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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:autoimmune disease of skin and connective tissue
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Accession:DOID:0060039 term browser browse the term
Definition:An autoimmune disease that is the abnormal functioning of the immune system that causes your immune system to produce antibodies or T cells against cells and/or tissues in the skin and connective tissue. (DO)
For additional species annotation, visit the Alliance of Genome Resources.

show annotations for term's descendants           Sort by:
 
alopecia areata term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 susceptibility ISO DNA:SNP:3'UTR:rs3087243(human)
CTD Direct Evidence: marker/mechanism		 CTD PMID:20596022, PMID:23567921 RGD:7411701 NCBI chr 9:67,699,397...67,706,068
Ensembl chr 9:67,699,379...67,706,065 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22358057 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930 		JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22358057 NCBI chr14:17,228,832...17,233,743
Ensembl chr14:17,228,856...17,234,712 		JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22358057 NCBI chr  X:71,614,346...71,616,997
Ensembl chr  X:71,614,346...71,616,997 		JBrowse link
G Dnmt1 DNA methyltransferase 1 ISO mRNA:increased expression:mononuclear cell: RGD PMID:21936853 RGD:9587460 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495 		JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 ISO mRNA:increased expression:mononuclear cell: RGD PMID:21936853 RGD:9587460 NCBI chr20:4,576,033...4,592,980
Ensembl chr20:4,576,057...4,592,980 		JBrowse link
G Hdac1 histone deacetylase 1 ISO mRNA:increased expression:mononuclear cell: RGD PMID:21936853 RGD:9587460 NCBI chr 5:147,716,664...147,743,723
Ensembl chr 5:147,716,664...147,743,723 		JBrowse link
G Hdac2 histone deacetylase 2 ISO mRNA:decreased expression:mononuclear cell: RGD PMID:21936853 RGD:9587460 NCBI chr20:43,084,870...43,108,198
Ensembl chr20:43,084,870...43,108,198 		JBrowse link
G Hdac7 histone deacetylase 7 ISO mRNA:decreased expression:mononuclear cell: RGD PMID:21936853 RGD:9587460 NCBI chr 7:139,280,396...139,319,108
Ensembl chr 7:139,281,187...139,318,455 		JBrowse link
G Ikzf4 IKAROS family zinc finger 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20596022 NCBI chr 7:3,061,422...3,098,142
Ensembl chr 7:3,061,469...3,074,359 		JBrowse link
G Il18 interleukin 18 susceptibility ISO DNA:SNPs:promoter, exon:-137G>C (rs187238), rs549908 (human) RGD PMID:24446726 RGD:8655875 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299 		JBrowse link
G Il1rn interleukin 1 receptor antagonist severity ISO DNA:repeats:intron:IVS2+914_1000dup IL1RN*2 (human) RGD PMID:8077705 RGD:6909137 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614 		JBrowse link
G Il2 interleukin 2 ISO RGD PMID:3261574, PMID:16297194 RGD:8663449, RGD:8663450 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854 		JBrowse link
G Il2ra interleukin 2 receptor subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:20596022 NCBI chr17:70,500,672...70,547,929
Ensembl chr17:70,499,083...70,548,071 		JBrowse link
G Kdm1a lysine demethylase 1A ISO mRNA:decreased expression:peripheral blood mononuclear cell (human) RGD PMID:21936853 RGD:9587460 NCBI chr 5:154,909,003...154,965,171
Ensembl chr 5:154,909,003...154,965,171 		JBrowse link
G Kdm4a lysine demethylase 4A ISO mRNA:decreased expression:peripheral blood mononuclear cell (human) RGD PMID:21936853 RGD:9587460 NCBI chr 5:136,967,650...137,014,402
Ensembl chr 5:136,967,650...137,014,430 		JBrowse link
G Kdm4b lysine demethylase 4B ISO mRNA:decreased expression:peripheral blood mononuclear cell (human) RGD PMID:21936853 RGD:9587460 NCBI chr 9:10,656,035...10,734,127
Ensembl chr 9:10,653,216...10,734,073 		JBrowse link
G Kdm4c lysine demethylase 4C ISO mRNA:increased expression:peripheral blood mononuclear cell (human) RGD PMID:21936853 RGD:9587460 NCBI chr 5:90,800,139...91,012,662
Ensembl chr 5:90,800,082...91,012,659 		JBrowse link
G Kdm5a lysine demethylase 5A ISO mRNA:increased expression:peripheral blood mononuclear cell (human) RGD PMID:21936853 RGD:9587460 NCBI chr 4:152,892,388...152,972,196
Ensembl chr 4:152,892,388...152,972,201 		JBrowse link
G Notch4 notch receptor 4 ISO RGD PMID:12589427 RGD:6480681 NCBI chr20:4,329,794...4,353,868
Ensembl chr20:4,329,811...4,353,785 		JBrowse link
G Prdx5 peroxiredoxin 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20596022 NCBI chr 1:222,164,462...222,167,447
Ensembl chr 1:222,164,462...222,167,447 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 severity ISO DNA:snp:cds:c.1858C>T (human) RGD PMID:16829308 RGD:6484734 NCBI chr 2:206,342,066...206,390,348
Ensembl chr 2:206,342,066...206,390,348 		JBrowse link
G RT1-Ba RT1 class II, locus Ba susceptibility ISO DNA:polymorphism: : HLA-DQA1*0104, HLA-DQA1*0606; RGD PMID:16231148 RGD:8547568 NCBI chr20:4,066,133...4,070,726
Ensembl chr20:4,066,132...4,070,721 		JBrowse link
G RT1-Bb RT1 class II, locus Bb susceptibility ISO DNA:polymorphism: : HLA-DQB1*0604; RGD PMID:16231148 RGD:8547568 NCBI chr20:4,043,726...4,049,367
Ensembl chr20:4,039,413...4,049,711 		JBrowse link
G Stx17 syntaxin 17 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20596022 NCBI chr 5:63,866,346...63,926,276
Ensembl chr 5:63,870,432...63,922,730 		JBrowse link
bullous pemphigoid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl26 C-C motif chemokine ligand 26 ISO protein:increased expression:blister, serum (human) RGD PMID:21881593 RGD:11087555 NCBI chr12:24,157,182...24,161,870
Ensembl chr12:24,158,766...24,161,869 		JBrowse link
G Cfb complement factor B ISO RGD PMID:17024247 RGD:7421522 NCBI chr20:4,536,206...4,542,073
Ensembl chr20:4,536,203...4,561,066
Ensembl chr20:4,536,203...4,561,066 		JBrowse link
G Col17a1 collagen type XVII alpha 1 chain ISS MouseDO NCBI chr 1:267,416,681...267,465,049
Ensembl chr 1:267,417,459...267,463,705 		JBrowse link
G F2 coagulation factor II ISO protein:increased expression:plasma RGD PMID:21488867 RGD:5147756 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031 		JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO RGD PMID:1377725 RGD:8547591 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059 		JBrowse link
G Il2 interleukin 2 ISO RGD PMID:1973607 RGD:8663461 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854 		JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO RGD PMID:9687525 RGD:8547843 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520 		JBrowse link
G Vegfa vascular endothelial growth factor A ISO mRNA:increased expression: : RGD PMID:7738351 RGD:7421578 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681 		JBrowse link
dermatitis herpetiformis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eln elastin ISO RGD PMID:8256113 RGD:9585750 NCBI chr12:24,978,478...25,021,864
Ensembl chr12:24,978,483...25,021,863 		JBrowse link
G Lta lymphotoxin alpha ISO DNA:polymorphism RGD PMID:7914110 RGD:8548777 NCBI chr20:4,851,889...4,854,677
Ensembl chr20:4,852,496...4,854,677 		JBrowse link
G Tnf tumor necrosis factor ISO DNA:polymorphism:promoter RGD PMID:7914110 RGD:8548777 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Vegfa vascular endothelial growth factor A ISO mRNA:increased expression: : RGD PMID:7738351 RGD:7421578 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681 		JBrowse link
hereditary spastic paraplegia 23 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dstyk dual serine/threonine and tyrosine protein kinase ISO OMIM NCBI chr13:49,195,325...49,243,327
Ensembl chr13:49,195,325...49,243,316 		JBrowse link
parapsoriasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100364500 RT1 class I, locus CE11-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:16538176 NCBI chr20:2,704,153...2,707,111
Ensembl chr20:2,704,148...2,707,120 		JBrowse link
G RT1-S3 RT1 class Ib, locus S3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16538176 NCBI chr20:3,176,124...3,180,825
Ensembl chr20:3,176,107...3,179,818 		JBrowse link
psoriasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb2 adrenoceptor beta 2 susceptibility ISO mRNA:decreased expression:epidermis:
DNA:polymorphism:cds:p.R16G(human)		 RGD PMID:8763426, PMID:15265530 RGD:8548488, RGD:8548492 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834 		JBrowse link
G Ager advanced glycosylation end product-specific receptor no_association ISO DNA:SNP: :2184A>G (human)
DNA:polymorphisms: :p.G82S, 1704G>T, 2245A>G (human)		 RGD PMID:12029499, PMID:12029499 RGD:8695975, RGD:8695975 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079 		JBrowse link
G Alb albumin ISO RGD PMID:22607558 RGD:6483512 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863 		JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type ISO protein:increased expression:keratinocyte RGD PMID:8304420 RGD:5509788 NCBI chr10:56,851,734...56,864,049
Ensembl chr10:56,851,734...56,864,005 		JBrowse link
G Anxa1 annexin A1 ISO RGD PMID:8919037 RGD:7421562 NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012 		JBrowse link
G Ap1s3 adaptor related protein complex 1 subunit sigma 3 ISO CTD Direct Evidence: marker/mechanism CTD NCBI chr 9:85,386,752...85,445,977
Ensembl chr 9:85,387,065...85,445,939 		JBrowse link
G Apoe apolipoprotein E susceptibility ISO DNA:SNP: :3937C>T(human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:exon:		 CTD PMID:16433808, PMID:16433808, PMID:19499236 RGD:7495788, RGD:7771595 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057 		JBrowse link
G Areg amphiregulin ISO RGD PMID:15955087 RGD:1578719 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179 		JBrowse link
G Arpc4 actin related protein 2/3 complex, subunit 4 ISS OMIM:177900 | OMIM:601454 | OMIM:603935 | OMIM:604316 | OMIM:605364 | OMIM:605606 | OMIM:607857 | OMIM:610707 | OMIM:612410 | OMIM:612599 | OMIM:612950 | OMIM:614070 | OMIM:616106 MouseDO NCBI chr 4:145,330,457...145,340,985
Ensembl chr 4:145,330,457...145,340,984 		JBrowse link
G Bank1 B-cell scaffold protein with ankyrin repeats 1 susceptibility ISO DNA:haplotype: : rs10516487, rs3733197, rs17266594(human) RGD PMID:21989138 RGD:9684977 NCBI chr 2:241,273,763...241,545,527
Ensembl chr 2:241,273,763...241,545,250 		JBrowse link
G C2 complement C2 ISO DNA:polymorphism: :C2*2 (human) RGD PMID:6559061 RGD:7411727 NCBI chr20:4,542,340...4,561,152
Ensembl chr20:4,542,340...4,561,152 		JBrowse link
G Cadm2 cell adhesion molecule 2 ISO RGD PMID:21864505 RGD:15092073 NCBI chr11:4,175,078...4,397,335
Ensembl chr11:4,174,881...4,397,361 		JBrowse link
G Card14 caspase recruitment domain family, member 14 ISO ClinVar Annotator: match by term: Psoriasis susceptibility 2
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD		 PMID:22521418, PMID:22521419, PMID:23143594, PMID:24212883 NCBI chr10:108,440,480...108,469,012
Ensembl chr10:108,440,950...108,468,310 		JBrowse link
G Carm1 coactivator-associated arginine methyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143594 NCBI chr 8:22,577,723...22,622,555
Ensembl chr 8:22,577,715...22,622,560 		JBrowse link
G Cast calpastatin ISO RGD PMID:15654835 RGD:5509819 NCBI chr 2:1,452,111...1,561,669
Ensembl chr 2:1,452,116...1,561,464 		JBrowse link
G Cat catalase treatment ISO protein:increased activity:serum:
CTD Direct Evidence: marker/mechanism
protein:decreased activity:liver:
protein:decreased activity:skin:		 CTD PMID:12559600, PMID:12602965, PMID:24018880, PMID:12165738 RGD:9479159, RGD:9479744, RGD:9479170 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058 		JBrowse link
G Cav1 caveolin 1 ISO protein:decreased expression:skin RGD PMID:12366416 RGD:8661784 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 treatment ISO mRNA:increased expression:skin RGD PMID:10843722, PMID:16081850, PMID:22895364 RGD:7483581, RGD:7483625, RGD:7483594 NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 ISO protein:increased expression:skin,monocyte: RGD PMID:15370700 RGD:8661734
G Ccr5 C-C motif chemokine receptor 5 ISO protein:decreased expression:T cell RGD PMID:23954573 RGD:8551838 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614 		JBrowse link
G Ccr6 C-C motif chemokine receptor 6 ISO mRNA:increased expression:skin RGD PMID:10843722, PMID:19662682 RGD:7483581, RGD:7483598 NCBI chr 1:53,063,380...53,087,519
Ensembl chr 1:53,065,025...53,087,474 		JBrowse link
G Cd40 CD40 molecule susceptibility ISO DNA:SNP:intron: (rs4810485) (human) RGD PMID:21645569 RGD:5490300 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A ISO mRNA,protein:increased expression:skin: RGD PMID:7636313 RGD:8662825 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864 		JBrowse link
G Cfb complement factor B no_association ISO DNA:polymorphisms RGD PMID:6559061, PMID:2609873 RGD:7411727, RGD:7421520 NCBI chr20:4,536,206...4,542,073
Ensembl chr20:4,536,203...4,561,066
Ensembl chr20:4,536,203...4,561,066 		JBrowse link
G Cfh complement factor H severity ISO protein:increased expression:plasma RGD PMID:2973157 RGD:8662318 NCBI chr13:56,979,155...57,080,540
Ensembl chr13:56,978,607...57,080,622 		JBrowse link
G Cfi complement factor I severity ISO protein:increased expression:plasma RGD PMID:2973157 RGD:8662318 NCBI chr 2:235,264,149...235,305,779
Ensembl chr 2:235,264,219...235,305,781 		JBrowse link
G Clu clusterin ISO protein:decreased expression:plasma RGD PMID:23522962 RGD:9068388 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857 		JBrowse link
G Comt catechol-O-methyltransferase ISO RGD PMID:24001377 RGD:8662328 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622 		JBrowse link
G Cp ceruloplasmin ISO CTD Direct Evidence: marker/mechanism CTD PMID:12559600 NCBI chr 2:104,744,249...104,803,034
Ensembl chr 2:104,744,461...104,799,853 		JBrowse link
G Crp C-reactive protein treatment ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:serum:		 CTD PMID:12559600, PMID:22503884, PMID:22754198 RGD:6482313, RGD:9495927 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713 		JBrowse link
G Csf2 colony stimulating factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:7744320 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070 		JBrowse link
G Csmd1 CUB and Sushi multiple domains 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20953187 NCBI chr16:77,152,823...78,850,222
Ensembl chr16:78,539,489...78,850,222 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 treatment ISO RGD PMID:10974034 RGD:7411683 NCBI chr 9:67,699,397...67,706,068
Ensembl chr 9:67,699,379...67,706,065 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 ISO DNA:SNP, missense mutation:intron, cds: , p.T280M (human) RGD PMID:17002687 RGD:9491384 NCBI chr 8:128,740,756...128,754,514
Ensembl chr 8:128,740,756...128,754,514 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 susceptibility ISO DNA:missense mutation, SNP:exon, 3' utr:2455A>G, 3801T>C (human) RGD PMID:12713578 RGD:5147677 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147 		JBrowse link
G Cyp2s1 cytochrome P450, family 2, subfamily s, polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12711469 NCBI chr 1:82,595,211...82,610,350
Ensembl chr 1:82,595,211...82,610,350 		JBrowse link
G Ddx58 DEXD/H-box helicase 58 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143594 NCBI chr 5:56,486,584...56,536,898
Ensembl chr 5:56,500,734...56,536,772 		JBrowse link
G Dusp1 dual specificity phosphatase 1 ISO mRNA:decreased expression:skin RGD PMID:22924482 RGD:7495852 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418 		JBrowse link
G Eln elastin treatment ISO RGD PMID:6893335 RGD:9585764 NCBI chr12:24,978,478...25,021,864
Ensembl chr12:24,978,483...25,021,863 		JBrowse link
G Epas1 endothelial PAS domain protein 1 ISO RGD PMID:17495954 RGD:10395383 NCBI chr 6:10,306,508...10,385,239
Ensembl chr 6:10,306,405...10,387,265 		JBrowse link
G Erap1 endoplasmic reticulum aminopeptidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20953187, PMID:20953190, PMID:23291587, PMID:24212883 NCBI chr 2:1,410,877...1,449,734
Ensembl chr 2:1,410,934...1,449,733 		JBrowse link
G Fabp5 fatty acid binding protein 5 ISO mRNA:increased expression:skin (human) RGD PMID:16283139 RGD:1578463 NCBI chr 2:93,981,662...93,985,322
Ensembl chr 2:93,981,656...93,985,378 		JBrowse link
G Fbxl19 F-box and leucine-rich repeat protein 19 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20953189 NCBI chr 1:199,196,126...199,217,147
Ensembl chr 1:199,196,059...199,216,391 		JBrowse link
G Fcgr2a Fc fragment of IgG receptor IIa ISO mRNA:increased expression:dermal dendritic cell RGD PMID:20471070 RGD:5147919 NCBI chr13:91,146,878...91,163,691
Ensembl chr13:91,168,973...91,198,036
Ensembl chr13:91,168,973...91,198,036 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 disease_progression ISO protein:increased expression:serum: RGD PMID:20980160 RGD:8552359 NCBI chr12:9,033,993...9,205,886
Ensembl chr12:9,034,308...9,205,905 		JBrowse link
G Gba glucosylceramidase beta ISO RGD PMID:15610510 RGD:5508434 NCBI chr 2:188,511,781...188,522,602
Ensembl chr 2:188,516,582...188,522,601 		JBrowse link
G Gjb2 gap junction protein, beta 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20953187, PMID:24212883 NCBI chr15:37,377,313...37,394,494
Ensembl chr15:37,377,316...37,383,277 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 ISO protein:increased expression:epidermis: RGD PMID:21805023 RGD:5491007 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147 		JBrowse link
G Hcar2 hydroxycarboxylic acid receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18722346 NCBI chr12:38,160,464...38,161,546
Ensembl chr12:38,160,464...38,161,546 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha ISO protein:increased expression:serum (human) RGD PMID:23517877, PMID:17495954 RGD:8695945, RGD:10395383 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052 		JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment
severity		 ISO protein:increased expression:serum RGD PMID:2015706, PMID:8094011, PMID:16181457 RGD:8158118, RGD:8547688, RGD:8547579 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059 		JBrowse link
G Ifih1 interferon induced with helicase C domain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20953190 NCBI chr 3:48,557,696...48,604,097
Ensembl chr 3:48,557,696...48,604,097 		JBrowse link
G Ifnlr1 interferon, lambda receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20953190 NCBI chr 5:154,037,243...154,058,862
Ensembl chr 5:154,037,202...154,058,880 		JBrowse link
G Igf1 insulin-like growth factor 1 ISO mRNA,protein:increased expression:skin: RGD PMID:21241374 RGD:8549492 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta ISO RGD PMID:16397523 RGD:7495754 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815 		JBrowse link
G Il10 interleukin 10 onset ISO DNA:SNP:promoter:-1082G>A (human) RGD PMID:11298547 RGD:7829824 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392 		JBrowse link
G Il12b interleukin 12B ISO CTD Direct Evidence: marker/mechanism CTD PMID:19169254, PMID:19169255, PMID:20953190 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085 		JBrowse link
G Il13 interleukin 13 no_association
susceptibility		 ISO DNA:SNP, missense mutation:promoter, cds:-1112C>T, p.R130Q (rs1800925, rs20541) (human
CTD Direct Evidence: marker/mechanism
DNA:missense mutation:cds: (rs20541) (human)		 CTD PMID:19169254, PMID:20953190, PMID:21349879, PMID:23617596 RGD:8549517, RGD:8549593 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466 		JBrowse link
G Il13ra1 interleukin 13 receptor subunit alpha 1 ISO mRNA:increased expression:skin RGD PMID:14527737 RGD:8549525 NCBI chr  X:122,724,081...122,783,801
Ensembl chr  X:122,724,129...122,781,479 		JBrowse link
G Il17a interleukin 17A treatment ISO mRNA:protein:increased expression:epidermis (human) RGD PMID:24286371, PMID:20926833, PMID:21172868, PMID:23359500, PMID:23359500 RGD:8698656, RGD:9068415, RGD:9068413, RGD:8698663, RGD:8698663 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786 		JBrowse link
G Il18 interleukin 18 treatment ISO protein:increased expression:plasma RGD PMID:22291810, PMID:17611614 RGD:8655900, RGD:8655919 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299 		JBrowse link
G Il1b interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:7744320 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726 		JBrowse link
G Il2 interleukin 2 disease_progression ISO RGD PMID:2448994 RGD:10047079 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854 		JBrowse link
G Il20 interleukin 20 ISO associated with Respiratory Tract Infections;DNA:SNP:enhancer:-1723C>G (rs1713239) (human) RGD PMID:21109726 RGD:5147391 NCBI chr13:47,644,071...47,651,487
Ensembl chr13:47,644,071...47,647,715 		JBrowse link
G Il23a interleukin 23 subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:19169254, PMID:20953190 NCBI chr 7:2,710,609...2,712,723
Ensembl chr 7:2,710,609...2,712,723 		JBrowse link
G Il23r interleukin 23 receptor susceptibility ISO DNA:SNP:cds:p.R381Q(human)
ClinVar Annotator: match by term: Psoriasis, protection against
CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs11805303(human)
DNA:SNPs: :rs1884444,rs10889677(human);		 ClinVar
CTD		 PMID:12023369, PMID:17068223, PMID:17447842, PMID:17587057, PMID:17786191, PMID:17804789, PMID:18438406, PMID:19122664, PMID:19169254, PMID:20228799, PMID:20953190, PMID:24212883, PMID:17587057, PMID:20978829, PMID:23093364 RGD:8549569, RGD:8549602, RGD:8549574 NCBI chr 4:98,203,788...98,306,729
Ensembl chr 4:98,203,958...98,305,173 		JBrowse link
G Il3 interleukin 3 ISO protein: decreased expression RGD PMID:19889595 RGD:5686909 NCBI chr10:39,620,535...39,622,973
Ensembl chr10:39,620,563...39,622,973 		JBrowse link
G Il36rn interleukin 36 receptor antagonist ISO CTD Direct Evidence: marker/mechanism CTD NCBI chr 3:1,385,256...1,392,275
Ensembl chr 3:1,385,654...1,392,275 		JBrowse link
G Il4 interleukin 4 treatment ISO protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism		 CTD PMID:19169254, PMID:15039646, PMID:19729876 RGD:7829812, RGD:7829826 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531 		JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16844318 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 ISO RGD PMID:23018031 RGD:7495784 NCBI chr  X:156,716,469...156,726,367
Ensembl chr  X:156,716,604...156,725,977 		JBrowse link
G Itgb2 integrin subunit beta 2 ISO
ISS		 OMIM:177900 | OMIM:601454 | OMIM:602723 | OMIM:603935 | OMIM:604316 | OMIM:605364 | OMIM:605606 | OMIM:607857 | OMIM:610707 | OMIM:612410 | OMIM:612599 | OMIM:612950 | OMIM:614070 | OMIM:616106 MouseDO PMID:19812597 RGD:6482221 NCBI chr20:11,777,773...11,815,647
Ensembl chr20:11,777,783...11,815,647 		JBrowse link
G Kdr kinase insert domain receptor treatment ISO mRNA:increased expression:skin: RGD PMID:23732650, PMID:20071151 RGD:8552361, RGD:8552376 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183 		JBrowse link
G Lce3e late cornified envelope 3E ISO CTD Direct Evidence: marker/mechanism CTD PMID:19169253 NCBI chr 2:193,275,472...193,276,006
Ensembl chr 2:193,275,507...193,275,803 		JBrowse link
G Lpin2 lipin 2 ISO ClinVar Annotator: match by term: Psoriasis ClinVar PMID:25741868, PMID:28492532 NCBI chr 9:119,517,101...119,591,533
Ensembl chr 9:119,517,101...119,591,533 		JBrowse link
G Lta lymphotoxin alpha susceptibility ISO DNA:SNP:intron:IVS1 (human) RGD PMID:12709814 RGD:8548775 NCBI chr20:4,851,889...4,854,677
Ensembl chr20:4,852,496...4,854,677 		JBrowse link
G Mbl2 mannose binding lectin 2 susceptibility ISO DNA:polymorphism:cds: RGD PMID:23113841 RGD:8693722 NCBI chr 1:248,435,069...248,442,669
Ensembl chr 1:248,723,397...248,729,962 		JBrowse link
G Mki67 marker of proliferation Ki-67 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10384915, PMID:22499302 RGD:6483515 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454 		JBrowse link
G Mydgf myeloid-derived growth factor ISO protein:increased expression:skin (human) RGD PMID:23657503 RGD:39128244 NCBI chr 9:10,885,521...10,892,744
Ensembl chr 9:10,885,560...10,892,405 		JBrowse link
G Nat2 N-acetyltransferase 2 susceptibility ISO DNA:polymorphisms: : RGD PMID:19334527 RGD:8552687 NCBI chr16:23,960,709...23,991,570
Ensembl chr16:23,961,067...23,991,570 		JBrowse link
G Nfkbia NFKB inhibitor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:20953190 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457 		JBrowse link
G Nos2 nitric oxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20953189 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190 		JBrowse link
G Pcna proliferating cell nuclear antigen ISO CTD Direct Evidence: marker/mechanism CTD PMID:10384915 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma ISO CTD Direct Evidence: therapeutic CTD PMID:10815854 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380 		JBrowse link
G Psmb9 proteasome 20S subunit beta 9 ISO RGD PMID:17581627 RGD:6482263 NCBI chr20:3,973,424...3,978,845
Ensembl chr20:3,973,420...3,978,845 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 no_association
susceptibility
onset		 ISO DNA:missense mutation:cds:p.R620W (rs2476601) (human)
DNA:missense mutation:cds:1858C>T (p.R620W) (rs2476601) (human)
DNA:SNP:3' utr: (rs3789604) (human)
DNA:SNPs:intron, 3' utr: (rs1217414, rs3789604) (human)		 RGD PMID:18341666, PMID:20039785, PMID:18923449, PMID:18341666 RGD:7829762, RGD:7829765, RGD:7829764, RGD:7829762 NCBI chr 2:206,342,066...206,390,348
Ensembl chr 2:206,342,066...206,390,348 		JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin ISO CTD Direct Evidence: marker/mechanism CTD PMID:20953187 NCBI chr10:29,014,332...29,026,088
Ensembl chr10:29,020,049...29,026,002 		JBrowse link
G Rel REL proto-oncogene, NF-kB subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:20953190 NCBI chr14:108,490,794...108,517,582
Ensembl chr14:108,491,069...108,509,892 		JBrowse link
G Ren renin ISO CTD Direct Evidence: marker/mechanism CTD PMID:3540694 NCBI chr13:50,502,724...50,513,953
Ensembl chr13:50,502,724...50,514,151 		JBrowse link
G Rnf114 ring finger protein 114 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20953190 NCBI chr 3:164,248,736...164,260,499
Ensembl chr 3:164,248,731...164,260,497 		JBrowse link
G RT1-Ba RT1 class II, locus Ba susceptibility ISO DNA:polymorphisms:cds:HLA-DQA1*0104, HLA-DQA1*0201, HLA-DQA1*0501 (human) RGD PMID:15009387 RGD:5147797 NCBI chr20:4,066,133...4,070,726
Ensembl chr20:4,066,132...4,070,721 		JBrowse link
G RT1-Bb RT1 class II, locus Bb susceptibility ISO DNA:polymorphisms:cds:HLA-DQB1*0201, HLA-DQB1*0303 (human) RGD PMID:15009387 RGD:5147797 NCBI chr20:4,043,726...4,049,367
Ensembl chr20:4,039,413...4,049,711 		JBrowse link
G Runx3 RUNX family transcription factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143594 NCBI chr 5:153,507,093...153,531,137
Ensembl chr 5:153,507,093...153,531,137 		JBrowse link
G Ryr1 ryanodine receptor 1 ISO ClinVar Annotator: match by term: Psoriasis ClinVar PMID:30311386 NCBI chr 1:87,959,596...88,066,252
Ensembl chr 1:87,959,712...88,066,101 		JBrowse link
G S100a7a S100 calcium binding protein A7A ISS OMIM:177900 | OMIM:601454 | OMIM:602723 | OMIM:603935 | OMIM:604316 | OMIM:605364 | OMIM:605606 | OMIM:607857 | OMIM:610707 | OMIM:612410 | OMIM:612599 | OMIM:612950 | OMIM:614070 | OMIM:616106 MouseDO NCBI chr 2:190,058,093...190,063,132
Ensembl chr 2:190,058,093...190,062,534 		JBrowse link
G Serpinb8 serpin family B member 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20953187 NCBI chr13:27,876,662...27,914,038
Ensembl chr13:27,889,345...27,914,006 		JBrowse link
G Sod2 superoxide dismutase 2 ISO mRNA:increased expression:skin:
CTD Direct Evidence: marker/mechanism		 CTD PMID:7744320, PMID:7744320 RGD:8547526 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587 		JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 ISS OMIM:177900 | OMIM:601454 | OMIM:602723 | OMIM:603935 | OMIM:604316 | OMIM:605364 | OMIM:605606 | OMIM:607857 | OMIM:610707 | OMIM:612410 | OMIM:612599 | OMIM:612950 | OMIM:614070 | OMIM:616106 MouseDO NCBI chr 6:111,334,408...111,417,960
Ensembl chr 6:111,339,136...111,417,954 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 treatment ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143594, PMID:23594598, PMID:20811392 RGD:8694295, RGD:8694306 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233 		JBrowse link
G Stat4 signal transducer and activator of transcription 4 susceptibility ISO DNA:SNP:intron:IVS3 (rs7574865) (human) RGD PMID:19500629 RGD:8661715 NCBI chr 9:54,340,649...54,457,753
Ensembl chr 9:54,287,541...54,484,533 		JBrowse link
G Tagap T-cell activation RhoGTPase activating protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143594 NCBI chr 1:47,493,990...47,503,492
Ensembl chr 1:47,493,994...47,502,952 		JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member susceptibility ISO DNA:missense mutation, haplotype:cds:p.I333V (1207A>G) (human) RGD PMID:11194890 RGD:8548788 NCBI chr20:3,979,302...3,989,669
Ensembl chr20:3,979,035...3,989,669 		JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member susceptibility ISO DNA:SNPs:CDs:p.T665A, Q687Q(human) RGD PMID:17581627 RGD:6482263 NCBI chr20:3,995,544...4,009,587
Ensembl chr20:3,995,544...4,009,587 		JBrowse link
G Tgfa transforming growth factor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:7519033 NCBI chr 4:117,961,877...118,045,923
Ensembl chr 4:117,962,319...118,046,344 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 severity ISO protein:increased expression:serum RGD PMID:15072741 RGD:7394851 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199 		JBrowse link
G Tlr2 toll-like receptor 2 ISO mRNA:increased expression:mononuclear cell: RGD PMID:23457721 RGD:7777173 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061 		JBrowse link
G Tlr4 toll-like receptor 4 ISO mRNA:increased expression:mononuclear cell: RGD PMID:23457721 RGD:7777173 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052 		JBrowse link
G Tnf tumor necrosis factor susceptibility ISO DNA:SNP: :-238G>A(rs361525)(human)
CTD Direct Evidence: marker/mechanism		 CTD PMID:7744320, PMID:16844318, PMID:9326391, PMID:16821276 RGD:7394813, RGD:7401180 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19169254, PMID:20953190 NCBI chr 1:14,401,103...14,416,369
Ensembl chr 1:14,402,913...14,412,807 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A treatment ISO RGD PMID:15998370 RGD:8661740 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633 		JBrowse link
G Tnip1 TNFAIP3 interacting protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19169254, PMID:20953190 NCBI chr10:40,255,776...40,303,092
Ensembl chr10:40,255,776...40,296,470 		JBrowse link
G Tp53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10384915 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449 		JBrowse link
G Traf3ip2 Traf3 interacting protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20953186, PMID:20953188, PMID:20953190 NCBI chr20:44,679,861...44,722,874
Ensembl chr20:44,680,449...44,722,872 		JBrowse link
G Ttc7a tetratricopeptide repeat domain 7A ISS OMIM:177900 | OMIM:601454 | OMIM:602723 | OMIM:603935 | OMIM:604316 | OMIM:605364 | OMIM:605606 | OMIM:607857 | OMIM:610707 | OMIM:612410 | OMIM:612599 | OMIM:612950 | OMIM:614070 | OMIM:616106 MouseDO NCBI chr 6:10,912,383...11,014,279
Ensembl chr 6:10,912,383...11,014,278 		JBrowse link
G Tyk2 tyrosine kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20953190 NCBI chr 8:22,118,224...22,149,807
Ensembl chr 8:22,124,560...22,150,005 		JBrowse link
G Vdr vitamin D receptor treatment
no_association
susceptibility		 ISO DNA:silent mutation:cds:pI352 (rs731236) (human)
DNA:SNPs, haplotype:promoter, exon:-1012A>G, (rs731236, rs2228570) (human)
DNA:SNPs:intron, cds: (rs731236, rs1544410, rs7975232) (human)
DNA:SNPs, haplotype:intron, cds, enhancer:multiple
DNA:SNPs:exon:multiple
DNA:SNP:promoter:-1012A>G (rs4516035) (human)
DNA:silent mutation:cds: (rs731236) (human)		 GAD
RGD		 PMID:15118671, PMID:20716226, PMID:15864137, PMID:21951018, PMID:24055231, PMID:24320988, PMID:24320988, PMID:17763859 RGD:1331525, RGD:8158081, RGD:8158072, RGD:8158062, RGD:8158056, RGD:8157635, RGD:8157635, RGD:8157633 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166 		JBrowse link
G Vegfa vascular endothelial growth factor A onset
disease_progression
treatment		 ISO mRNA:increased expression:skin:
CTD Direct Evidence: marker/mechanism
DNA:polymorphism: :405C>G(human)
protein:increased expression:serum:		 CTD PMID:16385345, PMID:8064230, PMID:14962110, PMID:20980160, PMID:19995970 RGD:7421592, RGD:8552645, RGD:8552359, RGD:8549646 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681 		JBrowse link
G Vnn1 vanin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19322213 NCBI chr 1:22,614,832...22,625,134
Ensembl chr 1:22,614,783...22,625,204 		JBrowse link
G Vnn3 vanin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19322213 NCBI chr 1:22,649,114...22,661,376
Ensembl chr 1:22,649,081...22,661,377 		JBrowse link
G Zc3h12c zinc finger CCCH type containing 12C ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143594 NCBI chr 8:56,639,439...56,696,968
Ensembl chr 8:56,641,808...56,696,968 		JBrowse link
G Zfp141 zinc finger protein 141 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20953187, PMID:24212883 NCBI chr 1:98,168,457...98,201,189 JBrowse link
psoriasis 12 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rnf114 ring finger protein 114 susceptibility ISO OMIM NCBI chr 3:164,248,736...164,260,499
Ensembl chr 3:164,248,731...164,260,497 		JBrowse link
psoriasis 13 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Traf3ip2 Traf3 interacting protein 2 susceptibility ISO ClinVar Annotator: match by term: Psoriasis susceptibility 13 ClinVar
OMIM		 PMID:20953186, PMID:20953188, PMID:22581863, PMID:24033266, PMID:24120361 NCBI chr20:44,679,861...44,722,874
Ensembl chr20:44,680,449...44,722,872 		JBrowse link
psoriasis 15 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap1s3 adaptor related protein complex 1 subunit sigma 3 susceptibility ISO ClinVar Annotator: match by term: Psoriasis 15, pustular, susceptibility to ClinVar
OMIM		 PMID:24033266, PMID:24791904 NCBI chr 9:85,386,752...85,445,977
Ensembl chr 9:85,387,065...85,445,939 		JBrowse link
psoriasis 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Card14 caspase recruitment domain family, member 14 ISO ClinVar Annotator: match by term: Psoriasis susceptibility 2 OMIM
ClinVar		 PMID:8178173, PMID:15689454, PMID:18256691, PMID:22521418, PMID:22521419, PMID:23648549, PMID:29477734 NCBI chr10:108,440,480...108,469,012
Ensembl chr10:108,440,950...108,468,310 		JBrowse link
psoriasis 7 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il23r interleukin 23 receptor susceptibility ISO OMIM NCBI chr 4:98,203,788...98,306,729
Ensembl chr 4:98,203,958...98,305,173 		JBrowse link
psoriatic arthritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20008919 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 ISO protein:increased expression:serum RGD PMID:16936328 RGD:5683894 NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 susceptibility ISO associated with Psoriasis;DNA:SNP:p.V64I(rs1799864)(human) RGD PMID:20153665 RGD:8661745
G Cd68 Cd68 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:19732956 NCBI chr10:56,268,726...56,270,605
Ensembl chr10:56,268,720...56,270,640 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 susceptibility ISO DNA:polymorphisms: :4887C>A, 4889A>G (human) RGD PMID:15124938 RGD:5147746 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147 		JBrowse link
G Fbxl19 F-box and leucine-rich repeat protein 19 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20953189 NCBI chr 1:199,196,126...199,217,147
Ensembl chr 1:199,196,059...199,216,391 		JBrowse link
G Il12b interleukin 12B ISO CTD Direct Evidence: marker/mechanism CTD PMID:20953186 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085 		JBrowse link
G Il13 interleukin 13 susceptibility ISO DNA:SNP, missense mutation:promoter, cds:-1112C>T, p.R130Q (rs1800925, rs20541) (human
DNA:SNPs:promoter, exon:rs1800925, rs20541, rs848 (human)		 RGD PMID:21349879, PMID:19554022 RGD:8549517, RGD:8549552 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466 		JBrowse link
G Il17a interleukin 17A severity
treatment		 ISO RGD PMID:24567524, PMID:23361084 RGD:8698658, RGD:9068444 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 susceptibility ISO DNA:SNP:enhancer: (rs3027898) (human) RGD PMID:20500689 RGD:7495783 NCBI chr  X:156,716,469...156,726,367
Ensembl chr  X:156,716,604...156,725,977 		JBrowse link
G Lta lymphotoxin alpha treatment
susceptibility		 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by OMIM:607507		 OMIM
CTD
ClinVar		 PMID:12426569, PMID:12746914, PMID:14681301, PMID:22480318 RGD:8548821 NCBI chr20:4,851,889...4,854,677
Ensembl chr20:4,852,496...4,854,677 		JBrowse link
G Mefv MEFV innate immuity regulator, pyrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:17408446 NCBI chr10:12,045,813...12,056,229
Ensembl chr10:12,046,541...12,056,311 		JBrowse link
G Mmp1 matrix metallopeptidase 1 ISO protein:increased expression:plasma (human) RGD PMID:9972954 RGD:7207129 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591 		JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO RGD PMID:11796404 RGD:7241254 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579 		JBrowse link
G Nos2 nitric oxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20953189 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190 		JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19732956 NCBI chr 3:43,111,258...43,128,391
Ensembl chr 3:43,111,240...43,119,159 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 ISO RGD PMID:22751595 RGD:6771221 NCBI chr10:94,850,971...94,913,202 JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 no_association ISO DNA: snp: cds: rs2476601
DNA:missense mutation: :R620W (rs2476601) (human)		 RGD PMID:21410964, PMID:15934099 RGD:6484592, RGD:6484550 NCBI chr 2:206,342,066...206,390,348
Ensembl chr 2:206,342,066...206,390,348 		JBrowse link
G Runx2 RUNX family transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20008919 NCBI chr 9:18,564,743...18,773,092
Ensembl chr 9:18,564,927...18,773,092 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 no_association ISO DNA:SNP: :rs744166 (human)
DNA:SNP: :rs2293152 (human)		 RGD PMID:23127549, PMID:23127549 RGD:8694309, RGD:8694309 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233 		JBrowse link
G Stat4 signal transducer and activator of transcription 4 ISO DNA:SNP: :rs10181656 (human) RGD PMID:22328738 RGD:8661724 NCBI chr 9:54,340,649...54,457,753
Ensembl chr 9:54,287,541...54,484,533 		JBrowse link
G Tnf tumor necrosis factor susceptibility ISO DNA:SNP: :-238G>A(rs361525)(human)
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Psoriatic arthritis, susceptibility to		 CTD
ClinVar		 PMID:8056188, PMID:9818939, PMID:10450718, PMID:11261930, PMID:11506397, PMID:11826025, PMID:11896460, PMID:12485196, PMID:12746914, PMID:14681301, PMID:14718719, PMID:16418737, PMID:16865291, PMID:19732956, PMID:9326391 RGD:7394813 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Traf3ip2 Traf3 interacting protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20953186, PMID:20953188 NCBI chr20:44,679,861...44,722,874
Ensembl chr20:44,680,449...44,722,872 		JBrowse link
pustular psoriasis 14 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1f10 interleukin 1 family member 10 ISO ClinVar Annotator: match by term: Pustular psoriasis, generalized ClinVar PMID:21848462, PMID:28492532 NCBI chr 3:1,408,560...1,416,601
Ensembl chr 3:1,413,671...1,416,599 		JBrowse link
G Il36rn interleukin 36 receptor antagonist ISO ClinVar Annotator: match by term: Pustular psoriasis, generalized OMIM
ClinVar		 PMID:21839423, PMID:21848462, PMID:22428995, PMID:22903787, PMID:23303454, PMID:23358093, PMID:23428889, PMID:23648549, PMID:23698098, PMID:23792462, PMID:23834760, PMID:23863864, PMID:24033266, PMID:24898045, PMID:24979538, PMID:25212972, PMID:25427108, PMID:25458002, PMID:25468355, PMID:25615897, PMID:25741868, PMID:25989471, PMID:26147717, PMID:26589685, PMID:26676204, PMID:27096382, PMID:27220475, PMID:27388993, PMID:27542682, PMID:28063630, PMID:28492532, PMID:28887889, PMID:30036598 NCBI chr 3:1,385,256...1,392,275
Ensembl chr 3:1,385,654...1,392,275 		JBrowse link
pustulosis of palm and sole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lta lymphotoxin alpha ISO DNA:SNP:intron:IVS1 (human) RGD PMID:12691703 RGD:8548804 NCBI chr20:4,851,889...4,854,677
Ensembl chr20:4,852,496...4,854,677 		JBrowse link
G Tnf tumor necrosis factor no_association ISO DNA:SNPs:promoter:multiple
DNA:SNPs, haplotype:5' utr:multiple		 RGD PMID:11019918, PMID:12691703 RGD:8548803, RGD:8548804 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
vitiligo term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bach2 BTB domain and CNC homolog 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22561518 NCBI chr 5:47,458,891...47,807,176
Ensembl chr 5:47,546,014...47,807,166 		JBrowse link
G C3 complement C3 ISO RGD PMID:12121667 RGD:7401277 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167 		JBrowse link
G C4a complement C4A ISO associated with Graves Disease RGD PMID:21943165 RGD:5688264 NCBI chr20:2,651,599...2,678,183
Ensembl chr20:2,651,599...2,678,141 		JBrowse link
G Casp7 caspase 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22561518 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774 		JBrowse link
G Cat catalase susceptibility
no_association		 ISO DNA:SNP,haplotype:promoter,cds:-89A>T,389C>T(human)
protein:decreased activity:skin:
DNA:SNPs:promoter,exon: -89A>T rs7943316), 389C>T (rs769217)(human) 		RGD PMID:20613769, PMID:19439879, PMID:23868633 RGD:9479149, RGD:9479169, RGD:9479150 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058 		JBrowse link
G Ccr6 C-C motif chemokine receptor 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20526340 NCBI chr 1:53,063,380...53,087,519
Ensembl chr 1:53,065,025...53,087,474 		JBrowse link
G Cd44 CD44 molecule (Indian blood group) ISO CTD Direct Evidence: marker/mechanism CTD PMID:22561518 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658 		JBrowse link
G Cd80 Cd80 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:22561518 NCBI chr11:64,815,201...64,855,293
Ensembl chr11:64,827,635...64,855,353 		JBrowse link
G Clnk cytokine-dependent hematopoietic cell linker ISO CTD Direct Evidence: marker/mechanism CTD PMID:22561518 NCBI chr14:76,657,165...76,834,050
Ensembl chr14:76,657,311...76,833,161 		JBrowse link
G Clu clusterin ISO RGD PMID:7558712 RGD:8699503 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857 		JBrowse link
G Comt catechol-O-methyltransferase no_association ISO DNA:polymorphism: :p.V158M (human) RGD PMID:19112571, PMID:24915010 RGD:8662333, RGD:8662336 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 susceptibility
no_association		 ISO associated with Autoimmune Diseases;DNA:polymorphisms: :
DNA:SNP:exon:+49A>G rs231775)(human)
DNA:SNPs:multiple:
DNA:SNP:3'UTR:rs3087243(human)		 RGD PMID:15649153, PMID:19129082, PMID:18200060, PMID:21794098 RGD:7411687, RGD:7411699, RGD:7411697, RGD:7411696 NCBI chr 9:67,699,397...67,706,068
Ensembl chr 9:67,699,379...67,706,065 		JBrowse link
G Esr1 estrogen receptor 1 susceptibility
no_association		 ISO DNA:SNP:intron
DNA:SNP:exon		 RGD PMID:15381239, PMID:15381239 RGD:8552976, RGD:8552976 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796 		JBrowse link
G Foxd3 forkhead box D3 susceptibility ISO ClinVar Annotator: match by OMIM:607836
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
OMIM		 PMID:16098053 NCBI chr 5:118,346,283...118,349,120 JBrowse link
G Foxp1 forkhead box P1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20526340 NCBI chr 4:131,362,178...131,963,466
Ensembl chr 4:131,366,744...131,694,755 		JBrowse link
G Hgf hepatocyte growth factor treatment ISO RGD PMID:16117796 RGD:8548598 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A treatment ISO RGD PMID:23447019 RGD:8662840 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779 		JBrowse link
G Ifih1 interferon induced with helicase C domain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22561518 NCBI chr 3:48,557,696...48,604,097
Ensembl chr 3:48,557,696...48,604,097 		JBrowse link
G Ifng interferon gamma susceptibility
onset		 ISO DNA:repeats:intron:rs3138557(human)
DNA:polymorphism:intron:rs2430561(human)		 RGD PMID:23777204, PMID:23777204 RGD:8157616, RGD:8157616 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419 		JBrowse link
G Ikzf4 IKAROS family zinc finger 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22561518 NCBI chr 7:3,061,422...3,098,142
Ensembl chr 7:3,061,469...3,074,359 		JBrowse link
G Il13 interleukin 13 treatment ISO RGD PMID:23680073 RGD:8549591 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466 		JBrowse link
G Il17a interleukin 17A ISO protein:increased expression:serum: RGD PMID:22342018 RGD:8663475 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786 		JBrowse link
G Il1a interleukin 1 alpha ISO protein:increased expression:skin
CTD Direct Evidence: marker/mechanism		 CTD PMID:28836394, PMID:16911396 RGD:7794736 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086 		JBrowse link
G Il2 interleukin 2 ISO protein:increased expression:serum: RGD PMID:22342018 RGD:8663475 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854 		JBrowse link
G Il4 interleukin 4 ISO protein:increased expression:serum: RGD PMID:22342018 RGD:8663475 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531 		JBrowse link
G Kif1b kinesin family member 1B ISO ClinVar Annotator: match by term: Vitiligo ClinVar PMID:25741868 NCBI chr 5:165,994,803...166,133,497
Ensembl chr 5:165,938,576...166,133,491 		JBrowse link
G Mbl2 mannose binding lectin 2 susceptibility
no_association		 ISO DNA:polymorphism:exon:
DNA:polymorphisms:promoter, exon:		 RGD PMID:17337399, PMID:19416237 RGD:8693723, RGD:8693724 NCBI chr 1:248,435,069...248,442,669
Ensembl chr 1:248,723,397...248,729,962 		JBrowse link
G Mc1r melanocortin 1 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:22561518 NCBI chr19:56,215,420...56,219,987 JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28836394 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996 		JBrowse link
G Nlrp1a NLR family, pyrin domain containing 1A susceptibility ISO ClinVar Annotator: match by term: Vitiligo-associated multiple autoimmune disease susceptibility 1
CTD Direct Evidence: marker/mechanism		 OMIM
ClinVar
CTD		 PMID:17377159 NCBI chr10:57,692,474...57,747,608
Ensembl chr10:57,692,474...57,822,498 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28836394 NCBI chr 2:31,742,326...31,826,882
Ensembl chr 2:31,745,088...31,826,867 		JBrowse link
G Psmb9 proteasome 20S subunit beta 9 ISO RGD PMID:14551602 RGD:1578358 NCBI chr20:3,973,424...3,978,845
Ensembl chr20:3,973,420...3,978,845 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 ISO DNA: snp : cds: rs2476601
DNA:polymorphism: :1858C>T (p.R620W) (human)		 RGD PMID:16015369, PMID:18426414 RGD:6484552, RGD:7829737 NCBI chr 2:206,342,066...206,390,348
Ensembl chr 2:206,342,066...206,390,348 		JBrowse link
G RT1-Ba RT1 class II, locus Ba susceptibility ISO DNA:polymorphisms:: HLA-DQA1*0302, HLA-DQA1*0601, HLA-DQA1*0501; RGD PMID:16409268 RGD:8547566 NCBI chr20:4,066,133...4,070,726
Ensembl chr20:4,066,132...4,070,721 		JBrowse link
G RT1-Bb RT1 class II, locus Bb susceptibility ISO DNA:polymorphisms (human)
DNA:polymorphism:HLA-DQB1*0201(human)		 RGD PMID:16420246, PMID:9653015 RGD:5147644, RGD:36174006 NCBI chr20:4,043,726...4,049,367
Ensembl chr20:4,039,413...4,049,711 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 susceptibility ISO DNA:polymorphisms (human)
DNA:polymorphism: : HLA-DRB1*0701(human)		 RGD PMID:16420246, PMID:9653015 RGD:5147644, RGD:36174006 NCBI chr20:4,087,621...4,097,190
Ensembl chr20:4,087,618...4,097,190 		JBrowse link
G Sh2b3 SH2B adaptor protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22561518 NCBI chr12:40,261,990...40,265,757
Ensembl chr12:40,244,081...40,265,757 		JBrowse link
G Sla src-like adaptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:22561518 NCBI chr 7:107,585,055...107,604,950
Ensembl chr 7:107,584,118...107,634,335 		JBrowse link
G Sod2 superoxide dismutase 2 disease_progression ISO DNA, mRNA, protein:SNPs, increased expression:cds:p.L84F (rs11575993), p.T58I (rs35289490), skin, leukocyte (human) RGD PMID:24036105 RGD:8547522 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO protein:decreased expression:serum: RGD PMID:22342018 RGD:8663475 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199 		JBrowse link
G Tlr2 toll-like receptor 2 susceptibility ISO DNA:polymorphism:exon:p.R753Q(human) RGD PMID:22429552 RGD:7777152 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061 		JBrowse link
G Tlr4 toll-like receptor 4 susceptibility ISO DNA:polymorphism:exon:p.D299G(human) RGD PMID:22429552 RGD:7777152 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052 		JBrowse link
G Tnf tumor necrosis factor ISO protein:increased expression:skin
CTD Direct Evidence: marker/mechanism		 CTD PMID:28836394, PMID:16911396 RGD:7794736 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Tob2 transducer of ERBB2, 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22561518 NCBI chr 7:123,079,520...123,088,240
Ensembl chr 7:123,079,537...123,088,279 		JBrowse link
G Tyr tyrosinase severity ISO RGD PMID:22834951, PMID:8697641 RGD:8694387, RGD:8694409 NCBI chr 1:151,012,598...151,106,802
Ensembl chr 1:151,012,598...151,106,802 		JBrowse link
G Vdr vitamin D receptor no_association ISO DNA:SNPs, haplotype: :multiple
DNA:SNP:exon:rs2228570 (human)
DNA:SNPs: :rs731236, rs1544410, rs7975232 (human)		 RGD PMID:22738935, PMID:22762534, PMID:22762534 RGD:8158061, RGD:8158066, RGD:8158066 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166 		JBrowse link
Vogt-Koyanagi-Harada disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma ISO associated with uveitis;protein:increased expression:aqueous humor: RGD PMID:21334264 RGD:8142356 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419 		JBrowse link
G Itgb2 integrin subunit beta 2 ISO protein:decreased expression:T cell RGD PMID:21297967 RGD:6482200 NCBI chr20:11,777,773...11,815,647
Ensembl chr20:11,777,783...11,815,647 		JBrowse link
G RT1-Ba RT1 class II, locus Ba susceptibility ISO DNA:polymorphism: : HLA-DQA1*0301 RGD PMID:11835809 RGD:8547565 NCBI chr20:4,066,133...4,070,726
Ensembl chr20:4,066,132...4,070,721 		JBrowse link
G RT1-Bb RT1 class II, locus Bb susceptibility ISO DNA:polymorphisms:cds:multiple (human)
DNA:snps:promoter:g.-227G>A, g.-189C>A (human)		 RGD PMID:17605936, PMID:19176112 RGD:7421525, RGD:7421581 NCBI chr20:4,043,726...4,049,367
Ensembl chr20:4,039,413...4,049,711 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 susceptibility ISO DNA:polymorphism (human)
DNA:polymorphism: :HLA-DRB1*0405(human)
DNA:polymorphisms: :HLA-DRB1*0405, HLA-DRB1*0410(human)
DNA:polymorphisms (human)		 RGD PMID:15603876, PMID:9548078, PMID:20216938, PMID:10527396 RGD:5147653, RGD:7365099, RGD:7365067, RGD:5147857 NCBI chr20:4,087,621...4,097,190
Ensembl chr20:4,087,618...4,097,190 		JBrowse link
G Stat4 signal transducer and activator of transcription 4 ISO DNA:SNP: :rs7574865 (human) RGD PMID:20438790 RGD:8661713 NCBI chr 9:54,340,649...54,457,753
Ensembl chr 9:54,287,541...54,484,533 		JBrowse link
G Tnf tumor necrosis factor ISO associated with uveitis;protein:increased expression:aqueous humor: RGD PMID:21334264 RGD:8142356 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16023
    sensory system disease 5231
      skin disease 2765
        autoimmune disease of skin and connective tissue 182
          Vogt-Koyanagi-Harada disease 7
          alopecia areata + 26
          bullous pemphigoid 8
          dermatitis herpetiformis + 4
          epidermolysis bullosa acquisita 0
          pemphigoid gestationis 0
          pemphigus gestationis 0
          psoriasis + 133
          psoriatic arthritis 23
          vitiligo + 47
Path 2
Term Annotations click to browse term
  disease 16023
    disease of anatomical entity 15278
      Immune & Inflammatory Diseases 3513
        immune system disease 2927
          primary immunodeficiency disease 2344
            autoimmune disease 1663
              autoimmune disease of musculoskeletal system 935
                autoimmune disease of skin and connective tissue 182
                  Vogt-Koyanagi-Harada disease 7
                  alopecia areata + 26
                  bullous pemphigoid 8
                  dermatitis herpetiformis + 4
                  epidermolysis bullosa acquisita 0
                  pemphigoid gestationis 0
                  pemphigus gestationis 0
                  psoriasis + 133
                  psoriatic arthritis 23
                  vitiligo + 47
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.