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ONTOLOGY REPORT - ANNOTATIONS


Term:anaplastic large cell lymphoma
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Accession:DOID:0050744 term browser browse the term
Definition:A systemic, large-cell, non-Hodgkin, malignant lymphoma characterized by cells with pleomorphic appearance and expressing the CD30 ANTIGEN. These so-called 'hallmark' cells have lobulated and indented nuclei. This lymphoma is often mistaken for metastatic carcinoma and MALIGNANT HISTIOCYTOSIS.
Synonyms:exact_synonym: Anaplastic Large-Cell Lymphomas;   CD30 Positive Anaplastic Large Cell Lymphoma;   CD30+ Anaplastic Large Cell Lymphoma;   Ki 1 Lymphoma;   Ki-1 Lymphomas;   Lymphoma, Large-Cell, Ki-1;   Systemic Anaplastic Large Cell Lymphoma
 primary_id: MESH:D017728;   RDO:0007075
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anaplastic large cell lymphoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alk ALK receptor tyrosine kinase JBrowse link 6 22,696,415 23,203,791 RGD:1600902
RGD:11554173
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 JBrowse link 6 135,107,262 135,112,793 RGD:11554173
G Irf4 interferon regulatory factor 4 JBrowse link 17 34,886,746 34,905,191 RGD:11526155
G Junb JunB proto-oncogene, AP-1 transcription factor subunit JBrowse link 19 26,092,972 26,094,756 RGD:1549449
G Npm1 nucleophosmin 1 JBrowse link 10 18,080,949 18,091,062 RGD:1600902
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:11554173
G Twist1 twist family bHLH transcription factor 1 JBrowse link 6 53,401,241 53,403,235 RGD:11554173

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15603
    disease of cellular proliferation 5804
      Neoplasms by Histologic Type 3586
        lymphoma 350
          non-Hodgkin lymphoma 300
            anaplastic large cell lymphoma 7
Path 2
Term Annotations click to browse term
  disease 15603
    disease of anatomical entity 14934
      Hemic and Lymphatic Diseases 1724
        hematopoietic system disease 1452
          Hematologic Neoplasms 790
            hematologic cancer 789
              lymphoma 350
                non-Hodgkin lymphoma 300
                  T-Cell Lymphoma 87
                    anaplastic large cell lymphoma 7
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.