RGD:7349385 RGD:7365024 RGD:7771532 NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,728...67,405,378 		JBrowse link
G IL17A interleukin 17A ISO mRNA:increased expression:colon
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:14962796 PMID:20881082 PMID:24548422 RGD:4781448 RGD:4888509 NCBI chr 7:46,013,584...46,017,161
Ensembl chr 7:46,013,584...46,017,153 		JBrowse link
G IL1RL1 interleukin 1 receptor like 1 severity ISO RGD PMID:23172891 RGD:40400694 NCBI chr 3:51,868,549...51,902,454
Ensembl chr 3:51,846,792...51,951,383 		JBrowse link
G IL33 interleukin 33 severity ISO RGD PMID:23172891 PMID:28423665 RGD:39939041 RGD:40400694 NCBI chr 1:215,899,830...215,941,944
Ensembl chr 1:215,899,436...215,941,840 		JBrowse link
G IL4 interleukin 4 treatment ISO CTD Direct Evidence: therapeutic RGD
CTD		 PMID:9389741 PMID:24314293 RGD:8142400 NCBI chr 2:134,986,817...134,994,365
Ensembl chr 2:134,986,817...134,994,365 		JBrowse link
G IL5 interleukin 5 ISO protein: increased expression RGD PMID:22018693 RGD:5687148 NCBI chr 2:134,832,143...134,846,141
Ensembl chr 2:134,832,147...134,835,212 		JBrowse link
G IL6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22410118 PMID:24548422 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263 		JBrowse link
G ITGB2 integrin subunit beta 2 ISO associated with Spirochaetales infections RGD PMID:11031123 RGD:6482227 NCBI chr13:207,514,281...207,544,108
Ensembl chr13:207,512,950...207,544,107 		JBrowse link
G KDR kinase insert domain receptor ISO protein:increased expression:colon: RGD PMID:22261574 RGD:7207796 NCBI chr 8:41,809,116...41,856,379
Ensembl chr 8:41,809,122...41,856,336 		JBrowse link
G LOC100625897 lactase-phlorizin hydrolase ISO protein:decreased expression, increased expression:jejunum RGD PMID:17218984 RGD:1600240 NCBI chr15:16,094,277...16,154,467 JBrowse link
G LOC110258578 interleukin-1 beta-like ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:22969190 PMID:23810507 PMID:24548422 RGD:7204699
G LRRK2 leucine rich repeat kinase 2 ISO RGD PMID:21983832 RGD:5508401 NCBI chr 5:71,800,337...71,945,828
Ensembl chr 5:71,800,225...71,945,828 		JBrowse link
G MADCAM1 mucosal vascular addressin cell adhesion molecule 1 ISO CTD Direct Evidence: therapeutic CTD PMID:16917232 NCBI chr 2:77,784,610...77,789,036
Ensembl chr 2:77,784,612...77,789,067 		JBrowse link
G MC1R melanocortin 1 receptor ISO RGD PMID:16543288 RGD:5687320 NCBI chr 6:181,225...182,187
Ensembl chr 6:181,225...182,187 		JBrowse link
G MIF macrophage migration inhibitory factor ISO CTD Direct Evidence: therapeutic RGD
CTD		 PMID:12105854 PMID:17324399 RGD:1641979 NCBI chr14:49,840,303...49,841,063
Ensembl chr14:49,840,305...49,841,068 		JBrowse link
G MIR150-1 microRNA mir-150-1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26937033 NCBI chr 6:54,580,912...54,580,988
Ensembl chr 6:54,580,912...54,580,988 		JBrowse link
G MPO myeloperoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23810507 NCBI chr12:34,557,031...34,570,091
Ensembl chr12:34,556,408...34,567,904 		JBrowse link
G MSH2 mutS homolog 2 ISO RGD PMID:23883737 RGD:10412318 NCBI chr 3:93,082,958...93,163,556
Ensembl chr 3:93,081,219...93,163,585 		JBrowse link
G MUC2 mucin 2, oligomeric mucus/gel-forming treatment ISO mRNA:decreased expression:colon
protein:decreased sulfation:descending colon		 RGD PMID:12395902 PMID:19220658 PMID:21949848 PMID:23395625 RGD:2324675 RGD:7349356 RGD:7349360 RGD:7349385 NCBI chr 2:689,363...719,542
Ensembl chr 2:689,364...710,330 		JBrowse link
G NAMPT nicotinamide phosphoribosyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23810507 NCBI chr 9:106,119,896...106,162,126
Ensembl chr 9:106,119,899...106,294,586 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 treatment ISO RGD PMID:30142311 RGD:42724458 NCBI chr15:82,967,485...83,146,185
Ensembl chr15:82,973,656...83,146,183 		JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 ISO RGD PMID:20921147 RGD:5508755 NCBI chr18:42,464,667...42,509,135
Ensembl chr18:42,432,050...42,512,264 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 ISO mRNA:increased expression:colon RGD PMID:16891783 PMID:20921147 PMID:21471573 RGD:1600781 RGD:5508727 RGD:5508755 NCBI chr 6:34,132,127...34,167,446
Ensembl chr 6:34,130,938...34,177,534 		JBrowse link
G NOS2 nitric oxide synthase 2 ISO mRNA:increased expression:colon
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:colon (mouse)		 RGD
CTD		 PMID:8698225 PMID:16866779 PMID:17449036 PMID:21930116 RGD:4891411 RGD:5509045 NCBI chr12:44,174,944...44,219,875
Ensembl chr12:44,174,948...44,218,146 		JBrowse link
G NOS3 nitric oxide synthase 3 ISO mRNA:increased expression:colon RGD PMID:17947450 RGD:2292124 NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,158...6,228,943 		JBrowse link
G NTRK1 neurotrophic receptor tyrosine kinase 1 ISO mRNA, protein:increased expression:neuron RGD PMID:20638179 RGD:5684542 NCBI chr 4:93,219,509...93,237,944
Ensembl chr 4:93,219,516...93,255,981 		JBrowse link
G NTRK2 neurotrophic receptor tyrosine kinase 2 ISO mRNA, protein:increased expression:dorsal root ganglion RGD PMID:20638179 RGD:5684542 NCBI chr10:30,030,050...30,429,938
Ensembl chr10:30,033,405...30,429,882 		JBrowse link
G PGF placental growth factor ISO RGD PMID:20142801 RGD:6483587 NCBI chr 7:98,149,510...98,162,784
Ensembl chr 7:98,148,994...98,162,741 		JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO RGD PMID:21244371 RGD:6482682 NCBI chr 9:106,698,200...106,748,217
Ensembl chr 9:106,698,207...106,745,099 		JBrowse link
G PLA2G2A phospholipase A2 group IIA ISO RGD PMID:17982090 RGD:6482729 NCBI chr 6:78,327,728...78,339,546
Ensembl chr 6:78,327,319...78,330,699 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha susceptibility ISO RGD PMID:20650341 RGD:5509936 NCBI chr 5:3,302,755...3,321,091
Ensembl chr 5:3,300,741...3,364,239 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha ISO RGD PMID:22126533 RGD:6484264 NCBI chr 8:17,841,844...18,527,953
Ensembl chr 8:17,841,844...17,946,992 		JBrowse link
G PTGER4 prostaglandin E receptor 4 ISO RGD PMID:20833794 RGD:6483551 NCBI chr16:25,670,832...25,686,556
Ensembl chr16:25,670,862...25,686,552 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:11820457 PMID:17543437 RGD:2298659 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit ISO protein:increased expression:nucleus
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:18623154 PMID:23810507 RGD:2298776 NCBI chr 2:6,594,869...6,602,684
Ensembl chr 2:6,593,969...6,603,469 		JBrowse link
G REN renin treatment ISO RGD PMID:24858618 RGD:125097500 NCBI chr 9:64,809,143...64,822,605
Ensembl chr 9:64,809,146...64,822,658 		JBrowse link
G RETN resistin treatment ISO RGD PMID:22630819 RGD:7207222 NCBI chr 2:71,484,164...71,485,577
Ensembl chr 2:71,484,169...71,485,616 		JBrowse link
G SELL selectin L ISO RGD PMID:18054560 RGD:5685703 NCBI chr 4:81,306,363...81,325,296
Ensembl chr 4:81,306,353...81,326,444 		JBrowse link
G SELP selectin P ISO protein:increased expression:colon RGD PMID:19147805 RGD:2312310 NCBI chr 4:81,376,804...81,401,240
Ensembl chr 4:81,365,740...81,399,955 		JBrowse link
G SELPLG selectin P ligand ISO RGD PMID:22009715 RGD:6218987 NCBI chr14:42,158,694...42,178,044 JBrowse link
G SI sucrase-isomaltase ISO mRNA, protein:decreased expression:ileum RGD PMID:16964428 RGD:1625545 NCBI chr13:104,296,281...104,379,558
Ensembl chr13:104,296,283...104,379,478 		JBrowse link
G SIRT1 sirtuin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19940103 PMID:24548422 PMID:24782617 NCBI chr14:71,091,167...71,126,351
Ensembl chr14:71,091,167...71,123,297 		JBrowse link
G SLC11A1 solute carrier family 11 member 1 ISO RGD PMID:19016783 RGD:5684975 NCBI chr15:120,434,100...120,446,396
Ensembl chr15:120,433,952...120,446,396 		JBrowse link
G SOCS1 suppressor of cytokine signaling 1 ISO RGD PMID:16717119 RGD:150573704 NCBI chr 3:31,879,143...31,883,041
Ensembl chr 3:31,881,225...31,884,967 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17551092 NCBI chr17:40,470,970...40,524,862
Ensembl chr17:40,471,009...40,524,860 		JBrowse link
G SYK spleen associated tyrosine kinase ISO ClinVar Annotator: match by term: Colitis ClinVar PMID:25741868 PMID:28492532 PMID:33782605 NCBI chr14:2,103,706...2,160,886
Ensembl chr14:2,056,670...2,161,171 		JBrowse link
G TAC1 tachykinin precursor 1 ISO RGD PMID:18715640 RGD:2304260 NCBI chr 9:77,197,403...77,206,529
Ensembl chr 9:77,197,536...77,206,523 		JBrowse link
G TACR1 tachykinin receptor 1 ISO RGD PMID:18715640 RGD:2304260 NCBI chr 3:67,839,367...68,021,733
Ensembl chr 3:67,839,411...68,021,724 		JBrowse link
G TACR2 tachykinin receptor 2 ISO RGD PMID:12490601 PMID:18715640 RGD:2304260 RGD:5147478 NCBI chr14:72,463,405...72,476,034
Ensembl chr14:72,462,046...72,475,554 		JBrowse link
G TES testin LIM domain protein ISO CTD Direct Evidence: therapeutic CTD PMID:39237074 NCBI chr18:29,895,878...29,936,248
Ensembl chr18:29,895,882...29,936,233 		JBrowse link
G TFF1 trefoil factor 1 ISO RGD PMID:8836141 RGD:625375 NCBI chr13:205,687,558...205,691,512
Ensembl chr13:205,687,560...205,691,460 		JBrowse link
G TIMP3 TIMP metallopeptidase inhibitor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24548422 NCBI chr 5:12,185,816...12,242,599
Ensembl chr 5:12,185,818...12,242,581 		JBrowse link
G TLR3 toll like receptor 3 ISO mRNA:increased expression:large intestine mucosa (rat) RGD PMID:20011045 RGD:5128708 NCBI chr15:46,966,262...46,977,774
Ensembl chr15:46,969,006...46,979,291 		JBrowse link
G TLR4 toll like receptor 4 ISO protein:increased expression:colon RGD PMID:19002562 PMID:19924809 RGD:2312573 RGD:7794773 NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,058,970 		JBrowse link
G TNF tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:23810507 PMID:24548422 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,415 		JBrowse link
G TREM1 triggering receptor expressed on myeloid cells 1 severity ISO RGD PMID:24453980 RGD:126925972 NCBI chr 7:36,510,253...36,531,796
Ensembl chr 7:36,510,253...36,531,796 		JBrowse link
G TST thiosulfate sulfurtransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19647029 NCBI chr 5:10,749,264...10,759,623
Ensembl chr 5:10,746,890...10,759,622 		JBrowse link
G UCN urocortin ISO mRNA:altered expression:distal colon (rat) RGD PMID:21330446 RGD:5490987 NCBI chr 3:111,834,082...111,835,932
Ensembl chr 3:111,835,125...111,835,508 		JBrowse link
G UCN2 urocortin 2 ISO mRNA:increased expression:colon (rat) RGD PMID:17586086 RGD:5131259 NCBI chr13:31,261,196...31,261,824
Ensembl chr13:31,261,196...31,261,534 		JBrowse link
G VCAM1 vascular cell adhesion molecule 1 ISO protein:increased expression:colon: RGD PMID:22261574 RGD:7207796 NCBI chr 4:117,496,914...117,511,211
Ensembl chr 4:117,496,920...117,511,222 		JBrowse link
G VIP vasoactive intestinal peptide ISO associated with Gram-Negative Bacterial Infections RGD PMID:19661153 RGD:5685605 NCBI chr 1:13,611,786...13,620,250
Ensembl chr 1:13,611,311...13,620,269 		JBrowse link
G VIPR2 vasoactive intestinal peptide receptor 2 ISO RGD PMID:21295288 RGD:5685384 NCBI chr18:396,379...466,408
Ensembl chr18:396,263...518,102 		JBrowse link
chemical colitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme ISO protein:increased expression:small intestine, large intestine:extracellular space (mouse) RGD PMID:26401072 RGD:11555935 NCBI chr12:15,394,487...15,414,609
Ensembl chr12:15,394,487...15,414,703 		JBrowse link
G ACE2 angiotensin converting enzyme 2 severity ISO Ace2 inhibitor
Ace2 knockout		 RGD PMID:19517214 PMID:22837003 RGD:40818307 RGD:40818410 NCBI chr  X:12,099,849...12,152,204
Ensembl chr  X:12,093,242...12,151,286 		JBrowse link
G CASP3 caspase 3 treatment ISO RGD PMID:28740344 RGD:13782278 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213 		JBrowse link
G CASP7 caspase 7 treatment ISO RGD PMID:28740344 RGD:13782278 NCBI chr14:124,017,776...124,050,369
Ensembl chr14:124,019,164...124,050,365 		JBrowse link
G SERPINA1 serpin family A member 1 treatment ISO RGD PMID:23835442 RGD:14695050 NCBI chr 7:115,604,282...115,616,915
Ensembl chr 7:115,583,043...115,614,645 		JBrowse link
Clostridium difficile colitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL23A interleukin 23 subunit alpha severity ISO RGD PMID:26455347 RGD:11097134 NCBI chr 5:21,732,416...21,733,981
Ensembl chr 5:21,732,165...21,734,267 		JBrowse link
G IL33 interleukin 33 severity
treatment		 ISO RGD PMID:32156806 RGD:40400894 NCBI chr 1:215,899,830...215,941,944
Ensembl chr 1:215,899,436...215,941,840 		JBrowse link
Experimental Colitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme treatment ISO RGD PMID:17342403 PMID:24239644 RGD:40400720 RGD:40400748 NCBI chr12:15,394,487...15,414,609
Ensembl chr12:15,394,487...15,414,703 		JBrowse link
G ACER3 alkaline ceramidase 3 severity ISO mRNA,protein:decreased expression, decreased activity:colon: RGD PMID:26938296 RGD:35673322 NCBI chr 9:10,985,078...11,167,386
Ensembl chr 9:10,967,857...11,162,502 		JBrowse link
G ADAM17 ADAM metallopeptidase domain 17 treatment ISO RGD PMID:11884025 RGD:632022 NCBI chr 3:126,795,513...126,853,995
Ensembl chr 3:126,795,426...126,853,995 		JBrowse link
G ADRB3 adrenoceptor beta 3 no_association ISO mRNA:unaltered expression:colon (rat) RGD PMID:11803250 RGD:5684894 NCBI chr15:48,468,803...48,478,370
Ensembl chr15:48,475,144...48,479,562 		JBrowse link
G AGER advanced glycosylation end-product specific receptor treatment ISO RGD PMID:29572553 RGD:152995414 NCBI chr 7:24,218,116...24,221,162
Ensembl chr 7:24,218,120...24,221,162 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 treatment ISO RGD PMID:29572553 RGD:152995414
G ATM ATM serine/threonine kinase exacerbates ISO RGD PMID:20179206 RGD:126781749 NCBI chr 9:36,620,656...36,759,555
Ensembl chr 9:36,620,657...36,759,552 		JBrowse link
G ATP5F1A ATP synthase F1 subunit alpha treatment ISO RGD PMID:25689466 RGD:13703055 NCBI chr 1:95,738,789...95,750,835
Ensembl chr 1:95,733,090...95,750,841 		JBrowse link
G BCL2 BCL2 apoptosis regulator treatment ISO RGD PMID:29572553 RGD:152995414 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879 		JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 exacerbates ISO RGD PMID:26037070 RGD:11537970 NCBI chr 9:33,003,570...33,020,252
Ensembl chr 9:33,002,734...33,020,242 		JBrowse link
G CD68 CD68 molecule treatment ISO RGD PMID:25004394 RGD:40925931 NCBI chr12:52,874,754...52,877,256
Ensembl chr12:52,874,785...52,877,695 		JBrowse link
G CHRNA7 cholinergic receptor nicotinic alpha 7 subunit treatment ISO RGD PMID:29572553 RGD:152995414 NCBI chr 1:142,803,697...142,937,124
Ensembl chr 1:142,803,701...142,937,123 		JBrowse link
G CSF1R colony stimulating factor 1 receptor ameliorates ISO RGD PMID:23451116 RGD:150524300 NCBI chr 2:151,102,138...151,130,311
Ensembl chr 2:151,102,147...151,147,633 		JBrowse link
G CSF3 colony stimulating factor 3 treatment ISO RGD PMID:16689657 RGD:11039462 NCBI chr12:22,333,445...22,335,949
Ensembl chr12:22,333,449...22,338,753 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 treatment ISO RGD PMID:29655167 RGD:39939058 NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861 		JBrowse link
G EREG epiregulin ISO protein:increased expression:colonic mucosa (mouse) RGD PMID:20498653 RGD:39457688 NCBI chr 8:70,351,316...70,372,530
Ensembl chr 8:70,351,311...70,372,569 		JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit treatment ISO RGD PMID:31160593 RGD:126779602 NCBI chr 9:109,384,976...109,450,943
Ensembl chr 9:109,385,015...109,450,941 		JBrowse link
G FAS Fas cell surface death receptor treatment ISO RGD PMID:22368862 RGD:10054108 NCBI chr14:100,927,305...100,954,781
Ensembl chr14:100,927,089...100,956,716 		JBrowse link
G FGF10 fibroblast growth factor 10 treatment ISO human protein in mouse model
human gene product in mouse model
human protein in mouse model with bacterial delivery system		 RGD PMID:10381813 PMID:11952999 PMID:19736360 PMID:23676805 RGD:126928132 RGD:126928133 RGD:127284855 RGD:127284874 NCBI chr16:28,695,465...28,779,953
Ensembl chr16:28,695,470...28,777,509 		JBrowse link
G FGF7 fibroblast growth factor 7 treatment ISO human protein in mouse model RGD PMID:10219846 RGD:126928136 NCBI chr 1:122,215,878...122,278,705
Ensembl chr 1:122,215,882...122,277,750 		JBrowse link
G FOXP3 forkhead box P3 treatment ISO mRNA:increased expression:mucosa:
protein:increased expression:colon:		 RGD PMID:17229795 PMID:26925602 PMID:27498708 PMID:28733028 RGD:14975101 RGD:38455994 RGD:38455995 RGD:38549362 NCBI chr  X:43,303,777...43,328,164
Ensembl chr  X:43,303,785...43,322,968 		JBrowse link
G HAMP hepcidin antimicrobial peptide ISO protein:increased expression:colon RGD PMID:24764672 RGD:11041628 NCBI chr 6:44,785,863...44,787,303
Ensembl chr 6:44,784,160...44,787,305 		JBrowse link
G HMGB1 high mobility group box 1 treatment ISO RGD PMID:29572553 RGD:152995414 NCBI chr11:7,195,556...7,321,071 JBrowse link
G HSF1 heat shock transcription factor 1 ISO protein:increased acetylation:colon (rat) RGD PMID:25608526 RGD:10402402 NCBI chr 4:463,531...486,483
Ensembl chr 4:463,393...486,473 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 treatment ISO RGD PMID:10092309 PMID:29572553 RGD:11522714 RGD:152995414 NCBI chr 2:69,097,136...69,107,722
Ensembl chr 2:69,097,122...69,108,205 		JBrowse link
G IFNG interferon gamma ISO protein:increased expression:plasma: RGD PMID:15030379 PMID:27498708 RGD:10755756 RGD:14975101 NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,906...32,482,670 		JBrowse link
G IFNGR1 interferon gamma receptor 1 ameliorates ISO RGD PMID:25918247 RGD:124715468 NCBI chr 1:27,037,151...27,061,095
Ensembl chr 1:27,037,165...27,061,093 		JBrowse link
G IL10 interleukin 10 treatment ISO associated with Helicobacter Infections RGD PMID:16982822 PMID:25727887 PMID:27815529 PMID:29572553 RGD:11049170 RGD:11049485 RGD:14975260 RGD:152995414 NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,728...67,405,378 		JBrowse link
G IL1RN interleukin 1 receptor antagonist treatment ISO human protein in a rat model RGD PMID:8978354 RGD:8551835
G IL2 interleukin 2 ISO RGD PMID:16630696 RGD:8662978 NCBI chr 8:101,640,938...101,645,683
Ensembl chr 8:101,640,944...101,645,609 		JBrowse link
G IL23A interleukin 23 subunit alpha severity ISO mRNA:increased expression:colon (mouse) RGD PMID:24028683 RGD:39458035 NCBI chr 5:21,732,416...21,733,981
Ensembl chr 5:21,732,165...21,734,267 		JBrowse link
G IL25 interleukin 25 treatment ISO RGD PMID:19118508 RGD:39456129 NCBI chr 7:75,710,453...75,717,688
Ensembl chr 7:75,709,995...75,714,355 		JBrowse link
G IL33 interleukin 33 severity
treatment		 ISO RGD PMID:25112700 PMID:28423665 RGD:39938951 RGD:39939041 NCBI chr 1:215,899,830...215,941,944
Ensembl chr 1:215,899,436...215,941,840 		JBrowse link
G IL6 interleukin 6 treatment ISO RGD PMID:16133010 PMID:16630696 PMID:27096537 RGD:11062139 RGD:11062146 RGD:8662978 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263 		JBrowse link
G IRF9 interferon regulatory factor 9 ameliorates ISO RGD PMID:25918247 RGD:124715468 NCBI chr 7:75,133,800...75,139,641
Ensembl chr 7:75,126,622...75,139,640 		JBrowse link
G ITGA2 integrin subunit alpha 2 treatment ISO RGD PMID:16534417 RGD:11530069 NCBI chr16:32,336,240...32,440,311
Ensembl chr16:32,336,292...32,437,103 		JBrowse link
G ITGA4 integrin subunit alpha 4 ISO protein:increased expression:colon (rat) RGD PMID:12183646 RGD:729408 NCBI chr15:86,942,054...87,028,428
Ensembl chr15:86,947,240...87,030,364 		JBrowse link
G JAK2 Janus kinase 2 treatment ISO RGD PMID:29572553 RGD:152995414 NCBI chr 1:216,849,744...217,002,310
Ensembl chr 1:216,848,689...217,002,148 		JBrowse link
G KCNMA1 potassium calcium-activated channel subfamily M alpha 1 ISO mRNA, protein:increased expression:colon RGD PMID:23986198 RGD:10412026 NCBI chr14:79,345,382...80,106,337
Ensembl chr14:79,352,005...80,106,295 		JBrowse link
G KDR kinase insert domain receptor ISO protein:increased expression:colon RGD PMID:19013462 RGD:5684406 NCBI chr 8:41,809,116...41,856,379
Ensembl chr 8:41,809,122...41,856,336 		JBrowse link
G KL klotho ISO mRNA:decreased expression:kidney: RGD PMID:20004202 RGD:10403055 NCBI chr11:9,427,236...9,479,251
Ensembl chr11:9,427,037...9,479,228 		JBrowse link
G LOC110258578 interleukin-1 beta-like treatment ISO RGD PMID:31175857 RGD:14975282
G MAPK1 mitogen-activated protein kinase 1 treatment ISO RGD PMID:27028006 RGD:13800882 NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,513 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 treatment ISO RGD PMID:29037916 RGD:13800567 NCBI chr 3:18,291,444...18,299,410
Ensembl chr 3:18,291,445...18,299,567 		JBrowse link
G MIF macrophage migration inhibitory factor severity ISO RGD PMID:15807847 RGD:36947390 NCBI chr14:49,840,303...49,841,063
Ensembl chr14:49,840,305...49,841,068 		JBrowse link
G MIR155 microRNA mir-155 treatment ISO associated with Helicobacter Infections RGD PMID:21880981 PMID:28246471 PMID:28461115 PMID:28752563 PMID:30253332 More... RGD:21079443 RGD:21079463 RGD:21079473 RGD:21081536 RGD:24922208 RGD:25314295 NCBI chr13:189,138,822...189,138,902
Ensembl chr13:189,138,822...189,138,902 		JBrowse link
G MIR21 microRNA mir-21 ameliorates ISO RGD PMID:23826144 RGD:41404691 NCBI chr12:36,065,267...36,065,358
Ensembl chr12:36,065,267...36,065,358 		JBrowse link
G MMP2 matrix metallopeptidase 2 treatment ISO RGD PMID:23323009 RGD:13207328 NCBI chr 6:30,059,247...30,087,031
Ensembl chr 6:30,058,595...30,086,982 		JBrowse link
G MMP9 matrix metallopeptidase 9 treatment ISO RGD PMID:23323009 RGD:13207328 NCBI chr17:48,179,690...48,186,782
Ensembl chr17:48,179,671...48,186,788 		JBrowse link
G MPO myeloperoxidase treatment ISO RGD PMID:29572553 RGD:152995414 NCBI chr12:34,557,031...34,570,091
Ensembl chr12:34,556,408...34,567,904 		JBrowse link
G MSC musculin exacerbates
no_association		 ISO RGD PMID:33448336 PMID:36848960 RGD:596936211 RGD:596936221 NCBI chr 4:63,709,800...63,712,651
Ensembl chr 4:63,709,795...63,713,140 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor exacerbates ISO RGD PMID:25362351 RGD:150521530 NCBI chr13:22,976,951...22,979,568
Ensembl chr13:22,966,137...22,983,109 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 treatment ISO RGD PMID:22350949 RGD:10412739 NCBI chr15:82,967,485...83,146,185
Ensembl chr15:82,973,656...83,146,183 		JBrowse link
G NFKBIA NFKB inhibitor alpha treatment ISO RGD PMID:21642017 RGD:10413866 NCBI chr 7:64,508,119...64,510,754
Ensembl chr 7:64,507,822...64,511,277 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 ISO protein:increased expression:colonic mucosa: RGD PMID:22997830 RGD:13204727 NCBI chr 6:34,132,127...34,167,446
Ensembl chr 6:34,130,938...34,177,534 		JBrowse link
G NPY neuropeptide Y treatment ISO RGD PMID:20533056 RGD:10448943 NCBI chr18:47,985,796...47,993,726
Ensembl chr18:47,985,725...47,992,667 		JBrowse link
G PDGFRA platelet derived growth factor receptor alpha treatment ISO RGD PMID:24115822 RGD:11080973 NCBI chr 8:40,966,568...41,021,440
Ensembl chr 8:40,967,493...41,021,441 		JBrowse link
G PDGFRB platelet derived growth factor receptor beta treatment ISO RGD PMID:24115822 RGD:11080973 NCBI chr 2:151,155,753...151,192,818
Ensembl chr 2:151,155,756...151,192,647 		JBrowse link
G PHEX phosphate regulating endopeptidase X-linked ISO mRNA:decreased expression:bone: RGD PMID:16890604 RGD:11556253 NCBI chr  X:18,199,396...18,420,985
Ensembl chr  X:18,203,174...18,418,004 		JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma susceptibility ISO RGD PMID:20347874 RGD:38599183 NCBI chr 9:106,698,200...106,748,217
Ensembl chr 9:106,698,207...106,745,099 		JBrowse link
G PTGER4 prostaglandin E receptor 4 treatment ISO RGD PMID:12100473 RGD:727388 NCBI chr16:25,670,832...25,686,556
Ensembl chr16:25,670,862...25,686,552 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit treatment ISO RGD PMID:29572553 RGD:152995414 NCBI chr 2:6,594,869...6,602,684
Ensembl chr 2:6,593,969...6,603,469 		JBrowse link
G RNASEL ribonuclease L severity ISO RGD PMID:23567782 RGD:40902808 NCBI chr 9:123,895,045...123,910,386
Ensembl chr 9:123,893,294...123,910,398 		JBrowse link
G SLC11A1 solute carrier family 11 member 1 ISO RGD PMID:19116231 RGD:5684934 NCBI chr15:120,434,100...120,446,396
Ensembl chr15:120,433,952...120,446,396 		JBrowse link
G SMAD3 SMAD family member 3 ISO protein:increased expression:colon RGD PMID:30064196 RGD:597830080 NCBI chr 1:164,998,457...165,124,455
Ensembl chr 1:164,998,103...165,124,449 		JBrowse link
G SMAD4 SMAD family member 4 susceptibility ISO RGD PMID:23090737 RGD:12880038 NCBI chr 1:100,521,843...100,633,501
Ensembl chr 1:100,589,850...100,628,029 		JBrowse link
G SOCS3 suppressor of cytokine signaling 3 treatment ISO RGD PMID:29572553 RGD:152995414 NCBI chr12:3,643,832...3,647,015
Ensembl chr12:3,643,929...3,647,009 		JBrowse link
G TNF tumor necrosis factor treatment ISO RGD PMID:21296062 PMID:29572553 RGD:152995414 RGD:8661763 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,415 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A treatment ISO RGD PMID:21296062 RGD:8661763 NCBI chr 5:64,319,349...64,331,876
Ensembl chr 5:64,319,051...64,331,909 		JBrowse link
G VEGFA vascular endothelial growth factor A ISO protein:increased expression:colon RGD PMID:19013462 RGD:5684406 NCBI chr 7:38,746,393...38,762,282
Ensembl chr 7:38,746,052...38,761,366 		JBrowse link
ischemic colitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SERPINE1 serpin family E member 1 susceptibility ISO DNA:polymorphism:promoter:rs1799768 (human) RGD PMID:25656775 RGD:13208543 NCBI chr 3:8,863,738...8,871,572
Ensembl chr 3:8,863,695...8,871,547 		JBrowse link
G VEGFA vascular endothelial growth factor A ISO RGD PMID:15770733 RGD:1580570 NCBI chr 7:38,746,393...38,762,282
Ensembl chr 7:38,746,052...38,761,366 		JBrowse link
Proctocolitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL1RN interleukin 1 receptor antagonist ISO protein:increased concentration:serum (human) RGD PMID:9802632 RGD:6909134
ulcerative colitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 susceptibility ISO RGD PMID:15505619 RGD:1598568 NCBI chr 9:93,049,955...93,146,469 JBrowse link
G ACSM3 acyl-CoA synthetase medium chain family member 3 ISO mRNA:decreased expression:colonic mucosa RGD PMID:21987487 RGD:7241281 NCBI chr 3:25,247,723...25,284,063
Ensembl chr 3:25,247,725...25,283,709 		JBrowse link
G ADCY7 adenylate cyclase 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28067910 NCBI chr 6:34,521,503...34,586,384
Ensembl chr 6:34,519,180...34,585,779 		JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing ISO protein:increased expression:serum RGD PMID:16432373 RGD:5686726 NCBI chr13:124,633,906...124,646,237
Ensembl chr13:124,633,685...124,646,646 		JBrowse link
G ADRB2 adrenoceptor beta 2 ISO protein:decreased expression:large intestine mucosa,spleen RGD PMID:22772914 RGD:7175063 NCBI chr 2:150,032,649...150,035,591
Ensembl chr 2:150,033,579...150,040,731 		JBrowse link
G ALB albumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:35999755 NCBI chr 8:69,643,427...69,663,152
Ensembl chr 8:69,531,487...69,721,696 		JBrowse link
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO protein:increased expression:large intestine epithelium RGD PMID:7679252 RGD:5509621 NCBI chr12:52,401,861...52,414,913
Ensembl chr12:52,401,810...52,414,903 		JBrowse link
G APLN apelin ISO protein:increased expression:intestine RGD PMID:17391779 RGD:1626177 NCBI chr  X:106,236,746...106,246,563
Ensembl chr  X:106,236,749...106,246,377 		JBrowse link
G APOA4 apolipoprotein A4 severity ISO DNA:missense mutation:cds:p.Q360H (human)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:17206692 PMID:35999755 RGD:5685660 NCBI chr 9:44,201,587...44,204,072
Ensembl chr 9:44,201,508...44,204,206 		JBrowse link
G AQP7 aquaporin 7 severity ISO mRNA, protein:decreased expression:colon RGD PMID:15338270 RGD:1626292 NCBI chr10:33,098,746...33,130,245 JBrowse link
G ARPC2 actin related protein 2/3 complex subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18836448 NCBI chr15:120,297,122...120,328,795
Ensembl chr15:120,297,025...120,328,542 		JBrowse link
G BCL6 BCL6 transcription repressor ISO CTD Direct Evidence: therapeutic CTD PMID:38164749 NCBI chr13:125,377,247...125,401,328
Ensembl chr13:125,377,250...125,393,330 		JBrowse link
G BRINP3 BMP/retinoic acid inducible neural specific 3 ISO mRNA,protein:decreased expression:intestine RGD PMID:25171508 RGD:14398484 NCBI chr10:2,963,237...3,367,629
Ensembl chr10:2,963,527...3,367,623 		JBrowse link
G BTNL2 butyrophilin like 2 susceptibility ISO DNA:SNPs: : rs2294881,rs9268480,rs2076523(human) RGD PMID:19659809 RGD:9685032 NCBI chr 7:24,789,988...24,809,920
Ensembl chr 7:24,789,888...24,810,132 		JBrowse link
G C3 complement C3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35999755 NCBI chr 2:72,431,470...72,471,622
Ensembl chr 2:72,431,212...72,472,228 		JBrowse link
G CARD9 caspase recruitment domain family member 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799
G CASP3 caspase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24055189 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213 		JBrowse link
G CCL20 C-C motif chemokine ligand 20 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:16306769 PMID:21887805 RGD:7488892 NCBI chr15:129,172,743...129,176,069 JBrowse link
G CCNY cyclin Y ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438405 NCBI chr10:57,929,484...58,057,964
Ensembl chr10:57,929,244...58,086,872 		JBrowse link
G CCR2 C-C motif chemokine receptor 2 ISO RGD PMID:21077277 RGD:6892920 NCBI chr13:29,251,950...29,286,470
Ensembl chr13:29,285,012...29,286,467 		JBrowse link
G CCR6 C-C motif chemokine receptor 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16306769 NCBI chr 1:2,016,600...2,034,172
Ensembl chr 1:2,018,608...2,019,821 		JBrowse link
G CD40 CD40 molecule ISO protein:increased expression:intestine, epithelial cell RGD PMID:20133813 RGD:5490590 NCBI chr17:48,286,116...48,298,188
Ensembl chr17:48,286,029...48,298,528 		JBrowse link
G CDH1 cadherin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19915572 NCBI chr 6:18,075,487...18,155,986
Ensembl chr 6:18,075,480...18,155,986 		JBrowse link
G CDH3 cadherin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19915572 NCBI chr 6:18,190,971...18,236,184
Ensembl chr 6:18,191,664...18,235,862 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A disease_progression ISO RGD PMID:15743319 RGD:8662406 NCBI chr 7:32,354,776...32,363,771
Ensembl chr 7:32,354,672...32,363,761 		JBrowse link
G CFB complement factor B ISO CTD Direct Evidence: marker/mechanism CTD PMID:35999755 NCBI chr 7:24,034,077...24,040,523
Ensembl chr 7:24,034,332...24,041,179 		JBrowse link
G CHRNA7 cholinergic receptor nicotinic alpha 7 subunit ISO mRNA:increased expression:intestine: RGD PMID:27051591 RGD:151667910 NCBI chr 1:142,803,697...142,937,124
Ensembl chr 1:142,803,701...142,937,123 		JBrowse link
G COL18A1 collagen type XVIII alpha 1 chain ISO Protein:increased expression:large intestine mucosa RGD PMID:17011522 RGD:1600887 NCBI chr13:207,907,835...207,984,082
Ensembl chr13:207,940,948...207,982,938 		JBrowse link
G COL1A1 collagen type I alpha 1 chain ISO RGD PMID:17939044 RGD:5688304 NCBI chr12:26,379,087...26,397,180
Ensembl chr12:26,379,090...26,397,004 		JBrowse link
G COL6A3 collagen type VI alpha 3 chain ISO protein:increased expression:serum (human) RGD PMID:32245981 RGD:401900121 NCBI chr15:137,011,549...137,103,687
Ensembl chr15:137,011,433...137,103,709 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12133438 PMID:15955209 NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861 		JBrowse link
G CXCR2 C-X-C motif chemokine receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr15:120,219,657...120,230,203 JBrowse link
G CXCR3 C-X-C motif chemokine receptor 3 ISO mRNA:increased expression:peripheral blood immature plasma cells RGD PMID:21087446 RGD:6480657 NCBI chr  X:57,592,032...57,595,706
Ensembl chr  X:57,592,038...57,595,692 		JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 ISO mRNA:increased expression:peripheral blood immature plasma cells RGD PMID:21087446 RGD:6480657 NCBI chr15:15,663,652...15,666,706
Ensembl chr15:15,663,494...15,667,232 		JBrowse link
G CYP24A1 cytochrome P450 family 24 subfamily A member 1 susceptibility ISO DNA:SNPs:multiple (human) RGD PMID:28811712 RGD:151665177 NCBI chr17:55,110,546...55,130,328
Ensembl chr17:55,110,590...55,130,363 		JBrowse link
G DAP death associated protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr16:250,212...322,075
Ensembl chr16:250,217...321,929 		JBrowse link
G DPEP1 dipeptidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35999755 NCBI chr 6:361,187...385,757
Ensembl chr 6:361,197...376,616 		JBrowse link
G DUOX2 dual oxidase 2 ISO mRNA:increased expression:colon (human) RGD PMID:19759286 RGD:40924645 NCBI chr 1:126,620,468...126,641,406
Ensembl chr 1:126,620,510...126,641,406 		JBrowse link
G ECM1 extracellular matrix protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438406 NCBI chr 4:98,615,776...98,633,081
Ensembl chr 4:98,615,778...98,621,836 		JBrowse link
G EPHB2 EPH receptor B2 ameliorates ISO RGD PMID:33722292 RGD:127285641 NCBI chr 6:80,649,098...80,849,979
Ensembl chr 6:80,650,740...80,843,567 		JBrowse link
G ESR2 estrogen receptor 2 ISO mRNA:decreased expression:colon RGD PMID:21252046 RGD:5508810 NCBI chr 1:193,823,666...193,907,330
Ensembl chr 1:193,829,560...193,906,565 		JBrowse link
G F2 coagulation factor II, thrombin ISO RGD PMID:21593018 RGD:5147754 NCBI chr 2:15,793,257...15,819,151
Ensembl chr 2:15,791,455...15,819,137 		JBrowse link
G FAS Fas cell surface death receptor treatment ISO RGD PMID:30122878 RGD:13792562 NCBI chr14:100,927,305...100,954,781
Ensembl chr14:100,927,089...100,956,716 		JBrowse link
G FASLG Fas ligand treatment ISO RGD PMID:30122878 RGD:13792562 NCBI chr 9:115,068,314...115,075,147
Ensembl chr 9:115,068,090...115,076,464 		JBrowse link
G FGF7 fibroblast growth factor 7 ISO mRNA:increased expression:colon, lamina propria, myofibroblasts (human) RGD PMID:9358773 RGD:126928145 NCBI chr 1:122,215,878...122,278,705
Ensembl chr 1:122,215,882...122,277,750 		JBrowse link
G GC GC vitamin D binding protein susceptibility ISO DNA:polymorphism:cds:p.T420K(human) RGD PMID:21832969 RGD:5509866 NCBI chr 8:68,326,293...68,360,262
Ensembl chr 8:68,326,299...68,360,262 		JBrowse link
G GHRL ghrelin and obestatin prepropeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:19617644 NCBI chr13:66,442,106...66,453,576
Ensembl chr13:66,445,992...66,452,917 		JBrowse link
G GNA12 G protein subunit alpha 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr 3:2,002,494...2,105,937
Ensembl chr 3:2,004,471...2,105,952 		JBrowse link
G GPR65 G protein-coupled receptor 65 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30616622 NCBI chr 7:109,978,913...109,997,688
Ensembl chr 7:109,985,307...109,989,280 		JBrowse link
G GPX1 glutathione peroxidase 1 ISO protein:decreased expression:erythrocyte RGD PMID:20186929 RGD:11352754 NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,916,246...31,917,433 		JBrowse link
G GPX2 glutathione peroxidase 2 disease_progression ISO protein:increased expression:large intestine (human) RGD PMID:18479189 RGD:152998902 NCBI chr 7:89,007,636...89,011,620
Ensembl chr 7:89,007,375...89,011,620 		JBrowse link
G HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438405 NCBI chr15:56,438,117...56,649,805
Ensembl chr15:56,438,148...56,649,792 		JBrowse link
G HNF4A hepatocyte nuclear factor 4 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:19915572 NCBI chr17:46,783,772...46,847,505
Ensembl chr17:46,783,777...46,847,500 		JBrowse link
G HNMT histamine N-methyltransferase ISO RGD PMID:18340362 RGD:5509777 NCBI chr15:13,733,412...13,768,106
Ensembl chr15:13,732,680...13,768,199 		JBrowse link
G HP haptoglobin ISO CTD Direct Evidence: marker/mechanism CTD PMID:35999755 NCBI chr 6:14,980,382...14,985,245 JBrowse link
G HSPA4 heat shock protein family A (Hsp70) member 4 ISO protein:increased expression:colon mucosa, epithelium (human) RGD PMID:22297444 RGD:5688753 NCBI chr 2:135,345,724...135,391,112
Ensembl chr 2:135,345,867...135,391,108 		JBrowse link
G HTRA1 HtrA serine peptidase 1 ISO protein:decreased expression:colonic epithelium,colonic mucosa (human) RGD PMID:28586045 RGD:152985530 NCBI chr14:132,043,044...132,103,590
Ensembl chr14:132,041,934...132,103,595 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO mRNA:increased expression:substantia nigra (rat)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:15553846 PMID:20584104 RGD:4145388 NCBI chr 2:69,097,136...69,107,722
Ensembl chr 2:69,097,122...69,108,205 		JBrowse link
G ICOSLG inducible T cell costimulator ligand ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chr13:207,106,202...207,115,886 JBrowse link
G IGF1R insulin like growth factor 1 receptor ISO protein:altered expression:colon RGD PMID:18938767 RGD:5686432 NCBI chr 1:137,383,623...137,691,038
Ensembl chr 1:137,387,825...137,691,058 		JBrowse link
G IGF2 insulin like growth factor 2 disease_progression ISO RGD PMID:16088202 RGD:5509966 NCBI chr 2:1,469,183...1,496,417 JBrowse link
G IKZF1 IKAROS family zinc finger 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chr 9:136,372,202...136,464,942
Ensembl chr 9:136,372,725...136,464,940 		JBrowse link
G IL10 interleukin 10 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:18836448 PMID:20228799 PMID:26660358 PMID:28120341 RGD:14975153 RGD:14975255 NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,728...67,405,378 		JBrowse link
G IL12B interleukin 12B ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438406 PMID:20228799 PMID:21297633 NCBI chr16:64,143,268...64,158,929
Ensembl chr16:64,143,268...64,158,929 		JBrowse link
G IL17REL interleukin 17 receptor E like ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228798 NCBI chr 5:645,882...662,552
Ensembl chr 5:646,879...664,018 		JBrowse link
G IL18RAP interleukin 18 receptor accessory protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chr 3:51,762,111...51,794,552
Ensembl chr 3:51,762,486...51,794,471 		JBrowse link
G IL1R2 interleukin 1 receptor type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr 3:52,367,434...52,406,393
Ensembl chr 3:52,367,437...52,406,334 		JBrowse link
G IL1RN interleukin 1 receptor antagonist ISO DNA:repeats:intron:IVS2+914_1000dup IL1RN*2 (human) RGD PMID:8119534 RGD:6909136
G IL23R interleukin 23 receptor ISO CTD Direct Evidence: marker/mechanism
DNA:SNP,Haplotype: :rs1884444(human)		 CTD
RGD		 PMID:18438406 PMID:19122664 PMID:20228799 PMID:23093364 RGD:8549574 NCBI chr 6:145,337,765...145,401,909
Ensembl chr 6:145,335,741...145,401,510 		JBrowse link
G IL33 interleukin 33 severity
treatment		 ISO mRNA:increased expression:sigmoid colon RGD PMID:21037074 PMID:25112700 PMID:28802904 RGD:39938951 RGD:39938966 RGD:40813742 NCBI chr 1:215,899,830...215,941,944
Ensembl chr 1:215,899,436...215,941,840 		JBrowse link
G IL7R interleukin 7 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr16:21,300,141...21,330,156
Ensembl chr16:21,300,111...21,329,585 		JBrowse link
G IRF4 interferon regulatory factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:38164749 NCBI chr 7:133,358...149,609
Ensembl chr 7:133,371...149,609 		JBrowse link
G IRF5 interferon regulatory factor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr18:19,678,377...19,691,154
Ensembl chr18:19,678,687...19,691,243 		JBrowse link
G JAK2 Janus kinase 2 ISO DNA:SNP: :rs10758669 (human)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:20228799 PMID:21297633 PMID:22269120 RGD:6483020 NCBI chr 1:216,849,744...217,002,310
Ensembl chr 1:216,848,689...217,002,148 		JBrowse link
G KDR kinase insert domain receptor ISO protein:increased expression:colon RGD PMID:19013462 RGD:5684406 NCBI chr 8:41,809,116...41,856,379
Ensembl chr 8:41,809,122...41,856,336 		JBrowse link
G KIF21B kinesin family member 21B ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chr10:23,444,997...23,491,081
Ensembl chr10:23,445,000...23,491,181 		JBrowse link
G LAMB1 laminin subunit beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19915572 NCBI chr 9:107,670,120...107,747,242
Ensembl chr 9:107,671,152...107,772,269 		JBrowse link
G LOC110258578 interleukin-1 beta-like ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:lung		 CTD
RGD		 PMID:12133438 PMID:15955209 PMID:20452301 PMID:22119283 PMID:24812904 RGD:10450593
G LSP1 lymphocyte specific protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr 2:1,261,957...1,295,891
Ensembl chr 2:1,262,079...1,295,887 		JBrowse link
G LTF lactotransferrin ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:16640825 PMID:35999755 NCBI chr13:29,413,886...29,445,751
Ensembl chr13:29,413,886...29,445,739 		JBrowse link
G MASP2 MBL associated serine protease 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12904520 NCBI chr 6:71,224,637...71,243,041
Ensembl chr 6:71,224,637...71,243,874 		JBrowse link
G MIR155 microRNA mir-155 ISO miRNA:increased expression:colon
miRNA:decreased expression:feces		 RGD PMID:29325325 PMID:29438285 PMID:29668922 PMID:30927737 RGD:21079443 RGD:21403682 RGD:24922207 RGD:24922213 NCBI chr13:189,138,822...189,138,902
Ensembl chr13:189,138,822...189,138,902 		JBrowse link
G MIR31 microRNA mir-31 ISO miRNA:increased expression:colon RGD PMID:29438285 RGD:21403682 NCBI chr 1:201,198,732...201,198,809
Ensembl chr 1:201,198,732...201,198,809 		JBrowse link
G MMP1 matrix metallopeptidase 1 ISO RGD PMID:18837084 RGD:7207395 NCBI chr 9:33,411,738...33,420,205
Ensembl chr 9:33,411,065...33,420,076 		JBrowse link
G MMP9 matrix metallopeptidase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22119283 NCBI chr17:48,179,690...48,186,782
Ensembl chr17:48,179,671...48,186,788 		JBrowse link
G MPO myeloperoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20380826 PMID:22119283 PMID:24055189 NCBI chr12:34,557,031...34,570,091
Ensembl chr12:34,556,408...34,567,904 		JBrowse link
G MST1 macrophage stimulating 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438406 PMID:20228799 NCBI chr13:32,214,934...32,220,045
Ensembl chr13:32,214,937...32,219,902 		JBrowse link
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase susceptibility ISO DNA:polymorphism: :66A>G (human) RGD PMID:21947961 RGD:5508217 NCBI chr16:74,245,214...74,270,828
Ensembl chr16:74,245,228...74,270,783 		JBrowse link
G MUC2 mucin 2, oligomeric mucus/gel-forming ISO mRNA:altered expression: : RGD PMID:12870797 RGD:2324685 NCBI chr 2:689,363...719,542
Ensembl chr 2:689,364...710,330 		JBrowse link
G NKX2-3 NK2 homeobox 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438405 PMID:18438406 PMID:20228799 NCBI chr14:110,720,384...110,724,002
Ensembl chr14:110,720,394...110,723,995 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20452301 NCBI chr 6:34,132,127...34,167,446
Ensembl chr 6:34,130,938...34,177,534 		JBrowse link
G ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chr12:22,411,130...22,417,744
Ensembl chr12:22,411,587...22,417,736 		JBrowse link
G PON1 paraoxonase 1 ISO mRNA:decreased expression:colon RGD PMID:17664137 RGD:5509924 NCBI chr 9:74,943,646...74,974,720
Ensembl chr 9:74,926,048...74,974,723 		JBrowse link
G PON3 paraoxonase 3 ISO mRNA:decreased expression:colon RGD PMID:17664137 RGD:5509924 NCBI chr 9:74,983,040...75,017,947
Ensembl chr 9:74,991,277...75,017,942 		JBrowse link
G PRDM1 PR/SET domain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr 1:72,309,096...72,335,474
Ensembl chr 1:72,311,880...72,335,466 		JBrowse link
G PSMG1 proteasome assembly chaperone 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chr13:202,762,509...202,775,601
Ensembl chr13:202,762,512...202,775,642 		JBrowse link
G PTGER4 prostaglandin E receptor 4 ISO RGD PMID:21818367 RGD:6483532 NCBI chr16:25,670,832...25,686,556
Ensembl chr16:25,670,862...25,686,552 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO RGD PMID:17429720 RGD:2300267 NCBI chr 1:262,456,106...262,482,159
Ensembl chr 1:262,456,155...262,483,035 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:17429720 RGD:2300267 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884 		JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438405 NCBI chr 6:96,769,862...96,847,136
Ensembl chr 6:96,770,253...96,847,125 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:15955209 NCBI chr 2:6,594,869...6,602,684
Ensembl chr 2:6,593,969...6,603,469 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20452301 NCBI chr 4:47,026,558...47,075,133
Ensembl chr 4:47,027,098...47,074,704 		JBrowse link
G SELL selectin L ISO DNA:polymorphism: :p.F206L (human) RGD PMID:19212205 RGD:13464267 NCBI chr 4:81,306,363...81,325,296
Ensembl chr 4:81,306,353...81,326,444 		JBrowse link
G SELP selectin P ISO protein:increased expression:serum RGD PMID:21526498 RGD:6218993 NCBI chr 4:81,376,804...81,401,240
Ensembl chr 4:81,365,740...81,399,955 		JBrowse link
G SLC11A1 solute carrier family 11 member 1 ISO CTD Direct Evidence: marker/mechanism
DNA:polymorphism:promoter (human)
DNA:transition, repeat:promoter:-237C>T (human)		 CTD
RGD		 PMID:11929588 PMID:16059695 PMID:18340647 RGD:5684939 RGD:5684968 NCBI chr15:120,434,100...120,446,396
Ensembl chr15:120,433,952...120,446,396 		JBrowse link
G SLC26A3 solute carrier family 26 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19915573 NCBI chr 9:107,480,629...107,518,771
Ensembl chr 9:107,480,641...107,518,728 		JBrowse link
G SPHK1 sphingosine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24055189 NCBI chr12:5,114,946...5,122,580
Ensembl chr12:5,114,947...5,120,083 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO DNA:SNP: :rs744166 (human)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:18438405 PMID:20228799 PMID:22269120 RGD:6483020 NCBI chr12:20,407,316...20,471,091
Ensembl chr12:20,407,233...20,472,992 		JBrowse link
G THBD thrombomodulin ISO protein:decreased expression:colon, blood vessel RGD PMID:17557119 RGD:5685011 NCBI chr17:30,219,870...30,223,499
Ensembl chr17:30,217,303...30,224,099 		JBrowse link
G TNF tumor necrosis factor treatment ISO protein:increased expression:lung
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:19617644 PMID:20452301 PMID:22119283 PMID:24812904 PMID:25204186 More... RGD:10450577 RGD:10450593 RGD:14975153 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,415 		JBrowse link
G TNFAIP3 TNF alpha induced protein 3 severity ISO mRNA,protein:increased expression, decreased expression:colonic mucosa (human) RGD PMID:28842689 RGD:151347619 NCBI chr 1:26,474,158...26,489,771
Ensembl chr 1:26,473,938...26,489,822 		JBrowse link
G TNFSF15 TNF superfamily member 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chr 1:255,328,731...255,349,508
Ensembl chr 1:255,328,719...255,349,539 		JBrowse link
G VCAM1 vascular cell adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15553846 NCBI chr 4:117,496,914...117,511,211
Ensembl chr 4:117,496,920...117,511,222 		JBrowse link
G VEGFA vascular endothelial growth factor A ISO protein:increased expression:colon, plasma RGD PMID:19013462 RGD:5684406 NCBI chr 7:38,746,393...38,762,282
Ensembl chr 7:38,746,052...38,761,366 		JBrowse link
G VIP vasoactive intestinal peptide severity ISO mRNA:decreased expression:colon RGD PMID:22143367 RGD:5685619 NCBI chr 1:13,611,786...13,620,250
Ensembl chr 1:13,611,311...13,620,269 		JBrowse link
G VIPR1 vasoactive intestinal peptide receptor 1 ISO RGD PMID:17611633 RGD:5685618 NCBI chr13:26,036,610...26,073,168
Ensembl chr13:26,036,629...26,075,691 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15436
    disease of anatomical entity 15105
      gastrointestinal system disease 6572
        intestinal disease 2943
          inflammatory bowel disease 438
            colitis 245
              Clostridium difficile colitis 2
              Cutaneous Photosensitivity and Colitis, Lethal 0
              Experimental Colitis 70
              Leukoencephalopathy, Arthritis, Colitis, and Hypogammaglobulinemia 0
              Proctocolitis 1
              chemical colitis 5
              diversion colitis 0
              indeterminate colitis 0
              infectious colitis 0
              ischemic colitis 2
              microscopic colitis + 0
              pancolitis 0
              ulcerative colitis + 116
Path 2
Term Annotations click to browse term
  disease 15436
    Pathological Conditions, Signs and Symptoms 12097
      Pathologic Processes 7682
        Inflammation 2476
          gastroenteritis 520
            inflammatory bowel disease 438
              colitis 245
                Clostridium difficile colitis 2
                Cutaneous Photosensitivity and Colitis, Lethal 0
                Experimental Colitis 70
                Leukoencephalopathy, Arthritis, Colitis, and Hypogammaglobulinemia 0
                Proctocolitis 1
                chemical colitis 5
                diversion colitis 0
                indeterminate colitis 0
                infectious colitis 0
                ischemic colitis 2
                microscopic colitis + 0
                pancolitis 0
                ulcerative colitis + 116
paths to the root