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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:inflammatory bowel disease
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Accession:DOID:0050589 term browser browse the term
Definition:An intestinal disease characterized by inflammation located in all parts of digestive tract. (DO)
Synonyms:exact_synonym: inflammatory bowel diseases
 narrow_synonym: CROHN DISEASE-ASSOCIATED GROWTH FAILURE, SUSCEPTIBILITY TO;   VERY EARLY ONSET INFLAMMATORY BOWEL DISEASE;   regional enteritis;   ulcerative colitis
 related_synonym: Inflammatory bowel disease 1, susceptibility to
 primary_id: MESH:D015212
 xref: NCI:C3138;   OMIM:PS266600;   OMIM:PS614328
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
 
inflammatory bowel disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing ISO protein:decreased expression:serum RGD PMID:18849144 RGD:5686819 NCBI chrNW_004936578:3,168,599...3,179,369 JBrowse link
G Ager advanced glycosylation end-product specific receptor ISO RGD PMID:21939913 RGD:6767556 NCBI chrNW_004936727:1,418,342...1,422,005 JBrowse link
G Agt angiotensinogen ISO DNA:polymorphism: :p.M235T (human) RGD PMID:20717043 RGD:11039049 NCBI chrNW_004936484:19,713,299...19,721,144 JBrowse link
G Alpi alkaline phosphatase, intestinal ISO DNA:mutations:cds: RGD PMID:29567797 RGD:14367877 NCBI chrNW_004936525:4,616,212...4,619,932 JBrowse link
G Ang angiogenin ISO protein:increased expression:serum RGD PMID:20629092 RGD:6892712 NCBI chrNW_004936880:39,372...40,070 JBrowse link
G Ano6 anoctamin 6 ISO associated with Spondylitis, Ankylosing;DNA:SNP: :rs17095830(human) RGD PMID:23308121 RGD:9684849 NCBI chrNW_004936512:3,649,103...3,736,274 JBrowse link
G Apc APC regulator of WNT signaling pathway ISO CTD Direct Evidence: marker/mechanism CTD PMID:18716850 NCBI chrNW_004936531:6,899,580...7,019,016 JBrowse link
G Apc2 APC regulator of WNT signaling pathway 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18716850 NCBI chrNW_004936588:767,115...787,321 JBrowse link
G Atg16l1 autophagy related 16 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26192919 NCBI chrNW_004936525:3,973,574...4,010,442 JBrowse link
G B2m beta-2-microglobulin ISO RGD PMID:20015205 RGD:6482693 NCBI chrNW_004936471:7,646,504...7,655,656 JBrowse link
G Card9 caspase recruitment domain family member 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21983784 NCBI chrNW_004936669:1,428,208...1,438,012 JBrowse link
G Cdh2 cadherin 2 ISO RGD PMID:7502046 RGD:734737 NCBI chrNW_004936550:6,885,484...7,067,001 JBrowse link
G Crp C-reactive protein ISO RGD PMID:22483567 RGD:6482301 NCBI chrNW_004936740:885,855...888,854 JBrowse link
G Cul2 cullin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21983784 NCBI chrNW_004936574:3,310,304...3,408,389 JBrowse link
G Esr2 estrogen receptor 2 ISO RGD PMID:14500559 RGD:5509042 NCBI chrNW_004936495:7,956,168...8,018,356 JBrowse link
G Fgf23 fibroblast growth factor 23 disease_progression ISO protein:increased expression:serum: RGD PMID:22551310 RGD:10044237 NCBI chrNW_004936606:4,555,034...4,561,961 JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase ISO protein, mRNA:increased expression: colonic mucosa: inflamed tissue only RGD PMID:16195422 RGD:5688766 NCBI chrNW_004936516:5,551,192...5,578,796 JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 ISO protein:increased expression RGD PMID:21864296 RGD:5685671 NCBI chrNW_004936487:13,348,465...13,352,717 JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 ISO RGD PMID:21135124 RGD:6218980 NCBI chrNW_004936542:7,577,192...7,581,598 JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:15638228, PMID:28067908 RGD:1625756 NCBI chrNW_004936659:616,570...627,172 JBrowse link
G Ifng interferon gamma treatment ISO RGD PMID:31062617 RGD:14975125 NCBI chrNW_004936545:6,139,130...6,144,543 JBrowse link
G Igf2 insulin like growth factor 2 disease_progression ISO protein:increased expression:serum RGD PMID:12548059, PMID:20683203 RGD:5509948, RGD:5509968 NCBI chrNW_004936816:972,902...981,232 JBrowse link
G Igfbp3 insulin like growth factor binding protein 3 ISO RGD PMID:15844718 RGD:1626117 NCBI chrNW_004936478:20,511,490...20,518,251 JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta treatment ISO RGD PMID:22018461 RGD:7495770 NCBI chrNW_004936785:358,128...406,751 JBrowse link
G Il10 interleukin 10 no_association
treatment
ISO ClinVar Annotator: match by term: Inflammatory bowel disease
DNA:SNP: :rs1800896 (human)
DNA:SNP: :rs3024505 (human)
CTD Direct Evidence: marker/mechanism
RGD
ClinVar
CTD
PMID:22511846, PMID:23291587, PMID:25741868, PMID:27468578, PMID:27783946, PMID:28411859, PMID:28492532, PMID:30290665, PMID:31062617 RGD:11534627, RGD:14975125, RGD:7364854 NCBI chrNW_004936557:5,834,874...5,838,502 JBrowse link
G Il10ra interleukin 10 receptor subunit alpha ISO ClinVar Annotator: match by term: Inflammatory bowel disease ClinVar NCBI chrNW_004936542:3,099,484...3,113,159 JBrowse link
G Il10rb interleukin 10 receptor subunit beta ISO ClinVar Annotator: match by term: Inflammatory bowel disease ClinVar NCBI chrNW_004936500:9,033,077...9,057,465 JBrowse link
G Il18rap interleukin 18 receptor accessory protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:21983784 NCBI chrNW_004936713:1,087,884...1,115,512 JBrowse link
G Il19 interleukin 19 ISO ClinVar Annotator: match by term: Inflammatory bowel disease ClinVar PMID:25741868, PMID:28492532 NCBI chrNW_004936557:5,765,093...5,769,853 JBrowse link
G Il1rn interleukin 1 receptor antagonist treatment ISO RGD PMID:12184521 RGD:10450573 NCBI chrNW_004936783:1,447,158...1,466,331 JBrowse link
G Il21r interleukin 21 receptor ISO protein:increased expression:gut mucosa,leukocytes, mononuclear RGD PMID:19322899 RGD:6892935 NCBI chrNW_004936501:11,100,170...11,112,112 JBrowse link
G Il23r interleukin 23 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21983784, PMID:23291587, PMID:26192919 NCBI chrNW_004936591:4,365,598...4,425,053 JBrowse link
G Il33 interleukin 33 severity ISO RGD PMID:24491821 RGD:39938952 NCBI chrNW_004936539:763,755...791,461 JBrowse link
G Il5 interleukin 5 susceptibility ISO RGD PMID:22018693 RGD:5687148 NCBI chrNW_004936647:2,647,982...2,651,477 JBrowse link
G Inava innate immunity activator ISO CTD Direct Evidence: marker/mechanism CTD PMID:21983784 NCBI chrNW_004936567:3,443,053...3,458,184 JBrowse link
G Irgm immunity related GTPase M ISO CTD Direct Evidence: marker/mechanism CTD PMID:26192919 NCBI chrNW_004936504:4,055,091...4,056,089 JBrowse link
G Itga4 integrin subunit alpha 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28067908 NCBI chrNW_004936509:10,215,283...10,293,653 JBrowse link
G Itgal integrin subunit alpha L ISO CTD Direct Evidence: marker/mechanism CTD PMID:28067908 NCBI chrNW_004936501:12,921,509...12,966,791 JBrowse link
G Itgb8 integrin subunit beta 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28067908 NCBI chrNW_004936546:6,352,186...6,447,458 JBrowse link
G Klkb1 kallikrein B1 ISO RGD PMID:8625762 RGD:7327139 NCBI chrNW_004936554:3,227,395...3,256,710 JBrowse link
G Krt8 keratin 8 ISO ClinVar Annotator: match by term: Inflammatory bowel disease ClinVar PMID:15090596, PMID:25741868 NCBI chrNW_004936512:10,247,049...10,254,748 JBrowse link
G LOC101958024 submaxillary mucin-like protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:21983784 NCBI chrNW_004936607:418,290...443,988 JBrowse link
G LOC101967032 cytochrome b-245 light chain ISO ClinVar Annotator: match by term: Very early onset inflammatory bowel disease ClinVar PMID:3368442, PMID:9445163, PMID:10440830, PMID:19388116, PMID:25741868, PMID:30709874 NCBI chrNW_004936641:1,036,967...1,044,954 JBrowse link
G LOC101976500 haptoglobin ISO RGD PMID:16775491 RGD:5147444 NCBI chrNW_004936475:21,841,054...21,845,821 JBrowse link
G Ltf lactotransferrin ISO RGD PMID:9791051 RGD:7243943 NCBI chrNW_004936596:344,287...373,788 JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO DNA:SNP: :1298A>C (human) RGD PMID:17111197 RGD:10449410 NCBI chrNW_004936474:623,438...637,849 JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: REGIONAL ENTERITIS
ClinVar Annotator: match by term: Inflammatory bowel disease 1, susceptibility to
CTD
ClinVar
PMID:11385576, PMID:11385577, PMID:11425413, PMID:11875755, PMID:11910337, PMID:12019468, PMID:12512038, PMID:12557156, PMID:12577202, PMID:14765395, PMID:15024686, PMID:15190267, PMID:15198989, PMID:15571588, PMID:15770725, PMID:15967635, PMID:18240302, PMID:18489434, PMID:18541930, PMID:19467619, PMID:19713276, PMID:20959815, PMID:21274544, PMID:21335489, PMID:21548950, PMID:21830272, PMID:21914217, PMID:21983784, PMID:22684479, PMID:23102769, PMID:24033266, PMID:25741868, PMID:26070941, PMID:26192919, PMID:26500656, PMID:28450277, PMID:28492532 NCBI chrNW_004936475:3,708,069...3,742,845 JBrowse link
G Nos2 nitric oxide synthase 2 ISO protein:increased expression:colon (rat) RGD PMID:21958875 RGD:5508753 NCBI chrNW_004936538:4,052,277...4,097,051 JBrowse link
G Nox1 NADPH oxidase 1 ISO ClinVar Annotator: match by term: Very early onset inflammatory bowel disease ClinVar PMID:28492532, PMID:30709874 NCBI chrNW_004936584:6,023,960...6,040,041 JBrowse link
G Npsr1 neuropeptide S receptor 1 ISO RGD PMID:17854592 RGD:4891931 NCBI chrNW_004936478:10,352,894...10,542,949 JBrowse link
G Pdgfb platelet derived growth factor subunit B ISO RGD PMID:11780721 RGD:6482691 NCBI chrNW_004936492:2,353,840...2,368,573 JBrowse link
G Plcg2 phospholipase C gamma 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28067908 NCBI chrNW_004936475:29,248,533...29,377,335 JBrowse link
G Pomc proopiomelanocortin ISO protein:alternative form:large intestine epithelium: alphaMSH RGD PMID:9145424, PMID:21741932 RGD:5508804, RGD:5508805 NCBI chrNW_004936493:7,060,747...7,065,276 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11820457 NCBI chrNW_004936481:3,821,564...3,828,086 JBrowse link
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21983784 NCBI chrNW_004936690:2,180,804...2,232,869 JBrowse link
G Rassf1 Ras association domain family member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24146755 NCBI chrNW_004936529:1,857,177...1,866,198 JBrowse link
G Sfrp1 secreted frizzled related protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18716850 NCBI chrNW_004936785:1,276,478...1,320,397 JBrowse link
G Sfrp2 secreted frizzled related protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18716850 NCBI chrNW_004936576:604,174...612,440 JBrowse link
G Slamf8 SLAM family member 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28067908 NCBI chrNW_004936740:776,557...786,182 JBrowse link
G Slc11a1 solute carrier family 11 member 1 ISO DNA:polymorphisms: :1730G>A (human)
CTD Direct Evidence: marker/mechanism
DNA:point mutation:promoter:-237C>T (human)
RGD
CTD
PMID:16059695, PMID:16597321, PMID:21128323 RGD:5684929, RGD:5684952 NCBI chrNW_004936569:888,309...895,991 JBrowse link
G Slc6a14 solute carrier family 6 member 14 ISO protein:decreased expression:epithelial cell, colon RGD PMID:17065219 RGD:1625272 NCBI chrNW_004936479:13,024,831...13,051,908 JBrowse link
G Tgfb1 transforming growth factor beta 1 treatment ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:28891831, PMID:29483653 RGD:14995457 NCBI chrNW_004936661:3,742,080...3,758,266 JBrowse link
G Themis thymocyte selection associated ISO DNA:frameshift mutation: RGD PMID:22275874 RGD:38599149 NCBI chrNW_004936639:1,739,380...1,915,545 JBrowse link
G Tnf tumor necrosis factor treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:12184521, PMID:15086448, PMID:27793764 RGD:10450573 NCBI chrNW_004936727:1,936,066...1,937,766 JBrowse link
G Tnfsf15 TNF superfamily member 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26192919 NCBI chrNW_004936487:3,959,224...3,975,959 JBrowse link
G Tpmt thiopurine S-methyltransferase treatment ISO RGD PMID:17026564 RGD:11038726 NCBI chrNW_004936552:3,899,445...3,917,774 JBrowse link
G Vegfa vascular endothelial growth factor A disease_progression ISO protein:increased expression:serum,colon: RGD PMID:23642997 RGD:11079180 NCBI chrNW_004936476:16,245,134...16,261,180 JBrowse link
G Vnn1 vanin 1 ISO CTD Direct Evidence: therapeutic CTD PMID:17145956 NCBI chrNW_004936560:701,857...729,516 JBrowse link
chemical colitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace2 angiotensin I converting enzyme 2 severity ISO Ace2 inhibitor RGD PMID:19517214 RGD:40818410 NCBI chrNW_004936470:4,964,526...5,011,808 JBrowse link
G Casp3 caspase 3 treatment ISO RGD PMID:28740344 RGD:13782278 NCBI chrNW_004936554:4,571,072...4,593,765 JBrowse link
G Casp7 caspase 7 treatment ISO RGD PMID:28740344 RGD:13782278 NCBI chrNW_004936486:4,082,664...4,114,942 JBrowse link
G LOC101968921 angiotensin-converting enzyme ISO protein:increased expression:small intestine, large intestine:extracellular space (mouse) RGD PMID:26401072 RGD:11555935 NCBI chrNW_004936541:4,157,847...4,178,156 JBrowse link
Clostridium difficile colitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il23a interleukin 23 subunit alpha severity ISO RGD PMID:26455347 RGD:11097134 NCBI chrNW_004936646:743,630...745,998 JBrowse link
G Il33 interleukin 33 severity
treatment
ISO RGD PMID:32156806 RGD:40400894 NCBI chrNW_004936539:763,755...791,461 JBrowse link
colitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 ADAM metallopeptidase domain 17 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24548422 NCBI chrNW_004936532:5,864,851...5,904,005 JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO RGD PMID:17604368, PMID:21479819 RGD:5686754, RGD:5686898 NCBI chrNW_004936578:3,168,599...3,179,369 JBrowse link
G Adk adenosine kinase ISO RGD PMID:11123368 RGD:6482664 NCBI chrNW_004936521:4,560,078...5,023,780 JBrowse link
G Adrb3 adrenoceptor beta 3 ISO mRNA:decreased expression:distal colon, mucosa (rat) RGD PMID:18492028 RGD:5684890 NCBI chrNW_004936710:1,410,589...1,413,279 JBrowse link
G Ahr aryl hydrocarbon receptor ISO CTD Direct Evidence: therapeutic CTD PMID:27783946 NCBI chrNW_004936546:3,737,908...3,783,492 JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:15821759 NCBI chrNW_004936554:7,807,914...7,848,691 JBrowse link
G Anxa1 annexin A1 ISO protein:increased expression:colon, neutrophil RGD PMID:10489933 RGD:2306920 NCBI chrNW_004936503:9,124,314...9,142,372 JBrowse link
G Apln apelin ISO RGD PMID:17391779 RGD:1626177 NCBI chrNW_004936479:1,889,930...1,899,811 JBrowse link
G Apoa4 apolipoprotein A4 ISO human protein in mouse model RGD PMID:15254593 RGD:5685667 NCBI chrNW_004936542:2,098,683...2,101,127 JBrowse link
G Aqp7 aquaporin 7 ISO associated with Infection;mRNA, protein:decreased expression:colon RGD PMID:15338270 RGD:1626292 NCBI chrNW_004936524:1,898,635...1,915,078 JBrowse link
G Arrb1 arrestin beta 1 ISO protein:increased expression:colon (rat) RGD PMID:21066892 RGD:5509893 NCBI chrNW_004936498:4,089,621...4,172,749 JBrowse link
G Atp5f1d ATP synthase F1 subunit delta treatment ISO RGD PMID:23840258 RGD:13792680 NCBI chrNW_004936588:612,255...614,894 JBrowse link
G Bdnf brain derived neurotrophic factor ISO protein:increased expression:dorsal root ganglion: RGD PMID:19932037 RGD:8657331 NCBI chrNW_004936540:5,530,081...5,582,765 JBrowse link
G Bmp6 bone morphogenetic protein 6 ISO RGD PMID:22361727 RGD:7242194 NCBI chrNW_004936534:4,707,658...4,871,865 JBrowse link
G Cat catalase ISO RGD PMID:21463646 RGD:5130869 NCBI chrNW_004936533:3,601,270...3,637,128 JBrowse link
G Cckbr cholecystokinin B receptor ISO RGD PMID:15102523 RGD:2311333 NCBI chrNW_004936842:329,551...341,491 JBrowse link
G Cd36 CD36 molecule ISO RGD PMID:19117124 RGD:6893503 NCBI chrNW_004936810:791,823...838,303 JBrowse link
G Cd40 CD40 molecule ISO RGD PMID:15591506 RGD:5508169 NCBI chrNW_004936514:6,936,915...6,947,246 JBrowse link
G Chek2 checkpoint kinase 2 ISO ClinVar Annotator: match by term: Colitis ClinVar PMID:10617473, PMID:11053450, PMID:11479205, PMID:11719428, PMID:11967536, PMID:12094328, PMID:12533788, PMID:12690581, PMID:14648717, PMID:14648718, PMID:14648719, PMID:15122511, PMID:15488637, PMID:15492928, PMID:15520402, PMID:16257342, PMID:16492927, PMID:16880452, PMID:17085682, PMID:18172190, PMID:19338683, PMID:19805189, PMID:21807500, PMID:21956126, PMID:22006311, PMID:22058428, PMID:22419737, PMID:22811390, PMID:22994785, PMID:23469205, PMID:24033266, PMID:24884479, PMID:25431674, PMID:25741868, PMID:26084796, PMID:26467025, PMID:26641009, PMID:26681312, PMID:26822237, PMID:26845104, PMID:26884562, PMID:27083775, PMID:27153395, PMID:27269948, PMID:27433846, PMID:27751358, PMID:27798748, PMID:28125075, PMID:28135145, PMID:28195393, PMID:28492532, PMID:28503720, PMID:28514723, PMID:28727877, PMID:28734145, PMID:28779002, PMID:28802053, PMID:28874143, PMID:29351919, PMID:29489754, PMID:30311386 NCBI chrNW_004936657:2,805,947...2,848,180 JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex treatment ISO RGD PMID:17543437 RGD:2298659 NCBI chrNW_004936636:33,933...78,990 JBrowse link
G Ciita class II major histocompatibility complex transactivator severity ISO protein:increased expression:T cells:constitutive expression of transgene increases severity
ClinVar Annotator: match by term: Colitis
RGD
ClinVar
PMID:17043423, PMID:25741868, PMID:28492532 RGD:5491188 NCBI chrNW_004936530:9,033,510...9,073,341 JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 ISO mRNA, protein:decreased expression:intestine, myenteric nerve plexus RGD PMID:17586086, PMID:21330446 RGD:5131259, RGD:5490987 NCBI chrNW_004936478:6,901,098...6,947,719 JBrowse link
G Ctsl cathepsin L ISO protein:increased activity:cecum, colon, spinal cord RGD PMID:21802389 RGD:5686873 NCBI chrNW_004936680:3,047,355...3,050,640 JBrowse link
G Ctss cathepsin S ISO protein:increased activity:cecum, colon, spinal cord RGD PMID:21802389 RGD:5686873 NCBI chrNW_004936580:963,176...991,732 JBrowse link
G Cxcl8 C-X-C motif chemokine ligand 8 ISO associated with Helicobacter Infections;mRNA:decreased expression:colon (mouse, Helicobacter hepaticus) RGD PMID:17242461 RGD:38549339 NCBI chrNW_004936598:1,779,471...1,781,353 JBrowse link
G Dusp1 dual specificity phosphatase 1 severity ISO RGD PMID:22461024 RGD:7771532 NCBI chrNW_004936609:2,688,170...2,691,057 JBrowse link
G Esr2 estrogen receptor 2 ISO mRNA:decreased expression:colon RGD PMID:21252046 RGD:5508810 NCBI chrNW_004936495:7,956,168...8,018,356 JBrowse link
G Fgf19 fibroblast growth factor 19 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27580383 NCBI chrNW_004936599:923,943...932,428 JBrowse link
G Flna filamin A ISO ClinVar Annotator: match by term: Colitis ClinVar PMID:25741868, PMID:28492532 NCBI chrNW_004936809:1,097,288...1,123,206 JBrowse link
G Gcg glucagon ISO CTD Direct Evidence: therapeutic CTD PMID:22323126 NCBI chrNW_004936469:16,906,658...16,916,045 JBrowse link
G Ghrl ghrelin and obestatin prepropeptide ISO CTD Direct Evidence: therapeutic CTD PMID:19617644 NCBI chrNW_004936602:3,037,862...3,044,863 JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 ISO mRNA:increased expression:kidney: RGD PMID:23307618 RGD:7245473 NCBI chrNW_004936515:6,030,402...6,051,161 JBrowse link
G Hmox1 heme oxygenase 1 treatment ISO CTD Direct Evidence: therapeutic
protein:increased expression:colon:
CTD
RGD
PMID:16365149, PMID:21444764, PMID:21853095, PMID:22261574 RGD:10766442, RGD:7207796 NCBI chrNW_004936492:5,042,353...5,049,216 JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO protein:increased expression:colon: RGD PMID:22261574 RGD:7207796 NCBI chrNW_004936659:616,570...627,172 JBrowse link
G Icos inducible T cell costimulator ISO protein:increased expression:T-cell RGD PMID:14731127 RGD:1624274 NCBI chrNW_004936631:562,650...572,263 JBrowse link
G Ifng interferon gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:24548422 NCBI chrNW_004936545:6,139,130...6,144,543 JBrowse link
G Igf1 insulin like growth factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24782617 NCBI chrNW_004936492:11,709,623...11,784,028 JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta treatment ISO RGD PMID:17543437 RGD:2298659 NCBI chrNW_004936785:358,128...406,751 JBrowse link
G Il10 interleukin 10 treatment ISO CTD Direct Evidence: marker/mechanism|therapeutic RGD
CTD
PMID:19238344, PMID:21807089, PMID:21949848, PMID:22119709, PMID:22461024, PMID:23771723, PMID:24314293 RGD:7349385, RGD:7365024, RGD:7771532 NCBI chrNW_004936557:5,834,874...5,838,502 JBrowse link
G Il17a interleukin 17A ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:colon
RGD
CTD
PMID:14962796, PMID:20881082, PMID:24548422 RGD:4781448, RGD:4888509 NCBI chrNW_004936476:8,621,860...8,625,008 JBrowse link
G Il1b interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:22969190, PMID:23810507, PMID:24548422 RGD:7204699 NCBI chrNW_004936783:1,251,678...1,256,807 JBrowse link
G Il1rl1 interleukin 1 receptor like 1 severity ISO RGD PMID:23172891 RGD:40400694 NCBI chrNW_004936713:1,020,969...1,035,012 JBrowse link
G Il33 interleukin 33 severity ISO RGD PMID:23172891, PMID:28423665 RGD:39939041, RGD:40400694 NCBI chrNW_004936539:763,755...791,461 JBrowse link
G Il4 interleukin 4 treatment ISO CTD Direct Evidence: therapeutic RGD
CTD
PMID:9389741, PMID:24314293 RGD:8142400 NCBI chrNW_004936647:2,510,457...2,518,576 JBrowse link
G Il5 interleukin 5 ISO protein: increased expression RGD PMID:22018693 RGD:5687148 NCBI chrNW_004936647:2,647,982...2,651,477 JBrowse link
G Itgb2 integrin subunit beta 2 ISO associated with Spirochaetales infections RGD PMID:11031123 RGD:6482227 NCBI chrNW_004936778:1,286,475...1,311,184 JBrowse link
G Kdr kinase insert domain receptor ISO protein:increased expression:colon: RGD PMID:22261574 RGD:7207796 NCBI chrNW_004936482:17,537,697...17,581,320 JBrowse link
G Lct lactase ISO protein:decreased expression, increased expression:jejunum RGD PMID:17218984 RGD:1600240 NCBI chrNW_004936469:40,064,822...40,108,423 JBrowse link
G LOC101964209 C-C chemokine receptor type 1 ISO RGD PMID:16399111 RGD:2307162 NCBI chrNW_004936596:177,774...183,186 JBrowse link
G LOC101969148 cytochrome P450 1A1 ISO mRNA:increased expression:large intestine epithelium RGD PMID:21374063 RGD:5147670 NCBI chrNW_004936471:33,682,730...33,688,332 JBrowse link
G LOC101976500 haptoglobin treatment ISO RGD PMID:22457771 RGD:11041866 NCBI chrNW_004936475:21,841,054...21,845,821 JBrowse link
G Lrrk2 leucine rich repeat kinase 2 ISO RGD PMID:21983832 RGD:5508401 NCBI chrNW_004936607:628,469...761,117 JBrowse link
G Madcam1 mucosal vascular addressin cell adhesion molecule 1 ISO CTD Direct Evidence: therapeutic CTD PMID:16917232 NCBI chrNW_004936588:145,696...149,158 JBrowse link
G Mc1r melanocortin 1 receptor ISO RGD PMID:16543288 RGD:5687320 NCBI chrNW_004936641:193,885...198,730 JBrowse link
G Mif macrophage migration inhibitory factor ISO CTD Direct Evidence: therapeutic RGD
CTD
PMID:12105854, PMID:17324399 RGD:1641979 NCBI chrNW_004936619:1,207,058...1,208,010 JBrowse link
G Mpo myeloperoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23810507 NCBI chrNW_004936490:4,809,773...4,819,070 JBrowse link
G Msh2 mutS homolog 2 ISO RGD PMID:23883737 RGD:10412318 NCBI chrNW_004936508:4,943,987...5,013,356 JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming treatment ISO protein:decreased sulfation:descending colon
mRNA:decreased expression:colon
RGD PMID:12395902, PMID:19220658, PMID:21949848, PMID:23395625 RGD:2324675, RGD:7349356, RGD:7349360, RGD:7349385 NCBI chrNW_004936816:60,499...91,628 JBrowse link
G Nampt nicotinamide phosphoribosyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23810507 NCBI chrNW_004936479:17,682,070...17,716,713 JBrowse link
G Nod1 nucleotide binding oligomerization domain containing 1 ISO RGD PMID:20921147 RGD:5508755 NCBI chrNW_004936478:6,717,354...6,768,293 JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 ISO mRNA:increased expression:colon RGD PMID:16891783, PMID:20921147, PMID:21471573 RGD:1600781, RGD:5508727, RGD:5508755 NCBI chrNW_004936475:3,708,069...3,742,845 JBrowse link
G Nos2 nitric oxide synthase 2 ISO mRNA:increased expression:colon (mouse)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:8698225, PMID:16866779, PMID:17449036, PMID:21930116 RGD:4891411, RGD:5509045 NCBI chrNW_004936538:4,052,277...4,097,051 JBrowse link
G Nos3 nitric oxide synthase 3 ISO mRNA:increased expression:colon RGD PMID:17947450 RGD:2292124 NCBI chrNW_004936527:6,427,147...6,445,770 JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 ISO mRNA, protein:increased expression:neuron RGD PMID:20638179 RGD:5684542 NCBI chrNW_004936580:6,002,168...6,021,690 JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 ISO mRNA, protein:increased expression:dorsal root ganglion RGD PMID:20638179 RGD:5684542 NCBI chrNW_004936680:267,850...621,467 JBrowse link
G Pgf placental growth factor ISO RGD PMID:20142801 RGD:6483587 NCBI chrNW_004936488:4,098,187...4,111,108 JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO RGD PMID:21244371 RGD:6482682 NCBI chrNW_004936479:17,084,006...17,112,264 JBrowse link
G Pla2g2a phospholipase A2 group IIA ISO RGD PMID:17982090 RGD:6482729 NCBI chrNW_004936474:6,091,978...6,095,961 JBrowse link
G Ppara peroxisome proliferator activated receptor alpha susceptibility ISO RGD PMID:20650341 RGD:5509936 NCBI chrNW_004936629:3,672,445...3,725,645 JBrowse link
G Ppargc1a PPARG coactivator 1 alpha ISO RGD PMID:22126533 RGD:6484264 NCBI chrNW_004936477:4,881,230...5,488,208 JBrowse link
G Ptger4 prostaglandin E receptor 4 ISO RGD PMID:20833794 RGD:6483551 NCBI chrNW_004936518:1,903,636...1,916,746 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:11820457, PMID:17543437 RGD:2298659 NCBI chrNW_004936481:3,821,564...3,828,086 JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit ISO protein:increased expression:nucleus
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:18623154, PMID:23810507 RGD:2298776 NCBI chrNW_004936599:3,800,142...3,810,583 JBrowse link
G Retn resistin treatment ISO RGD PMID:22630819 RGD:7207222 NCBI chrNW_004936588:4,705,295...4,706,653 JBrowse link
G Sell selectin L ISO RGD PMID:18054560 RGD:5685703 NCBI chrNW_004936481:17,022,421...17,032,105 JBrowse link
G Selp selectin P ISO protein:increased expression:colon RGD PMID:19147805 RGD:2312310 NCBI chrNW_004936481:17,076,660...17,112,501 JBrowse link
G Selplg selectin P ligand ISO RGD PMID:22009715 RGD:6218987 NCBI chrNW_004936769:531,224...540,429 JBrowse link
G Si sucrase-isomaltase ISO mRNA, protein:decreased expression:ileum RGD PMID:16964428 RGD:1625545 NCBI chrNW_004936707:1,153,538...1,228,220 JBrowse link
G Sirt1 sirtuin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19940103, PMID:24548422, PMID:24782617 NCBI chrNW_004936521:10,296,097...10,316,673 JBrowse link
G Slc11a1 solute carrier family 11 member 1 ISO RGD PMID:19016783 RGD:5684975 NCBI chrNW_004936569:888,309...895,991 JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17551092 NCBI chrNW_004936561:3,826,802...3,844,406 JBrowse link
G Tac1 tachykinin precursor 1 ISO RGD PMID:18715640 RGD:2304260 NCBI chrNW_004936585:2,932,783...2,941,141 JBrowse link
G Tacr1 tachykinin receptor 1 ISO RGD PMID:18715640 RGD:2304260 NCBI chrNW_004936556:1,266,621...1,421,271 JBrowse link
G Tacr2 tachykinin receptor 2 ISO RGD PMID:12490601, PMID:18715640 RGD:2304260, RGD:5147478 NCBI chrNW_004936521:9,053,179...9,065,790 JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24548422 NCBI chrNW_004936492:6,996,627...7,046,137 JBrowse link
G Tlr3 toll like receptor 3 ISO mRNA:increased expression:large intestine mucosa (rat) RGD PMID:20011045 RGD:5128708 NCBI chrNW_004936554:3,370,766...3,388,125 JBrowse link
G Tlr4 toll like receptor 4 ISO protein:increased expression:colon RGD PMID:19002562, PMID:19924809 RGD:2312573, RGD:7794773 NCBI chrNW_004936487:6,519,140...6,532,018 JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:23810507, PMID:24548422 NCBI chrNW_004936727:1,936,066...1,937,766 JBrowse link
G Tst thiosulfate sulfurtransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19647029 NCBI chrNW_004936492:3,880,545...3,886,881 JBrowse link
G Ucn urocortin ISO mRNA:altered expression:distal colon (rat) RGD PMID:21330446 RGD:5490987 NCBI chrNW_004936493:5,258,574...5,260,692 JBrowse link
G Ucn2 urocortin 2 ISO mRNA:increased expression:colon (rat) RGD PMID:17586086 RGD:5131259 NCBI chrNW_004936529:347,411...348,040 JBrowse link
G Vcam1 vascular cell adhesion molecule 1 ISO protein:increased expression:colon: RGD PMID:22261574 RGD:7207796 NCBI chrNW_004936748:785,491...802,791 JBrowse link
G Vip vasoactive intestinal peptide ISO associated with Gram-Negative Bacterial Infections RGD PMID:19661153 RGD:5685605 NCBI chrNW_004936489:5,425,778...5,434,483 JBrowse link
G Vipr2 vasoactive intestinal peptide receptor 2 ISO RGD PMID:21295288 RGD:5685384 NCBI chrNW_004936856:859,009...866,239 JBrowse link
Crohn's disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1 ATP binding cassette subfamily B member 1 susceptibility ISO RGD PMID:15505619 RGD:1598568 NCBI chrNW_004936763:1,225,355...1,308,257 JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:serum
CTD
RGD
PMID:16432373, PMID:21829567 RGD:5686726 NCBI chrNW_004936578:3,168,599...3,179,369 JBrowse link
G Agt angiotensinogen ISO ClinVar Annotator: match by term: Crohn disease, association with ClinVar PMID:9120024, PMID:9894356, PMID:13937884, PMID:15077204, PMID:17047091, PMID:20978123 NCBI chrNW_004936484:19,713,299...19,721,144 JBrowse link
G Alpi alkaline phosphatase, intestinal ISO protein:decreased expression:colonic mucosa RGD PMID:22783049 RGD:14367879 NCBI chrNW_004936525:4,616,212...4,619,932 JBrowse link
G Apln apelin ISO protein:increased expression:intestine RGD PMID:17391779 RGD:1626177 NCBI chrNW_004936479:1,889,930...1,899,811 JBrowse link
G Apoa4 apolipoprotein A4 severity ISO protein:decreased expression:blood plasma (human) RGD PMID:17206692 RGD:5685660 NCBI chrNW_004936542:2,098,683...2,101,127 JBrowse link
G Aqp7 aquaporin 7 severity ISO mRNA, protein:decreased expression:colon RGD PMID:15338270 RGD:1626292 NCBI chrNW_004936524:1,898,635...1,915,078 JBrowse link
G Atg16l1 autophagy related 16 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17435756, PMID:18438406 NCBI chrNW_004936525:3,973,574...4,010,442 JBrowse link
G Bach2 BTB domain and CNC homolog 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21102463 NCBI chrNW_004936510:2,041,004...2,375,215 JBrowse link
G Bglap bone gamma-carboxyglutamate protein ISO mRNA:decreased expression:bone
protein:undercarboxylated:serum
RGD PMID:21482072, PMID:22535626 RGD:6483321, RGD:6483546 NCBI chrNW_004936580:5,480,023...5,482,288 JBrowse link
G Bpi bactericidal permeability increasing protein ISO RGD PMID:15758620 RGD:1580079 NCBI chrNW_004936561:3,043,520...3,069,680 JBrowse link
G Ccny cyclin Y ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438405 NCBI chrNW_004936574:3,638,054...3,849,154 JBrowse link
G Cd40 CD40 molecule susceptibility ISO protein:increased expression:intestine, epithelial cell
DNA:SNP:5' utr:c.-1C>T (rs1883832) (human)
RGD PMID:20133813, PMID:20634952 RGD:5490590, RGD:5490971 NCBI chrNW_004936514:6,936,915...6,947,246 JBrowse link
G Cibar2 CBY1 interacting BAR domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17435756 NCBI chrNW_004936641:3,099,616...3,109,969 JBrowse link
G Cldn1 claudin 1 ISO RGD PMID:21748286 RGD:11341809 NCBI chrNW_004936578:98,489...113,125 JBrowse link
G Crp C-reactive protein severity ISO protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:11339241, PMID:22421709 RGD:6482309 NCBI chrNW_004936740:885,855...888,854 JBrowse link
G Dennd1b DENN domain containing 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:21102463 NCBI chrNW_004936567:6,131,433...6,353,003 JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:21102463 NCBI chrNW_004936493:6,963,406...7,013,256 JBrowse link
G Erap2 endoplasmic reticulum aminopeptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21102463 NCBI chrNW_004936523:6,545,281...6,584,403 JBrowse link
G Esr2 estrogen receptor 2 disease_progression ISO mRNA:decreased expression:colon RGD PMID:21252046 RGD:5508810 NCBI chrNW_004936495:7,956,168...8,018,356 JBrowse link
G F13a1 coagulation factor XIII A chain ISO associated with Fistula;protein:decreased activity:plasma: RGD PMID:7611208 RGD:10450739 NCBI chrNW_004936534:6,199,066...6,360,374 JBrowse link
G F2 coagulation factor II, thrombin ISO RGD PMID:21593018 RGD:5147754 NCBI chrNW_004936562:2,371,725...2,388,617 JBrowse link
G Fcgr3a Fc fragment of IgG receptor IIIa treatment ISO DNA:SNP:exon:p.F158V (rs396991) (human) RGD PMID:14987319 RGD:1304543 NCBI chrNW_004937131:42,523...49,533 JBrowse link
G Fga fibrinogen alpha chain ISO RGD PMID:19683480 RGD:5688758 NCBI chrNW_004936576:1,322,406...1,329,743 JBrowse link
G Fn1 fibronectin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19751734 NCBI chrNW_004936586:1,708,803...1,773,372 JBrowse link
G Gc GC vitamin D binding protein susceptibility ISO DNA:polymorphism:cds:p.T420K(human) RGD PMID:21832969 RGD:5509866 NCBI chrNW_004936598:3,220,029...3,256,091 JBrowse link
G Gpbar1 G protein-coupled bile acid receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23566200 NCBI chrNW_004936569:792,393...794,764 JBrowse link
G Gpx1 glutathione peroxidase 1 ISO protein:decreased expression:erythrocyte RGD PMID:20186929 RGD:11352754 NCBI chrNW_004936529:997,943...999,123 JBrowse link
G Hfe homeostatic iron regulator treatment ISO DNA:SNP: :rs2071303 (human) RGD PMID:27115882 RGD:14701051 NCBI chrNW_004936671:1,940,079...1,947,574 JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like ISO ClinVar Annotator: match by term: Inflammatory bowel disease 1 ClinVar PMID:28126021 NCBI chrNW_004936727:1,735,880...1,745,231 JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO RGD PMID:15638228 RGD:1625756 NCBI chrNW_004936659:616,570...627,172 JBrowse link
G Ifng interferon gamma ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:21829567, PMID:28070144 RGD:14974261 NCBI chrNW_004936545:6,139,130...6,144,543 JBrowse link
G Igf1 insulin like growth factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19751734 NCBI chrNW_004936492:11,709,623...11,784,028 JBrowse link
G Il10 interleukin 10 treatment ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:11113068, PMID:21102463, PMID:29899181 RGD:11049181, RGD:14975133 NCBI chrNW_004936557:5,834,874...5,838,502 JBrowse link
G Il12b interleukin 12B ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438406 NCBI chrNW_004936515:4,056,214...4,066,121 JBrowse link
G Il21r interleukin 21 receptor ISO DNA:altered methylation: : RGD PMID:22021194 RGD:6482789 NCBI chrNW_004936501:11,100,170...11,112,112 JBrowse link
G Il23r interleukin 23 receptor susceptibility ISO DNA:SNPs:multiple:
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:17068223, PMID:17435756, PMID:18438406 RGD:8549568 NCBI chrNW_004936591:4,365,598...4,425,053 JBrowse link
G Il2ra interleukin 2 receptor subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:21102463 NCBI chrNW_004936484:8,514,333...8,555,392 JBrowse link
G Irgm immunity related GTPase M ISO CTD Direct Evidence: marker/mechanism CTD PMID:17554261, PMID:18438406, PMID:19165925, PMID:21278745 NCBI chrNW_004936504:4,055,091...4,056,089 JBrowse link
G Jak2 Janus kinase 2 ISO DNA:SNP: :rs10758669 (human) RGD PMID:22269120 RGD:6483020 NCBI chrNW_004936503:111,722...243,627 JBrowse link
G Kdr kinase insert domain receptor ISO protein:increased expression:colon RGD PMID:19013462 RGD:5684406 NCBI chrNW_004936482:17,537,697...17,581,320 JBrowse link
G Lep leptin ISO CTD Direct Evidence: marker/mechanism CTD PMID:21829567 NCBI chrNW_004936479:15,394,966...15,411,334 JBrowse link
G LOC101958908 HLA class II histocompatibility antigen, DP alpha 1 chain ISO RGD PMID:12073072 RGD:6480648 NCBI chrNW_004936476:25,743,512...25,750,809 JBrowse link
G Lrrk2 leucine rich repeat kinase 2 ISO DNA:point mutation: :p.T2397M (rs3761863) (human) RGD PMID:21983832 RGD:5508401 NCBI chrNW_004936607:628,469...761,117 JBrowse link
G Madcam1 mucosal vascular addressin cell adhesion molecule 1 ISO RGD PMID:11703369 RGD:2311550 NCBI chrNW_004936588:145,696...149,158 JBrowse link
G Mki67 marker of proliferation Ki-67 ISO RGD PMID:21364546 RGD:6483536 NCBI chrNW_004936486:15,561,327...15,587,109 JBrowse link
G Mst1 macrophage stimulating 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438406 NCBI chrNW_004936529:1,298,853...1,306,088 JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28002332 NCBI chrNW_004936474:623,438...637,849 JBrowse link
G Ncf4 neutrophil cytosolic factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17435756 NCBI chrNW_004936492:4,001,711...4,015,253 JBrowse link
G Nkx2-3 NK2 homeobox 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17554261, PMID:18438405, PMID:18438406 NCBI chrNW_004936636:529,669...532,237 JBrowse link
G Nlrp3 NLR family pyrin domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19098911 NCBI chrNW_004936864:709,693...732,119 JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 no_association
susceptibility
ISO DNA:missense mutations, frameshift mutation: :p.R702W, p.G908R, 3020_3021insC (human)
DNA:frameshift mutation, missense mutations
OMIM
RGD
PMID:11385576, PMID:21155887 RGD:1600778, RGD:5508730 NCBI chrNW_004936475:3,708,069...3,742,845 JBrowse link
G Nr1h4 nuclear receptor subfamily 1 group H member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21829567 NCBI chrNW_004936492:13,315,265...13,365,186 JBrowse link
G Ocln occludin ISO RGD PMID:21748286 RGD:11341809 NCBI chrNW_004936480:99,516...152,834 JBrowse link
G Pgf placental growth factor ISO protein:increased expression:serum RGD PMID:17980128 RGD:6483592 NCBI chrNW_004936488:4,098,187...4,111,108 JBrowse link
G Phox2b paired like homeobox 2B ISO CTD Direct Evidence: marker/mechanism CTD PMID:17435756 NCBI chrNW_004936482:8,972,433...8,975,284 JBrowse link
G Plaur plasminogen activator, urokinase receptor ISO RGD PMID:21114432 RGD:6483800 NCBI chrNW_004936706:840,968...855,552 JBrowse link
G Pon1 paraoxonase 1 ISO mRNA:decreased expression:terminal ileum RGD PMID:17664137 RGD:5509924 NCBI chrNW_004936585:4,954,871...4,979,560 JBrowse link
G Pon3 paraoxonase 3 ISO mRNA:decreased expression:terminal ileum RGD PMID:17664137 RGD:5509924 NCBI chrNW_004936585:4,902,430...4,928,377 JBrowse link
G Ppara peroxisome proliferator activated receptor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:21829567 NCBI chrNW_004936629:3,672,445...3,725,645 JBrowse link
G Pparg peroxisome proliferator activated receptor gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:21829567 NCBI chrNW_004936602:1,230,907...1,368,588 JBrowse link
G Prf1 perforin 1 ISO DNA:hypermethylation RGD PMID:22021194 RGD:6482789 NCBI chrNW_004936521:8,057,874...8,060,695 JBrowse link
G Prkcq protein kinase C theta ISO ClinVar Annotator: match by term: Inflammatory bowel disease 1 ClinVar NCBI chrNW_004936484:8,048,239...8,166,058 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO protein:increased expression:colon RGD PMID:21763290 RGD:5508200 NCBI chrNW_004936481:3,821,564...3,828,086 JBrowse link
G Ptpn2 protein tyrosine phosphatase non-receptor type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17554261 NCBI chrNW_004936626:2,390,004...2,472,039 JBrowse link
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 ISO DNA:SNP:cds:rs2476601 (human) RGD PMID:18587394 RGD:6484668 NCBI chrNW_004936690:2,180,804...2,232,869 JBrowse link
G Sell selectin L ISO DNA:polymorphism: :p.F206L (human) RGD PMID:19212205 RGD:13464267 NCBI chrNW_004936481:17,022,421...17,032,105 JBrowse link
G Slc11a1 solute carrier family 11 member 1 no_association ISO DNA:polymorphisms:promoter (human)
DNA:insertion/deletion:3' utr (human)
DNA:polymorphism:promoter (human)
DNA:polymorphism: :823C>T (human)
DNA:point mutation:promoter:-237C>T (human)
CTD Direct Evidence: marker/mechanism
DNA:repeat, polymorphisms:promoter, intron:p.D543N (human)
RGD
CTD
PMID:11929588, PMID:15757519, PMID:16059695, PMID:17131479, PMID:17385031, PMID:18340647, PMID:18454481 RGD:5684938, RGD:5684939, RGD:5684941, RGD:5684942, RGD:5684952, RGD:5684956, RGD:5684968 NCBI chrNW_004936569:888,309...895,991 JBrowse link
G Slc22a5 solute carrier family 22 member 5 susceptibility ISO DNA:snp, haplotype:promoter:g.-207G>C (human) RGD PMID:15107849 RGD:1580609 NCBI chrNW_004936647:2,774,063...2,798,585 JBrowse link
G Smad3 SMAD family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21102463 NCBI chrNW_004936471:27,080,662...27,185,861 JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO DNA:SNPs: :rs744166, rs3816769 (human)
DNA:SNP: :rs744166 (human)
RGD PMID:20109474, PMID:22269120 RGD:6483020, RGD:6483027 NCBI chrNW_004936490:17,119,189...17,178,402 JBrowse link
G Tagap T cell activation RhoGTPase activating protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:21102463 NCBI chrNW_004936489:10,615,324...10,623,720 JBrowse link
G Tcf7 transcription factor 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24994854 NCBI chrNW_004936647:1,096,726...1,125,753 JBrowse link
G Thbd thrombomodulin ISO protein:decreased expression:colon, blood vessel RGD PMID:17557119 RGD:5685011 NCBI chrNW_004936620:2,563,900...2,568,117 JBrowse link
G Tlr4 toll like receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17914947 NCBI chrNW_004936487:6,519,140...6,532,018 JBrowse link
G Tnf tumor necrosis factor treatment ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:intestine mucosa
CTD
RGD
PMID:10700533, PMID:21359923, PMID:21829567, PMID:22531889 RGD:5130893, RGD:8661753 NCBI chrNW_004936727:1,936,066...1,937,766 JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A treatment ISO protein:increased expression:large intestine mucosa (rat) RGD PMID:21359923, PMID:22531889 RGD:5130893, RGD:8661753 NCBI chrNW_004936709:1,407,327...1,421,448 JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B ISO protein:increased expression:large intestine mucosa (rat) RGD PMID:21359923 RGD:5130893 NCBI chrNW_004936474:908,414...935,765 JBrowse link
G Tyk2 tyrosine kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21102463 NCBI chrNW_004936659:681,463...704,484 JBrowse link
G Vegfa vascular endothelial growth factor A ISO protein:increased expression:colon, plasma RGD PMID:19013462 RGD:5684406 NCBI chrNW_004936476:16,245,134...16,261,180 JBrowse link
G Vipr1 vasoactive intestinal peptide receptor 1 ISO RGD PMID:17611633 RGD:5685618 NCBI chrNW_004936695:2,564,917...2,597,009 JBrowse link
G Vtn vitronectin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19751734 NCBI chrNW_004936538:4,522,275...4,525,245 JBrowse link
Experimental Colitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acer3 alkaline ceramidase 3 severity ISO mRNA,protein:decreased expression, decreased activity:colon: RGD PMID:26938296 RGD:35673322 NCBI chrNW_004936498:5,496,991...5,653,206 JBrowse link
G Adam17 ADAM metallopeptidase domain 17 treatment ISO RGD PMID:11884025 RGD:632022 NCBI chrNW_004936532:5,864,851...5,904,005 JBrowse link
G Adrb3 adrenoceptor beta 3 no_association ISO mRNA:unaltered expression:colon (rat) RGD PMID:11803250 RGD:5684894 NCBI chrNW_004936710:1,410,589...1,413,279 JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha treatment ISO RGD PMID:25689466 RGD:13703055 NCBI chrNW_004936517:743,036...752,836 JBrowse link
G Csf3 colony stimulating factor 3 treatment ISO RGD PMID:16689657 RGD:11039462 NCBI chrNW_004936490:15,142,526...15,146,375 JBrowse link
G Cxcl8 C-X-C motif chemokine ligand 8 treatment ISO RGD PMID:29655167 RGD:39939058 NCBI chrNW_004936598:1,779,471...1,781,353 JBrowse link
G Ereg epiregulin ISO protein:increased expression:colonic mucosa (mouse) RGD PMID:20498653 RGD:39457688 NCBI chrNW_004936598:1,328,803...1,336,141 JBrowse link
G Fas Fas cell surface death receptor treatment ISO RGD PMID:22368862 RGD:10054108 NCBI chrNW_004936735:209,369...234,582 JBrowse link
G Foxp3 forkhead box P3 treatment ISO mRNA:increased expression:mucosa:
protein:increased expression:colon:
RGD PMID:17229795, PMID:26925602, PMID:27498708, PMID:28733028 RGD:14975101, RGD:38455994, RGD:38455995, RGD:38549362 NCBI chrNW_004936721:1,118,376...1,125,282 JBrowse link
G Hamp hepcidin antimicrobial peptide ISO protein:increased expression:colon RGD PMID:24764672 RGD:11041628 NCBI chrNW_004936570:1,009,344...1,010,654 JBrowse link
G Hsf1 heat shock transcription factor 1 ISO protein:increased acetylation:colon (rat) RGD PMID:25608526 RGD:10402402 NCBI chrNW_004936470:7,927,734...7,950,805 JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment ISO RGD PMID:10092309 RGD:11522714 NCBI chrNW_004936659:616,570...627,172 JBrowse link
G Ifng interferon gamma ISO protein:increased expression:plasma: RGD PMID:15030379, PMID:27498708 RGD:10755756, RGD:14975101 NCBI chrNW_004936545:6,139,130...6,144,543 JBrowse link
G Il10 interleukin 10 treatment ISO associated with Helicobacter Infections RGD PMID:16982822, PMID:25727887, PMID:27815529 RGD:11049170, RGD:11049485, RGD:14975260 NCBI chrNW_004936557:5,834,874...5,838,502 JBrowse link
G Il1b interleukin 1 beta treatment ISO RGD PMID:31175857 RGD:14975282 NCBI chrNW_004936783:1,251,678...1,256,807 JBrowse link
G Il1rn interleukin 1 receptor antagonist treatment ISO human protein in a rat model RGD PMID:8978354 RGD:8551835 NCBI chrNW_004936783:1,447,158...1,466,331 JBrowse link
G Il2 interleukin 2 ISO RGD PMID:16630696 RGD:8662978 NCBI chrNW_004936662:1,594,953...1,599,625 JBrowse link
G Il23a interleukin 23 subunit alpha severity ISO mRNA:increased expression:colon (mouse) RGD PMID:24028683 RGD:39458035 NCBI chrNW_004936646:743,630...745,998 JBrowse link
G Il33 interleukin 33 severity
treatment
ISO RGD PMID:25112700, PMID:28423665 RGD:39938951, RGD:39939041 NCBI chrNW_004936539:763,755...791,461 JBrowse link
G Itga2 integrin subunit alpha 2 treatment ISO RGD PMID:16534417 RGD:11530069 NCBI chrNW_004936480:14,320,292...14,417,828 JBrowse link
G Itga4 integrin subunit alpha 4 ISO protein:increased expression:colon (rat) RGD PMID:12183646 RGD:729408 NCBI chrNW_004936509:10,215,283...10,293,653 JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 ISO mRNA, protein:increased expression:colon RGD PMID:23986198 RGD:10412026 NCBI chrNW_004936521:2,000,113...2,706,010 JBrowse link
G Kdr kinase insert domain receptor ISO protein:increased expression:colon RGD PMID:19013462 RGD:5684406 NCBI chrNW_004936482:17,537,697...17,581,320 JBrowse link
G Kl klotho ISO mRNA:decreased expression:kidney: RGD PMID:20004202 RGD:10403055 NCBI chrNW_004936472:27,604,681...27,649,613 JBrowse link
G LOC101968921 angiotensin-converting enzyme treatment ISO RGD PMID:17342403, PMID:24239644 RGD:40400720, RGD:40400748 NCBI chrNW_004936541:4,157,847...4,178,156 JBrowse link
G Mapk1 mitogen-activated protein kinase 1 treatment ISO RGD PMID:27028006 RGD:13800882 NCBI chrNW_004936619:1,889,841...1,932,646 JBrowse link
G Mapk3 mitogen-activated protein kinase 3 treatment ISO RGD PMID:29037916 RGD:13800567 NCBI chrNW_004936501:12,342,670...12,390,650 JBrowse link
G Mif macrophage migration inhibitory factor severity ISO RGD PMID:15807847 RGD:36947390 NCBI chrNW_004936619:1,207,058...1,208,010 JBrowse link
G Mmp2 matrix metallopeptidase 2 treatment ISO RGD PMID:23323009 RGD:13207328 NCBI chrNW_004936475:7,801,356...7,825,831 JBrowse link
G Mmp9 matrix metallopeptidase 9 treatment ISO RGD PMID:23323009 RGD:13207328 NCBI chrNW_004936514:7,038,240...7,045,873 JBrowse link
G Mydgf myeloid derived growth factor severity
treatment
ISO associated with hymenolepiasis RGD PMID:19118508, PMID:20490892, PMID:27055194 RGD:11532263, RGD:39456118, RGD:39456129 NCBI chrNW_004936588:2,706,329...2,716,545 JBrowse link
G Nfe2l2 nuclear factor, erythroid 2 like 2 treatment ISO RGD PMID:22350949 RGD:10412739 NCBI chrNW_004936509:6,589,967...6,621,171 JBrowse link
G Nfkbia NFKB inhibitor alpha treatment ISO RGD PMID:21642017 RGD:10413866 NCBI chrNW_004936494:9,537,793...9,541,187 JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 ISO protein:increased expression:colonic mucosa: RGD PMID:22997830 RGD:13204727 NCBI chrNW_004936475:3,708,069...3,742,845 JBrowse link
G Npy neuropeptide Y treatment ISO RGD PMID:20533056 RGD:10448943 NCBI chrNW_004936478:1,289,437...1,296,819 JBrowse link
G Pdgfra platelet derived growth factor receptor alpha treatment ISO RGD PMID:24115822 RGD:11080973 NCBI chrNW_004936482:16,804,129...16,853,539 JBrowse link
G Pdgfrb platelet derived growth factor receptor beta treatment ISO RGD PMID:24115822 RGD:11080973 NCBI chrNW_004936504:4,762,251...4,799,789 JBrowse link
G Phex phosphate regulating endopeptidase homolog X-linked ISO mRNA:decreased expression:bone: RGD PMID:16890604 RGD:11556253 NCBI chrNW_004936624:2,124,479...2,312,847 JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma susceptibility ISO RGD PMID:20347874 RGD:38599183 NCBI chrNW_004936479:17,084,006...17,112,264 JBrowse link
G Ptger4 prostaglandin E receptor 4 treatment ISO RGD PMID:12100473 RGD:727388 NCBI chrNW_004936518:1,903,636...1,916,746 JBrowse link
G Slc11a1 solute carrier family 11 member 1 ISO RGD PMID:19116231 RGD:5684934 NCBI chrNW_004936569:888,309...895,991 JBrowse link
G Smad4 SMAD family member 4 susceptibility ISO RGD PMID:23090737 RGD:12880038 NCBI chrNW_004936497:12,242,869...12,278,012 JBrowse link
G Tnf tumor necrosis factor treatment ISO RGD PMID:21296062 RGD:8661763 NCBI chrNW_004936727:1,936,066...1,937,766 JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A treatment ISO RGD PMID:21296062 RGD:8661763 NCBI chrNW_004936709:1,407,327...1,421,448 JBrowse link
G Vegfa vascular endothelial growth factor A ISO protein:increased expression:colon RGD PMID:19013462 RGD:5684406 NCBI chrNW_004936476:16,245,134...16,261,180 JBrowse link
ileitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr3 C-C motif chemokine receptor 3 ISO RGD PMID:21945903 RGD:6892917 NCBI chrNW_004936596:223,660...224,739 JBrowse link
G Cd80 CD80 molecule ISO RGD PMID:22068168 RGD:6902902 NCBI chrNW_004936536:6,462,080...6,483,450 JBrowse link
G Il10 interleukin 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27580383 NCBI chrNW_004936557:5,834,874...5,838,502 JBrowse link
G Il17a interleukin 17A ISO mRNA:increased expression:ileum RGD PMID:18536735 RGD:4837793 NCBI chrNW_004936476:8,621,860...8,625,008 JBrowse link
G Itgam integrin subunit alpha M ISO CTD Direct Evidence: marker/mechanism CTD PMID:10647630 NCBI chrNW_004936543:8,460,526...8,508,524 JBrowse link
G Tlr2 toll like receptor 2 ISO RGD PMID:18266231 RGD:2312714 NCBI chrNW_004936576:522,234...531,660 JBrowse link
G Tlr4 toll like receptor 4 ISO RGD PMID:17255219, PMID:18266231 RGD:2312714, RGD:7241089 NCBI chrNW_004936487:6,519,140...6,532,018 JBrowse link
inflammatory bowel disease 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hspa1l heat shock protein family A (Hsp70) member 1 like ISO ClinVar Annotator: match by term: Inflammatory bowel disease 1 ClinVar PMID:28126021 NCBI chrNW_004936727:1,735,880...1,745,231 JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 ISO ClinVar Annotator: match by term: Inflammatory bowel disease 1 ClinVar PMID:11385576, PMID:11385577, PMID:11425413, PMID:11875755, PMID:11910337, PMID:12019468, PMID:12115249, PMID:12512038, PMID:12557156, PMID:12577202, PMID:12626759, PMID:12630966, PMID:14508222, PMID:14765395, PMID:15024686, PMID:15044951, PMID:15190267, PMID:15198989, PMID:15320482, PMID:15459013, PMID:15571588, PMID:15712650, PMID:15770725, PMID:15967635, PMID:16278823, PMID:16485124, PMID:18056399, PMID:18240302, PMID:18419343, PMID:18489434, PMID:18507017, PMID:18541930, PMID:19467619, PMID:19713276, PMID:20032092, PMID:20230816, PMID:20959815, PMID:21274544, PMID:21335489, PMID:21548950, PMID:21830272, PMID:21914217, PMID:21983784, PMID:22319155, PMID:22684479, PMID:22926499, PMID:22942351, PMID:23102769, PMID:24033266, PMID:24391456, PMID:24583628, PMID:24803813, PMID:24960071, PMID:25741868, PMID:26070941, PMID:26164256, PMID:26316104, PMID:26500656, PMID:27306066, PMID:28492532, PMID:28814775 NCBI chrNW_004936475:3,708,069...3,742,845 JBrowse link
G Prkcq protein kinase C theta ISO ClinVar Annotator: match by term: Inflammatory bowel disease 1 ClinVar NCBI chrNW_004936484:8,048,239...8,166,058 JBrowse link
inflammatory bowel disease 10 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg16l1 autophagy related 16 like 1 ISO OMIM NCBI chrNW_004936525:3,973,574...4,010,442 JBrowse link
inflammatory bowel disease 13 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1 ATP binding cassette subfamily B member 1 ISO OMIM NCBI chrNW_004936763:1,225,355...1,308,257 JBrowse link
inflammatory bowel disease 14 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irf5 interferon regulatory factor 5 ISO OMIM NCBI chrNW_004936579:6,138,372...6,149,531 JBrowse link
inflammatory bowel disease 17 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il23r interleukin 23 receptor ISO OMIM NCBI chrNW_004936591:4,365,598...4,425,053 JBrowse link
inflammatory bowel disease 19 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irgm immunity related GTPase M ISO OMIM NCBI chrNW_004936504:4,055,091...4,056,089 JBrowse link
inflammatory bowel disease 25 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il10rb interleukin 10 receptor subunit beta ISO OMIM NCBI chrNW_004936500:9,033,077...9,057,465 JBrowse link
inflammatory bowel disease 28 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il10ra interleukin 10 receptor subunit alpha ISO OMIM NCBI chrNW_004936542:3,099,484...3,113,159 JBrowse link
Inflammatory Bowel Disease 29 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Inava innate immunity activator ISO OMIM NCBI chrNW_004936567:3,443,053...3,458,184 JBrowse link
inflammatory bowel disease 5 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a5 solute carrier family 22 member 5 ISO ClinVar Annotator: match by term: Inflammatory bowel disease 5 ClinVar PMID:15107849, PMID:16333318, PMID:17213842 NCBI chrNW_004936647:2,774,063...2,798,585 JBrowse link
INFLAMMATORY BOWEL DISEASE, IMMUNODEFICIENCY, AND ENCEPHALOPATHY term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tgfb1 transforming growth factor beta 1 ISO OMIM NCBI chrNW_004936661:3,742,080...3,758,266 JBrowse link
ischemic colitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Serpine1 serpin family E member 1 susceptibility ISO DNA:polymorphism:promoter:rs1799768 (human) RGD PMID:25656775 RGD:13208543 NCBI chrNW_004936543:1,032,543...1,040,956 JBrowse link
G Vegfa vascular endothelial growth factor A ISO RGD PMID:15770733 RGD:1580570 NCBI chrNW_004936476:16,245,134...16,261,180 JBrowse link
Neonatal Inflammatory Skin and Bowel Disease 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 ADAM metallopeptidase domain 17 ISO OMIM NCBI chrNW_004936532:5,864,851...5,904,005 JBrowse link
G Iah1 isoamyl acetate hydrolyzing esterase 1 (putative) ISO ClinVar Annotator: match by term: Inflammatory skin and bowel disease, neonatal 1 ClinVar PMID:28492532 NCBI chrNW_004936532:5,853,432...5,864,373 JBrowse link
Neonatal Inflammatory Skin and Bowel Disease 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egfr epidermal growth factor receptor ISO OMIM NCBI chrNW_004936678:365,005...560,546 JBrowse link
Pediatric Crohn's Disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2 coagulation factor II, thrombin ISO RGD PMID:21287673 RGD:5147769 NCBI chrNW_004936562:2,371,725...2,388,617 JBrowse link
G Tnf tumor necrosis factor ISO RGD PMID:11321389 RGD:7394742 NCBI chrNW_004936727:1,936,066...1,937,766 JBrowse link
Proctocolitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1rn interleukin 1 receptor antagonist ISO protein:increased concentration:serum (human) RGD PMID:9802632 RGD:6909134 NCBI chrNW_004936783:1,447,158...1,466,331 JBrowse link
ulcerative colitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1 ATP binding cassette subfamily B member 1 susceptibility ISO RGD PMID:15505619 RGD:1598568 NCBI chrNW_004936763:1,225,355...1,308,257 JBrowse link
G Acsm3 acyl-CoA synthetase medium chain family member 3 ISO mRNA:decreased expression:colonic mucosa RGD PMID:21987487 RGD:7241281 NCBI chrNW_004936501:6,077,366...6,095,432 JBrowse link
G Adcy7 adenylate cyclase 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28067910 NCBI chrNW_004936475:3,368,069...3,393,306 JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO protein:increased expression:serum RGD PMID:16432373 RGD:5686726 NCBI chrNW_004936578:3,168,599...3,179,369 JBrowse link
G Adrb2 adrenoceptor beta 2 ISO protein:decreased expression:large intestine mucosa,spleen RGD PMID:22772914 RGD:7175063 NCBI chrNW_004936504:5,985,407...5,987,453 JBrowse link
G Alpi alkaline phosphatase, intestinal ISO protein:decreased expression:colonic mucosa RGD PMID:22783049 RGD:14367879 NCBI chrNW_004936525:4,616,212...4,619,932 JBrowse link
G Apln apelin ISO protein:increased expression:intestine RGD PMID:17391779 RGD:1626177 NCBI chrNW_004936479:1,889,930...1,899,811 JBrowse link
G Apoa4 apolipoprotein A4 severity ISO DNA:missense mutation:cds:p.Q360H (human) RGD PMID:17206692 RGD:5685660 NCBI chrNW_004936542:2,098,683...2,101,127 JBrowse link
G Aqp7 aquaporin 7 severity ISO mRNA, protein:decreased expression:colon RGD PMID:15338270 RGD:1626292 NCBI chrNW_004936524:1,898,635...1,915,078 JBrowse link
G Arpc2 actin related protein 2/3 complex subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18836448 NCBI chrNW_004936569:758,358...786,995 JBrowse link
G Brinp3 BMP/retinoic acid inducible neural specific 3 ISO mRNA,protein:decreased expression:intestine RGD PMID:25171508 RGD:14398484 NCBI chrNW_004936481:711,356...1,067,856 JBrowse link
G Btnl2 butyrophilin like 2 susceptibility ISO DNA:SNPs: : rs2294881,rs9268480,rs2076523(human) RGD PMID:19659809 RGD:9685032 NCBI chrNW_004936727:567,656...587,784 JBrowse link
G Card9 caspase recruitment domain family member 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chrNW_004936669:1,428,208...1,438,012 JBrowse link
G Casp3 caspase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24055189 NCBI chrNW_004936554:4,571,072...4,593,765 JBrowse link
G Ccl20 C-C motif chemokine ligand 20 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:16306769, PMID:21887805 RGD:7488892 NCBI chrNW_004936525:8,238,128...8,240,974 JBrowse link
G Ccny cyclin Y ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438405 NCBI chrNW_004936574:3,638,054...3,849,154 JBrowse link
G Ccr3 C-C motif chemokine receptor 3 ISO RGD PMID:21077277 RGD:6892920 NCBI chrNW_004936596:223,660...224,739 JBrowse link
G Ccr6 C-C motif chemokine receptor 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16306769 NCBI chrNW_004936489:16,669,297...16,689,451 JBrowse link
G Cd40 CD40 molecule ISO protein:increased expression:intestine, epithelial cell RGD PMID:20133813 RGD:5490590 NCBI chrNW_004936514:6,936,915...6,947,246 JBrowse link
G Cdh1 cadherin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19915572 NCBI chrNW_004936475:18,990,529...19,065,954 JBrowse link
G Cdh3 cadherin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19915572 NCBI chrNW_004936475:18,908,031...18,954,402 JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A disease_progression ISO RGD PMID:15743319 RGD:8662406 NCBI chrNW_004936476:22,717,308...22,725,127 JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain ISO Protein:increased expression:large intestine mucosa RGD PMID:17011522 RGD:1600887 NCBI chrNW_004936778:847,473...943,038 JBrowse link
G Col1a1 collagen type I alpha 1 chain ISO RGD PMID:17939044 RGD:5688304 NCBI chrNW_004936490:11,448,552...11,465,836 JBrowse link
G Cxcl8 C-X-C motif chemokine ligand 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12133438, PMID:15955209 NCBI chrNW_004936598:1,779,471...1,781,353 JBrowse link
G Cxcr1 C-X-C motif chemokine receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chrNW_004936569:715,129...716,187 JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 ISO mRNA:increased expression:peripheral blood immature plasma cells RGD PMID:21087446 RGD:6480657 NCBI chrNW_004936762:66,636...69,694 JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 ISO mRNA:increased expression:peripheral blood immature plasma cells RGD PMID:21087446 RGD:6480657 NCBI chrNW_004936469:39,794,613...39,798,448 JBrowse link
G Ecm1 extracellular matrix protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438406 NCBI chrNW_004936580:750,423...756,765 JBrowse link
G Esr2 estrogen receptor 2 ISO mRNA:decreased expression:colon RGD PMID:21252046 RGD:5508810 NCBI chrNW_004936495:7,956,168...8,018,356 JBrowse link
G F2 coagulation factor II, thrombin ISO RGD PMID:21593018 RGD:5147754 NCBI chrNW_004936562:2,371,725...2,388,617 JBrowse link
G Fas Fas cell surface death receptor treatment ISO RGD PMID:30122878 RGD:13792562 NCBI chrNW_004936735:209,369...234,582 JBrowse link
G Faslg Fas ligand treatment ISO RGD PMID:30122878 RGD:13792562 NCBI chrNW_004936481:14,789,547...14,795,780 JBrowse link
G Gc GC vitamin D binding protein susceptibility ISO DNA:polymorphism:cds:p.T420K(human) RGD PMID:21832969 RGD:5509866 NCBI chrNW_004936598:3,220,029...3,256,091 JBrowse link
G Ghrl ghrelin and obestatin prepropeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:19617644 NCBI chrNW_004936602:3,037,862...3,044,863 JBrowse link
G Gna12 G protein subunit alpha 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chrNW_004936823:447,979...543,134 JBrowse link
G Gpr65 G protein-coupled receptor 65 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30616622 NCBI chrNW_004936488:15,544,075...15,545,344 JBrowse link
G Gpx1 glutathione peroxidase 1 ISO protein:decreased expression:erythrocyte RGD PMID:20186929 RGD:11352754 NCBI chrNW_004936529:997,943...999,123 JBrowse link
G Herc2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438405 NCBI chrNW_004936471:38,419,147...38,606,312 JBrowse link
G Hnf4a hepatocyte nuclear factor 4 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:19915572 NCBI chrNW_004936530:2,401,053...2,425,989 JBrowse link
G Hnmt histamine N-methyltransferase ISO RGD PMID:18340362 RGD:5509777 NCBI chrNW_004936469:38,125,877...38,166,429 JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 ISO protein:increased expression:colon mucosa, epithelium (human) RGD PMID:22297444 RGD:5688753 NCBI chrNW_004936647:2,087,650...2,133,343 JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:substantia nigra (rat)
CTD
RGD
PMID:15553846, PMID:20584104 RGD:4145388 NCBI chrNW_004936659:616,570...627,172 JBrowse link
G Icoslg inducible T cell costimulator ligand ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chrNW_004936500:164,659...173,144 JBrowse link
G Igf1r insulin like growth factor 1 receptor ISO protein:altered expression:colon RGD PMID:18938767 RGD:5686432 NCBI chrNW_004936483:4,563,995...4,860,231 JBrowse link
G Igf2 insulin like growth factor 2 disease_progression ISO RGD PMID:16088202 RGD:5509966 NCBI chrNW_004936816:972,902...981,232 JBrowse link
G Ikzf1 IKAROS family zinc finger 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chrNW_004936686:1,459,582...1,556,478 JBrowse link
G Il10 interleukin 10 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:18836448, PMID:20228799, PMID:26660358, PMID:28120341 RGD:14975153, RGD:14975255 NCBI chrNW_004936557:5,834,874...5,838,502 JBrowse link
G Il12b interleukin 12B ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438406, PMID:20228799, PMID:21297633 NCBI chrNW_004936515:4,056,214...4,066,121 JBrowse link
G Il18rap interleukin 18 receptor accessory protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chrNW_004936713:1,087,884...1,115,512 JBrowse link
G Il1b interleukin 1 beta ISO protein:increased expression:lung
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:12133438, PMID:15955209, PMID:20452301, PMID:22119283, PMID:24812904 RGD:10450593 NCBI chrNW_004936783:1,251,678...1,256,807 JBrowse link
G Il1r2 interleukin 1 receptor type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chrNW_004936713:679,680...716,801 JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO DNA:repeats:intron:IVS2+914_1000dup IL1RN*2 (human) RGD PMID:8119534 RGD:6909136 NCBI chrNW_004936783:1,447,158...1,466,331 JBrowse link
G Il23r interleukin 23 receptor ISO CTD Direct Evidence: marker/mechanism
DNA:SNP,Haplotype: :rs1884444(human)
CTD
RGD
PMID:18438406, PMID:19122664, PMID:20228799, PMID:23093364 RGD:8549574 NCBI chrNW_004936591:4,365,598...4,425,053 JBrowse link
G Il33 interleukin 33 severity
treatment
ISO mRNA:increased expression:sigmoid colon RGD PMID:21037074, PMID:25112700, PMID:28802904 RGD:39938951, RGD:39938966, RGD:40813742 NCBI chrNW_004936539:763,755...791,461 JBrowse link
G Il7r interleukin 7 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chrNW_004936518:5,815,820...5,842,571 JBrowse link
G Irf5 interferon regulatory factor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chrNW_004936579:6,138,372...6,149,531 JBrowse link
G Irgm immunity related GTPase M ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chrNW_004936504:4,055,091...4,056,089 JBrowse link
G Jak2 Janus kinase 2 ISO CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs10758669 (human)
CTD
RGD
PMID:20228799, PMID:21297633, PMID:22269120 RGD:6483020 NCBI chrNW_004936503:111,722...243,627 JBrowse link
G Kdr kinase insert domain receptor ISO protein:increased expression:colon RGD PMID:19013462 RGD:5684406 NCBI chrNW_004936482:17,537,697...17,581,320 JBrowse link
G Kif21b kinesin family member 21B ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chrNW_004936567:3,346,655...3,394,656 JBrowse link
G Lamb1 laminin subunit beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19915572 NCBI chrNW_004936479:16,177,200...16,245,268 JBrowse link
G Lsp1 lymphocyte specific protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chrNW_004936816:752,021...786,998 JBrowse link
G Ltf lactotransferrin ISO CTD Direct Evidence: therapeutic CTD PMID:16640825 NCBI chrNW_004936596:344,287...373,788 JBrowse link
G Masp2 mannan binding lectin serine peptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12904520 NCBI chrNW_004936474:100,584...113,781 JBrowse link
G Mmp1 matrix metallopeptidase 1 ISO RGD PMID:18837084 RGD:7207395 NCBI chrNW_004936551:5,167,909...5,175,149 JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22119283 NCBI chrNW_004936514:7,038,240...7,045,873 JBrowse link
G Mpo myeloperoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20380826, PMID:22119283, PMID:24055189 NCBI chrNW_004936490:4,809,773...4,819,070 JBrowse link
G Mst1 macrophage stimulating 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438406, PMID:20228799 NCBI chrNW_004936529:1,298,853...1,306,088 JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase susceptibility ISO DNA:polymorphism: :66A>G (human) RGD PMID:21947961 RGD:5508217 NCBI chrNW_004936643:379,790...410,034 JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming ISO mRNA:altered expression: : RGD PMID:12870797 RGD:2324685 NCBI chrNW_004936816:60,499...91,628 JBrowse link
G Nkx2-3 NK2 homeobox 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438405, PMID:18438406, PMID:20228799 NCBI chrNW_004936636:529,669...532,237 JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20452301 NCBI chrNW_004936475:3,708,069...3,742,845 JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chrNW_004936490:15,069,435...15,076,112 JBrowse link
G Pon1 paraoxonase 1 ISO mRNA:decreased expression:colon RGD PMID:17664137 RGD:5509924 NCBI chrNW_004936585:4,954,871...4,979,560 JBrowse link
G Pon3 paraoxonase 3 ISO mRNA:decreased expression:colon RGD PMID:17664137 RGD:5509924 NCBI chrNW_004936585:4,902,430...4,928,377 JBrowse link
G Prdm1 PR/SET domain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chrNW_004936564:2,594,362...2,690,680 JBrowse link
G Psmg1 proteasome assembly chaperone 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chrNW_004936500:3,997,415...4,006,394 JBrowse link
G Ptger4 prostaglandin E receptor 4 ISO RGD PMID:21818367 RGD:6483532 NCBI chrNW_004936518:1,903,636...1,916,746 JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO RGD PMID:17429720 RGD:2300267 NCBI chrNW_004936487:10,745,465...10,758,812 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:17429720 RGD:2300267 NCBI chrNW_004936481:3,821,564...3,828,086 JBrowse link
G Ptpn2 protein tyrosine phosphatase non-receptor type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438405 NCBI chrNW_004936626:2,390,004...2,472,039 JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:15955209 NCBI chrNW_004936599:3,800,142...3,810,583 JBrowse link
G Ripk2 receptor interacting serine/threonine kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20452301 NCBI chrNW_004936544:3,606,925...3,653,248 JBrowse link
G Rnf170 ring finger protein 170 ISO ClinVar Annotator: match by term: Ulcerative colitis ClinVar PMID:30311386 NCBI chrNW_004937108:111,111...147,077 JBrowse link
G Sell selectin L ISO DNA:polymorphism: :p.F206L (human) RGD PMID:19212205 RGD:13464267 NCBI chrNW_004936481:17,022,421...17,032,105 JBrowse link
G Selp selectin P ISO protein:increased expression:serum RGD PMID:21526498 RGD:6218993 NCBI chrNW_004936481:17,076,660...17,112,501 JBrowse link
G Slc11a1 solute carrier family 11 member 1 ISO DNA:transition, repeat:promoter:-237C>T (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:promoter (human)
RGD
CTD
PMID:11929588, PMID:16059695, PMID:18340647 RGD:5684939, RGD:5684968 NCBI chrNW_004936569:888,309...895,991 JBrowse link
G Slc26a3 solute carrier family 26 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19915573 NCBI chrNW_004936479:16,350,746...16,374,911 JBrowse link
G Sphk1 sphingosine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24055189 NCBI chrNW_004936594:1,482,830...1,489,337 JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs744166 (human)
CTD
RGD
PMID:18438405, PMID:20228799, PMID:22269120 RGD:6483020 NCBI chrNW_004936490:17,119,189...17,178,402 JBrowse link
G Syne1 spectrin repeat containing nuclear envelope protein 1 ISO ClinVar Annotator: match by term: Ulcerative colitis ClinVar PMID:30311386 NCBI chrNW_004936489:4,903,176...5,177,987 JBrowse link
G Thbd thrombomodulin ISO protein:decreased expression:colon, blood vessel RGD PMID:17557119 RGD:5685011 NCBI chrNW_004936620:2,563,900...2,568,117 JBrowse link
G Tnf tumor necrosis factor treatment ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:lung
CTD
RGD
PMID:19617644, PMID:20452301, PMID:22119283, PMID:24812904, PMID:25204186, PMID:28120341 RGD:10450577, RGD:10450593, RGD:14975153 NCBI chrNW_004936727:1,936,066...1,937,766 JBrowse link
G Tnfsf15 TNF superfamily member 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chrNW_004936487:3,959,224...3,975,959 JBrowse link
G Vcam1 vascular cell adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15553846 NCBI chrNW_004936748:785,491...802,791 JBrowse link
G Vegfa vascular endothelial growth factor A ISO protein:increased expression:colon, plasma RGD PMID:19013462 RGD:5684406 NCBI chrNW_004936476:16,245,134...16,261,180 JBrowse link
G Vip vasoactive intestinal peptide severity ISO mRNA:decreased expression:colon RGD PMID:22143367 RGD:5685619 NCBI chrNW_004936489:5,425,778...5,434,483 JBrowse link
G Vipr1 vasoactive intestinal peptide receptor 1 ISO RGD PMID:17611633 RGD:5685618 NCBI chrNW_004936695:2,564,917...2,597,009 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 11962
    disease of anatomical entity 11526
      gastrointestinal system disease 3786
        intestinal disease 1300
          inflammatory bowel disease 280
            Crohn's disease + 87
            INFLAMMATORY BOWEL DISEASE, IMMUNODEFICIENCY, AND ENCEPHALOPATHY 1
            Inflammatory Bowel Disease 29 1
            Inflammatory Bowel Disease 30 0
            Neonatal Inflammatory Skin and Bowel Disease + 3
            colitis + 197
            inflammatory bowel disease 1 3
            inflammatory bowel disease 10 1
            inflammatory bowel disease 11 0
            inflammatory bowel disease 12 0
            inflammatory bowel disease 13 1
            inflammatory bowel disease 14 1
            inflammatory bowel disease 15 0
            inflammatory bowel disease 16 0
            inflammatory bowel disease 17 1
            inflammatory bowel disease 18 0
            inflammatory bowel disease 19 1
            inflammatory bowel disease 2 0
            inflammatory bowel disease 20 0
            inflammatory bowel disease 21 0
            inflammatory bowel disease 22 0
            inflammatory bowel disease 23 0
            inflammatory bowel disease 24 0
            inflammatory bowel disease 25 1
            inflammatory bowel disease 26 0
            inflammatory bowel disease 27 0
            inflammatory bowel disease 28 1
            inflammatory bowel disease 3 0
            inflammatory bowel disease 4 0
            inflammatory bowel disease 5 1
            inflammatory bowel disease 6 0
            inflammatory bowel disease 7 0
            inflammatory bowel disease 8 0
            inflammatory bowel disease 9 0
            ulcerative colitis + 99
Path 2
Term Annotations click to browse term
  disease 11962
    disease of anatomical entity 11526
      Immune & Inflammatory Diseases 2756
        Inflammation 1680
          gastroenteritis 350
            inflammatory bowel disease 280
              Crohn's disease + 87
              INFLAMMATORY BOWEL DISEASE, IMMUNODEFICIENCY, AND ENCEPHALOPATHY 1
              Inflammatory Bowel Disease 29 1
              Inflammatory Bowel Disease 30 0
              Neonatal Inflammatory Skin and Bowel Disease + 3
              colitis + 197
              inflammatory bowel disease 1 3
              inflammatory bowel disease 10 1
              inflammatory bowel disease 11 0
              inflammatory bowel disease 12 0
              inflammatory bowel disease 13 1
              inflammatory bowel disease 14 1
              inflammatory bowel disease 15 0
              inflammatory bowel disease 16 0
              inflammatory bowel disease 17 1
              inflammatory bowel disease 18 0
              inflammatory bowel disease 19 1
              inflammatory bowel disease 2 0
              inflammatory bowel disease 20 0
              inflammatory bowel disease 21 0
              inflammatory bowel disease 22 0
              inflammatory bowel disease 23 0
              inflammatory bowel disease 24 0
              inflammatory bowel disease 25 1
              inflammatory bowel disease 26 0
              inflammatory bowel disease 27 0
              inflammatory bowel disease 28 1
              inflammatory bowel disease 3 0
              inflammatory bowel disease 4 0
              inflammatory bowel disease 5 1
              inflammatory bowel disease 6 0
              inflammatory bowel disease 7 0
              inflammatory bowel disease 8 0
              inflammatory bowel disease 9 0
              ulcerative colitis + 99
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.