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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:small cell carcinoma
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Accession:DOID:0050685 term browser browse the term
Definition:A carcinoma that is an undifferentiated neoplasm composed of primitive-appearing cells. (DO)
Synonyms:exact_synonym: SCCL;   SCLC;   SCLC1;   oat cell carcinoma;   oat cell carcinomas;   small cell carcinoma, intermediate cell;   small cell carcinomas
 narrow_synonym: Salivary Gland Small Cell Carcinoma
 primary_id: MESH:D018288
 alt_id: OMIM:182280
 xref: EFO:0008524;   EFO:1000519;   NCI:C4099


show annotations for term's descendants           Sort by:
small cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Birc5 baculoviral IAP repeat-containing 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15981204 NCBI chr11:117,740,063...117,746,569
Ensembl chr11:117,740,077...117,746,569 		JBrowse link
G Chi3l1 chitinase 3 like 1 severity ISO protein:increased secretion:serum (human) RGD PMID:15541818 RGD:4892640 NCBI chr 1:134,109,894...134,117,769
Ensembl chr 1:134,109,914...134,117,919 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3, cardiac ISO RGD PMID:20150622 RGD:5133439 NCBI chr13:9,925,522...10,411,131
Ensembl chr13:9,925,522...10,410,883 		JBrowse link
G Cyp2a5 cytochrome P450, family 2, subfamily a, polypeptide 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17549345 NCBI chr 7:26,534,764...26,542,689
Ensembl chr 7:26,534,730...26,542,973 		JBrowse link
G Ikzf3 IKAROS family zinc finger 3 ISO protein:increased expression:lung (human) RGD PMID:24823637 RGD:151347636 NCBI chr11:98,355,436...98,437,157
Ensembl chr11:98,355,728...98,436,857 		JBrowse link
G Il6 interleukin 6 disease_progression ISO protein:increased expression:serum RGD PMID:20592377 RGD:4143263 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Mtor mechanistic target of rapamycin kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20946520 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140 		JBrowse link
G Nppa natriuretic peptide type A ISO CTD Direct Evidence: therapeutic CTD PMID:18717826 NCBI chr 4:148,085,179...148,086,531
Ensembl chr 4:148,085,179...148,086,536 		JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 susceptibility ISO DNA:SNP:exon:609C>T (human) RGD PMID:11679176 RGD:5135003 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838 		JBrowse link
G Pycard PYD and CARD domain containing ISO CTD Direct Evidence: marker/mechanism CTD PMID:16778195 NCBI chr 7:127,590,545...127,593,039
Ensembl chr 7:127,588,880...127,593,039 		JBrowse link
G Rassf1 Ras association (RalGDS/AF-6) domain family member 1 ISO RGD PMID:12222680 RGD:2291977 NCBI chr 9:107,428,752...107,439,460
Ensembl chr 9:107,428,754...107,439,466 		JBrowse link
G Rb1 RB transcriptional corepressor 1 ISO CTD Direct Evidence: marker/mechanism OMIM
CTD		 NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262 		JBrowse link
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24658001 PMID:24658002 PMID:24658004 PMID:26343384 NCBI chr 9:21,527,377...21,615,526
Ensembl chr 9:21,527,465...21,615,526 		JBrowse link
G Tert telomerase reverse transcriptase susceptibility ISO DNA:SNP: :rs2736098(human) RGD PMID:24761905 RGD:150530628 NCBI chr13:73,775,030...73,797,962
Ensembl chr13:73,775,030...73,797,962 		JBrowse link
G Tnf tumor necrosis factor severity ISO protein:decreased secretion:whole blood RGD PMID:8624296 RGD:4142840 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Tnfsf10 tumor necrosis factor (ligand) superfamily, member 10 ISO RGD PMID:16313792 RGD:2312747 NCBI chr 3:27,371,226...27,393,814
Ensembl chr 3:27,371,177...27,396,576 		JBrowse link
G Trp53 transformation related protein 53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17290066 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20946520 NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719 		JBrowse link
G Wif1 Wnt inhibitory factor 1 ISO protein:decreased expression:lung RGD PMID:14517837 RGD:727214 NCBI chr10:120,869,909...120,936,547
Ensembl chr10:120,869,865...120,936,555 		JBrowse link
esophagus small cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Krt14 keratin 14 ISO protein:increased expression:esophagus RGD PMID:16140947 RGD:1600174 NCBI chr11:100,093,988...100,098,336
Ensembl chr11:100,093,988...100,098,374 		JBrowse link
lung oat cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 thymoma viral proto-oncogene 1 ISO ClinVar Annotator: match by term: Lung oat cell carcinoma ClinVar PMID:17611497 PMID:18256540 PMID:18392055 PMID:18504432 PMID:18611285 More... NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318 		JBrowse link
G B2m beta-2 microglobulin ISO ClinVar Annotator: match by term: Lung oat cell carcinoma ClinVar PMID:26619011 NCBI chr 2:121,978,168...121,983,563
Ensembl chr 2:121,978,167...121,983,564 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO ClinVar Annotator: match by term: Lung oat cell carcinoma ClinVar PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More... NCBI chr 3:32,451,203...32,520,256
Ensembl chr 3:32,451,820...32,522,635 		JBrowse link
G Pten phosphatase and tensin homolog ISO ClinVar Annotator: match by term: Lung oat cell carcinoma ClinVar PMID:1945792 PMID:9467011 PMID:9915974 PMID:10866302 PMID:11051241 More... NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560 		JBrowse link
G Rb1 RB transcriptional corepressor 1 ISO ClinVar Annotator: match by term: Lung oat cell carcinoma ClinVar PMID:1352883 PMID:7881418 PMID:9632788 PMID:9671401 PMID:10486322 More... NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262 		JBrowse link
G Trp53 transformation related protein 53 ISO ClinVar Annotator: match by term: Lung oat cell carcinoma ClinVar PMID:1359493 PMID:1565143 PMID:1565144 PMID:1569604 PMID:1631137 More... NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
lung small cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1b activin A receptor, type 1B ISO RGD PMID:33880365 RGD:151665493 NCBI chr15:101,071,953...101,111,565
Ensembl chr15:101,071,948...101,111,565 		JBrowse link
G Adcy1 adenylate cyclase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr11:7,013,433...7,128,506
Ensembl chr11:7,013,489...7,128,506 		JBrowse link
G Akt1 thymoma viral proto-oncogene 1 ISO ClinVar Annotator: match by term: Small cell lung cancer ClinVar PMID:17611497 PMID:18256540 PMID:18392055 PMID:18504432 PMID:18611285 More... NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318 		JBrowse link
G Apoa1 apolipoprotein A-I treatment ISO RGD PMID:26996551 RGD:11561502 NCBI chr 9:46,139,928...46,141,767
Ensembl chr 9:46,139,878...46,141,764 		JBrowse link
G Apoc3 apolipoprotein C-III treatment ISO RGD PMID:26996551 RGD:11561502 NCBI chr 9:46,144,348...46,146,934
Ensembl chr 9:46,144,231...46,146,934 		JBrowse link
G Ascl1 achaete-scute family bHLH transcription factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26253517 NCBI chr10:87,326,681...87,329,522
Ensembl chr10:87,326,681...87,329,522 		JBrowse link
G Atm ataxia telangiectasia mutated susceptibility ISO DNA:SNP:intron:(rs227060) (human) RGD PMID:28642860 RGD:150383339 NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040 		JBrowse link
G Atrx ATRX, chromatin remodeler disease_progression ISO RGD PMID:31374064 PMID:29748005 RGD:127285382, RGD:127285383 NCBI chr  X:104,841,221...104,972,978
Ensembl chr  X:104,841,221...104,973,009 		JBrowse link
G Avp arginine vasopressin ISO CTD Direct Evidence: marker/mechanism CTD PMID:2832203 NCBI chr 2:130,422,540...130,424,508
Ensembl chr 2:130,422,540...130,424,474 		JBrowse link
G Axin2 axin 2 disease_progression ISO DNA:SNP::1386 C>T(human) RGD PMID:30346805 RGD:151356655 NCBI chr11:108,808,687...108,841,609
Ensembl chr11:108,811,175...108,841,609 		JBrowse link
G B2m beta-2 microglobulin ISO ClinVar Annotator: match by term: Small cell lung carcinoma ClinVar PMID:26619011 NCBI chr 2:121,978,168...121,983,563
Ensembl chr 2:121,978,167...121,983,564 		JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 susceptibility ISO DNA:SNP: :rs2279115(human) RGD PMID:26311051 RGD:13673911 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004 		JBrowse link
G Bclaf1 BCL2-associated transcription factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr10:20,187,897...20,218,390
Ensembl chr10:20,188,215...20,220,359 		JBrowse link
G Ccnd1 cyclin D1 disease_progression ISO DNA:snp:exon:c.870G>A (human) RGD PMID:29739297 RGD:13673912 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662 		JBrowse link
G Cdkn1b cyclin dependent kinase inhibitor 1B ISO protein:increased expression:lung RGD PMID:9500468 RGD:13673920 NCBI chr 6:134,897,364...134,902,488
Ensembl chr 6:134,897,364...134,902,476 		JBrowse link
G Cdyl chromodomain protein, Y chromosome-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr13:35,843,801...36,058,047
Ensembl chr13:35,843,816...36,058,046 		JBrowse link
G Chrna3 cholinergic receptor, nicotinic, alpha polypeptide 3 susceptibility ISO mRNA:increased expression:lung
DNA:SNP:cds:rs8040868(human)		 RGD PMID:20124469 PMID:22280835 RGD:150527851, RGD:151347453 NCBI chr 9:54,917,401...54,933,846
Ensembl chr 9:54,917,395...54,933,846 		JBrowse link
G Chrna5 cholinergic receptor, nicotinic, alpha polypeptide 5 ISO mRNA:increased expression:lung RGD PMID:20124469 RGD:150527851 NCBI chr 9:54,888,112...54,918,704
Ensembl chr 9:54,888,164...54,915,063 		JBrowse link
G Chrna9 cholinergic receptor, nicotinic, alpha polypeptide 9 susceptibility ISO DNA:SNPs:multiples: RGD PMID:22280835 RGD:151347453 NCBI chr 5:66,092,317...66,134,823
Ensembl chr 5:66,092,264...66,134,669 		JBrowse link
G Chrnb4 cholinergic receptor, nicotinic, beta polypeptide 4 ISO mRNA:increased expression:lung RGD PMID:20124469 RGD:150527851 NCBI chr 9:54,935,438...54,956,236
Ensembl chr 9:54,935,438...54,956,063 		JBrowse link
G Ckb creatine kinase, brain ISO CTD Direct Evidence: marker/mechanism CTD PMID:2828370 NCBI chr12:111,635,789...111,638,772
Ensembl chr12:111,635,795...111,638,772 		JBrowse link
G Cntnap2 contactin associated protein-like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr 6:45,036,995...47,278,330
Ensembl chr 6:45,036,291...47,281,147 		JBrowse link
G Col22a1 collagen, type XXII, alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr15:71,667,644...71,906,087
Ensembl chr15:71,667,644...71,906,076 		JBrowse link
G Col4a2 collagen, type IV, alpha 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr 8:11,362,878...11,499,287
Ensembl chr 8:11,362,805...11,499,287 		JBrowse link
G Crebbp CREB binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941188 NCBI chr16:3,899,198...4,031,864
Ensembl chr16:3,899,192...4,031,861 		JBrowse link
G Csf1r colony stimulating factor 1 receptor exacerbates ISO protein:increased expression:lung (human) RGD PMID:1390197 RGD:150524305 NCBI chr18:61,238,644...61,264,211
Ensembl chr18:61,233,670...61,265,221 		JBrowse link
G Csf3 colony stimulating factor 3 (granulocyte) ISO CTD Direct Evidence: therapeutic CTD PMID:9093707 NCBI chr11:98,591,287...98,594,457
Ensembl chr11:98,592,089...98,594,455 		JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 susceptibility ISO DNA:SNP:CDS: (rs6068816) (human) RGD PMID:31264381 RGD:151665340 NCBI chr 2:170,324,877...170,339,065
Ensembl chr 2:170,324,628...170,339,065 		JBrowse link
G Dip2c disco interacting protein 2 homolog C ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr13:9,326,530...9,718,964
Ensembl chr13:9,326,564...9,718,964 		JBrowse link
G Dll4 delta like canonical Notch ligand 4 treatment ISO RGD PMID:33628824 RGD:155663482 NCBI chr 2:119,156,286...119,166,145
Ensembl chr 2:119,156,265...119,166,443 		JBrowse link
G Dnmt3b DNA methyltransferase 3B susceptibility ISO DNA:SNPs:promoter:-283T >C,-579G>T(human) RGD PMID:15528220 RGD:9589086 NCBI chr 2:153,491,332...153,529,650
Ensembl chr 2:153,491,370...153,529,650 		JBrowse link
G E2f1 E2F transcription factor 1 disease_progression
treatment		 ISO mRNA, protein:increased expression:lung RGD PMID:24755270 PMID:11313916 PMID:23792570 RGD:13464335, RGD:13464344, RGD:13464337 NCBI chr 2:154,401,320...154,411,812
Ensembl chr 2:154,401,327...154,411,812 		JBrowse link
G Eef2 eukaryotic translation elongation factor 2 ISO protein:increased expression:lung (human) RGD PMID:24589652 RGD:153297816 NCBI chr10:81,012,465...81,018,343
Ensembl chr10:81,012,465...81,018,332 		JBrowse link
G Egfr epidermal growth factor receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20837450 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158 		JBrowse link
G Elavl2 ELAV like RNA binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr 4:91,099,770...91,288,407
Ensembl chr 4:91,139,000...91,289,022 		JBrowse link
G Ep300 E1A binding protein p300 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941188 NCBI chr15:81,470,329...81,536,273
Ensembl chr15:81,469,552...81,536,278 		JBrowse link
G Epha7 Eph receptor A7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941188 NCBI chr 4:28,811,840...28,969,391
Ensembl chr 4:28,813,131...28,967,499 		JBrowse link
G Fat1 FAT atypical cadherin 1 ISO DNA:mutations:multiple (human) RGD PMID:31199602 RGD:150429733 NCBI chr 8:45,386,137...45,505,294
Ensembl chr 8:45,388,484...45,505,294 		JBrowse link
G Fgfr1 fibroblast growth factor receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941188 NCBI chr 8:26,008,808...26,067,819
Ensembl chr 8:26,003,670...26,065,734 		JBrowse link
G Foxa1 forkhead box A1 disease_progression ISO RGD PMID:22383183 RGD:151665760 NCBI chr12:57,585,750...57,594,815
Ensembl chr12:57,587,414...57,593,702 		JBrowse link
G Grik3 glutamate receptor, ionotropic, kainate 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr 4:125,384,025...125,607,966
Ensembl chr 4:125,384,493...125,607,966 		JBrowse link
G Grm8 glutamate receptor, metabotropic 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr 6:27,275,120...28,135,094
Ensembl chr 6:27,275,118...28,135,177 		JBrowse link
G Grp gastrin releasing peptide disease_progression ISO protein:increased expression:serum (human) RGD PMID:30146822 RGD:401700396 NCBI chr18:66,005,826...66,019,670
Ensembl chr18:66,005,891...66,019,667 		JBrowse link
G Id2 inhibitor of DNA binding 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23582323 NCBI chr12:25,143,798...25,146,091
Ensembl chr12:25,143,798...25,147,139 		JBrowse link
G Insm1 insulinoma-associated 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23582323 NCBI chr 2:146,064,021...146,066,940
Ensembl chr 2:146,063,841...146,066,940 		JBrowse link
G Itgb1 integrin beta 1 (fibronectin receptor beta) disease_progression
treatment		 ISO RGD PMID:21063403 PMID:12168902 RGD:13792831, RGD:13792832 NCBI chr 8:129,412,135...129,460,060
Ensembl chr 8:129,412,135...129,459,681 		JBrowse link
G Kdm6a lysine (K)-specific demethylase 6A ISO DNA:mutations:multiple: (human) RGD PMID:31199602 RGD:150429733 NCBI chr  X:18,027,101...18,147,061
Ensembl chr  X:18,028,814...18,146,175 		JBrowse link
G Khsrp KH-type splicing regulatory protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr17:57,328,049...57,338,507
Ensembl chr17:57,328,051...57,338,522 		JBrowse link
G Kif21a kinesin family member 21A ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr15:90,817,478...90,934,547
Ensembl chr15:90,817,479...90,934,151 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:15499612 NCBI chr 5:75,735,647...75,817,382
Ensembl chr 5:75,735,576...75,817,382 		JBrowse link
G Kmt2a lysine (K)-specific methyltransferase 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941188 NCBI chr 9:44,714,652...44,793,492
Ensembl chr 9:44,714,652...44,792,594 		JBrowse link
G Kmt2d lysine (K)-specific methyltransferase 2D disease_progression ISO DNA:missense mutations, insertion/deletion:plasma RGD PMID:28007623 PMID:29748005 PMID:27873319 PMID:29627316 RGD:150523766, RGD:127285383, RGD:150523768, RGD:150523767 NCBI chr15:98,729,550...98,771,958
Ensembl chr15:98,729,550...98,769,085 		JBrowse link
G Lama3 laminin, alpha 3 ISO DNA:hyper-methylation:promoter: RGD PMID:12855645 RGD:13793369 NCBI chr18:12,466,806...12,716,070
Ensembl chr18:12,466,876...12,716,070 		JBrowse link
G Lamb3 laminin, beta 3 ISO DNA:hyper-methylation:promoter: RGD PMID:12855645 RGD:13793369 NCBI chr 1:192,976,661...193,026,186
Ensembl chr 1:192,890,007...193,026,186 		JBrowse link
G Lamc2 laminin, gamma 2 ISO DNA:hyper-methylation:promoter: RGD PMID:12855645 RGD:13793369 NCBI chr 1:152,998,502...153,062,193
Ensembl chr 1:152,998,502...153,062,193 		JBrowse link
G Lyrm9 LYR motif containing 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr11:78,717,421...78,734,725
Ensembl chr11:78,717,410...78,737,696 		JBrowse link
G Max Max protein ISO DNA:loss of heterozygosity:lung RGD PMID:24362264 RGD:13793386 NCBI chr12:76,984,045...77,009,123
Ensembl chr12:76,984,043...77,008,975 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase severity ISO protein:missense mutation:cds:p.A222V (human) RGD PMID:17533396 RGD:4891158 NCBI chr 4:148,123,534...148,144,019
Ensembl chr 4:148,123,534...148,144,008 		JBrowse link
G Mtor mechanistic target of rapamycin kinase disease_progression ISO DNA:SNP: :rs2536(human) RGD PMID:28280736 RGD:13825123 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140 		JBrowse link
G Myc myelocytomatosis oncogene disease_progression IMP RGD PMID:28089889 RGD:13793389 NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223 		JBrowse link
G Mycl v-myc avian myelocytomatosis viral oncogene lung carcinoma derived ISO CTD Direct Evidence: therapeutic CTD PMID:22941189 NCBI chr 4:122,889,414...122,896,278
Ensembl chr 4:122,889,445...122,896,278 		JBrowse link
G Ndrg1 N-myc downstream regulated gene 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15341671 NCBI chr15:66,801,167...66,841,490
Ensembl chr15:66,801,167...66,841,489 		JBrowse link
G Notch1 notch 1 treatment ISO RGD PMID:33628824 RGD:155663482 NCBI chr 2:26,347,914...26,393,834
Ensembl chr 2:26,347,915...26,406,675 		JBrowse link
G Pbrm1 polybromo 1 disease_progression ISO RGD PMID:29748005 RGD:127285383 NCBI chr14:30,741,095...30,843,549
Ensembl chr14:30,741,095...30,843,549 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO ClinVar Annotator: match by term: Small cell lung carcinoma ClinVar PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More... NCBI chr 3:32,451,203...32,520,256
Ensembl chr 3:32,451,820...32,522,635 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 disease_progression ISO DNA:SNPs: :rs3756668,rs12755(human) RGD PMID:28280736 RGD:13825123 NCBI chr13:101,817,269...101,904,725
Ensembl chr13:101,817,071...101,904,725 		JBrowse link
G Plscr4 phospholipid scramblase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr 9:92,339,431...92,374,509
Ensembl chr 9:92,339,426...92,374,509 		JBrowse link
G Pten phosphatase and tensin homolog ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Small cell lung carcinoma		 CTD
ClinVar		 PMID:1945792 PMID:9467011 PMID:9915974 PMID:10866302 PMID:11051241 More... NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560 		JBrowse link
G Ptk2 PTK2 protein tyrosine kinase 2 disease_progression ISO DNA:CNV:: RGD PMID:21800286 PMID:20802517 RGD:13825133, RGD:13825141 NCBI chr15:73,076,951...73,297,192
Ensembl chr15:73,076,951...73,295,129 		JBrowse link
G Rad52 RAD52 homolog, DNA repair protein susceptibility
treatment		 ISO DNA:SNP:3'utr: (rs7963551) (human)
DNA:SNP: (rs10774474)(human)		 RGD PMID:26629180 PMID:27531263 RGD:151660337, RGD:151660339 NCBI chr 6:119,878,781...119,899,789
Ensembl chr 6:119,879,659...119,899,789 		JBrowse link
G Rarb retinoic acid receptor, beta ISO DNA:methylation: : RGD PMID:29851970 RGD:13825142 NCBI chr14:5,387,365...6,038,924
Ensembl chr14:5,650,540...6,038,924 		JBrowse link
G Rassf8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr 6:145,692,292...145,766,805
Ensembl chr 6:145,692,474...145,766,805 		JBrowse link
G Rb1 RB transcriptional corepressor 1 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Small cell lung carcinoma		 CTD
ClinVar		 PMID:1352883 PMID:2594029 PMID:7881418 PMID:9632788 PMID:9671401 More... NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262 		JBrowse link
G Rictor RPTOR independent companion of MTOR, complex 2 severity ISO associated with Neoplasm Metastasis; protein:increased expression:lung, lymph node (human)
DNA:CNV, amplification:exon (human)		 RGD PMID:31454632 PMID:27863413 RGD:152995447, RGD:152995517 NCBI chr15:6,737,827...6,829,882
Ensembl chr15:6,737,860...6,829,882 		JBrowse link
G Rims2 regulating synaptic membrane exocytosis 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr15:39,061,681...39,547,768
Ensembl chr15:39,061,656...39,547,768 		JBrowse link
G Runx1t1 RUNX1 translocation partner 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr 4:13,742,628...13,895,056
Ensembl chr 4:13,743,436...13,893,649 		JBrowse link
G Satb2 special AT-rich sequence binding protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr 1:56,833,145...57,019,350
Ensembl chr 1:56,833,140...57,017,809 		JBrowse link
G Skp2 S-phase kinase-associated protein 2 ISO mRNA:increased expression:lung: RGD PMID:12107105 RGD:13825152 NCBI chr15:9,112,070...9,155,512
Ensembl chr15:9,112,073...9,155,512 		JBrowse link
G Slit2 slit guidance ligand 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941188 NCBI chr 5:48,138,633...48,465,077
Ensembl chr 5:48,140,480...48,465,075 		JBrowse link
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26343384 NCBI chr 9:21,527,377...21,615,526
Ensembl chr 9:21,527,465...21,615,526 		JBrowse link
G Sox2 SRY (sex determining region Y)-box 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr 3:34,704,144...34,706,610
Ensembl chr 3:34,704,554...34,706,610 		JBrowse link
G Tmem132d transmembrane protein 132D ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr 5:127,860,555...128,510,141
Ensembl chr 5:127,858,694...128,510,141 		JBrowse link
G Trp53 transformation related protein 53 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Small cell lung cancer | ClinVar Annotator: match by term: Small cell lung carcinoma		 CTD
ClinVar		 PMID:1359493 PMID:1565143 PMID:1565144 PMID:1569604 PMID:1631137 More... NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
G Trp73 transformation related protein 73 ISO DNA:mutations:multiple: (human) RGD PMID:26168399 RGD:151347582 NCBI chr 4:154,140,706...154,224,332
Ensembl chr 4:154,140,706...154,224,665 		JBrowse link
G Ttr transthyretin ISO protein:increased expression:lung (human) RGD PMID:26943652 RGD:151665207 NCBI chr18:20,797,266...20,807,383
Ensembl chr18:20,798,337...20,807,378 		JBrowse link
G Ubxn11 UBX domain protein 11 ISO ClinVar Annotator: match by term: Small cell lung cancer | ClinVar Annotator: match by term: Small cell lung carcinoma ClinVar NCBI chr 4:133,829,811...133,854,095
Ensembl chr 4:133,829,881...133,854,904 		JBrowse link
G Xpo5 exportin 5 severity ISO DNA:snp, haplotype:3' utr:c.*659A>C (rs11077) (human) RGD PMID:24648983 RGD:11041738 NCBI chr17:46,513,737...46,554,524
Ensembl chr17:46,513,708...46,554,524 		JBrowse link
G Zdbf2 zinc finger, DBF-type containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr 1:63,239,517...63,353,735
Ensembl chr 1:63,312,424...63,353,735 		JBrowse link
prostate small cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brca2 breast cancer 2, early onset ISO ClinVar Annotator: match by term: Metastatic Prostate Small Cell Carcinoma ClinVar PMID:10660329 PMID:11597388 PMID:11802209 PMID:15024741 PMID:15689453 More... NCBI chr 5:150,445,759...150,493,612
Ensembl chr 5:150,446,095...150,493,794 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18301
    disease of cellular proliferation 7493
      cancer 5429
        cell type cancer 3732
          carcinoma 3199
            small cell carcinoma 105
              Bartholin's gland small cell carcinoma 0
              Desmoplastic Cerebral Astrocytoma of Infancy 0
              ampulla of Vater small cell carcinoma 0
              bladder small cell carcinoma 0
              colon small cell carcinoma 0
              endometrial small cell carcinoma 0
              esophagus small cell carcinoma 1
              gallbladder small cell carcinoma 0
              gastric small cell carcinoma 0
              laryngeal small cell carcinoma 0
              lung small cell carcinoma + 88
              prostate small cell carcinoma 1
              thymus small cell carcinoma 0
              ureter small cell carcinoma 0
paths to the root